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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood coagulation
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Accession:GO:0030195 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
Synonyms:exact_synonym: down regulation of blood coagulation;   downregulation of blood coagulation
 narrow_synonym: inhibition of blood coagulation



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negative regulation of blood coagulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adtrp androgen-dependent TFPI-regulating protein involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Anxa5 annexin A5 IDA RGD PMID:20684318 RGD:7241850 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Apoe apolipoprotein E involved_in ISO (PMID:8995232) RGD PMID:8995232 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoh apolipoprotein H involved_in IEA
ISO
GO_REF:0000107
(PMID:4052628)
Ensembl
RGD
PMID:4052628 GO_REF:0000107 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Cd34 CD34 molecule involved_in ISO
ISS
(PMID:17505307)
GO_REF:0000024
RGD
UniProt
PMID:17505307 GO_REF:0000024 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832
JBrowse link
G Kng1 kininogen 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
JBrowse link
G Kng2 kininogen 2 involved_in ISO
IBA
(PMID:11970955)
PMID:21873635
RGD PMID:11970955 PMID:21873635 RGD:13792537 NCBI chr11:77,913,876...77,936,247
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Kng2l1 kininogen 2-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:77,978,795...78,002,976
Ensembl chr11:77,909,612...78,002,971
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa involved_in
acts_upstream_of_or_within
IDA
ISO
IBA
(PMID:25651845)
MGI:2183063 (MGI:1261704|PMID:9616155), (MGI:1306904|PMID:9788960)
PMID:21873635
RGD PMID:9616155 PMID:9788960 PMID:25651845 PMID:1440533 PMID:21873635 MGI:1261704 MGI:1306904, RGD:11100042, RGD:13792537 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Serpine2 serpin family E member 2 involved_in IDA
ISO
PMID:17379830
(PMID:17379830)
RGD PMID:17379830 PMID:17379830 RGD:8553298 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Tfpi tissue factor pathway inhibitor involved_in ISO (PMID:21868574) RGD PMID:21868574 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880
JBrowse link
G Thbd thrombomodulin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Tspan8 tetraspanin 8 IDA RGD PMID:9531564 RGD:634231 NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356
JBrowse link
fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 acts_upstream_of_or_within ISO MGI:3028929 (MGI:3027337|PMID:14702107) RGD PMID:14702107 MGI:3027337 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Cpb2 carboxypeptidase B2 involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:11848438 PMID:21873635 RGD:632532, RGD:13792537 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G F12 coagulation factor XII involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G F2 coagulation factor II involved_in ISO
IEA
(PMID:12855810)
GO_REF:0000107
RGD
Ensembl
PMID:12855810 GO_REF:0000107 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G Fga fibrinogen alpha chain involved_in IBA
ISO
PMID:21873635
(PMID:16846481)
RGD PMID:16846481 PMID:21873635 RGD:13792537 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO (PMID:16846481) RGD PMID:16846481 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO (PMID:12855810) RGD PMID:12855810 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Hrg histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Klkb1 kallikrein B1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Plau plasminogen activator, urokinase involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
(MGI:1277054|PMID:9733098)
GO_REF:0000107
RGD
Ensembl
PMID:9733098 PMID:21873635 GO_REF:0000107 MGI:1277054, RGD:13792537 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Plg plasminogen involved_in IEA
ISO
GO_REF:0000104
(PMID:14688145), (PMID:17307854), (PMID:22025510)
UniProt
RGD
PMID:14688145 PMID:17307854 PMID:22025510 GO_REF:0000104 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Pros1 protein S involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286
JBrowse link
G Serping1 serpin family G member 1 involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034
JBrowse link
negative regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoh apolipoprotein H involved_in ISO
IEA
(PMID:14726399)
GO_REF:0000107
RGD
Ensembl
PMID:14726399 GO_REF:0000107 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Cpb2 carboxypeptidase B2 IDA RGD PMID:17002650 RGD:2313647 NCBI chr15:50,557,722...50,606,569
Ensembl chr15:50,557,717...50,606,556
JBrowse link
G Hrg histidine-rich glycoprotein involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3789962 (MGI:3789419|PMID:15869579)
