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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteolysis
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Accession:GO:0030162 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: regulation of peptidolysis

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regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2CD3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:65,282,311...65,436,007
Ensembl chr 1:65,282,318...65,435,834 		JBrowse link
G GSAP gamma-secretase activating protein involved_in ISO (PMID:20811458) UniProt PMID:20811458 NCBI chr21:71,513,271...71,735,228 JBrowse link
G GSAP gamma-secretase activating protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr21:71,513,149...71,601,376 JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:5,536,556...5,589,522
Ensembl chr15:5,536,610...5,590,825 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 ISO positive regulation of cysteine-type endopeptidase activity RGD PMID:18278556 RGD:401965430 NCBI chr 2:13,385,681...13,459,180
Ensembl chr 2:13,387,727...13,459,105 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:80,735,234...80,872,104
Ensembl chr24:80,789,699...80,866,480 		JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in ISO (PMID:27179792) ARUK-UCL PMID:27179792 NCBI chr10:3,112,605...3,173,522
Ensembl chr10:3,113,868...3,173,620 		JBrowse link
G TMED10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within ISO (PMID:16641999) MGI PMID:16641999 NCBI chr24:52,349,869...52,392,436
Ensembl chr24:52,346,815...52,392,525 		JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRB2 crumbs cell polarity complex component 2 involved_in ISO (PMID:20299451) UniProt PMID:20299451 NCBI chr12:14,756,897...14,782,131
Ensembl chr12:14,758,618...14,779,514 		JBrowse link
G FETUB fetuin B involved_in ISO (PMID:23562279) UniProt PMID:23562279 NCBI chr15:2,773,057...2,790,944
Ensembl chr15:2,770,927...2,790,248 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in ISO (PMID:22832495) UniProt PMID:22832495 NCBI chr11:6,569,029...6,572,877 JBrowse link
G LOC103244145 serpin B8 involved_in ISO (PMID:8530382) UniProt PMID:8530382 NCBI chr18:15,766,510...15,787,350
Ensembl chr18:15,765,671...15,787,370 		JBrowse link
G RENBP renin binding protein ISO RGD PMID:11926999 RGD:727355 NCBI chr  X:128,359,313...128,369,070
Ensembl chr  X:128,359,396...128,368,581 		JBrowse link
G SERPINB1 serpin family B member 1 involved_in ISO (PMID:30692621) UniProt PMID:30692621 NCBI chr17:69,318,919...69,327,733
Ensembl chr17:69,319,302...69,328,865 		JBrowse link
G SERPINB13 serpin family B member 13 involved_in ISO (PMID:12504904) UniProt PMID:12504904 NCBI chr18:16,163,247...16,175,953
Ensembl chr18:16,165,054...16,173,438 		JBrowse link
G SERPINB9 serpin family B member 9 involved_in ISO (PMID:21795594) UniProt PMID:21795594 NCBI chr17:69,258,377...69,272,954
Ensembl chr17:69,259,258...69,272,501 		JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:10717410 RGD:8547889 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202 		JBrowse link
G SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 involved_in ISO (PMID:11751414) UniProt PMID:11751414 NCBI chr 7:113,040,250...113,531,535 JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in ISO (PMID:3903517) UniProt PMID:3903517
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:68,805,354...68,824,017
Ensembl chr 1:68,807,025...68,824,792 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,534,398...2,562,306
Ensembl chr 6:2,534,376...2,548,604 		JBrowse link
G SVIP small VCP interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:42,185,115...42,193,121
Ensembl chr 1:42,185,121...42,195,006 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:11,228,944...11,231,549
Ensembl chr 1:11,228,135...11,231,459 		JBrowse link
G UBXN2A UBX domain protein 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:83,672,327...83,722,961
Ensembl chr14:83,673,282...83,703,633 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:59,568,934...59,622,467
Ensembl chr18:59,568,844...59,621,476 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:76,660,926...76,805,153
Ensembl chr 2:76,662,159...76,791,688 		JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:22,590,389...22,595,877
Ensembl chr25:22,590,962...22,594,836 		JBrowse link
G LOC103231892 metalloproteinase inhibitor 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:44,759,412...44,763,243
Ensembl chr  X:44,760,531...44,765,571 		JBrowse link
G LRIG2 leucine rich repeats and immunoglobulin like domains 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:20,523,713...20,575,577
Ensembl chr20:20,524,352...20,574,224 		JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:30,048,941...30,168,816
Ensembl chr12:30,083,128...30,171,473 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in ISO (PMID:12714508) UniProt PMID:12714508
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:48,134,133...48,140,870
Ensembl chr22:48,134,637...48,140,600 		JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in ISO (PMID:9573338) UniProt PMID:9573338
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in ISO (PMID:9573338) UniProt PMID:9573338 NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471 		JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAST calpastatin acts_upstream_of_or_within ISO (PMID:21849499) MGI PMID:21849499 NCBI chr 4:90,496,867...90,607,019
Ensembl chr 4:90,497,754...90,605,481 		JBrowse link
G ECM1 extracellular matrix protein 1 involved_in ISO (PMID:16512877) UniProt PMID:16512877
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within ISO (PMID:15509762), (PMID:18398001) MGI PMID:15509762 PMID:18398001 NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513 		JBrowse link
G SMR3B submaxillary gland androgen regulated protein 3B involved_in ISO PMID:12835417 UniProt PMID:12835417 RGD:8553855 NCBI chr 7:18,892,457...18,900,365 JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (PMID:3428272) MGI PMID:3428272 NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814 		JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPB2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chr 3:24,108,854...24,161,669
Ensembl chr 3:24,109,416...24,161,408 		JBrowse link
G CTSZ cathepsin Z involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,135,729...5,146,063
Ensembl chr 2:5,135,770...5,145,630 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:1,392,562...1,404,574
Ensembl chr16:1,392,571...1,404,636 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,173,063...26,185,456
Ensembl chr12:26,173,096...26,189,845 		JBrowse link
G F8A1 coagulation factor VIII associated 1 involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:129,131,267...129,133,575 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:61,053,283...61,078,675
Ensembl chr 5:61,053,262...61,066,083 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,914,261...27,921,666
Ensembl chr17:27,911,013...27,921,251 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in ISO (PMID:25681212) ParkinsonsUK-UCL PMID:25681212 NCBI chr15:6,245,146...6,285,481 JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:45,121,817...45,178,547
Ensembl chr10:45,121,538...45,177,271 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr  X:57,906,868...58,291,358
Ensembl chr  X:57,911,555...58,290,900 		JBrowse link
G PRKCG protein kinase C gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:46,574,560...46,600,329
Ensembl chr 6:46,575,439...46,600,364 		JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in ISO (PMID:29934401) UniProt PMID:29934401 NCBI chr 5:43,104,475...43,137,745 JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:55,373,939...55,415,928
Ensembl chr 2:55,376,171...55,415,893 		JBrowse link
G SCO1 SCO1, cytochrome c oxidase assembly protein acts_upstream_of_or_within ISO (PMID:25683716) MGI PMID:25683716 NCBI chr16:10,021,480...10,036,920 JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in ISO (PMID:25088257) ParkinsonsUK-UCL PMID:25088257 NCBI chr22:10,510,554...10,523,576
Ensembl chr22:10,510,423...10,523,487 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:81,496,664...81,502,969 JBrowse link
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:18678708) UniProt PMID:18678708
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:37,527,411...37,540,405
Ensembl chr23:37,527,875...37,541,259 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:20,685,482...20,700,424
Ensembl chr 8:20,686,504...20,699,707 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (PMID:24949970) MGI PMID:24949970 NCBI chr 5:10,420,866...10,658,370
Ensembl chr 5:10,420,931...10,658,507 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr 2:55,982,259...56,047,023 JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,093,320...44,133,352
