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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of Wnt signaling pathway
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Accession:GO:0030177 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
Synonyms:exact_synonym: positive regulation of Wnt receptor signaling pathway;   positive regulation of Wnt receptor signalling pathway;   positive regulation of Wnt-activated signaling pathway;   positive regulation of frizzled signaling pathway;   positive regulation of frizzled signalling pathway;   up regulation of Wnt receptor signaling pathway;   up regulation of frizzled signaling pathway;   upregulation of Wnt receptor signaling pathway;   upregulation of frizzled signaling pathway
 narrow_synonym: activation of Wnt receptor signaling pathway;   activation of frizzled signaling pathway;   stimulation of Wnt receptor signaling pathway;   stimulation of frizzled signaling pathway
 alt_id: GO:0045811


show annotations for term's descendants           Sort by:
positive regulation of Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:36,271,154...36,300,240
Ensembl chr  X:36,271,222...36,304,181 		JBrowse link
G ATP6V0C ATPase H+ transporting V0 subunit c involved_in ISO (PMID:20093472) UniProt PMID:20093472 NCBI chr 3:39,532,707...39,538,704 JBrowse link
G ATP6V1C2 ATPase H+ transporting V1 subunit C2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:125,774,259...125,825,752
Ensembl chr 3:125,775,099...125,825,244 		JBrowse link
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14627707) Ensembl
MGI		 PMID:14627707 GO_REF:0000107 NCBI chr17:15,750,487...15,762,982
Ensembl chr17:15,749,835...15,761,195 		JBrowse link
G CCN4 cellular communication network factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,078,163...8,110,906
Ensembl chr 4:8,079,755...8,110,700 		JBrowse link
G CDC73 cell division cycle 73 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:575,075...667,618
Ensembl chr10:575,075...667,432 		JBrowse link
G CRBN cereblon involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:59,733,503...59,757,776
Ensembl chr13:59,730,639...59,757,860 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISO (MGI:5705223|PMID:17027228) ParkinsonsUK-UCL PMID:17027228 MGI:5705223 NCBI chr12:768,856...794,495
Ensembl chr12:768,865...796,595 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:9,594,461...9,620,483
Ensembl chr 5:9,594,934...9,620,476 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:12700239) UniProt PMID:12700239 NCBI chr17:34,692,960...34,748,067 JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:187,719,391...187,729,568
Ensembl chr 1:187,719,290...187,729,422 		JBrowse link
G DEPDC1B DEP domain containing 1B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:39,466,496...39,558,750
Ensembl chr16:39,466,497...39,557,840 		JBrowse link
G DISC1 DISC1 scaffold protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:58,606,441...58,963,954
Ensembl chr14:58,606,464...58,963,563 		JBrowse link
G DIXDC1 DIX domain containing 1 involved_in ISO (MGI:4821185|PMID:20624590) DFLAT PMID:20624590 MGI:4821185 NCBI chr 9:39,666,454...39,734,909 JBrowse link
G ELOVL7 ELOVL fatty acid elongase 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:39,588,122...39,680,273
Ensembl chr16:39,588,129...39,680,173 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17560563) Ensembl
MGI		 PMID:17560563 GO_REF:0000107 NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:16989802) UniProt
MGI		 PMID:16989802 GO_REF:0000024 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FZD4 frizzled class receptor 4 involved_in ISO (PMID:11401527) BHF-UCL PMID:11401527 NCBI chr 9:20,714,995...20,721,460
Ensembl chr 9:20,717,344...20,721,460 		JBrowse link
G HHEX hematopoietically expressed homeobox involved_in ISO (MGI:3777521|PMID:16936074) UniProt PMID:16936074 MGI:3777521 NCBI chr14:104,194,424...104,199,684
Ensembl chr14:104,194,343...104,200,219 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:221,015,042...221,218,875
Ensembl chr 1:221,015,046...221,078,245 		JBrowse link
G LEF1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30659184) Ensembl
MGI		 PMID:30659184 GO_REF:0000107 NCBI chr 8:113,824,511...113,944,078
Ensembl chr 8:113,825,161...113,944,070 		JBrowse link
