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ONTOLOGY REPORT - ANNOTATIONS


Term:chondroitin sulfate biosynthetic process
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Accession:GO:0030206 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
Synonyms:exact_synonym: chondroitin sulfate anabolism;   chondroitin sulfate biosynthesis;   chondroitin sulfate formation;   chondroitin sulfate synthesis;   chondroitin sulphate biosynthesis;   chondroitin sulphate biosynthetic process


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chondroitin sulfate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3GALT6 beta-1,3-galactosyltransferase 6 involved_in IEA UniProt GO_REF:0000041 NCBI chr 1:1,232,237...1,235,041
Ensembl chr 1:1,232,237...1,235,041
JBrowse link
G BCAN brevican involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr 1:156,642,117...156,659,528
Ensembl chr 1:156,641,390...156,659,532
JBrowse link
G BGN biglycan involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr  X:153,494,980...153,509,546
Ensembl chr  X:153,494,980...153,509,546
JBrowse link
G CHPF chondroitin polymerizing factor involved_in
acts_upstream_of_or_within
IBA
ISO
IDA
TAS
(PMID:21873635)
(MGI:5462280|PMID:22952873)
(MGI:5462286|PMID:22952769)
(PMID:12761225)
GO_Central
MGI
FlyBase
Reactome
PMID:12761225 PMID:21873635 PMID:22952769 PMID:22952873 MGI:5462280 MGI:5462286 Reactome:R-HSA-2022870 NCBI chr 2:219,538,949...219,543,809
Ensembl chr 2:219,538,948...219,543,809
JBrowse link
G CHPF2 chondroitin polymerizing factor 2 involved_in IBA
TAS
(PMID:21873635) GO_Central
Reactome
PMID:21873635 Reactome:R-HSA-2022870 NCBI chr 7:151,232,483...151,238,822
Ensembl chr 7:151,232,489...151,238,827
JBrowse link
G CHST11 carbohydrate sulfotransferase 11 involved_in
acts_upstream_of_or_within
IDA
ISO
TAS
(PMID:11056388)
(MGI:4941099|PMID:21138417)
(MGI:1354846|PMID:10722746)
UniProt
MGI
Reactome
PMID:10722746 PMID:11056388 PMID:21138417 MGI:1354846 MGI:4941099 Reactome:R-HSA-2022870 NCBI chr12:104,456,948...104,762,014
Ensembl chr12:104,455,295...104,762,014
JBrowse link
G CHST12 carbohydrate sulfotransferase 12 involved_in IDA
TAS
(PMID:10781601) UniProt
Reactome
PMID:10781601 Reactome:R-HSA-2022870 NCBI chr 7:2,403,489...2,448,484
Ensembl chr 7:2,403,588...2,448,484
JBrowse link
G CHST13 carbohydrate sulfotransferase 13 involved_in TAS
IDA
(PMID:12080076) Reactome
UniProt
PMID:12080076 Reactome:R-HSA-2022870 NCBI chr 3:126,524,155...126,543,291
Ensembl chr 3:126,524,155...126,543,291
JBrowse link
G CHST15 carbohydrate sulfotransferase 15 involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr10:124,006,059...124,093,684
Ensembl chr10:124,007,668...124,093,598
JBrowse link
G CHST3 carbohydrate sulfotransferase 3 involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
TAS
(PMID:9883891)
(MGI:1206144|PMID:9597547)
(MGI:2156294|PMID:11696535)
(PMID:21873635)
UniProt
MGI
GO_Central
Reactome
PMID:9597547 PMID:9883891 PMID:11696535 PMID:21873635 MGI:1206144 MGI:2156294 Reactome:R-HSA-2022870 NCBI chr10:71,964,395...72,013,562
Ensembl chr10:71,964,395...72,013,558
JBrowse link
G CHST7 carbohydrate sulfotransferase 7 involved_in IDA
IBA
TAS
(PMID:10781596)
(PMID:21873635)
UniProt
GO_Central
Reactome
PMID:10781596 PMID:21873635 Reactome:R-HSA-2022870 NCBI chr  X:46,573,765...46,598,496
Ensembl chr  X:46,573,765...46,598,496
JBrowse link
G CHST9 carbohydrate sulfotransferase 9 involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr18:26,906,481...27,185,364
Ensembl chr18:26,906,481...27,185,308
