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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteolysis
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Accession:GO:0030162 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: regulation of peptidolysis


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regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2CD3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:8,393,610...8,512,843
Ensembl chr 9:8,393,612...8,512,848 		JBrowse link
G GSAP gamma-secretase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:102,694,846...102,785,208
Ensembl chr 9:102,694,861...102,787,536 		JBrowse link
G NEDD8 NEDD8 ubiquitin like modifier involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:75,069,947...75,085,905
Ensembl chr 7:75,070,161...75,085,899 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:121,758,734...121,813,679
Ensembl chr13:121,758,738...121,813,638 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO positive regulation of cysteine-type endopeptidase activity RGD PMID:18278556 RGD:401965430 NCBI chr17:52,017,100...52,086,747
Ensembl chr17:52,017,130...52,086,736 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SPOP speckle type BTB/POZ protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:25,792,621...25,860,630
Ensembl chr12:25,792,630...25,860,595 		JBrowse link
G SPOPL speckle type BTB/POZ protein like involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:13,134,221...13,207,737
Ensembl chr15:13,134,225...13,207,731 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in ISO (PMID:27179792) ARUK-UCL PMID:27179792 NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652 		JBrowse link
G TMED10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within ISO (PMID:16641999) MGI PMID:16641999 NCBI chr 7:98,327,402...98,362,652
Ensembl chr 7:98,327,408...98,362,606 		JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO RGD PMID:19240864 RGD:7411612 NCBI chr 5:62,406,928...62,483,690
Ensembl chr 5:62,440,810...62,483,678 		JBrowse link
G CRB2 crumbs cell polarity complex component 2 involved_in ISO (PMID:20299451) UniProt PMID:20299451 NCBI chr 1:264,277,549...264,301,731
Ensembl chr 1:264,276,987...264,301,713 		JBrowse link
G FETUB fetuin B involved_in ISO (PMID:23562279) UniProt PMID:23562279 NCBI chr13:124,480,456...124,494,197
Ensembl chr13:124,460,272...124,494,196 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:22832495) UniProt PMID:22832495 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
G RENBP renin binding protein ISO RGD PMID:11926999 RGD:727355 NCBI chr  X:124,662,957...124,670,522
Ensembl chr  X:124,662,719...124,672,235 		JBrowse link
G SERPINB1 serpin family B member 1 involved_in ISO (PMID:30692621) UniProt PMID:30692621 NCBI chr 7:1,684,212...1,693,313
Ensembl chr 7:1,684,215...1,693,299 		JBrowse link
G SERPINB13 serpin family B member 13 involved_in ISO (PMID:12504904) UniProt PMID:12504904 NCBI chr 1:158,099,811...158,113,526
Ensembl chr 1:158,099,975...158,113,501 		JBrowse link
G SERPINB8 serpin family B member 8 involved_in ISO (PMID:8530382) UniProt PMID:8530382 NCBI chr 1:157,820,641...157,836,922
Ensembl chr 1:157,820,657...157,836,904 		JBrowse link
G SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 involved_in ISO (PMID:21795594) UniProt PMID:21795594 NCBI chr 7:1,723,302...1,732,562
Ensembl chr 7:1,721,383...1,735,074 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:10717410 RGD:8547889 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 involved_in ISO (PMID:11751414) UniProt PMID:11751414 NCBI chr14:21,754,419...22,121,051
Ensembl chr14:21,754,539...22,121,044 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,296 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:12,065,550...12,076,339
Ensembl chr 9:12,065,546...12,078,401 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,879,081...75,896,279
Ensembl chr 2:75,879,058...75,896,277 		JBrowse link
G SVIP small VCP interacting protein involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:36,703,757...36,714,018
Ensembl chr 2:36,703,790...36,714,934 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:9,072,549...9,075,595
Ensembl chr 2:9,072,968...9,075,594 		JBrowse link
G UBXN2A UBX domain protein 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:114,667,278...114,714,185
Ensembl chr 3:114,673,035...114,714,178 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:106,087,921...106,139,717
Ensembl chr 6:106,087,924...106,139,379 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:180,571,019...180,708,966
Ensembl chr13:180,571,342...180,712,435 		JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G LOC110261265 metalloproteinase inhibitor 1-like involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:10,760,556...10,762,615 JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:107,348,662...107,511,308
Ensembl chr 4:107,348,669...107,492,516 		JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:250,418,131...250,583,148
Ensembl chr 1:250,418,133...250,540,480 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,296 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr13:68,179,803...68,191,199
Ensembl chr13:68,179,806...68,190,942 		JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in ISO (PMID:9573338) UniProt PMID:9573338 NCBI chr  X:42,103,251...42,106,289
Ensembl chr  X:42,102,172...42,106,296 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in ISO (PMID:9573338) UniProt PMID:9573338 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834 		JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAST calpastatin acts_upstream_of_or_within ISO (PMID:21849499) MGI PMID:21849499 NCBI chr 2:103,255,738...103,378,623
Ensembl chr 2:103,255,750...103,378,623 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in ISO (PMID:16512877) UniProt PMID:16512877 NCBI chr 4:98,615,776...98,633,081
Ensembl chr 4:98,615,778...98,621,836 		JBrowse link
G LOC110261636 serpin B3-like involved_in ISO (PMID:12949073) UniProt PMID:12949073 NCBI chr 1:158,073,431...158,079,267 JBrowse link
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within ISO (PMID:15509762), (PMID:18398001) MGI PMID:15509762 PMID:18398001 NCBI chr15:125,748,383...125,777,788
Ensembl chr15:125,748,394...125,816,215 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (PMID:3428272) MGI PMID:3428272 NCBI chr 2:149,072,652...149,079,529
Ensembl chr 2:149,071,703...149,079,499 		JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPB2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chr11:21,234,447...21,298,250
Ensembl chr11:21,234,447...21,298,241 		JBrowse link
G CTSZ cathepsin Z involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:59,141,497...59,149,377
Ensembl chr17:59,138,621...59,149,377 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr15:125,748,383...125,777,788
Ensembl chr15:125,748,394...125,816,215 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,934,551...47,942,283
Ensembl chr12:47,933,864...47,942,285 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,784...131,746,115 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:254,015,426...254,027,584
Ensembl chr 1:254,011,833...254,027,537 		JBrowse link
G F8A1 coagulation factor VIII-associated 1 involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:125,280,978...125,282,771 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in ISO (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr 6:12,122,219...12,132,986
Ensembl chr 6:12,107,422...12,132,991 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,250,481 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr13:121,081,717...121,117,660
Ensembl chr13:121,081,424...121,117,665 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:66,649,363...66,699,647
Ensembl chr15:66,649,049...66,699,950 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:54,056,504...54,617,045
Ensembl chr  X:54,055,092...54,616,959 		JBrowse link
G PRKCG protein kinase C gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,213,479...56,235,683
Ensembl chr 6:56,213,480...56,234,210 		JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:19,098,097...19,154,288
