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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation



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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADTRP androgen dependent TFPI regulating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:11,550,584...11,648,755
Ensembl chr 6:11,829,782...11,895,656
JBrowse link
G ANXA5 annexin A5 ISO RGD PMID:20684318 RGD:7241850 NCBI chr 4:113,868,218...113,897,243
Ensembl chr 4:125,006,038...125,034,972
JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483
JBrowse link
G CD34 CD34 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:183,459,028...183,489,583
Ensembl chr 1:188,272,551...188,297,384
JBrowse link
G KNG1 kininogen 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149
JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa involved_in
acts_upstream_of_or_within
ISO (PMID:25651845)
(MGI:1306904|PMID:9788960)
(MGI:1261704|PMID:9616155)
RGD
ComplexPortal
MGI
PMID:1440533 PMID:9616155 PMID:9788960 PMID:25651845 MGI:1261704 MGI:1306904 RGD:11100042 NCBI chr2B:32,846,899...32,859,060
Ensembl chr2B:128,083,794...128,094,625
JBrowse link
G PROS1 protein S involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:90,934,641...91,039,059
Ensembl chr 3:97,615,734...97,718,756
JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040
JBrowse link
G TFPI tissue factor pathway inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:74,744,154...74,834,338
Ensembl chr2B:192,541,881...192,581,384
JBrowse link
G THBD thrombomodulin involved_in IEA InterPro GO_REF:0000002 NCBI chr20:22,992,341...22,996,415
Ensembl chr20:23,345,917...23,347,812
JBrowse link
G TSPAN8 tetraspanin 8 ISO RGD PMID:9531564 RGD:634231 NCBI chr12:68,653,209...68,686,565
Ensembl chr12:71,417,577...71,450,873
JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 acts_upstream_of_or_within ISO (MGI:3027337|PMID:14702107) MGI PMID:14702107 MGI:3027337 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250
JBrowse link
G CPB2 carboxypeptidase B2 involved_in ISO
IEA
RGD
InterPro
PMID:11848438 GO_REF:0000002 RGD:632532 NCBI chr13:26,926,788...26,979,767 JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157
JBrowse link
G FGA fibrinogen alpha chain involved_in ISO (PMID:16846481) UniProt PMID:16846481 NCBI chr 4:146,949,680...146,957,291 JBrowse link
G FGB fibrinogen beta chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766
JBrowse link
G FGG fibrinogen gamma chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237
JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) UniProt PMID:12855810 NCBI chr17:4,980,083...4,983,219 JBrowse link
G HRG histidine rich glycoprotein acts_upstream_of ISO (MGI:3789419|PMID:15869579) MGI PMID:15869579 MGI:3789419 NCBI chr 3:183,701,069...183,712,365
Ensembl chr 3:192,168,299...192,180,539
JBrowse link
G LOC100982214 plasminogen involved_in IEA Ensembl
UniProt
GO_REF:0000043 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777
JBrowse link
G PLAU plasminogen activator, urokinase acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:1277054|PMID:9733098) MGI
Ensembl
PMID:9733098 GO_REF:0000107 MGI:1277054 NCBI chr10:70,433,340...70,441,569
Ensembl chr10:73,105,895...73,113,136
JBrowse link
G PROS1 protein S involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:90,934,641...91,039,059
Ensembl chr 3:97,615,734...97,718,756
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483
JBrowse link
G CPB2 carboxypeptidase B2 ISO RGD PMID:17002650 RGD:2313647 NCBI chr13:26,926,788...26,979,767 JBrowse link
G HRG histidine rich glycoprotein acts_upstream_of_or_within ISO (MGI:3789419|PMID:15869579) MGI PMID:15869579 MGI:3789419 NCBI chr 3:183,701,069...183,712,365
Ensembl chr 3:192,168,299...192,180,539
JBrowse link
G LOC100982214 plasminogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777
JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450
JBrowse link
G SERPINF2 serpin family F member 2 involved_in ISO
IEA
RGD
Ensembl
InterPro
PMID:6506034 GO_REF:0000002 GO_REF:0000107 RGD:1625541 NCBI chr17:1,725,469...1,738,887
Ensembl chr17:1,618,549...1,631,570
JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170
JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490
JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:73,099,560...73,126,304
Ensembl chr17:78,644,531...78,669,386
JBrowse link
