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ONTOLOGY REPORT - ANNOTATIONS

Term:insulin secretion
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Accession:GO:0030073 term browser browse the term
Definition:The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects.
Synonyms:only_in_taxon: NCBITaxon:6072 ! Eumetazoa


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insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1C activin A receptor type 1C involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18480258) Ensembl
MGI		 PMID:18480258 GO_REF:0000107 NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151 		JBrowse link
G ACVR2B activin A receptor type 2B acts_upstream_of_or_within ISO (PMID:17849440) MGI PMID:17849440 NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063 		JBrowse link
G ADCYAP1 adenylate cyclase activating polypeptide 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749 		JBrowse link
G ANXA1 annexin A1 involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:12459455 GO_REF:0000118 RGD:628365 NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779 		JBrowse link
G ANXA7 annexin A7 acts_upstream_of ISO (PMID:20440069) MGI PMID:20440069 NCBI chr10:69,923,353...69,962,980
Ensembl chr10:72,381,447...72,420,749 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C acts_upstream_of_or_within ISO (PMID:12881419) MGI PMID:12881419 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G CCKAR cholecystokinin A receptor ISO RGD PMID:9773935 RGD:2313338 NCBI chr 4:20,881,340...20,890,986
Ensembl chr 4:26,157,702...26,166,773 		JBrowse link
G CPLX1 complexin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:889,037...930,046
Ensembl chr 4:819,833...858,953 		JBrowse link
G CPLX3 complexin 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:53,769,138...53,774,330
Ensembl chr15:73,386,826...73,391,991 		JBrowse link
G DGAT1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:12193544 RGD:628375 NCBI chr 8:141,079,948...141,090,619
Ensembl chr 8:144,064,587...144,080,155 		JBrowse link
G FAM3B FAM3 metabolism regulating signaling molecule B involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:27,650,185...27,692,249
Ensembl chr21:40,979,149...41,020,089 		JBrowse link
G FFAR1 free fatty acid receptor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17395749) Ensembl
MGI		 PMID:17395749 GO_REF:0000107 NCBI chr19:32,298,259...32,300,601
Ensembl chr19:41,034,905...41,035,807 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18466757) Ensembl
MGI		 PMID:18466757 GO_REF:0000107 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082 		JBrowse link
G GLP1R glucagon like peptide 1 receptor involved_in ISO PMID:10362617 UniProt PMID:10362617 RGD:8553736 NCBI chr 6:38,637,838...38,680,423
Ensembl chr 6:39,823,373...39,855,784 		JBrowse link
G GPR119 G protein-coupled receptor 119 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15607732) Ensembl
MGI		 PMID:15607732 GO_REF:0000107 NCBI chr  X:119,511,372...119,512,611
Ensembl chr  X:129,803,383...129,804,390 		JBrowse link
G GPR68 G protein-coupled receptor 68 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:22733973) Ensembl
MGI		 PMID:22733973 GO_REF:0000107 NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806 		JBrowse link
G HMGA1 high mobility group AT-hook 1 acts_upstream_of_or_within ISO (PMID:15924147) MGI PMID:15924147 NCBI chr 6:33,807,171...33,816,603 JBrowse link
G HNF1A HNF1 homeobox A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9566924), (PMID:9733737)
(PMID:15142986), (PMID:9593777)		 Ensembl
MGI
InterPro		 PMID:9566924 PMID:9593777 PMID:9733737 PMID:15142986 GO_REF:0000002 GO_REF:0000107 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
G HNF1B HNF1 homeobox B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15142986) InterPro
MGI
Ensembl		 PMID:15142986 GO_REF:0000002 GO_REF:0000107 NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863 		JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (PMID:10078572) MGI PMID:10078572 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730 		JBrowse link
G IL1RN interleukin 1 receptor antagonist involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12975454) Ensembl
MGI		 PMID:12975454 GO_REF:0000107 NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839 		JBrowse link
G ILDR2 immunoglobulin like domain containing receptor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18654634) Ensembl
MGI		 PMID:18654634 GO_REF:0000107 NCBI chr 1:142,315,984...142,395,729
Ensembl chr 1:146,125,919...146,181,822 		JBrowse link
G IRS1 insulin receptor substrate 1 NOT|acts_upstream_of_or_within ISO (PMID:9062343) MGI PMID:9062343 NCBI chr2B:113,973,191...114,041,127
Ensembl chr2B:232,849,239...232,852,967 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16141392) Ensembl
MGI		 PMID:16141392 GO_REF:0000107 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G LOC100977566 cytochrome b5 reductase 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15247412) Ensembl
MGI		 PMID:15247412 GO_REF:0000107 NCBI chr 6:81,756,292...81,864,365
Ensembl chr 6:85,030,058...85,130,948 		JBrowse link
