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ONTOLOGY REPORT - ANNOTATIONS

Term:insulin secretion
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Accession:GO:0030073 term browser browse the term
Definition:The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
Synonyms:only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1c activin A receptor, type IC acts_upstream_of IMP (PMID:18480258) MGI PMID:18480258 NCBI chr 2:58,157,465...58,247,909
Ensembl chr 2:58,157,465...58,247,907 		JBrowse link
G Acvr2b activin receptor IIB acts_upstream_of_or_within IGI (PMID:17849440) MGI PMID:17849440 NCBI chr 9:119,231,081...119,271,214
Ensembl chr 9:119,231,184...119,264,061 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in IDA (MGI:5525944|PMID:23913443) UniProt PMID:23913443 MGI:5525944 NCBI chr17:93,506,448...93,513,967
Ensembl chr17:93,506,445...93,513,965 		JBrowse link
G Anxa1 annexin A1 involved_in ISO RGD
MGI		 PMID:12459455 GO_REF:0000096 MGI:4417868 RGD:628365 NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308 		JBrowse link
G Anxa7 annexin A7 acts_upstream_of IGI (PMID:20440069) MGI PMID:20440069 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201 		JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit acts_upstream_of_or_within IMP (PMID:12881419) MGI PMID:12881419 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851 		JBrowse link
G Cckar cholecystokinin A receptor involved_in ISO RGD
MGI		 PMID:9773935 GO_REF:0000096 MGI:4417868 RGD:2313338 NCBI chr 5:53,855,827...53,865,046
Ensembl chr 5:53,855,118...53,865,047 		JBrowse link
G Cplx1 complexin 1 involved_in IMP (MGI:3688343|PMID:15126625) UniProt PMID:15126625 MGI:3688343 NCBI chr 5:108,666,420...108,697,893
Ensembl chr 5:108,666,420...108,697,890 		JBrowse link
G Cplx3 complexin 3 involved_in IMP (MGI:3582382|PMID:15911881) UniProt PMID:15911881 MGI:3582382 NCBI chr 9:57,507,275...57,513,564
Ensembl chr 9:57,507,275...57,513,564 		JBrowse link
G Cyb5r4 cytochrome b5 reductase 4 acts_upstream_of_or_within IMP (PMID:15247412) MGI PMID:15247412 NCBI chr 9:86,904,082...86,959,827
Ensembl chr 9:86,904,067...86,959,827 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 involved_in ISO RGD
MGI		 PMID:12193544 GO_REF:0000096 MGI:4417868 RGD:628375 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153 		JBrowse link
G Fam3b FAM3 metabolism regulating signaling molecule B involved_in IDA
IBA
ISO		 (MGI:2384458|PMID:12160727) UniProt
GO_Central
MGI		 PMID:12160727 GO_REF:0000033 GO_REF:0000119 MGI:2384458 MGI:4834177 NCBI chr16:97,272,165...97,306,136
Ensembl chr16:97,272,165...97,316,016 		JBrowse link
G Ffar1 free fatty acid receptor 1 acts_upstream_of_or_within IMP (PMID:17395749) MGI PMID:17395749 NCBI chr 7:30,559,993...30,560,895
Ensembl chr 7:30,556,815...30,560,989 		JBrowse link
G Fkbp1b FK506 binding protein 1b acts_upstream_of_or_within IMP (PMID:18466757) MGI PMID:18466757 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765 		JBrowse link
G Gpr119 G-protein coupled receptor 119 acts_upstream_of_or_within IDA (PMID:15607732) MGI PMID:15607732 NCBI chr  X:47,756,856...47,763,355
Ensembl chr  X:47,756,856...47,763,355 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of IMP (PMID:19213841) MGI PMID:19213841 NCBI chr 1:125,604,725...125,804,132
Ensembl chr 1:125,604,732...125,801,599 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of IMP (PMID:22733973) MGI PMID:22733973 NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457 		JBrowse link
G Hmga1 high mobility group AT-hook 1 acts_upstream_of_or_within IMP (PMID:15924147) MGI PMID:15924147 NCBI chr17:27,774,798...27,782,649
Ensembl chr17:27,775,471...27,782,648 		JBrowse link
G Hnf1a HNF1 homeobox A involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:9566924), (PMID:9733737)
(PMID:15142986), (PMID:9593777)		 MGI PMID:9566924 PMID:9593777 PMID:9733737 PMID:15142986 GO_REF:0000119 MGI:4834177 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Hnf1b HNF1 homeobox B acts_upstream_of_or_within IMP (PMID:15142986) MGI PMID:15142986 NCBI chr11:83,741,035...83,796,743
Ensembl chr11:83,740,889...83,796,645 		JBrowse link
G Htt huntingtin acts_upstream_of_or_within IMP (PMID:10078572) MGI PMID:10078572 NCBI chr 5:34,919,084...35,069,878
Ensembl chr 5:34,919,084...35,069,878 		JBrowse link
G Il1rn interleukin 1 receptor antagonist acts_upstream_of_or_within IMP (PMID:12975454) MGI PMID:12975454 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506 		JBrowse link
G Ildr2 immunoglobulin-like domain containing receptor 2 acts_upstream_of_or_within IMP (PMID:18654634) MGI PMID:18654634 NCBI chr 1:166,081,630...166,144,405
Ensembl chr 1:166,081,708...166,144,392 		JBrowse link
G Irs1 insulin receptor substrate 1 NOT|acts_upstream_of_or_within IMP (PMID:9062343) MGI PMID:9062343 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Lep leptin acts_upstream_of_or_within IGI (PMID:16141392) MGI PMID:16141392 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Mafa MAF bZIP transcription factor A acts_upstream_of
involved_in		 ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr15:75,617,350...75,620,170
Ensembl chr15:75,617,339...75,620,077 		JBrowse link
G Mc4r melanocortin 4 receptor acts_upstream_of_or_within IGI (PMID:16141392) MGI PMID:16141392 NCBI chr18:66,990,776...66,993,558
Ensembl chr18:66,990,775...66,993,577 		JBrowse link
G Myo5a myosin VA acts_upstream_of_or_within IMP (PMID:15788565) MGI PMID:15788565 NCBI chr 9:74,975,183...75,130,970
Ensembl chr 9:74,978,297...75,130,970 		JBrowse link
G Neurod1 neurogenic differentiation 1 acts_upstream_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:79,282,981...79,286,980
Ensembl chr 2:79,282,865...79,287,095 		JBrowse link
G Nnat neuronatin acts_upstream_of IMP (PMID:15793245) MGI PMID:15793245 NCBI chr 2:157,401,936...157,404,445
Ensembl chr 2:157,401,998...157,404,442 		JBrowse link
G Park7 Parkinson disease (autosomal recessive, early onset) 7 involved_in IMP (MGI:5908331|PMID:22611253) UniProt PMID:22611253 MGI:5908331 NCBI chr 4:150,981,590...150,994,378
Ensembl chr 4:150,981,590...150,998,894 		JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) acts_upstream_of_or_within IDA (PMID:12401793) MGI PMID:12401793 NCBI chr 5:14,564,924...14,913,479
Ensembl chr 5:14,564,932...14,913,473 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of IMP (PMID:12837755) MGI PMID:12837755 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Ptprn protein tyrosine phosphatase receptor type N involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:75,223,679...75,241,437
Ensembl chr 1:75,223,671...75,241,146 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in IPI (PMID:11056535) MGI PMID:11056535 NCBI chr 8:71,207,258...71,211,276
Ensembl chr 8:71,207,328...71,211,323 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor (GEF) 4 acts_upstream_of_or_within IDA (PMID:11598134), (PMID:12401793) MGI PMID:11598134 PMID:12401793 NCBI chr 2:71,811,559...72,087,818
Ensembl chr 2:71,811,584...72,087,818 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in
acts_upstream_of_or_within		 IMP
IDA		 (PMID:11598134) MGI PMID:11598134 NCBI chr15:39,061,681...39,547,768
Ensembl chr15:39,061,656...39,547,768 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 acts_upstream_of IMP (PMID:16415102) MGI PMID:16415102 NCBI chr 3:58,429,390...58,433,305
Ensembl chr 3:58,427,238...58,433,313 		JBrowse link
G Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 involved_in ISO RGD
MGI		 PMID:18577569 GO_REF:0000096 MGI:4417868 RGD:2317338 NCBI chr19:59,249,310...59,284,444
Ensembl chr19:59,249,328...59,284,444 		JBrowse link
G Slc30a8 solute carrier family 30 (zinc transporter), member 8 involved_in IMP
IBA
ISO		 (MGI:4359332|PMID:19450229) BHF-UCL
GO_Central
MGI
RGD		 PMID:19450229 PMID:19479076 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4359332 MGI:4417868 MGI:4834177 RGD:2315022 NCBI chr15:52,158,949...52,199,194
