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ONTOLOGY REPORT - ANNOTATIONS


Term:natural killer cell activation
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Accession:GO:0030101 term browser browse the term
Definition:The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
Synonyms:exact_synonym: NK cell activation



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natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag6 BAG cochaperone 6 involved_in ISO
IEA
(PMID:18852879)
GO_REF:0000107
RGD
Ensembl
PMID:18852879 GO_REF:0000107 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
JBrowse link
G Cd2 Cd2 molecule involved_in ISO (PMID:23006327) RGD PMID:23006327 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:23006327), (PMID:9916693) RGD PMID:9916693 PMID:23006327 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:2683927 (MGI:3813999|PMID:17082577)
GO_REF:0000107
RGD
Ensembl
PMID:17082577 GO_REF:0000107 MGI:3813999 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:1673147) RGD PMID:1673147 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il18 interleukin 18 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2136797|PMID:10227969)
Ensembl
RGD
PMID:10227969 GO_REF:0000107 MGI:2136797 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il18r1 interleukin 18 receptor 1 acts_upstream_of_or_within ISO MGI:2136765 (MGI:2136797|PMID:10227969) RGD PMID:10227969 MGI:2136797 NCBI chr 9:42,727,416...42,760,971
Ensembl chr 9:42,727,869...42,760,715
JBrowse link
G Il2rb interleukin 2 receptor subunit beta involved_in IMP
IBA
PMID:21873635 RGD
GO_Central
PMID:1469024 PMID:21873635 RGD:2303496, RGD:13792537 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
JBrowse link
G Itgb2 integrin subunit beta 2 IMP RGD PMID:9413744 RGD:1600235 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Klra5 killer cell lectin-like receptor, subfamily A, member 5 IMP RGD PMID:8642329 RGD:61085 NCBI chr 4:164,761,839...164,824,367
Ensembl chr 4:164,806,003...164,823,382
JBrowse link
G Klrb1c killer cell lectin like receptor B1C acts_upstream_of_or_within ISO (MGI:3849756|PMID:19535641) RGD PMID:19535641 MGI:3849756 NCBI chr 4:162,380,773...162,394,688
Ensembl chr 4:162,381,602...162,393,786
JBrowse link
G Klrk1 killer cell lectin like receptor K1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
PR:B1B212|UniProtKB:B1B213|UniProtKB:Q3TM01 (MGI:2450811|PMID:12645935), (MGI:3773822|PMID:18209064)
Ensembl
RGD
PMID:12645935 PMID:18209064 GO_REF:0000107 MGI:2450811 MGI:3773822 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
JBrowse link
G Ncr3 natural cytotoxicity triggering receptor 3 involved_in IBA
ISS
ISO
PMID:21873635
GO_REF:0000024
(PMID:18852879)
UniProt
RGD
PMID:18852879 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799
JBrowse link
G Prdx1 peroxiredoxin 1 involved_in ISO (PMID:8462106) RGD PMID:8462106 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (PMID:27776107) RGD PMID:27776107 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Ulbp1 UL16 binding protein 1 involved_in ISO (PMID:11239445) RGD PMID:11239445 NCBI chr 1:1,694,255...1,716,160 JBrowse link
natural killer cell activation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO
IBA
(PMID:11714776)
PMID:21873635
(MGI:3773416|PMID:15905190)
RGD PMID:11714776 PMID:15905190 PMID:21873635 MGI:3773416, RGD:13792537 NCBI chr13:84,018,887...84,036,612
Ensembl chr13:84,020,095...84,036,100
JBrowse link
G Ifna1 interferon, alpha 1 acts_upstream_of_or_within ISO (MGI:3828876|PMID:19130550) RGD PMID:19130550 MGI:3828876 NCBI chr 5:103,095,767...103,098,260
Ensembl chr 5:103,097,356...103,097,925
JBrowse link
G Ifna4 interferon, alpha 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3828876|PMID:19130550)
RGD PMID:19130550 PMID:21873635 MGI:3828876, RGD:13792537 NCBI chr 5:103,069,483...103,070,052
Ensembl chr 5:103,069,483...103,070,052
JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnb1 interferon beta 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifne interferon, epsilon involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,538,001...103,627,561
Ensembl chr 5:103,569,675...103,572,256
JBrowse link
G Ifnk interferon kappa involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281
JBrowse link
G Il12b interleukin 12B IMP RGD PMID:14960310 RGD:1600048 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G LOC100911527 interferon alpha-12-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302
JBrowse link
G RGD1560539 similar to interferon alpha 8/6 precursor; IFNa8/6 (B6) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,476,362...103,477,211
Ensembl chr 5:103,476,657...103,477,211
JBrowse link
natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1a coronin 1A involved_in ISO (PMID:24760828) RGD PMID:24760828 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:25786175), (PMID:28652325) RGD PMID:25786175 PMID:28652325 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Nkg7 natural killer cell granule protein 7 involved_in ISO (MGI:6506882|PMID:32839608), (MGI:6810811|PMID:33911019) RGD PMID:32839608 PMID:33911019 MGI:6506882 MGI:6810811 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Rab27a RAB27A, member RAS oncogene family acts_upstream_of_or_within ISO MGI:1856656 (MGI:3653524|PMID:11266473) RGD PMID:11266473 MGI:3653524 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829
JBrowse link
G Stx11 syntaxin 11 acts_upstream_of_or_within ISO MGI:5461477 (MGI:5460953|PMID:23042080), (MGI:5471188|PMID:23190531) RGD PMID:23042080 PMID:23190531 MGI:5460953 MGI:5471188 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Unc13d unc-13 homolog D involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3628822 (MGI:3703574|PMID:17420270)
Ensembl
RGD
PMID:17420270 GO_REF:0000107 MGI:3703574 NCBI chr10:101,296,755...101,311,513
Ensembl chr10:101,296,776...101,311,687
JBrowse link
G Vamp2 vesicle-associated membrane protein 2 NOT|involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18042464) RGD PMID:18042464 NCBI chr12:16,728,477...16,764,261
Ensembl chr12:16,728,524...16,764,097
JBrowse link
natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:104294|MGI:96965 (MGI:3662985|PMID:16751775)
RGD PMID:16751775 PMID:21873635 MGI:3662985, RGD:13792537 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand acts_upstream_of ISO MGI:2158499 (MGI:3701546|PMID:14607906) RGD PMID:14607906 MGI:3701546 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:2137552 (MGI:5604339|PMID:24855001) RGD PMID:24855001 MGI:5604339 NCBI chr 6:69,181,429...69,267,803
Ensembl chr 6:69,181,436...69,268,053
JBrowse link
G Id2 inhibitor of DNA binding 2 acts_upstream_of_or_within ISO MGI:2384134|MGI:98510 (MGI:3759740|PMID:17452521) RGD PMID:17452521 MGI:3759740 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 acts_upstream_of_or_within ISO MGI:2158738 (MGI:68746|PMID:7923373) RGD PMID:7923373 MGI:68746 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il11ra1 interleukin 11 receptor subunit alpha 1 acts_upstream_of_or_within ISO MGI:2177774 (MGI:3505799|PMID:15499555) RGD PMID:15499555 MGI:3505799 NCBI chr 5:56,931,824...56,941,408
Ensembl chr 5:56,935,516...56,941,408
JBrowse link
G Il15 interleukin 15 acts_upstream_of
involved_in
ISO
IEA
MGI:2136897 (MGI:3701546|PMID:14607906)
GO_REF:0000107
RGD
Ensembl
PMID:14607906 GO_REF:0000107 MGI:3701546 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha acts_upstream_of ISO MGI:1934016 (MGI:3701546|PMID:14607906) RGD PMID:14607906 MGI:3701546 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
JBrowse link
G Il21 interleukin 21 acts_upstream_of ISO (MGI:3028812|PMID:14764669) RGD PMID:14764669 MGI:3028812 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Kat7 lysine acetyltransferase 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:6393224|PMID:27733580)
UniProt
RGD
PMID:27733580 GO_REF:0000024 MGI:6393224 NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase acts_upstream_of_or_within ISO MGI:104294|MGI:1347244 (MGI:3662985|PMID:16751775) RGD PMID:16751775 MGI:3662985 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
