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ONTOLOGY REPORT - ANNOTATIONS


Term:AP-type membrane coat adaptor complex
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Accession:GO:0030119 term browser browse the term
Definition:Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
Synonyms:related_synonym: clathrin adaptor



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AP-type membrane coat adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2b1 adaptor related protein complex 2 subunit beta 1 part_of TAS PMID:8262066 PINC PMID:8262066 RGD:2306271 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap5b1 adaptor related protein complex 5 subunit beta 1 part_of ISO
ISS
IBA
(PMID:22022230)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:22022230 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:202,876,272...202,880,303
Ensembl chr 1:202,876,272...202,880,289
JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 part_of ISO
ISS
IBA
(PMID:22022230)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:22022230 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr15:22,355,478...22,385,222
Ensembl chr15:22,355,500...22,377,750
JBrowse link
G Ap5s1 adaptor related protein complex 5 subunit sigma 1 part_of IBA
ISO
PMID:21873635
(PMID:22022230)
RGD PMID:22022230 PMID:21873635 RGD:13792537 NCBI chr 3:118,429,618...118,436,256
Ensembl chr 3:118,429,637...118,432,926
JBrowse link
AP-1 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aftph aftiphilin part_of ISO
IBA
(PMID:15758025)
PMID:21873635
RGD PMID:15758025 PMID:21873635 RGD:13792537 NCBI chr14:94,871,429...94,925,625
Ensembl chr14:94,871,429...94,925,376
JBrowse link
G Ap1g2 adaptor related protein complex 1 subunit gamma 2 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:28,571,571...28,579,421
Ensembl chr15:28,571,568...28,589,004
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 9:80,950,402...81,039,685
Ensembl chr 9:80,950,715...81,009,798
JBrowse link
G Clba1 clathrin binding box of aftiphilin containing 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:131,882,866...131,889,662
Ensembl chr 6:131,882,609...131,889,662
JBrowse link
G Slc18a3 solute carrier family 18 member A3 part_of IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:14724281 PMID:21873635 RGD:2317430, RGD:13792537 NCBI chr16:7,713,630...7,716,491 JBrowse link
AP-2 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap2a1 adaptor related protein complex 2 subunit alpha 1 part_of ISO
IBA
(PMID:23676497)
(MGI:5514106|PMID:23676497)
PMID:21873635
RGD PMID:23676497 PMID:21873635 MGI:5514106, RGD:13792537 NCBI chr 1:95,384,303...95,414,249
Ensembl chr 1:95,384,309...95,414,147
JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 part_of IEA
ISO
IMP
IBA
GO_REF:0000002
GO_REF:0000107
(MGI:5514106|PMID:23676497)
PMID:12086608
PMID:21873635
(PMID:23676497)
InterPro
Ensembl
RGD
PMID:23676497 PMID:12086608 PMID:21873635 GO_REF:0000002 GO_REF:0000107 MGI:5514106, RGD:12793054, RGD:13792537 NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 part_of ISO (PMID:12086608), (PMID:23676497)
(MGI:5514106|PMID:23676497)
RGD PMID:12086608 PMID:23676497 MGI:5514106 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 part_of IDA
ISO
IBA
PMID:12086608
(MGI:5514106|PMID:23676497)
PMID:21873635
(PMID:23676497)
RGD PMID:23676497 PMID:12086608 PMID:21873635 MGI:5514106, RGD:12793054, RGD:13792537 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 part_of IDA
ISO
PMID:2040623
(MGI:5882913|PMID:12086608)
RGD PMID:12086608 PMID:7593184 PMID:2040623 MGI:5882913, RGD:2306270, RGD:727584 NCBI chr 1:77,417,496...77,428,903
Ensembl chr 1:77,417,477...77,428,905
JBrowse link
G Btbd8 BTB domain containing 8 colocalizes_with
part_of
IDA
ISO
PMID:29262337
(MGI:6104538|PMID:29262337)
(PMID:29262337)
RGD PMID:29262337 PMID:29262337 MGI:6104538, RGD:13601995 NCBI chr14:2,265,189...2,338,426
Ensembl chr14:2,266,454...2,334,393
JBrowse link
G Eps15 epidermal growth factor receptor pathway substrate 15 part_of ISO (MGI:4887327|PMID:17626015) RGD PMID:17626015 MGI:4887327 NCBI chr 5:124,045,865...124,146,221
Ensembl chr 5:124,045,926...124,146,221
JBrowse link
G Sgip1 SH3GL interacting endocytic adaptor 1 part_of ISS
ISO
IEA
PMID:17626015
(MGI:4887327|PMID:17626015)
GO_REF:0000107
RGD
Ensembl
PMID:17626015 PMID:17626015 GO_REF:0000107 MGI:4887327, RGD:8554282 NCBI chr 5:117,536,752...117,734,593
Ensembl chr 5:117,537,746...117,734,575
JBrowse link
G Slc18a3 solute carrier family 18 member A3 part_of IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:14724281 PMID:21873635 RGD:2317430, RGD:13792537 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Tbc1d5 TBC1 domain family, member 5 colocalizes_with
part_of
ISO
IEA
(PMID:24603492)
GO_REF:0000107
RGD
Ensembl
PMID:24603492 GO_REF:0000107 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
JBrowse link
AP-3 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 part_of IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191
JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 part_of IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643
JBrowse link
G Ap3s1 adaptor related protein complex 3 subunit sigma 1 part_of ISO (PMID:9118953) RGD PMID:9118953 NCBI chr18:39,462,727...39,531,626
Ensembl chr18:39,462,765...39,531,622
