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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of DNA-dependent DNA replication initiation
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Accession:GO:0030174 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
Synonyms:exact_synonym: DNA replication licencing;   DNA replication licensing
 broad_synonym: regulation of DNA replication initiation


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regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdt1 chromatin licensing and DNA replication factor 1 involved_in ISO
IBA
(PMID:11125146)
(MGI:2388867|PMID:12192004)
PMID:21873635
RGD PMID:11125146 PMID:12192004, PMID:21873635 MGI:2388867, RGD:13792537 NCBI chr19:55,381,565...55,386,511
Ensembl chr19:55,381,565...55,386,511
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISO
ISS
IEA
(PMID:26620551)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:26620551 GO_REF:0000024 GO_REF:0000107 NCBI chr10:83,095,067...83,128,342
Ensembl chr10:83,095,068...83,128,297
JBrowse link
G Ticrr TOPBP1-interacting checkpoint and replication regulator involved_in ISO
IBA
(PMID:20116089)
PMID:21873635
RGD PMID:20116089, PMID:21873635 RGD:13792537 NCBI chr 1:141,391,738...141,433,615
Ensembl chr 1:141,391,262...141,433,109
JBrowse link
G Wdr18 WD repeat domain 18 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:12,561,318...12,569,120
Ensembl chr 7:12,561,324...12,569,143
JBrowse link
G Wrnip1 WRN helicase interacting protein 1 involved_in ISO
IEA
ISS
(PMID:15670210)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:15670210 GO_REF:0000024 GO_REF:0000107 NCBI chr17:32,933,395...32,953,641
Ensembl chr17:32,933,396...32,953,641
JBrowse link
positive regulation of DNA-dependent DNA replication initiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk2 cyclin dependent kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1920234 (MGI:4439421|PMID:20215406)
Ensembl
RGD
PMID:20215406 GO_REF:0000107 MGI:4439421 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 acts_upstream_of_or_within ISO MGI:104772 (MGI:3513706|PMID:15585571), (MGI:4439421|PMID:20215406) RGD PMID:15585571 PMID:20215406 MGI:3513706 MGI:4439421 NCBI chr 3:11,392,046...11,409,218
Ensembl chr 3:11,392,791...11,410,180
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      regulation of metabolic process 6762
        regulation of macromolecule metabolic process 6271
          regulation of DNA metabolic process 391
            regulation of DNA-dependent DNA replication initiation 7
              negative regulation of DNA-dependent DNA replication initiation + 0
              positive regulation of DNA-dependent DNA replication initiation + 2
              regulation of DNA replication initiation involved in plasmid copy number maintenance + 0
              regulation of initiation of premeiotic DNA replication + 0
              regulation of mitotic DNA replication initiation + 0
Path 2
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      organic substance metabolic process 11392
        macromolecule metabolic process 9848
          macromolecule biosynthetic process 5097
            cellular macromolecule biosynthetic process 5055
              DNA replication 256
                DNA-dependent DNA replication 154
                  DNA replication initiation 30
                    regulation of DNA-dependent DNA replication initiation 7
                      negative regulation of DNA-dependent DNA replication initiation + 0
                      positive regulation of DNA-dependent DNA replication initiation + 2
                      regulation of DNA replication initiation involved in plasmid copy number maintenance + 0
                      regulation of initiation of premeiotic DNA replication + 0
                      regulation of mitotic DNA replication initiation + 0
paths to the root