Ensembl chr 6:19,102,013...19,154,177 		JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:34,118,324...34,164,723
Ensembl chr17:34,098,991...34,169,287 		JBrowse link
G SCO1 synthesis of cytochrome C oxidase 1 acts_upstream_of_or_within ISO (PMID:25683716) MGI PMID:25683716 NCBI chr12:55,406,730...55,424,120
Ensembl chr12:55,405,483...55,424,118 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in ISO (PMID:25088257) ParkinsonsUK-UCL PMID:25088257 NCBI chr13:31,726,668...31,738,135
Ensembl chr13:31,726,672...31,737,981 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107
G BAG6 BAG cochaperone 6 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,897...23,768,666 		JBrowse link
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:136,957,626...136,967,944
Ensembl chr 2:136,957,508...136,968,382 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:6,860,052...6,874,334
Ensembl chr14:6,859,664...6,874,327 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,320 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr17:34,692,960...34,748,067 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:19,975,030...20,016,768
Ensembl chr 6:19,976,930...20,016,923 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,781,194...23,787,914
Ensembl chr 7:23,780,210...23,792,502
Ensembl chr 7:23,780,210...23,792,502 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:21,955,026...22,053,683
Ensembl chr 4:21,954,874...22,058,699 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:41,443,963...42,884,799
Ensembl chr13:41,443,965...42,392,817 		JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,780,447...64,794,922
Ensembl chr 2:64,780,442...64,794,919 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:39,237,299...39,250,479
Ensembl chr 7:39,244,458...39,250,481 		JBrowse link
G KLHL40 kelch like family member 40 involved_in
acts_upstream_of_or_within 		IBA
ISO 		(PMID:24960163) GO_Central
MGI		 PMID:24960163 GO_REF:0000033 NCBI chr13:26,202,607...26,211,528
Ensembl chr13:26,202,677...26,211,522 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (PMID:26609151) ARUK-UCL PMID:26609151 NCBI chr 1:127,916,639...127,936,952
Ensembl chr 1:127,916,644...127,936,955 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (PMID:23695157) MGI PMID:23695157 NCBI chr  X:122,286,904...122,379,302
Ensembl chr  X:122,286,916...122,379,299 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:36,122,189...36,177,965
Ensembl chr 6:36,122,035...36,174,504 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,443,453...53,451,707
Ensembl chr 6:53,443,385...53,452,017 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,521,091...57,558,467
Ensembl chr  X:57,521,098...57,558,515 		JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 6:68,629,327...68,645,147
Ensembl chr 6:68,629,214...68,645,516 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:11,543,657...11,577,286
Ensembl chr14:11,543,603...11,566,702 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,394,874...8,468,309
Ensembl chr 4:8,394,897...8,468,297 		JBrowse link
G RGS19 regulator of G protein signaling 19 involved_in ISO (PMID:11546783) BHF-UCL PMID:11546783 NCBI chr17:62,889,207...62,896,149
Ensembl chr17:62,889,210...62,895,556 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:81,523,510...81,526,925
Ensembl chr 6:81,522,742...81,530,436 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:53,724,062...53,809,698
Ensembl chr13:53,724,065...53,809,601 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:78,419,849...78,476,315
Ensembl chr 5:78,423,383...78,476,195 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,994...2,555,484 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:30,409,979...30,576,270
Ensembl chr13:30,409,983...30,576,327 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,494,841...47,499,568
Ensembl chr16:47,490,027...47,495,880 		JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,129,249...16,256,642
Ensembl chr12:16,129,256...16,256,359 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:23,047,048...23,062,974
Ensembl chr 7:23,047,148...23,062,972 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO (PMID:31537781) MGI PMID:31537781 NCBI chr 9:45,829,014...45,838,978
Ensembl chr 9:45,829,191...45,838,979 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:9,072,549...9,075,595
Ensembl chr 2:9,072,968...9,075,594 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:725,688...761,633
Ensembl chr10:725,561...763,985 		JBrowse link
G USP26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133) UniProt PMID:28839133 NCBI chr  X:109,092,622...109,095,548 JBrowse link
G USP38 ubiquitin specific peptidase 38 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:84,567,476...84,601,044
Ensembl chr 8:84,567,618...84,601,224 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in ISO (PMID:37534934) UniProt PMID:37534934 NCBI chr 5:63,843,742...63,858,835
Ensembl chr 5:63,843,745...63,858,716 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:33,754,357...33,810,480
Ensembl chr 3:33,775,829...33,810,465 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:36,736,049...36,888,702
Ensembl chr  X:36,760,865...36,885,250 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:39,932,562...40,024,114
Ensembl chr10:39,932,599...40,022,338 		JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,535,406...55,541,929
Ensembl chr 6:55,536,904...55,541,968 		JBrowse link
G CDH1 cadherin 1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,360,510...130,363,332
Ensembl chr 1:130,360,514...130,363,308 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:120,361,232...120,400,282
Ensembl chr  X:120,361,367...120,399,831 		JBrowse link
G GAS1 growth arrest specific 1 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:28,509,168...28,511,554
Ensembl chr10:28,509,261...28,510,301 		JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:13,011,829...13,165,487
Ensembl chr 6:13,011,837...13,165,496 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:52,367,434...52,406,393
Ensembl chr 3:52,367,437...52,406,334 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr 5:33,105,717...33,137,602
Ensembl chr 5:33,105,759...33,137,739 		JBrowse link
G MIR152 microRNA mir-152 acts_upstream_of ISO (PMID:24813629) BHF-UCL PMID:24813629 NCBI chr12:24,292,249...24,292,328
Ensembl chr12:24,292,251...24,292,336 		JBrowse link
G NLRP7 NLR family pyrin domain containing 7 involved_in ISO (PMID:15817483) UniProt PMID:15817483 NCBI chr 6:59,112,811...59,150,916 JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr 6:54,172,038...54,175,461
Ensembl chr 6:54,172,050...54,175,463 		JBrowse link
G SNX12 sorting nexin 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,099,521...57,108,636
Ensembl chr  X:57,089,136...57,108,750 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:42,087,691...42,101,152
Ensembl chr12:42,083,553...42,100,494 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr14:40,290,288...40,303,887
Ensembl chr14:40,290,288...40,303,879 		JBrowse link
negative regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192
G BAG6 BAG cochaperone 6 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,897...23,768,666 		JBrowse link
G CDK5 cyclin dependent kinase 5 involved_in ISO (PMID:24548080) ParkinsonsUK-UCL PMID:24548080 NCBI chr18:6,166,914...6,171,157 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290 		JBrowse link
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,471,056...30,474,486
Ensembl chr17:30,470,855...30,474,590 		JBrowse link
G CSTB cystatin B involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:206,706,060...206,710,598
Ensembl chr13:206,706,063...206,710,646 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:42,917,911...42,941,894
Ensembl chr  X:42,917,964...42,941,887 		JBrowse link
G IDE insulin degrading enzyme ISO inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chr14:103,992,035...104,106,571
Ensembl chr14:103,992,039...104,106,576 		JBrowse link
G KNG1 kininogen 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:124,521,276...124,557,384