G LOC103782656 G-protein coupled receptor 39 acts_upstream_of ISO (PMID:19213841) MGI PMID:19213841 NCBI chr2B:27,429,851...27,431,292 JBrowse link
G MAFA MAF bZIP transcription factor A acts_upstream_of ISO (PMID:17941991) BHF-UCL PMID:17941991 NCBI chr 8:140,178,322...140,181,152 JBrowse link
G MC4R melanocortin 4 receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16141392) Ensembl
MGI		 PMID:16141392 GO_REF:0000107 NCBI chr18:53,744,172...53,747,282
Ensembl chr18:57,069,259...57,070,257 		JBrowse link
G MYO5A myosin VA acts_upstream_of_or_within ISO (PMID:15788565) MGI PMID:15788565 NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319 		JBrowse link
G NEUROD1 neuronal differentiation 1 acts_upstream_of ISO (PMID:17941991) BHF-UCL PMID:17941991 NCBI chr2B:68,939,341...68,943,516 JBrowse link
G NNAT neuronatin acts_upstream_of ISO (PMID:15793245) MGI PMID:15793245 NCBI chr20:33,842,071...33,845,575
Ensembl chr20:34,955,234...34,959,493 		JBrowse link
G PARK7 Parkinsonism associated deglycase involved_in ISO (MGI:5908331|PMID:22611253) UniProt PMID:22611253 MGI:5908331 NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271 		JBrowse link
G PCLO piccolo presynaptic cytomatrix protein acts_upstream_of_or_within ISO (PMID:12401793) MGI PMID:12401793 NCBI chr 7:74,714,364...75,126,518 JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of ISO (PMID:17941991) BHF-UCL PMID:17941991 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of		 IEA
ISO		 (PMID:12837755) Ensembl
MGI		 PMID:12837755 GO_REF:0000107 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313 		JBrowse link
G PTPRN protein tyrosine phosphatase receptor type N involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:106,547,156...106,567,056
Ensembl chr2B:225,138,887...225,206,700 		JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768 		JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11598134), (PMID:12401793) Ensembl
MGI		 PMID:11598134 PMID:12401793 GO_REF:0000107 NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644 		JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:11598134) MGI PMID:11598134 NCBI chr 8:100,156,403...100,894,128 JBrowse link
G SERP1 stress associated endoplasmic reticulum protein 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16415102) Ensembl
MGI		 PMID:16415102 GO_REF:0000107 NCBI chr 3:147,559,607...147,564,668
Ensembl chr 3:155,133,115...155,137,241 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 ISO RGD PMID:18577569 RGD:2317338 NCBI chr10:113,823,005...113,862,451
Ensembl chr10:117,250,639...117,290,064 		JBrowse link
G SLC30A8 solute carrier family 30 member 8 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:19479076 GO_REF:0000107 GO_REF:0000118 RGD:2315022 NCBI chr 8:113,624,785...113,851,633
Ensembl chr 8:116,223,595...116,394,095 		JBrowse link
G SMAD2 SMAD family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17849440) Ensembl
MGI		 PMID:17849440 GO_REF:0000107 NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530 		JBrowse link
G SNX19 sorting nexin 19 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24843546) Ensembl
MGI		 PMID:24843546 GO_REF:0000107 NCBI chr11:125,691,537...125,732,206
Ensembl chr11:129,581,876...129,622,517 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16890542) Ensembl
MGI		 PMID:16890542 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G STX1A syntaxin 1A involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:80,852,495...80,862,255 JBrowse link
G STXBP3 syntaxin binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19188424) Ensembl
MGI		 PMID:19188424 GO_REF:0000107 NCBI chr 1:111,120,487...111,185,669
Ensembl chr 1:110,287,374...110,351,616 		JBrowse link
G SYTL4 synaptotagmin like 4 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:16890542) Ensembl
MGI		 PMID:16890542 GO_REF:0000107 NCBI chr  X:89,885,478...89,941,381
Ensembl chr  X:100,024,434...100,051,663 		JBrowse link
G VGF VGF nerve growth factor inducible involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16141392) Ensembl
MGI		 PMID:16141392 GO_REF:0000107 NCBI chr 7:93,302,956...93,307,892 JBrowse link
insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATG7 autophagy related 7 acts_upstream_of ISO (PMID:24105478) MGI PMID:24105478 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398 		JBrowse link
G CCDC186 coiled-coil domain containing 186 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27293546) Ensembl
MGI		 PMID:27293546 GO_REF:0000107 NCBI chr10:110,720,243...110,774,362
Ensembl chr10:114,156,401...114,194,141 		JBrowse link
G CLTRN collectrin, amino acid transport regulator acts_upstream_of_positive_effect
involved_in		 ISO
IEA		 (PMID:16330323) GO_Central
Ensembl		 PMID:16330323 GO_REF:0000107 NCBI chr  X:8,255,666...8,293,354
Ensembl chr  X:15,535,069...15,575,268 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in
acts_upstream_of		 IEA
ISO		 (PMID:19805579) Ensembl
MGI		 PMID:19805579 GO_REF:0000107 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of		 IEA
ISO		 (PMID:20440072) Ensembl
