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ONTOLOGY REPORT - ANNOTATIONS

Term:heparin biosynthetic process
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Accession:GO:0030210 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
Synonyms:exact_synonym: heparin anabolism;   heparin biosynthesis;   heparin formation;   heparin synthesis
 related_synonym: heparan sulfate biosynthetic process


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heparin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO
IEA		 (PMID:19297368)
GO_REF:0000107		 RGD
Ensembl		 PMID:19297368 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within
acts_upstream_of_or_within_positive_effect		 ISO MGI:108050 (PMID:21148566), (PMID:21310272)
(PMID:10926768), (PMID:15161920), (PMID:15177029), (PMID:18480751)		 RGD PMID:10926768 PMID:15161920 PMID:15177029 PMID:18480751 PMID:21148566 More... NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (PMID:21310272) RGD PMID:21310272 NCBI chr 3:79,665,414...79,798,077
Ensembl chr 3:79,665,415...79,798,059 		JBrowse link
G Glce glucuronic acid epimerase involved_in IEA
ISO		 GO_REF:0000041
(MGI:2135754|PMID:11279150)		 UniProt
RGD		 PMID:11279150 GO_REF:0000041 MGI:2135754 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040 		JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191 		JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr15:3,563,515...3,573,801
Ensembl chr15:3,563,358...3,573,801 		JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584 		JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:213,787,010...214,119,514
Ensembl chr 2:213,787,006...214,115,373 		JBrowse link
G Slc10a7 solute carrier family 10, member 7 involved_in ISO (PMID:30082715)
(MGI:6198941|PMID:30082715)		 RGD PMID:30082715 MGI:6198941 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464 		JBrowse link
G Xylt2 xylosyltransferase 2 acts_upstream_of_or_within ISO MGI:3714171 (PMID:17517600) RGD PMID:17517600 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        sulfur compound metabolic process 339
          heparin metabolic process 16
            heparin biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 20134
    cellular process 19326
      metabolic process 12309
        macromolecule metabolic process 10164
          aminoglycan metabolic process 117
            glycosaminoglycan metabolic process 103
              mucopolysaccharide metabolic process 83
                heparin metabolic process 16
                  heparin biosynthetic process 10
paths to the root