Ensembl chr13:124,521,340...124,557,958 		JBrowse link
G LOC396867 stefin A8 involved_in ISO (PMID:3488317), (PMID:6203523) BHF-UCL PMID:3488317 PMID:6203523 NCBI chr13:138,216,027...138,226,397
Ensembl chr13:138,181,723...138,236,860 		JBrowse link
G MIR126 microRNA mir-126 acts_upstream_of ISO (PMID:23437250) ARUK-UCL PMID:23437250
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:55,238,536...55,245,457
Ensembl chr 6:55,239,500...55,245,456 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:15161606 RGD:1625251 NCBI chr16:46,434,757...46,523,626
Ensembl chr16:46,511,521...46,523,609 		JBrowse link
G PLAT plasminogen activator, tissue type involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G RAB23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:16364285) MGI PMID:16364285 NCBI chr 7:28,632,065...28,658,958
Ensembl chr 7:28,632,082...28,658,952 		JBrowse link
G SERPINA5 serpin family A member 5 ISO RGD PMID:16088033 RGD:1580291 NCBI chr 7:115,799,414...115,810,825
Ensembl chr 7:115,802,150...115,810,824 		JBrowse link
G SERPINB10 serpin family B member 10 ISO RGD PMID:11986314 RGD:634009 NCBI chr 1:157,841,487...157,866,913
Ensembl chr 1:157,841,510...157,866,913 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,547 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:125,748,383...125,777,788
Ensembl chr15:125,748,394...125,816,215 		JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:149,309,482...149,382,286
Ensembl chr 2:149,309,540...149,382,282 		JBrowse link
G SPINK9 serine peptidase inhibitor Kazal type 9 acts_upstream_of_or_within ISO (PMID:16930550) MGI PMID:16930550 NCBI chr 2:149,630,151...149,634,943
Ensembl chr 2:149,630,272...149,634,932 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:17532789 RGD:2290425 NCBI chr12:3,254,794...3,300,835
Ensembl chr12:3,254,493...3,300,834 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17532789 RGD:2290425 NCBI chr 5:12,185,816...12,242,599
Ensembl chr 5:12,185,818...12,242,581 		JBrowse link
G TM4SF20 transmembrane 4 L six family member 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:128,802,438...128,814,201
Ensembl chr15:128,801,849...128,814,177 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,644...52,953,818 		JBrowse link
G UBXN2A UBX domain protein 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:114,667,278...114,714,185
Ensembl chr 3:114,673,035...114,714,178 		JBrowse link
G VTN vitronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:44,650,532...44,653,916
Ensembl chr12:44,650,534...44,655,355 		JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:25217637) ParkinsonsUK-UCL
Ensembl		 PMID:25217637 GO_REF:0000107 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:94,666,457...94,673,442
Ensembl chr 4:94,666,460...94,674,071 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:123,350,867...123,501,872
Ensembl chr15:123,352,816...123,503,126 		JBrowse link
G UFSP2 UFM1 specific peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:46,448,918...46,470,616
Ensembl chr15:46,448,904...46,470,572 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:854,605...861,969
Ensembl chr 6:858,888...861,604 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:182,357,597...182,407,792
Ensembl chr 1:182,357,607...182,407,782 		JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:6910481) UniProt PMID:6910481 NCBI chr 9:68,025,673...68,132,162 JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:19240864 RGD:7411612 NCBI chr 7:115,604,282...115,616,915
Ensembl chr 7:115,583,043...115,614,645 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (PMID:20110462)
(PMID:22228629) 		RGD
MGI		 PMID:12771515 PMID:20110462 PMID:22228629 RGD:724699 NCBI chr 2:149,072,652...149,079,529
Ensembl chr 2:149,071,703...149,079,499 		JBrowse link
G SPINK2 serine peptidase inhibitor Kazal type 2 acts_upstream_of_or_within ISO (PMID:21705336) MGI PMID:21705336 NCBI chr 8:55,982,377...55,989,592 JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 acts_upstream_of_or_within ISO (PMID:20179351) MGI PMID:20179351 NCBI chr 2:149,309,482...149,382,286
Ensembl chr 2:149,309,540...149,382,282 		JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chr 7:30,812,925...30,995,369
Ensembl chr 7:30,812,920...30,995,360 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within 		ISO
IEA 		(PMID:16173922), (PMID:18560357) UniProt
Ensembl		 PMID:16173922 PMID:18560357 GO_REF:0000107 NCBI chr 1:200,774,496...200,799,149
Ensembl chr 1:200,792,469...200,798,854 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,758,604...20,767,004
Ensembl chr 7:20,758,741...20,767,000 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:9,940,535...10,141,815
Ensembl chr18:9,861,792...10,135,065 		JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:53,681,798...53,693,034
Ensembl chr 3:53,674,509...53,692,928 		JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:112,698,865...112,710,305
Ensembl chr 4:112,701,088...112,703,581 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861) UniProt PMID:30683861 NCBI chr12:5,174,531...5,203,797
Ensembl chr12:5,176,926...5,199,272 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 6:81,523,510...81,526,925
Ensembl chr 6:81,522,742...81,530,436 		JBrowse link
G RPL23 ribosomal protein L23 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:23,279,965...23,285,538
Ensembl chr12:23,279,965...23,285,515 		JBrowse link
G RPL5 ribosomal protein L5 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr 4:124,359,786...124,367,612
Ensembl chr 4:124,358,594...124,367,645 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:131,258,709...131,263,285
Ensembl chr 3:131,258,722...131,263,256 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,879,081...75,896,279
Ensembl chr 2:75,879,058...75,896,277 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:113,500,001...113,628,064
Ensembl chr14:113,500,842...113,626,003 		JBrowse link
G SVIP small VCP interacting protein involved_in ISO PMID:17000876 ParkinsonsUK-UCL PMID:17000876 RGD:10047192 NCBI chr 2:36,703,757...36,714,018
Ensembl chr 2:36,703,790...36,714,934 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17237821) ParkinsonsUK-UCL PMID:17237821 NCBI chr  X:57,382,211...57,466,700
Ensembl chr  X:57,382,354...57,466,697 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,047,048...23,062,974
Ensembl chr 7:23,047,148...23,062,972 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,087,921...106,139,717
Ensembl chr 6:106,087,924...106,139,379 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,843,742...63,858,835
Ensembl chr 5:63,843,745...63,858,716 		JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:15,010,607...15,015,007
Ensembl chr 5:15,010,786...15,014,998 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC20 cell division cycle 20 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:167,886,266...167,890,587
Ensembl chr 6:167,886,270...167,890,583 		JBrowse link
G CDC20B cell division cycle 20B involved_in IBA GO_Central GO_REF:0000033 NCBI chr16:34,294,486...34,354,588
Ensembl chr16:34,294,272...34,349,242 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:75,122,599...75,164,134
Ensembl chr 2:75,121,835...75,146,835 		JBrowse link
positive regulation of aspartic-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in ISO (PMID:28453791) UniProt PMID:28453791 NCBI chr12:18,893,772...18,900,444
Ensembl chr12:18,893,770...18,900,446 		JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKIRIN2 akirin 2 ISO MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr 1:56,047,188...56,075,342
Ensembl chr 1:56,046,327...56,070,163 		JBrowse link
G PRELID1 PRELI domain containing 1 involved_in ISO (PMID:18945965) UniProt PMID:18945965 NCBI chr 2:80,641,844...80,646,390
Ensembl chr 2:80,641,845...80,653,670 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in ISO (PMID:12660785) UniProt PMID:12660785 NCBI chr 6:45,171,825...45,174,112
Ensembl chr 6:45,171,825...45,174,102 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:19079247) MGI PMID:19079247 NCBI chr 8:75,337,311...75,345,926
Ensembl chr 8:75,337,144...75,345,921 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in ISO (PMID:20666777) UniProt PMID:20666777 NCBI chr14:74,667,081...74,693,347