Ensembl chr 5:44,093,215...44,133,335 		JBrowse link
G CSNK2B casein kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:40,354,520...40,359,136
Ensembl chr17:40,352,367...40,358,401 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:33,846,591...33,879,770
Ensembl chr 2:33,860,439...33,880,101 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in ISO (PMID:32269044) FlyBase PMID:32269044 NCBI chr 8:111,283,184...111,390,835 JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in ISO (PMID:15313915) UniProt PMID:15313915 NCBI chr22:21,006,010...22,474,056 JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:13,136,647...13,155,259
Ensembl chr 6:13,136,624...13,142,002 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,159,770...46,168,831
Ensembl chr17:46,156,685...46,164,649 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:27,914,261...27,921,666
Ensembl chr17:27,911,013...27,921,251 		JBrowse link
G KLHL40 kelch like family member 40 acts_upstream_of_or_within
involved_in 		ISO
IEA 		(PMID:24960163) MGI
TreeGrafter		 PMID:24960163 GO_REF:0000118 NCBI chr22:4,141,759...4,149,158
Ensembl chr22:4,142,192...4,148,710 		JBrowse link
G LOC103221857 E3 ubiquitin-protein ligase TRIM39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,142,185...42,159,256
Ensembl chr17:42,142,073...42,158,764 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (PMID:26609151) ARUK-UCL PMID:26609151 NCBI chr26:39,469,013...39,489,666
Ensembl chr26:39,468,222...39,489,613 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (PMID:23695157) MGI PMID:23695157 NCBI chr  X:125,151,279...125,250,816
Ensembl chr  X:125,174,289...125,249,588 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:34,351,845...34,423,152
Ensembl chr 5:34,347,979...34,422,887 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:41,058,199...41,070,220
Ensembl chr 6:41,057,906...41,071,202 		JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,351,047...61,393,541
Ensembl chr  X:61,351,054...61,394,305 		JBrowse link
G PANO1 proapoptotic nucleolar protein 1 involved_in ISO (PMID:22094112) UniProt PMID:22094112 NCBI chr 1:600,919...602,589 JBrowse link
G PARK7 Parkinsonism associated deglycase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr20:123,776,084...123,808,031
Ensembl chr20:123,776,297...123,798,434 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 8:25,921,124...25,943,349
Ensembl chr 8:25,921,133...25,943,062 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:127,201,612...127,275,378
Ensembl chr 8:127,201,658...127,272,501 		JBrowse link
G RGS19 regulator of G protein signaling 19 involved_in ISO (PMID:11546783) BHF-UCL PMID:11546783 NCBI chr 2:166,690...173,324
Ensembl chr 2:169,758...173,409 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (PMID:21804542) UniProt PMID:21804542 NCBI chr20:108,982,781...108,987,667
Ensembl chr20:108,981,723...108,987,734 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:33,327,516...33,397,463
Ensembl chr22:33,331,290...33,397,362 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (PMID:17981124) MGI PMID:17981124 NCBI chr11:44,272,371...44,334,787 JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr21:123,929,937...123,942,451
Ensembl chr21:123,932,900...123,942,395 		JBrowse link
G SMARCC1 SWI/SNF related BAF chromatin remodeling complex subunit C1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr22:8,987,936...9,167,689
Ensembl chr22:8,987,012...9,134,946 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 4:65,451,038...65,455,896 JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:58,662,284...58,800,838
Ensembl chr16:58,660,126...58,797,786 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO (PMID:31537781) MGI PMID:31537781 NCBI chr 1:109,912,976...109,917,097 JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr 1:109,913,430...109,917,024 JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:11,228,944...11,231,549
Ensembl chr 1:11,228,135...11,231,459 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:36,362,340...36,415,550
Ensembl chr25:36,364,027...36,414,762 		JBrowse link
G USP26 ubiquitin specific peptidase 26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:108,187,526...108,275,829
Ensembl chr  X:108,187,858...108,190,605 		JBrowse link
G USP38 ubiquitin specific peptidase 38 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:90,049,643...90,087,152
Ensembl chr 7:90,049,638...90,089,110 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in ISO (PMID:37534934) UniProt PMID:37534934 NCBI chr11:6,885,401...6,899,983
Ensembl chr11:6,885,311...6,898,442 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:8,470,137...8,540,736
Ensembl chr 5:8,469,230...8,540,770 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:38,255,414...38,402,855
Ensembl chr  X:38,256,008...38,403,323
Ensembl chr  Y:38,256,008...38,403,323 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:28,131,774...28,222,501
Ensembl chr 9:28,131,769...28,219,134 		JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,838,103...43,843,715
Ensembl chr 6:43,838,321...43,843,654 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:42,038,751...42,041,836
Ensembl chr26:42,038,528...42,041,760 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:122,635,383...122,674,298
Ensembl chr  X:122,635,439...122,674,355 		JBrowse link
G GAS1 growth arrest specific 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:97,590,381...97,593,209
Ensembl chr12:97,591,762...97,592,805 		JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:53,109,745...53,263,878
Ensembl chr 5:53,187,919...53,268,693 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr14:5,672,434...5,708,270
Ensembl chr14:5,673,163...5,708,372 		JBrowse link
G LOC103233229 cadherin-1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr 5:58,578,244...58,679,677
Ensembl chr 5:58,578,146...58,679,541 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216 		JBrowse link
G MAGEA3 MAGE family member A3 involved_in ISO (PMID:12097332) ParkinsonsUK-UCL PMID:12097332 NCBI chr  X:127,271,604...127,276,373 JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G NLRP7 NLR family pyrin domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,534,730...47,560,380
Ensembl chr 6:47,539,594...47,552,265 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170
G SNX12 sorting nexin 12 involved_in ISO (PMID:22709416) UniProt PMID:22709416 NCBI chr  X:60,849,241...60,866,846 JBrowse link
G TMEM98 transmembrane protein 98 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:26,468,148...26,481,681
Ensembl chr16:26,468,419...26,481,025 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr11:115,640,976...115,659,074
Ensembl chr11:115,640,555...115,658,687 		JBrowse link
negative regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:18056262) UniProt PMID:18056262
G CDK5 cyclin dependent kinase 5 involved_in ISO (PMID:24548080) ParkinsonsUK-UCL PMID:24548080 NCBI chr21:119,235,687...119,240,163 JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:26,320,132...26,343,009
Ensembl chr 5:26,320,061...26,337,402 		JBrowse link
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:52,834,497...52,838,785
Ensembl chr 2:52,832,181...52,838,865 		JBrowse link
G CSTA cystatin A involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:58,519,085...58,536,163
Ensembl chr22:58,519,085...58,536,339 		JBrowse link
G CSTB cystatin B involved_in ISO (PMID:3488317), (PMID:6203523) BHF-UCL PMID:3488317 PMID:6203523 NCBI chr 2:87,551,341...87,555,145 JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:45,927,625...45,951,636
Ensembl chr  X:45,928,092...45,952,929 		JBrowse link
G IDE insulin degrading enzyme ISO inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chr 9:85,722,728...85,843,247
Ensembl chr 9:85,721,886...85,843,117 		JBrowse link
G KNG1 kininogen 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:81,002,287...81,027,893 JBrowse link
G LOC103236354 prothrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,589,658...18,627,459
Ensembl chr 1:18,620,215...18,627,511
Ensembl chr 1:18,620,215...18,627,511 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,438,428...43,445,190
Ensembl chr 6:43,437,950...43,446,063 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,041,495...18,061,196
Ensembl chr 1:18,041,830...18,051,501 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:15161606 RGD:1625251 NCBI chr 4:64,321,296...64,406,188
Ensembl chr 4:64,321,078...64,406,519 		JBrowse link
G PLAT plasminogen activator, tissue type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:40,164,391...40,196,627
Ensembl chr 8:40,163,891...40,196,555 		JBrowse link
G RAB23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO (PMID:16364285) MGI PMID:16364285 NCBI chr17:14,383,064...14,418,144
Ensembl chr17:14,383,155...14,414,698 		JBrowse link
G SERPINA5 serpin family A member 5 ISO RGD PMID:16088033 RGD:1580291 NCBI chr24:72,369,082...72,388,439
