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ONTOLOGY REPORT - ANNOTATIONS


Term:platelet activation
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Accession:GO:0030168 term browser browse the term
Definition:A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
Synonyms:exact_synonym: blood coagulation, platelet activation



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platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 NOT|involved_in ISO (PMID:24069336) RGD PMID:24069336 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Adra2a adrenoceptor alpha 2A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adra2b adrenoceptor alpha 2B involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 3:114,585,174...114,589,220
Ensembl chr 3:114,585,169...114,589,355
JBrowse link
G Adra2c adrenoceptor alpha 2C involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:75,471,143...75,472,846
Ensembl chr14:75,471,143...75,472,846
JBrowse link
G Axl Axl receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2387750 (MGI:3528131|PMID:15650770)
RGD PMID:15650770 PMID:21873635 MGI:3528131, RGD:13792537 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 involved_in ISO (PMID:16385460) RGD PMID:16385460 NCBI chr 1:79,155,914...79,158,326
Ensembl chr 1:79,155,693...79,158,505
JBrowse link
G C1galt1c1 C1GALT1-specific chaperone 1 acts_upstream_of_or_within ISO MGI:4459539 (MGI:5448092|PMID:22988088) RGD PMID:22988088 MGI:5448092 NCBI chr  X:117,378,123...117,382,620
Ensembl chr  X:117,375,525...117,382,787
JBrowse link
G Cd40lg CD40 ligand involved_in IEA
ISO
ISS
GO_REF:0000104
(PMID:9468137)
GO_REF:0000024
UniProt
RGD
PMID:9468137 GO_REF:0000024 GO_REF:0000104 NCBI chr  X:135,127,119...135,138,302
Ensembl chr  X:135,126,969...135,138,306
JBrowse link
G Ctsg cathepsin G involved_in ISO
ISS
(PMID:10702240)
GO_REF:0000024
RGD
UniProt
PMID:10702240 GO_REF:0000024 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IMP RGD PMID:12969973 RGD:4891996 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 acts_upstream_of_or_within ISO (MGI:2178511|PMID:11929769) RGD PMID:11929769 MGI:2178511 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2178511|PMID:11929769)
Ensembl
RGD
PMID:11929769 GO_REF:0000107 MGI:2178511 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866
JBrowse link
G F2 coagulation factor II involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
(MGI:3709713|PMID:17380206)
PMID:21873635
(PMID:9038223)
Ensembl
RGD
PMID:9038223 PMID:17380206 PMID:21873635 GO_REF:0000107 MGI:3709713, RGD:13792537 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:9038223)
UniProt
Ensembl
RGD
PMID:9038223 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 involved_in ISO (PMID:10702240) RGD PMID:10702240 NCBI chr16:17,117,441...17,119,434
Ensembl chr16:17,117,441...17,119,472
JBrowse link
G Fga fibrinogen alpha chain involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fzd6 frizzled class receptor 6 acts_upstream_of_or_within ISO MGI:3050103 (MGI:4398768|PMID:19901330) RGD PMID:19901330 MGI:4398768 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gna13 G protein subunit alpha 13 acts_upstream_of_or_within ISO MGI:2151775 (MGI:3583058|PMID:14528298) RGD PMID:14528298 MGI:3583058 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
ISO
GO_REF:0000024
(PMID:19903770)
UniProt
RGD
PMID:19903770 GO_REF:0000024 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G Itgb3 integrin subunit beta 3 involved_in ISO (PMID:15466936) RGD PMID:15466936 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase acts_upstream_of_or_within ISO MGI:2387765 (MGI:3528131|PMID:15650770) RGD PMID:15650770 MGI:3528131 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
JBrowse link
G P2rx1 purinergic receptor P2X 1 acts_upstream_of_or_within ISO MGI:2181608 (MGI:2671726|PMID:12913094) RGD PMID:12913094 MGI:2671726 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
JBrowse link
G P2ry12 purinergic receptor P2Y12 acts_upstream_of_or_within ISO MGI:2445936 (MGI:2136079|PMID:11413167) RGD PMID:11413167 MGI:2136079 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pf4 platelet factor 4 involved_in ISO