Ensembl chr14:74,666,624...74,693,281 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:113,611,566...113,645,835
Ensembl chr 7:113,608,783...113,645,841 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,756,897...23,768,659
Ensembl chr 7:23,756,897...23,768,666 		JBrowse link
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:124,456,999...124,484,923
Ensembl chr  X:124,457,001...124,484,743 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,901,171...18,913,427
Ensembl chr 6:18,901,297...18,913,424 		JBrowse link
G RNF185 ring finger protein 185 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,946,370...47,979,702
Ensembl chr14:47,951,481...47,979,699 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IEA
IBA 		InterPro
GO_Central
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:36,162,438...36,175,135
Ensembl chr12:36,162,444...36,174,851 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:35,634,619...35,705,795
Ensembl chr14:35,635,720...35,705,759 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,879,081...75,896,279
Ensembl chr 2:75,879,058...75,896,277 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,092,514...41,095,181
Ensembl chr 3:41,092,449...41,095,136 		JBrowse link
G TMEM259 transmembrane protein 259 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:77,393,577...77,402,266
Ensembl chr 2:77,393,611...77,402,262 		JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr 4:42,878,249...42,931,106
Ensembl chr 4:42,879,140...42,931,121 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:180,933,678...180,950,826
Ensembl chr 1:180,933,859...180,951,341 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:31,275,916...31,317,521
Ensembl chr10:31,275,868...31,317,516 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,948,062...48,951,392
Ensembl chr  X:48,948,389...48,950,263 		JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:117,700,080...117,826,951
Ensembl chr13:117,700,119...117,826,944 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in ISO (PMID:19911006) MGI PMID:19911006 NCBI chr 8:4,362,678...4,405,185
Ensembl chr 8:4,362,680...4,385,273 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:19911006) MGI PMID:19911006 NCBI chr14:46,011,239...46,016,526
Ensembl chr14:46,008,377...46,016,526 		JBrowse link
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:141,221,177...141,233,728
Ensembl chr14:141,221,198...141,232,306 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:9857183) BHF-UCL PMID:9857183 NCBI chr15:47,523,768...47,601,722
Ensembl chr15:47,523,771...47,601,710 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:25015123) ARUK-UCL PMID:25015123 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:19,289,385...19,355,606
Ensembl chr 7:19,291,174...19,346,619 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:18373975) BHF-UCL PMID:18373975
G NRDC nardilysin convertase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:160,299,101...160,388,511
Ensembl chr 6:160,299,131...160,388,502 		JBrowse link
G PACSIN3 protein kinase C and casein kinase substrate in neurons 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,380,297...15,389,893
Ensembl chr 2:15,381,707...15,389,887 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:85,921,524...85,968,887
Ensembl chr 7:85,921,594...85,968,888 		JBrowse link
G SH3D19 SH3 domain containing 19 involved_in ISO (PMID:15280379) BHF-UCL PMID:15280379 NCBI chr 8:77,689,393...77,876,412
Ensembl chr 8:77,689,716...77,876,664 		JBrowse link
G SNX33 sorting nexin 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:57,999,447...58,015,598
Ensembl chr 7:57,999,459...58,014,441 		JBrowse link
G SNX9 sorting nexin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,130,360...9,239,023
Ensembl chr 1:9,130,338...9,239,029 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,415 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:72,195,420...72,231,146
Ensembl chr 6:72,195,435...72,231,147 		JBrowse link
positive regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in IMP (PMID:23389627) AgBase PMID:23389627 NCBI chr 4:94,026,391...94,082,206
Ensembl chr 4:94,026,386...94,080,420 		JBrowse link
G MBP myelin basic protein involved_in ISO (PMID:22524708) CAFA PMID:22524708 NCBI chr 1:147,649,516...147,685,289
Ensembl chr 1:147,590,865...147,685,290 		JBrowse link
positive regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTXR1 ANTXR cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25572963) MGI PMID:25572963 NCBI chr 3:73,157,744...73,398,379
Ensembl chr 3:73,157,747...73,398,379 		JBrowse link
positive regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSH cathepsin H involved_in ISO (PMID:20435891) UniProt PMID:20435891 NCBI chr 7:48,084,882...48,106,072
Ensembl chr 7:48,083,572...48,106,072 		JBrowse link
G PRSS22 serine protease 22 involved_in ISO (PMID:15701722) UniProt PMID:15701722 NCBI chr 3:39,365,798...39,376,909
Ensembl chr 3:39,365,803...39,380,476 		JBrowse link
G RCN3 reticulocalbin 3 involved_in ISO (PMID:28939891) UniProt PMID:28939891 NCBI chr 6:54,599,347...54,611,275
Ensembl chr 6:54,599,719...54,611,272 		JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:111,588,721...111,635,064
Ensembl chr 1:111,588,306...111,635,059 		JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in ISS UniProt GO_REF:0000024 NCBI chr13:28,219,241...28,229,113
Ensembl chr13:28,219,500...28,229,096 		JBrowse link
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:69,385,879...69,401,664
Ensembl chr 6:69,385,879...69,401,151 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:80,527,451...80,544,835
Ensembl chr 2:80,527,446...80,544,828 		JBrowse link
G HPN hepsin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,608,076...44,628,044
Ensembl chr 6:44,608,071...44,628,049 		JBrowse link
G MELTF melanotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:133,094,869...133,122,092
Ensembl chr13:133,094,863...133,122,065 		JBrowse link
G PLGRKT plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within 		IEA
IBA 		InterPro
Ensembl
GO_Central		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:216,692,002...216,739,726
Ensembl chr 1:216,692,047...216,739,722 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 ISO RGD PMID:11027681 RGD:67924 NCBI chr13:72,196,219...72,246,514
Ensembl chr13:72,200,511...72,248,582 		JBrowse link
G S100A10 S100 calcium binding protein A10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:97,261,752...97,272,517
Ensembl chr 4:97,261,815...97,272,513 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:28,668,587...28,680,497
Ensembl chr 7:28,659,753...28,680,491 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,732,280...261,859,833
Ensembl chr 1:261,659,785...261,859,830 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:141,343,818...141,352,618
Ensembl chr 2:141,343,803...141,352,603 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 involved_in ISO (PMID:24709664) UniProt PMID:24709664 NCBI chr  X:120,361,232...120,400,282
Ensembl chr  X:120,361,367...120,399,831 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:197,979,749...197,980,974
Ensembl chr13:197,980,145...197,980,516 		JBrowse link
G NEURL3 neuralized E3 ubiquitin protein ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:46,741,636...46,751,553
Ensembl chr 3:46,742,971...46,751,547 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,402,781...18,404,411
Ensembl chr 3:18,402,935...18,511,087 		JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 ISO RGD PMID:12359729 RGD:7245486 NCBI chr 2:76,293,142...76,296,626
Ensembl chr 2:76,293,150...76,296,620 		JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:24,059,128...24,075,102
Ensembl chr12:24,059,124...24,076,109 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 involved_in IEA GOC GO_REF:0000108 NCBI chr 7:112,027,904...112,041,360
Ensembl chr 7:112,027,921...112,041,489 		JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 9:103,362,684...103,376,048
Ensembl chr 9:103,362,599...103,376,343 		JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 involved_in IEA GOC GO_REF:0000108 NCBI chr 2:15,185,482...15,191,189