Ensembl chr24:72,381,119...72,384,903 		JBrowse link
G SERPINB10 serpin family B member 10 ISO RGD PMID:11986314 RGD:634009 NCBI chr18:15,878,552...15,903,891
Ensembl chr18:15,878,191...15,894,609 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:12,047,520...12,060,662
Ensembl chr28:12,047,529...12,060,202 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:109,921,619...109,988,137
Ensembl chr10:109,921,598...109,987,513 		JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr23:50,587,698...50,667,219
Ensembl chr23:50,592,412...50,663,302 		JBrowse link
G SPINK9 serine peptidase inhibitor Kazal type 9 acts_upstream_of_or_within ISO (PMID:16930550) MGI PMID:16930550 NCBI chr23:50,972,629...50,976,856
Ensembl chr23:50,973,280...50,977,838 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:17532789 RGD:2290425 NCBI chr16:70,819,591...70,850,471
Ensembl chr16:70,819,139...70,850,471 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17532789 RGD:2290425 NCBI chr19:15,621,609...15,684,118
Ensembl chr19:15,622,431...15,680,449 		JBrowse link
G TM4SF20 transmembrane 4 L six family member 20 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:113,384,569...113,402,884
Ensembl chr10:113,383,898...113,402,277 		JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
G UBXN2A UBX domain protein 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:83,672,327...83,722,961
Ensembl chr14:83,673,282...83,703,633 		JBrowse link
G VTN vitronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:22,133,903...22,138,077
Ensembl chr16:22,133,138...22,136,815 		JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,695,446...8,702,556
Ensembl chr20:8,696,241...8,702,379 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:107,344,442...107,501,375
Ensembl chr10:107,352,530...107,499,788 		JBrowse link
G UFSP2 UFM1 specific peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:131,352,140...131,375,558
Ensembl chr 7:131,350,251...131,375,549 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:74,251,084...74,256,543
Ensembl chr 5:74,252,703...74,255,857 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr24:29,809,827...29,860,475
Ensembl chr24:29,809,806...29,856,608 		JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:6910481) UniProt PMID:6910481 NCBI chr25:21,787,237...21,909,462 JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:19240864 RGD:7411612 NCBI chr24:72,158,521...72,171,139
Ensembl chr24:72,156,784...72,163,500 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (PMID:20110462)
(PMID:22228629) 		RGD
MGI		 PMID:12771515 PMID:20110462 PMID:22228629 RGD:724699 NCBI chr23:50,365,686...50,373,300
Ensembl chr23:50,365,269...50,372,814 		JBrowse link
G SPINK2 serine peptidase inhibitor Kazal type 2 acts_upstream_of_or_within ISO (PMID:21705336) MGI PMID:21705336 NCBI chr 7:11,850,394...11,862,084 JBrowse link
G SPINK6 serine peptidase inhibitor Kazal type 6 acts_upstream_of_or_within ISO (PMID:24352040) MGI PMID:24352040 NCBI chr23:50,735,387...50,747,343 JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 acts_upstream_of_or_within ISO (PMID:20179351) MGI PMID:20179351 NCBI chr23:50,587,698...50,667,219
Ensembl chr23:50,592,412...50,663,302 		JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (PMID:20100865) MGI PMID:20100865 NCBI chr17:37,036,665...37,229,906
Ensembl chr17:37,036,066...37,155,596 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,159,770...46,168,831
Ensembl chr17:46,156,685...46,164,649 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:108,310,782...108,533,274
Ensembl chr21:108,322,096...108,533,226 		JBrowse link
G LOC103221857 E3 ubiquitin-protein ligase TRIM39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,142,185...42,159,256
Ensembl chr17:42,142,073...42,158,764 		JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within ISO (PMID:23792958) MGI PMID:23792958 NCBI chr14:4,275,182...4,289,041 JBrowse link
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,441,998...9,494,949
Ensembl chr26:9,451,112...9,494,931 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:26,547,305...26,551,327
Ensembl chr20:26,550,130...26,551,257 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:50,394,310...50,476,521
Ensembl chr24:50,405,590...50,472,132 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr25:2,862,354...2,888,735
Ensembl chr25:2,862,251...2,877,386 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861) UniProt PMID:30683861 NCBI chr16:45,370,569...45,407,297 JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr20:108,982,781...108,987,667
Ensembl chr20:108,981,723...108,987,734 		JBrowse link
G RPL23 ribosomal protein L23 involved_in ISO (PMID:15314173) CAFA PMID:15314173 NCBI chr16:67,341,370...67,345,141 JBrowse link
G RPL5 ribosomal protein L5 involved_in ISO (PMID:18560357) CAFA PMID:18560357 NCBI chr20:40,416,553...40,427,027
Ensembl chr20:40,413,897...40,427,060 		JBrowse link
G RPS7 ribosomal protein S7 involved_in ISO (PMID:17310983) CAFA PMID:17310983 NCBI chr14:104,069,825...104,075,669
Ensembl chr14:104,069,645...104,075,647 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,534,398...2,562,306
Ensembl chr 6:2,534,376...2,548,604 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:95,532,228...95,660,594
Ensembl chr 9:95,532,242...95,657,290 		JBrowse link
G SVIP small VCP interacting protein involved_in ISO PMID:17000876 ParkinsonsUK-UCL PMID:17000876 RGD:10047192 NCBI chr 1:42,185,115...42,193,121
Ensembl chr 1:42,185,121...42,195,006 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,167,743...61,269,000
Ensembl chr  X:61,167,589...61,268,839 		JBrowse link
G TAF1L TATA-box binding protein associated factor 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,620,400...47,626,369 JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:59,568,934...59,622,467
Ensembl chr18:59,568,844...59,621,476 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,885,401...6,899,983
Ensembl chr11:6,885,311...6,898,442 		JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:45,217,402...45,222,996
Ensembl chr11:45,219,027...45,222,017 		JBrowse link
positive regulation of anaphase-promoting complex-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDC20 cell division cycle 20 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:89,449,008...89,453,263
Ensembl chr20:89,444,165...89,453,044 		JBrowse link
G CDC20B cell division cycle 20B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:51,349,486...51,408,437
Ensembl chr 4:51,351,574...51,406,488 		JBrowse link
G FZR1 fizzy and cell division cycle 20 related 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:3,272,247...3,300,370
Ensembl chr 6:3,288,407...3,298,464 		JBrowse link
positive regulation of aspartic-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in ISO (PMID:28453791) UniProt PMID:28453791 NCBI chr16:62,037,344...62,045,765
Ensembl chr16:62,036,412...62,045,614 		JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKIRIN2 akirin 2 ISO MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr13:12,146,228...12,175,198 JBrowse link
G PRELID1 PRELI domain containing 1 involved_in ISO (PMID:18945965) UniProt PMID:18945965 NCBI chr23:79,313,442...79,316,788 JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in ISO (PMID:12660785) UniProt PMID:12660785 NCBI chr 6:30,655,162...30,656,587
Ensembl chr 6:30,655,243...30,656,584 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within ISO (PMID:19079247) MGI PMID:19079247 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in ISO (PMID:20666777) UniProt PMID:20666777 NCBI chr 9:59,516,012...59,538,628
Ensembl chr 9:59,516,073...59,542,242 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in ISO (PMID:17000876) ParkinsonsUK-UCL PMID:17000876 NCBI chr24:69,810,433...69,855,308 JBrowse link
G BAG6 BAG cochaperone 6 involved_in ISO (PMID:24424410) ParkinsonsUK-UCL PMID:24424410
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:128,128,739...128,152,617
Ensembl chr  X:128,128,271...128,151,823 		JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:42,877,812...42,889,576
Ensembl chr 5:42,877,781...42,890,298 		JBrowse link
G RNF185 ring finger protein 185 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,050,271...14,095,819
Ensembl chr19:14,076,113...14,093,410 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr16:33,483,167...33,496,608
Ensembl chr16:33,483,194...33,497,325 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr11:112,051,969...112,160,948
Ensembl chr11:112,052,097...112,160,793 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,534,398...2,562,306
Ensembl chr 6:2,534,376...2,548,604 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:599,907...602,549
Ensembl chr 5:599,819...605,567 		JBrowse link
G TMEM259 transmembrane protein 259 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:766,097...777,348