ISS
(PMID:11685038)
GO_REF:0000024
RGD
UniProt
PMID:11685038 GO_REF:0000024 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3577829|PMID:15834429)
Ensembl
RGD
PMID:15834429 GO_REF:0000107 MGI:3577829 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Ppbp pro-platelet basic protein TAS RGD PMID:11785982 RGD:70252 NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO
GO_REF:0000024
(MGI:6450355|PMID:24429998)
UniProt
RGD
PMID:24429998 GO_REF:0000024 MGI:6450355 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310
JBrowse link
G Rap2b RAP2B, member of RAS oncogene family involved_in ISO (PMID:18582561) RGD PMID:18582561 NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069
JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO MGI:3522206|MGI:3764698 (MGI:4834086|PMID:20525922) RGD PMID:20525922 MGI:4834086 NCBI chr 9:14,426,453...14,435,734
Ensembl chr 9:14,426,472...14,435,733
JBrowse link
G Treml1 triggering receptor expressed on myeloid cells-like 1 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:15128762)
(PMID:15100151)
PMID:21873635
RGD PMID:15100151 PMID:15128762 PMID:21873635 RGD:13792537 NCBI chr 9:12,635,584...12,642,929
Ensembl chr 9:12,635,590...12,642,347
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2387762 (MGI:3528131|PMID:15650770)
UniProt
RGD
PMID:15650770 GO_REF:0000024 MGI:3528131 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO MGI:2670555 (MGI:5811934|PMID:27609517) RGD PMID:27609517 MGI:5811934 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
G Vwf von Willebrand factor involved_in
NOT|acts_upstream_of_or_within
IMP
IEA
ISO
GO_REF:0000104
MGI:2153009 (MGI:3709713|PMID:17380206)
MGI:2153009 (MGI:1861538|PMID:10930441), (MGI:4888158|PMID:21037087)
(PMID:8565074)
UniProt
RGD
PMID:8565074 PMID:10930441 PMID:17380206 PMID:21037087 PMID:10709908 More... GO_REF:0000104 MGI:1861538 MGI:3709713 MGI:4888158, RGD:1599012, RGD:1599016 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (MGI:4398768|PMID:19901330) RGD PMID:19901330 MGI:4398768 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
negative regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IEA
ISO
GO_REF:0000107
(PMID:8995232)
Ensembl
RGD
PMID:8995232 GO_REF:0000107 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO (PMID:16195328) RGD PMID:16195328 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G Gp5 glycoprotein V (platelet) acts_upstream_of_or_within ISO MGI:2652408 (MGI:1347746|PMID:10557321), (MGI:2137180|PMID:11435305) RGD PMID:10557321 PMID:11435305 MGI:1347746 MGI:2137180 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Pdgfa platelet derived growth factor subunit A involved_in ISO
ISS
(PMID:2538439)
GO_REF:0000024
RGD
UniProt
PMID:2538439 GO_REF:0000024 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
ISS
IEA
(PMID:2538439)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:2538439 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:8188664)
UniProt
Ensembl
RGD
PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Serpine2 serpin family E member 2 acts_upstream_of_or_within ISO MGI:2387774 (MGI:4418017|PMID:19855083) RGD PMID:19855083 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
negative regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abat 4-aminobutyrate aminotransferase IMP RGD PMID:12742000 RGD:10047059 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif, 18 acts_upstream_of_or_within ISO (MGI:3848389|PMID:19218546)
(PMID:19218546)
RGD PMID:19218546 MGI:3848389 NCBI chr19:41,686,951...41,840,035
Ensembl chr19:41,688,617...41,839,781
JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:6140045 RGD:8548522 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISS
ISO
GO_REF:0000024
(MGI:1202206|PMID:9501222)
UniProt
RGD
PMID:9501222 GO_REF:0000024 MGI:1202206 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542
JBrowse link
G C1qtnf1 C1q and TNF related 1 involved_in ISO
IEA
(PMID:16195328)
GO_REF:0000107
RGD
Ensembl
PMID:16195328 GO_REF:0000107 NCBI chr10:103,660,319...103,681,662
Ensembl chr10:103,660,327...103,681,660
JBrowse link
G Cd9 CD9 molecule involved_in ISS
ISO
GO_REF:0000024
(PMID:18541721)
UniProt
RGD