MGI		 PMID:20440072 GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G LOC103782656 G-protein coupled receptor 39 acts_upstream_of ISO (PMID:19213833) MGI PMID:19213833 NCBI chr2B:27,429,851...27,431,292 JBrowse link
G PTPRN protein tyrosine phosphatase receptor type N involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr2B:106,547,156...106,567,056
Ensembl chr2B:225,138,887...225,206,700 		JBrowse link
G PTPRN2 protein tyrosine phosphatase receptor type N2 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:149,158,513...150,390,077
Ensembl chr 7:160,851,703...161,756,325 		JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in ISO (MGI:4352608|PMID:19335615) UniProt PMID:19335615 MGI:4352608 NCBI chr19:7,676,095...7,690,177 JBrowse link
G RAB11FIP2 RAB11 family interacting protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:114,577,851...114,619,808
Ensembl chr10:117,970,693...118,044,607 		JBrowse link
G RAB11FIP5 RAB11 family interacting protein 5 involved_in ISO (MGI:4352608|PMID:19335615) UniProt PMID:19335615 MGI:4352608 NCBI chr2A:73,126,262...73,165,892
Ensembl chr2A:74,620,821...74,657,419 		JBrowse link
G RAF1 Raf-1 proto-oncogene, serine/threonine kinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21817126) Ensembl
MGI		 PMID:21817126 GO_REF:0000107 NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871 		JBrowse link
G RBM4 RNA binding motif protein 4 acts_upstream_of_or_within ISO (PMID:23129807) MGI PMID:23129807 NCBI chr11:61,996,221...62,026,007
Ensembl chr11:65,298,404...65,349,183 		JBrowse link
G SELENOT selenoprotein T involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23913443) Ensembl
MGI		 PMID:23913443 GO_REF:0000107 NCBI chr 3:147,620,862...147,648,039
Ensembl chr 3:155,194,428...155,221,578 		JBrowse link
negative regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15163199 GO_REF:0000107 RGD:1598646 NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870 		JBrowse link
G ACVR1C activin A receptor type 1C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18480258) Ensembl
MGI		 PMID:18480258 GO_REF:0000107 NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:10952463)
(PMID:17992256), (PMID:1898674)
(PMID:1898674)		 BHF-UCL
MGI		 PMID:1898674 PMID:10952463 PMID:17992256 NCBI chr10:107,669,860...107,673,685 JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:116,105,935...116,114,241
Ensembl chr 8:118,855,445...118,865,039 		JBrowse link
G CHGA chromogranin A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr14:73,555,834...73,568,547
Ensembl chr14:92,895,450...92,908,159 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18216393 RGD:2311570 NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107
G FAM3D FAM3 metabolism regulating signaling molecule D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:58,564,083...58,685,370
Ensembl chr 3:59,973,612...59,993,727 		JBrowse link
G FBN1 fibrillin 1 involved_in ISO (MGI:6442875|PMID:30997682) UniProt PMID:30997682 MGI:6442875 NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,394,401...32,398,730
Ensembl chr19:41,132,599...41,133,591 		JBrowse link
G FFAR3 free fatty acid receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,305,112...32,307,223 JBrowse link
G FOXO1 forkhead box O1 involved_in ISO (MGI:2388494|PMID:12219087), (MGI:6101624|PMID:27457971) UniProt PMID:12219087 PMID:27457971 MGI:2388494 MGI:6101624 NCBI chr13:21,763,729...21,874,279 JBrowse link
G GHRL ghrelin and obestatin prepropeptide acts_upstream_of_or_within
involved_in		 ISO
IEA		 PMID:17130496
(PMID:17130496)		 MGI
Ensembl		 PMID:17130496 GO_REF:0000107 RGD:8553721 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GHSR growth hormone secretagogue receptor acts_upstream_of_or_within ISO PMID:17130496 MGI PMID:17130496 RGD:8553721 NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202 		JBrowse link
G GNAO1 G protein subunit alpha o1 involved_in ISO (PMID:20622165) MGI PMID:20622165 NCBI chr16:36,473,852...36,643,789
Ensembl chr16:55,606,920...55,776,619 		JBrowse link
G GNAZ G protein subunit alpha z involved_in IEA Ensembl GO_REF:0000107 Ensembl chr22:21,719,169...21,746,851 JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO RGD PMID:17491019 RGD:2302227 NCBI chr 4:100,495,205...100,540,589
Ensembl chr 4:111,067,336...111,113,868 		JBrowse link
G HDAC1 histone deacetylase 1 ISO RGD PMID:22772764 RGD:9590127 NCBI chr 1:31,578,373...31,619,970
Ensembl chr 1:32,585,791...32,626,410 		JBrowse link
G INHBB inhibin subunit beta B acts_upstream_of_or_within ISO (PMID:18480258) MGI PMID:18480258 NCBI chr2B:7,278,944...7,284,632 JBrowse link
G IRS1 insulin receptor substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:113,973,191...114,041,127
Ensembl chr2B:232,849,239...232,852,967 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:45,636,371...45,821,536
Ensembl chr20:46,776,274...46,885,521 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,440,522...17,444,075
Ensembl chr11:17,127,557...17,128,729 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO RGD PMID:16133261 RGD:1581603 NCBI chr11:2,469,750...2,874,467 JBrowse link