RGD PMID:15869579 PMID:21873635 MGI:3789419, RGD:13792537 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Plg plasminogen involved_in ISO (PMID:14726399) RGD PMID:14726399 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Serpine1 serpin family E member 1 involved_in ISO
IEA
(PMID:2503541)
GO_REF:0000107
RGD
Ensembl
PMID:2503541 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinf2 serpin family F member 2 involved_in IMP
ISO
(PMID:134998) RGD PMID:134998 PMID:6506034 RGD:1625541 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:6438154) RGD PMID:6438154 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
(PMID:8995232)
Ensembl
RGD
PMID:8995232 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305) RGD PMID:10557321 PMID:11435305 MGI:1347746 MGI:2137180 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
ISS
(PMID:2538439)
GO_REF:0000024
RGD
UniProt
PMID:2538439 GO_REF:0000024 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:8188664)
UniProt
Ensembl
RGD
PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (MGI:4418017|PMID:19855083) RGD PMID:19855083 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (MGI:3848389|PMID:19218546)
(PMID:19218546)
RGD PMID:19218546 MGI:3848389 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781
JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:6140045 RGD:8548522 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO
GO_REF:0000024
(MGI:1202206|PMID:9501222)
UniProt
RGD
PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO
IEA
(PMID:16195328)
GO_REF:0000107
RGD
Ensembl
PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:18541721)
UniProt
RGD
PMID:18541721 GO_REF:0000024 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3835235|PMID:19008452)
UniProt
RGD
PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Fgg fibrinogen gamma chain IDA RGD PMID:22985603 RGD:11352706 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
GO_REF:0000024
(MGI:3813784|PMID:16940418)
UniProt
RGD
PMID:16940418 GO_REF:0000024 MGI:3813784 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:20303752 RGD:10043327 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4418017|PMID:19855083)
Ensembl
RGD
PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P35951 (MGI:5905608|PMID:27430239)
Ensembl
RGD
PMID:27430239 GO_REF:0000107 MGI:5905608 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042) RGD PMID:20585042 MGI:4838721 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
positive regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F11 coagulation factor XI involved_in ISO (PMID:89876) RGD PMID:89876 NCBI chr16:46,986,107...47,009,015
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F12 coagulation factor XII involved_in IEA
ISO
GO_REF:0000107
(PMID:89876)
Ensembl
RGD
PMID:89876 GO_REF:0000107 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Klkb1 kallikrein B1 involved_in ISO
IEA
(PMID:89876)
GO_REF:0000107
RGD
Ensembl
PMID:89876 GO_REF:0000107 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053
JBrowse link
G Plg plasminogen involved_in ISO (PMID:26667841), (PMID:6438154) RGD PMID:6438154 PMID:26667841 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
regulation of fibrinolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 TAS RGD PMID:11739291 RGD:1578383 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Apoh apolipoprotein H involved_in ISO (PMID:16480936) RGD PMID:16480936 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    negative regulation of biological process 5703
      negative regulation of hemostasis 49
        negative regulation of blood coagulation 48
          fibrinolysis + 20
          negative regulation of blood coagulation in another organism + 0
          negative regulation of blood coagulation, common pathway 0
          negative regulation of blood coagulation, extrinsic pathway 0
          negative regulation of blood coagulation, intrinsic pathway 0
          negative regulation of platelet activation + 19
          positive regulation of fibrinolysis 4
Path 2
Term Annotations click to browse term
  biological_process 19512
    biological regulation 13616
      regulation of biological process 12887
        regulation of response to stimulus 4067
          regulation of response to stress 1387
            regulation of response to wounding 178
              regulation of wound healing 135
                regulation of blood coagulation 68
                  negative regulation of blood coagulation 48
                    fibrinolysis + 20
                    negative regulation of blood coagulation in another organism + 0
                    negative regulation of blood coagulation, common pathway 0
                    negative regulation of blood coagulation, extrinsic pathway 0
                    negative regulation of blood coagulation, intrinsic pathway 0
                    negative regulation of platelet activation + 19
                    positive regulation of fibrinolysis 4
paths to the root