JBrowse link
G CHSY1 chondroitin sulfate synthase 1 involved_in
acts_upstream_of_or_within
IBA
IDA
TAS
(PMID:21873635)
(PMID:11514575)
GO_Central
MGI
Reactome
PMID:11514575 PMID:21873635 Reactome:R-HSA-2022870 NCBI chr15:101,175,727...101,252,048
Ensembl chr15:101,175,727...101,252,048
JBrowse link
G CHSY3 chondroitin sulfate synthase 3 involved_in TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-2022870 NCBI chr 5:129,903,384...130,186,637
Ensembl chr 5:129,904,465...130,186,634
JBrowse link
G CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 involved_in IBA
TAS
IDA
(PMID:21873635)
(PMID:11514575), (PMID:12163485)
GO_Central
Reactome
UniProt
PMID:11514575 PMID:12163485 PMID:21873635 Reactome:R-HSA-2022870 NCBI chr 8:19,404,161...19,757,908
Ensembl chr 8:19,404,161...19,758,029
JBrowse link
G CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 involved_in TAS
IBA
(PMID:21873635) Reactome
GO_Central
PMID:21873635 Reactome:R-HSA-2022870 NCBI chr10:43,138,445...43,185,308
Ensembl chr10:43,138,445...43,185,302
JBrowse link
G CSPG4 chondroitin sulfate proteoglycan 4 involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr15:75,674,322...75,712,848
Ensembl chr15:75,674,322...75,712,848
JBrowse link
G CSPG5 chondroitin sulfate proteoglycan 5 involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr 3:47,562,238...47,580,240
Ensembl chr 3:47,562,238...47,580,792
JBrowse link
G DCN decorin involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr12:91,140,484...91,182,817
Ensembl chr12:91,140,484...91,183,217
JBrowse link
G DSE dermatan sulfate epimerase involved_in IEA UniProt GO_REF:0000041 NCBI chr 6:116,254,171...116,444,861
Ensembl chr 6:116,254,173...116,444,861
JBrowse link
G NCAN neurocan involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr19:19,211,958...19,252,233
Ensembl chr19:19,211,958...19,252,233
JBrowse link
G SLC35D1 solute carrier family 35 member D1 acts_upstream_of_or_within ISO (MGI:3771453|PMID:17952091) MGI PMID:17952091 MGI:3771453 NCBI chr 1:66,999,350...67,054,423
Ensembl chr 1:66,999,350...67,054,148
JBrowse link
G UGDH UDP-glucose 6-dehydrogenase involved_in ISS UniProt GO_REF:0000024 NCBI chr 4:39,498,755...39,527,439
Ensembl chr 4:39,498,755...39,528,311
JBrowse link
G VCAN versican involved_in TAS Reactome Reactome:R-HSA-2022870 NCBI chr 5:83,471,744...83,582,302
Ensembl chr 5:83,471,618...83,582,303
JBrowse link
G XYLT1 xylosyltransferase 1 involved_in IEA UniProt GO_REF:0000041 NCBI chr16:17,101,769...17,470,960
Ensembl chr16:17,101,769...17,470,960
JBrowse link
G XYLT2 xylosyltransferase 2 involved_in IEA UniProt GO_REF:0000041 NCBI chr17:50,346,126...50,361,185
Ensembl chr17:50,346,126...50,363,138
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18666
    metabolic process 12186
      cellular metabolic process 11202
        cellular biosynthetic process 6351
          sulfur compound biosynthetic process 198
            chondroitin sulfate biosynthetic process 26
Path 2
Term Annotations click to browse term
  biological_process 18666
    metabolic process 12186
      organic substance metabolic process 11700
        macromolecule metabolic process 10121
          protein metabolic process 6031
            glycoprotein metabolic process 432
              proteoglycan metabolic process 94
                chondroitin sulfate proteoglycan metabolic process 48
                  chondroitin sulfate metabolic process 42
                    chondroitin sulfate biosynthetic process 26
paths to the root