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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation


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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in IEA
ISO
GO_REF:0000107
(PMID:21868574)
Ensembl
RGD
PMID:21868574 GO_REF:0000107 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Anxa5 annexin A5 IDA RGD PMID:20684318 RGD:7241850 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) RGD PMID:8995232 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:4052628)
GO_REF:0000107
RGD
Ensembl
PMID:4052628 GO_REF:0000107 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Cd34 CD34 molecule involved_in ISO
ISS
(PMID:17505307)
GO_REF:0000024
RGD
UniProt
PMID:17505307 GO_REF:0000024 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Kng1 kininogen 1 involved_in IBA
IEA
PMID:21873635
GO_REF:0000107
Ensembl PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr11:81,421,672...81,444,466
Ensembl chr11:81,421,676...81,444,621
JBrowse link
G Kng2 kininogen 2 involved_in ISO
IBA
(PMID:11970955)
PMID:21873635
RGD PMID:11970955, PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kng2l1 kininogen 2-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537
G Proc protein C, inactivator of coagulation factors Va and VIIIa acts_upstream_of_or_within
involved_in
IDA
ISO
IBA
MGI:2183063 (MGI:1261704|PMID:9616155), (MGI:1306904|PMID:9788960)
PMID:21873635
RGD PMID:9616155 PMID:9788960, PMID:1440533, PMID:21873635, PMID:21873635 MGI:1261704 MGI:1306904, RGD:11100042, RGD:13792537, RGD:13792537 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Serpine2 serpin family E member 2 involved_in ISO
IDA
(PMID:17379830) RGD PMID:17379830, PMID:17379830, PMID:17379830 RGD:8553298, RGD:8553298 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr 3:71,852,738...71,902,127
Ensembl chr 3:71,852,744...71,893,618
JBrowse link
G Thbd thrombomodulin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:142,748,673...142,752,325
Ensembl chr 3:142,748,674...142,752,325
JBrowse link
G Tspan8 tetraspanin 8 IDA RGD PMID:9531564 RGD:634231 NCBI chr 7:58,814,805...58,847,564
Ensembl chr 7:58,814,805...58,847,563
JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 acts_upstream_of_or_within ISO MGI:3028929 (MGI:3027337|PMID:14702107) RGD PMID:14702107 MGI:3027337 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:11848438, PMID:21873635, PMID:21873635 RGD:632532, RGD:13792537, RGD:13792537 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G F2 coagulation factor II involved_in IEA
ISO
GO_REF:0000107
(PMID:12855810)
Ensembl
RGD
PMID:12855810 GO_REF:0000107 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IEA
IBA
(PMID:16846481)
GO_REF:0000107
PMID:21873635
RGD
Ensembl
PMID:16846481, PMID:21873635, PMID:21873635 GO_REF:0000107, RGD:13792537, RGD:13792537 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Hrg histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plau plasminogen activator, urokinase acts_upstream_of_or_within
involved_in
IEA
ISO
IBA
GO_REF:0000107
(MGI:1277054|PMID:9733098)
PMID:21873635
Ensembl
RGD
PMID:9733098, PMID:21873635, PMID:21873635 GO_REF:0000107 MGI:1277054, RGD:13792537, RGD:13792537 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Plg plasminogen involved_in IEA
ISO
GO_REF:0000104
(PMID:14688145), (PMID:17307854), (PMID:22025510)
UniProt
RGD
PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:72,161,230...72,171,109
Ensembl chr 3:72,161,189...72,171,078
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:14726399)
GO_REF:0000107
RGD
Ensembl
PMID:14726399 GO_REF:0000107 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:57,290,849...57,339,762
Ensembl chr15:57,290,849...57,339,760
JBrowse link
G Hrg histidine-rich glycoprotein acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3789962 (MGI:3789419|PMID:15869579)
PMID:21873635
RGD PMID:15869579, PMID:21873635, PMID:21873635 MGI:3789419, RGD:13792537, RGD:13792537 NCBI chr11:81,621,274...81,639,938
Ensembl chr11:81,621,283...81,639,952
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 Ensembl chr11:81,621,283...81,639,952 JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:2503541)
GO_REF:0000107
RGD
Ensembl
PMID:2503541 GO_REF:0000107 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO
(PMID:134998) RGD PMID:134998, PMID:6506034 RGD:1625541 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in ISO
IEA
(PMID:8995232)
GO_REF:0000107
RGD
Ensembl
PMID:8995232 GO_REF:0000107 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162
JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305) RGD PMID:10557321 PMID:11435305 MGI:1347746 MGI:2137180 NCBI chr11:73,015,380...73,017,570 JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
IEA
ISS
(PMID:8188664)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:35,527,926...35,581,130
Ensembl chr14:35,527,927...35,581,031
JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (MGI:4418017|PMID:19855083) RGD PMID:19855083 MGI:4418017 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within
involved_in
ISO (PMID:19218546)
(MGI:3848389|PMID:19218546)
RGD PMID:19218546 MGI:3848389 NCBI chr19:46,005,055...46,167,912
Ensembl chr19:46,005,277...46,101,250
JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:6140045 RGD:8548522 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO
GO_REF:0000024
(MGI:1202206|PMID:9501222)
UniProt
RGD
PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:56,851,734...56,864,049
Ensembl chr10:56,851,734...56,864,005
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:16195328)
Ensembl
RGD
PMID:16195328 GO_REF:0000107 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162
JBrowse link
G Cd9 CD9 molecule involved_in ISO
ISS
(PMID:18541721)
GO_REF:0000024
RGD
UniProt
PMID:18541721 GO_REF:0000024 NCBI chr 4:157,977,163...158,010,091
Ensembl chr 4:157,977,162...158,010,166
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3835235|PMID:19008452)
UniProt
RGD
PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Fgg fibrinogen gamma chain IDA RGD PMID:22985603 RGD:11352706 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Prkcd protein kinase C, delta involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3813784|PMID:16940418)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:16940418 GO_REF:0000024 GO_REF:0000107 MGI:3813784 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:20303752 RGD:10043327 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4418017|PMID:19855083)
Ensembl
RGD
PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P35951 (MGI:5905608|PMID:27430239)
Ensembl
RGD
PMID:27430239 GO_REF:0000107 MGI:5905608 NCBI chr12:40,261,990...40,265,757
Ensembl chr12:40,244,081...40,265,757
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042) RGD PMID:20585042 MGI:4838721 NCBI chr 8:45,224,053...45,375,450
Ensembl chr 8:45,223,992...45,375,435
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:50,179,458...50,201,644
Ensembl chr16:50,179,458...50,201,698
JBrowse link
G F12 coagulation factor XII involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr17:9,736,577...9,744,420
Ensembl chr17:9,736,577...9,744,420
JBrowse link
G Klkb1 kallikrein B1 involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:50,151,127...50,175,407
Ensembl chr16:50,152,008...50,175,458
JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    negative regulation of biological process 5713
      negative regulation of hemostasis 49
        negative regulation of blood coagulation 48
          fibrinolysis + 20
          negative regulation of blood coagulation in other organism + 0
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 19
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 20082
    biological regulation 13906
      regulation of biological process 13141
        regulation of response to stimulus 3981
          regulation of response to stress 1296
            regulation of response to wounding 174
              regulation of wound healing 131
                regulation of blood coagulation 66
                  negative regulation of blood coagulation 48
                    fibrinolysis + 20
                    negative regulation of blood coagulation in other organism + 0
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 19
                    positive regulation of fibrinolysis 4
paths to the root