Ensembl chr 6:765,587...777,399 		JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr 8:88,726,783...88,818,111
Ensembl chr 8:88,726,837...88,792,049 		JBrowse link
G TMX1 thioredoxin related transmembrane protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:28,334,017...28,350,571
Ensembl chr24:28,333,357...28,352,457 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:94,462,867...94,512,313
Ensembl chr12:94,461,972...94,511,747 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:52,486,154...52,489,531
Ensembl chr  X:52,486,454...52,488,328 		JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:9,619,065...9,753,490
Ensembl chr15:9,624,300...9,753,466 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:42,404,028...42,437,988
Ensembl chr27:42,404,084...42,438,005 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (PMID:19911006) MGI PMID:19911006 NCBI chr19:11,670,605...11,677,168 JBrowse link
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr26:53,114,184...53,129,650
Ensembl chr26:53,114,924...53,126,900 		JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 involved_in ISO (PMID:9857183) BHF-UCL PMID:9857183 NCBI chr 8:37,017,827...37,131,462
Ensembl chr 8:37,017,545...37,131,615 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:104,015,577...104,019,364
Ensembl chr 9:104,016,580...104,017,932 		JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:25015123) ARUK-UCL PMID:25015123 NCBI chr 2:66,037,224...66,320,860
Ensembl chr 2:66,037,261...66,321,306 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:47,748,183...47,809,459
Ensembl chr17:47,765,699...47,804,378 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:63,785,493...63,791,071
Ensembl chr11:63,786,041...63,790,473 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:15,844,628...15,852,652
Ensembl chr14:15,844,672...15,850,729 		JBrowse link
G NRDC nardilysin convertase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:81,075,671...81,175,469
Ensembl chr20:81,075,869...81,175,447 		JBrowse link
G PACSIN3 protein kinase C and casein kinase substrate in neurons 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:18,125,207...18,135,866
Ensembl chr 1:18,130,727...18,135,454 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr29:11,592,929...11,638,955
Ensembl chr29:11,592,604...11,638,860 		JBrowse link
G SH3D19 SH3 domain containing 19 involved_in ISO (PMID:15280379) BHF-UCL PMID:15280379 NCBI chr 7:97,698,007...97,893,193
Ensembl chr 7:97,697,382...97,847,309 		JBrowse link
G SNX33 sorting nexin 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:7,776,989...7,787,873
Ensembl chr26:7,778,390...7,786,591 		JBrowse link
G SNX9 sorting nexin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:85,468,837...85,549,351
Ensembl chr13:85,468,479...85,549,988 		JBrowse link
G TNF tumor necrosis factor involved_in ISO (PMID:18373975) BHF-UCL PMID:18373975
G TNFRSF1B TNF receptor superfamily member 1B involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:119,590,621...119,633,562
Ensembl chr20:119,590,325...119,633,497 		JBrowse link
positive regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr20:7,884,220...7,927,738
Ensembl chr20:7,905,662...7,930,657 		JBrowse link
G MBP myelin basic protein involved_in ISO (PMID:22524708) CAFA PMID:22524708 NCBI chr18:2,844,154...2,996,640
Ensembl chr18:2,868,795...2,997,046 		JBrowse link
positive regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTXR1 ANTXR cell adhesion molecule 1 acts_upstream_of_or_within ISO (PMID:25572963) MGI PMID:25572963 NCBI chr14:37,849,911...38,116,339
Ensembl chr14:37,877,436...38,115,938 		JBrowse link
positive regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSH cathepsin H involved_in ISO (PMID:20435891) UniProt PMID:20435891 NCBI chr26:4,451,731...4,473,220
Ensembl chr26:4,451,774...4,472,855 		JBrowse link
G RCN3 reticulocalbin 3 involved_in ISO (PMID:28939891) UniProt PMID:28939891
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in ISO (PMID:9836589) ComplexPortal PMID:9836589 NCBI chr26:23,100,000...23,147,687
Ensembl chr26:23,099,992...23,145,457 		JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in ISO (PMID:12694198) UniProt PMID:12694198 NCBI chr22:6,501,082...6,510,878
Ensembl chr22:6,501,102...6,512,314 		JBrowse link
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:122,884,846...122,902,669
Ensembl chr20:122,884,727...122,903,372 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:79,414,074...79,438,896
Ensembl chr23:79,414,225...79,432,298 		JBrowse link
G HPN hepsin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,973,743...29,998,701
Ensembl chr 6:29,973,867...29,998,855 		JBrowse link
G MELTF melanotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:90,225,699...90,254,893
Ensembl chr15:90,225,780...90,255,263 		JBrowse link
G PLGRKT plasminogen receptor with a C-terminal lysine involved_in
acts_upstream_of_or_within 		IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr12:74,069,239...74,144,882
Ensembl chr12:74,069,306...74,144,454 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 ISO RGD PMID:11027681 RGD:67924 NCBI chr22:52,887,374...52,967,728
Ensembl chr22:52,924,819...52,967,830 		JBrowse link
G S100A10 S100 calcium binding protein A10 involved_in ISO (PMID:9836589) ComplexPortal PMID:9836589 NCBI chr20:11,690,580...11,701,561 JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,420,196...14,432,910
Ensembl chr17:14,420,947...14,433,354 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:17,802,030...18,017,648
Ensembl chr12:17,801,831...17,830,890 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:33,846,591...33,879,770
Ensembl chr 2:33,860,439...33,880,101 		JBrowse link
G ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:42,124,181...42,137,577
Ensembl chr23:42,123,875...42,137,196 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 involved_in ISO (PMID:24709664) UniProt PMID:24709664 NCBI chr  X:122,635,383...122,674,298
Ensembl chr  X:122,635,439...122,674,355 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:57,833,459...57,841,052
Ensembl chr 2:57,833,629...57,834,000 		JBrowse link
G NEURL3 neuralized E3 ubiquitin protein ligase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:846,637...854,279
Ensembl chr14:847,229...853,926 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,382,125...26,385,605
Ensembl chr 5:26,382,132...26,385,348 		JBrowse link
G OAZ1 ornithine decarboxylase antizyme 1 ISO RGD PMID:12359729 RGD:7245486 NCBI chr 6:2,061,774...2,065,595
Ensembl chr 6:2,061,811...2,065,265 		JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in ISO (PMID:21669198) BHF-UCL PMID:21669198 NCBI chr16:68,208,121...68,222,684 JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:68,215,177...68,222,651 JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:23858059) ParkinsonsUK-UCL PMID:23858059 NCBI chr13:88,856,056...90,329,379 JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 Ensembl chr13:89,318,323...90,034,758 JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr21:72,323,691...72,341,647
Ensembl chr21:72,323,803...72,341,488 		JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr 5:27,449,633...27,462,591
Ensembl chr 5:27,449,908...27,463,754 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:83,515,494...83,571,644
Ensembl chr11:83,521,169...83,571,695 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:29518356) ARUK-UCL PMID:29518356 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in
acts_upstream_of_or_within 		IEA Ensembl GO_REF:0000107 NCBI chr24:82,704,087...82,730,711
Ensembl chr24:82,704,068...82,727,698 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:23152632) MGI PMID:23152632 NCBI chr22:47,187,305...47,571,309
Ensembl chr22:47,325,614...47,571,070 		JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:7,730,060...7,753,167
Ensembl chr 2:7,734,128...7,752,395 		JBrowse link
G AXIN1 axin 1 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575 		JBrowse link
G AXIN2 axin 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:55,874,043...55,906,739
Ensembl chr16:55,874,072...55,907,281 		JBrowse link
G BAG2 BAG cochaperone 2 NOT|involved_in ISO (PMID:19228967) ARUK-UCL PMID:19228967 NCBI chr17:14,420,196...14,432,910
Ensembl chr17:14,420,947...14,433,354 		JBrowse link
G BBS7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:69,100,287...69,153,009
Ensembl chr 7:69,101,662...69,152,768 		JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:74,260,516...74,361,268
Ensembl chr 5:74,263,375...74,289,875 		JBrowse link
G CHFR checkpoint with forkhead and ring finger domains acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:128,175,768...128,207,710
Ensembl chr11:128,175,515...128,207,443 		JBrowse link
G CLU clusterin involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:25,704,441...25,721,789