G LOC100984543 bone morphogenetic protein 8A involved_in ISO (PMID:22579288) UniProt PMID:22579288 NCBI chr 1:38,776,557...38,815,210 JBrowse link
G MIDN midnolin acts_upstream_of_or_within ISO PMID:24187134 MGI PMID:24187134 RGD:8655525
G MTNR1A melatonin receptor 1A ISO RGD PMID:22288848 RGD:9686057 NCBI chr 4:178,693,869...178,720,351
Ensembl chr 4:190,897,192...190,921,677 		JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:18363673 RGD:9588673 NCBI chr11:87,996,805...88,009,865
Ensembl chr11:91,491,822...91,504,652 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:17130471 RGD:1642149 NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005 		JBrowse link
G NPFF neuropeptide FF-amide peptide precursor ISO RGD PMID:1704109 RGD:2316580 NCBI chr12:35,245,172...35,246,710
Ensembl chr12:36,030,805...36,031,591 		JBrowse link
G PDE8B phosphodiesterase 8B ISO RGD PMID:17991719 RGD:2312519 NCBI chr 5:37,874,089...38,121,322
Ensembl chr 5:38,402,790...38,617,743 		JBrowse link
G PFKL phosphofructokinase, liver type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9287040) Ensembl
MGI		 PMID:9287040 GO_REF:0000107 NCBI chr21:30,557,576...30,584,231
Ensembl chr21:43,857,052...43,878,380 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha involved_in ISO PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24187134) MGI
Ensembl		 PMID:24187134 GO_REF:0000107 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 involved_in ISO PMID:16099819 BHF-UCL PMID:16099819 RGD:8554418 NCBI chr12:119,490,380...119,519,318
Ensembl chr12:122,859,940...122,887,703 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10531320 RGD:10043332 NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 acts_upstream_of_or_within ISO (PMID:15520383) MGI PMID:15520383 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762 		JBrowse link
G REST RE1 silencing transcription factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 involved_in ISO (MGI:5619445|PMID:23092880) CACAO PMID:23092880 MGI:5619445 NCBI chr17:74,973,420...75,389,339
Ensembl chr17:80,705,544...81,118,708 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in ISO (PMID:17994217) UniProt PMID:17994217 NCBI chr 8:40,507,027...40,555,053 JBrowse link
G SIRT4 sirtuin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16959573) Ensembl
MGI		 PMID:16959573 GO_REF:0000107 NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16890542) Ensembl
MGI		 PMID:16890542 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G STXBP5L syntaxin binding protein 5L involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21998599) Ensembl
MGI		 PMID:21998599 GO_REF:0000107 NCBI chr 3:118,022,061...118,529,311
Ensembl chr 3:124,932,110...125,434,515 		JBrowse link
G SYTL4 synaptotagmin like 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16890542) Ensembl
MGI		 PMID:16890542 GO_REF:0000107 NCBI chr  X:89,885,478...89,941,381
Ensembl chr  X:100,024,434...100,051,663 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:17931748 RGD:2306798 NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688 		JBrowse link
G VSNL1 visinin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16731532) Ensembl
MGI		 PMID:16731532 GO_REF:0000107 NCBI chr2A:17,525,561...17,641,277
Ensembl chr2A:17,703,086...17,767,274 		JBrowse link
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:19965390) BHF-UCL PMID:19965390 RGD:2316628 NCBI chr10:107,669,860...107,673,685 JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17360501 RGD:2306172 NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220 		JBrowse link
G ENY2 ENY2 transcription and export complex 2 subunit ISO RGD PMID:22649445 RGD:9590329 NCBI chr 8:105,985,043...105,996,686
Ensembl chr 8:108,129,883...108,141,478 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19805579) Ensembl
MGI		 PMID:19805579 GO_REF:0000107 NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20610886 RGD:5508687 NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785 		JBrowse link
G JAGN1 jagunal homolog 1 ISO RGD PMID:26882284 RGD:11520872 NCBI chr 3:9,835,123...9,838,398
Ensembl chr 3:10,183,760...10,187,064 		JBrowse link
G KLF7 KLF transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:94,307,334...94,399,553
Ensembl chr2B:212,448,337...212,525,403 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 ISO RGD PMID:19690174 RGD:7495848 Ensembl chr2A:102,750,221...102,945,263 JBrowse link
G NDUFAF2 NADH:ubiquinone oxidoreductase complex assembly factor 2 acts_upstream_of_or_within ISO (PMID:22587331) MGI PMID:22587331 NCBI chr 5:52,843,931...53,053,671 JBrowse link
G PDE1C phosphodiesterase 1C ISO RGD PMID:18706893 RGD:2302857 NCBI chr 7:32,225,293...33,037,627
Ensembl chr 7:32,343,701...33,029,405 		JBrowse link
G PDE3B phosphodiesterase 3B ISO RGD PMID:18706893 RGD:2302857 NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616 		JBrowse link
G PDE4C phosphodiesterase 4C ISO RGD PMID:18706893 RGD:2302857 NCBI chr19:17,683,455...17,709,936
Ensembl chr19:18,663,378...18,686,194 		JBrowse link
G PDE8B phosphodiesterase 8B ISO RGD PMID:18706893 RGD:2302857 NCBI chr 5:37,874,089...38,121,322
Ensembl chr 5:38,402,790...38,617,743 		JBrowse link