G LGR6 leucine rich repeat containing G protein-coupled receptor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,358,946...24,454,430
Ensembl chr10:24,359,774...24,454,428 		JBrowse link
G MACF1 microtubule actin crosslinking factor 1 involved_in ISO (MGI:3640889|PMID:16815997) UniProt PMID:16815997 MGI:3640889 RGD:8553932 NCBI chr 6:94,960,385...95,318,126
Ensembl chr 6:95,153,005...95,301,618 		JBrowse link
G MBD2 methyl-CpG binding domain protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18644872) Ensembl
MGI		 PMID:18644872 GO_REF:0000107 NCBI chr 1:103,683,077...103,768,372
Ensembl chr 1:103,735,192...103,752,402 		JBrowse link
G PBXIP1 PBX homeobox interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:94,837,365...94,847,652
Ensembl chr 4:94,832,270...94,847,648 		JBrowse link
G RSPO1 R-spondin 1 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 6:93,664,839...93,690,328
Ensembl chr 6:93,665,121...93,685,197 		JBrowse link
G RSPO2 R-spondin 2 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 4:29,415,774...29,577,890
Ensembl chr 4:29,414,752...29,579,674 		JBrowse link
G RSPO3 R-spondin 3 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr 1:35,985,985...36,066,432
Ensembl chr 1:35,984,950...36,067,077 		JBrowse link
G RSPO4 R-spondin 4 involved_in IEA Ensembl
UniProt		 GO_REF:0000107 GO_REF:0000117 NCBI chr17:34,268,702...34,310,073
Ensembl chr17:34,268,612...34,309,991 		JBrowse link
G SALL1 spalt like transcription factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,731,666...33,748,698
Ensembl chr 6:33,732,025...33,748,704 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11520664) Ensembl
MGI		 PMID:11520664 GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:69,717,175...69,810,301
Ensembl chr 2:69,662,238...69,810,295 		JBrowse link
G SPIN1 spindlin 1 involved_in ISO (PMID:24589551), (PMID:29061846) UniProt PMID:24589551 PMID:29061846 NCBI chr14:227,219...291,420
Ensembl chr14:227,209...294,826 		JBrowse link
G SULF1 sulfatase 1 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:65,595,947...65,778,889
Ensembl chr 4:65,595,951...65,778,884 		JBrowse link
G SULF2 sulfatase 2 involved_in IEA UniProt
TreeGrafter
Ensembl		 GO_REF:0000104 GO_REF:0000107 GO_REF:0000118 NCBI chr17:49,663,721...49,805,118
Ensembl chr17:49,663,731...49,804,577 		JBrowse link
G TERT telomerase reverse transcriptase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:79,258,591...79,276,421
Ensembl chr16:79,258,591...79,276,421 		JBrowse link
G TLR2 toll like receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,993...75,428,330 		JBrowse link
G TMEM132A transmembrane protein 132A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:33324648) Ensembl
MGI		 PMID:33324648 GO_REF:0000107 NCBI chr 2:10,814,305...10,827,851
Ensembl chr 2:10,814,307...10,824,894 		JBrowse link
G TNFAIP3 TNF alpha induced protein 3 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:26,474,158...26,489,771
Ensembl chr 1:26,473,938...26,489,822 		JBrowse link
G WLS Wnt ligand secretion mediator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:144,242,639...144,529,659
Ensembl chr 6:144,399,926...144,555,880 		JBrowse link
G WNT3 Wnt family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:17,627,291...17,681,197
Ensembl chr12:17,628,726...17,681,026 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within ISO (PMID:17644613) MGI PMID:17644613 NCBI chr15:7,498,879...7,631,347
Ensembl chr15:7,499,026...7,632,655 		JBrowse link
G ZRANB1 zinc finger RANBP2-type containing 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:134,253,927...134,327,835
Ensembl chr14:134,254,000...134,329,064 		JBrowse link
positive regulation of canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRA2 adhesion G protein-coupled receptor A2 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:48,572,953...48,611,034
Ensembl chr15:48,573,197...48,610,668 		JBrowse link
G ADNP activity dependent neuroprotector homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:52,316,388...52,350,732
Ensembl chr17:52,317,913...52,332,079 		JBrowse link
G AMER1 APC membrane recruitment protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:50,842,049...50,864,105
Ensembl chr  X:50,844,683...50,864,032 		JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in ISO (MGI:5437152|PMID:22611086), (MGI:5553223|PMID:23525013) UniProt PMID:22611086 PMID:23525013 MGI:5437152 MGI:5553223 NCBI chr 2:45,895,637...46,025,174