Ensembl chr 8:25,703,257...25,721,789 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:53,057,479...53,316,662
Ensembl chr25:53,057,784...53,314,398 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:52,111,500...52,169,043
Ensembl chr23:52,114,053...52,168,998 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISO (PMID:19414593) UniProt PMID:19414593 NCBI chr16:74,157,875...74,192,142
Ensembl chr16:74,160,648...74,192,108 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:38,171,320...38,224,275
Ensembl chr 4:38,173,026...38,224,231 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:15,815,956...15,826,873
Ensembl chr 6:15,816,030...15,826,232 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:33,846,591...33,879,770
Ensembl chr 2:33,860,439...33,880,101 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr29:7,078,777...7,103,174
Ensembl chr29:7,078,578...7,096,486 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:105,185,987...105,193,749
Ensembl chr10:105,186,608...105,194,574 		JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:130,105,032...130,118,978
Ensembl chr20:130,104,639...130,117,139 		JBrowse link
G FBXO22 F-box protein 22 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr26:7,357,813...7,387,344
Ensembl chr26:7,356,064...7,387,274 		JBrowse link
G FBXW8 F-box and WD repeat domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:112,226,545...112,337,164
Ensembl chr11:112,226,594...112,341,225 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:6,614,478...6,616,516
Ensembl chr16:6,614,688...6,616,443 		JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:23707074) ParkinsonsUK-UCL PMID:23707074 NCBI chr20:8,598,110...8,631,517
Ensembl chr20:8,598,628...8,630,990 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within ISO (PMID:17189825) MGI PMID:17189825 NCBI chr17:19,012,994...19,060,617
Ensembl chr17:19,013,026...19,060,659 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:36,434,966...36,447,676
Ensembl chr 6:36,435,578...36,447,633 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta involved_in
acts_upstream_of_or_within 		IEA
ISO 		(PMID:22660580) Ensembl
TreeGrafter
MGI		 PMID:22660580 GO_REF:0000107 GO_REF:0000118 NCBI chr22:60,732,449...61,002,735
Ensembl chr22:60,733,465...60,997,239 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,214,820...30,218,100
Ensembl chr 6:30,215,563...30,217,996 		JBrowse link
G HSPBP1 HSPA (Hsp70) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:47,861,634...47,884,293
Ensembl chr 6:47,861,593...47,884,218 		JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:73,235,585...73,283,665
Ensembl chr12:73,237,406...73,252,436 		JBrowse link
G KLHL40 kelch like family member 40 involved_in ISO (PMID:25940086) UniProt PMID:25940086 NCBI chr22:4,141,759...4,149,158
Ensembl chr22:4,142,192...4,148,710 		JBrowse link
G LOC103221743 heat shock 70 kDa protein 1A involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr17:40,191,695...40,194,459
Ensembl chr17:40,203,936...40,205,858 		JBrowse link
G LOC103221745 heat shock 70 kDa protein 1A involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr17:40,203,647...40,206,028
Ensembl chr17:40,203,936...40,205,858 		JBrowse link
G LOC103223312 casein kinase I involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:20,992,927...21,025,866
Ensembl chr19:20,998,009...21,022,576 		JBrowse link
G LOC119623630 lysosomal acid glucosylceramidase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107
G LOC119624365 small ubiquitin-related modifier 2 involved_in IEA Ensembl GO_REF:0000107
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:36,490,775...36,634,215
Ensembl chr11:36,492,011...36,634,216 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO (PMID:29153991) UniProt PMID:29153991 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:81,965,330...82,026,414
Ensembl chr23:81,963,899...82,013,659 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:64,434,203...64,465,490
Ensembl chr11:64,434,261...64,469,890 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:857,938...884,840
Ensembl chr 4:858,809...884,758 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:41,058,199...41,070,220
Ensembl chr 6:41,057,906...41,071,202 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:119,525,757...119,559,412
Ensembl chr21:119,525,932...119,560,886 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:79,877,288...79,879,862
Ensembl chr12:79,877,416...79,878,279 		JBrowse link
G PAQR3 progestin and adipoQ receptor family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:27,358,443...27,385,612
Ensembl chr 7:27,367,059...27,385,568 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:15,294,296...15,432,731
Ensembl chr26:15,297,934...15,432,659 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,388,957...21,408,574
Ensembl chr 5:21,396,204...21,410,718 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:18723513 RGD:7241135 NCBI chr 4:54,629,868...54,636,134
Ensembl chr 4:54,629,194...54,636,032 		JBrowse link
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:87,989,573...87,995,396
Ensembl chr20:87,989,574...87,994,478 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:38,696,771...38,819,324
Ensembl chr11:38,694,602...38,718,519 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:23858059) ParkinsonsUK-UCL PMID:23858059 NCBI chr13:88,856,056...90,329,379 JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr24:50,394,310...50,476,521
Ensembl chr24:50,405,590...50,472,132 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (PMID:20208556) BHF-UCL PMID:20208556 NCBI chr25:2,862,354...2,888,735
Ensembl chr25:2,862,251...2,877,386 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:95,931,710...95,939,145
Ensembl chr  X:95,931,466...95,939,218 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:82,800,211...82,805,769
Ensembl chr23:82,798,085...82,805,936 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:11,625,464...11,633,922
Ensembl chr 6:11,625,458...11,637,419 		JBrowse link
G RBX1 ring-box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:23,500,361...23,521,676
Ensembl chr19:23,500,356...23,522,723 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,989,028...24,025,151
Ensembl chr 7:23,989,745...24,025,437 		JBrowse link
G RFPL1 ret finger protein like 1 involved_in ISO (PMID:20725088) UniProt PMID:20725088 NCBI chr19:12,312,974...12,316,146 JBrowse link
G RNF180 ring finger protein 180 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 4:60,340,926...60,555,932
Ensembl chr 4:60,340,804...60,557,227 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:48,512,549...48,655,652
Ensembl chr23:48,512,548...48,658,365 		JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:63,463,059...63,497,893
Ensembl chr 9:63,462,389...63,497,867 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,493,106...33,518,793
Ensembl chr 6:33,493,079...33,518,647 		JBrowse link
G SIRT6 sirtuin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:3,924,230...3,932,583
Ensembl chr 6:3,924,230...3,932,590 		JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr24:32,198,438...32,227,240
Ensembl chr24:32,220,800...32,222,122 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr14:60,330,192...60,335,477
Ensembl chr14:60,431,401...60,433,011
Ensembl chr14:60,431,401...60,433,011 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:599,907...602,549
Ensembl chr 5:599,819...605,567 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr10:87,917,324...87,957,152 JBrowse link
G SUMO2 small ubiquitin like modifier 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:46,479,399...46,495,591
Ensembl chr16:46,479,406...46,496,114 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,167,743...61,269,000
Ensembl chr  X:61,167,589...61,268,839 		JBrowse link
G TAF1L TATA-box binding protein associated factor 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,620,400...47,626,369 JBrowse link
G TF transferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,586,311...56,618,304
Ensembl chr15:56,586,104...56,618,149 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:120,013,757...120,021,823
Ensembl chr 8:120,014,339...120,019,887 		JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in ISO (PMID:20410507) BHF-UCL PMID:20410507 NCBI chr14:94,887,152...94,913,219 JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 Ensembl chr14:94,903,597...94,912,033 JBrowse link
G TRIB3 tribbles pseudokinase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:35,512,911...35,530,856
Ensembl chr 2:35,512,861...35,530,966 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 8:44,167,214...44,218,074 JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:6,885,401...6,899,983
Ensembl chr11:6,885,311...6,898,442 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:45,545,139...45,560,702
Ensembl chr12:45,545,507...45,563,380 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:9,371,038...9,413,127
