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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-templated DNA replication initiation
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Accession:GO:0030174 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
Synonyms:exact_synonym: DNA replication licencing;   DNA replication licensing;   regulation of DNA-dependent DNA replication initiation
 broad_synonym: regulation of DNA replication initiation



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regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA
(PMID:11125146)
GO_REF:0000033
(MGI:2388867|PMID:12192004)
RGD
GO_Central
PMID:11125146 PMID:12192004 GO_REF:0000033 MGI:2388867 NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
JBrowse link
G Gmnn geminin, DNA replication inhibitor involved_in ISO (PMID:24064211) RGD PMID:24064211 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO
ISS
(PMID:26620551)
GO_REF:0000024
RGD
UniProt
PMID:26620551 GO_REF:0000024 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein involved_in ISO
IEA
(PMID:24064211)
GO_REF:0000107
RGD
Ensembl
PMID:24064211 GO_REF:0000107 NCBI chr 2:44,636,820...44,644,551
Ensembl chr 2:44,636,856...44,642,601
JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in ISO
IBA
(PMID:20116089)
GO_REF:0000033
RGD
GO_Central
PMID:20116089 GO_REF:0000033 NCBI chr 1:133,597,618...133,639,513
Ensembl chr 1:133,597,716...133,639,523
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 involved_in ISO
IEA
ISS
(PMID:15670210)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15670210 GO_REF:0000024 GO_REF:0000107 NCBI chr17:31,621,410...31,641,659
Ensembl chr17:31,621,411...31,641,659
JBrowse link
positive regulation of DNA-templated DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1920234 (PMID:20215406)
Ensembl
RGD
PMID:20215406 GO_REF:0000107 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:104772 (PMID:15585571), (PMID:20215406) RGD PMID:15585571 PMID:20215406 NCBI chr 3:15,658,479...15,673,762
Ensembl chr 3:15,658,539...15,673,762
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      macromolecule metabolic process 9396
        nucleic acid metabolic process 5006
          DNA metabolic process 958
            DNA replication initiation 33
              regulation of DNA-templated DNA replication initiation 8
                negative regulation of DNA-templated DNA replication initiation + 0
                positive regulation of DNA-templated DNA replication initiation + 2
                regulation of DNA replication initiation involved in plasmid copy number maintenance + 0
                regulation of initiation of premeiotic DNA replication + 0
                regulation of mitotic DNA replication initiation + 0
Path 2
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      primary metabolic process 10139
        nucleobase-containing compound metabolic process 5587
          nucleic acid metabolic process 5006
            DNA metabolic process 958
              DNA replication 272
                DNA-templated DNA replication 158
                  DNA replication initiation 33
                    regulation of DNA-templated DNA replication initiation 8
                      negative regulation of DNA-templated DNA replication initiation + 0
                      positive regulation of DNA-templated DNA replication initiation + 2
                      regulation of DNA replication initiation involved in plasmid copy number maintenance + 0
                      regulation of initiation of premeiotic DNA replication + 0
                      regulation of mitotic DNA replication initiation + 0
paths to the root