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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of proteolysis
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Accession:GO:0030162 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
Synonyms:exact_synonym: regulation of peptidolysis


show annotations for term's descendants           Sort by:
regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C2CD3 C2 domain containing 3 centriole elongation regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3821640|PMID:19004860) MGI
Ensembl		 PMID:19004860 GO_REF:0000107 MGI:3821640 NCBI chr11:69,085,434...69,244,791 JBrowse link
G GSAP gamma-secretase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:69,231,374...69,340,215
Ensembl chr 7:83,043,730...83,146,026 		JBrowse link
G PARL presenilin associated rhomboid like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,862,434...180,921,197
Ensembl chr 3:189,032,816...189,088,036 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3051935|PMID:15136151) MGI
Ensembl		 PMID:15136151 GO_REF:0000107 MGI:3051935 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G TRAF3 TNF receptor associated factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:83,392,689...83,530,974
Ensembl chr14:103,263,440...103,340,670 		JBrowse link
activation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939 		JBrowse link
G ASPH aspartate beta-hydroxylase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:57,921,580...58,134,778
Ensembl chr 8:59,629,707...59,843,658 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G CASP6 caspase 6 involved_in ISO (PMID:9922454) ComplexPortal PMID:9922454 NCBI chr 4:102,186,215...102,201,992
Ensembl chr 4:112,753,988...112,768,836 		JBrowse link
G CASP8 caspase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468 		JBrowse link
G CASP9 caspase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:152,667,136...152,796,575
Ensembl chr 5:159,292,029...159,418,077 		JBrowse link
G FADD Fas associated via death domain involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr11:65,300,889...65,305,020 JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424 		JBrowse link
G LGMN legumain involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:73,337,607...73,383,462
Ensembl chr14:92,677,608...92,723,051 		JBrowse link
G LOC100986481 cytochrome c involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:32,241,782...32,284,041
Ensembl chr2A:32,954,185...32,996,465 		JBrowse link
G NLRP6 NLR family pyrin domain containing 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6453663|PMID:30248149) MGI
Ensembl		 PMID:30248149 GO_REF:0000107 MGI:6453663 NCBI chr11:274,904...281,590
Ensembl chr11:319,082...325,888 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:10349840 RGD:9835366 NCBI chr12:77,114,282...77,224,116
Ensembl chr12:79,969,517...80,070,796 		JBrowse link
G PERP p53 apoptosis effector related to PMP22 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:135,845,845...135,863,603
Ensembl chr 6:139,931,031...139,947,792 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RIPK2 receptor interacting serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:86,447,216...86,480,511
Ensembl chr 8:88,398,468...88,456,268 		JBrowse link
G TBC1D10A TBC1 domain family member 10A involved_in ISO (PMID:18387192) BHF-UCL PMID:18387192 NCBI chr22:11,328,159...11,363,009
Ensembl chr22:29,130,096...29,164,865 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACER2 alkaline ceramidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:19,216,891...19,262,477
Ensembl chr 9:19,709,402...19,750,896 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:119,256,425...119,292,612
Ensembl chr  X:129,550,287...129,586,271 		JBrowse link
G ANP32B acidic nuclear phosphoprotein 32 family member B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:69,075,972...69,108,178
Ensembl chr 9:97,207,823...97,228,542 		JBrowse link
G APAF1 apoptotic peptidase activating factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3575207|PMID:15776018)
(MGI:3577148|PMID:15703386)		 MGI
Ensembl		 PMID:15703386 PMID:15776018 GO_REF:0000107 MGI:3575207 MGI:3577148 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:3,992,088...4,013,998
Ensembl chr17:3,965,925...3,998,382 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (MGI:2667259|PMID:12847083), (MGI:3575207|PMID:15776018)
(MGI:3662939|PMID:16893972)		 MGI PMID:12847083 PMID:15776018 PMID:16893972 MGI:2667259 MGI:3575207 MGI:3662939 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2667259|PMID:12847083), (MGI:3575207|PMID:15776018)
(MGI:3041326|PMID:14561915)
(MGI:3692043|PMID:14502238)		 MGI
Ensembl		 PMID:12847083 PMID:14502238 PMID:14561915 PMID:15776018 GO_REF:0000107 MGI:2667259 MGI:3041326 MGI:3575207 MGI:3692043 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G BBC3 BCL2 binding component 3 involved_in ISO (PMID:11463392), (PMID:17024184) UniProt PMID:11463392 PMID:17024184 NCBI chr19:44,203,517...44,215,860 JBrowse link
G BCL2L11 BCL2 like 11 involved_in ISO (PMID:21671007) UniProt PMID:21671007 NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079 		JBrowse link
G BID BH3 interacting domain death agonist acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2183141|PMID:12011074) MGI
Ensembl
UniProt		 PMID:12011074 GO_REF:0000104 GO_REF:0000107 MGI:2183141 NCBI chr22:1,164,787...1,205,051
Ensembl chr22:16,594,186...16,632,844 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238 		JBrowse link
G CASP10 caspase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:88,440,199...88,479,277
Ensembl chr2B:206,595,776...206,641,775 		JBrowse link
G CASP8 caspase 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2183141|PMID:12011074) MGI
Ensembl		 PMID:12011074 GO_REF:0000107 MGI:2183141 NCBI chr2B:88,490,611...88,542,132
Ensembl chr2B:206,669,544...206,696,468 		JBrowse link
G CASP8AP2 caspase 8 associated protein 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:17245429)
(MGI:1347587|PMID:10235259)		 UniProt
MGI		 PMID:10235259 PMID:17245429 MGI:1347587 NCBI chr 6:87,707,152...87,754,836
Ensembl chr 6:90,996,127...91,023,757 		JBrowse link
G CASP9 caspase 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3575207|PMID:15776018) MGI
Ensembl		 PMID:15776018 GO_REF:0000107 MGI:3575207 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G CCK cholecystokinin ISO RGD PMID:11964411 RGD:625521 NCBI chr 3:42,168,012...42,176,358
Ensembl chr 3:42,431,022...42,439,396 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in ISO (PMID:12082630) BHF-UCL PMID:12082630 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G COL4A3 collagen type IV alpha 3 chain involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:114,410,703...114,559,336
Ensembl chr2B:233,294,783...233,371,021 		JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain acts_upstream_of_or_within ISO (MGI:3603971|PMID:16183742) MGI PMID:16183742 MGI:3603971 NCBI chr12:91,220,813...91,593,799 JBrowse link
G DAP death associated protein involved_in ISO (PMID:1087798) UniProt PMID:1087798 NCBI chr 5:10,991,599...11,078,154
Ensembl chr 5:10,846,394...10,927,869 		JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2183141|PMID:12011074), (MGI:3587135|PMID:16085184)
(MGI:3587135|PMID:16085184)		 MGI
Ensembl
InterPro		 PMID:12011074 PMID:16085184 GO_REF:0000002 GO_REF:0000107 MGI:2183141 MGI:3587135 NCBI chr12:119,808,718...119,829,378
Ensembl chr12:123,176,405...123,196,359 		JBrowse link
G DLC1 DLC1 Rho GTPase activating protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:12,282,190...12,809,770
Ensembl chr 8:9,037,742...9,460,233 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:10411904) UniProt PMID:10411904 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786 		JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:14,689,398...14,716,301
Ensembl chr14:32,880,324...32,907,241 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 acts_upstream_of_or_within ISO (MGI:1858648|PMID:10882126) MGI PMID:10882126 MGI:1858648 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468 		JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,565,957...38,585,725
Ensembl chr 5:39,110,170...39,129,688 		JBrowse link
G F3 coagulation factor III, tissue factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:97,190,381...97,203,076
Ensembl chr 1:95,918,502...95,931,050 		JBrowse link
G FAM162A family with sequence similarity 162 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:119,474,737...119,500,668
Ensembl chr 3:126,380,525...126,406,366 		JBrowse link
G FASLG Fas ligand acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19364818) MGI
Ensembl		 PMID:19364818 GO_REF:0000107 NCBI chr 1:148,159,826...148,167,785
Ensembl chr 1:151,868,430...151,876,281 		JBrowse link
G HIP1 huntingtin interacting protein 1 acts_upstream_of_or_within ISO (PMID:11788820) MGI PMID:11788820 NCBI chr 7:68,281,899...68,464,233 JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:120,438,841...120,467,489
Ensembl chr12:124,685,091...124,700,726 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:84,729,615...84,743,352
Ensembl chr2B:202,623,497...202,636,959 		JBrowse link
G IFT57 intraflagellar transport 57 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:11788820) MGI
Ensembl		 PMID:11788820 GO_REF:0000107 NCBI chr 3:105,287,086...105,348,872
Ensembl chr 3:112,222,128...112,282,069 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G LAPTM5 lysosomal protein transmembrane 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,005,941...30,031,366
Ensembl chr 1:31,032,963...31,058,385 		JBrowse link
G LCK LCK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:31,560,229...31,572,391
Ensembl chr 1:32,565,739...32,579,923 		JBrowse link
G MTCH1 mitochondrial carrier 1 involved_in ISO (PMID:12377771) UniProt PMID:12377771 NCBI chr 6:36,530,002...36,548,412 JBrowse link
G MUL1 mitochondrial E3 ubiquitin protein ligase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:19,454,792...19,463,527
Ensembl chr 1:20,496,356...20,505,281 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor acts_upstream_of_or_within ISO (MGI:2677658|PMID:14517295) MGI PMID:14517295 MGI:2677658 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G NGF nerve growth factor involved_in ISO (PMID:11927634) ARUK-UCL PMID:11927634 NCBI chr 1:87,223,597...87,276,759 JBrowse link
G NGFR nerve growth factor receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:8,089,600...8,109,361
Ensembl chr17:8,075,316...8,094,966 		JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:22,926,145...22,930,396
Ensembl chr 8:19,863,275...19,864,942 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:32,241,782...32,284,041
Ensembl chr2A:32,954,185...32,996,465 		JBrowse link
G NLRP1 NLR family pyrin domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:5,562,129...5,667,765
Ensembl chr17:5,542,007...5,623,091 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 acts_upstream_of_or_within ISO (MGI:3697006|PMID:17008311) MGI PMID:17008311 MGI:3697006 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10329646) MGI
Ensembl		 PMID:10329646 GO_REF:0000107 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G P2RX1 purinergic receptor P2X 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3640029|PMID:16325464) MGI
Ensembl		 PMID:16325464 GO_REF:0000107 MGI:3640029 NCBI chr17:3,944,636...3,965,260
Ensembl chr17:3,935,982...3,956,595 		JBrowse link
G PDCD2 programmed cell death 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:168,735,480...168,745,897
Ensembl chr 6:173,821,474...173,830,459 		JBrowse link
G PDCD6 programmed cell death 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2684521|PMID:14561754) MGI
Ensembl		 PMID:14561754 GO_REF:0000107 MGI:2684521 NCBI chr 5:250,025...291,055 JBrowse link
G PIDD1 p53-induced death domain protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3603971|PMID:16183742) MGI
Ensembl		 PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chr11:816,629...827,295
Ensembl chr11:860,899...867,436 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449 		JBrowse link
G PML PML nuclear body scaffold acts_upstream_of_or_within ISO (MGI:1306978|PMID:9806545) MGI PMID:9806545 MGI:1306978 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:18293083) BHF-UCL PMID:18293083 NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060 		JBrowse link
G PYCARD PYD and CARD domain containing acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3697006|PMID:17008311) MGI
Ensembl		 PMID:17008311 GO_REF:0000107 MGI:3697006 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:176,462,991...176,470,153
Ensembl chr 5:183,712,665...183,720,128 		JBrowse link
G RET ret proto-oncogene involved_in ISO (PMID:10921886) UniProt PMID:10921886 NCBI chr10:40,050,396...40,103,629
Ensembl chr10:43,249,468...43,284,331 		JBrowse link
G RNF7 ring finger protein 7 acts_upstream_of_or_within ISO (MGI:1333612|PMID:10082581) MGI PMID:10082581 MGI:1333612 NCBI chr 3:138,772,581...138,780,763
Ensembl chr 3:146,369,779...146,377,233 		JBrowse link