Ensembl chr 2:15,166,306...15,193,047 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 involved_in IEA GOC GO_REF:0000108 NCBI chr 6:48,406,237...48,414,470
Ensembl chr 6:48,406,376...48,416,215 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 involved_in IEA GOC GO_REF:0000108 NCBI chr 1:182,329,070...182,354,959
Ensembl chr 1:182,328,521...182,354,958 		JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr 3:17,622,309...17,635,990
Ensembl chr 3:17,622,319...17,639,900 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:94,328,452...94,384,266
Ensembl chr 5:94,324,091...94,384,154 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:36,465,921...36,471,509
Ensembl chr 7:36,465,324...36,471,516 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within 		ISO (PMID:23512198)
(PMID:15937334) 		UniProt
MGI		 PMID:15937334 PMID:23512198
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:23152632) MGI PMID:23152632 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,654 		JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within ISO (PMID:17060449) MGI PMID:17060449 NCBI chr17:56,954,838...56,972,435 JBrowse link
G AXIN1 axin 1 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:41,344,908...41,393,999
Ensembl chr 3:41,337,071...41,393,997 		JBrowse link
G AXIN2 axin 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,298...12,343,200 		JBrowse link
G BAG2 BAG cochaperone 2 NOT|involved_in ISO (PMID:19228967) ARUK-UCL PMID:19228967 NCBI chr 7:28,668,587...28,680,497
Ensembl chr 7:28,659,753...28,680,491 		JBrowse link
G BBS7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr 8:102,213,455...102,259,204 JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:779,164...854,449
Ensembl chr 6:779,366...853,822 		JBrowse link
G CHFR checkpoint with forkhead and ring finger domains acts_upstream_of_or_within ISO (PMID:22285184) MGI PMID:22285184 NCBI chr14:22,654,462...22,683,970
Ensembl chr14:22,654,481...22,683,966 		JBrowse link
G CLU clusterin involved_in ISS
IBA
IEA 		UniProt
GO_Central
Ensembl		 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:117,913,504...118,114,268
Ensembl chr 9:117,915,443...118,114,259 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:150,612,845...150,662,431
Ensembl chr 2:150,612,077...150,662,284 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:768,856...794,495
Ensembl chr12:768,865...796,595 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:9,594,461...9,620,483
Ensembl chr 5:9,594,934...9,620,476 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:24,590,638...24,776,937
Ensembl chr16:24,590,645...24,646,122 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:60,367,168...60,376,986
Ensembl chr 2:60,367,166...60,376,958 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:191,263,449...191,284,973
Ensembl chr 1:191,263,448...191,284,967 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr15:121,319,897...121,335,927
Ensembl chr15:121,319,982...121,335,991 		JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:63,617,787...63,628,965
Ensembl chr 6:63,617,789...63,628,913 		JBrowse link
G FBXO22 F-box protein 22 involved_in
acts_upstream_of_or_within 		IBA
ISO 		(PMID:19319192) GO_Central
MGI		 PMID:19319192 GO_REF:0000033 NCBI chr 7:56,146,874...56,189,921
Ensembl chr 7:56,146,880...56,186,317 		JBrowse link
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:35,445,020...35,613,725
Ensembl chr14:35,444,281...35,575,705 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,596,130...52,598,166
Ensembl chr12:52,596,543...52,598,194 		JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within ISO (PMID:17189825) MGI PMID:17189825 NCBI chr 7:27,209,565...27,253,535
Ensembl chr 7:27,209,565...27,253,530 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:49,690,319...49,700,735
Ensembl chr 6:49,690,370...49,701,189 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in
acts_upstream_of_or_within 		IEA
IBA
ISO 		(PMID:22660580) Ensembl
GO_Central
MGI		 PMID:22660580 GO_REF:0000033 GO_REF:0000107 NCBI chr13:140,136,109...140,370,197
Ensembl chr13:140,136,158...140,369,569 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,785,863...44,787,303
Ensembl chr 6:44,784,160...44,787,305 		JBrowse link
G HSP70.2 heat shock protein 70.2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:23,925,929...23,927,854
Ensembl chr 7:23,925,732...23,928,180 		JBrowse link
G HSPBP1 HSPA (Hsp70) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:59,452,934...59,464,533
Ensembl chr 6:59,452,935...59,464,533 		JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within ISO (PMID:22660580) MGI PMID:22660580 NCBI chr 1:215,899,830...215,941,944
Ensembl chr 1:215,899,436...215,941,840 		JBrowse link
G KLHL40 kelch like family member 40 involved_in ISO (PMID:25940086) UniProt PMID:25940086 NCBI chr13:26,202,607...26,211,528
Ensembl chr13:26,202,677...26,211,522 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:71,800,337...71,945,828
Ensembl chr 5:71,800,225...71,945,828 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO (PMID:29153991) UniProt PMID:29153991 NCBI chr14:88,988,914...89,108,875
Ensembl chr14:88,988,949...89,108,874 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,376...78,399,100 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,105,717...33,137,602
Ensembl chr 5:33,105,759...33,137,739 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:79,400,323...79,419,779
Ensembl chr16:79,400,997...79,419,759 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:53,443,453...53,451,707
Ensembl chr 6:53,443,385...53,452,017 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:5,899,566...5,928,981
Ensembl chr18:5,899,568...5,928,884 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in ISO (PMID:27588481) UniProt PMID:27588481 NCBI chr 1:222,114,314...222,122,337 JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 1:222,119,862...222,120,725 JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:138,646,626...138,670,166
Ensembl chr 8:138,646,625...138,669,115 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:165,957,114...166,087,242
Ensembl chr 1:165,957,132...166,087,239 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,537,814...22,550,901
Ensembl chr 3:22,537,831...22,552,380 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:18723513 RGD:7241135 NCBI chr16:37,299,116...37,305,114
Ensembl chr16:37,299,119...37,305,114 		JBrowse link
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:166,528,760...166,533,734
Ensembl chr 6:166,528,765...166,533,731 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:73,707,026...73,826,529
Ensembl chr 5:73,707,050...73,826,430 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:88,540,261...88,548,593
Ensembl chr  X:88,540,376...88,548,560 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 2:57,280,192...57,284,846
Ensembl chr 2:57,279,857...57,284,849 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:66,090,089...66,096,477
Ensembl chr 2:66,084,668...66,096,329 		JBrowse link
G RBX1 ring-box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:7,500,492...7,515,388
Ensembl chr 5:7,500,490...7,515,370 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:71,155,388...71,182,020
Ensembl chr 8:71,162,840...71,181,919 		JBrowse link
G RNF180 ring finger protein 180 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr16:42,686,225...42,951,928
Ensembl chr16:42,723,065...42,953,592 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:35,634,619...35,705,795
Ensembl chr14:35,635,720...35,705,759 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:20,420,618...20,559,273
Ensembl chr14:20,420,618...20,559,271 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:147,290,322...147,413,151
Ensembl chr 2:147,290,579...147,413,143 		JBrowse link
G SH3RF3 SH3 domain containing ring finger 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:47,128,448...47,339,569
Ensembl chr 3:47,133,532...47,339,541 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,682,427...47,703,408
