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ONTOLOGY REPORT - ANNOTATIONS


Term:pancreatic juice secretion
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Accession:GO:0030157 term browser browse the term
Definition:The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.



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pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp1 aquaporin 1 involved_in ISO (PMID:12801959) RGD PMID:12801959 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Aqp5 aquaporin 5 involved_in ISO (PMID:12801959) RGD PMID:12801959 NCBI chr 7:130,722,675...130,726,207
Ensembl chr 7:130,721,748...130,726,209
JBrowse link
G Cckar cholecystokinin A receptor IMP RGD PMID:16327284 RGD:2313374 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Cel carboxyl ester lipase involved_in ISO
IEA
(PMID:1854805)
GO_REF:0000107
RGD
Ensembl
PMID:1854805 GO_REF:0000107 NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
JBrowse link
G Copa COPI coat complex subunit alpha acts_upstream_of_or_within ISO (PMID:1429581) RGD PMID:1429581 NCBI chr13:84,546,483...84,586,879
Ensembl chr13:84,545,943...84,586,874
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein IEP RGD PMID:10675361 RGD:2316282 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Npr3 natriuretic peptide receptor 3 IMP RGD PMID:12829435 RGD:1581460 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Ucn urocortin IDA RGD PMID:12895659 RGD:1642798 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
negative regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Madd MAP-kinase activating death domain IMP RGD PMID:23702376 RGD:9588639 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 involved_in IEA
ISO
GO_REF:0000107
(MGI:3822255|PMID:18806227)
Ensembl
RGD
PMID:18806227 GO_REF:0000107 MGI:3822255 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
JBrowse link
G Stk39 serine threonine kinase 39 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 3:52,913,583...53,179,060
Ensembl chr 3:52,913,585...53,179,060
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
G Wnk3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr  X:20,156,260...20,299,252
Ensembl chr  X:20,157,041...20,296,821
JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 acts_upstream_of_or_within ISO (MGI:5002793|PMID:21317537) RGD PMID:21317537 MGI:5002793 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829
JBrowse link
positive regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Vamp8 vesicle-associated membrane protein 8 acts_upstream_of_or_within ISO MGI:3056083 (MGI:3801544|PMID:18535671) RGD PMID:18535671 MGI:3801544 NCBI chr 4:104,442,383...104,452,884
Ensembl chr 4:104,442,393...104,452,897
JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 involved_in ISO (MGI:3822255|PMID:18806227) RGD PMID:18806227 MGI:3822255 NCBI chr 1:95,041,967...95,047,377
Ensembl chr 1:95,041,967...95,047,377
JBrowse link
G Sct secretin involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:11123201 PMID:21873635 RGD:9590235, RGD:13792537 NCBI chr 1:196,382,941...196,383,635
Ensembl chr 1:196,382,856...196,383,658
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 IDA RGD PMID:2755938 RGD:10044250 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
positive regulation of pancreatic trypsinogen secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:12771515 RGD:724699 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19390
    multicellular organismal process 8821
      secretion by tissue 56
        pancreatic juice secretion 19
          negative regulation of pancreatic juice secretion 5
          pancreatic amylase secretion + 2
          pancreatic trypsinogen secretion + 1
          positive regulation of pancreatic juice secretion 3
          regulation of pancreatic juice secretion + 8
Path 2
Term Annotations click to browse term
  biological_process 19390
    localization 6437
      establishment of localization 4853
        transport 4689
          secretion 1159
            body fluid secretion 153
              pancreatic juice secretion 19
                negative regulation of pancreatic juice secretion 5
                pancreatic amylase secretion + 2
                pancreatic trypsinogen secretion + 1
                positive regulation of pancreatic juice secretion 3
                regulation of pancreatic juice secretion + 8
paths to the root