G ROBO1 roundabout guidance receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:78,707,802...79,876,519
Ensembl chr 3:80,581,388...81,569,308 		JBrowse link
G RPS27L ribosomal protein S27 like involved_in ISO (PMID:17057733) UniProt PMID:17057733 NCBI chr15:42,101,137...42,105,019
Ensembl chr15:60,397,131...60,400,643 		JBrowse link
G S100A8 S100 calcium binding protein A8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:128,741,378...128,742,520
Ensembl chr 1:132,370,435...132,371,591 		JBrowse link
G S100A9 S100 calcium binding protein A9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:128,709,175...128,712,461
Ensembl chr 1:132,338,246...132,341,497 		JBrowse link
G SENP1 SUMO specific peptidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:40,624,200...40,689,837
Ensembl chr12:41,507,348...41,558,969 		JBrowse link
G SLC11A2 solute carrier family 11 member 2 involved_in ISO (PMID:18082289) UniProt PMID:18082289 NCBI chr12:37,726,158...37,774,554
Ensembl chr12:38,629,686...38,677,377 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5508628|PMID:16858406) MGI
Ensembl		 PMID:16858406 GO_REF:0000107 MGI:5508628 NCBI chr 9:4,323,124...4,420,193
Ensembl chr 9:4,511,491...4,608,337 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 acts_upstream_of ISO PMID:30120945 ARUK-UCL PMID:30120945 RGD:30309911 NCBI chr 6:158,058,226...158,150,917
Ensembl chr 6:163,065,317...163,158,931 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
G STAT1 signal transducer and activator of transcription 1 involved_in ISO (MGI:5447631|PMID:10692450) UniProt PMID:10692450 MGI:5447631 NCBI chr2B:78,270,642...78,316,074
Ensembl chr2B:196,186,906...196,232,280 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3603971|PMID:16183742) MGI
Ensembl		 PMID:16183742 GO_REF:0000107 MGI:3603971 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TNFSF15 TNF superfamily member 15 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11911831) RGD
Ensembl
MGI		 PMID:11911831 GO_REF:0000107 RGD:634236 NCBI chr 9:85,881,800...85,904,191
Ensembl chr 9:114,249,472...114,265,441 		JBrowse link
G VCP valosin containing protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2684521|PMID:14561754) MGI
Ensembl		 PMID:14561754 GO_REF:0000107 MGI:2684521 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
G XDH xanthine dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APAF1 apoptotic peptidase activating factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:96,224,515...96,311,246
Ensembl chr12:99,637,622...99,726,939 		JBrowse link
G BAK1 BCL2 antagonist/killer 1 acts_upstream_of_or_within ISO (MGI:2178486|PMID:11836241) MGI PMID:11836241 MGI:2178486 NCBI chr 6:33,146,998...33,154,755
Ensembl chr 6:34,255,769...34,263,211 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2178486|PMID:11836241)
(MGI:1203837|PMID:9560217)		 MGI
Ensembl		 PMID:9560217 PMID:11836241 GO_REF:0000107 MGI:1203837 MGI:2178486 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G BOK BCL2 family apoptosis regulator BOK involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:128,832,458...128,847,918
Ensembl chr2B:247,626,494...247,640,238 		JBrowse link
G CASP9 caspase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:14,630,659...14,662,865
Ensembl chr 1:15,624,666...15,656,266 		JBrowse link
G COPS5 COP9 signalosome subunit 5 involved_in ISO (PMID:24091666) AgBase PMID:24091666 NCBI chr 8:63,586,062...63,605,213
Ensembl chr 8:65,247,950...65,266,511 		JBrowse link
G DIABLO diablo IAP-binding mitochondrial protein acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2681362|PMID:14623868) MGI
Ensembl		 PMID:14623868 GO_REF:0000107 MGI:2681362 NCBI chr12:119,808,718...119,829,378
Ensembl chr12:123,176,405...123,196,359 		JBrowse link
G LOC100986481 cytochrome c acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1858667|PMID:10830166)
(MGI:2681362|PMID:14623868)
(MGI:3580764|PMID:15907471)		 MGI
Ensembl		 PMID:10830166 PMID:14623868 PMID:15907471 GO_REF:0000107 MGI:1858667 MGI:2681362 MGI:3580764 NCBI chr 7:25,784,900...25,791,598
Ensembl chr 7:25,396,013...25,398,549 		JBrowse link
activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1344924|PMID:10479688) MGI
Ensembl		 PMID:10479688 GO_REF:0000107 MGI:1344924 NCBI chr19:45,955,926...45,962,870
Ensembl chr19:54,793,594...54,800,468 		JBrowse link
G JAK2 Janus kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G SMAD3 SMAD family member 3 ISO TGF-beta1-induced cleavage of BAD to its more active 15 kD form RGD PMID:11839804 RGD:2301029 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185 		JBrowse link
Factor XII activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G HPSE heparanase involved_in ISO (PMID:20634491) ComplexPortal PMID:20634491 NCBI chr 4:40,863,491...40,905,693
Ensembl chr 4:46,709,621...46,755,157 		JBrowse link
G KNG1 kininogen 1 ISO RGD PMID:6685967 RGD:11062094 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149 		JBrowse link
inhibition of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARD16 caspase recruitment domain family member 16 involved_in ISO (PMID:11432859) UniProt PMID:11432859 NCBI chr11:99,981,854...99,985,839 JBrowse link
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CAST calpastatin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650 		JBrowse link
G CST7 cystatin F acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5904382|PMID:28251676) MGI
Ensembl		 PMID:28251676 GO_REF:0000107 MGI:5904382 NCBI chr20:24,889,834...24,900,766
Ensembl chr20:25,237,251...25,248,364 		JBrowse link
G LOC100969375 caspase recruitment domain-containing protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,204,735...45,256,481
Ensembl chr19:53,798,967...53,850,328 		JBrowse link
G NOL3 nucleolar protein 3 involved_in ISO PMID:16639714 UniProt PMID:16639714 RGD:10047164 NCBI chr16:47,516,156...47,521,441
Ensembl chr16:66,904,738...66,909,956 		JBrowse link
G XIAP X-linked inhibitor of apoptosis involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606 		JBrowse link
inhibition of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2L12 BCL2 like 12 involved_in ISO (PMID:22262180) UniProt PMID:22262180 NCBI chr19:46,679,749...46,688,539 JBrowse link
G FCMR Fc fragment of IgM receptor acts_upstream_of_or_within ISO (MGI:3576402|PMID:15632112) MGI PMID:15632112 MGI:3576402 NCBI chr 1:182,506,551...182,525,249
Ensembl chr 1:186,786,147...186,803,789 		JBrowse link
G NOL3 nucleolar protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,516,156...47,521,441
Ensembl chr16:66,904,738...66,909,956 		JBrowse link
G XIAP X-linked inhibitor of apoptosis acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2681362|PMID:14623868) MGI
Ensembl		 PMID:14623868 GO_REF:0000107 MGI:2681362 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606 		JBrowse link
negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:33,168,767...33,228,075
Ensembl chr2B:127,716,550...127,775,378 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432 		JBrowse link
G TMED10 transmembrane p24 trafficking protein 10 acts_upstream_of_or_within ISO (MGI:3623864|PMID:16641999) MGI PMID:16641999 MGI:3623864 NCBI chr14:55,683,121...55,728,365
Ensembl chr14:74,526,733...74,572,000 		JBrowse link
negative regulation of aspartic-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLRP7 NLR family pyrin domain containing 7 involved_in ISO (PMID:15817483) UniProt PMID:15817483 NCBI chr19:51,966,886...51,990,971
Ensembl chr19:60,662,184...60,677,844 		JBrowse link
negative regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSN2 casein beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:54,276,495...54,282,221
Ensembl chr 4:60,613,091...60,618,815 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 ISO RGD PMID:23690069 RGD:13792722 NCBI chr11:62,624,647...62,644,846
Ensembl chr11:65,939,164...65,959,066 		JBrowse link
G HTT huntingtin ISO RGD PMID:17124493 RGD:6902918 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730 		JBrowse link
G IFI16 interferon gamma inducible protein 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:134,364,706...134,405,910
Ensembl chr 1:138,152,328...138,203,424 		JBrowse link
G LTF lactotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:46,337,738...46,367,476
Ensembl chr 3:47,442,440...47,471,532 		JBrowse link
G MT3 metallothionein 3 involved_in ISO (PMID:18554677) UniProt PMID:18554677 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093 		JBrowse link
G PCID2 PCI domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:94,319,699...94,350,763
Ensembl chr13:113,388,251...113,419,251 		JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2A adenosine A2a receptor ISO RGD PMID:15211592 RGD:1625666 NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO caspase 3 RGD PMID:18348079 RGD:2313324 NCBI chr19:37,275,799...37,331,971
Ensembl chr19:45,791,800...45,840,271 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141 		JBrowse link
G ARL6IP1 ADP ribosylation factor like GTPase 6 interacting protein 1 involved_in ISO (PMID:12754298) UniProt PMID:12754298 NCBI chr16:19,478,719...19,488,636 JBrowse link
G ARRB1 arrestin beta 1 involved_in ISO (MGI:4453294|PMID:19915011) UniProt PMID:19915011 MGI:4453294 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ARRB2 arrestin beta 2 ISO RGD PMID:19171933 RGD:5510006 NCBI chr17:4,766,616...4,777,253
Ensembl chr17:4,757,048...4,767,517 		JBrowse link
G AVP arginine vasopressin involved_in ISO (PMID:18402937) UniProt PMID:18402937 NCBI chr20:3,169,094...3,172,900 JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 involved_in ISO (PMID:9859993)
(PMID:12773388)		 UniProt PMID:9859993 PMID:12773388 NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159 		JBrowse link
G CARD16 caspase recruitment domain family member 16 involved_in ISO (PMID:16920334) UniProt PMID:16920334 NCBI chr11:99,981,854...99,985,839 JBrowse link
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CD44 CD44 molecule (Indian blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:35,110,732...35,258,238
Ensembl chr11:34,985,634...35,079,009 		JBrowse link
G CDKN2D cyclin dependent kinase inhibitor 2D involved_in ISO (PMID:15750620) BHF-UCL PMID:15750620 NCBI chr19:10,118,302...10,120,957 JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator acts_upstream_of_or_within ISO (MGI:3612311|PMID:16263940) MGI PMID:16263940 MGI:3612311 NCBI chr2B:88,373,057...88,429,959
Ensembl chr2B:206,528,943...206,577,045 		JBrowse link
G CRYAB crystallin alpha B acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3617146|PMID:16439475) MGI
Ensembl		 PMID:16439475 GO_REF:0000107 MGI:3617146 NCBI chr11:106,795,406...106,800,019
Ensembl chr11:110,639,442...110,644,272 		JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:16193064) UniProt PMID:16193064 NCBI chr20:689,494...752,092
Ensembl chr20:456,629...521,126 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,780,381...33,796,829
Ensembl chr  X:41,475,116...41,505,837 		JBrowse link
G DHCR24 24-dehydrocholesterol reductase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:54,126,170...54,163,713
Ensembl chr 1:55,714,693...55,754,698 		JBrowse link
G DNAJA3 DnaJ heat shock protein family (Hsp40) member A3 involved_in ISO (PMID:10411904) UniProt PMID:10411904 NCBI chr16:3,351,825...3,381,914
Ensembl chr16:4,519,965...4,550,786 		JBrowse link
G DNAJB6 DnaJ heat shock protein family (Hsp40) member B6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:148,952,823...149,034,578
Ensembl chr 7:160,646,321...160,726,447 		JBrowse link
G DPEP1 dipeptidase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:70,365,900...70,392,377
Ensembl chr16:89,975,105...89,997,978 		JBrowse link
G EP300 E1A binding protein p300 ISO cardiac myocytes RGD PMID:22562121 RGD:7327216 NCBI chr22:21,986,467...22,076,921
Ensembl chr22:40,079,503...40,168,604 		JBrowse link
G FABP1 fatty acid binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:87,256,032...87,303,505
Ensembl chr2A:89,165,315...89,170,448 		JBrowse link
G FNIP1 folliculin interacting protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5444323|PMID:22709692) MGI
Ensembl		 PMID:22709692 GO_REF:0000107 MGI:5444323 NCBI chr 5:127,070,906...127,219,548
Ensembl chr 5:133,235,501...133,384,218 		JBrowse link
G GPI glucose-6-phosphate isomerase ISO RGD PMID:12615053 RGD:1600634 NCBI chr19:31,301,469...31,355,362
Ensembl chr19:40,024,584...40,080,598 		JBrowse link
G GPX1 glutathione peroxidase 1 involved_in ISO (PMID:12221075) BHF-UCL PMID:12221075 NCBI chr 3:49,280,038...49,281,455
Ensembl chr 3:50,360,947...50,361,826 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 ISO RGD PMID:15102845 RGD:1304324 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164 		JBrowse link
G HGF hepatocyte growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:73,667,618...73,738,960
Ensembl chr 7:87,327,798...87,397,811 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:21874357 RGD:150540304 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
G IFI6 interferon alpha inducible protein 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,929,129...26,935,205
Ensembl chr 1:27,972,866...27,978,890 		JBrowse link
