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ONTOLOGY REPORT - ANNOTATIONS

Term:heparin proteoglycan catabolic process
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Accession:GO:0030211 term browser browse the term
Definition:The chemical reactions and pathways resulting in the breakdown of heparin proteoglycans, which consist of a core protein linked to a heparin glycosaminoglycan. The heparin chain is composed of the repeating disaccharide unit beta-(1,4)-N-acetyl-D-glucosamine-alpha-(1,4)-hexuronic acid, the former being either sulfated or deacetylated on its amino group as well as sulfated on one of its hydroxyl groups and the latter being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids. Heparin is similar to heparan sulfate but it contains more N-sulfate and O-sulfate groups.
Synonyms:exact_synonym: heparin breakdown;   heparin catabolism;   heparin degradation
 related_synonym: heparan sulfate catabolic process


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heparin proteoglycan catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idua alpha-L-iduronidase acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:21873421)
MGI:2176236|MGI:4415188 (PMID:19751987), (PMID:19834056), (PMID:21873421)
GO_REF:0000107
GO_REF:0000117 		RGD
Ensembl
UniProt		 PMID:19751987 PMID:19834056 PMID:21873421 GO_REF:0000107 GO_REF:0000117 NCBI chr14:1,175,994...1,203,913
Ensembl chr14:1,176,577...1,204,066 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      metabolic process 12252
        carbohydrate derivative metabolic process 1055
          glycoprotein metabolic process 362
            glycoprotein catabolic process 36
              proteoglycan catabolic process 19
                heparin proteoglycan catabolic process 1
Path 2
Term Annotations click to browse term
  biological_process 20668
    cellular process 19605
      metabolic process 12252
        macromolecule metabolic process 10074
          protein metabolic process 5265
            glycoprotein metabolic process 362
              proteoglycan metabolic process 104
                proteoglycan catabolic process 19
                  heparin proteoglycan catabolic process 1
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