Ensembl chr15:52,158,949...52,199,194 		JBrowse link
G Smad2 SMAD family member 2 acts_upstream_of_or_within IGI (PMID:17849440) MGI PMID:17849440 NCBI chr18:76,369,898...76,444,819
Ensembl chr18:76,374,651...76,444,034 		JBrowse link
G Snap25 synaptosomal-associated protein 25 involved_in ISO (PMID:20643776) MGI PMID:20643776 NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348 		JBrowse link
G Snord32a small nucleolar RNA, C/D box 32A acts_upstream_of_or_within IGI (PMID:27820699) MGI PMID:27820699 NCBI chr 7:44,776,807...44,776,887
Ensembl chr 7:44,776,806...44,776,888 		JBrowse link
G Snord33 small nucleolar RNA, C/D box 33 acts_upstream_of_or_within IGI (PMID:27820699) MGI PMID:27820699 NCBI chr 7:44,776,288...44,776,369
Ensembl chr 7:44,776,288...44,776,371 		JBrowse link
G Snord34 small nucleolar RNA, C/D box 34 acts_upstream_of_or_within IGI (PMID:27820699) MGI PMID:27820699 NCBI chr 7:44,776,027...44,776,092
Ensembl chr 7:44,776,025...44,776,094 		JBrowse link
G Snord35a small nucleolar RNA, C/D box 35A acts_upstream_of_or_within IGI (PMID:27820699) MGI PMID:27820699 NCBI chr 7:44,775,771...44,775,859
Ensembl chr 7:44,775,770...44,775,859 		JBrowse link
G Snx19 sorting nexin 19 involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:24843546) MGI PMID:24843546 GO_REF:0000119 MGI:4834177 NCBI chr 9:30,338,284...30,378,437
Ensembl chr 9:30,338,404...30,378,029 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of IMP (PMID:16890542) MGI PMID:16890542 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Stx1a syntaxin 1A (brain) involved_in IMP (MGI:3789566|PMID:17502420) UniProt PMID:17502420 MGI:3789566 NCBI chr 5:135,051,473...135,079,954
Ensembl chr 5:135,052,336...135,079,954 		JBrowse link
G Stxbp3 syntaxin binding protein 3 acts_upstream_of_or_within IMP (PMID:19188424) MGI PMID:19188424 NCBI chr 3:108,700,496...108,747,818
Ensembl chr 3:108,700,492...108,747,842 		JBrowse link
G Sytl4 synaptotagmin-like 4 acts_upstream_of IMP (PMID:16890542) MGI PMID:16890542 NCBI chr  X:132,837,134...132,882,569
Ensembl chr  X:132,837,134...132,882,561 		JBrowse link
G Vgf VGF nerve growth factor inducible acts_upstream_of_or_within IGI (PMID:16141392) MGI PMID:16141392 NCBI chr 5:137,054,156...137,062,205
Ensembl chr 5:137,055,246...137,062,205 		JBrowse link
insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 acts_upstream_of IMP (PMID:24105478) MGI PMID:24105478 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Ccdc186 coiled-coil domain containing 186 acts_upstream_of_or_within IMP (PMID:27293546) MGI PMID:27293546 NCBI chr19:56,775,917...56,810,631
Ensembl chr19:56,775,913...56,810,622 		JBrowse link
G Cltrn collectrin, amino acid transport regulator acts_upstream_of_positive_effect ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:162,873,183...162,901,855
Ensembl chr  X:162,871,826...162,901,856 		JBrowse link
G Fkbp1b FK506 binding protein 1b acts_upstream_of IMP (PMID:19805579) MGI PMID:19805579 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of IMP (PMID:19213833) MGI PMID:19213833 NCBI chr 1:125,604,725...125,804,132
Ensembl chr 1:125,604,732...125,801,599 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of IMP (PMID:20440072) MGI PMID:20440072 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Ptprn protein tyrosine phosphatase receptor type N involved_in IMP
IBA		 (MGI:3624867|PMID:12031972), (MGI:5141326|PMID:21732083) UniProt
GO_Central		 PMID:12031972 PMID:21732083 GO_REF:0000033 MGI:3624867 MGI:5141326 NCBI chr 1:75,223,679...75,241,437
Ensembl chr 1:75,223,671...75,241,146 		JBrowse link
G Ptprn2 protein tyrosine phosphatase receptor type N polypeptide 2 involved_in IMP
IBA		 (MGI:5141326|PMID:21732083) UniProt
GO_Central		 PMID:21732083 GO_REF:0000033 MGI:5141326 NCBI chr12:116,449,316...117,241,787
Ensembl chr12:116,449,340...117,240,469 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in IMP (MGI:4352608|PMID:19335615) UniProt PMID:19335615 MGI:4352608 NCBI chr17:33,961,458...33,979,460
Ensembl chr17:33,961,458...33,979,504 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 (class I) involved_in IMP (MGI:4352608|PMID:19335615) UniProt PMID:19335615 MGI:4352608 NCBI chr19:59,881,934...59,933,086
Ensembl chr19:59,891,316...59,932,086 		JBrowse link
G Rab11fip5 RAB11 family interacting protein 5 (class I) involved_in IMP (MGI:4352608|PMID:19335615) UniProt PMID:19335615 MGI:4352608 NCBI chr 6:85,311,944...85,351,663
Ensembl chr 6:85,311,944...85,351,616 		JBrowse link
G Raf1 v-raf-leukemia viral oncogene 1 acts_upstream_of_or_within IMP (PMID:21817126) MGI PMID:21817126 NCBI chr 6:115,595,530...115,653,596
Ensembl chr 6:115,595,028...115,653,596 		JBrowse link
G Rbm4 RNA binding motif protein 4 acts_upstream_of_or_within IMP (PMID:23129807) MGI PMID:23129807 NCBI chr19:4,834,321...4,844,037
Ensembl chr19:4,834,321...4,843,929 		JBrowse link
G Selenot selenoprotein T acts_upstream_of_or_within IMP (PMID:23913443) MGI PMID:23913443 NCBI chr 3:58,484,057...58,500,965
Ensembl chr 3:58,484,057...58,500,554 		JBrowse link
negative regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 involved_in ISO
IDA
IMP		 (PMID:25771886)
(PMID:16924481)		 RGD
MGI		 PMID:15163199 PMID:16924481 PMID:25771886 GO_REF:0000096 MGI:4417868 RGD:1598646 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Acvr1c activin A receptor, type IC acts_upstream_of_or_within IMP (PMID:18480258) MGI PMID:18480258 NCBI chr 2:58,157,465...58,247,909
Ensembl chr 2:58,157,465...58,247,907 		JBrowse link
G Adra2a adrenergic receptor, alpha 2a involved_in ISO
IMP
IDA		 (PMID:17992256), (PMID:1898674)
(PMID:1898674)		 MGI PMID:1898674 PMID:17992256 GO_REF:0000119 MGI:4834177 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413 		JBrowse link
G Bmp8a bone morphogenetic protein 8a involved_in ISO (PMID:22579288) UniProt PMID:22579288 NCBI chr 4:123,206,438...123,237,045
Ensembl chr 4:123,206,438...123,237,045 		JBrowse link
G Ccn3 cellular communication network factor 3 involved_in IDA (MGI:5517610|PMID:23705021) UniProt PMID:23705021 MGI:5517610 NCBI chr15:54,609,306...54,617,158
Ensembl chr15:54,609,098...54,617,435 		JBrowse link
G Chga chromogranin A involved_in IBA GO_Central GO_REF:0000033 NCBI chr12:102,521,200...102,531,286
Ensembl chr12:102,521,228...102,531,287 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO RGD
MGI		 PMID:18216393 GO_REF:0000096 MGI:4417868 RGD:2311570 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in IMP (PMID:17992256) MGI PMID:17992256 NCBI chr13:95,648,226...95,661,748
Ensembl chr13:95,648,240...95,661,735 		JBrowse link
G Fam3d FAM3 metabolism regulating signaling molecule D involved_in ISS
ISO		 (MGI:2384458|PMID:12160727) UniProt
MGI		 PMID:12160727 GO_REF:0000119 MGI:2384458 MGI:4834177 NCBI chr14:14,091,010...14,120,836
Ensembl chr14:14,091,019...14,120,836 		JBrowse link
G Fbn1 fibrillin 1 involved_in IDA (MGI:6442875|PMID:30997682) UniProt PMID:30997682 MGI:6442875 NCBI chr 2:125,142,514...125,348,417
Ensembl chr 2:125,142,514...125,349,913 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in IGI
IMP		 (PMID:25581519)
(PMID:26075576)		 MGI PMID:25581519 PMID:26075576 NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200 		JBrowse link
G Ffar3 free fatty acid receptor 3 involved_in IMP
IGI		 (PMID:26091414), (PMID:32073900)
(PMID:25581519)		 MGI PMID:25581519 PMID:26091414 PMID:32073900 NCBI chr 7:30,553,755...30,555,603
Ensembl chr 7:30,553,755...30,555,603 		JBrowse link
G Foxo1 forkhead box O1 involved_in IDA (MGI:2388494|PMID:12219087), (MGI:6101624|PMID:27457971) UniProt PMID:12219087 PMID:27457971 MGI:2388494 MGI:6101624 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642 		JBrowse link
G Ghrl ghrelin acts_upstream_of_or_within ISO
IMP		 (PMID:17130496) MGI PMID:17130496 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Ghsr growth hormone secretagogue receptor acts_upstream_of_or_within ISO (PMID:17130496) MGI PMID:17130496 NCBI chr 3:27,425,500...27,433,384