PMID:18541721 GO_REF:0000024 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3835235|PMID:19008452)
UniProt
RGD
PMID:19008452 GO_REF:0000024 MGI:3835235 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Fgg fibrinogen gamma chain IDA RGD PMID:22985603 RGD:11352706 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Prkcd protein kinase C, delta involved_in ISS
ISO
GO_REF:0000024
(MGI:3813784|PMID:16940418)
UniProt
RGD
PMID:16940418 GO_REF:0000024 MGI:3813784 NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 involved_in ISO (PMID:16990611) RGD PMID:16990611 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
G Ptger3 prostaglandin E receptor 3 IMP RGD PMID:20303752 RGD:10043327 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
JBrowse link
G Serpine2 serpin family E member 2 involved_in IEA
ISO
GO_REF:0000107
(MGI:4418017|PMID:19855083)
Ensembl
RGD
PMID:19855083 GO_REF:0000107 MGI:4418017 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Sh2b3 SH2B adaptor protein 3 involved_in IEA
ISO
GO_REF:0000107
UniProtKB:P35951 (MGI:5905608|PMID:27430239)
Ensembl
RGD
PMID:27430239 GO_REF:0000107 MGI:5905608 NCBI chr12:34,749,849...34,753,616
Ensembl chr12:34,731,911...34,753,616
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B acts_upstream_of_or_within ISO (MGI:4838721|PMID:20585042) RGD PMID:20585042 MGI:4838721 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actb actin, beta involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
JBrowse link
G Actg1 actin, gamma 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Actn1 actinin, alpha 1 NOT|involved_in ISO (PMID:23434115) RGD PMID:23434115 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Bloc1s4 biogenesis of lysosomal organelles complex 1 subunit 4 acts_upstream_of_or_within ISO MGI:2449643 (MGI:1354542|PMID:11110696) RGD PMID:11110696 MGI:1354542 NCBI chr14:74,043,025...74,044,325
Ensembl chr14:74,043,015...74,044,531
JBrowse link
G Cfh complement factor H acts_upstream_of_or_within ISO (MGI:5883383|PMID:28057640) RGD PMID:28057640 MGI:5883383 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838
JBrowse link
G Clic1 chloride intracellular channel 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712
JBrowse link
G Comp cartilage oligomeric matrix protein involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2180787 (MGI:5694900|PMID:26045608)
Ensembl
RGD
PMID:26045608 GO_REF:0000107 MGI:5694900 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Fermt3 FERM domain containing kindlin 3 involved_in IBA
ISO
PMID:21873635
(MGI:3783912|PMID:18278053)
RGD PMID:18278053 PMID:21873635 MGI:3783912, RGD:13792537 NCBI chr 1:204,189,483...204,207,683
Ensembl chr 1:204,189,484...204,207,587
JBrowse link
G Fga fibrinogen alpha chain involved_in ISO
IBA
(PMID:6281794)
PMID:21873635
RGD PMID:6281794 PMID:21873635 RGD:13792537 NCBI chr 2:168,365,364...168,381,533
Ensembl chr 2:168,374,120...168,381,528
JBrowse link
G Fgb fibrinogen beta chain involved_in ISO
IBA
(PMID:6281794)
PMID:21873635
RGD PMID:6281794 PMID:21873635 RGD:13792537 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
JBrowse link
G Fgg fibrinogen gamma chain involved_in ISO
IBA
(PMID:6281794)
PMID:21873635
RGD PMID:6281794 PMID:21873635 RGD:13792537 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
JBrowse link
G Fibp FGF1 intracellular binding protein involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 1:202,768,065...202,772,405
Ensembl chr 1:202,768,078...202,772,399
JBrowse link
G Flna filamin A involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr  X:152,007,758...152,034,266
Ensembl chr  X:152,007,758...152,031,052
JBrowse link
G Fn1 fibronectin 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:15701726)
(MGI:3580921|PMID:15701726)
RGD PMID:15701726 MGI:3580921 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530
JBrowse link
G Gnas GNAS complex locus involved_in ISO (PMID:12719376) RGD PMID:12719376 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,136,350
Ensembl chr 3:163,071,417...163,136,350