Ensembl chr 6:47,682,429...47,703,384 		JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:74,568,539...74,577,774
Ensembl chr 2:74,568,493...74,577,772 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:184,379,017...184,398,902
Ensembl chr 1:184,379,086...184,398,898 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:93,777,402...93,925,859
Ensembl chr 3:93,783,964...93,925,863 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,092,514...41,095,181
Ensembl chr 3:41,092,449...41,095,136 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:105,820,237...105,850,099
Ensembl chr15:105,818,858...105,850,233 		JBrowse link
G SUMO2 small ubiquitin like modifier 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,116,694...6,130,089
Ensembl chr12:6,116,606...6,130,350 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:15053879) BHF-UCL PMID:15053879 NCBI chr  X:57,382,211...57,466,700
Ensembl chr  X:57,382,354...57,466,697 		JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:74,930,655...74,970,599
Ensembl chr13:74,930,655...74,972,763 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:14,289,739...14,298,119
Ensembl chr 4:14,289,751...14,297,663 		JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:124,170,677...124,196,253
Ensembl chr 3:124,172,098...124,196,210 		JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:34,808,273...34,819,592
Ensembl chr17:34,807,582...34,816,451 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 4:79,621,343...79,652,502
Ensembl chr 4:79,621,349...79,652,471 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:63,843,742...63,858,835
Ensembl chr 5:63,843,745...63,858,716 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:235,854,532...235,869,712
Ensembl chr 1:235,851,206...235,869,634 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:269,088,696...269,121,895
Ensembl chr 1:269,090,159...269,108,256 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:756,427...776,028
Ensembl chr 3:756,429...775,983 		JBrowse link
G ZYG11B zyg-11 family member B, cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,407,921...159,480,617
Ensembl chr 6:159,407,934...159,480,586 		JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPTL8 angiopoietin like 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:69,951,556...69,954,223
Ensembl chr 2:69,952,581...69,954,220 		JBrowse link
G ASTL astacin like metalloendopeptidase involved_in ISO (PMID:22472438) UniProt PMID:22472438 NCBI chr 3:47,058,104...47,071,681
Ensembl chr 3:47,059,040...47,070,664 		JBrowse link
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:28,668,587...28,680,497
Ensembl chr 7:28,659,753...28,680,491 		JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:161,320,627...161,556,539
Ensembl chr 1:161,321,273...161,556,537 		JBrowse link
G CNTN2 contactin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:65,737,488...65,776,412
Ensembl chr 9:65,736,740...65,776,396 		JBrowse link
G CTNND1 catenin delta 1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr 2:13,143,604...13,209,251
Ensembl chr 2:13,154,338...13,209,250 		JBrowse link
G FUZ fuzzy planar cell polarity protein acts_upstream_of_or_within ISO (PMID:19877275) MGI PMID:19877275 NCBI chr 6:54,823,680...54,830,425
Ensembl chr 6:54,823,668...54,829,506 		JBrowse link
G LOC100157391 mitochondrial import inner membrane translocase subunit Tim23 ISO RGD PMID:9756630 RGD:13463485 NCBI chr14:90,480,955...90,506,134
Ensembl chr14:90,481,070...90,506,642 		JBrowse link
G MBL2 mannose binding lectin 2 ISO Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr14:97,103,926...97,107,635
Ensembl chr14:97,102,823...97,108,083 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:14668206 RGD:1582606 NCBI chr 7:76,174,502...76,185,931
Ensembl chr 7:76,172,971...76,185,928 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:79,400,323...79,419,779
Ensembl chr16:79,400,997...79,419,759 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in ISO (PMID:15882992) ARUK-UCL PMID:15882992 NCBI chr 3:107,358,117...107,389,557 JBrowse link
G RHBDD1 rhomboid domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:128,346,315...128,499,151
Ensembl chr15:128,346,373...128,469,213 		JBrowse link
G SPON1 spondin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:44,967,982...45,299,677
Ensembl chr 2:44,967,986...45,299,677 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:40,470,970...40,524,862
Ensembl chr17:40,471,009...40,524,860 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A ISO RGD PMID:9756630 RGD:13463485 NCBI chr10:24,200,345...24,211,790
Ensembl chr10:24,200,368...24,211,786 		JBrowse link
G TNP1 transition protein 1 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr15:119,037,492...119,038,099
Ensembl chr15:119,037,496...119,038,105 		JBrowse link
G TNP2 transition protein 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr 3:31,868,517...31,871,530
Ensembl chr 3:31,870,068...31,871,702 		JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,307,008...261,372,848 		JBrowse link
G MYH9 myosin heavy chain 9 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472 		JBrowse link
positive regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPH aspartate beta-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:71,902,891...72,107,047
Ensembl chr 4:71,903,318...72,107,044 		JBrowse link
G AURKAIP1 aurora kinase A interacting protein 1 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:63,656,120...63,657,568
Ensembl chr 6:63,656,119...63,657,472 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:29,808,849...29,815,345
Ensembl chr 7:29,808,849...29,815,318 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:112,398,764...112,588,041
Ensembl chr14:112,398,868...112,588,037 		JBrowse link
G CAPN3 calpain 3 involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:128,960,117...129,013,508
Ensembl chr 1:128,960,118...129,013,546 		JBrowse link
G CASP8 caspase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468 		JBrowse link
G CD46 CD46 molecule, complement regulatory protein ISO RGD PMID:15215199 RGD:2293559 NCBI chr 9:135,025,439...135,078,910 JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24093776 RGD:11570550 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035 		JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:166,107,895...166,126,054
Ensembl chr 1:166,107,228...166,126,808 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:65,852,584...66,001,576
Ensembl chr16:65,852,588...66,001,559 		JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:16973938 RGD:2289912 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760 		JBrowse link
G FADD Fas associated via death domain involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:3,191,718...3,194,820
Ensembl chr 2:3,185,675...3,194,818 		JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 involved_in ISO (PMID:16885022) UniProt PMID:16885022 NCBI chr16:52,212,401...52,337,893
Ensembl chr16:52,212,607...52,337,913 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:80,841,536...80,853,791
Ensembl chr 2:80,841,536...80,853,796 		JBrowse link
G HDAC2 histone deacetylase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:79,867,713...79,901,597
Ensembl chr 1:79,863,094...79,901,585 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9987077 RGD:10059370 NCBI chr 9:49,982,278...49,986,760
Ensembl chr 9:49,982,284...49,990,508 		JBrowse link
G IST1 IST1 factor associated with ESCRT-III involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:14,868,859...14,910,679
Ensembl chr 6:14,836,752...14,911,311 		JBrowse link
G OGA O-GlcNAcase ISO Degradation of calmodulin-dependent protein kinase II and alpha fodrin (RGD: 621714). RGD PMID:17573462 RGD:2305953 NCBI chr14:112,822,494...112,851,215
Ensembl chr14:112,822,499...112,851,203 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in ISS
IEA 		UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:57,521,091...57,558,467
Ensembl chr  X:57,521,098...57,558,515 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,301,254...26,317,046
Ensembl chr 1:26,301,252...26,317,868 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:22,537,814...22,550,901