JBrowse link
G Nfil3 nuclear factor, interleukin 3 regulated involved_in ISS
ISO
GO_REF:0000024
(MGI:6460593|PMID:32190943)
UniProt
RGD
PMID:32190943 GO_REF:0000024 MGI:6460593 NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
JBrowse link
G Pbx1 PBX homeobox 1 involved_in ISO (MGI:6460593|PMID:32190943) RGD PMID:32190943 MGI:6460593 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C involved_in ISO (MGI:3521537|PMID:15557316) RGD PMID:15557316 MGI:3521537 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Rabl3 RAB, member of RAS oncogene family-like 3 involved_in ISO (MGI:6405642|PMID:32220963) RGD PMID:32220963 MGI:6405642 NCBI chr11:63,153,281...63,182,240
Ensembl chr11:63,152,792...63,182,671
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:3763993|PMID:18031695) RGD PMID:18031695 MGI:3763993 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (MGI:3763993|PMID:18031695) RGD PMID:18031695 MGI:3763993 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
JBrowse link
G Sp3 Sp3 transcription factor acts_upstream_of_or_within ISO MGI:2182438 (MGI:2670314|PMID:12676787) RGD PMID:12676787 MGI:2670314 NCBI chr 3:57,811,855...57,857,150
Ensembl chr 3:57,812,075...57,860,342
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:103035 (MGI:1332382|PMID:10072077)
MGI:1857249 (MGI:3655409|PMID:9841920)
RGD PMID:9841920 PMID:10072077 MGI:1332382 MGI:3655409 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)
MGI:103036 (MGI:1332382|PMID:10072077)
Ensembl
RGD
PMID:9841920 PMID:10072077 GO_REF:0000107 MGI:1332382 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Tcf3 transcription factor 3 acts_upstream_of_or_within ISO MGI:96397 (MGI:3759740|PMID:17452521) RGD PMID:17452521 MGI:3759740 NCBI chr 7:9,280,571...9,302,315
Ensembl chr 7:9,280,571...9,302,314
JBrowse link
G Tox thymocyte selection-associated high mobility group box involved_in ISO (PMID:21126536) RGD PMID:21126536 NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272
JBrowse link
G Tusc2 tumor suppressor 2, mitochondrial calcium regulator acts_upstream_of_or_within ISO MGI:103014|MGI:3706236 (MGI:3703651|PMID:17318811) RGD PMID:17318811 MGI:3703651 NCBI chr 8:108,236,838...108,240,056
Ensembl chr 8:108,236,838...108,240,056
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase acts_upstream_of_or_within ISO MGI:1347244|MGI:96965 (MGI:3662985|PMID:16751775) RGD PMID:16751775 MGI:3662985 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
JBrowse link
G Zfp683 zinc finger protein 683 acts_upstream_of_or_within ISO MGI:4276801 (MGI:5437828|PMID:22885984) RGD PMID:22885984 MGI:5437828 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
JBrowse link
natural killer cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elf4 E74 like ETS transcription factor 4 involved_in ISO (MGI:2388503|PMID:12387738) RGD PMID:12387738 MGI:2388503 NCBI chr  X:127,587,401...127,639,063
Ensembl chr  X:127,590,650...127,630,200
JBrowse link
G Emp2 epithelial membrane protein 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5908305|PMID:28295343)
UniProt
RGD
PMID:28295343 GO_REF:0000024 MGI:5908305 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733
JBrowse link
G Il15 interleukin 15 acts_upstream_of
involved_in
ISO
IEA
(MGI:3701546|PMID:14607906)
GO_REF:0000107
RGD
Ensembl
PMID:14607906 GO_REF:0000107 MGI:3701546 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 involved_in ISO (MGI:3763993|PMID:18031695) RGD PMID:18031695 MGI:3763993 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497
JBrowse link
G Slamf6 SLAM family member 6 involved_in ISO (MGI:3763993|PMID:18031695) RGD PMID:18031695 MGI:3763993 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300
JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of
involved_in
ISO
IEA
MGI:2181592 (MGI:3655409|PMID:9841920)
GO_REF:0000107
RGD
Ensembl
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