Ensembl chr 2:45,895,289...45,988,570 		JBrowse link
G ASPM assembly factor for spindle microtubules acts_upstream_of_or_within ISO (PMID:21937711) MGI PMID:21937711 NCBI chr10:19,971,516...20,039,680
Ensembl chr10:19,975,192...20,039,623 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,271,154...36,300,240
Ensembl chr  X:36,271,222...36,304,181 		JBrowse link
G BAMBI BMP and activin membrane bound inhibitor involved_in IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr10:40,053,368...40,058,590
Ensembl chr10:40,053,355...40,060,319 		JBrowse link
G CAPRIN2 caprin family member 2 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 5:43,042,910...43,087,644
Ensembl chr 5:43,044,266...43,087,748 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,860,052...6,874,334
Ensembl chr14:6,859,664...6,874,327 		JBrowse link
G CDH3 cadherin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,190,971...18,236,184
Ensembl chr 6:18,191,664...18,235,862 		JBrowse link
G COL1A1 collagen type I alpha 1 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:768,856...794,495
Ensembl chr12:768,865...796,595 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:17606995)
(PMID:14966280)		 Ensembl
MGI
TreeGrafter
GO_Central		 PMID:14966280 PMID:17606995 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:9,594,461...9,620,483
Ensembl chr 5:9,594,934...9,620,476 		JBrowse link
G CSNK1G1 casein kinase 1 gamma 1 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:107,690,049...107,884,054
Ensembl chr 1:107,690,065...107,884,045 		JBrowse link
G CSNK1G2 casein kinase 1 gamma 2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:76,573,979...76,609,631
Ensembl chr 2:76,573,987...76,609,384 		JBrowse link
G CSNK1G3 casein kinase 1 gamma 3 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 2:127,013,736...127,129,547
Ensembl chr 2:127,017,026...127,129,543 		JBrowse link
G CTDNEP1 CTD nuclear envelope phosphatase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr12:52,599,226...52,606,059 JBrowse link
G DAAM2 dishevelled associated activator of morphogenesis 2 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:35,127,245...35,285,933
Ensembl chr 7:35,159,888...35,285,941 		JBrowse link
G DACT1 dishevelled binding antagonist of beta catenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:187,719,391...187,729,568
Ensembl chr 1:187,719,290...187,729,422 		JBrowse link
G DAPK3 death associated protein kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,758,962...74,776,355
Ensembl chr 2:74,759,004...74,775,330 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,988,031...37,005,496
Ensembl chr  X:36,988,031...37,018,202 		JBrowse link
G DKK2 dickkopf WNT signaling pathway inhibitor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:114,862,056...114,974,327
Ensembl chr 8:114,862,247...114,974,304 		JBrowse link
G DLX5 distal-less homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17804636) Ensembl
MGI		 PMID:17804636 GO_REF:0000107 NCBI chr 9:76,639,915...76,643,689
Ensembl chr 9:76,639,561...76,643,884 		JBrowse link
G EDA ectodysplasin A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19619491) Ensembl
MGI		 PMID:19619491 GO_REF:0000107 NCBI chr  X:55,770,958...56,103,296
Ensembl chr  X:55,771,041...56,103,265 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046 		JBrowse link
G EGFR epidermal growth factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:139,302,410...139,474,632
Ensembl chr 9:139,300,022...139,475,589 		JBrowse link
G FAM53B family with sequence similarity 53 member B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:134,002,226...134,135,397
Ensembl chr14:134,002,228...134,082,462 		JBrowse link
G FGF10 fibroblast growth factor 10 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:16720875) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:16720875 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr16:28,695,465...28,779,953
Ensembl chr16:28,695,470...28,777,509 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:16858399) MGI PMID:16858399 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916 		JBrowse link
G FGF9 fibroblast growth factor 9 acts_upstream_of_or_within ISO (PMID:18533146) MGI PMID:18533146 NCBI chr11:1,554,648...1,581,938
Ensembl chr11:1,554,763...1,582,408 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:16720875)
