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Term:melatonin biosynthetic process
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Accession:GO:0030187 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
Synonyms:exact_synonym: melatonin anabolism;   melatonin biosynthesis;   melatonin formation;   melatonin synthesis

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melatonin biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AANAT aralkylamine N-acetyltransferase ISO (PMID:11313340) UniProtKB PMID:11313340 NCBI chr17:70,401,103...70,418,551
Ensembl chr17:75,951,915...75,967,411
JBrowse link
G ASMT acetylserotonin O-methyltransferase ISO (PMID:22775292)
PMID:3941912, PMID:8930356, PMID:12198599, PMID:20308563, PMID:22775292 MGI:4442290, MGI:56619, RGD:1299464, RGD:1359073 Ensembl chr  X:1,749,371...1,772,916 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12566
    metabolic process 7977
      biosynthetic process 4032
        hormone biosynthetic process 52
          melatonin biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 12566
    biological regulation 9172
      regulation of biological quality 3507
        regulation of hormone levels 520
          hormone metabolic process 172
            cellular hormone metabolic process 88
              melatonin metabolic process 3
                melatonin biosynthetic process 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.