Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap)  (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:pancreatic juice secretion
go back to main search page
Accession:GO:0030157 term browser browse the term
Definition:The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.


show annotations for term's descendants           Sort by:
pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:12801959) RGD PMID:12801959 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Aqp5 aquaporin 5 involved_in ISO (PMID:12801959) RGD PMID:12801959 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209 		JBrowse link
G Cel carboxyl ester lipase involved_in IEA
IBA
ISO		 GO_REF:0000107
PMID:21873635
(PMID:1854805)		 Ensembl
RGD		 PMID:1854805 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035 		JBrowse link
G Copa COPI coat complex subunit alpha acts_upstream_of_or_within ISO (PMID:1429581) RGD PMID:1429581 NCBI chr13:84,546,483...84,586,879
Ensembl chr13:84,545,943...84,586,874 		JBrowse link
negative regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Madd MAP-kinase activating death domain IMP RGD PMID:23702376 RGD:9588639 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3822255|PMID:18806227)		 Ensembl
RGD		 PMID:18806227 GO_REF:0000107 MGI:3822255 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
positive regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vamp8 vesicle-associated membrane protein 8 acts_upstream_of_or_within ISO MGI:3056083 (MGI:3801544|PMID:18535671) RGD PMID:18535671 MGI:3801544 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897 		JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (MGI:3822255|PMID:18806227) RGD PMID:18806227 MGI:3822255 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377 		JBrowse link
G Sct secretin involved_in IDA
IBA		 PMID:21873635 RGD
GO_Central		 PMID:11123201 PMID:21873635 RGD:9590235, RGD:13792537 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IDA RGD PMID:2755938 RGD:10044250 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
positive regulation of pancreatic trypsinogen secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:12771515 RGD:724699 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    multicellular organismal process 9179
      secretion by tissue 55
        pancreatic juice secretion 15
          negative regulation of pancreatic juice secretion 5
          pancreatic amylase secretion + 2
          pancreatic trypsinogen secretion + 1
          positive regulation of pancreatic juice secretion 3
          regulation of pancreatic juice secretion + 8
Path 2
Term Annotations click to browse term
  biological_process 19738
    localization 5603
      establishment of localization 4943
        transport 4771
          secretion 1182
            body fluid secretion 152
              pancreatic juice secretion 15
                negative regulation of pancreatic juice secretion 5
                pancreatic amylase secretion + 2
                pancreatic trypsinogen secretion + 1
                positive regulation of pancreatic juice secretion 3
                regulation of pancreatic juice secretion + 8
paths to the root