(PMID:18533146)		 UniProt
MGI		 PMID:16720875 PMID:18533146 GO_REF:0000024 NCBI chr14:131,183,095...131,285,001
Ensembl chr14:131,181,713...131,289,425 		JBrowse link
G FGFR3 fibroblast growth factor receptor 3 acts_upstream_of_or_within ISO (PMID:19407216) MGI PMID:19407216 NCBI chr 8:879,151...894,968
Ensembl chr 8:879,159...894,964 		JBrowse link
G FRAT1 FRAT regulator of WNT signaling pathway 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:108,739,239...108,741,953
Ensembl chr14:108,739,541...108,740,380 		JBrowse link
G FZD9 frizzled class receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,753,294...10,762,812
Ensembl chr 3:10,754,783...10,757,147 		JBrowse link
G GID8 GID complex subunit 8 homolog involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:62,174,222...62,181,107
Ensembl chr17:62,174,231...62,181,107 		JBrowse link
G GPC3 glypican 3 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:109,536,495...109,973,605
Ensembl chr  X:109,536,504...109,973,607 		JBrowse link
G GPC5 glypican 5 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr11:60,791,000...62,149,911
Ensembl chr11:60,791,363...62,147,239 		JBrowse link
G GPRC5B G protein-coupled receptor class C group 5 member B involved_in ISO (MGI:5543849|PMID:24089469) UniProt PMID:24089469 MGI:5543849 NCBI chr 3:25,870,369...25,896,113
Ensembl chr 3:25,870,403...25,896,106 		JBrowse link
G GSKIP GSK3B interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:117,586,742...117,607,575
Ensembl chr 7:117,586,764...117,607,564 		JBrowse link
G HHEX hematopoietically expressed homeobox involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:104,194,424...104,199,684
Ensembl chr14:104,194,343...104,200,219 		JBrowse link
G ILK integrin linked kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858 		JBrowse link
G ILKAP ILK associated serine/threonine phosphatase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:137,740,291...137,765,758
Ensembl chr15:137,740,292...137,765,784 		JBrowse link
G JRK Jrk helix-turn-helix protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:1,476,298...1,493,597
Ensembl chr 4:1,490,800...1,492,356 		JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:221,015,042...221,218,875
Ensembl chr 1:221,015,046...221,078,245 		JBrowse link
G LGR4 leucine rich repeat containing G protein-coupled receptor 4 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:32,871,837...32,979,150
Ensembl chr 2:32,871,871...32,979,148 		JBrowse link
G LGR5 leucine rich repeat containing G protein-coupled receptor 5 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:35,463,257...35,595,234
Ensembl chr 5:35,463,279...35,595,930 		JBrowse link
G LRRK1 leucine rich repeat kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:139,494,126...139,624,609
Ensembl chr 1:139,494,121...139,624,604 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G LYPD6 LY6/PLAUR domain containing 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr15:2,579,619...2,696,153
Ensembl chr15:2,579,622...2,696,160 		JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 ISO RGD PMID:20128690 RGD:150573713 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,872,131...35,946,987 		JBrowse link
G MIR183 microRNA mir-183 involved_in ISO (PMID:23538390) BHF-UCL PMID:23538390 NCBI chr18:18,982,269...18,982,338
Ensembl chr18:18,982,269...18,982,338 		JBrowse link
G MIR26A microRNA mir-26a involved_in ISO (PMID:22484120) ARUK-UCL PMID:22484120 NCBI chr 5:23,112,744...23,112,827
Ensembl chr 5:23,112,744...23,112,827 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691 		JBrowse link
G NLE1 notchless homolog 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23231322) Ensembl
MGI		 PMID:23231322 GO_REF:0000107 NCBI chr12:40,035,518...40,044,395
Ensembl chr12:40,035,547...40,044,397 		JBrowse link
G NRARP NOTCH regulated ankyrin repeat protein acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:19154719) MGI
GO_Central
Ensembl		 PMID:19154719 GO_REF:0000033 GO_REF:0000107
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:68,715,898...68,729,471
Ensembl chr 2:68,715,880...68,729,870 		JBrowse link
G PLEKHA4 pleckstrin homology domain containing A4 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:54,144,016...54,170,661
Ensembl chr 6:54,144,020...54,170,638 		JBrowse link