G PIM3 Pim-3 proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:30,186,716...30,190,270 JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 ISO RGD PMID:20167843 RGD:12904047 NCBI chr11:47,515,304...47,521,529
Ensembl chr11:48,064,931...48,073,474 		JBrowse link
G TBC1D1 TBC1 domain family member 1 ISO RGD PMID:28177704 RGD:150521607 NCBI chr 4:32,217,463...32,466,020
Ensembl chr 4:38,084,075...38,319,842 		JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:21172424 RGD:7204422 NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185 		JBrowse link
positive regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:17724028 GO_REF:0000118 RGD:2301019 NCBI chr12:122,660,621...122,737,421
Ensembl chr12:126,942,340...127,019,372 		JBrowse link
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:20695849 RGD:9588550 NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 involved_in ISO PMID:23766516 UniProt PMID:23766516 RGD:14695075 NCBI chr  X:98,731,109...98,841,067
Ensembl chr  X:109,206,964...109,310,914 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073 		JBrowse link
G ANXA7 annexin A7 acts_upstream_of_or_within_positive_effect ISO (PMID:10570150) MGI PMID:10570150 NCBI chr10:69,923,353...69,962,980
Ensembl chr10:72,381,447...72,420,749 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:7,637,680...7,708,914 JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:18562674 RGD:152177517 NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826 		JBrowse link
G CAPN10 calpain 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:127,838,477...127,851,334
Ensembl chr2B:246,645,630...246,679,169 		JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO RGD PMID:24140090 RGD:11576293 NCBI chr  X:33,967,329...34,374,385
Ensembl chr  X:41,659,295...42,066,570 		JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:22566534 RGD:7205453 NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268 		JBrowse link
G CD38 CD38 molecule ISO RGD PMID:9664081 RGD:2307276 NCBI chr 4:10,228,803...10,295,129
Ensembl chr 4:15,525,835...15,587,677 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in ISO (PMID:20440069)
(PMID:16753580)		 MGI PMID:16753580 PMID:20440069 NCBI chr 1:214,931,514...215,452,739 JBrowse link
G DOC2B double C2 domain beta involved_in ISO (MGI:4457249|PMID:17548353) UniProt PMID:17548353 MGI:4457249 NCBI chr17:19,854...58,336 JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157 		JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:38,680,372...38,688,509
Ensembl chr 5:39,297,424...39,305,370 		JBrowse link
G FFAR1 free fatty acid receptor 1 involved_in ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:16081037 GO_REF:0000107 GO_REF:0000118 RGD:2315053 NCBI chr19:32,298,259...32,300,601
Ensembl chr19:41,034,905...41,035,807 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:32,394,401...32,398,730
Ensembl chr19:41,132,599...41,133,591 		JBrowse link
G GCK glucokinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 in response to glucose stimulation
(PMID:7556622)		 RGD
MGI
Ensembl		 PMID:7556622 PMID:17028192 PMID:17360975 GO_REF:0000107 RGD:1581879 RGD:2301916 NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in IEA UniProt GO_REF:0000104 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GIP gastric inhibitory polypeptide involved_in ISO (PMID:33196462)
(PMID:20138041), (PMID:9075801)		 RGD
MGI		 PMID:8958204 PMID:9075801 PMID:20138041 PMID:33196462 RGD:2312537 NCBI chr17:8,573,104...8,580,424 JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in ISO
IEA		 RGD
Ensembl		 PMID:11014226 GO_REF:0000107 RGD:2312607 NCBI chr19:42,673,553...42,688,059
Ensembl chr19:51,213,090...51,225,293 		JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:24301293 RGD:8662441 NCBI chr 6:119,213,513...119,227,617 JBrowse link
G GLP1R glucagon like peptide 1 receptor ISO RGD PMID:12093887 RGD:625448 NCBI chr 6:38,637,838...38,680,423
Ensembl chr 6:39,823,373...39,855,784 		JBrowse link
G GLRX glutaredoxin ISO RGD PMID:19299446 RGD:9686053 NCBI chr 5:19,526,210...19,535,237
Ensembl chr 5:19,671,965...19,680,685 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:11502802)
(PMID:16959573)		 BHF-UCL
MGI		 PMID:11502802 PMID:16959573 NCBI chr10:83,498,338...83,540,730 JBrowse link
G GLUL glutamate-ammonia ligase ISO ornithine alpha-ketoglutarate-induced secretion RGD PMID:12575909 RGD:2301557 NCBI chr 1:157,882,258...157,891,562
Ensembl chr 1:161,534,106...161,543,411 		JBrowse link
G GNA11 G protein subunit alpha 11 involved_in ISO (PMID:26075576)
(PMID:20440069)		 MGI PMID:20440069 PMID:26075576 NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124 		JBrowse link
G GNAS GNAS complex locus involved_in ISO (PMID:17971513)
(PMID:33196462)
(PMID:34091063)		 MGI PMID:17971513 PMID:33196462 PMID:34091063 NCBI chr20:55,190,607...55,262,245 JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in ISO (MGI:5141337|PMID:21673097) UniProt PMID:21673097 MGI:5141337 NCBI chr 7:1,331,586...1,338,194 JBrowse link
G GPR68 G protein-coupled receptor 68 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22733973) Ensembl