Ensembl chr 3:27,425,500...27,432,159 		JBrowse link
G Gnao1 guanine nucleotide binding protein, alpha O involved_in IMP (PMID:20622165) MGI PMID:20622165 NCBI chr 8:94,537,213...94,696,016
Ensembl chr 8:94,536,594...94,696,016 		JBrowse link
G Gnaz guanine nucleotide binding protein, alpha z subunit involved_in IMP (PMID:18096703) MGI PMID:18096703 NCBI chr10:74,803,009...74,852,739
Ensembl chr10:74,803,009...74,852,739 		JBrowse link
G Hadh hydroxyacyl-Coenzyme A dehydrogenase involved_in ISO RGD
MGI		 PMID:17491019 GO_REF:0000096 MGI:4417868 RGD:2302227 NCBI chr 3:131,027,068...131,065,750
Ensembl chr 3:131,027,068...131,065,750 		JBrowse link
G Hdac1 histone deacetylase 1 ISO RGD PMID:22772764 RGD:9590127 NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506 		JBrowse link
G Inhbb inhibin beta-B acts_upstream_of_or_within IMP (PMID:18480258) MGI PMID:18480258 NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978 		JBrowse link
G Irs1 insulin receptor substrate 1 involved_in ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137 		JBrowse link
G Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 involved_in IMP (MGI:3770494|PMID:17767909) UniProt PMID:17767909 MGI:3770494 NCBI chr 2:166,937,889...167,032,088
Ensembl chr 2:166,937,889...167,032,075 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 involved_in ISO
IMP		 (PMID:33196462)
(PMID:16924481)		 MGI PMID:16924481 PMID:33196462 GO_REF:0000119 MGI:4834177 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 involved_in TAS (PMID:34636409) MGI PMID:34636409 NCBI chr16:94,545,839...94,798,719
Ensembl chr16:94,549,495...94,798,560 		JBrowse link
G Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 involved_in ISO RGD
MGI		 PMID:16133261 GO_REF:0000096 MGI:4417868 RGD:1581603 NCBI chr 7:142,660,614...142,980,787
Ensembl chr 7:142,660,099...142,980,779 		JBrowse link
G Midn midnolin acts_upstream_of_or_within ISO (PMID:24187134) MGI PMID:24187134 NCBI chr10:79,984,106...79,994,202
Ensembl chr10:79,984,106...79,994,202 		JBrowse link
G Mtnr1a melatonin receptor 1A involved_in ISO RGD
MGI		 PMID:22288848 GO_REF:0000096 MGI:4417868 RGD:9686057 NCBI chr 8:45,522,144...45,542,270
Ensembl chr 8:45,522,174...45,541,543 		JBrowse link
G Mtnr1b melatonin receptor 1B involved_in ISO RGD
MGI		 PMID:18363673 GO_REF:0000096 MGI:4417868 RGD:9588673 NCBI chr 9:15,773,910...15,785,852
Ensembl chr 9:15,735,824...15,785,852 		JBrowse link
G Nos1 nitric oxide synthase 1, neuronal involved_in ISO RGD
MGI		 PMID:17130471 GO_REF:0000096 MGI:4417868 RGD:1642149 NCBI chr 5:118,004,904...118,096,905
Ensembl chr 5:117,919,097...118,096,905 		JBrowse link
G Npff neuropeptide FF-amide peptide precursor involved_in ISO RGD
MGI		 PMID:1704109 GO_REF:0000096 MGI:4417868 RGD:2316580 NCBI chr15:102,432,274...102,433,056
Ensembl chr15:102,432,274...102,433,377 		JBrowse link
G Pde8b phosphodiesterase 8B involved_in ISO RGD
MGI		 PMID:17991719 GO_REF:0000096 MGI:4417868 RGD:2312519 NCBI chr13:95,160,962...95,386,904
Ensembl chr13:95,160,962...95,386,844 		JBrowse link
G Pfkl phosphofructokinase, liver, B-type acts_upstream_of_or_within IDA (PMID:9287040) MGI PMID:9287040 NCBI chr10:77,822,781...77,845,641
Ensembl chr10:77,822,781...77,845,917 		JBrowse link
G Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 3:136,375,778...136,643,488
Ensembl chr 3:136,375,885...136,643,488 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 involved_in ISS
ISO		 (MGI:3611092|PMID:16099819) BHF-UCL
MGI		 PMID:16099819 GO_REF:0000096 MGI:3611092 MGI:4417868 NCBI chr 5:123,366,253...123,388,189
Ensembl chr 5:123,307,476...123,388,194 		JBrowse link
G Ptger3 prostaglandin E receptor 3 (subtype EP3) involved_in ISO RGD
MGI		 PMID:10531320 GO_REF:0000096 MGI:4417868 RGD:10043332 NCBI chr 3:157,272,459...157,350,392
Ensembl chr 3:157,272,529...157,351,525 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within IMP (PMID:15520383) MGI PMID:15520383 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Ptprv protein tyrosine phosphatase receptor type V acts_upstream_of_or_within IMP (PMID:17693256) MGI PMID:17693256 NCBI chr 1:135,036,236...135,060,313
Ensembl chr 1:135,036,235...135,060,332 		JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:77,413,273...77,434,279
Ensembl chr 5:77,413,338...77,434,279 		JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 involved_in IMP (MGI:5619445|PMID:23092880) CACAO PMID:23092880 MGI:5619445 NCBI chr11:119,493,731...119,790,417
Ensembl chr11:119,493,731...119,790,402 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648 		JBrowse link
G Sirt4 sirtuin 4 involved_in
acts_upstream_of_or_within		 ISO
IMP
IGI		 (PMID:16959573) MGI PMID:16959573 GO_REF:0000119 MGI:4834177 NCBI chr 5:115,616,065...115,628,322
Ensembl chr 5:115,616,069...115,622,784 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within IMP (PMID:16890542) MGI PMID:16890542 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Stxbp5l syntaxin binding protein 5-like acts_upstream_of_or_within IDA (PMID:21998599) MGI PMID:21998599 NCBI chr16:36,927,437...37,205,377
Ensembl chr16:36,935,304...37,205,324 		JBrowse link
G Sytl4 synaptotagmin-like 4 acts_upstream_of_or_within IMP (PMID:16890542) MGI PMID:16890542 NCBI chr  X:132,837,134...132,882,569
Ensembl chr  X:132,837,134...132,882,561 		JBrowse link
G Uts2 urotensin 2 involved_in ISO RGD
MGI		 PMID:17931748 GO_REF:0000096 MGI:4417868 RGD:2306798 NCBI chr 4:151,081,554...151,086,267
Ensembl chr 4:151,081,554...151,086,267 		JBrowse link
G Vsnl1 visinin-like 1 acts_upstream_of_or_within IMP (PMID:16731532) MGI PMID:16731532 NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614 		JBrowse link
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra2a adrenergic receptor, alpha 2a involved_in ISO MGI GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 NCBI chr19:54,033,690...54,037,413
Ensembl chr19:54,032,582...54,037,413 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 involved_in ISO RGD
MGI		 PMID:17360501 GO_REF:0000096 MGI:4417868 RGD:2306172 NCBI chr 6:55,067,033...55,110,001
Ensembl chr 6:55,067,034...55,110,001 		JBrowse link
G Eny2 ENY2 transcription and export complex 2 subunit involved_in ISO RGD
MGI		 PMID:22649445 GO_REF:0000096 MGI:4417868 RGD:9590329 NCBI chr15:44,291,488...44,301,652
Ensembl chr15:44,291,438...44,301,652 		JBrowse link
G Fkbp1b FK506 binding protein 1b acts_upstream_of_or_within IMP (PMID:19805579) MGI PMID:19805579 NCBI chr12:4,883,174...4,891,736
Ensembl chr12:4,883,174...4,891,591 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase involved_in ISO RGD
MGI		 PMID:20610886 GO_REF:0000096 MGI:4417868 RGD:5508687 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444 		JBrowse link
G Jagn1 jagunal homolog 1 involved_in ISO RGD
MGI		 PMID:26882284 GO_REF:0000096 MGI:4417868 RGD:11520872 NCBI chr 6:113,419,478...113,425,190
Ensembl chr 6:113,419,530...113,425,190 		JBrowse link
G Klf7 Kruppel-like transcription factor 7 (ubiquitous) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:64,068,607...64,161,504
Ensembl chr 1:64,068,606...64,161,441 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO RGD
MGI		 PMID:19690174 GO_REF:0000096 MGI:4417868 RGD:7495848 NCBI chr 1:39,939,806...40,065,470
Ensembl chr 1:39,940,073...40,065,470 		JBrowse link
G Mup1 major urinary protein 1 involved_in IDA (MGI:3850893|PMID:19336396) UniProt PMID:19336396 MGI:3850893 NCBI chr 4:60,454,011...60,457,959
Ensembl chr 4:60,454,011...60,457,959 		JBrowse link
G Ndufaf2 NADH:ubiquinone oxidoreductase complex assembly factor 2 acts_upstream_of_or_within IMP (PMID:22587331) MGI PMID:22587331 NCBI chr13:108,189,123...108,295,189
Ensembl chr13:108,139,249...108,295,157 		JBrowse link
G Pde1c phosphodiesterase 1C involved_in ISO RGD
MGI		 PMID:18706893 GO_REF:0000096 MGI:4417868 RGD:2302857 NCBI chr 6:56,046,783...56,629,590
Ensembl chr 6:56,046,789...56,629,472 		JBrowse link
G Pde3b phosphodiesterase 3B, cGMP-inhibited involved_in ISO RGD