G POU5F1 POU class 5 homeobox 1 involved_in ISO (PMID:19736317) BHF-UCL PMID:19736317 NCBI chr 7:23,564,654...23,570,691 JBrowse link
G PPM1A protein phosphatase, Mg2+/Mn2+ dependent 1A involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:189,248,974...189,296,147
Ensembl chr 1:189,207,577...189,291,345 		JBrowse link
G PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:96,237,660...96,317,278
Ensembl chr 3:96,221,873...96,317,247 		JBrowse link
G PPM1L protein phosphatase, Mg2+/Mn2+ dependent 1L involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:100,442,445...100,759,968
Ensembl chr13:100,443,011...100,756,039 		JBrowse link
G PPM1N protein phosphatase, Mg2+/Mn2+ dependent 1N (putative) involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 6:51,865,061...51,871,146
Ensembl chr 6:51,865,955...51,869,939 		JBrowse link
G PPP2R3A protein phosphatase 2 regulatory subunit B''alpha involved_in ISO (PMID:16567647) BHF-UCL PMID:16567647 NCBI chr13:76,945,318...77,148,521
Ensembl chr13:76,945,395...77,147,072 		JBrowse link
G PRDM15 PR/SET domain 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:205,174,356...205,241,562
Ensembl chr13:205,173,517...205,241,490 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:88,540,261...88,548,593
Ensembl chr  X:88,540,376...88,548,560 		JBrowse link
G PTK7 protein tyrosine kinase 7 (inactive) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:38,135,675...38,205,662
Ensembl chr 7:38,135,655...38,205,655 		JBrowse link
G RBPJ recombination signal binding protein for immunoglobulin kappa J region involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22711842) Ensembl
MGI		 PMID:22711842 GO_REF:0000107 NCBI chr 8:19,933,035...20,166,746
Ensembl chr 8:19,922,779...20,166,754 		JBrowse link
G RECK reversion inducing cysteine rich protein with kazal motifs involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:236,821,243...236,898,280
Ensembl chr 1:236,821,414...236,898,276 		JBrowse link
G RNF146 ring finger protein 146 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:35,909,789...35,927,265
Ensembl chr 1:35,909,575...35,926,968 		JBrowse link
G RNF220 ring finger protein 220 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:166,666,140...166,910,728
Ensembl chr 6:166,666,138...166,910,646 		JBrowse link
G ROR2 receptor tyrosine kinase like orphan receptor 2 involved_in ISO (MGI:4835141|PMID:18215320) BHF-UCL PMID:18215320 MGI:4835141 NCBI chr14:2,803,840...3,035,384
Ensembl chr14:2,804,061...3,035,296 		JBrowse link
G RPS12 ribosomal protein S12 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:33273532) FlyBase
Ensembl		 PMID:33273532 GO_REF:0000107 NCBI chr 1:30,920,804...30,923,392
Ensembl chr 1:30,920,808...30,923,658 		JBrowse link
G RSPO1 R-spondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:93,664,839...93,690,328
Ensembl chr 6:93,665,121...93,685,197 		JBrowse link
G RSPO2 R-spondin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18256198)
(PMID:18256198), (PMID:19213727)		 Ensembl
MGI		 PMID:18256198 PMID:19213727 GO_REF:0000107 NCBI chr 4:29,415,774...29,577,890
Ensembl chr 4:29,414,752...29,579,674 		JBrowse link
G RSPO3 R-spondin 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18842812)
(PMID:16543246)		 Ensembl
MGI		 PMID:16543246 PMID:18842812 GO_REF:0000107 NCBI chr 1:35,985,985...36,066,432
Ensembl chr 1:35,984,950...36,067,077 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:72,196,219...72,246,514
Ensembl chr13:72,200,511...72,248,582 		JBrowse link
G SCEL sciellin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:49,651,589...49,777,777
Ensembl chr11:49,651,673...49,775,429 		JBrowse link
G SEMA5A semaphorin 5A involved_in ISO (MGI:5526935|PMID:19850054) UniProt PMID:19850054 MGI:5526935 NCBI chr16:72,796,453...73,335,974
Ensembl chr16:72,756,383...73,328,981 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18166153) Ensembl
MGI		 PMID:18166153 GO_REF:0000107 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G SFRP4 secreted frizzled related protein 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18166153) MGI
Ensembl		 PMID:18166153 GO_REF:0000107 NCBI chr 9:108,404,314...108,414,335
Ensembl chr 9:108,404,040...108,414,307 		JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO PMID:20097766 BHF-UCL PMID:20097766 RGD:11079190 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in ISS
IEA		 BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:16,886,834...16,895,488