G IGBP1 immunoglobulin binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:59,401,426...59,434,363
Ensembl chr  X:69,460,734...69,493,616 		JBrowse link
G IGF1 insulin like growth factor 1 involved_in ISO PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IL24 interleukin 24 acts_upstream_of_or_within ISO (MGI:3821693|PMID:18708357) MGI PMID:18708357 MGI:3821693 NCBI chr 1:182,500,680...182,507,098
Ensembl chr 1:186,779,207...186,785,928 		JBrowse link
G IL6 interleukin 6 ISO RGD PMID:19061939 RGD:2306937 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G INTS1 integrator complex subunit 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3722560|PMID:17544522) MGI
Ensembl		 PMID:17544522 GO_REF:0000107 MGI:3722560 NCBI chr 7:1,719,254...1,753,150
Ensembl chr 7:1,838,302...1,871,554 		JBrowse link
G KLF4 KLF transcription factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:78,634,545...78,639,447
Ensembl chr 9:106,820,954...106,825,797 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,152,363...180,193,223
Ensembl chr 3:188,324,660...188,363,268 		JBrowse link
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:113,050,671...113,057,368
Ensembl chr 1:127,285,553...127,292,233 		JBrowse link
G LOC100990437 NADPH--cytochrome P450 reductase ISO caspase-3 RGD PMID:19264869 RGD:2316785 NCBI chr 7:68,035,021...68,105,934
Ensembl chr 7:82,364,418...82,437,530 		JBrowse link
G MAP2K5 mitogen-activated protein kinase kinase 5 involved_in ISO PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr15:46,493,139...46,760,271
Ensembl chr15:64,761,394...65,029,655 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-2, caspase-3 RGD PMID:19850968 RGD:2317361 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:107,247,084...107,269,138
Ensembl chr 6:111,295,548...111,317,214 		JBrowse link
G MRTFA myocardin related transcription factor A acts_upstream_of_or_within ISO (MGI:2183867|PMID:12019265) MGI PMID:12019265 MGI:2183867 NCBI chr22:21,314,829...21,536,673
Ensembl chr22:39,413,002...39,467,402 		JBrowse link
G MT3 metallothionein 3 involved_in ISO (PMID:16387743) UniProt PMID:16387743 NCBI chr16:36,875,919...36,877,558
Ensembl chr16:56,007,922...56,028,093 		JBrowse link
G NAIP NLR family apoptosis inhibitory protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:44,345,623...44,401,358
Ensembl chr 5:45,920,125...45,973,937 		JBrowse link
G NOL3 nucleolar protein 3 involved_in ISO PMID:19001025 UniProt PMID:19001025 RGD:8553292 NCBI chr16:47,516,156...47,521,441
Ensembl chr16:66,904,738...66,909,956 		JBrowse link
G NR4A1 nuclear receptor subfamily 4 group A member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2667579|PMID:12815108) MGI
Ensembl		 PMID:12815108 GO_REF:0000107 MGI:2667579 NCBI chr12:36,703,903...36,740,211
Ensembl chr12:37,480,300...37,501,188 		JBrowse link
G PAX2 paired box 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:97,344,978...97,429,086
Ensembl chr10:100,822,676...100,904,028 		JBrowse link
G PTGER2 prostaglandin E receptor 2 involved_in ISO (PMID:21716255) CAFA PMID:21716255 NCBI chr14:32,910,755...32,926,138
Ensembl chr14:51,195,381...51,209,686 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:162,205,534...162,214,130
Ensembl chr 1:166,355,845...166,364,519 		JBrowse link
G PTMA prothymosin alpha ISO RGD PMID:12522243 RGD:734494 NCBI chr2B:118,959,382...118,964,364 JBrowse link
G RAG1 recombination activating 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3531056|PMID:15728238) MGI
Ensembl		 PMID:15728238 GO_REF:0000107 MGI:3531056 NCBI chr11:36,483,697...36,546,242
Ensembl chr11:36,412,420...36,422,904 		JBrowse link
G RPS6KA1 ribosomal protein S6 kinase A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:25,792,428...25,837,950
Ensembl chr 1:26,856,057...26,900,532 		JBrowse link
G RPS6KA3 ribosomal protein S6 kinase A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:12,772,368...12,893,062
Ensembl chr  X:20,133,898...20,251,244 		JBrowse link
G SFN stratifin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:26,126,212...26,127,761
Ensembl chr 1:27,182,834...27,183,580 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3702339|PMID:17251350) MGI
Ensembl		 PMID:17251350 GO_REF:0000107 MGI:3702339 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:161,319,093...161,495,917
Ensembl chr 4:173,394,739...173,567,096 		JBrowse link
G SIAH2 siah E3 ubiquitin protein ligase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:147,759,375...147,781,639
Ensembl chr 3:155,332,751...155,354,139 		JBrowse link
G SNCA synuclein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
G TNF tumor necrosis factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:31124343) ARUK-UCL
Ensembl		 PMID:31124343 GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TRIAP1 TP53 regulated inhibitor of apoptosis 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:118,025,599...118,028,045
Ensembl chr12:121,400,063...121,402,506 		JBrowse link
G USP47 ubiquitin specific peptidase 47 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:12,009,770...12,127,425
Ensembl chr11:11,703,617...11,821,074 		JBrowse link
G VEGFA vascular endothelial growth factor A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353 		JBrowse link
G WNT9A Wnt family member 9A acts_upstream_of_or_within ISO (MGI:4368092|PMID:19422823) MGI PMID:19422823 MGI:4368092 NCBI chr 1:203,320,990...203,350,599
Ensembl chr 1:208,300,609...208,327,191 		JBrowse link
G XIAP X-linked inhibitor of apoptosis acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2183141|PMID:12011074), (MGI:2183348|PMID:12153481) MGI
Ensembl		 PMID:12011074 PMID:12153481 GO_REF:0000107 MGI:2183141 MGI:2183348 NCBI chr  X:113,052,164...113,105,160
Ensembl chr  X:123,232,643...123,278,606 		JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAAP1 caspase activity and apoptosis inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:26,688,023...26,739,818
Ensembl chr 9:27,295,433...27,346,814 		JBrowse link
G IL9 interleukin 9 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4367548|PMID:18551134) MGI
Ensembl		 PMID:18551134 GO_REF:0000107 MGI:4367548 NCBI chr 5:131,283,170...131,289,777
Ensembl chr 5:137,425,367...137,428,945 		JBrowse link
G LOC100991889 interleukin-9 receptor acts_upstream_of_or_within ISO (MGI:4367548|PMID:18551134) MGI PMID:18551134 MGI:4367548 NCBI chr 9:109,268,011...109,277,418
Ensembl chr  X:155,373,324...155,386,631 		JBrowse link
G MMP9 matrix metallopeptidase 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:42,346,305...42,354,018
Ensembl chr20:43,432,389...43,440,129 		JBrowse link
G NLE1 notchless homolog 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5468737|PMID:23231322) MGI
Ensembl		 PMID:23231322 GO_REF:0000107 MGI:5468737 NCBI chr17:21,643,865...21,654,169
Ensembl chr17:21,935,800...21,946,049 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PIH1D1 PIH1 domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,459,855...46,465,882
Ensembl chr19:55,381,803...55,387,664 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:40,588,100...40,616,479
Ensembl chr19:49,197,341...49,222,561
Ensembl chr19:49,197,341...49,222,561 		JBrowse link
negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PAK2 p21 (RAC1) activated kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,084,037...194,174,010
Ensembl chr 3:204,023,357...204,111,507 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:21,696,808...21,779,878
Ensembl chr17:22,035,643...22,069,546 		JBrowse link
G RNF34 ring finger protein 34 involved_in ISO (PMID:15069192) UniProt PMID:15069192 NCBI chr12:118,998,436...119,022,823
Ensembl chr12:122,373,172...122,402,693 		JBrowse link
negative regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G CRB2 crumbs cell polarity complex component 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:94,473,423...94,511,285
Ensembl chr 9:123,011,968...123,032,855 		JBrowse link
G FETUB fetuin B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:183,675,258...183,687,754
Ensembl chr 3:192,142,702...192,154,920 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,665,218...6,669,170
Ensembl chr12:6,583,895...6,587,729 		JBrowse link
G LOC100991849 glyceraldehyde-3-phosphate dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:5,279,765...5,281,053
Ensembl chr12:6,583,895...6,587,729 		JBrowse link
G PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:41,128,785...41,133,284
Ensembl chr  X:48,988,948...48,990,028 		JBrowse link
G RENBP renin binding protein ISO RGD PMID:11926999 RGD:727355 NCBI chr  X:143,490,103...143,499,487
Ensembl chr  X:153,376,847...153,386,214 		JBrowse link
G SERPINB1 serpin family B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,655,244...2,664,074
Ensembl chr 6:2,758,173...2,766,650 		JBrowse link
G SERPINB13 serpin family B member 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:56,946,828...56,958,702
Ensembl chr18:60,258,085...60,270,607 		JBrowse link
G SERPINB6 serpin family B member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,770,689...2,794,737
Ensembl chr 6:2,873,790...2,896,631 		JBrowse link
G SERPINB8 serpin family B member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:57,313,562...57,373,502
Ensembl chr18:60,634,206...60,669,118 		JBrowse link
G SERPINB9 serpin family B member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:2,709,188...2,725,592
Ensembl chr 6:2,812,815...2,827,932 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:10717410 GO_REF:0000107 RGD:8547889 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SPOCK1 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:132,372,283...132,890,168
Ensembl chr 5:138,512,523...138,797,416 		JBrowse link
G SPOCK3 SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3 involved_in ISO (PMID:11751414) UniProt PMID:11751414 NCBI chr 4:158,941,142...159,437,078
Ensembl chr 4:171,022,442...171,517,005 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419 		JBrowse link
G VTN vitronectin involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,403,813...28,407,202
Ensembl chr17:28,906,508...28,909,583 		JBrowse link
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440 		JBrowse link
G SVIP small VCP interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:22,828,321...22,837,536
Ensembl chr11:22,735,361...22,744,558 		JBrowse link
G USP14 ubiquitin specific peptidase 14 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:14,104,754...14,158,402
Ensembl chr18:17,745,733...17,797,070 		JBrowse link
negative regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP11 aquaporin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:72,653,721...72,673,698
Ensembl chr11:76,295,778...76,315,292 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404 		JBrowse link
G USP25 ubiquitin specific peptidase 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:2,468,993...2,618,200
Ensembl chr21:15,724,729...15,982,182 		JBrowse link
negative regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:182,369,234...182,374,207
Ensembl chr 1:186,648,289...186,653,371 		JBrowse link
G PTPN3 protein tyrosine phosphatase non-receptor type 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:80,528,896...80,651,629
Ensembl chr 9:108,699,761...108,787,464 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964 		JBrowse link
negative regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RECK reversion inducing cysteine rich protein with kazal motifs involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 9:35,886,741...35,974,133
Ensembl chr 9:36,699,631...36,774,116 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964 		JBrowse link
negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:81,011,324...81,122,352
Ensembl chr11:84,619,241...84,730,684 		JBrowse link
G SORL1 sortilin related receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:116,297,014...116,477,399
Ensembl chr11:120,222,491...120,402,432 		JBrowse link
negative regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
negative regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2ML1 alpha-2-macroglobulin like 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr12:8,909,111...8,961,857
Ensembl chr12:9,122,447...9,192,371 		JBrowse link
G APLP2 amyloid beta precursor like protein 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr11:124,881,191...124,944,472
Ensembl chr11:128,775,329...128,847,482 		JBrowse link
G APP amyloid beta precursor protein involved_in IEA UniProt GO_REF:0000043 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G CAST calpastatin acts_upstream_of_or_within ISO (MGI:5295525|PMID:21849499) MGI PMID:21849499 MGI:5295525 NCBI chr 5:91,972,572...92,084,657
Ensembl chr 5:97,527,071...97,636,650 		JBrowse link
G CD109 CD109 molecule involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:71,519,293...71,654,300
Ensembl chr 6:74,801,384...74,937,414 		JBrowse link
G CPAMD8 C3 and PZP like alpha-2-macroglobulin domain containing 8 involved_in IEA UniProt GO_REF:0000043 NCBI chr19:16,379,956...16,513,841
Ensembl chr19:17,359,534...17,487,791 		JBrowse link