MGI		 PMID:18706893 GO_REF:0000096 MGI:4417868 RGD:2302857 NCBI chr 7:114,014,388...114,137,173
Ensembl chr 7:114,014,516...114,138,486 		JBrowse link
G Pde4c phosphodiesterase 4C, cAMP specific involved_in ISO RGD
MGI		 PMID:18706893 GO_REF:0000096 MGI:4417868 RGD:2302857 NCBI chr 8:71,176,485...71,203,835
Ensembl chr 8:71,176,369...71,203,835 		JBrowse link
G Pde8b phosphodiesterase 8B involved_in ISO RGD
MGI		 PMID:18706893 GO_REF:0000096 MGI:4417868 RGD:2302857 NCBI chr13:95,160,962...95,386,904
Ensembl chr13:95,160,962...95,386,844 		JBrowse link
G Pim3 proviral integration site 3 involved_in IMP (MGI:5294526|PMID:21099329) UniProt PMID:21099329 MGI:5294526 NCBI chr15:88,746,397...88,749,929
Ensembl chr15:88,746,389...88,749,929 		JBrowse link
G Ptpmt1 protein tyrosine phosphatase, mitochondrial 1 involved_in ISO RGD
MGI		 PMID:20167843 GO_REF:0000096 MGI:4417868 RGD:12904047 NCBI chr 2:90,741,057...90,748,395
Ensembl chr 2:90,739,060...90,748,389 		JBrowse link
G Tbc1d1 TBC1 domain family, member 1 involved_in ISO RGD
MGI		 PMID:28177704 GO_REF:0000096 MGI:4417868 RGD:150521607 NCBI chr 5:64,313,648...64,508,829
Ensembl chr 5:64,313,648...64,508,829 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) involved_in ISO RGD
MGI		 PMID:21172424 GO_REF:0000096 MGI:4417868 RGD:7204422 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
positive regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aacs acetoacetyl-CoA synthetase involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:17724028 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:2301019 NCBI chr 5:125,552,937...125,594,469
Ensembl chr 5:125,552,878...125,594,474 		JBrowse link
G Abat 4-aminobutyrate aminotransferase involved_in ISO RGD
MGI		 PMID:20695849 GO_REF:0000096 MGI:4417868 RGD:9588550 NCBI chr16:8,331,293...8,439,432
Ensembl chr16:8,331,293...8,439,432 		JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in IDA
IMP		 (PMID:9075801)
(PMID:25403481)		 MGI PMID:9075801 PMID:25403481 NCBI chr15:64,570,884...64,794,145
Ensembl chr15:64,568,933...64,794,145 		JBrowse link
G Anxa7 annexin A7 acts_upstream_of_or_within_positive_effect IMP (PMID:10570150) MGI PMID:10570150 NCBI chr14:20,505,344...20,530,009
Ensembl chr14:20,505,328...20,530,201 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in IMP (MGI:3778846|PMID:18223655) UniProt PMID:18223655 MGI:3778846 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bglap2 bone gamma-carboxyglutamate protein 2 acts_upstream_of_or_within IMP (PMID:17693256) MGI PMID:17693256 NCBI chr 3:88,285,043...88,286,008
Ensembl chr 3:88,285,043...88,286,006 		JBrowse link
G Blk B lymphoid kinase involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:63,610,286...63,654,636
Ensembl chr14:63,610,285...63,654,486 		JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit involved_in ISO RGD
MGI		 PMID:18562674 GO_REF:0000096 MGI:4417868 RGD:152177517 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851 		JBrowse link
G Capn10 calpain 10 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:92,862,130...92,875,670
Ensembl chr 1:92,862,098...92,875,663 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase involved_in ISO RGD
MGI		 PMID:24140090 GO_REF:0000096 MGI:4417868 RGD:11576293 NCBI chr  X:13,383,319...13,713,020
Ensembl chr  X:13,383,319...13,717,606 		JBrowse link
G Casr calcium-sensing receptor involved_in ISO RGD
MGI		 PMID:22566534 GO_REF:0000096 MGI:4417868 RGD:7205453 NCBI chr16:36,310,947...36,382,605
Ensembl chr16:36,314,058...36,382,503 		JBrowse link
G Cd38 CD38 antigen involved_in ISO RGD
MGI		 PMID:9664081 GO_REF:0000096 MGI:4417868 RGD:2307276 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3, cardiac involved_in IDA
IMP		 (PMID:20440069)
(PMID:16753580)		 MGI PMID:16753580 PMID:20440069 NCBI chr13:9,925,522...10,411,131
Ensembl chr13:9,925,522...10,410,883 		JBrowse link
G Doc2b double C2, beta involved_in IMP (MGI:4457249|PMID:17548353) UniProt PMID:17548353 MGI:4457249 NCBI chr11:75,659,096...75,686,886
Ensembl chr11:75,659,792...75,686,875 		JBrowse link
G F2 coagulation factor II involved_in IMP
IDA		 (PMID:26742564) MGI PMID:26742564 NCBI chr 2:91,442,742...91,466,799
Ensembl chr 2:91,455,665...91,466,759 		JBrowse link
G F2rl2 coagulation factor II thrombin receptor like 2 involved_in IDA
IGI		 (PMID:26742564) MGI PMID:26742564 NCBI chr13:95,833,428...95,839,276
Ensembl chr13:95,833,361...95,839,247 		JBrowse link
G Ffar1 free fatty acid receptor 1 involved_in IMP
IDA
IBA
ISO		 (MGI:5607397|PMID:24130766)
(PMID:31664108)		 UniProt
MGI
GO_Central
RGD		 PMID:16081037 PMID:24130766 PMID:31664108 GO_REF:0000033 GO_REF:0000096 MGI:4417868 MGI:5607397 RGD:2315053 NCBI chr 7:30,559,993...30,560,895
Ensembl chr 7:30,556,815...30,560,989 		JBrowse link
G Ffar2 free fatty acid receptor 2 involved_in IDA (PMID:26075576) MGI PMID:26075576 NCBI chr 7:30,517,778...30,523,200
Ensembl chr 7:30,517,773...30,523,200 		JBrowse link
G Gck glucokinase involved_in
acts_upstream_of_or_within		 IMP
ISO		 (MGI:3819280|PMID:18477811)
(PMID:7556622)
in response to glucose stimulation		 UniProt
MGI
RGD		 PMID:7556622 PMID:17028192 PMID:17360975 PMID:18477811 GO_REF:0000096 GO_REF:0000119 MGI:3819280 MGI:4417868 MGI:4834177 RGD:1581879 RGD:2301916 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081 		JBrowse link
G Ghrl ghrelin involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Gip gastric inhibitory polypeptide involved_in ISO
IDA
IGI		 (PMID:20138041), (PMID:9075801)
(PMID:33196462)		 RGD
MGI		 PMID:8958204 PMID:9075801 PMID:20138041 PMID:33196462 GO_REF:0000096 MGI:4417868 RGD:2312537 NCBI chr11:95,915,358...95,921,657
Ensembl chr11:95,915,371...95,921,657 		JBrowse link
G Gipr gastric inhibitory polypeptide receptor involved_in ISO
IMP
IGI		 (PMID:9165060)
(PMID:23099862)
(PMID:15111503)		 RGD
MGI		 PMID:9165060 PMID:11014226 PMID:15111503 PMID:23099862 GO_REF:0000096 MGI:4417868 RGD:2312607 NCBI chr 7:18,889,988...18,904,173
Ensembl chr 7:18,889,986...18,900,052 		JBrowse link
G Gja1 gap junction protein, alpha 1 involved_in ISO RGD
MGI		 PMID:24301293 GO_REF:0000096 MGI:4417868 RGD:8662441 NCBI chr10:56,253,297...56,266,519
Ensembl chr10:56,253,426...56,278,609 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor involved_in ISO RGD
MGI		 PMID:12093887 GO_REF:0000096 MGI:4417868 RGD:625448 NCBI chr17:31,120,841...31,155,484
Ensembl chr17:31,120,791...31,159,765 		JBrowse link
G Glrx glutaredoxin ISO RGD PMID:19299446 RGD:9686053 NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273 		JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 ISO
IGI		 (PMID:11502802)
(PMID:16959573)		 BHF-UCL
MGI		 PMID:11502802 PMID:16959573 NCBI chr14:34,032,684...34,066,990
Ensembl chr14:34,032,684...34,067,222 		JBrowse link
G Glul glutamate-ammonia ligase involved_in ISO ornithine alpha-ketoglutarate-induced secretion RGD
MGI		 PMID:12575909 GO_REF:0000096 MGI:4417868 RGD:2301557 NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469 		JBrowse link
G Gna11 guanine nucleotide binding protein, alpha 11 involved_in IGI
IMP		 (PMID:20440069)
(PMID:26075576)		 MGI PMID:20440069 PMID:26075576 NCBI chr10:81,364,558...81,380,996
Ensembl chr10:81,364,558...81,381,024 		JBrowse link
G Gnaq guanine nucleotide binding protein, alpha q polypeptide involved_in IGI
IMP		 (PMID:20440069)
(PMID:26075576)		 MGI PMID:20440069 PMID:26075576 NCBI chr19:16,110,048...16,365,884
Ensembl chr19:16,110,195...16,364,827 		JBrowse link
G Gnas GNAS complex locus involved_in IMP
IGI
IDA		 (PMID:34091063)
(PMID:33196462)
(PMID:17971513)		 MGI PMID:17971513 PMID:33196462 PMID:34091063 NCBI chr 2:174,126,113...174,188,537
Ensembl chr 2:174,126,113...174,188,537 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 involved_in IDA (MGI:5141337|PMID:21673097) UniProt PMID:21673097 MGI:5141337 NCBI chr 5:139,408,905...139,413,555
Ensembl chr 5:139,408,906...139,413,555 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within IMP (PMID:19213841) MGI PMID:19213841 NCBI chr 1:125,604,725...125,804,132