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:10727447 PMID:21873635 RGD:10450868, RGD:13792537 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Hbb hemoglobin subunit beta involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Ilk integrin-linked kinase involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Itga2b integrin subunit alpha 2b IMP RGD PMID:17924279 RGD:2316357 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
JBrowse link
G Itgb3 integrin subunit beta 3 involved_in IMP
ISO
IEA
(PMID:15466936)
GO_REF:0000002
RGD
InterPro
PMID:15466936 PMID:17924279 GO_REF:0000002, RGD:2316357 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679
JBrowse link
G Metap1 methionyl aminopeptidase 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 2:226,991,305...227,024,360
Ensembl chr 2:226,991,301...227,024,434
JBrowse link
G Mpl MPL proto-oncogene, thrombopoietin receptor IEP RGD PMID:15670044 RGD:10448997 NCBI chr 5:131,973,897...131,987,472
Ensembl chr 5:131,973,895...131,986,797
JBrowse link
G Myh9 myosin, heavy chain 9 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G Myl12a myosin light chain 12A involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 9:110,891,970...110,899,655
Ensembl chr 9:110,873,959...110,916,580
JBrowse link
G Myl9 myosin light chain 9 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G P2ry12 purinergic receptor P2Y12 involved_in IMP
ISO
(PMID:12578987) RGD PMID:12578987 PMID:19028049 RGD:6480528 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361
JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in ISO
IEA
ISS
(PMID:8188664)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8188664 GO_REF:0000024 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pear1 platelet endothelial aggregation receptor 1 involved_in ISO (MGI:5817200|PMID:27614188) RGD PMID:27614188 MGI:5817200 NCBI chr 2:173,206,298...173,234,106
Ensembl chr 2:173,207,664...173,227,440
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma acts_upstream_of_or_within ISO MGI:2385922|MGI:5496877 (MGI:5488558|PMID:23372168) RGD PMID:23372168 MGI:5488558 NCBI chr 7:8,397,406...8,426,030
Ensembl chr 7:8,397,406...8,425,988
JBrowse link
G Plek pleckstrin involved_in ISO
IEA
(MGI:3844782|PMID:19190246)
GO_REF:0000107
RGD
Ensembl
PMID:19190246 GO_REF:0000107 MGI:3844782 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Ppia peptidylprolyl isomerase A involved_in ISS
ISO
GO_REF:0000024
(MGI:6450355|PMID:24429998)
UniProt
RGD
PMID:24429998 GO_REF:0000024 MGI:6450355 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppial4d peptidylprolyl isomerase A (cyclophilin A)-like 4D involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr14:21,006,522...21,007,284
Ensembl chr14:21,006,538...21,007,310
JBrowse link
G Ptpn6 protein tyrosine phosphatase, non-receptor type 6 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3719625 (MGI:5494903|PMID:23509158)
Ensembl
RGD
PMID:23509158 GO_REF:0000107 MGI:5494903 NCBI chr 4:157,526,034...157,550,783
Ensembl chr 4:157,526,035...157,550,984
JBrowse link
G Rap2b RAP2B, member of RAS oncogene family involved_in ISO (PMID:18582561) RGD PMID:18582561 NCBI chr 2:145,599,714...145,600,265
Ensembl chr 2:145,599,116...145,603,069
JBrowse link
G Slc7a11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO MGI:1857061 (MGI:79102|PMID:8699821) RGD PMID:8699821 MGI:79102 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (PMID:12773094) RGD PMID:12773094 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in ISO (PMID:12773094) RGD PMID:12773094 NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671
JBrowse link
G Tln1 talin 1 involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr 5:57,787,670...57,817,900
Ensembl chr 5:57,787,943...57,817,900
JBrowse link
G Tspan32 tetraspanin 32 acts_upstream_of_or_within ISO MGI:2183564 (MGI:3804129|PMID:16720835) RGD PMID:16720835 MGI:3804129 NCBI chr 1:198,190,128...198,204,447
Ensembl chr 1:198,190,164...198,204,445
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5306558|PMID:20546121)
GO_REF:0000024
RGD
UniProt
PMID:20546121 PMID:21873635 GO_REF:0000024 MGI:5306558, RGD:13792537 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
JBrowse link