MGI		 PMID:22733973 GO_REF:0000107 NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:10944108 RGD:150540301 NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911 		JBrowse link
G IRS2 insulin receptor substrate 2 involved_in ISO (MGI:4456946|PMID:15572028) BHF-UCL PMID:15572028 MGI:4456946 NCBI chr13:90,886,095...90,917,724 JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA
ISO		 Ensembl
RGD		 PMID:11978636 PMID:29678908 GO_REF:0000107 RGD:243065231 RGD:729103 NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811 		JBrowse link
G JAK2 Janus kinase 2 ISO in response to human growth hormone RGD PMID:16597920 RGD:1641815 NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626 		JBrowse link
G LOC100978090 protein ALEX involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:55,204,188...55,206,608
Ensembl chr20:56,474,459...56,621,747 		JBrowse link
G LOC100986730 guanine nucleotide-binding protein G(q) subunit alpha involved_in ISO (PMID:26075576)
(PMID:20440069)		 MGI PMID:20440069 PMID:26075576 NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849 		JBrowse link
G LOC100987781 calcium release-activated calcium channel protein 1 involved_in ISO (PMID:31664108) MGI PMID:31664108 NCBI chr12:119,229,069...119,243,435 JBrowse link
G LOC103782656 G-protein coupled receptor 39 acts_upstream_of_or_within ISO (PMID:19213841) MGI PMID:19213841 NCBI chr2B:27,429,851...27,431,292 JBrowse link
G LRRC8A leucine rich repeat containing 8 VRAC subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:100,003,969...100,039,859
Ensembl chr 9:128,670,292...128,705,466 		JBrowse link
G MCU mitochondrial calcium uniporter involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:69,243,282...69,435,193
Ensembl chr10:71,845,335...71,898,545 		JBrowse link
G MYRIP myosin VIIA and Rab interacting protein involved_in ISO PMID:17827149 UniProt PMID:17827149 RGD:8554303 NCBI chr 3:39,715,890...40,163,826
Ensembl chr 3:40,079,777...40,433,613 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:15883383 RGD:2306242 NCBI chr 4:39,683,420...39,689,651 JBrowse link
G NLGN2 neuroligin 2 involved_in ISO (PMID:22528485) RGD
CACAO		 PMID:18755801 PMID:22528485 RGD:2314456 RGD:9743981 NCBI chr17:7,438,853...7,454,014 JBrowse link
G NNAT neuronatin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15793245) TreeGrafter
MGI		 PMID:15793245 GO_REF:0000118 NCBI chr20:33,842,071...33,845,575
Ensembl chr20:34,955,234...34,959,493 		JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO RGD PMID:17259388 RGD:2311606 NCBI chr 1:26,174,055...26,176,689
Ensembl chr 1:27,230,362...27,232,942 		JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:17095531 RGD:2305956 NCBI chr10:98,387,144...98,421,105
Ensembl chr10:101,858,879...101,892,479 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO RGD PMID:19635791 RGD:7242950 NCBI chr14:4,872,276...4,882,118
Ensembl chr14:22,996,813...23,006,775 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in ISO
ISS		 RGD
UniProt		 PMID:18439098 GO_REF:0000024 RGD:2306975 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chr 1:182,655,487...182,683,881
Ensembl chr 1:186,934,446...186,961,995 		JBrowse link
G PFKM phosphofructokinase, muscle involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17595219) Ensembl
MGI		 PMID:17595219 GO_REF:0000107 NCBI chr12:40,584,321...40,625,245
Ensembl chr12:41,459,346...41,499,476 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12837755) Ensembl
MGI		 PMID:12837755 GO_REF:0000107 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313 		JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 involved_in ISO PMID:10567574 BHF-UCL PMID:10567574 RGD:633869 NCBI chr12:119,490,380...119,519,318
Ensembl chr12:122,859,940...122,887,703 		JBrowse link
G PTBP1 polypyrimidine tract binding protein 1 ISO RGD PMID:15039777 RGD:10045958 NCBI chr19:319,953...334,945 JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644 		JBrowse link
G RBP4 retinol binding protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887 		JBrowse link
G RPH3AL rabphilin 3A like (without C2 domains) involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:90,816...293,651
Ensembl chr17:146,155...283,278 		JBrowse link
G SERP1 stress associated endoplasmic reticulum protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415102) Ensembl
MGI		 PMID:16415102 GO_REF:0000107 NCBI chr 3:147,559,607...147,564,668
Ensembl chr 3:155,133,115...155,137,241 		JBrowse link
G SIRT3 sirtuin 3 ISO RGD PMID:23397292 RGD:9586042 NCBI chr11:210,052...233,969
Ensembl chr11:255,191...278,732 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:6101624|PMID:27457971) UniProt PMID:27457971 MGI:6101624 NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126 		JBrowse link
G SLC30A8 solute carrier family 30 member 8 involved_in ISO PMID:19479076 BHF-UCL PMID:19479076 RGD:2315022 NCBI chr 8:113,624,785...113,851,633
Ensembl chr 8:116,223,595...116,394,095 		JBrowse link
G SNAP25 synaptosome associated protein 25 ISO RGD PMID:15042624 RGD:1581081 NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in ISO (MGI:3819280|PMID:18477811) UniProt PMID:18477811 MGI:3819280 NCBI chr 6:21,422,846...21,427,779 JBrowse link