Ensembl chr 1:125,604,732...125,801,599 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within IMP (PMID:22733973) MGI PMID:22733973 NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457 		JBrowse link
G Hnf1a HNF1 homeobox A ISO RGD PMID:10944108 RGD:150540301 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in IMP (MGI:4456946|PMID:15572028) BHF-UCL PMID:15572028 MGI:4456946 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458 		JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain involved_in ISO MGI
RGD		 PMID:11978636 PMID:29678908 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:243065231 RGD:729103 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 involved_in IGI
IMP		 (PMID:10570150)
(PMID:26075576), (PMID:31664108)		 MGI PMID:10570150 PMID:26075576 PMID:31664108 NCBI chr 6:108,190,044...108,528,077
Ensembl chr 6:108,190,057...108,528,070 		JBrowse link
G Jak2 Janus kinase 2 involved_in ISO in response to human growth hormone RGD
MGI		 PMID:16597920 GO_REF:0000096 MGI:4417868 RGD:1641815 NCBI chr19:29,229,006...29,290,495
Ensembl chr19:29,229,228...29,290,480 		JBrowse link
G Mcu mitochondrial calcium uniporter involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:59,282,806...59,453,231
Ensembl chr10:59,282,806...59,452,514 		JBrowse link
G Myrip myosin VIIA and Rab interacting protein involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:120,132,996...120,305,167
Ensembl chr 9:120,130,579...120,303,907 		JBrowse link
G Nkx6-1 NK6 homeobox 1 involved_in ISO RGD
MGI		 PMID:15883383 GO_REF:0000096 MGI:4417868 RGD:2306242 NCBI chr 5:101,807,050...101,812,577
Ensembl chr 5:101,806,005...101,812,862 		JBrowse link
G Nlgn2 neuroligin 2 involved_in ISO RGD
MGI		 PMID:18755801 PMID:22528485 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 RGD:2314456 RGD:9743981 NCBI chr11:69,713,949...69,728,610
Ensembl chr11:69,713,948...69,728,610 		JBrowse link
G Nnat neuronatin involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:15793245) GO_Central
MGI		 PMID:15793245 GO_REF:0000033 NCBI chr 2:157,401,936...157,404,445
Ensembl chr 2:157,401,998...157,404,442 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 involved_in ISO RGD
MGI		 PMID:17259388 GO_REF:0000096 MGI:4417868 RGD:2311606 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847 		JBrowse link
G Oga O-GlcNAcase involved_in ISO RGD
MGI		 PMID:17095531 GO_REF:0000096 MGI:4417868 RGD:2305956 NCBI chr19:45,738,698...45,772,274
Ensembl chr19:45,738,698...45,772,276 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 involved_in ISO
IMP		 (PMID:26494622)
(PMID:31664108)		 MGI PMID:26494622 PMID:31664108 NCBI chr 5:123,153,078...123,168,515
Ensembl chr 5:123,153,137...123,168,519 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) involved_in ISO RGD
MGI		 PMID:19635791 GO_REF:0000096 MGI:4417868 RGD:7242950 NCBI chr14:55,777,721...55,787,477
Ensembl chr14:55,777,723...55,788,699 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 involved_in ISO
IDA		 (MGI:2388494|PMID:12219087) RGD
UniProt
MGI		 PMID:12219087 PMID:18439098 GO_REF:0000096 MGI:2388494 MGI:4417868 RGD:2306975 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 involved_in ISO RGD
MGI		 PMID:16980436 GO_REF:0000096 MGI:4417868 RGD:2304071 NCBI chr 1:130,616,780...130,656,990
Ensembl chr 1:130,616,919...130,656,990
Ensembl chr 1:130,616,919...130,656,990 		JBrowse link
G Pfkm phosphofructokinase, muscle acts_upstream_of_or_within IMP (PMID:17595219) MGI PMID:17595219 NCBI chr15:97,990,470...98,030,328
Ensembl chr15:97,990,470...98,030,332 		JBrowse link
G Plcb1 phospholipase C, beta 1 involved_in IMP
IGI		 (PMID:31268747)
(PMID:26075576)
(PMID:10570150)		 MGI PMID:10570150 PMID:26075576 PMID:31268747 NCBI chr 2:134,628,084...135,317,178
Ensembl chr 2:134,627,987...135,317,178 		JBrowse link
G Prkaca protein kinase, cAMP dependent, catalytic, alpha involved_in IMP
IDA		 (PMID:9075801)
(PMID:23349500), (PMID:25475437)		 MGI PMID:9075801 PMID:23349500 PMID:25475437 NCBI chr 8:84,699,607...84,723,073
Ensembl chr 8:84,699,622...84,723,072 		JBrowse link
G Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha involved_in IMP (PMID:9075801) MGI PMID:9075801 NCBI chr11:109,539,849...109,560,489
Ensembl chr11:109,540,231...109,560,482 		JBrowse link
G Prkcb protein kinase C, beta involved_in IDA (PMID:27226533) MGI PMID:27226533 NCBI chr 7:121,888,327...122,233,625
Ensembl chr 7:121,887,974...122,233,625 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within IMP (PMID:12837755) MGI PMID:12837755 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Psmd9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 involved_in ISS
ISO		 (MGI:3790268|PMID:10567574) BHF-UCL
MGI		 PMID:10567574 GO_REF:0000096 MGI:3790268 MGI:4417868 NCBI chr 5:123,366,253...123,388,189
Ensembl chr 5:123,307,476...123,388,194 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 involved_in ISO RGD
MGI		 PMID:15039777 GO_REF:0000096 MGI:4417868 RGD:10045958 NCBI chr10:79,690,502...79,700,269
Ensembl chr10:79,690,261...79,700,605 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor (GEF) 4 involved_in IMP (PMID:11598134) MGI PMID:11598134 NCBI chr 2:71,811,559...72,087,818
Ensembl chr 2:71,811,584...72,087,818 		JBrowse link
G Rbp4 retinol binding protein 4, plasma involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729 		JBrowse link
G Rph3al rabphilin 3A-like (without C2 domains) involved_in IDA (MGI:3044444|PMID:15159548) UniProt PMID:15159548 MGI:3044444 NCBI chr11:75,721,818...75,858,440
Ensembl chr11:75,721,825...75,829,255 		JBrowse link
G Serp1 stress-associated endoplasmic reticulum protein 1 acts_upstream_of_or_within IMP (PMID:16415102) MGI PMID:16415102 NCBI chr 3:58,429,390...58,433,305
Ensembl chr 3:58,427,238...58,433,313 		JBrowse link
G Sirt3 sirtuin 3 involved_in ISO RGD
MGI		 PMID:23397292 GO_REF:0000096 MGI:4417868 RGD:9586042 NCBI chr 7:140,443,576...140,462,222
Ensembl chr 7:140,443,579...140,462,222 		JBrowse link
G Sirt6 sirtuin 6 involved_in IDA (MGI:6101624|PMID:27457971) UniProt PMID:27457971 MGI:6101624 NCBI chr10:81,457,621...81,463,631
Ensembl chr10:81,457,619...81,463,631 		JBrowse link
G Slc30a8 solute carrier family 30 (zinc transporter), member 8 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr15:52,158,949...52,199,194
Ensembl chr15:52,158,949...52,199,194 		JBrowse link
G Snap25 synaptosomal-associated protein 25 ISO RGD PMID:15042624 RGD:1581081 NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348 		JBrowse link
G Sox4 SRY (sex determining region Y)-box 4 involved_in IMP (MGI:3819280|PMID:18477811) UniProt PMID:18477811 MGI:3819280 NCBI chr13:29,132,902...29,137,682
Ensembl chr13:29,132,902...29,137,696 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in IMP
IDA		 (PMID:31664108)
(PMID:30131394), (PMID:31664108)
(PMID:18452988)		 MGI PMID:18452988 PMID:30131394 PMID:31664108 NCBI chr 7:101,909,279...102,086,525
Ensembl chr 7:101,917,013...102,086,526 		JBrowse link
G Tardbp TAR DNA binding protein involved_in ISO RGD
MGI		 PMID:21127054 GO_REF:0000096 MGI:4417868 RGD:7243008 NCBI chr 4:148,696,839...148,711,672
Ensembl chr 4:148,696,839...148,711,476 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box involved_in IMP
ISO		 (MGI:4412432|PMID:19168596) BHF-UCL
MGI		 PMID:19168596 GO_REF:0000119 MGI:4412432 MGI:4834177 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Tm7sf3 transmembrane 7 superfamily member 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:146,503,774...146,536,103
Ensembl chr 6:146,503,850...146,544,322 		JBrowse link
G Trh thyrotropin releasing hormone involved_in ISO
IBA		 RGD
GO_Central
MGI		 PMID:16118471 GO_REF:0000033 GO_REF:0000096 MGI:4417868 RGD:1600419 NCBI chr 6:92,219,042...92,221,631
Ensembl chr 6:92,219,042...92,221,631 		JBrowse link
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 involved_in ISO (PMID:26494622) MGI PMID:26494622 NCBI chr 9:95,587,125...95,632,438