Ensembl chr12:9,371,701...9,413,134 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr28:20,434,434...20,441,641
Ensembl chr28:20,434,495...20,442,322 		JBrowse link
G ZYG11B zyg-11 family member B, cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:80,120,970...80,214,538
Ensembl chr20:80,122,056...80,214,422 		JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPTL8 angiopoietin like 8 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 6:10,169,733...10,172,433
Ensembl chr 6:10,170,052...10,173,005 		JBrowse link
G ASTL astacin like metalloendopeptidase involved_in ISO (PMID:22472438) UniProt PMID:22472438 NCBI chr14:568,071...577,182 JBrowse link
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,420,196...14,432,910
Ensembl chr17:14,420,947...14,433,354 		JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,054,281...20,363,024
Ensembl chr18:20,271,874...20,309,784 		JBrowse link
G CNTN2 contactin 2 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr25:24,262,092...24,296,740
Ensembl chr25:24,261,651...24,296,850 		JBrowse link
G CTNND1 catenin delta 1 acts_upstream_of_or_within ISO (PMID:17344476) MGI PMID:17344476 NCBI chr 1:15,408,581...15,466,457
Ensembl chr 1:15,411,454...15,466,456 		JBrowse link
G FUZ fuzzy planar cell polarity protein acts_upstream_of_or_within ISO (PMID:19877275) MGI PMID:19877275 NCBI chr 6:42,968,715...42,975,374
Ensembl chr 6:42,969,000...42,975,368 		JBrowse link
G MBL2 mannose binding lectin 2 ISO Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr 9:78,389,534...78,394,753
Ensembl chr 9:78,389,947...78,396,079 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:14668206 RGD:1582606 NCBI chr29:23,201,425...23,212,408
Ensembl chr29:23,201,112...23,212,679 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:857,938...884,840
Ensembl chr 4:858,809...884,758 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:75,229,262...75,273,336
Ensembl chr14:75,242,274...75,273,312 		JBrowse link
G RHBDD1 rhomboid domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:112,882,789...113,018,889
Ensembl chr10:112,882,789...113,020,732 		JBrowse link
G SPON1 spondin 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:50,616,983...50,907,120
Ensembl chr 1:50,616,007...50,906,622 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:26,344,480...26,367,448
Ensembl chr 2:26,343,450...26,367,776 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A ISO RGD PMID:9756630 RGD:13463485 NCBI chr25:27,436,066...27,450,512 JBrowse link
G TNP1 transition protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:102,703,116...102,703,747
Ensembl chr10:102,703,325...102,703,691 		JBrowse link
G TNP2 transition protein 2 involved_in ISO (PMID:28366643) UniProt PMID:28366643 NCBI chr 5:10,744,762...10,746,244
Ensembl chr 5:10,744,915...10,746,159 		JBrowse link
positive regulation of protein processing in phagocytic vesicle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:18,253,079...18,317,285
Ensembl chr12:18,253,324...18,285,938 		JBrowse link
G MYH9 myosin heavy chain 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,985,709...19,093,304
Ensembl chr19:18,986,598...19,052,671 		JBrowse link
positive regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASPH aspartate beta-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:57,378,019...57,599,812
Ensembl chr 8:57,375,894...57,565,259 		JBrowse link
G AURKAIP1 aurora kinase A interacting protein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:130,074,660...130,076,355
Ensembl chr20:130,075,295...130,076,765 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,949,717...9,964,433
Ensembl chr 1:9,949,762...9,964,432 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:38,492,776...38,502,534
Ensembl chr17:38,492,858...38,501,281 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678 		JBrowse link
G CAPN3 calpain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:40,568,320...40,657,443
Ensembl chr26:40,568,885...40,625,597 		JBrowse link
G CASP8 caspase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:86,888,654...86,944,159
Ensembl chr10:86,916,527...86,943,829 		JBrowse link
G CD46 CD46 molecule ISO RGD PMID:15215199 RGD:2293559 NCBI chr25:21,650,825...21,693,898
Ensembl chr25:21,655,969...21,693,878 		JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:24093776 RGD:11570550 NCBI chr 1:8,408,560...8,410,564 JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in ISO (PMID:15010453) UniProt PMID:15010453 NCBI chr26:15,259,186...15,278,249 JBrowse link
G CLN6 CLN6 transmembrane ER protein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:15,266,732...15,278,418 JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:59,661,045...59,794,717
Ensembl chr23:59,661,089...59,794,826 		JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:16973938 RGD:2289912 NCBI chr19:23,634,132...23,726,095
Ensembl chr19:23,634,571...23,724,979 		JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr 1:4,358,314...4,361,863 JBrowse link
G FBXW11 F-box and WD repeat domain containing 11 involved_in ISO (PMID:16885022) UniProt PMID:16885022 NCBI chr23:74,015,964...74,154,285
Ensembl chr23:74,015,964...74,154,062 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:79,095,031...79,106,018
Ensembl chr23:79,097,429...79,105,456 		JBrowse link
G HDAC2 histone deacetylase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:59,873,248...59,904,542
Ensembl chr13:59,873,767...59,905,742 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 ISO RGD PMID:9987077 RGD:10059370 NCBI chr 1:114,447,348...114,452,693
Ensembl chr 1:114,446,544...114,451,562 		JBrowse link
G IST1 IST1 factor associated with ESCRT-III involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:55,030,916...55,063,824
Ensembl chr 5:55,050,795...55,064,549 		JBrowse link
G OGA O-GlcNAcase ISO Degradation of calmodulin-dependent protein kinase II and alpha fodrin (RGD: 621714). RGD PMID:17573462 RGD:2305953 NCBI chr 9:94,812,126...94,847,118 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:61,351,047...61,393,541
Ensembl chr  X:61,351,054...61,394,305 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,305,552...35,322,112
Ensembl chr13:35,305,678...35,322,099 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:21,388,957...21,408,574
Ensembl chr 5:21,396,204...21,410,718 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:599,907...602,549
Ensembl chr 5:599,819...605,567 		JBrowse link
G TBC1D10A TBC1 domain family member 10A involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:13,172,847...13,207,979
Ensembl chr19:13,172,845...13,207,904 		JBrowse link
G TRIM32 tripartite motif containing 32 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,893,689...22,906,913
Ensembl chr12:22,894,886...22,896,847 		JBrowse link
positive regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5IF1 ATP synthase inhibitory factor subunit 1 involved_in ISO (PMID:24005319) ParkinsonsUK-UCL PMID:24005319 NCBI chr20:104,567,306...104,569,346 JBrowse link
G CTSC cathepsin C involved_in ISO PMID:18307834 ParkinsonsUK-UCL PMID:18307834 RGD:8661625 NCBI chr 1:79,426,556...79,468,464
Ensembl chr 1:79,426,549...79,468,340 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:33,846,591...33,879,770
Ensembl chr 2:33,860,439...33,880,101 		JBrowse link
G GBA1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:21700325) ARUK-UCL PMID:21700325 NCBI chr20:8,598,110...8,631,517
Ensembl chr20:8,598,628...8,630,990 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:102,080,500...102,106,649
Ensembl chr20:102,080,508...102,106,729 		JBrowse link
G LOC119623630 lysosomal acid glucosylceramidase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107
G RGN regucalcin ISO RGD PMID:1513338 RGD:9590188 NCBI chr  X:44,282,825...44,299,027
Ensembl chr  X:44,285,601...44,299,258 		JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:77,357,239...77,387,385
Ensembl chr13:77,357,141...77,387,367 		JBrowse link
positive regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:2972794) UniProt PMID:2972794 NCBI chr25:21,787,237...21,909,462 JBrowse link
G LOC103214213 semenogelin 1 involved_in ISO (PMID:15563730) UniProt PMID:15563730 NCBI chr 2:18,600,260...18,626,326 JBrowse link
G SEMG2 semenogelin 2 involved_in ISO (PMID:15563730) UniProt PMID:15563730
positive regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGBL4 AGBL carboxypeptidase 4 acts_upstream_of_or_within ISO (PMID:29593216) MGI PMID:29593216 NCBI chr20:82,893,087...84,293,578 JBrowse link
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr12:96,342,193...96,534,981
Ensembl chr12:96,342,759...96,534,800 		JBrowse link
G ATXN3 ataxin 3 involved_in ISO (PMID:17000876) ParkinsonsUK-UCL PMID:17000876 NCBI chr24:69,810,433...69,855,308 JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in 		IEA
ISO 		PMID:10228155 Ensembl