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425 		JBrowse link
G CST7 cystatin F involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:24,889,834...24,900,766
Ensembl chr20:25,237,251...25,248,364 		JBrowse link
G CSTA cystatin A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:119,417,489...119,432,244
Ensembl chr 3:126,323,901...126,338,430 		JBrowse link
G CSTB cystatin B involved_in IEA UniProt GO_REF:0000043 NCBI chr21:30,030,359...30,032,899 JBrowse link
G CTSB cathepsin B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:7,333,498...7,359,264 JBrowse link
G ECM1 extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:125,853,337...125,858,904
Ensembl chr 1:129,502,041...129,507,819 		JBrowse link
G ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:52,719,065...52,733,507
Ensembl chr 3:53,945,141...53,959,378 		JBrowse link
G ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:7,732,931...7,782,362
Ensembl chr10:7,713,454...7,762,756 		JBrowse link
G ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:52,733,966...52,750,198
Ensembl chr 3:53,961,451...53,976,065 		JBrowse link
G ITIH4 inter-alpha-trypsin inhibitor heavy chain 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:52,754,664...52,774,867
Ensembl chr 3:53,980,668...53,998,038 		JBrowse link
G ITIH5 inter-alpha-trypsin inhibitor heavy chain 5 involved_in IEA UniProt GO_REF:0000043 NCBI chr10:7,589,897...7,697,190
Ensembl chr10:7,570,497...7,677,254 		JBrowse link
G ITIH6 inter-alpha-trypsin inhibitor heavy chain family member 6 involved_in IEA UniProt GO_REF:0000043 NCBI chr  X:46,957,480...47,000,642
Ensembl chr  X:55,188,633...55,231,778 		JBrowse link
G LOC100979269 alpha-2-macroglobulin involved_in IEA UniProt GO_REF:0000043 NCBI chr12:9,154,457...9,202,833
Ensembl chr12:9,385,359...9,433,979 		JBrowse link
G LOC100981672 pregnancy zone protein involved_in IEA UniProt GO_REF:0000043 NCBI chr12:9,235,698...9,297,261
Ensembl chr12:9,467,327...9,527,172 		JBrowse link
G LOC100992594 eppin involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,877,561...41,884,375
Ensembl chr20:42,967,885...42,973,479 		JBrowse link
G SERPINB4 serpin family B member 4 involved_in ISO (PMID:12949073) UniProt PMID:12949073 NCBI chr18:56,996,437...57,003,489 JBrowse link
G SERPINE2 serpin family E member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3521551|PMID:15509762), (MGI:3810206|PMID:18398001) MGI
Ensembl		 PMID:15509762 PMID:18398001 GO_REF:0000107 MGI:3521551 MGI:3810206 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (MGI:72783|PMID:3428272) MGI PMID:3428272 MGI:72783 NCBI chr 5:143,273,137...143,287,745 JBrowse link
G TFPI tissue factor pathway inhibitor involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr2B:74,744,154...74,834,338
Ensembl chr2B:192,541,881...192,581,384 		JBrowse link
G TFPI2 tissue factor pathway inhibitor 2 involved_in IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr 7:85,835,141...85,839,515
Ensembl chr 7:99,426,006...99,431,099 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr  X:40,018,190...40,022,636
Ensembl chr  X:47,914,906...47,919,419 		JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 involved_in IEA UniProt GO_REF:0000043 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 3:12,079,195...12,087,485
Ensembl chr 3:12,425,429...12,433,192 		JBrowse link
G WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 involved_in IEA UniProt GO_REF:0000043 NCBI chr17:44,924,892...44,932,578
Ensembl chr17:49,797,334...49,805,569 		JBrowse link
negative regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPB2 carboxypeptidase B2 ISO RGD PMID:23369837 RGD:7243115 NCBI chr13:26,926,788...26,979,767 JBrowse link
G CTSZ cathepsin Z involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,346,241...55,358,354
Ensembl chr20:56,706,511...56,718,941 		JBrowse link
G SERPINE1 serpin family E member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,267,517...93,279,728
Ensembl chr 7:106,510,130...106,518,450 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040 		JBrowse link
G SERPINF2 serpin family F member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:1,725,469...1,738,887
Ensembl chr17:1,618,549...1,631,570 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
negative regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALAD aminolevulinate dehydratase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:84,488,339...84,503,360
Ensembl chr 9:112,859,171...112,873,784 		JBrowse link
G F8A1 coagulation factor VIII associated 1 involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:144,366,123...144,367,842 JBrowse link
G F8A2 coagulation factor VIII associated 2 involved_in ISO (PMID:27815841) UniProt PMID:27815841 NCBI chr  X:144,851,466...144,853,185 JBrowse link
G GABARAPL2 GABA type A receptor associated protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:56,135,482...56,147,046
Ensembl chr16:75,483,459...75,495,019 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 involved_in ISO (MGI:6148636|PMID:17517623) ARUK-UCL PMID:17517623 MGI:6148636 RGD:13514081 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872 		JBrowse link
G LAMP3 lysosomal associated membrane protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:180,152,363...180,193,223
Ensembl chr 3:188,324,660...188,363,268 		JBrowse link
G LOC100988585 transmembrane protein 220 acts_upstream_of_or_within ISO (MGI:5643882|PMID:25683716) MGI PMID:25683716 MGI:5643882 NCBI chr17:40,923,397...40,973,382
Ensembl chr17:45,703,642...45,720,520
Ensembl chr17:45,703,642...45,720,520 		JBrowse link
G MARCHF7 membrane associated ring-CH-type finger 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:47,004,211...47,059,901
Ensembl chr2B:164,377,605...164,432,907 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:57,288,297...57,674,685
Ensembl chr  X:67,359,364...67,739,114 		JBrowse link
G PRKCG protein kinase C gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:50,823,372...50,849,003
Ensembl chr19:59,672,097...59,695,977 		JBrowse link
G PSME3IP1 proteasome activator subunit 3 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,430,698...37,464,089
Ensembl chr16:56,563,353...56,596,619 		JBrowse link
G PSMF1 proteasome inhibitor subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:1,275,662...1,325,410
Ensembl chr20:1,043,513...1,092,237 		JBrowse link
G USP19 ubiquitin specific peptidase 19 involved_in ISO (MGI:5614537|PMID:25088257) ParkinsonsUK-UCL PMID:25088257 MGI:5614537 NCBI chr 3:49,032,373...49,045,238
Ensembl chr 3:50,100,216...50,125,112 		JBrowse link
negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG5 BAG cochaperone 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:84,182,879...84,189,180
Ensembl chr14:103,997,524...103,998,927 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321 		JBrowse link
G CAMLG calcium modulating ligand involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:130,138,644...130,144,540
Ensembl chr 5:136,282,910...136,295,382 		JBrowse link
G CCAR2 cell cycle and apoptosis regulator 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:21,854,803...21,870,556
Ensembl chr 8:18,794,027...18,808,571 		JBrowse link
G CLEC16A C-type lectin domain containing 16A acts_upstream_of_or_within ISO (MGI:5603233|PMID:24949970) MGI PMID:24949970 MGI:5603233 NCBI chr16:9,887,877...10,124,500
Ensembl chr16:11,109,869...11,343,512 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G EIF3H eukaryotic translation initiation factor 3 subunit H involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:113,320,059...113,440,769
Ensembl chr 8:115,863,490...115,973,872 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase involved_in ISO (PMID:15313915) UniProt PMID:15313915 NCBI chr 3:59,670,777...61,177,974 JBrowse link
G GIPC1 GIPC PDZ domain containing family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:14,041,192...14,059,402
Ensembl chr19:14,885,185...14,889,701 		JBrowse link
G HSP90AB1 heat shock protein 90 alpha family class B member 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:16280321)
(PMID:24613385)		 MGI
UniProt		 PMID:16280321 PMID:24613385 NCBI chr 6:43,842,796...43,849,637
Ensembl chr 6:45,125,773...45,133,872 		JBrowse link
G KLHL40 kelch like family member 40 acts_upstream_of_or_within ISO (MGI:5586592|PMID:24960163) MGI PMID:24960163 MGI:5586592 NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055 		JBrowse link
G MAP1A microtubule associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) ARUK-UCL PMID:26609151 MGI:5703671 NCBI chr15:22,472,641...22,493,293
Ensembl chr15:40,627,099...40,647,752 		JBrowse link
G MTM1 myotubularin 1 acts_upstream_of_or_within ISO (MGI:5510937|PMID:23695157) MGI PMID:23695157 MGI:5510937 NCBI chr  X:140,218,742...140,323,495
Ensembl chr  X:150,174,758...150,255,381 		JBrowse link
G N4BP1 NEDD4 binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:28,809,881...28,881,352
Ensembl chr16:47,698,353...47,769,755 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) UniProt PMID:22522597 NCBI chr19:44,739,739...44,751,303 JBrowse link
G OGT O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,798,219...60,840,948
Ensembl chr  X:70,852,687...70,894,921 		JBrowse link
G PANO1 proapoptotic nucleolar protein 1 involved_in ISO (PMID:22094112) UniProt PMID:22094112 NCBI chr11:814,040...816,633 JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PBK PDZ binding kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5293269|PMID:21715333) MGI
Ensembl		 PMID:21715333 GO_REF:0000107 MGI:5293269 NCBI chr 8:27,084,789...27,112,986
Ensembl chr 8:24,285,395...24,313,658 		JBrowse link
G PHF20L1 PHD finger protein 20 like 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:129,427,157...129,500,633
Ensembl chr 8:132,403,053...132,474,452 		JBrowse link
G RPL11 ribosomal protein L11 involved_in ISO (MGI:5897550|PMID:21804542) UniProt PMID:21804542 MGI:5897550 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313 		JBrowse link
G RYBP RING1 and YY1 binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:72,315,494...72,389,328
Ensembl chr 3:74,247,807...74,318,398 		JBrowse link
G SDCBP syndecan binding protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,992,627...55,022,560
Ensembl chr 8:56,643,962...56,673,833 		JBrowse link
G SENP1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO (MGI:3818351|PMID:17981124) MGI PMID:17981124 MGI:3818351 NCBI chr12:40,624,200...40,689,837
Ensembl chr12:41,507,348...41,558,969 		JBrowse link
G SHH sonic hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3624046|PMID:16611981) MGI
Ensembl		 PMID:16611981 GO_REF:0000107 MGI:3624046 NCBI chr 7:147,400,112...147,414,036
Ensembl chr 7:159,114,666...159,126,651 		JBrowse link
G SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5310666|PMID:22285184) MGI
Ensembl		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr 3:47,487,948...47,683,623
Ensembl chr 3:48,590,221...48,781,248 		JBrowse link
G TAF9 TATA-box binding protein associated factor 9 involved_in ISO (PMID:11278372) BHF-UCL PMID:11278372 NCBI chr 5:44,630,503...44,635,760 JBrowse link
G TLK2 tousled like kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:56,542,670...56,678,294
Ensembl chr17:61,689,998...61,830,394 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G TTC36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6362140|PMID:31537781) MGI
Ensembl		 PMID:31537781 GO_REF:0000107 MGI:6362140 NCBI chr11:113,364,559...113,368,586
Ensembl chr11:117,295,191...117,298,928 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404 		JBrowse link
G UCHL5 ubiquitin C-terminal hydrolase L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:168,471,501...168,519,366
Ensembl chr 1:172,764,606...172,811,880 		JBrowse link
G USP7 ubiquitin specific peptidase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:7,825,332...7,895,095
Ensembl chr16:9,065,858...9,106,146 		JBrowse link
G USP9X ubiquitin specific peptidase 9 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,535,543...33,683,220
Ensembl chr  X:41,232,041...41,379,910 		JBrowse link
G WAC WW domain containing adaptor with coiled-coil involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:28,685,294...28,777,176
Ensembl chr10:29,042,331...29,130,591 		JBrowse link
negative regulation of protein deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr2B:106,536,846...106,544,430
Ensembl chr2B:225,127,967...225,135,556 		JBrowse link
G TRIM21 tripartite motif containing 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:4,588,083...4,596,942
Ensembl chr11:4,254,152...4,262,981 		JBrowse link
negative regulation of protein K48-linked deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404 		JBrowse link
negative regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP4 acid phosphatase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:47,754,780...47,760,294
Ensembl chr19:56,649,018...56,653,909 		JBrowse link
G CDH1 cadherin 1 acts_upstream_of_or_within ISO (MGI:3763814|PMID:17344476) MGI PMID:17344476 MGI:3763814 NCBI chr16:49,108,745...49,206,347
Ensembl chr16:68,502,584...68,596,488 		JBrowse link
G CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:19,895,554...19,898,672
Ensembl chr15:38,145,730...38,148,698 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 ISO Casp3 RGD PMID:22817682 RGD:11566024 NCBI chr  X:136,937,889...136,976,828
Ensembl chr  X:147,365,748...147,405,321 		JBrowse link
G GAS1 growth arrest specific 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:58,079,700...58,082,849
Ensembl chr 9:86,139,009...86,140,045 		JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within ISO (MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:4829577 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764 		JBrowse link
G IL1R2 interleukin 1 receptor type 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5468848|PMID:23395675) MGI
Ensembl		 PMID:23395675 GO_REF:0000107 MGI:5468848 Ensembl chr2A:103,042,328...103,078,190 JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MDM2 MDM2 proto-oncogene ISO caspase-3 RGD PMID:19638633 RGD:2317364 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G NLRP7 NLR family pyrin domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:51,966,886...51,990,971
Ensembl chr19:60,662,184...60,677,844 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A ISO Casp3 RGD PMID:21925170 RGD:9999170 NCBI chr19:45,872,596...45,876,376
Ensembl chr19:54,880,141...54,883,003 		JBrowse link
G SNX12 sorting nexin 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,327,484...60,336,682
Ensembl chr  X:70,384,164...70,395,737 		JBrowse link
G TMEM59 transmembrane protein 59 involved_in ISO (PMID:20427278) UniProt PMID:20427278 NCBI chr 1:53,305,154...53,326,975
Ensembl chr 1:54,899,026...54,920,478 		JBrowse link
G TMEM98 transmembrane protein 98 involved_in ISO (MGI:6258499|PMID:30249802) UniProt PMID:30249802 MGI:6258499 NCBI chr17:23,844,747...23,858,390
Ensembl chr17:24,133,357...24,146,912 		JBrowse link
negative regulation of protein processing involved in protein targeting to mitochondrion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SIRT4 sirtuin 4 ISO RGD PMID:24029877 RGD:9586053 NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777 		JBrowse link
negative regulation of proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321 		JBrowse link
G CDK5 cyclin dependent kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:142,640,630...142,644,785
Ensembl chr 7:154,793,344...154,797,499 		JBrowse link
G CLN3 CLN3 lysosomal/endosomal transmembrane protein, battenin acts_upstream_of_or_within ISO (MGI:1346962|PMID:10527801) MGI PMID:10527801 MGI:1346962
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425 		JBrowse link
G CSTA cystatin A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:119,417,489...119,432,244
Ensembl chr 3:126,323,901...126,338,430 		JBrowse link
G CSTB cystatin B involved_in ISO (PMID:3488317) UniProt PMID:3488317 NCBI chr21:30,030,359...30,032,899 JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G HDAC6 histone deacetylase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,099,539...41,122,650
Ensembl chr  X:48,960,430...48,982,642 		JBrowse link
G IDE insulin degrading enzyme ISO inhibits activity of the multicatalytic proteinase complex (proteasome) RGD PMID:9000694 RGD:1627643 NCBI chr10:89,196,295...89,320,223
Ensembl chr10:92,716,540...92,833,353 		JBrowse link
G INS insulin involved_in ISO (PMID:3553851) BHF-UCL PMID:3553851 NCBI chr11:2,200,785...2,202,579
Ensembl chr11:2,218,117...2,231,666 		JBrowse link
G KNG1 kininogen 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:3356189 GO_REF:0000107 RGD:1600550 NCBI chr 3:183,751,598...183,778,655
Ensembl chr 3:192,219,462...192,245,149 		JBrowse link
G LOC100994116 cystatin-S involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:23,634,895...23,638,284
Ensembl chr20:23,987,931...23,991,674 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:47,340,077...47,346,737
Ensembl chr19:56,243,124...56,250,024 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,195,122...47,215,277
Ensembl chr11:47,748,353...47,768,672 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO RGD PMID:15161606 RGD:1625251 NCBI chr 5:45,701,219...45,786,652
Ensembl chr 5:47,267,286...47,350,960 		JBrowse link
G PLAT plasminogen activator, tissue type involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:41,419,415...41,451,951
Ensembl chr 8:38,864,918...38,897,779 		JBrowse link
G RAB23 RAB23, member RAS oncogene family acts_upstream_of_or_within ISO (MGI:3612806|PMID:16364285) MGI PMID:16364285 MGI:3612806 NCBI chr 6:56,744,948...56,780,187
Ensembl chr 6:58,375,559...58,411,107 		JBrowse link
G SERPINA5 serpin family A member 5 ISO RGD PMID:16088033 RGD:1580291 NCBI chr14:75,205,446...75,217,114
Ensembl chr14:94,537,115...94,548,803 		JBrowse link
G SERPINB10 serpin family B member 10 ISO RGD PMID:11986314 RGD:634009 NCBI chr18:57,262,514...57,289,744
Ensembl chr18:60,573,580...60,599,697 		JBrowse link
G SERPINE2 serpin family E member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:111,221,317...111,285,491
Ensembl chr2B:229,797,655...229,861,040 		JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3055648|PMID:15466487) MGI
Ensembl		 PMID:15466487 GO_REF:0000107 MGI:3055648 NCBI chr 5:143,387,981...143,578,839
Ensembl chr 5:149,506,367...149,590,930 		JBrowse link
G SPINK9 serine peptidase inhibitor Kazal type 9 acts_upstream_of_or_within ISO (MGI:3662793|PMID:16930550) MGI PMID:16930550 MGI:3662793 NCBI chr 5:143,746,900...143,766,766 JBrowse link
G TIMP2 TIMP metallopeptidase inhibitor 2 ISO RGD PMID:17532789 RGD:2290425 NCBI chr17:72,928,692...73,001,892
Ensembl chr17:78,476,807...78,495,649 		JBrowse link
G TIMP3 TIMP metallopeptidase inhibitor 3 ISO RGD PMID:17532789 RGD:2290425 NCBI chr22:13,811,297...13,872,799
Ensembl chr22:31,662,562...31,723,964 		JBrowse link
G TM4SF20 transmembrane 4 L six family member 20 involved_in ISO (PMID:25310401), (PMID:27499293) UniProt PMID:25310401 PMID:27499293 NCBI chr2B:114,606,488...114,623,569 JBrowse link
G TP53 tumor protein p53 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5468878|PMID:23277542) MGI
Ensembl		 PMID:23277542 GO_REF:0000107 MGI:5468878 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120 		JBrowse link
negative regulation of proteolysis involved in protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:25217637)
(MGI:5468878|PMID:23277542)		 ParkinsonsUK-UCL
MGI		 PMID:23277542 PMID:25217637 MGI:5468878 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,475,128...130,482,531
Ensembl chr 1:134,083,855...134,091,228 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PABPN1L PABPN1 like, cytoplasmic acts_upstream_of_or_within ISO (MGI:6509513|PMID:32558204) MGI PMID:32558204 MGI:6509513 NCBI chr16:69,579,421...69,583,803
Ensembl chr16:89,234,156...89,237,595 		JBrowse link
G STYX serine/threonine/tyrosine interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:33,326,587...33,371,399
Ensembl chr14:51,610,523...51,651,096 		JBrowse link
negative regulation of serine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CR1 complement C3b/C4b receptor 1 (Knops blood group) involved_in ISO (PMID:6910481) UniProt PMID:6910481 NCBI chr 1:183,094,601...183,246,957 JBrowse link
G SERPINA1 serpin family A member 1 ISO RGD PMID:19240864 RGD:7411612 NCBI chr14:75,001,714...75,014,214
Ensembl chr14:94,334,258...94,345,419 		JBrowse link
G SPINK1 serine peptidase inhibitor Kazal type 1 acts_upstream_of_or_within ISO (MGI:5428115|PMID:22228629)
(MGI:4442135|PMID:20110462)		 RGD
MGI		 PMID:12771515 PMID:20110462 PMID:22228629 MGI:4442135 MGI:5428115 RGD:724699 NCBI chr 5:143,273,137...143,287,745 JBrowse link
G SPINK2 serine peptidase inhibitor Kazal type 2 acts_upstream_of_or_within ISO (MGI:5287926|PMID:21705336) MGI PMID:21705336 MGI:5287926 NCBI chr 4:67,101,686...67,113,671 JBrowse link
G SPINK5 serine peptidase inhibitor Kazal type 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:143,387,981...143,578,839
Ensembl chr 5:149,506,367...149,590,930 		JBrowse link
G SPINK6 serine peptidase inhibitor Kazal type 6 acts_upstream_of_or_within ISO (MGI:5560845|PMID:24352040) MGI PMID:24352040 MGI:5560845 NCBI chr 5:143,631,560...143,644,177
Ensembl chr 5:149,639,882...149,652,448 		JBrowse link
negative regulation of serine-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPINK5 serine peptidase inhibitor Kazal type 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4440399|PMID:20179351) MGI
Ensembl		 PMID:20179351 GO_REF:0000107 MGI:4440399 NCBI chr 5:143,387,981...143,578,839
Ensembl chr 5:149,506,367...149,590,930 		JBrowse link
negative regulation of ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A acts_upstream_of_or_within ISO (MGI:4461099|PMID:20100865) MGI PMID:20100865 MGI:4461099 NCBI chr 6:34,450,695...34,653,881
Ensembl chr 6:35,548,124...35,776,185 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A involved_in
acts_upstream_of_or_within		 ISO (PMID:16173922), (PMID:18560357)
(MGI:5468878|PMID:23277542)		 UniProt
MGI		 PMID:16173922 PMID:18560357 PMID:23277542 MGI:5468878 NCBI chr 9:21,803,862...21,831,322 JBrowse link
G CSNK2A1 casein kinase 2 alpha 1 involved_in ISO (PMID:28031292) ARUK-UCL PMID:28031292 NCBI chr20:689,494...752,092
Ensembl chr20:456,629...521,126 		JBrowse link
G CSNK2A2 casein kinase 2 alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:38,426,399...38,466,575
Ensembl chr16:57,557,270...57,596,218 		JBrowse link
G HFE homeostatic iron regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 involved_in ISO (PMID:21628596) FlyBase PMID:21628596 NCBI chr 7:131,506,711...131,722,943 JBrowse link
G LOC100973105 40S ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:180,845,832...180,846,513 JBrowse link
G PDCL3 phosducin like 3 acts_upstream_of_or_within ISO (PMID:23792958) MGI PMID:23792958
G PML PML nuclear body scaffold involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:52,903,874...52,955,151
Ensembl chr15:71,658,884...71,710,883 		JBrowse link
G PRMT6 protein arginine methyltransferase 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:109,582,715...109,586,744
Ensembl chr 1:108,699,098...108,700,225 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G QRICH2 glutamine rich 2 involved_in ISO (PMID:30683861)
(MGI:6277293|PMID:30683861)		 UniProt PMID:30683861 MGI:6277293 NCBI chr17:70,222,033...70,256,747
Ensembl chr17:75,774,651...75,807,651 		JBrowse link
G RPL11 ribosomal protein L11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:22,883,157...22,887,806
Ensembl chr 1:23,868,688...23,873,313 		JBrowse link
G RPL23 ribosomal protein L23 involved_in ISO (PMID:15314173) CAFA PMID:15314173 NCBI chr17:18,417,964...18,421,708
Ensembl chr17:18,690,682...18,698,253 		JBrowse link
G RPL5 ribosomal protein L5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:95,497,047...95,507,006
Ensembl chr 1:94,230,451...94,241,522 		JBrowse link
G RPS7 ribosomal protein S7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:3,593,350...3,599,106
Ensembl chr2A:3,512,079...3,517,785 		JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4355593|PMID:19684112) MGI
Ensembl		 PMID:19684112 GO_REF:0000107 MGI:4355593 NCBI chr10:99,107,516...99,231,761
Ensembl chr10:102,571,886...102,696,472 		JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323 		JBrowse link
G TRIM39 tripartite motif containing 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,104,381...30,121,649
Ensembl chr 6:30,975,260...30,995,764 		JBrowse link
G WNT1 Wnt family member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 NCBI chr12:39,767,839...39,772,460
Ensembl chr12:40,648,413...40,652,583 		JBrowse link
negative regulation of ubiquitin-specific protease activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PARK7 Parkinsonism associated deglycase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G UBXN1 UBX domain protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:58,033,304...58,035,893
Ensembl chr11:61,386,797...61,389,404 		JBrowse link
positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:22406537) ARUK-UCL PMID:22406537 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G EFNA1 ephrin A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,475,128...130,482,531
Ensembl chr 1:134,083,855...134,091,228 		JBrowse link
G EFNA3 ephrin A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:130,426,910...130,435,628
Ensembl chr 1:134,036,490...134,045,213 		JBrowse link
G EPHA4 EPH receptor A4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:108,664,475...108,818,802
Ensembl chr2B:227,248,958...227,402,790 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G PICALM phosphatidylinositol binding clathrin assembly protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:81,011,324...81,122,352
Ensembl chr11:84,619,241...84,730,684 		JBrowse link
G ROCK2 Rho associated coiled-coil containing protein kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:11,167,353...11,331,339
Ensembl chr2A:11,318,370...11,478,986 		JBrowse link
positive regulation of aspartic-type peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GRN granulin precursor involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:13,046,329...13,054,236