Ensembl chr 9:95,587,135...95,632,428 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 involved_in ISO RGD
MGI		 PMID:16601673 GO_REF:0000096 MGI:4417868 RGD:9999436 NCBI chr10:77,743,556...77,805,746
Ensembl chr10:77,743,556...77,806,397 		JBrowse link
G Ucn3 urocortin 3 involved_in ISO RGD
MGI		 PMID:17360501 GO_REF:0000096 MGI:4417868 RGD:2306172 NCBI chr13:3,990,688...3,995,349
Ensembl chr13:3,990,688...3,995,349 		JBrowse link
positive regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP-binding cassette, sub-family C member 8 involved_in IMP (PMID:16924481) MGI PMID:16924481 NCBI chr 7:45,753,952...45,829,441
Ensembl chr 7:45,753,947...45,829,457 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO RGD
MGI		 PMID:29540530 GO_REF:0000096 MGI:4417868 RGD:41404656 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962 		JBrowse link
G Adcy8 adenylate cyclase 8 involved_in IMP
ISO		 (MGI:5636119|PMID:25403481) UniProt
MGI		 PMID:25403481 GO_REF:0000096 MGI:4417868 MGI:5636119 NCBI chr15:64,570,884...64,794,145
Ensembl chr15:64,568,933...64,794,145 		JBrowse link
G Ano1 anoctamin 1, calcium activated chloride channel involved_in IMP
ISO		 (MGI:5640937|PMID:24885604) UniProt
MGI		 PMID:24885604 GO_REF:0000119 MGI:4834177 MGI:5640937 NCBI chr 7:144,142,286...144,305,762
Ensembl chr 7:144,142,286...144,305,711 		JBrowse link
G Arrb1 arrestin, beta 1 involved_in IMP (MGI:4453294|PMID:19915011) UniProt PMID:19915011 MGI:4453294 NCBI chr 7:99,184,356...99,255,979
Ensembl chr 7:99,184,673...99,255,978 		JBrowse link
G Atg7 autophagy related 7 acts_upstream_of_or_within IMP (PMID:24105478) MGI PMID:24105478 NCBI chr 6:114,620,075...114,837,565
Ensembl chr 6:114,620,058...114,837,575 		JBrowse link
G Bad BCL2-associated agonist of cell death involved_in IMP (MGI:3778846|PMID:18223655) UniProt PMID:18223655 MGI:3778846 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Baiap3 BAI1-associated protein 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:25,461,633...25,475,255
Ensembl chr17:25,461,633...25,475,338 		JBrowse link
G C1qtnf12 C1q and tumor necrosis factor related 12 acts_upstream_of_or_within IDA (PMID:22275362) MGI PMID:22275362 NCBI chr 4:156,046,769...156,051,086
Ensembl chr 4:156,046,775...156,051,086 		JBrowse link
G C2cd2l C2 calcium-dependent domain containing 2-like involved_in
acts_upstream_of_or_within		 ISO
IMP
IBA		 (PMID:24012759) MGI
GO_Central		 PMID:24012759 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 9:44,220,534...44,231,579
Ensembl chr 9:44,220,534...44,231,582 		JBrowse link
G Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit involved_in ISO RGD
MGI		 PMID:23229155 GO_REF:0000096 MGI:4417868 RGD:13506727 NCBI chr14:29,761,898...30,213,113
Ensembl chr14:29,761,896...30,213,412 		JBrowse link
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 involved_in ISO RGD
MGI		 PMID:31327268 GO_REF:0000096 MGI:4417868 RGD:18899561 NCBI chr 4:138,182,459...138,187,437
Ensembl chr 4:138,181,625...138,187,434 		JBrowse link
G Cftr cystic fibrosis transmembrane conductance regulator involved_in IMP
ISO		 (MGI:5640937|PMID:24885604) UniProt
MGI		 PMID:24885604 GO_REF:0000119 MGI:4834177 MGI:5640937 NCBI chr 6:18,170,686...18,322,769
Ensembl chr 6:18,170,686...18,322,767 		JBrowse link
G Crh corticotropin releasing hormone involved_in ISO RGD
MGI		 PMID:20080775 GO_REF:0000096 MGI:4417868 RGD:5508172 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 involved_in ISO RGD
MGI		 PMID:17130471 GO_REF:0000096 MGI:4417868 RGD:1642149 NCBI chr 5:115,435,129...115,438,995
Ensembl chr 5:115,435,169...115,439,058 		JBrowse link
G Fto FTO alpha-ketoglutarate dependent dioxygenase involved_in ISO RGD
MGI		 PMID:29890211 GO_REF:0000096 MGI:4417868 RGD:329951007 NCBI chr 8:92,039,995...92,395,061
Ensembl chr 8:92,040,153...92,395,067 		JBrowse link
G Gcg glucagon involved_in IDA
IBA		 (MGI:4453294|PMID:19915011) UniProt
GO_Central		 PMID:19915011 GO_REF:0000033 MGI:4453294 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994 		JBrowse link
G Ghrl ghrelin involved_in ISO RGD
MGI		 PMID:16647196 GO_REF:0000096 MGI:4417868 RGD:12905046 NCBI chr 6:113,693,080...113,696,872
Ensembl chr 6:113,693,080...113,696,841 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 involved_in IDA (MGI:5448527|PMID:20153004) UniProt PMID:20153004 MGI:5448527 NCBI chr13:25,127,135...25,175,919
Ensembl chr13:25,127,135...25,176,484 		JBrowse link
G Gpr27 G protein-coupled receptor 27 acts_upstream_of_or_within IMP (PMID:22253604) MGI PMID:22253604 NCBI chr 6:99,669,328...99,672,027
Ensembl chr 6:99,669,640...99,672,027 		JBrowse link
G Gpr39 G protein-coupled receptor 39 acts_upstream_of_or_within IMP (PMID:19213833) MGI PMID:19213833 NCBI chr 1:125,604,725...125,804,132
Ensembl chr 1:125,604,732...125,801,599 		JBrowse link
G Gpr68 G protein-coupled receptor 68 acts_upstream_of_or_within IMP (PMID:22733973) MGI PMID:22733973 NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457 		JBrowse link
G H2-Eb1 histocompatibility 2, class II antigen E beta involved_in ISO (PMID:21484216) UniProt PMID:21484216 NCBI chr17:34,524,841...34,535,648
Ensembl chr17:34,524,841...34,535,648 		JBrowse link
G Hcfc1 host cell factor C1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr  X:72,986,400...73,011,430
Ensembl chr  X:72,986,398...73,009,963 		JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit acts_upstream_of_or_within IMP (PMID:20440072) MGI PMID:20440072 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304 		JBrowse link
G Kif5b kinesin family member 5B involved_in ISO RGD
MGI		 PMID:25462067 GO_REF:0000096 MGI:4417868 RGD:11059539 NCBI chr18:6,201,005...6,241,524
Ensembl chr18:6,201,002...6,242,174 		JBrowse link
G Lepr leptin receptor involved_in ISO RGD
MGI		 PMID:9751766 GO_REF:0000096 MGI:4417868 RGD:10412039 NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549 		JBrowse link
G Lrp1 low density lipoprotein receptor-related protein 1 involved_in ISO RGD
MGI		 PMID:24865476 GO_REF:0000096 MGI:4417868 RGD:13800516 NCBI chr10:127,374,026...127,457,158
Ensembl chr10:127,374,030...127,457,017 		JBrowse link
G Mpc2 mitochondrial pyruvate carrier 2 acts_upstream_of_or_within IMP (PMID:24910426) MGI PMID:24910426 NCBI chr 1:165,288,829...165,308,787
Ensembl chr 1:165,288,206...165,308,783 		JBrowse link
G Myh9 myosin, heavy polypeptide 9, non-muscle involved_in ISO RGD
MGI		 PMID:23354122 GO_REF:0000096 MGI:4417868 RGD:12798521 NCBI chr15:77,644,788...77,726,315
Ensembl chr15:77,644,787...77,726,375 		JBrowse link
G Nadk NAD kinase involved_in ISO RGD
MGI		 PMID:22550069 GO_REF:0000096 MGI:4417868 RGD:13703105 NCBI chr 4:155,646,838...155,675,458
Ensembl chr 4:155,646,835...155,675,458 		JBrowse link
G Ncoa6 nuclear receptor coactivator 6 involved_in ISO RGD
MGI		 PMID:16738321 GO_REF:0000096 MGI:4417868 RGD:9590126 NCBI chr 2:155,232,585...155,315,741
Ensembl chr 2:155,232,576...155,315,814 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in IMP (MGI:4457989|PMID:20447400) UniProt PMID:20447400 MGI:4457989 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Osbp oxysterol binding protein involved_in ISO RGD
MGI		 PMID:29540530 GO_REF:0000096 MGI:4417868 RGD:41404656 NCBI chr19:11,943,208...11,971,478
Ensembl chr19:11,943,305...11,971,476 		JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 involved_in ISO RGD
MGI		 PMID:20460097 GO_REF:0000096 MGI:4417868 RGD:2326185 NCBI chr15:4,055,910...4,184,826
Ensembl chr15:4,055,865...4,184,826 		JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within IMP (PMID:22253604) MGI PMID:22253604 NCBI chr 5:147,206,907...147,212,658
Ensembl chr 5:147,206,769...147,212,658 		JBrowse link
G Pla2g6 phospholipase A2, group VI involved_in IMP
ISO		 (MGI:3778607|PMID:17895289) UniProt
MGI
RGD		 PMID:11278673 PMID:17895289 GO_REF:0000096 MGI:3778607 MGI:4417868 RGD:6482760 NCBI chr15:79,170,428...79,212,915
Ensembl chr15:79,170,428...79,212,590 		JBrowse link
