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Term:melatonin biosynthetic process
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Accession:GO:0030187 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
Synonyms:exact_synonym: melatonin anabolism;   melatonin biosynthesis;   melatonin formation;   melatonin synthesis

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melatonin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aanat aralkylamine N-acetyltransferase ISO (PMID:11313340) UniProtKB PMID:11313340 NCBI chrNW_004955506:5,828,666...5,834,812
Ensembl chrNW_004955506:5,828,659...5,834,812
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G Asmt acetylserotonin O-methyltransferase ISO (PMID:22775292)
PMID:3941912, PMID:8930356, PMID:12198599, PMID:20308563, PMID:22775292 MGI:4442290, MGI:56619, RGD:1299464, RGD:1359073 NCBI chrNW_004955499:1,131,637...1,151,861
Ensembl chrNW_004955499:1,131,588...1,152,802
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11892
    metabolic process 7608
      biosynthetic process 3890
        hormone biosynthetic process 48
          melatonin biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 11892
    biological regulation 8725
      regulation of biological quality 3366
        regulation of hormone levels 493
          hormone metabolic process 152
            cellular hormone metabolic process 73
              melatonin metabolic process 3
                melatonin biosynthetic process 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.