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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation


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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen dependent TFPI regulating protein involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:41,916,621...42,001,092
Ensembl chr13:41,916,624...42,001,160 		JBrowse link
G Anxa5 annexin A5 involved_in ISO RGD
MGI		 PMID:20684318 GO_REF:0000096 MGI:4417868 RGD:7241850 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043 		JBrowse link
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G Apoh apolipoprotein H involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222 		JBrowse link
G Kng1 kininogen 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828 		JBrowse link
G Kng2 kininogen 2 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr16:22,804,602...22,847,851
Ensembl chr16:22,804,604...22,848,232 		JBrowse link
G Proc protein C acts_upstream_of_or_within
involved_in		 ISO
IMP
IDA
IBA		 (PMID:9788960)
(PMID:9616155)		 RGD
MGI
GO_Central		 PMID:1440533 PMID:9616155 PMID:9788960 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:11100042 NCBI chr18:32,256,179...32,272,623
Ensembl chr18:32,256,179...32,272,623 		JBrowse link
G Psg23 pregnancy-specific beta-1-glycoprotein 23 acts_upstream_of_or_within IDA (PMID:23469002) MGI PMID:23469002 NCBI chr 7:18,340,268...18,350,426
Ensembl chr 7:18,340,268...18,350,426 		JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 involved_in ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119 		JBrowse link
G Tpsab1 tryptase alpha/beta 1 acts_upstream_of_or_within TAS (PMID:9395536) MGI PMID:9395536 NCBI chr17:25,562,219...25,564,536
Ensembl chr17:25,562,212...25,564,541 		JBrowse link
G Tspan8 tetraspanin 8 involved_in ISO RGD
MGI		 PMID:9531564 GO_REF:0000096 MGI:4417868 RGD:634231 NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798 		JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 acts_upstream_of_or_within IMP (PMID:14702107) MGI PMID:14702107 NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077 		JBrowse link
G Cpb2 carboxypeptidase B2 involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:11848438 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:632532 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995 		JBrowse link
G F12 coagulation factor XII (Hageman factor) acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606 		JBrowse link
G F2 coagulation factor II involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934 		JBrowse link
G Fgb fibrinogen beta chain involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170 		JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356 		JBrowse link
G Gp1ba glycoprotein 1b, alpha polypeptide involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:70,529,928...70,534,812
Ensembl chr11:70,529,948...70,532,862 		JBrowse link
G Hrg histidine-rich glycoprotein acts_upstream_of IMP (PMID:15869579) MGI PMID:15869579 NCBI chr16:22,769,822...22,780,409
Ensembl chr16:22,769,822...22,780,406 		JBrowse link
G Klkb1 kallikrein B, plasma 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896 		JBrowse link
G Plau plasminogen activator, urokinase involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:9733098) GO_Central
MGI		 PMID:9733098 GO_REF:0000033 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plg plasminogen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
G Pros1 protein S (alpha) acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr16:62,674,670...62,749,709
Ensembl chr16:62,674,670...62,749,709 		JBrowse link
G Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 acts_upstream_of_or_within IEA UniProt GO_REF:0000043 MGI:1354194 NCBI chr 2:84,595,704...84,605,748
Ensembl chr 2:84,595,731...84,605,788 		JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222 		JBrowse link
G Cpb2 carboxypeptidase B2 involved_in ISO RGD
MGI		 PMID:17002650 GO_REF:0000096 MGI:4417868 RGD:2313647 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:15869579) GO_Central
MGI		 PMID:15869579 GO_REF:0000033 NCBI chr16:22,769,822...22,780,409
Ensembl chr16:22,769,822...22,780,406 		JBrowse link
G Plat plasminogen activator, tissue involved_in NAS (MGI:6869957|PMID:8508955) ComplexPortal PMID:8508955 MGI:6869957 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860 		JBrowse link
G Plau plasminogen activator, urokinase involved_in NAS (MGI:6869957|PMID:8508955) ComplexPortal PMID:8508955 MGI:6869957 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plg plasminogen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 involved_in NAS
ISO		 (MGI:6869957|PMID:8508955), (MGI:6869973|PMID:1695900) ComplexPortal
MGI		 PMID:1695900 PMID:8508955 GO_REF:0000119 MGI:4834177 MGI:6869957 MGI:6869973 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122 		JBrowse link
G Serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 involved_in ISO RGD
MGI		 PMID:6506034 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:1625541 NCBI chr11:75,322,562...75,330,327