Ensembl chr 7:16,891,319...16,892,752 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19920076) Ensembl
MGI		 PMID:19920076 GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G SULF2 sulfatase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23740243) Ensembl
MGI		 PMID:23740243 GO_REF:0000107 NCBI chr17:49,663,721...49,805,118
Ensembl chr17:49,663,731...49,804,577 		JBrowse link
G TBL1X transducin beta like 1 X-linked involved_in ISO (PMID:18193033) UniProt PMID:18193033 NCBI chr  X:5,994,324...6,238,843 JBrowse link
G TBL1XR1 TBL1X/Y related 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:115,312,444...115,488,228
Ensembl chr13:115,312,452...115,487,284 		JBrowse link
G TGFB1 transforming growth factor beta 1 involved_in
acts_upstream_of		 ISO (PMID:12893825), (PMID:15040835)
(PMID:25605017)		 CACAO
ARUK-UCL		 PMID:12893825 PMID:15040835 PMID:25605017 NCBI chr 6:49,332,169...49,348,642
Ensembl chr 6:49,332,173...49,349,046 		JBrowse link
G TMEM198 transmembrane protein 198 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:121,553,686...121,559,860
Ensembl chr15:121,553,694...121,559,869 		JBrowse link
G TMEM198B transmembrane protein 198B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 5:21,273,407...21,279,341 JBrowse link
G TMEM9 transmembrane protein 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:23,586,487...23,600,042
Ensembl chr10:23,586,491...23,607,530 		JBrowse link
G TNKS tankyrase involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:55,513,874...55,681,544
Ensembl chr15:55,514,248...55,681,505 		JBrowse link
G TNKS2 tankyrase 2 involved_in IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:103,396,424...103,461,830
Ensembl chr14:103,396,459...103,461,821 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,342,774...54,377,557
Ensembl chr 6:54,342,784...54,377,155 		JBrowse link
G TTC21B tetratricopeptide repeat domain 21B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27482817) Ensembl
MGI		 PMID:27482817 GO_REF:0000107 NCBI chr15:72,430,250...72,512,503
Ensembl chr15:72,430,726...72,512,491 		JBrowse link
G UBE2B ubiquitin conjugating enzyme E2 B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:136,652,764...136,667,213
Ensembl chr 2:136,652,785...136,667,949 		JBrowse link
G UBR5 ubiquitin protein ligase E3 component n-recognin 5 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:34,645,794...34,794,510
Ensembl chr 4:34,645,809...34,793,940 		JBrowse link
G USP34 ubiquitin specific peptidase 34 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:80,330,896...80,589,514
Ensembl chr 3:80,370,691...80,587,761 		JBrowse link
G USP47 ubiquitin specific peptidase 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:47,449,162...47,583,893
Ensembl chr 2:47,449,161...47,582,819 		JBrowse link
G USP8 ubiquitin specific peptidase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:121,306,031...121,376,154
Ensembl chr 1:121,306,032...121,413,223 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:235,854,532...235,869,712
Ensembl chr 1:235,851,206...235,869,634 		JBrowse link
G VPS35 VPS35 retromer complex component involved_in ISO (MGI:5693230|PMID:17239604) ParkinsonsUK-UCL PMID:17239604 MGI:5693230 NCBI chr 6:37,944,099...37,977,091
Ensembl chr 6:37,944,127...37,986,171 		JBrowse link
G WLS Wnt ligand secretion mediator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:144,242,639...144,529,659
Ensembl chr 6:144,399,926...144,555,880 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:68,000,792...68,142,533
Ensembl chr 5:68,000,905...68,140,755 		JBrowse link
G WNK2 WNK lysine deficient protein kinase 2 involved_in ISO (PMID:23797875) FlyBase PMID:23797875 NCBI chr 3:42,711,388...42,837,650
Ensembl chr 3:42,711,444...42,834,753 		JBrowse link
G WNT10B Wnt family member 10B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19723499) Ensembl
MGI		 PMID:19723499 GO_REF:0000107 NCBI chr 5:14,997,377...15,013,928
Ensembl chr 5:14,997,381...15,003,567 		JBrowse link
G WNT3A Wnt family member 3A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18155657), (PMID:23740243) Ensembl
MGI		 PMID:18155657 PMID:23740243 GO_REF:0000107 NCBI chr 2:51,153,978...51,203,678
Ensembl chr 2:51,153,970...51,202,176 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:101,399,374...101,440,021