JBrowse link
G Ap3s2 adaptor related protein complex 3 subunit sigma 2 part_of ISO (PMID:9118953) RGD PMID:9118953 NCBI chr 1:133,818,825...133,859,269
Ensembl chr 1:133,818,825...133,859,322
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes part_of ISO (MGI:5645203|PMID:21411634) RGD PMID:21411634 MGI:5645203 NCBI chr 8:44,683,768...44,698,572
Ensembl chr 8:44,684,127...44,698,568
JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes part_of ISO (MGI:5645203|PMID:21411634) RGD PMID:21411634 MGI:5645203 NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441
JBrowse link
G Vps18 VPS18 core subunit of CORVET and HOPS complexes part_of ISO (MGI:5645203|PMID:21411634) RGD PMID:21411634 MGI:5645203 NCBI chr 3:106,279,444...106,290,298
Ensembl chr 3:106,279,425...106,291,964
JBrowse link
G Vps33a VPS33A core subunit of CORVET and HOPS complexes colocalizes_with ISO (PMID:21411634) RGD PMID:21411634 NCBI chr12:33,024,596...33,051,399
Ensembl chr12:33,024,650...33,051,393
JBrowse link
G Vps39 VPS39 subunit of HOPS complex part_of ISO (MGI:5645203|PMID:21411634) RGD PMID:21411634 MGI:5645203 NCBI chr 3:107,266,846...107,304,884
Ensembl chr 3:107,267,310...107,304,975
JBrowse link
G Vps41 VPS41 subunit of HOPS complex colocalizes_with IDA
ISO
PMID:24210660
(PMID:21411634)
RGD PMID:21411634 PMID:24210660 RGD:10054072 NCBI chr17:46,063,124...46,227,582
Ensembl chr17:46,063,124...46,227,791
JBrowse link
AP-4 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap4b1 adaptor related protein complex 4 subunit beta 1 part_of ISO (PMID:10066790) RGD PMID:10066790 NCBI chr 2:191,318,485...191,330,531
Ensembl chr 2:191,318,482...191,330,531
JBrowse link
G Ap4e1 adaptor related protein complex 4 subunit epsilon 1 part_of ISO
IBA
(PMID:10066790)
PMID:21873635
RGD PMID:10066790 PMID:21873635 RGD:13792537 NCBI chr 3:114,272,997...114,339,484
Ensembl chr 3:114,272,956...114,336,752
JBrowse link
G Ap4m1 adaptor related protein complex 4 subunit mu 1 part_of ISO
ISS
(PMID:10066790), (PMID:11802162)
GO_REF:0000024
RGD
UniProt
PMID:10066790 PMID:11802162 GO_REF:0000024 NCBI chr12:17,049,766...17,055,954
Ensembl chr12:17,049,777...17,058,026
JBrowse link
G Ap4s1 adaptor related protein complex 4 subunit sigma 1 part_of ISO (PMID:10066790) RGD PMID:10066790 NCBI chr 6:69,133,403...69,174,488
Ensembl chr 6:69,133,373...69,175,496
JBrowse link
G Tepsin TEPSIN, adaptor related protein complex 4 accessory protein colocalizes_with IDA
ISO
PMID:22472443
(PMID:22472443), (PMID:26756312)
RGD PMID:22472443 PMID:26756312 PMID:22472443 RGD:11250428 NCBI chr10:105,373,939...105,381,310
Ensembl chr10:105,373,941...105,382,266
JBrowse link
AP-5 adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07035428.1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002
G AABR07035428.2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002
clathrin adaptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1b1 adaptor related protein complex 1 subunit beta 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:79,879,482...79,930,778
Ensembl chr14:79,879,533...79,930,778
JBrowse link
G Ap1m1 adaptor related protein complex 1 subunit mu 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr16:17,586,886...17,602,410
Ensembl chr16:17,584,730...17,602,403
JBrowse link
G Ap1m2 adaptor related protein complex 1 subunit mu 2 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 8:19,838,579...19,856,560
Ensembl chr 8:19,838,580...19,856,482
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 part_of ISO (PMID:8262066) RGD PMID:8262066 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 part_of IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935
JBrowse link
G Ap3m1 adaptor related protein complex 3 subunit mu 1 part_of IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr15:3,246,616...3,264,846
Ensembl chr15:3,246,926...3,264,844
JBrowse link
G Ap3m2 adaptor related protein complex 3 subunit mu 2 part_of IEA GO_REF:0000104
GO_REF:0000002
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104 NCBI chr16:69,217,526...69,237,372
Ensembl chr16:69,217,633...69,235,431
JBrowse link
G Ap4b1 adaptor related protein complex 4 subunit beta 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:191,318,485...191,330,531
Ensembl chr 2:191,318,482...191,330,531
JBrowse link
G Ap4m1 adaptor related protein complex 4 subunit mu 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:17,049,766...17,055,954
Ensembl chr12:17,049,777...17,058,026
JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 IDA RGD PMID:12564930 RGD:727577 NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19896
    protein-containing complex 5946
      membrane protein complex 1234
        AP-type membrane coat adaptor complex 43
          AP-3 adaptor complex 11
          AP-4 adaptor complex 5
          AP-5 adaptor complex 2
          clathrin adaptor complex + 25
Path 2
Term Annotations click to browse term
  cellular_component 19896
    cellular anatomical entity 19599
      intracellular anatomical structure 14287
        cytoplasm 11289
          membrane coat 100
            AP-type membrane coat adaptor complex 43
              AP-3 adaptor complex 11
              AP-4 adaptor complex 5
              AP-5 adaptor complex 2
              clathrin adaptor complex + 25
paths to the root