BHF-UCL		 PMID:10228155 GO_REF:0000107 RGD:8553327 NCBI chr 5:233,520...295,134
Ensembl chr 5:234,060...290,575 		JBrowse link
G BCAP31 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:128,128,739...128,152,617
Ensembl chr  X:128,128,271...128,151,823 		JBrowse link
G CCDC22 CCC complex scaffolding subunit CCDC22 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr  X:46,330,215...46,349,978
Ensembl chr  X:46,335,095...46,353,583 		JBrowse link
G CDK5RAP3 CDK5 regulatory subunit associated protein 3 NOT|involved_in ISO (PMID:16173922) UniProt PMID:16173922 NCBI chr16:68,367,591...68,382,000
Ensembl chr16:68,370,483...68,382,022 		JBrowse link
G CLU clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,704,441...25,721,789
Ensembl chr 8:25,703,257...25,721,789 		JBrowse link
G DISC1 DISC1 scaffold protein acts_upstream_of_or_within ISO (PMID:20880836) MGI PMID:20880836 NCBI chr25:68,886,451...69,274,774
Ensembl chr25:68,946,430...69,263,198 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:57,810,110...57,911,361
Ensembl chr 7:57,811,728...57,911,516 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr26:7,357,813...7,387,344
Ensembl chr26:7,356,064...7,387,274 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:98,894,261...99,105,955
Ensembl chr 7:98,892,504...99,106,084 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:42,877,812...42,889,576
Ensembl chr 5:42,877,781...42,890,298 		JBrowse link
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:43,428,693...43,554,996
Ensembl chr13:43,428,694...43,554,972 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:102,080,500...102,106,649
Ensembl chr20:102,080,508...102,106,729 		JBrowse link
G MTOR mechanistic target of rapamycin kinase acts_upstream_of IEA Ensembl GO_REF:0000107 NCBI chr20:120,522,667...120,678,988
Ensembl chr20:120,525,737...120,679,020 		JBrowse link
G PTEN phosphatase and tensin homolog involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:81,308,058...81,412,386
Ensembl chr 9:81,309,099...81,409,146 		JBrowse link
G PTK2 protein tyrosine kinase 2 involved_in ISO (PMID:18206965) UniProt PMID:18206965 NCBI chr 8:134,897,511...135,246,300 JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782 		JBrowse link
G PYHIN1 pyrin and HIN domain family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:4,967,123...5,006,172
Ensembl chr20:4,967,224...5,006,035 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:119,041,885...119,055,119
Ensembl chr 8:119,042,223...119,054,486 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,534,398...2,562,306
Ensembl chr 6:2,534,376...2,548,604 		JBrowse link
G SMURF1 SMAD specific E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:14,019,733...14,141,588
Ensembl chr28:14,019,968...14,141,795 		JBrowse link
G SUMO3 small ubiquitin like modifier 3 acts_upstream_of_or_within ISO (PMID:18644859) MGI PMID:18644859 NCBI chr 2:88,516,906...88,529,098 JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 involved_in ISO (PMID:18762808) BHF-UCL PMID:18762808 NCBI chr 5:28,172,246...28,178,265 JBrowse link
G TRAF7 TNF receptor associated factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:2,051,247...2,072,763
Ensembl chr 5:2,059,349...2,071,297 		JBrowse link
G TRIM67 tripartite motif containing 67 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr25:68,434,458...68,488,471
Ensembl chr25:68,434,543...68,487,727 		JBrowse link
G VCP valosin containing protein ISO RGD PMID:16103111 RGD:1599730 NCBI chr12:45,545,139...45,560,702
Ensembl chr12:45,545,507...45,563,380 		JBrowse link
positive regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TANK TRAF family member associated NFKB activator involved_in ISO (PMID:25861989) UniProt PMID:25861989 NCBI chr10:46,527,795...46,632,133
Ensembl chr10:46,556,614...46,632,186 		JBrowse link
regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2ML1 alpha-2-macroglobulin like 1 involved_in ISO (PMID:16298998) UniProt PMID:16298998 NCBI chr11:8,638,320...8,695,696
Ensembl chr11:8,638,826...8,693,355 		JBrowse link
regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:42,877,812...42,889,576
Ensembl chr 5:42,877,781...42,890,298 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:10,510,554...10,523,576
Ensembl chr22:10,510,423...10,523,487 		JBrowse link
regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TSPAN15 tetraspanin 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:61,813,896...61,869,057
Ensembl chr 9:61,813,686...61,868,987 		JBrowse link
G TSPAN17 tetraspanin 17 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:78,654,954...78,667,299
Ensembl chr23:78,655,055...78,667,462 		JBrowse link
G TSPAN5 tetraspanin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:46,610,841...46,788,761
Ensembl chr 7:46,609,602...46,788,704 		JBrowse link
regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RHBDF2 rhomboid 5 homolog 2 acts_upstream_of_or_within ISO (PMID:29897333) MGI PMID:29897333 NCBI chr16:45,176,152...45,205,464
Ensembl chr16:45,194,852...45,204,761 		JBrowse link
regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SVBP small vasohibin binding protein involved_in ISO (PMID:31171830), (PMID:31235910), (PMID:31235911), (PMID:31270470) UniProt PMID:31171830 PMID:31235910 PMID:31235911 PMID:31270470 NCBI chr20:90,115,509...90,128,169
Ensembl chr20:90,116,353...90,127,807 		JBrowse link
regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAV1 caveolin 1 acts_upstream_of_or_within ISO (PMID:17349656) MGI PMID:17349656 NCBI chr21:85,222,724...85,258,562
Ensembl chr21:85,222,879...85,258,627 		JBrowse link
regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G BTRC beta-transducin repeat containing E3 ubiquitin protein ligase acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 9:94,333,046...94,581,327
Ensembl chr 9:94,376,055...94,574,678 		JBrowse link
G DLGAP1 DLG associated protein 1 involved_in ISO PMID:15496675 BHF-UCL PMID:15496675 RGD:8553458 NCBI chr18:62,731,283...63,680,849
Ensembl chr18:62,730,753...63,091,140 		JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in ISO (PMID:19423554) UniProt PMID:19423554 NCBI chr26:27,946,092...28,024,495 JBrowse link
G DNAAF4 dynein axonemal assembly factor 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:27,960,224...28,013,105 JBrowse link
G EPM2A EPM2A glucan phosphatase, laforin acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr13:26,152,974...26,266,676
Ensembl chr13:26,153,319...26,264,568 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in ISO (PMID:12751788) BHF-UCL PMID:12751788 NCBI chr22:10,754,976...10,756,617 JBrowse link
G GPX1 glutathione peroxidase 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr22:10,754,970...10,757,057 JBrowse link
G LOC103245280 proteasome activator complex subunit 2-like involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr26:7,002,138...7,002,964 JBrowse link
G NFE2L1 NFE2 like bZIP transcription factor 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr16:68,449,601...68,463,030
Ensembl chr16:68,449,898...68,461,190 		JBrowse link
G NUDT15 nudix hydrolase 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:25,966,148...25,974,143
Ensembl chr 3:25,966,876...25,973,647 		JBrowse link
G PITHD1 PITH domain containing 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:108,896,650...108,906,409
Ensembl chr20:108,897,503...108,906,289 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:1,985,165...2,031,518
Ensembl chr 5:1,983,632...2,015,551 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in ISO (PMID:17565987) UniProt PMID:17565987 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:12,727,643...12,758,915 JBrowse link
G PSMD14 proteasome 26S subunit, non-ATPase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:46,703,876...46,814,938
Ensembl chr10:46,704,098...46,815,132 		JBrowse link
G PSME1 proteasome activator subunit 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:1,122,086...1,124,907
Ensembl chr24:1,122,631...1,125,416 		JBrowse link
G PSME2 proteasome activator subunit 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr24:1,129,389...1,133,289
Ensembl chr24:1,129,419...1,132,596 		JBrowse link
G PSME3 proteasome activator subunit 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:63,449,954...63,460,490
Ensembl chr16:63,452,105...63,460,199 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA UniProt GO_REF:0000117 NCBI chr 6:11,625,464...11,633,922
Ensembl chr 6:11,625,458...11,637,419 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein involved_in IEA UniProt GO_REF:0000117 NCBI chr12:32,203,501...32,250,555
Ensembl chr12:32,204,893...32,250,570 		JBrowse link
G RHBDF1 rhomboid 5 homolog 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:14,935...34,991
Ensembl chr 5:13,071...21,883 		JBrowse link
G TMF1 TATA element modulatory factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,048,269...30,078,600
