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ONTOLOGY REPORT - ANNOTATIONS


Term:heparin biosynthetic process
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Accession:GO:0030210 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
Synonyms:exact_synonym: heparin anabolism;   heparin biosynthesis;   heparin formation;   heparin synthesis
 related_synonym: heparan sulfate biosynthetic process



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heparin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angpt1 angiopoietin 1 involved_in ISO
IEA
(PMID:19297368)
GO_REF:0000107
RGD
Ensembl
PMID:19297368 GO_REF:0000107 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within_positive_effect ISO (MGI:1888607|PMID:10926768), (MGI:3050709|PMID:15161920), (MGI:3051956|PMID:15177029), (MGI:4360160|PMID:18480751)
MGI:108050 (MGI:6406739|PMID:21310272), (MGI:6406770|PMID:21148566)
RGD PMID:10926768 PMID:15161920 PMID:15177029 PMID:18480751 PMID:21148566 More... MGI:1888607 MGI:3050709 MGI:3051956 MGI:4360160 MGI:6406739 MGI:6406770 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Ext2 exostosin glycosyltransferase 2 acts_upstream_of_or_within ISO MGI:894663 (MGI:6406739|PMID:21310272) RGD PMID:21310272 MGI:6406739 NCBI chr 3:79,665,415...79,798,077
Ensembl chr 3:79,665,415...79,798,059
JBrowse link
G Glce glucuronic acid epimerase involved_in IEA
ISO
GO_REF:0000041
(MGI:2135754|PMID:11279150)
UniProt
RGD
PMID:11279150 GO_REF:0000041 MGI:2135754 NCBI chr 8:62,546,104...62,612,144
Ensembl chr 8:62,546,107...62,612,040
JBrowse link
G Ndst1 N-deacetylase and N-sulfotransferase 1 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr15:3,563,358...3,573,801
Ensembl chr15:3,563,358...3,573,801
JBrowse link
G Ndst3 N-deacetylase and N-sulfotransferase 3 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:211,702,728...211,868,159
Ensembl chr 2:211,704,898...211,854,584
JBrowse link
G Ndst4 N-deacetylase and N-sulfotransferase 4 involved_in IEA GO_REF:0000041 UniProt GO_REF:0000041 NCBI chr 2:213,787,010...214,116,569
Ensembl chr 2:213,787,006...214,115,373
JBrowse link
G Slc10a7 solute carrier family 10, member 7 involved_in ISO (PMID:30082715)
(MGI:6198941|PMID:30082715)
RGD PMID:30082715 MGI:6198941 NCBI chr19:29,183,143...29,407,470
Ensembl chr19:29,183,155...29,407,464
JBrowse link
G Xylt2 xylosyltransferase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3714171 (MGI:3713963|PMID:17517600)
Ensembl
RGD
PMID:17517600 GO_REF:0000107 MGI:3713963 NCBI chr10:79,605,910...79,619,482
Ensembl chr10:79,606,007...79,619,391
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      cellular metabolic process 10719
        sulfur compound metabolic process 329
          sulfur compound biosynthetic process 111
            heparin biosynthetic process 10
Path 2
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      organic substance metabolic process 11355
        macromolecule metabolic process 9812
          aminoglycan metabolic process 113
            glycosaminoglycan metabolic process 99
              mucopolysaccharide metabolic process 79
                heparin metabolic process 15
                  heparin biosynthetic process 10
paths to the root