negative regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clnk cytokine-dependent hematopoietic cell linker involved_in ISO (MGI:3047506|PMID:15199160), (MGI:3774350|PMID:16439675) RGD PMID:15199160 PMID:16439675 MGI:3047506 MGI:3774350 NCBI chr14:71,923,894...72,101,180
Ensembl chr14:71,873,105...72,101,208
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in ISO (MGI:3774350|PMID:16439675) RGD PMID:16439675 MGI:3774350 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5705210|PMID:25337993) RGD PMID:25337993 MGI:5705210 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137
JBrowse link
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:20068167) RGD PMID:20068167 NCBI chr 1:78,372,138...78,398,932
Ensembl chr 1:78,372,802...78,398,930
JBrowse link
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:12516630) RGD PMID:12516630 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Rhbdd3 rhomboid domain containing 3 acts_upstream_of_or_within ISO MGI:5516031 (MGI:5492204|PMID:23610400) RGD PMID:23610400 MGI:5492204 NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:3,403,418...3,479,476 JBrowse link
negative regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pglyrp1 peptidoglycan recognition protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2670590 (MGI:5297102|PMID:20709292)
Ensembl
RGD
PMID:20709292 GO_REF:0000107 MGI:5297102 NCBI chr 1:78,531,815...78,537,001
Ensembl chr 1:78,531,815...78,537,001
JBrowse link
G Pglyrp2 peptidoglycan recognition protein 2 acts_upstream_of_or_within ISO MGI:5297105 (MGI:5297102|PMID:20709292) RGD PMID:20709292 MGI:5297102 NCBI chr 7:11,418,674...11,432,162
Ensembl chr 7:11,418,880...11,427,773
JBrowse link
G Pglyrp3 peptidoglycan recognition protein 3 acts_upstream_of_or_within ISO MGI:5297106 (MGI:5297102|PMID:20709292) RGD PMID:20709292 MGI:5297102 NCBI chr 2:177,479,693...177,490,867
Ensembl chr 2:177,477,407...177,490,736
JBrowse link
G Pglyrp4 peptidoglycan recognition protein 4 acts_upstream_of_or_within ISO MGI:5297107 (MGI:5297102|PMID:20709292) RGD PMID:20709292 MGI:5297102 NCBI chr 2:176,202,654...176,322,859
Ensembl chr 2:176,218,519...176,242,251
JBrowse link
positive regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 acts_upstream_of_or_within ISO MGI:1857021 (MGI:55273|PMID:7089489) RGD PMID:7089489 MGI:55273 NCBI chr 1:79,155,914...79,158,326
Ensembl chr 1:79,155,693...79,158,505
JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO MGI:1856982 (MGI:55273|PMID:7089489) RGD PMID:7089489 MGI:55273 NCBI chr 3:109,816,397...109,826,528
Ensembl chr 3:109,816,366...109,828,308
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 acts_upstream_of_or_within ISO MGI:1856712 (MGI:55273|PMID:7089489) RGD PMID:7089489 MGI:55273 NCBI chr 1:241,551,180...241,577,292
Ensembl chr 1:241,551,175...241,577,268
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:1674604) RGD PMID:1674604 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:1674604) RGD PMID:1674604 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Lyst lysosomal trafficking regulator acts_upstream_of_or_within ISO MGI:1855968 (MGI:55273|PMID:7089489) RGD PMID:7089489 MGI:55273 NCBI chr17:86,241,384...86,443,501
Ensembl chr17:86,241,384...86,443,480
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (MGI:5302428|PMID:21957144) RGD PMID:21957144 MGI:5302428 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Ticam1 toll-like receptor adaptor molecule 1 acts_upstream_of_or_within ISO MGI:3701472 (MGI:5293306|PMID:21059856) RGD PMID:21059856 MGI:5293306 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp involved_in IBA
ISO
PMID:21873635
(MGI:1276991|PMID:9647200)
RGD PMID:9647200 PMID:21873635 MGI:1276991, RGD:13792537 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (MGI:2450811|PMID:12645935) RGD PMID:12645935 MGI:2450811 NCBI chr 1:1,694,255...1,716,160 JBrowse link