Ensembl chr 3:22,537,831...22,552,380 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:41,092,514...41,095,181
Ensembl chr 3:41,092,449...41,095,136 		JBrowse link
G TBC1D10A TBC1 domain family member 10A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:47,269,087...47,301,540
Ensembl chr14:47,269,092...47,301,753 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:257,051,421...257,066,911
Ensembl chr 1:257,054,228...257,066,909 		JBrowse link
positive regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:85,307,242...85,309,211
Ensembl chr 6:85,307,189...85,309,215 		JBrowse link
G CTSC cathepsin C involved_in ISO PMID:18307834 ParkinsonsUK-UCL PMID:18307834 RGD:8661625 NCBI chr 9:21,726,628...21,761,796
Ensembl chr 9:21,722,036...21,761,516 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:94,583,905...94,606,689
Ensembl chr 4:94,584,134...94,609,745 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:87,363,911...87,390,371
Ensembl chr 6:87,363,911...87,390,347 		JBrowse link
G RGN regucalcin ISO RGD PMID:1513338 RGD:9590188 NCBI chr  X:41,725,660...41,749,736
Ensembl chr  X:41,726,526...41,749,381 		JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:63,638,589...63,698,931
Ensembl chr 1:63,638,596...63,700,476 		JBrowse link
positive regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:2972794) UniProt PMID:2972794 NCBI chr 9:68,025,673...68,132,162 JBrowse link
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGBL4 AGBL carboxypeptidase 4 acts_upstream_of_or_within ISO (PMID:29593216) MGI PMID:29593216 NCBI chr 6:161,953,495...163,216,282 JBrowse link
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr10:29,440,150...29,590,457
Ensembl chr10:29,440,145...29,590,454 		JBrowse link
G ATXN3 ataxin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:113,611,566...113,645,835
Ensembl chr 7:113,608,783...113,645,841 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in 		IEA
ISO 		PMID:10228155 Ensembl
BHF-UCL		 PMID:10228155 GO_REF:0000107 RGD:8553327 NCBI chr 3:41,344,908...41,393,999
Ensembl chr 3:41,337,071...41,393,997 		JBrowse link
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:124,456,999...124,484,923
Ensembl chr  X:124,457,001...124,484,743 		JBrowse link
G CCDC22 coiled-coil domain containing 22 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:43,285,232...43,303,865
Ensembl chr  X:43,285,246...43,303,864 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 NOT|involved_in ISO (PMID:16173922) UniProt PMID:16173922 NCBI chr12:24,224,262...24,234,468
Ensembl chr12:24,224,263...24,234,467 		JBrowse link
G CLU clusterin involved_in IEA
ISS 		Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:11,336,585...11,352,569
Ensembl chr14:11,336,595...11,349,764 		JBrowse link
G DISC1 DISC1 scaffold protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:58,606,441...58,963,954
Ensembl chr14:58,606,464...58,963,563 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,386...112,330,046 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within ISO (PMID:19319192) MGI PMID:19319192 NCBI chr 7:56,146,874...56,189,921
Ensembl chr 7:56,146,880...56,186,317 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:76,482,027...76,699,354
Ensembl chr 8:76,482,844...76,699,348 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,901,171...18,913,427
Ensembl chr 6:18,901,297...18,913,424 		JBrowse link
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:33,198,295...33,319,477
Ensembl chr 1:33,198,301...33,319,399 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:87,363,911...87,390,371
Ensembl chr 6:87,363,911...87,390,347 		JBrowse link
G MTOR mechanistic target of rapamycin kinase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in ISO (PMID:21241890) BHF-UCL PMID:21241890 NCBI chr14:99,929,590...100,021,619 JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (PMID:18206965) UniProt PMID:18206965 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:15,157,571...15,182,520
Ensembl chr 4:15,154,331...15,197,511 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,879,081...75,896,279
Ensembl chr 2:75,879,058...75,896,277 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:6,037,732...6,142,569
Ensembl chr 3:6,037,741...6,142,575 		JBrowse link
G SUMO3 small ubiquitin like modifier 3 acts_upstream_of_or_within ISO (PMID:18644859) MGI PMID:18644859 NCBI chr13:207,475,303...207,484,362
Ensembl chr13:207,476,441...207,484,250 		JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,093,275...17,099,204
Ensembl chr 3:17,090,116...17,099,020 		JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:39,811,803...39,828,450
Ensembl chr 3:39,810,606...39,828,395 		JBrowse link
G TRIM67 tripartite motif containing 67 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:59,260,070...59,303,244
Ensembl chr14:59,260,065...59,302,591 		JBrowse link
G VCP valosin containing protein ISO RGD PMID:16103111 RGD:1599730 NCBI chr 1:235,854,532...235,869,712
Ensembl chr 1:235,851,206...235,869,634 		JBrowse link
positive regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TANK TRAF family member associated NFKB activator involved_in ISO (PMID:25861989) UniProt PMID:25861989 NCBI chr15:67,970,972...68,048,681
Ensembl chr15:67,952,173...68,048,963 		JBrowse link
regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2ML1 alpha-2-macroglobulin like 1 involved_in ISO (PMID:16298998) UniProt PMID:16298998 NCBI chr 5:62,603,260...62,648,170
Ensembl chr 5:62,603,260...62,648,201 		JBrowse link
regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 6:18,901,171...18,913,427
Ensembl chr 6:18,901,297...18,913,424 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:31,726,668...31,738,135
Ensembl chr13:31,726,672...31,737,981 		JBrowse link
regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSPAN15 tetraspanin 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:72,501,289...72,555,084
Ensembl chr14:72,468,914...72,555,080 		JBrowse link
G TSPAN17 tetraspanin 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:81,256,989...81,276,638
Ensembl chr 2:81,260,281...81,276,636 		JBrowse link
G TSPAN5 tetraspanin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:121,657,320...121,843,296
Ensembl chr 8:121,657,325...121,843,242 		JBrowse link
regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHBDF2 rhomboid 5 homolog 2 acts_upstream_of_or_within ISO (PMID:29897333) MGI PMID:29897333 NCBI chr12:5,008,534...5,036,278
Ensembl chr12:5,010,178...5,036,255 		JBrowse link
regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC100519023 small vasohibin-binding protein involved_in ISO (PMID:31171830), (PMID:31235910), (PMID:31235911), (PMID:31270470) UniProt PMID:31171830 PMID:31235910 PMID:31235911 PMID:31270470 NCBI chr 4:107,654,578...107,655,087 JBrowse link
regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (PMID:17349656) MGI PMID:17349656 NCBI chr18:29,648,120...29,682,451
Ensembl chr18:29,649,992...29,682,465 		JBrowse link
regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,292...51,375,330 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr14:112,398,764...112,588,041
Ensembl chr14:112,398,868...112,588,037 		JBrowse link
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr 6:102,333,088...103,199,841
Ensembl chr 6:102,642,677...103,199,837 		JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:116,331,217...116,431,673
Ensembl chr 1:116,332,630...116,430,984 		JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:19,806,363...19,893,350
Ensembl chr 1:19,806,765...19,893,339 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:31,916,269...31,917,337
Ensembl chr13:31,916,246...31,917,433 		JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:24,303,381...24,316,765
Ensembl chr12:24,303,399...24,316,763 		JBrowse link
G NUDT15 nudix hydrolase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:19,572,963...19,584,565
Ensembl chr11:19,572,644...19,584,528 		JBrowse link
G PITHD1 PITH domain containing 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:81,590,868...81,598,874
Ensembl chr 6:81,591,018...81,598,868 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 3:39,849,579...39,899,455