Ensembl chr11:75,322,558...75,330,417 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Vtn vitronectin involved_in NAS (MGI:6869973|PMID:1695900) ComplexPortal PMID:1695900 MGI:6869973 NCBI chr11:78,389,946...78,393,151
Ensembl chr11:78,389,917...78,393,150 		JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113 		JBrowse link
G C1qtnf1 C1q and tumor necrosis factor related protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:118,319,187...118,342,608
Ensembl chr11:118,319,029...118,340,789 		JBrowse link
G Gp5 glycoprotein 5 platelet acts_upstream_of_or_within IMP (PMID:10557321), (PMID:11435305) MGI PMID:10557321 PMID:11435305 NCBI chr16:30,126,503...30,129,599
Ensembl chr16:30,126,503...30,129,597 		JBrowse link
G Pdgfa platelet derived growth factor, alpha involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125 		JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178 		JBrowse link
G Pdgfra platelet derived growth factor receptor, alpha polypeptide involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:75,311,988...75,358,867
Ensembl chr 5:75,312,953...75,358,876 		JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 acts_upstream_of_or_within IMP (PMID:19855083) MGI PMID:19855083 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif 18 acts_upstream_of_or_within IMP
ISO		 (PMID:19218546) MGI PMID:19218546 GO_REF:0000008 NCBI chr 8:114,423,755...114,575,975
Ensembl chr 8:114,423,758...114,575,370 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase involved_in IMP (MGI:1202206|PMID:9501222) UniProt PMID:9501222 MGI:1202206 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179 		JBrowse link
G C1qtnf1 C1q and tumor necrosis factor related protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:118,319,187...118,342,608
Ensembl chr11:118,319,029...118,340,789 		JBrowse link
G Cd9 CD9 antigen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP (MGI:3835235|PMID:19008452) UniProt PMID:19008452 MGI:3835235 NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028 		JBrowse link
G Prkcd protein kinase C, delta involved_in IMP (MGI:3813784|PMID:16940418) UniProt PMID:16940418 MGI:3813784 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167 		JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:30,541,887...31,742,675
Ensembl chr19:30,541,889...31,742,433 		JBrowse link
G Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 involved_in IMP (MGI:4418017|PMID:19855083) BHF-UCL PMID:19855083 MGI:4418017 NCBI chr 1:79,772,038...79,836,382
Ensembl chr 1:79,771,914...79,838,897 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IGI (MGI:5905608|PMID:27430239) BHF-UCL PMID:27430239 MGI:5905608 NCBI chr 5:121,953,544...121,975,706
Ensembl chr 5:121,953,551...121,975,709 		JBrowse link
G Tmx1 thioredoxin-related transmembrane protein 1 involved_in IMP
ISO		 (MGI:6284734|PMID:30425049) UniProt
MGI		 PMID:30425049 GO_REF:0000119 MGI:4834177 MGI:6284734 NCBI chr12:70,499,928...70,514,398
Ensembl chr12:70,499,869...70,514,814 		JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within IMP (PMID:20585042) MGI PMID:20585042 NCBI chr 9:40,922,056...41,069,358
Ensembl chr 9:40,922,394...41,072,993 		JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:45,693,696...45,715,092
Ensembl chr 8:45,694,211...45,715,068 		JBrowse link
G F12 coagulation factor XII (Hageman factor) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr13:55,565,771...55,574,617
Ensembl chr13:55,565,771...55,574,606 		JBrowse link
G Klkb1 kallikrein B, plasma 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:45,719,725...45,747,872
Ensembl chr 8:45,719,726...45,747,896 		JBrowse link
G Plg plasminogen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:12,597,496...12,638,271
Ensembl chr17:12,597,495...12,638,272 		JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222 		JBrowse link
G Plau plasminogen activator, urokinase involved_in NAS (MGI:6869956|PMID:3920216) ComplexPortal PMID:3920216 MGI:6869956 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453 		JBrowse link
G Plaur plasminogen activator, urokinase receptor involved_in NAS (MGI:6869956|PMID:3920216) ComplexPortal PMID:3920216 MGI:6869956 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    negative regulation of biological process 5939
      negative regulation of hemostasis 48
        negative regulation of blood coagulation 47
          fibrinolysis + 22
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 16
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 28573
    biological regulation 13118
      regulation of biological process 12727
        regulation of response to stimulus 4381
          regulation of response to stress 1535
            regulation of response to wounding 188
              regulation of wound healing 140
                regulation of blood coagulation 67
                  negative regulation of blood coagulation 47
                    fibrinolysis + 22
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 16
                    positive regulation of fibrinolysis 4
paths to the root