Ensembl chr22:30,045,685...30,078,414 		JBrowse link
G UBB ubiquitin B acts_upstream_of_or_within ISO (PMID:17571083) MGI PMID:17571083 NCBI chr16:15,279,271...15,289,111 JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA UniProt GO_REF:0000117 NCBI chr12:94,462,867...94,512,313
Ensembl chr12:94,461,972...94,511,747 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA UniProt GO_REF:0000117 NCBI chr  X:52,486,154...52,489,531
Ensembl chr  X:52,486,454...52,488,328 		JBrowse link
G UBQLN3 ubiquilin 3 involved_in IEA UniProt GO_REF:0000117 NCBI chr 1:61,204,974...61,207,613
Ensembl chr 1:61,205,355...61,207,322 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA UniProt GO_REF:0000117 Ensembl chr20:7,811,220...7,821,203 JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:36,362,340...36,415,550
Ensembl chr25:36,364,027...36,414,762 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:59,568,934...59,622,467
Ensembl chr18:59,568,844...59,621,476 		JBrowse link
regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A involved_in ISO (PMID:36822331) DisProt PMID:36822331 NCBI chr 5:10,420,866...10,658,370
Ensembl chr 5:10,420,931...10,658,507 		JBrowse link
G COMMD1 copper metabolism domain containing 1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr14:44,839,460...45,068,764
Ensembl chr14:44,839,542...45,068,586 		JBrowse link
G DDA1 DET1 and DDB1 associated 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 6:15,815,956...15,826,873
Ensembl chr 6:15,816,030...15,826,232 		JBrowse link
G DESI1 desumoylating isopeptidase 1 involved_in ISO (PMID:29666234) UniProt PMID:29666234 NCBI chr19:24,135,266...24,160,391
Ensembl chr19:24,134,802...24,160,401 		JBrowse link
G FOXF2 forkhead box F2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:70,744,989...70,750,860
Ensembl chr17:70,745,011...70,750,652 		JBrowse link
G GLMN glomulin, FKBP associated protein acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:40,950,948...41,007,120
Ensembl chr20:40,951,342...41,008,791 		JBrowse link
G GNA12 G protein subunit alpha 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr28:18,778,768...18,890,420
Ensembl chr28:18,778,847...18,888,922 		JBrowse link
G LOC103231895 serine/threonine-protein kinase A-Raf involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:44,738,406...44,748,996
Ensembl chr  X:44,740,181...44,748,550 		JBrowse link
G LOC119623210 serine/threonine-protein kinase A-Raf involved_in IEA Ensembl GO_REF:0000107
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:11,625,464...11,633,922
Ensembl chr 6:11,625,458...11,637,419 		JBrowse link
G RAD23B RAD23 homolog B, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:32,203,501...32,250,555
Ensembl chr12:32,204,893...32,250,570 		JBrowse link
G UBE2K ubiquitin conjugating enzyme E2 K acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr27:10,535,091...10,618,659
Ensembl chr27:10,539,402...10,618,573 		JBrowse link
G UBQLN4 ubiquilin 4 involved_in ISO (PMID:27113755)
(PMID:15280365) 		UniProt PMID:15280365 PMID:27113755 NCBI chr20:7,811,275...7,829,782 JBrowse link
G UBQLN4 ubiquilin 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr20:7,811,220...7,821,203 JBrowse link
G UFL1 UFM1 specific ligase 1 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr13:77,357,239...77,387,385
Ensembl chr13:77,357,141...77,387,367 		JBrowse link
G WNT10B Wnt family member 10B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:45,205,728...45,229,050
Ensembl chr11:45,205,566...45,210,893 		JBrowse link
G XPO1 exportin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:45,428,279...45,487,965
Ensembl chr14:45,432,619...45,488,723 		JBrowse link
G ZNF416 zinc finger protein 416 involved_in ISO PMID:33249983
(PMID:33249983) 		UniProt PMID:33249983 RGD:329955556 NCBI chr 6:49,943,136...49,950,935 JBrowse link
regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:26,320,132...26,343,009
Ensembl chr 5:26,320,061...26,337,402 		JBrowse link
G CWH43 cell wall biogenesis 43 C-terminal homolog acts_upstream_of_or_within ISO (PMID:34380733) MGI PMID:34380733 NCBI chr27:1,199,363...1,281,422
Ensembl chr27:1,199,370...1,281,308 		JBrowse link
G IFT52 intraflagellar transport 52 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 2:20,154,246...20,211,754
Ensembl chr 2:20,152,036...20,211,682 		JBrowse link
G IFT88 intraflagellar transport 88 acts_upstream_of_or_within ISO (PMID:16254602)
(PMID:15930098) 		MGI PMID:15930098 PMID:16254602 NCBI chr 3:435,649...546,661
Ensembl chr 3:436,207...546,583 		JBrowse link
G INPP5B inositol polyphosphate-5-phosphatase B acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:94,919,605...95,001,487
Ensembl chr20:94,920,402...95,001,248 		JBrowse link
G LDLRAD3 low density lipoprotein receptor class A domain containing 3 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 1:29,017,428...29,317,531
Ensembl chr 1:29,017,115...29,317,476 		JBrowse link
G NOTCH4 notch receptor 4 acts_upstream_of_or_within ISO (PMID:24667410) MGI PMID:24667410 NCBI chr17:39,806,864...39,837,101
Ensembl chr17:39,808,035...39,837,365 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within ISO (PMID:22007132) MGI PMID:22007132 NCBI chr 6:12,743,752...12,759,155 JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 Ensembl chr 6:12,727,643...12,758,915 JBrowse link
G PRKACB protein kinase cAMP-activated catalytic subunit beta acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr20:49,109,774...49,273,200
Ensembl chr20:49,108,425...49,178,806 		JBrowse link
G PRSS37 serine protease 37 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:110,583,991...110,588,985
Ensembl chr21:110,584,109...110,588,046 		JBrowse link
G RFX4 regulatory factor X4 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:101,790,944...101,972,314
Ensembl chr11:101,791,212...101,972,362 		JBrowse link
G RNF139 ring finger protein 139 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:119,041,885...119,055,119
Ensembl chr 8:119,042,223...119,054,486 		JBrowse link
G RPS6KA2 ribosomal protein S6 kinase A2 acts_upstream_of_or_within ISO (PMID:16585392) MGI PMID:16585392 NCBI chr13:94,141,648...94,605,750
Ensembl chr13:94,140,111...94,357,688 		JBrowse link
regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G L3MBTL3 L3MBTL histone methyl-lysine binding protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:43,428,693...43,554,996
Ensembl chr13:43,428,694...43,554,972 		JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:21,901,153...21,966,227
Ensembl chr13:21,919,280...21,967,117 		JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr21:119,525,757...119,559,412
Ensembl chr21:119,525,932...119,560,886 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:25,437,680...25,571,594
Ensembl chr 8:25,437,564...25,571,782 		JBrowse link
G TMEM168 transmembrane protein 168 acts_upstream_of_or_within ISO (PMID:32175648) MGI PMID:32175648 NCBI chr21:81,567,647...81,594,451 JBrowse link
G UBE3A ubiquitin protein ligase E3A involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:56,638,936...56,738,555
Ensembl chr26:56,666,162...56,736,737 		JBrowse link
zymogen inhibition term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FURIN furin, paired basic amino acid cleaving enzyme involved_in ISO (PMID:11799113), (PMID:9130696) UniProt PMID:9130696 PMID:11799113 NCBI chr29:8,980,367...8,992,257
Ensembl chr29:8,979,720...8,988,235 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19826
    cellular process 19340
      metabolic process 13108
        macromolecule metabolic process 11125
          protein metabolic process 4497
            proteolysis 1409
              regulation of proteolysis 415
                negative regulation of proteolysis + 151
                positive regulation of proteolysis + 220
                regulation of membrane protein ectodomain proteolysis + 27
                regulation of peptidase activity + 42
                regulation of protein processing + 64
                regulation of proteolysis involved in protein catabolic process + 249
Path 2
Term Annotations click to browse term
  biological_process 19826
    biological regulation 12155
      regulation of biological process 11760
        regulation of cellular process 11395
          regulation of metabolic process 6642
            regulation of primary metabolic process 5263
              regulation of protein metabolic process 1831
                regulation of proteolysis 415
                  negative regulation of proteolysis + 151
                  positive regulation of proteolysis + 220
                  regulation of membrane protein ectodomain proteolysis + 27
                  regulation of peptidase activity + 42
                  regulation of protein processing + 64
                  regulation of proteolysis involved in protein catabolic process + 249
paths to the root