positive regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1g1 adaptor related protein complex 1 subunit gamma 1 involved_in ISO (PMID:23632890) RGD PMID:23632890 NCBI chr19:37,744,666...37,831,131
Ensembl chr19:37,744,633...37,829,167
JBrowse link
G Cd160 CD160 molecule involved_in ISO (PMID:19109136) RGD PMID:19109136 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834
JBrowse link
G Klrc2 killer cell lectin like receptor C2 involved_in ISO (PMID:21825173) RGD PMID:21825173 NCBI chr 4:163,122,700...163,133,843
Ensembl chr 4:163,122,704...163,133,843
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 involved_in ISO
IEA
(PMID:23632890)
GO_REF:0000107
RGD
Ensembl
PMID:23632890 GO_REF:0000107 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:27455421) RGD PMID:27455421 NCBI chr20:3,403,418...3,479,476 JBrowse link
positive regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axl Axl receptor tyrosine kinase involved_in ISO (PMID:18840707) RGD PMID:18840707 NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand acts_upstream_of_or_within ISO MGI:2158499 (MGI:3701546|PMID:14607906) RGD PMID:14607906 MGI:3701546 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Gas6 growth arrest specific 6 involved_in ISS
ISO
GO_REF:0000024
(PMID:18840707)
UniProt
RGD
PMID:18840707 GO_REF:0000024 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO MGI:1931086|MGI:2136897 (MGI:3701546|PMID:14607906), (MGI:3703651|PMID:17318811) RGD PMID:14607906 PMID:17318811 MGI:3701546 MGI:3703651 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il15ra interleukin 15 receptor subunit alpha acts_upstream_of_or_within ISO MGI:1934016 (MGI:3701546|PMID:14607906) RGD PMID:14607906 MGI:3701546 NCBI chr17:66,802,300...66,831,973
Ensembl chr17:66,802,334...66,832,278
JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO (MGI:3028812|PMID:14764669) RGD PMID:14764669 MGI:3028812 NCBI chr 2:120,119,598...120,126,941
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in ISO (MGI:5302428|PMID:21957144) RGD PMID:21957144 MGI:5302428 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056
JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within ISO MGI:1857249 (MGI:3655409|PMID:9841920) RGD PMID:9841920 MGI:3655409 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)
Ensembl
RGD
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Tox thymocyte selection-associated high mobility group box acts_upstream_of_or_within ISO MGI:3773716 (MGI:4834966|PMID:20818394) RGD PMID:20818394 MGI:4834966 NCBI chr 5:19,874,994...20,171,272
Ensembl chr 5:19,874,467...20,171,272
JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 involved_in ISO (MGI:5446979|PMID:22753936) RGD PMID:22753936 MGI:5446979 NCBI chr 6:95,096,838...95,125,811
Ensembl chr 6:95,096,387...95,118,996
JBrowse link
positive regulation of natural killer cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd244 CD244 molecule involved_in ISO (MGI:3773416|PMID:15905190) RGD PMID:15905190 MGI:3773416 NCBI chr13:84,018,887...84,036,612
Ensembl chr13:84,020,095...84,036,100
JBrowse link
G Fcgr3a Fc gamma receptor 3A involved_in ISO (PMID:9916693) RGD PMID:9916693 NCBI chr13:83,249,905...83,259,921
Ensembl chr13:83,249,872...83,259,921
JBrowse link
G Flt3lg Fms related receptor tyrosine kinase 3 ligand IDA RGD PMID:16528542 RGD:11049499 NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463
JBrowse link
G Il12a interleukin 12A involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Il12b interleukin 12B involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il12rb1 interleukin 12 receptor subunit beta 1 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr16:18,620,228...18,633,207
Ensembl chr16:18,620,770...18,632,769
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289
JBrowse link
G Il15 interleukin 15 acts_upstream_of_or_within ISO (MGI:3701546|PMID:14607906) RGD PMID:14607906 MGI:3701546 NCBI chr19:25,640,013...25,706,818
Ensembl chr19:25,640,251...25,706,820
JBrowse link
G Il18 interleukin 18 involved_in ISO
IEA
(PMID:19088061)
GO_REF:0000107
RGD
Ensembl