Ensembl chr 3:39,849,609...39,899,455 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551 		JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,107,379...68,208,884
Ensembl chr15:68,162,532...68,208,883 		JBrowse link
G PSME1 proteasome activator subunit 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:75,161,830...75,164,531
Ensembl chr 7:75,160,766...75,164,810 		JBrowse link
G PSME2 proteasome activator subunit 2 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:75,154,570...75,157,871
Ensembl chr 7:75,153,965...75,157,870 		JBrowse link
G PSME3 proteasome activator subunit 3 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr12:20,028,112...20,035,865
Ensembl chr12:20,028,112...20,035,557 		JBrowse link
G RHBDF1 rhomboid 5 homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:41,548,440...41,567,596
Ensembl chr 3:41,560,915...41,567,593 		JBrowse link
G TMF1 TATA element modulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:50,442,017...50,477,363
Ensembl chr13:50,444,256...50,477,291 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:59,171,258...59,172,841
Ensembl chr12:59,171,289...59,172,841 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:725,688...761,633
Ensembl chr10:725,561...763,985 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:106,087,921...106,139,717
Ensembl chr 6:106,087,924...106,139,379 		JBrowse link
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARAF A-Raf proto-oncogene, serine/threonine kinase involved_in IEA
ISS 		Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr  X:42,078,202...42,090,250
Ensembl chr  X:42,078,206...42,090,250 		JBrowse link
G CLEC16A C-type lectin domain containing 16A involved_in ISO (PMID:36822331) DisProt PMID:36822331 NCBI chr 3:31,938,133...32,158,343
Ensembl chr 3:31,938,135...32,158,320 		JBrowse link
G COMMD1 copper metabolism domain containing 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:79,770,315...79,913,969
Ensembl chr 3:79,770,463...79,913,975 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:60,367,168...60,376,986
Ensembl chr 2:60,367,166...60,376,958 		JBrowse link
G DESI1 desumoylating isopeptidase 1 involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 5:6,929,302...6,954,040
Ensembl chr 5:6,929,297...6,954,037 		JBrowse link
G FOXF2 forkhead box F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:715,001...719,781
Ensembl chr 7:715,001...720,104 		JBrowse link
G GLMN glomulin, FKBP associated protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 4:124,773,957...124,813,336
Ensembl chr 4:124,773,980...124,813,335 		JBrowse link
G GNA12 G protein subunit alpha 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:2,002,494...2,105,937
Ensembl chr 3:2,004,471...2,105,952 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:66,090,089...66,096,477
Ensembl chr 2:66,084,668...66,096,329 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:248,447,991...248,493,651
Ensembl chr 1:248,448,265...248,493,647 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:30,887,784...30,961,685
Ensembl chr 8:30,887,830...30,963,762 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:93,976,386...93,994,830
Ensembl chr 4:93,976,451...93,994,828 		JBrowse link
G UFL1 UFM1 specific ligase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:63,638,589...63,698,931
Ensembl chr 1:63,638,596...63,700,476 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:14,997,377...15,013,928
Ensembl chr 5:14,997,381...15,003,567 		JBrowse link
G XPO1 exportin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:80,255,016...80,300,260
Ensembl chr 3:80,255,146...80,300,327 		JBrowse link
G ZNF416 zinc finger protein 416 involved_in ISO PMID:33249983
(PMID:33249983) 		UniProt PMID:33249983 RGD:329955556 NCBI chr 6:62,039,477...62,043,177 JBrowse link
regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,433,564...18,450,296
Ensembl chr 3:18,433,836...18,450,290 		JBrowse link
G CWH43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:38,869,156...38,944,845
Ensembl chr 8:38,869,138...38,943,669 		JBrowse link
G IFT52 intraflagellar transport 52 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr17:46,209,956...46,246,696
Ensembl chr17:46,210,150...46,246,674 		JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (PMID:15930098)
(PMID:16254602) 		MGI PMID:15930098 PMID:16254602 NCBI chr11:943,444...1,025,617
Ensembl chr11:943,469...1,025,613 		JBrowse link
G INPP5B inositol polyphosphate-5-phosphatase B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:93,885,471...93,944,398
Ensembl chr 6:93,885,465...93,944,342 		JBrowse link
G LDLRAD3 low density lipoprotein receptor class A domain containing 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:24,875,379...25,155,314
Ensembl chr 2:24,875,380...25,138,873 		JBrowse link
G NOTCH4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) MGI PMID:24667410 NCBI chr 7:24,231,293...24,256,281
Ensembl chr 7:24,231,293...24,256,281 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551 		JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:129,520,397...129,636,207
Ensembl chr 6:129,520,376...129,635,733 		JBrowse link
G PRSS37 serine protease 37 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:8,112,288...8,119,176
Ensembl chr18:8,111,692...8,118,953 		JBrowse link
G RFX4 regulatory factor X4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:13,590,845...13,758,913
Ensembl chr 5:13,590,851...13,758,567 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:15,157,571...15,182,520
Ensembl chr 4:15,154,331...15,197,511 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) MGI PMID:16585392 NCBI chr 1:2,203,825...2,522,604
Ensembl chr 1:2,203,606...2,522,599 		JBrowse link
regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:33,198,295...33,319,477
Ensembl chr 1:33,198,301...33,319,399 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:16,274,955...16,320,980
Ensembl chr 1:16,274,970...16,320,604 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr18:5,899,566...5,928,981
Ensembl chr18:5,899,568...5,928,884 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192 		JBrowse link
G TMEM168 transmembrane protein 168 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr18:32,928,104...32,960,884
Ensembl chr18:32,927,748...32,957,960 		JBrowse link
G UBE3A ubiquitin protein ligase E3A involved_in IEA
IBA 		Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:141,887,179...142,001,595
Ensembl chr 1:141,887,227...141,995,003 		JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme involved_in ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696 PMID:11799113 NCBI chr 7:53,455,634...53,472,791
Ensembl chr 7:53,460,017...53,472,787 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18944
    cellular process 18486
      metabolic process 11686
        macromolecule metabolic process 9777
          protein metabolic process 4436
            proteolysis 1484
              regulation of proteolysis 407
                negative regulation of proteolysis + 150
                positive regulation of proteolysis + 217
                regulation of membrane protein ectodomain proteolysis + 27
                regulation of peptidase activity + 41
                regulation of protein processing + 64
                regulation of proteolysis involved in protein catabolic process + 239
Path 2
Term Annotations click to browse term
  biological_process 18944
    biological regulation 13005
      regulation of biological process 12624
        regulation of cellular process 12283
          regulation of metabolic process 6322
            regulation of primary metabolic process 5168
              regulation of protein metabolic process 1858
                regulation of proteolysis 407
                  negative regulation of proteolysis + 150
                  positive regulation of proteolysis + 217
                  regulation of membrane protein ectodomain proteolysis + 27
                  regulation of peptidase activity + 41
                  regulation of protein processing + 64
                  regulation of proteolysis involved in protein catabolic process + 239
paths to the root