G Ppard peroxisome proliferator activator receptor delta involved_in ISO RGD
MGI		 PMID:19965574 GO_REF:0000096 MGI:4417868 RGD:2324877 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform involved_in IMP
ISO		 (MGI:5306323|PMID:11978799) UniProt
MGI		 PMID:11978799 GO_REF:0000096 MGI:4417868 MGI:5306323 NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO RGD
MGI		 PMID:24096089 GO_REF:0000096 MGI:4417868 RGD:10413842 NCBI chr17:11,059,227...12,282,257
Ensembl chr17:11,059,271...12,282,248 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IMP
ISO		 (MGI:5489045|PMID:23412604) CACAO
MGI
RGD		 PMID:23412604 GO_REF:0000096 MGI:4417868 MGI:5489045 RGD:14392803 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:51,553,856...51,606,525
Ensembl chr10:51,553,852...51,606,528 		JBrowse link
G Sirt1 sirtuin 1 involved_in ISO RGD
MGI		 PMID:16366736 GO_REF:0000096 MGI:4417868 RGD:9585658 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483 		JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 involved_in IMP (PMID:10823833), (PMID:10969832) MGI PMID:10823833 PMID:10969832 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508 		JBrowse link
G Sri sorcin involved_in IMP (MGI:5487506|PMID:22338092) BHF-UCL PMID:22338092 MGI:5487506 NCBI chr 5:8,096,078...8,119,314
Ensembl chr 5:8,096,078...8,119,379 		JBrowse link
G Stx4a syntaxin 4A (placental) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:127,439,832...127,450,160
Ensembl chr 7:127,423,466...127,448,191 		JBrowse link
G Sybu syntabulin (syntaxin-interacting) involved_in ISO RGD
MGI		 PMID:22975310 GO_REF:0000096 MGI:4417868 RGD:8554225 NCBI chr15:44,535,252...44,651,466
Ensembl chr15:44,535,252...44,651,459 		JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 involved_in ISO RGD
MGI		 PMID:22701540 GO_REF:0000096 MGI:4417868 RGD:10043784 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 involved_in ISO RGD
MGI		 PMID:16806463 GO_REF:0000096 MGI:4417868 RGD:10003029 NCBI chr 7:44,952,579...44,983,495
Ensembl chr 7:44,952,056...44,983,204 		JBrowse link
G Tunar Tcl1 upstream neural differentiation associated RNA involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr12:105,303,087...105,350,191
Ensembl chr12:105,300,129...105,350,191 		JBrowse link
G Vsnl1 visinin-like 1 acts_upstream_of_or_within IDA (PMID:16731532) MGI PMID:16731532 NCBI chr12:11,375,258...11,486,579
Ensembl chr12:11,375,243...11,486,614 		JBrowse link
regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase involved_in IMP (MGI:3803402|PMID:18421434) UniProt PMID:18421434 MGI:3803402 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 involved_in IMP (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333 		JBrowse link
G Cartpt CART prepropeptide involved_in ISO RGD
MGI		 PMID:16443761 GO_REF:0000096 MGI:4417868 RGD:2313632 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344 		JBrowse link
G Cela2a chymotrypsin-like elastase family, member 2A involved_in ISO (PMID:31358993) UniProt PMID:31358993 NCBI chr 4:141,542,265...141,553,316
Ensembl chr 4:141,542,273...141,553,471 		JBrowse link
G Clock clock circadian regulator involved_in IMP (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639 		JBrowse link
G Cnr1 cannabinoid receptor 1 involved_in ISO RGD
MGI		 PMID:19644453 GO_REF:0000096 MGI:4417868 RGD:2314628 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver involved_in ISO RGD
MGI		 PMID:11988095 GO_REF:0000096 MGI:4417868 RGD:1298597 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733 		JBrowse link
G Eipr1 EARP complex and GARP complex interacting protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr12:28,801,802...28,917,493
Ensembl chr12:28,801,802...28,919,864 		JBrowse link
G Ensa endosulfine alpha acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 3:95,532,291...95,539,428
Ensembl chr 3:95,532,304...95,539,413 		JBrowse link
G G6pc2 glucose-6-phosphatase, catalytic, 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:69,041,417...69,058,337
Ensembl chr 2:69,041,417...69,058,185 		JBrowse link
G Gcg glucagon involved_in
acts_upstream_of_or_within		 IDA (MGI:5304221|PMID:22037645)
(PMID:14736883)		 UniProt
MGI		 PMID:14736883 PMID:22037645 MGI:5304221 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994 		JBrowse link
G Gck glucokinase involved_in
acts_upstream_of_or_within		 ISO
IBA
IMP		 (PMID:8530440), (PMID:8954920) MGI
GO_Central		 PMID:8530440 PMID:8954920 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081 		JBrowse link
G Gip gastric inhibitory polypeptide involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:95,915,358...95,921,657
Ensembl chr11:95,915,371...95,921,657 		JBrowse link
G Hadh hydroxyacyl-Coenzyme A dehydrogenase involved_in IMP (MGI:4849622|PMID:20670938) UniProt PMID:20670938 MGI:4849622 NCBI chr 3:131,027,068...131,065,750
Ensembl chr 3:131,027,068...131,065,750 		JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha involved_in IMP (MGI:3575336|PMID:15761495) BHF-UCL PMID:15761495 MGI:3575336 NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830 		JBrowse link
G Ifng interferon gamma involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059 		JBrowse link
G Il6 interleukin 6 involved_in IDA
ISO		 (MGI:5304221|PMID:22037645) UniProt
MGI		 PMID:22037645 GO_REF:0000119 MGI:4834177 MGI:5304221 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 7:45,746,545...45,750,215
Ensembl chr 7:45,743,377...45,750,188 		JBrowse link
G Lep leptin acts_upstream_of_or_within IMP (PMID:16513828) MGI PMID:16513828 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876 		JBrowse link
G Mtnr1b melatonin receptor 1B involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:15,773,910...15,785,852
Ensembl chr 9:15,735,824...15,785,852 		JBrowse link
G Nos2 nitric oxide synthase 2, inducible involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080 		JBrowse link
G Pde3b phosphodiesterase 3B, cGMP-inhibited acts_upstream_of_or_within IDA (PMID:14736883) MGI PMID:14736883 NCBI chr 7:114,014,388...114,137,173
Ensembl chr 7:114,014,516...114,138,486 		JBrowse link
G Per2 period circadian clock 2 involved_in IMP (MGI:5319572|PMID:22504074) UniProt PMID:22504074 MGI:5319572 NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046 		JBrowse link
G Pick1 protein interacting with C kinase 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:79,113,373...79,133,666
Ensembl chr15:79,113,373...79,133,684 		JBrowse link
G Ppard peroxisome proliferator activator receptor delta involved_in NAS (MGI:3688371|PMID:14676330) UniProt PMID:14676330 MGI:3688371 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448 		JBrowse link
G Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr14:20,549,432...20,596,641
Ensembl chr14:20,549,432...20,596,641 		JBrowse link
G Rfx3 regulatory factor X, 3 (influences HLA class II expression) involved_in IMP (MGI:3713191|PMID:17229940), (MGI:4941444|PMID:20413507) UniProt PMID:17229940 PMID:20413507 MGI:3713191 MGI:4941444 NCBI chr19:27,739,121...27,995,287
Ensembl chr19:27,739,121...27,988,566 		JBrowse link
G Rfx6 regulatory factor X, 6 involved_in IMP
ISO		 (MGI:4422104|PMID:20148032) UniProt
MGI		 PMID:20148032 GO_REF:0000119 MGI:4422104 MGI:4834177 NCBI chr10:51,553,856...51,606,525
Ensembl chr10:51,553,852...51,606,528 		JBrowse link
G Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 involved_in IMP (MGI:5465432|PMID:22522610) UniProt PMID:22522610 MGI:5465432 NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778 		JBrowse link
G Slc25a22 solute carrier family 25 (mitochondrial carrier, glutamate), member 22 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 7:141,009,662...141,017,787
Ensembl chr 7:141,009,657...141,017,805 		JBrowse link
G Slc8b1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:120,649,233...120,672,089
Ensembl chr 5:120,649,233...120,672,089 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 acts_upstream_of_or_within IMP (PMID:18178930) MGI PMID:18178930 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407 		JBrowse link