G Ubash3a ubiquitin associated and SH3 domain containing, A NOT|acts_upstream_of_or_within ISO MGI:3051962 (MGI:5811934|PMID:27609517) RGD PMID:27609517 MGI:5811934 NCBI chr20:9,291,471...9,334,685
Ensembl chr20:9,292,139...9,329,224
JBrowse link
G Ubash3b ubiquitin associated and SH3 domain containing, B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2670555 (MGI:5811934|PMID:27609517)
RGD PMID:27609517 PMID:21873635 MGI:5811934, RGD:13792537 NCBI chr 8:41,385,419...41,532,248
Ensembl chr 8:41,388,341...41,532,201
JBrowse link
G Vcl vinculin involved_in ISO (PMID:23382103) UniProt PMID:23382103 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Wnt3a Wnt family member 3A acts_upstream_of_or_within ISO (MGI:4398768|PMID:19901330) RGD PMID:19901330 MGI:4398768 NCBI chr10:44,034,174...44,078,463
Ensembl chr10:44,034,194...44,078,324
JBrowse link
positive regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp1ba glycoprotein Ib platelet subunit alpha involved_in ISO
IEA
(PMID:1939645)
GO_REF:0000107
RGD
Ensembl
PMID:1939645 GO_REF:0000107 NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774
JBrowse link
G Gp1bb glycoprotein Ib platelet subunit beta involved_in ISO
IEA
(PMID:1939645)
GO_REF:0000107
RGD
Ensembl
PMID:1939645 GO_REF:0000107 NCBI chr11:82,378,216...82,379,393
Ensembl chr11:82,378,199...82,379,392
JBrowse link
G Gp5 glycoprotein V (platelet) involved_in ISO (PMID:1939645) RGD PMID:1939645 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Gp9 glycoprotein IX (platelet) involved_in ISO
IEA
(PMID:1939645)
GO_REF:0000107
RGD
Ensembl
PMID:1939645 GO_REF:0000107 NCBI chr 4:120,235,539...120,236,874
Ensembl chr 4:120,235,421...120,237,110
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of_or_within ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Pdpn podoplanin IMP RGD PMID:16979138 RGD:2292241 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO
IEA
(PMID:18451993)
GO_REF:0000107
RGD
Ensembl
PMID:18451993 GO_REF:0000107 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Plek pleckstrin involved_in ISO
IEA
(MGI:3844782|PMID:19190246)
GO_REF:0000107
RGD
Ensembl
PMID:19190246 GO_REF:0000107 MGI:3844782 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J involved_in ISO (MGI:3847185|PMID:19246339) RGD PMID:19246339 MGI:3847185 NCBI chr 3:76,405,917...76,561,842
Ensembl chr 3:76,405,927...76,562,260
JBrowse link
G Selp selectin P involved_in IEA
ISO
GO_REF:0000107
(MGI:3838274|PMID:16514062)
Ensembl
RGD
PMID:16514062 GO_REF:0000107 MGI:3838274 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
JBrowse link
G Tlr4 toll-like receptor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:3838274|PMID:16514062)
Ensembl
RGD
PMID:16514062 GO_REF:0000107 MGI:3838274 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
positive regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsg cathepsin G involved_in ISO
ISS
(PMID:3390156)
GO_REF:0000024
RGD
UniProt
PMID:3390156 GO_REF:0000024 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
JBrowse link
G Dmtn dematin actin binding protein involved_in ISO (MGI:5465511|PMID:23060452) RGD PMID:23060452 MGI:5465511 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601
JBrowse link
G Emilin2 elastin microfibril interfacer 2 involved_in ISO
IEA
(PMID:25658937)
GO_REF:0000107
RGD
Ensembl
PMID:25658937 GO_REF:0000107 NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352
JBrowse link
G F11r F11 receptor involved_in ISO (PMID:15344881) RGD PMID:15344881 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402
JBrowse link
G Il6 interleukin 6 acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Jak2 Janus kinase 2 acts_upstream_of ISO (PMID:31145836) RGD PMID:31145836 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Mmrn1 multimerin 1 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:19175495)
GO_REF:0000107
(PMID:20138333)
(MGI:6850200|PMID:20138333)
RGD
Ensembl
PMID:19175495 PMID:20138333 GO_REF:0000107 MGI:6850200 NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474
JBrowse link
G Pdpn podoplanin involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3722196|PMID:17616532), (MGI:4453945|PMID:20110424)
PMID:21873635
(PMID:17222411), (PMID:17616532), (PMID:18541721), (PMID:20110424)
UniProt
RGD