G STIM1 stromal interaction molecule 1 involved_in ISO (PMID:30131394), (PMID:31664108)
(PMID:31664108)
(PMID:18452988)		 MGI PMID:18452988 PMID:30131394 PMID:31664108 NCBI chr11:3,726,501...3,954,951
Ensembl chr11:3,840,513...4,065,224 		JBrowse link
G TARDBP TAR DNA binding protein ISO RGD PMID:21127054 RGD:7243008 NCBI chr 1:9,775,084...9,786,710
Ensembl chr 1:10,996,006...11,008,732 		JBrowse link
G TCF7L2 transcription factor 7 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281 		JBrowse link
G TM7SF3 transmembrane 7 superfamily member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:59,298,725...59,340,896
Ensembl chr12:61,913,370...61,955,540 		JBrowse link
G TRH thyrotropin releasing hormone involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:16118471 GO_REF:0000118 RGD:1600419 NCBI chr 3:127,037,069...127,041,299
Ensembl chr 3:134,383,016...134,387,736 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO RGD PMID:16601673 RGD:9999436 NCBI chr21:30,606,825...30,737,313
Ensembl chr21:43,903,811...44,035,298 		JBrowse link
G UCN3 urocortin 3 ISO RGD PMID:17360501 RGD:2306172 NCBI chr10:5,410,501...5,419,650
Ensembl chr10:5,405,683...5,406,168 		JBrowse link
positive regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 ISO RGD PMID:29540530 RGD:41404656 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073 		JBrowse link
G ANO1 anoctamin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:65,064,415...65,287,160
Ensembl chr11:68,473,555...68,576,451 		JBrowse link
G ARRB1 arrestin beta 1 involved_in ISO (MGI:4453294|PMID:19915011) UniProt PMID:19915011 MGI:4453294 NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:24105478) MGI PMID:24105478 NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257 		JBrowse link
G BAIAP3 BAI1 associated protein 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:1,390,160...1,403,978 JBrowse link
G C1QTNF12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22275362) Ensembl
MGI		 PMID:22275362 GO_REF:0000107 Ensembl chr 1:1,200,756...1,205,301 JBrowse link
G C2CD2L C2CD2 like involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24012759) Ensembl
MGI
TreeGrafter		 PMID:24012759 GO_REF:0000107 GO_REF:0000118 NCBI chr11:113,944,939...113,955,296
Ensembl chr11:117,875,077...117,883,581 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:23229155 RGD:13506727 NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:31327268 RGD:18899561 NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864 		JBrowse link
G CRH corticotropin releasing hormone ISO RGD PMID:20080775 RGD:5508172 NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009 		JBrowse link
G DYNLL1 dynein light chain LC8-type 1 ISO RGD PMID:17130471 RGD:1642149 NCBI chr12:118,078,401...118,080,822
Ensembl chr12:121,452,118...121,454,550 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO RGD PMID:29890211 RGD:329951007 NCBI chr16:33,939,300...34,343,419
Ensembl chr16:53,023,425...53,490,231 		JBrowse link
G GCG glucagon involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr2B:49,436,379...49,446,559
Ensembl chr2B:166,806,016...166,811,155 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:16647196 RGD:12905046 NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (MGI:5448527|PMID:20153004) UniProt PMID:20153004 MGI:5448527 NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229 		JBrowse link
G GPR27 G protein-coupled receptor 27 acts_upstream_of_or_within ISO (PMID:22253604) MGI PMID:22253604 NCBI chr 3:71,693,611...71,696,247 JBrowse link
G GPR68 G protein-coupled receptor 68 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22733973) Ensembl
MGI		 PMID:22733973 GO_REF:0000107 NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806 		JBrowse link
G HCFC1 host cell factor C1 involved_in ISO PMID:24250814 UniProt PMID:24250814 RGD:151356618 NCBI chr  X:143,502,159...143,526,418
Ensembl chr  X:153,389,859...153,412,999 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20440072) Ensembl
MGI		 PMID:20440072 GO_REF:0000107 NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885 		JBrowse link
G KIF5B kinesin family member 5B ISO RGD PMID:25462067 RGD:11059539 NCBI chr10:32,138,964...32,186,448
Ensembl chr10:32,731,150...32,778,242 		JBrowse link
G LEPR leptin receptor ISO RGD PMID:9751766 RGD:10412039 NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768 		JBrowse link
G LOC103782656 G-protein coupled receptor 39 acts_upstream_of_or_within ISO (PMID:19213833) MGI PMID:19213833 NCBI chr2B:27,429,851...27,431,292 JBrowse link
G LRP1 LDL receptor related protein 1 ISO RGD PMID:24865476 RGD:13800516 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979 		JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910426) Ensembl
MGI		 PMID:24910426 GO_REF:0000107 NCBI chr 1:143,406,611...143,424,508
Ensembl chr 1:147,132,213...147,151,648 		JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:23354122 RGD:12798521 NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618 		JBrowse link
G NADK NAD kinase ISO RGD PMID:22550069 RGD:13703105 NCBI chr 1:462,860...485,203