G Sstr5 somatostatin receptor 5 acts_upstream_of_or_within
involved_in		 IMP
IBA		 (PMID:15919085) MGI
GO_Central		 PMID:15919085 GO_REF:0000033 NCBI chr17:25,708,849...25,716,262
Ensembl chr17:25,708,847...25,733,577 		JBrowse link
G Syt7 synaptotagmin VII involved_in IMP
ISO		 (MGI:3773625|PMID:18308938) UniProt
MGI
RGD		 PMID:17709608 PMID:18308938 GO_REF:0000096 MGI:3773625 MGI:4417868 RGD:2311143 NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544 		JBrowse link
G Syt9 synaptotagmin IX involved_in ISO RGD
MGI		 PMID:16165130 GO_REF:0000096 MGI:4417868 RGD:2311147 NCBI chr 7:106,969,929...107,147,863
Ensembl chr 7:106,969,935...107,147,863 		JBrowse link
G Tcirg1 T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 acts_upstream_of_or_within IMP (PMID:17046993) MGI PMID:17046993 NCBI chr19:3,946,050...3,957,717
Ensembl chr19:3,946,050...3,957,133 		JBrowse link
G Tfap2b transcription factor AP-2 beta involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:19,279,132...19,309,071
Ensembl chr 1:19,279,138...19,308,800 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983 		JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 involved_in IMP (MGI:5520038|PMID:22363741) UniProt PMID:22363741 MGI:5520038 NCBI chr17:27,341,639...27,352,865
Ensembl chr17:27,341,637...27,352,890 		JBrowse link
regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP-binding cassette, sub-family A member 12 involved_in IMP (MGI:6394227|PMID:32072744) UniProt PMID:32072744 MGI:6394227 NCBI chr 1:71,282,249...71,454,069
Ensembl chr 1:71,281,435...71,454,069 		JBrowse link
G Adcy5 adenylate cyclase 5 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:34,974,933...35,126,108
Ensembl chr16:34,975,247...35,126,108 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 acts_upstream_of_or_within IMP (PMID:19644667) MGI PMID:19644667 NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569 		JBrowse link
G Brsk2 BR serine/threonine kinase 2 involved_in IMP
ISO		 (MGI:5448801|PMID:22798068) UniProt
MGI		 PMID:22798068 GO_REF:0000119 MGI:4834177 MGI:5448801 NCBI chr 7:141,503,488...141,557,981
Ensembl chr 7:141,503,488...141,557,984 		JBrowse link
G Cacna1e calcium channel, voltage-dependent, R type, alpha 1E subunit acts_upstream_of_or_within IMP (PMID:11923483), (PMID:15630454) MGI PMID:11923483 PMID:15630454 NCBI chr 1:154,266,552...154,760,374
Ensembl chr 1:154,266,477...154,760,247 		JBrowse link
G Cdk16 cyclin dependent kinase 16 involved_in IMP
ISO		 (MGI:5448801|PMID:22798068) UniProt
MGI		 PMID:22798068 GO_REF:0000119 MGI:4834177 MGI:5448801 NCBI chr  X:20,554,210...20,566,119
Ensembl chr  X:20,554,193...20,566,119 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 NOT|involved_in ISO PMID:21494687 ParkinsonsUK-UCL PMID:21494687 RGD:11567254 NCBI chr 2:130,495,955...130,506,549
Ensembl chr 2:130,495,880...130,506,579 		JBrowse link
G Efna5 ephrin A5 involved_in IMP (MGI:5294297|PMID:17448994) UniProt PMID:17448994 MGI:5294297 NCBI chr17:62,909,949...63,188,431
Ensembl chr17:62,911,179...63,188,312 		JBrowse link
G Epha5 Eph receptor A5 involved_in IDA (MGI:5294297|PMID:17448994) UniProt PMID:17448994 MGI:5294297 NCBI chr 5:84,199,024...84,565,677
Ensembl chr 5:84,202,620...84,565,241 		JBrowse link
G Foxa2 forkhead box A2 involved_in IDA (MGI:5142372|PMID:11875061) BHF-UCL PMID:11875061 MGI:5142372 NCBI chr 2:147,884,797...147,888,889
Ensembl chr 2:147,884,797...147,888,889 		JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 acts_upstream_of_or_within IMP (PMID:19651901) MGI PMID:19651901 NCBI chr 9:82,991,995...83,029,411
Ensembl chr 9:82,992,001...83,028,738 		JBrowse link
G Lrp5 low density lipoprotein receptor-related protein 5 acts_upstream_of_or_within IMP (PMID:12509515) MGI PMID:12509515 NCBI chr19:3,634,825...3,736,574
Ensembl chr19:3,634,828...3,736,564 		JBrowse link
G Mir130a microRNA 130a acts_upstream_of_or_within IMP (PMID:20417623) MGI PMID:20417623 NCBI chr 2:84,571,459...84,571,522
Ensembl chr 2:84,571,459...84,571,522 		JBrowse link
G Mir200a microRNA 200a acts_upstream_of_or_within IMP (PMID:20417623) MGI PMID:20417623 NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442 		JBrowse link
G Mir410 microRNA 410 acts_upstream_of_or_within IDA
IMP		 (PMID:20417623) MGI PMID:20417623 NCBI chr12:109,710,149...109,710,229
Ensembl chr12:109,710,149...109,710,229 		JBrowse link
G Myt1 myelin transcription factor 1 acts_upstream_of_or_within IMP (PMID:17928203) MGI PMID:17928203 NCBI chr 2:181,405,099...181,469,579
Ensembl chr 2:181,405,125...181,469,590 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 involved_in IMP (MGI:5313784|PMID:22166979) UniProt PMID:22166979 MGI:5313784 NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447 		JBrowse link
G Piwil4 piwi-like RNA-mediated gene silencing 4 involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 9:14,613,072...14,651,968
Ensembl chr 9:14,607,526...14,652,036 		JBrowse link
G Prkce protein kinase C, epsilon acts_upstream_of_or_within IMP (PMID:19401415) MGI PMID:19401415 NCBI chr17:86,472,631...86,965,347
Ensembl chr17:86,475,213...86,965,347 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 acts_upstream_of_or_within IMP (PMID:23776622) MGI PMID:23776622 NCBI chr 9:45,849,155...45,869,299
Ensembl chr 9:45,849,155...45,866,556 		JBrowse link
G Slc9b2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 involved_in IDA (MGI:5492253|PMID:23720317) UniProt PMID:23720317 MGI:5492253 NCBI chr 3:135,013,083...135,048,606
Ensembl chr 3:135,013,461...135,051,148 		JBrowse link
G Stxbp4 syntaxin binding protein 4 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr11:90,367,318...90,528,962
Ensembl chr11:90,367,318...90,528,910 		JBrowse link
G Sybu syntabulin (syntaxin-interacting) acts_upstream_of_or_within ISO (PMID:22975310) MGI PMID:22975310 NCBI chr15:44,535,252...44,651,466
Ensembl chr15:44,535,252...44,651,459 		JBrowse link
G Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box acts_upstream_of_or_within IMP
ISO		 (PMID:19168596) MGI PMID:19168596 GO_REF:0000008 NCBI chr19:55,730,227...55,922,091
Ensembl chr19:55,730,252...55,922,086 		JBrowse link
G Tiam1 T cell lymphoma invasion and metastasis 1 involved_in ISO RGD
MGI		 PMID:18930714 GO_REF:0000096 MGI:4417868 RGD:10043296 NCBI chr16:89,583,999...89,942,488
Ensembl chr16:89,583,999...89,940,657 		JBrowse link
G Ufm1 ubiquitin-fold modifier 1 NOT|involved_in ISO PMID:21494687 ParkinsonsUK-UCL PMID:21494687 RGD:11567254 NCBI chr 3:53,760,797...53,771,228
Ensembl chr 3:53,760,797...53,771,251 		JBrowse link
G Zbed6 zinc finger, BED type containing 6 involved_in IMP (MGI:6120647|PMID:29440408) UniProt PMID:29440408 MGI:6120647 NCBI chr 1:133,547,606...133,589,112
Ensembl chr 1:133,547,678...133,589,056 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    cellular process 17593
      export from cell 1113
        secretion by cell 1025
          protein secretion 464
            insulin secretion 274
              insulin secretion involved in cellular response to glucose stimulus + 105
              negative regulation of insulin secretion + 63
              positive regulation of insulin secretion + 120
              regulation of insulin secretion + 231
Path 2
Term Annotations click to browse term
  biological_process 28573
    localization 5524
      establishment of localization 4823
        transport 4507
          nitrogen compound transport 2022
            amide transport 408
              peptide transport 356
                peptide secretion 348
                  peptide hormone secretion 340
                    insulin secretion 274
                      insulin secretion involved in cellular response to glucose stimulus + 105
                      negative regulation of insulin secretion + 63
                      positive regulation of insulin secretion + 120
                      regulation of insulin secretion + 231
paths to the root