PMID:19088061 GO_REF:0000107 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Jak2 Janus kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-S3 RT1 class Ib, locus S3 involved_in ISO (PMID:30134159) RGD PMID:30134159 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Stat5b signal transducer and activator of transcription 5B involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181592 (MGI:3655409|PMID:9841920)
Ensembl
RGD
PMID:9841920 GO_REF:0000107 MGI:3655409 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Tyk2 tyrosine kinase 2 involved_in ISO (PMID:19088061) RGD PMID:19088061 NCBI chr 8:19,641,881...19,667,157
Ensembl chr 8:19,641,884...19,667,044
JBrowse link
regulation of natural killer cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dcaf15 DDB1 and CUL4 associated factor 15 involved_in ISO (PMID:31452512) RGD PMID:31452512 NCBI chr19:24,053,925...24,061,277
Ensembl chr19:24,053,925...24,061,277
JBrowse link
G Lep leptin involved_in ISO
ISS
(PMID:12504075)
GO_REF:0000024
RGD
UniProt
PMID:12504075 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Sh2d1b2 SH2 domain containing 1B2 acts_upstream_of_or_within ISO MGI:1922595 (MGI:3836377|PMID:19151721) RGD PMID:19151721 MGI:3836377 NCBI chr13:82,416,362...82,461,511
Ensembl chr13:82,437,428...82,461,509
JBrowse link
G Slamf7 SLAM family member 7 acts_upstream_of_or_within ISO MGI:3622649 (MGI:3836377|PMID:19151721) RGD PMID:19151721 MGI:3836377 NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105
JBrowse link
regulation of natural killer cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 involved_in ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Prdm1 PR/SET domain 1 involved_in ISO (MGI:5779429|PMID:27102484) RGD PMID:27102484 MGI:5779429 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Zfp683 zinc finger protein 683 involved_in ISO (MGI:5779429|PMID:27102484) RGD PMID:27102484 MGI:5779429 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
JBrowse link
regulation of natural killer cell differentiation involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zfp683 zinc finger protein 683 involved_in ISO (MGI:5437828|PMID:22885984) RGD PMID:22885984 MGI:5437828 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
JBrowse link
regulation of natural killer cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lep leptin involved_in ISO
ISS
(PMID:12504075)
GO_REF:0000024
RGD
UniProt
PMID:12504075 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Ptpn22 protein tyrosine phosphatase, non-receptor type 22 involved_in ISO
ISS
(PMID:20522204)
GO_REF:0000024
RGD
BHF-UCL
PMID:20522204 GO_REF:0000024 NCBI chr 2:191,366,761...191,414,782
Ensembl chr 2:191,366,808...191,414,779
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    immune system process 2730
      leukocyte activation 1025
        lymphocyte activation 840
          natural killer cell activation 97
            establishment of natural killer cell polarity 0
            natural killer cell activation involved in immune response + 29
            natural killer cell differentiation + 34
            natural killer cell proliferation + 21
            negative regulation of natural killer cell activation + 12
            positive regulation of natural killer cell activation + 35
            regulation of natural killer cell activation + 53
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cell activation 1172
        leukocyte activation 1025
          lymphocyte activation 840
            natural killer cell activation 97
              establishment of natural killer cell polarity 0
              natural killer cell activation involved in immune response + 29
              natural killer cell differentiation + 34
              natural killer cell proliferation + 21
              negative regulation of natural killer cell activation + 12
              positive regulation of natural killer cell activation + 35
              regulation of natural killer cell activation + 53
paths to the root