Ensembl chr17:13,211,784...13,219,609 		JBrowse link
positive regulation of cysteine-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIM2 absent in melanoma 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:134,413,232...134,540,344
Ensembl chr 1:138,210,946...138,221,753 		JBrowse link
G BBC3 BCL2 binding component 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:44,203,517...44,215,860 JBrowse link
G FYN FYN proto-oncogene, Src family tyrosine kinase involved_in ISO PMID:17526495 ARUK-UCL PMID:17526495 RGD:13506268 NCBI chr 6:109,469,750...109,684,086
Ensembl chr 6:113,545,944...113,604,451 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 involved_in ISO PMID:17526495 ARUK-UCL PMID:17526495 RGD:13506268 NCBI chr 9:108,198,350...108,228,887
Ensembl chr 9:137,168,722...137,197,382 		JBrowse link
G GRIN2B glutamate ionotropic receptor NMDA type subunit 2B involved_in ISO PMID:17526495 ARUK-UCL PMID:17526495 RGD:13506268 NCBI chr12:13,543,104...13,987,437
Ensembl chr12:13,969,387...14,388,799 		JBrowse link
G MEFV MEFV innate immunity regulator, pyrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:2,175,858...2,191,056
Ensembl chr16:3,353,666...3,368,970 		JBrowse link
G NEK5 NIMA related kinase 5 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5500844|PMID:23727203) MGI
Ensembl		 PMID:23727203 GO_REF:0000107 MGI:5500844 NCBI chr13:33,166,069...33,260,990
Ensembl chr13:51,938,342...51,998,357 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G TTBK1 tau tubulin kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:42,835,285...42,880,100
Ensembl chr 6:44,131,360...44,169,912 		JBrowse link
G USP50 ubiquitin specific peptidase 50 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5888801|PMID:28094437)
(PMID:28094437)		 MGI
Ensembl		 PMID:28094437 GO_REF:0000107 MGI:5888801 NCBI chr15:29,450,804...29,500,515
Ensembl chr15:47,790,100...47,839,619 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1C activin A receptor type 1C involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO RGD PMID:15105833 RGD:2313858 NCBI chr17:7,026,839...7,041,598
Ensembl chr17:7,014,591...7,029,602 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:21803450) ARUK-UCL PMID:21803450 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G ARL6IP5 ADP ribosylation factor like GTPase 6 interacting protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:69,020,908...69,042,065
Ensembl chr 3:70,387,581...70,408,909 		JBrowse link
G ARRB1 arrestin beta 1 ISO RGD PMID:19171933 RGD:5510006 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BCAP31 B cell receptor associated protein 31 involved_in ISO (PMID:21183955) UniProt PMID:21183955 NCBI chr  X:143,265,920...143,274,956 JBrowse link
G BCL10 BCL10 immune signaling adaptor involved_in
acts_upstream_of_or_within		 ISO (PMID:22267217)
(MGI:1355482|PMID:10753917)		 ARUK-UCL
MGI		 PMID:10753917 PMID:22267217 MGI:1355482 NCBI chr 1:117,823,388...117,834,314 JBrowse link
G BCL2L11 BCL2 like 11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3581932|PMID:15967824) MGI
Ensembl		 PMID:15967824 GO_REF:0000107 MGI:3581932 NCBI chr2A:90,862,070...90,909,833
Ensembl chr2A:112,337,927...112,385,079 		JBrowse link
G BLID BH3-like motif containing, cell death inducer involved_in ISO (PMID:15069058) UniProt PMID:15069058 NCBI chr11:116,952,577...116,966,026 JBrowse link
G CARD9 caspase recruitment domain family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:107,432,709...107,446,271
Ensembl chr 9:136,416,279...136,424,756 		JBrowse link
G CASP1 caspase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:99,965,964...99,975,640
Ensembl chr11:103,448,497...103,458,149
Ensembl chr11:103,448,497...103,458,149 		JBrowse link
G CCN1 cellular communication network factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3849354|PMID:19364818) MGI
Ensembl		 PMID:19364818 GO_REF:0000107 MGI:3849354 NCBI chr 1:118,138,739...118,141,681
Ensembl chr 1:86,994,296...86,997,147 		JBrowse link
G CCN2 cellular communication network factor 2 ISO caspase 3/7 RGD PMID:19625611 RGD:2314487 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077 		JBrowse link
G CLEC7A C-type lectin domain containing 7A involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:10,161,780...10,174,943
Ensembl chr12:10,410,384...10,425,452 		JBrowse link
G CTSD cathepsin D involved_in ISO (PMID:12107093) ARUK-UCL PMID:12107093 NCBI chr11:1,789,326...1,800,524 JBrowse link
G DAPK1 death associated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:58,628,872...58,836,205
Ensembl chr 9:86,681,953...86,887,958 		JBrowse link
G DDX3X DEAD-box helicase 3 X-linked involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:33,780,381...33,796,829
Ensembl chr  X:41,475,116...41,505,837 		JBrowse link
G F2R coagulation factor II thrombin receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,565,957...38,585,725
Ensembl chr 5:39,110,170...39,129,688 		JBrowse link
G FAS Fas cell surface death receptor ISO RGD PMID:15519734 RGD:8662904 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G FIS1 fission, mitochondrial 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:93,381,058...93,386,483
Ensembl chr 7:106,621,211...106,626,683 		JBrowse link
G FOXL2 forkhead box L2 involved_in ISO (PMID:16153597) UniProt PMID:16153597 NCBI chr 3:135,968,040...135,980,063 JBrowse link
G GRAMD4 GRAM domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:26,789,989...26,877,172
Ensembl chr22:45,687,833...45,745,518 		JBrowse link
G HMGB1 high mobility group box 1 involved_in ISO (PMID:19800306) UniProt PMID:19800306 NCBI chr13:11,737,942...11,894,923
Ensembl chr13:30,174,899...30,179,527 		JBrowse link
G HSF1 heat shock transcription factor 1 ISO RGD PMID:21192280 RGD:10403035 NCBI chr 8:141,055,310...141,078,360
Ensembl chr 8:144,062,137...144,067,866 		JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152 		JBrowse link
G IL24 interleukin 24 acts_upstream_of_or_within ISO (MGI:3821693|PMID:18708357) MGI PMID:18708357 MGI:3821693 NCBI chr 1:182,500,680...182,507,098
Ensembl chr 1:186,779,207...186,785,928 		JBrowse link
G LOC100967334 G-protein coupled estrogen receptor 1 involved_in ISO PMID:23907461 UniProt PMID:23907461 RGD:8553942 NCBI chr 7:1,245,873...1,251,915 JBrowse link
G LOC100969375 caspase recruitment domain-containing protein 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:45,204,735...45,256,481
Ensembl chr19:53,798,967...53,850,328 		JBrowse link
G LOC100976022 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:153,137,992...153,161,628 JBrowse link
G MALT1 MALT1 paracaspase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,060,878...52,141,985
Ensembl chr18:55,395,462...55,473,574 		JBrowse link
G MAP3K5 mitogen-activated protein kinase kinase kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:134,316,841...134,582,843
Ensembl chr 6:138,406,398...138,641,727 		JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:14522843 RGD:2304239 NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135 		JBrowse link
G MEN1 menin 1 acts_upstream_of_or_within ISO (MGI:3037372|PMID:14688275) MGI PMID:14688275 MGI:3037372 NCBI chr11:60,159,009...60,166,222
Ensembl chr11:63,499,962...63,507,164 		JBrowse link
G MTCH2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (MGI:5662300|PMID:26219591) MGI PMID:26219591 MGI:5662300 NCBI chr11:47,566,884...47,596,711
Ensembl chr11:48,115,774...48,146,312 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:124,387,561...124,393,551
Ensembl chr 8:127,131,512...127,136,863 		JBrowse link
G NDUFA13 NADH:ubiquinone oxidoreductase subunit A13 involved_in ISO (PMID:17297443) ParkinsonsUK-UCL PMID:17297443 NCBI chr19:18,954,214...18,966,634 JBrowse link
G NKX3-1 NK3 homeobox 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:22,926,145...22,930,396
Ensembl chr 8:19,863,275...19,864,942 		JBrowse link
G NLRP2 NLR family pyrin domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,006,026...52,038,766
Ensembl chr19:60,700,166...60,732,329 		JBrowse link
G NLRP3 NLR family pyrin domain containing 3 involved_in ISO (PMID:15030775) HGNC-UCL PMID:15030775 NCBI chr 1:223,052,307...223,084,736
Ensembl chr 1:228,505,147...228,537,216 		JBrowse link
G NOD1 nucleotide binding oligomerization domain containing 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10329646) MGI
Ensembl		 PMID:10329646 GO_REF:0000107 NCBI chr 7:31,060,245...31,109,012
Ensembl chr 7:31,182,275...31,208,742 		JBrowse link
G NODAL nodal growth differentiation factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:66,906,866...66,916,938
Ensembl chr10:69,433,959...69,443,972 		JBrowse link
G PDCD5 programmed cell death 5 involved_in ISO (PMID:16374546) UniProt PMID:16374546 NCBI chr19:29,500,983...29,507,277
Ensembl chr19:38,248,576...38,254,909 		JBrowse link
G PDCD6 programmed cell death 6 involved_in ISO (PMID:16132846) UniProt PMID:16132846 NCBI chr 5:250,025...291,055 JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:14699081) UniProt PMID:14699081 NCBI chr18:53,286,590...53,290,913
Ensembl chr18:56,611,098...56,615,449 		JBrowse link
G PPM1F protein phosphatase, Mg2+/Mn2+ dependent 1F involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:4,039,032...4,072,165
Ensembl chr22:20,520,022...20,553,128 		JBrowse link
G PPP2CA protein phosphatase 2 catalytic subunit alpha ISO RGD PMID:18322138 RGD:8693423 NCBI chr 5:129,599,606...129,629,312
Ensembl chr 5:135,751,958...135,765,786 		JBrowse link
G PYCARD PYD and CARD domain containing involved_in ISO
IEA		 RGD
Ensembl		 PMID:19401709 GO_REF:0000107 RGD:5491174 NCBI chr16:23,764,386...23,765,732
Ensembl chr16:31,571,363...31,573,828 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
G RHOA ras homolog family member A ISO RGD PMID:17425560 RGD:1642961 NCBI chr 3:49,282,009...49,339,887 JBrowse link
G SIRT1 sirtuin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G SOX7 SRY-box transcription factor 7 involved_in ISO (PMID:19108950) UniProt PMID:19108950 NCBI chr 8:8,476,357...8,483,144 JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TNFSF10 TNF superfamily member 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:169,512,491...169,530,706
Ensembl chr 3:177,694,021...177,712,137 		JBrowse link
G UACA uveal autoantigen with coiled-coil domains and ankyrin repeats acts_upstream_of_or_within ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chr15:49,607,308...49,711,188
Ensembl chr15:68,375,939...68,477,395 		JBrowse link
G WDR35 WD repeat domain 35 ISO RGD PMID:20193664 RGD:11553917 NCBI chr2A:19,896,498...19,977,295
Ensembl chr2A:20,014,127...20,093,810 		JBrowse link
G WNT3A Wnt family member 3A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3702339|PMID:17251350) MGI
Ensembl		 PMID:17251350 GO_REF:0000107 MGI:3702339 NCBI chr 1:203,409,294...203,463,214
Ensembl chr 1:208,628,706...208,674,469 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FAS Fas cell surface death receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:85,707,457...85,741,539
Ensembl chr10:89,217,949...89,243,612 		JBrowse link
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831 		JBrowse link
G HTRA2 HtrA serine peptidase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:74,596,020...74,599,790
Ensembl chr2A:76,102,240...76,106,152 		JBrowse link
G LGALS9 galectin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G LOC100975471 suppression of tumorigenicity 18 protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:48,528,831...48,832,588
Ensembl chr 8:45,913,225...46,016,468 		JBrowse link
G PRR7 proline rich 7, synaptic involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,748,020...172,757,989
Ensembl chr 5:179,818,184...179,821,479 		JBrowse link
G TFAP4 transcription factor AP-4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4456943|PMID:15944155) MGI
Ensembl		 PMID:15944155 GO_REF:0000107 MGI:4456943 NCBI chr16:3,176,129...3,226,404
Ensembl chr16:4,348,929...4,368,525 		JBrowse link
positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RFPL1 ret finger protein like 1 involved_in ISO (PMID:20725088) UniProt PMID:20725088 NCBI chr22:10,485,218...10,488,052 JBrowse link
G RPS3 ribosomal protein S3 involved_in ISO (PMID:22510408) UniProt PMID:22510408 NCBI chr11:70,460,702...70,466,909
Ensembl chr11:73,762,794...73,768,982 		JBrowse link
G TNF tumor necrosis factor ISO RGD PMID:12131680 RGD:14995454 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
positive regulation of endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKIRIN2 akirin 2 ISO MMP-9 RGD PMID:18460465 RGD:2306009 NCBI chr 6:85,549,728...85,577,114 JBrowse link
G APH1A aph-1 homolog A, gamma-secretase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:125,610,649...125,614,261
Ensembl chr 1:129,262,002...129,265,810 		JBrowse link
G APH1B aph-1 homolog B, gamma-secretase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:42,224,593...42,256,202
Ensembl chr15:60,520,031...60,551,599 		JBrowse link
G NCSTN nicastrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911 		JBrowse link
G PRELID1 PRELI domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,605,767...172,608,901