Ensembl chr  X:101,399,812...101,440,013 		JBrowse link
G YAP1 Yes1 associated transcriptional regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17980593) Ensembl
MGI		 PMID:17980593 GO_REF:0000107 NCBI chr 9:32,811,629...32,924,926
Ensembl chr 9:32,811,416...32,925,603 		JBrowse link
G ZBED3 zinc finger BED-type containing 3 acts_upstream_of_or_within ISO (PMID:19141611) MGI PMID:19141611 NCBI chr 2:85,945,357...85,958,452 JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 involved_in ISO (PMID:30592286) DIBU PMID:30592286 NCBI chr15:7,498,879...7,631,347
Ensembl chr15:7,499,026...7,632,655 		JBrowse link
positive regulation of non-canonical Wnt signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSNK1D casein kinase 1 delta involved_in ISO (MGI:3707948|PMID:17244647) ParkinsonsUK-UCL PMID:17244647 MGI:3707948 NCBI chr12:768,856...794,495
Ensembl chr12:768,865...796,595 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:9,594,461...9,620,483
Ensembl chr 5:9,594,934...9,620,476 		JBrowse link
G NKD1 NKD inhibitor of WNT signaling pathway 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:34,223,888...34,319,584
Ensembl chr 6:34,223,884...34,319,528 		JBrowse link
G RSPO1 R-spondin 1 acts_upstream_of_or_within ISO (PMID:21991325) MGI PMID:21991325 NCBI chr 6:93,664,839...93,690,328
Ensembl chr 6:93,665,121...93,685,197 		JBrowse link
G RSPO3 R-spondin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:35,985,985...36,066,432
Ensembl chr 1:35,984,950...36,067,077 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:37,344,684...37,367,215
Ensembl chr13:37,344,699...37,367,207 		JBrowse link
positive regulation of Wnt signaling pathway, planar cell polarity pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20837657) Ensembl
MGI		 PMID:20837657 GO_REF:0000107 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,708 		JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (PMID:20837657) MGI PMID:20837657 NCBI chr 9:120,888,891...120,984,724
Ensembl chr 9:120,892,952...120,984,695 		JBrowse link
G ANKRD6 ankyrin repeat domain 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19591803) Ensembl
MGI		 PMID:19591803 GO_REF:0000107 NCBI chr 1:57,437,947...57,648,262
Ensembl chr 1:57,438,000...57,645,957 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122 		JBrowse link
G GPC3 glypican 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:15537637
(PMID:15537637)		 MGI
Ensembl		 PMID:15537637 GO_REF:0000107 RGD:8554067 NCBI chr  X:109,536,495...109,973,605
Ensembl chr  X:109,536,504...109,973,607 		JBrowse link
G MLLT3 MLLT3 super elongation complex subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19591803) MGI
Ensembl		 PMID:19591803 GO_REF:0000107 NCBI chr 1:202,317,458...202,604,308
Ensembl chr 1:202,318,929...202,607,058 		JBrowse link
G NKD1 NKD inhibitor of WNT signaling pathway 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:34,223,888...34,319,584
Ensembl chr 6:34,223,884...34,319,528 		JBrowse link
G PLEKHA4 pleckstrin homology domain containing A4 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:54,144,016...54,170,661
Ensembl chr 6:54,144,020...54,170,638 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17813
    cellular process 16883
      signal transduction 6956
        positive regulation of signal transduction 1669
          positive regulation of Wnt signaling pathway 147
            Wnt receptor recycling 0
            positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region 0
            positive regulation of canonical Wnt signaling pathway 111
            positive regulation of non-canonical Wnt signaling pathway + 14
Path 2
Term Annotations click to browse term
  biological_process 17813
    biological regulation 12832
      regulation of biological process 12482
        regulation of cellular process 12025
          signal transduction 6956
            cell surface receptor signaling pathway 2787
              Wnt signaling pathway 454
                regulation of Wnt signaling pathway 340
                  positive regulation of Wnt signaling pathway 147
                    Wnt receptor recycling 0
                    positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region 0
                    positive regulation of canonical Wnt signaling pathway 111
                    positive regulation of non-canonical Wnt signaling pathway + 14
paths to the root