PMID:17222411 PMID:17616532 PMID:18541721 PMID:20110424 PMID:21873635 GO_REF:0000024 MGI:3722196 MGI:4453945, RGD:13792537 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
regulation of platelet activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fcer1g Fc epsilon receptor Ig involved_in IBA
ISO
PMID:21873635
(MGI:87668|PMID:9171347)
RGD PMID:9171347 PMID:21873635 MGI:87668, RGD:13792537 NCBI chr13:83,649,447...83,654,215
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fundc2 FUN14 domain containing 2 involved_in ISO (MGI:6506888|PMID:30576423) RGD PMID:30576423 MGI:6506888 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
ISO
IBA
GO_REF:0000024
(MGI:3789419|PMID:15869579), (MGI:4941083|PMID:21264222)
PMID:21873635
UniProt
RGD
PMID:15869579 PMID:21264222 PMID:21873635 GO_REF:0000024 MGI:3789419 MGI:4941083, RGD:13792537 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389
JBrowse link
G LOC681544 similar to histidine-rich glycoprotein involved_in ISS
IBA
GO_REF:0000024
PMID:21873635
UniProt PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353
JBrowse link
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
GO_REF:0000024
(MGI:87668|PMID:9171347)
UniProt
RGD
PMID:9171347 GO_REF:0000024 MGI:87668 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Tec tec protein tyrosine kinase involved_in IBA
ISO
PMID:21873635
(PMID:9299487), (PMID:9652744)
RGD PMID:9299487 PMID:9652744 PMID:21873635 RGD:13792537 NCBI chr14:35,352,551...35,461,585
Ensembl chr14:35,352,829...35,461,557
JBrowse link
G Txk TXK tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:35,463,369...35,519,448
Ensembl chr14:35,463,944...35,519,448
JBrowse link
regulation of platelet aggregation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk BLK proto-oncogene, Src family tyrosine kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031
JBrowse link
G Cela2a chymotrypsin like elastase 2A involved_in ISO
ISS
(PMID:31358993)
GO_REF:0000024
RGD
UniProt
PMID:31358993 GO_REF:0000024 NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
ISS
PMID:21873635
(MGI:5298337|PMID:20189992)
GO_REF:0000024
RGD
UniProt
PMID:20189992 PMID:21873635 GO_REF:0000024 MGI:5298337, RGD:13792537 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Prkca protein kinase C, alpha involved_in ISO
ISS
(PMID:12724315)
(MGI:3836381|PMID:19147982)
GO_REF:0000024
RGD
UniProt
PMID:12724315 PMID:19147982 GO_REF:0000024 MGI:3836381 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
JBrowse link
G Prkcq protein kinase C, theta involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:3851048|PMID:19433059)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:19433059 GO_REF:0000024 GO_REF:0000107 MGI:3851048 NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
JBrowse link
G Syk spleen associated tyrosine kinase involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:87668|PMID:9171347)
PMID:21873635
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9171347 PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:87668, RGD:13792537 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
JBrowse link
G Vps33b VPS33B, late endosome and lysosome associated involved_in ISO (MGI:5645581|PMID:25947942) RGD PMID:25947942 MGI:5645581 NCBI chr 1:134,223,967...134,247,232
Ensembl chr 1:134,223,949...134,246,970
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19512
    cellular process 18319
      cell activation 1222
        platelet activation 116
          negative regulation of platelet activation + 19
          platelet aggregation + 76
          positive regulation of platelet activation 11
          regulation of platelet activation + 49
Path 2
Term Annotations click to browse term
  biological_process 19512
    biological regulation 13616
      regulation of biological quality 4216
        regulation of body fluid levels 430
          hemostasis 197
            blood coagulation 194
              platelet activation 116
                negative regulation of platelet activation + 19
                platelet aggregation + 76
                positive regulation of platelet activation 11
                regulation of platelet activation + 49
paths to the root