Ensembl chr 5:179,669,885...179,672,965 		JBrowse link
G PSENEN presenilin enhancer, gamma-secretase subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,675,331...32,677,285
Ensembl chr19:41,409,662...41,411,089 		JBrowse link
G SFRP2 secreted frizzled related protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3839034|PMID:19079247) MGI
Ensembl		 PMID:19079247 GO_REF:0000107 MGI:3839034 NCBI chr 4:146,123,075...146,131,543
Ensembl chr 4:157,944,733...157,953,258 		JBrowse link
G VSIR V-set immunoregulatory receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:68,218,230...68,243,687
Ensembl chr10:70,742,062...70,767,613 		JBrowse link
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCAP31 B cell receptor associated protein 31 involved_in ISO (PMID:18555783) ParkinsonsUK-UCL PMID:18555783 NCBI chr  X:143,265,920...143,274,956 JBrowse link
G CAV1 caveolin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:108,497,125...108,533,090
Ensembl chr 7:121,193,424...121,229,655 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:37,210,170...37,221,961
Ensembl chr16:56,343,025...56,355,164 		JBrowse link
G LOC100976022 B cell receptor associated protein 31 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr  X:153,137,992...153,161,628 JBrowse link
G SGTA small glutamine rich tetratricopeptide repeat co-chaperone alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:1,778,728...1,808,199
Ensembl chr19:2,736,565...2,763,440 		JBrowse link
G UBQLN1 ubiquilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:41,170,416...41,218,656
Ensembl chr 9:82,597,507...82,645,587 		JBrowse link
G UBQLN2 ubiquilin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:48,829,844...48,835,040
Ensembl chr  X:56,981,985...56,983,859 		JBrowse link
positive regulation of ERAD pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATXN3 ataxin 3 involved_in ISO (PMID:17000876) ParkinsonsUK-UCL PMID:17000876 NCBI chr14:72,693,446...72,741,772 JBrowse link
G BAG6 BAG cochaperone 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321 		JBrowse link
G RNF185 ring finger protein 185 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:12,183,591...12,230,371
Ensembl chr22:30,020,353...30,066,266 		JBrowse link
G RNFT1 ring finger protein, transmembrane 1 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr17:54,016,689...54,029,100
Ensembl chr17:58,858,416...58,869,908 		JBrowse link
G RNFT2 ring finger protein, transmembrane 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr12:114,315,117...114,430,273
Ensembl chr12:117,691,632...117,804,833 		JBrowse link
G TMEM67 transmembrane protein 67 ISO RGD PMID:19815549 RGD:8554391 NCBI chr 8:90,378,623...90,442,904
Ensembl chr 8:92,324,402...92,387,437 		JBrowse link
G USP13 ubiquitin specific peptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:176,685,541...176,818,360
Ensembl chr 3:184,855,388...184,983,158 		JBrowse link
G WFS1 wolframin ER transmembrane glycoprotein involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 4:6,345,864...6,379,287 JBrowse link
positive regulation of histone deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SART3 spliceosome associated factor 3, U4/U6 recycling protein involved_in ISO (PMID:24526689) UniProt PMID:24526689 NCBI chr12:106,093,738...106,132,710
Ensembl chr12:109,489,932...109,529,091 		JBrowse link
positive regulation of Lys63-specific deubiquitinase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
positive regulation of membrane protein ectodomain proteolysis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAM8 ADAM metallopeptidase domain 8 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr10:134,172,724...134,186,227 JBrowse link
G ADAM9 ADAM metallopeptidase domain 9 involved_in ISO (MGI:1326990|PMID:9857183) BHF-UCL PMID:9857183 MGI:1326990 NCBI chr 8:38,298,194...38,406,706
Ensembl chr 8:35,473,278...35,581,192 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:17655843) BHF-UCL PMID:17655843 NCBI chr10:107,669,860...107,673,685 JBrowse link
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
G APP amyloid beta precursor protein involved_in ISO (PMID:25015123) ARUK-UCL PMID:25015123 NCBI chr21:12,324,455...12,608,594
Ensembl chr21:25,684,355...25,995,072 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G NRDC nardilysin convertase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:51,038,711...51,130,404
Ensembl chr 1:52,535,603...52,625,998 		JBrowse link
G PACSIN3 protein kinase C and casein kinase substrate in neurons 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:47,122,620...47,131,559
Ensembl chr11:47,676,432...47,684,485 		JBrowse link
G RGMA repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5702499|PMID:26651291) MGI
Ensembl		 PMID:26651291 GO_REF:0000107 MGI:5702499 NCBI chr15:71,728,669...71,774,447
Ensembl chr15:90,922,199...90,956,179 		JBrowse link
G SH3D19 SH3 domain containing 19 involved_in ISO (PMID:15280379) BHF-UCL PMID:15280379 NCBI chr 4:143,460,618...143,664,796
Ensembl chr 4:155,115,280...155,217,392 		JBrowse link
G SNX33 sorting nexin 33 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:54,556,304...54,570,683
Ensembl chr15:74,151,053...74,159,584 		JBrowse link
G SNX9 sorting nexin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:155,724,026...155,844,553
Ensembl chr 6:157,824,918...157,903,357 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:10,915,743...10,957,765
Ensembl chr 1:12,130,663...12,172,646 		JBrowse link
positive regulation of metalloendopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 involved_in ISO (PMID:23389627) AgBase PMID:23389627 NCBI chr 1:131,282,514...131,326,535
Ensembl chr 1:135,112,040...135,159,299 		JBrowse link
G MBP myelin basic protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:70,369,882...70,526,693
Ensembl chr18:73,629,522...73,755,351 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067 		JBrowse link
positive regulation of metallopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTXR1 ANTXR cell adhesion molecule 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5662198|PMID:25572963) MGI
Ensembl		 PMID:25572963 GO_REF:0000107 MGI:5662198 NCBI chr2A:69,054,253...69,290,554
Ensembl chr2A:70,175,982...70,412,454 		JBrowse link
G CLDN3 claudin 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:80,924,731...80,925,393 JBrowse link
G CLDN4 claudin 4 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:80,983,832...80,984,461 JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
positive regulation of peptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSH cathepsin H involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:57,893,379...57,917,194
Ensembl chr15:76,852,668...76,876,976 		JBrowse link
G PRSS22 serine protease 22 involved_in ISO (PMID:15701722) UniProt PMID:15701722 NCBI chr16:1,790,787...1,797,025 JBrowse link
G RCN3 reticulocalbin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:46,540,352...46,556,508
Ensembl chr19:55,463,535...55,477,478 		JBrowse link
positive regulation of plasminogen activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250 		JBrowse link
G CLEC3B C-type lectin domain family 3 member B involved_in ISO (MGI:5447625|PMID:12694198) UniProt PMID:12694198 MGI:5447625 NCBI chr 3:44,927,098...44,936,847
Ensembl chr 3:46,038,115...46,047,927 		JBrowse link
G ENO1 enolase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:7,619,490...7,637,558
Ensembl chr 1:8,855,074...8,873,215 		JBrowse link
G F12 coagulation factor XII involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,703,724...172,711,618
Ensembl chr 5:179,766,243...179,773,485 		JBrowse link
G HPN hepsin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,985,761...32,012,841
Ensembl chr19:40,725,319...40,750,628 		JBrowse link
G MELTF melanotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,345,474...194,373,690
Ensembl chr 3:204,262,182...204,310,710 		JBrowse link
G PLGRKT plasminogen receptor with a C-terminal lysine acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4437195|PMID:19897580) MGI
Ensembl
InterPro		 PMID:19897580 GO_REF:0000002 GO_REF:0000107 MGI:4437195 NCBI chr 9:5,196,843...5,257,138
Ensembl chr 9:5,382,302...5,441,993 		JBrowse link
G RUVBL1 RuvB like AAA ATPase 1 ISO RGD PMID:11027681 RGD:67924 NCBI chr 3:125,120,524...125,200,859
Ensembl chr 3:132,486,229...132,528,918 		JBrowse link
G S100A10 S100 calcium binding protein A10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:127,341,974...127,353,054
Ensembl chr 1:130,985,312...130,995,130 		JBrowse link
positive regulation of proteasomal protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,730,297...56,743,123
Ensembl chr 6:58,360,889...58,373,733 		JBrowse link
G DAB2IP DAB2 interacting protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:92,696,798...92,912,425
Ensembl chr 9:121,143,457...121,254,336 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G ECSCR endothelial cell surface expressed chemotaxis and apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:19416853) MGI
Ensembl		 PMID:19416853 GO_REF:0000107 NCBI chr 5:134,819,568...134,833,508
Ensembl chr 5:140,940,578...140,955,140 		JBrowse link
G FBXW7 F-box and WD repeat domain containing 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:144,660,676...144,874,404
Ensembl chr 4:156,312,274...156,402,351 		JBrowse link
G FMR1 Fragile X messenger ribonucleoprotein 1 involved_in ISO (MGI:5770038|PMID:24709664) UniProt PMID:24709664 MGI:5770038 NCBI chr  X:136,937,889...136,976,828
Ensembl chr  X:147,365,748...147,405,321 		JBrowse link
G KCNE2 potassium voltage-gated channel subfamily E regulatory subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:20,548,631...20,739,999
Ensembl chr21:34,107,443...34,107,814
Ensembl chr21:34,107,443...34,107,814 		JBrowse link
G NUPR1 nuclear protein 1, transcriptional regulator involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:29,015,155...29,016,987 JBrowse link
G OSBPL7 oxysterol binding protein like 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:9,715,464...9,729,950
Ensembl chr17:9,897,768...9,912,065 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G PSMC1 proteasome 26S subunit, ATPase 1 involved_in IEA GOC GO_REF:0000108 NCBI chr14:70,873,846...70,889,988
Ensembl chr14:90,225,405...90,241,641 		JBrowse link
G PSMC2 proteasome 26S subunit, ATPase 2 involved_in IEA GOC GO_REF:0000108 NCBI chr 7:95,338,743...95,359,353
Ensembl chr 7:108,083,203...108,103,494 		JBrowse link
G PSMC3 proteasome 26S subunit, ATPase 3 involved_in IEA GOC GO_REF:0000108 NCBI chr11:47,366,986...47,374,677
Ensembl chr11:47,920,295...47,927,654 		JBrowse link
G PSMC4 proteasome 26S subunit, ATPase 4 involved_in IEA GOC GO_REF:0000108 NCBI chr19:37,018,112...37,028,490
Ensembl chr19:45,533,141...45,543,245 		JBrowse link
G PSMC5 proteasome 26S subunit, ATPase 5 involved_in IEA GOC GO_REF:0000108 NCBI chr17:57,906,934...57,911,551
Ensembl chr17:63,051,050...63,055,907 		JBrowse link
G PSMC6 proteasome 26S subunit, ATPase 6 involved_in IEA GOC GO_REF:0000108 NCBI chr14:33,303,689...33,324,502
Ensembl chr14:51,587,467...51,608,044 		JBrowse link
G RNF40 ring finger protein 40 ISO RGD PMID:12121982 RGD:633892 NCBI chr16:24,194,293...24,207,460
Ensembl chr16:31,129,352...31,142,280 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:85,683,455...85,741,118
Ensembl chr12:88,989,033...89,046,630 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
G XBP1 X-box binding protein 1 acts_upstream_of_or_within ISO (MGI:4946566|PMID:21317886) MGI PMID:21317886 MGI:4946566 NCBI chr22:9,863,479...9,869,491
Ensembl chr22:27,567,041...27,571,943 		JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3589701|PMID:15937334) MGI
Ensembl		 PMID:15937334 GO_REF:0000107 MGI:3589701 NCBI chr14:85,417,229...85,444,722
Ensembl chr14:105,208,128...105,236,756 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (MGI:5465208|PMID:23152632) MGI PMID:23152632 MGI:5465208 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398 		JBrowse link
G AURKA aurora kinase A acts_upstream_of_or_within ISO (MGI:3697244|PMID:17060449) MGI PMID:17060449 MGI:3697244 NCBI chr20:52,707,757...52,730,579
Ensembl chr20:53,994,881...54,017,339 		JBrowse link
G AXIN1 axin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3628833|PMID:16601693) MGI
Ensembl		 PMID:16601693 GO_REF:0000107 MGI:3628833 Ensembl chr16:278,239...337,891 JBrowse link
G BAG2 BAG cochaperone 2 NOT|involved_in ISO (MGI:6148635|PMID:19228967) ARUK-UCL PMID:19228967 MGI:6148635 NCBI chr 6:56,730,297...56,743,123
Ensembl chr 6:58,360,889...58,373,733 		JBrowse link
G BBS7 Bardet-Biedl syndrome 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:22302990) MGI
Ensembl		 PMID:22302990 GO_REF:0000107 NCBI chr 4:114,024,949...114,072,000
Ensembl chr 4:125,161,804...125,208,350 		JBrowse link
G CBFA2T3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:69,592,293...69,662,321
Ensembl chr16:89,246,545...89,347,435 		JBrowse link
G CLU clusterin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:26,867,973...26,884,838
Ensembl chr 8:24,070,053...24,083,523 		JBrowse link