G GP5 glycoprotein V platelet acts_upstream_of_or_within ISO (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305) MGI PMID:10557321 PMID:11435305 MGI:1347746 MGI:2137180 NCBI chr 3:191,691,432...191,696,906
Ensembl chr 3:202,008,334...202,010,005
JBrowse link
G PDGFA platelet derived growth factor subunit A involved_in ISO (PMID:2538439) BHF-UCL PMID:2538439 NCBI chr 7:648,722...672,023 JBrowse link
G PDGFB platelet derived growth factor subunit B involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:20,127,223...20,148,407
Ensembl chr22:37,944,018...37,964,883
JBrowse link
G PDGFRA platelet derived growth factor receptor alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:69,639,081...69,709,870
Ensembl chr 4:76,199,382...76,271,097
JBrowse link
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4418017|PMID:19855083) MGI
Ensembl
PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:12742000 RGD:10047059 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420
JBrowse link
G ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif 18 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3848389|PMID:19218546)
(PMID:19218546)
MGI
Ensembl
PMID:19218546 GO_REF:0000107 MGI:3848389 NCBI chr16:57,857,112...58,011,181
Ensembl chr16:77,291,148...77,445,664
JBrowse link
G ADRB2 adrenoceptor beta 2 ISO RGD PMID:6140045 RGD:8548522 NCBI chr 5:144,259,756...144,398,421
Ensembl chr 5:150,267,554...150,315,892
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602
JBrowse link
G C1QTNF1 C1q and TNF related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:73,099,560...73,126,304
Ensembl chr17:78,644,531...78,669,386
JBrowse link
G CD9 CD9 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,327,783...6,366,083
Ensembl chr12:6,245,348...6,283,385
JBrowse link
G CEACAM1 CEA cell adhesion molecule 1 involved_in ISO (MGI:3835235|PMID:19008452) UniProt PMID:19008452 MGI:3835235 NCBI chr19:39,395,550...39,417,063
Ensembl chr19:47,989,430...48,008,739
JBrowse link
G FGG fibrinogen gamma chain ISO RGD PMID:22985603 RGD:11352706 NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237
JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:53,104,137...53,135,588
Ensembl chr 3:54,330,328...54,357,910
JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:47,642,312...48,935,188
Ensembl chr10:49,779,211...51,064,882
JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:20303752 RGD:10043327 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063
JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040
JBrowse link
G SH2B3 SH2B adaptor protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:108,977,344...109,024,029 JBrowse link
G UBASH3B ubiquitin associated and SH3 domain containing B acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:4838721|PMID:20585042) MGI
Ensembl
PMID:20585042 GO_REF:0000107 MGI:4838721 NCBI chr11:117,489,411...117,647,719
Ensembl chr11:121,410,545...121,563,133
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:178,436,865...178,459,568
Ensembl chr 4:190,643,733...190,666,512
JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485
JBrowse link
G KLKB1 kallikrein B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:178,398,359...178,429,448
Ensembl chr 4:190,604,901...190,636,300
JBrowse link
G LOC100982214 plasminogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOH apolipoprotein H involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:60,154,389...60,171,762
Ensembl chr17:65,365,250...65,382,483
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15327
    negative regulation of biological process 5263
      negative regulation of hemostasis 45
        negative regulation of blood coagulation 44
          fibrinolysis + 18
          negative regulation of blood coagulation in another organism + 0
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 19
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 15327
    biological regulation 10949
      regulation of biological process 10356
        regulation of response to stimulus 3654
          regulation of response to stress 1321
            regulation of response to wounding 171
              regulation of wound healing 129
                regulation of blood coagulation 64
                  negative regulation of blood coagulation 44
                    fibrinolysis + 18
                    negative regulation of blood coagulation in another organism + 0
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 19
                    positive regulation of fibrinolysis 4
paths to the root