G COP1 COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:151,459,354...151,727,131
Ensembl chr 1:155,156,185...155,425,156 		JBrowse link
G CSNK1A1 casein kinase 1 alpha 1 involved_in ISO (PMID:11955436)
(PMID:19364825)		 ParkinsonsUK-UCL
FlyBase		 PMID:11955436 PMID:19364825 NCBI chr 5:144,919,775...144,977,105
Ensembl chr 5:150,929,420...150,985,912 		JBrowse link
G CSNK1D casein kinase 1 delta involved_in ISO (MGI:3849793|PMID:19414593) UniProt PMID:19414593 MGI:3849793 NCBI chr17:76,648,677...76,683,054
Ensembl chr17:82,462,467...82,494,348 		JBrowse link
G CSNK1E casein kinase 1 epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:19,202,599...19,229,344
Ensembl chr22:37,027,094...37,072,942 		JBrowse link
G DAB2 DAB adaptor protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443 		JBrowse link
G DDRGK1 DDRGK domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G DET1 DET1 partner of COP1 E3 ubiquitin ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:67,203,101...67,238,185
Ensembl chr15:86,411,937...86,444,789 		JBrowse link
G DNAJB2 DnaJ heat shock protein family (Hsp40) member B2 involved_in ISO (PMID:15936278) BHF-UCL PMID:15936278 NCBI chr2B:106,536,846...106,544,430
Ensembl chr2B:225,127,967...225,135,556 		JBrowse link
G DVL1 dishevelled segment polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008 		JBrowse link
G FBXO22 F-box protein 22 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) MGI PMID:19319192 MGI:3840749 NCBI chr15:54,817,076...54,849,271
Ensembl chr15:74,410,213...74,441,609 		JBrowse link
G GABARAP GABA type A receptor-associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:7,270,316...7,272,365
Ensembl chr17:7,257,659...7,260,276 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3695876|PMID:17189825) MGI
Ensembl		 PMID:17189825 GO_REF:0000107 MGI:3695876 NCBI chr 6:53,052,145...53,102,794
Ensembl chr 6:54,687,315...54,734,994 		JBrowse link
G GSK3A glycogen synthase kinase 3 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:39,118,330...39,130,768
Ensembl chr19:47,710,197...47,726,948 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5437589|PMID:22660580) MGI
Ensembl		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 3:116,943,205...117,215,001
Ensembl chr 3:123,861,379...124,126,771 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:24613385) UniProt PMID:24613385 NCBI chr 6:31,476,710...31,491,411 JBrowse link
G HSPBP1 HSPA (Hsp70) binding protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:52,303,121...52,322,771
Ensembl chr19:60,995,202...61,013,756 		JBrowse link
G IL33 interleukin 33 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5437589|PMID:22660580) MGI
Ensembl		 PMID:22660580 GO_REF:0000107 MGI:5437589 NCBI chr 9:6,027,014...6,069,540
Ensembl chr 9:6,234,178...6,248,624 		JBrowse link
G KLHL40 kelch like family member 40 involved_in ISO (MGI:5700633|PMID:25940086) UniProt PMID:25940086 MGI:5700633 NCBI chr 3:42,592,977...42,600,100
Ensembl chr 3:43,657,128...43,664,055 		JBrowse link
G LOC100974874 E3 ubiquitin-protein ligase CHFR acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5310666|PMID:22285184) MGI
Ensembl		 PMID:22285184 GO_REF:0000107 MGI:5310666 NCBI chr12:130,201,704...130,247,891
Ensembl chr12:134,923,458...134,968,832 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:48,343,621...48,488,337
Ensembl chr12:49,205,930...49,350,462 		JBrowse link
G MDM2 MDM2 proto-oncogene involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:66,322,340...66,357,010
Ensembl chr12:69,102,084...69,133,278 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:1,285,217...1,311,285
Ensembl chr 5:1,075,172...1,081,664 		JBrowse link
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:25818168), (PMID:27323397)
(MGI:5897550|PMID:21804542)		 UniProt PMID:21804542 PMID:25818168 PMID:27323397 MGI:5897550 NCBI chr19:44,739,739...44,751,303 JBrowse link
G NUB1 negative regulator of ubiquitin like proteins 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:142,927,730...142,964,475
Ensembl chr 7:155,079,243...155,114,676 		JBrowse link
G PABIR1 PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:56,007,323...56,011,655
Ensembl chr 9:67,544,489...67,545,352 		JBrowse link
G PIAS1 protein inhibitor of activated STAT 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:47,006,718...47,141,035
Ensembl chr15:65,276,530...65,410,105 		JBrowse link
G PLK1 polo like kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:14,420,972...14,432,821
Ensembl chr16:23,928,773...23,940,779 		JBrowse link
G PLK2 polo like kinase 2 ISO RGD PMID:18723513 RGD:7241135 NCBI chr 5:55,543,828...55,550,116
Ensembl chr 5:57,177,836...57,184,793 		JBrowse link
G PRICKLE1 prickle planar cell polarity protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:46,127,673...46,262,333
Ensembl chr12:47,100,393...47,126,102 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G PSEN1 presenilin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G PSEN2 presenilin 2 involved_in ISO (MGI:4887523|PMID:20208556) BHF-UCL PMID:20208556 MGI:4887523 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G PSMD10 proteasome 26S subunit, non-ATPase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:97,182,090...97,189,523
Ensembl chr  X:107,552,186...107,559,616 		JBrowse link
G RACK1 receptor for activated C kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:176,462,991...176,470,153
Ensembl chr 5:183,712,665...183,720,128 		JBrowse link
G RAD23A RAD23 homolog A, nucleotide excision repair protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:12,508,232...12,516,068
Ensembl chr19:13,250,718...13,258,482 		JBrowse link
G RBX1 ring-box 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:21,845,351...21,866,627
Ensembl chr22:39,941,405...39,962,175 		JBrowse link
G RCHY1 ring finger and CHY zinc finger domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:48,691,213...48,725,979
Ensembl chr 4:54,526,202...54,561,048 		JBrowse link
G RFPL1 ret finger protein like 1 involved_in ISO (PMID:20725088) UniProt PMID:20725088 NCBI chr22:10,485,218...10,488,052 JBrowse link
G RNF180 ring finger protein 180 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3819024|PMID:18363970), (MGI:5505713|PMID:23926250) MGI
Ensembl		 PMID:18363970 PMID:23926250 GO_REF:0000107 MGI:3819024 MGI:5505713 NCBI chr 5:49,624,452...49,841,741
Ensembl chr 5:51,280,064...51,454,750 		JBrowse link
G SH3RF2 SH3 domain containing ring finger 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:141,386,060...141,530,993
Ensembl chr 5:147,401,188...147,545,703 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799 		JBrowse link
G SMAD7 SMAD family member 7 involved_in ISO (PMID:11278251) BHF-UCL PMID:11278251 NCBI chr18:42,306,324...42,337,214 JBrowse link
G SOCS4 suppressor of cytokine signaling 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:35,614,238...35,636,531
Ensembl chr14:53,904,783...53,906,105 		JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr2A:46,813,589...46,878,102
Ensembl chr2A:47,804,431...47,806,041 		JBrowse link
G STUB1 STIP1 homology and U-box containing protein 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:694,414...696,682 JBrowse link
G SUMO1 small ubiquitin like modifier 1 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr2B:89,461,773...89,493,879
Ensembl chr2B:207,613,654...207,645,590 		JBrowse link
G SUMO2 small ubiquitin like modifier 2 involved_in ISO (PMID:18408734) UniProt PMID:18408734 NCBI chr17:69,115,433...69,130,065 JBrowse link
G TAF1 TATA-box binding protein associated factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:60,630,137...60,729,904
Ensembl chr  X:70,684,217...70,782,323 		JBrowse link
G TRIB1 tribbles pseudokinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:122,115,194...122,123,319
Ensembl chr 8:124,867,359...124,872,924 		JBrowse link
G TRIB2 tribbles pseudokinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:12,705,043...12,730,932
Ensembl chr2A:12,847,631...12,873,499 		JBrowse link
G UBE2V2 ubiquitin conjugating enzyme E2 V2 ISO RGD PMID:12750002 RGD:1299567 NCBI chr 8:44,435,496...44,488,517
Ensembl chr 8:41,856,429...41,878,320 		JBrowse link
G USP5 ubiquitin specific peptidase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:6,983,941...6,998,469
Ensembl chr12:6,895,416...6,909,936 		JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
G ZER1 zyg-11 related cell cycle regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:99,853,433...99,895,399
Ensembl chr 9:128,519,972...128,560,098 		JBrowse link
G ZFAND2A zinc finger AN1-type containing 2A acts_upstream_of_or_within ISO (MGI:3663213|PMID:16973439) MGI PMID:16973439 MGI:3663213 NCBI chr 7:1,392,979...1,401,283
Ensembl chr 7:1,518,912...1,526,107 		JBrowse link
G ZYG11B zyg-11 family member B, cell cycle regulator involved_in ISO (PMID:31273098) UniProt PMID:31273098 NCBI chr 1:51,987,678...52,087,093 JBrowse link
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PLK3 polo like kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:44,104,564...44,110,162
Ensembl chr 1:45,470,016...45,476,021 		JBrowse link
G SIRT2 sirtuin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:35,984,453...36,005,582
Ensembl chr19:44,533,965...44,554,799 		JBrowse link
positive regulation of protein deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TANK TRAF family member associated NFKB activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:48,426,036...48,525,265
Ensembl chr2B:165,820,833...165,896,438 		JBrowse link
G TNIP1 TNFAIP3 interacting protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:146,457,347...146,514,515
Ensembl chr 5:152,459,868...152,510,540 		JBrowse link
G WDR48 WD repeat domain 48 involved_in ISO (PMID:31253762) UniProt PMID:31253762 NCBI chr 3:38,948,440...38,992,872
Ensembl chr 3:39,228,920...39,273,300 		JBrowse link
G ZC3H12A zinc finger CCCH-type containing 12A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:36,743,341...36,753,261
Ensembl chr 1:38,093,917...38,103,556 		JBrowse link
positive regulation of protein K63-linked deubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NOP53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:27824081) UniProt PMID:27824081 NCBI chr19:44,739,739...44,751,303 JBrowse link
G VCP valosin containing protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:34,907,147...34,923,227
Ensembl chr 9:35,712,937...35,729,588 		JBrowse link
positive regulation of protein processing term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANGPTL8 angiopoietin like 8 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23150577) MGI
Ensembl		 PMID:23150577 GO_REF:0000107 NCBI chr19:10,787,457...10,790,090
Ensembl chr19:11,498,069...11,500,400 		JBrowse link
G ASTL astacin like metalloendopeptidase involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:103,176,662...103,192,542
Ensembl chr2A:97,049,184...97,063,747 		JBrowse link
G BAG2 BAG cochaperone 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,730,297...56,743,123
Ensembl chr 6:58,360,889...58,373,733 		JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:52,819,591...53,087,772
Ensembl chr18:56,149,036...56,412,222 		JBrowse link
G CNTN2 contactin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3835738|PMID:18278038) MGI
Ensembl		 PMID:18278038 GO_REF:0000107 MGI:3835738 NCBI chr 1:180,645,259...180,680,081
Ensembl chr 1:184,931,497...184,966,482 		JBrowse link
G CTNND1 catenin delta 1 acts_upstream_of_or_within ISO (MGI:3763814|PMID:17344476) MGI PMID:17344476 MGI:3763814 NCBI chr11:53,000,582...53,058,054
Ensembl chr11:56,470,174...56,527,593 		JBrowse link
G FUZ fuzzy planar cell polarity protein acts_upstream_of_or_within ISO (MGI:4367921|PMID:19877275) MGI PMID:19877275 MGI:4367921 NCBI chr19:46,819,833...46,826,235
Ensembl chr19:55,736,325...55,742,589 		JBrowse link
G MBL2 mannose binding lectin 2 ISO Masp2 RGD PMID:20118239 RGD:7242176 NCBI chr10:49,401,364...49,409,328
Ensembl chr10:51,527,758...51,543,432 		JBrowse link
G MMP14 matrix metallopeptidase 14 ISO RGD PMID:14668206 RGD:1582606 NCBI chr14:3,654,125...3,665,158
Ensembl chr14:21,753,305...21,764,058 		JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:1,285,217...1,311,285
Ensembl chr 5:1,075,172...1,081,664 		JBrowse link
G NLRC4 NLR family CARD domain containing 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:32,241,782...32,284,041
Ensembl chr2A:32,954,185...32,996,465 		JBrowse link
G RHBDD1 rhomboid domain containing 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:114,041,381...114,245,220
Ensembl chr2B:232,897,487...233,057,578 		JBrowse link
G SPON1 spondin 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3607023|PMID:16227578) MGI
Ensembl		 PMID:16227578 GO_REF:0000107 MGI:3607023 NCBI chr11:14,063,166...14,368,180
Ensembl chr11:13,776,671...14,057,741 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3763814|PMID:17344476) MGI
Ensembl		 PMID:17344476 GO_REF:0000107 MGI:3763814 NCBI chr20:33,667,614...33,727,126
Ensembl chr20:34,822,271...34,839,634 		JBrowse link
G TIMM17A translocase of inner mitochondrial membrane 17A ISO RGD PMID:9756630 RGD:13463485