Ensembl chr 1:1,619,270...1,642,269 		JBrowse link
G NCOA6 nuclear receptor coactivator 6 ISO RGD PMID:16738321 RGD:9590126 NCBI chr20:31,044,339...31,154,798
Ensembl chr20:32,170,583...32,247,167 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
G OSBP oxysterol binding protein ISO RGD PMID:29540530 RGD:41404656 NCBI chr11:54,800,756...54,841,191
Ensembl chr11:58,252,925...58,291,154 		JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO RGD PMID:20460097 RGD:2326185 NCBI chr 5:68,528,765...68,668,305
Ensembl chr 5:73,563,758...73,710,316 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 acts_upstream_of_or_within ISO (PMID:22253604) MGI PMID:22253604 NCBI chr13:9,199,572...9,206,202 JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISO
IEA		 RGD
Ensembl		 PMID:11278673 GO_REF:0000107 RGD:6482760 NCBI chr22:18,998,060...19,094,507
Ensembl chr22:36,849,794...36,919,509
Ensembl chr22:36,849,794...36,919,509 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta ISO RGD PMID:19965574 RGD:2324877 NCBI chr 6:34,903,798...34,987,208
Ensembl chr 6:36,003,988...36,081,132 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO (MGI:5489045|PMID:23412604) RGD
CACAO		 PMID:23412604 MGI:5489045 RGD:14392803 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:16366736 RGD:9585658 NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:168,002,609...168,033,237
Ensembl chr 3:176,188,184...176,218,722 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029 		JBrowse link
G STX4 syntaxin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:23,917,576...23,933,884
Ensembl chr16:31,400,915...31,411,364 		JBrowse link
G SYBU syntabulin ISO RGD PMID:22975310 RGD:8554225 NCBI chr 8:106,223,046...106,340,418
Ensembl chr 8:108,368,117...108,483,927 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:22701540 RGD:10043784 NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:16806463 RGD:10003029 NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464 		JBrowse link
G TUNAR TCL1 upstream neural differentiation-associated RNA involved_in ISO (PMID:34513312) UniProt PMID:34513312
G VSNL1 visinin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16731532) Ensembl
MGI		 PMID:16731532 GO_REF:0000107 NCBI chr2A:17,525,561...17,641,277
Ensembl chr2A:17,703,086...17,767,274 		JBrowse link
regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:42,461,398...42,531,576
Ensembl chr10:45,639,946...45,710,016 		JBrowse link
G BMAL1 basic helix-loop-helix ARNT like 1 involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr11:13,436,580...13,547,135
Ensembl chr11:13,163,028...13,240,376 		JBrowse link
G CARTPT CART prepropeptide ISO RGD PMID:16443761 RGD:2313632 NCBI chr 5:43,591,683...43,593,586
Ensembl chr 5:44,236,114...44,238,229 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:20,915,198...20,923,530
Ensembl chr17:21,210,798...21,219,172 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:68,391,310...68,509,813
Ensembl chr 4:75,018,898...75,066,726 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19644453 RGD:2314628 NCBI chr 6:86,017,141...86,044,889 JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO RGD PMID:11988095 RGD:1298597 NCBI chr11:63,841,028...63,928,242
Ensembl chr11:67,144,736...67,205,481 		JBrowse link
G EIPR1 EARP complex and GARP complex interacting protein 1 involved_in ISO PMID:3172165 UniProt PMID:3172165 RGD:25671404 NCBI chr2A:3,210,030...3,386,505
Ensembl chr2A:3,137,864...3,310,042 		JBrowse link
G ENSA endosulfine alpha acts_upstream_of_or_within ISO (PMID:9653196) MGI PMID:9653196 NCBI chr 1:125,973,344...125,980,839
Ensembl chr 1:129,599,495...129,629,779 		JBrowse link
G G6PC2 glucose-6-phosphatase catalytic subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:56,178,623...56,187,394
Ensembl chr2B:173,643,660...173,652,424 		JBrowse link
G GCG glucagon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14736883) Ensembl
MGI		 PMID:14736883 GO_REF:0000107 NCBI chr2B:49,436,379...49,446,559
Ensembl chr2B:166,806,016...166,811,155 		JBrowse link
G GCK glucokinase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8530440), (PMID:8954920) Ensembl
MGI
TreeGrafter		 PMID:8530440 PMID:8954920 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751 		JBrowse link
G GIP gastric inhibitory polypeptide involved_in IEA InterPro GO_REF:0000002 NCBI chr17:8,573,104...8,580,424 JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:100,495,205...100,540,589
Ensembl chr 4:111,067,336...111,113,868 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,684,450...40,763,824
Ensembl chr20:41,779,034...41,856,536 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:65,663,764...65,668,732
Ensembl chr12:68,448,861...68,453,829 		JBrowse link
G IL1B interleukin 1 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424 		JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:22037645)
(MGI:5304221|PMID:22037645)		 UniProt PMID:22037645 MGI:5304221 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:17,440,522...17,444,075
Ensembl chr11:17,127,557...17,128,729 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16513828) Ensembl
MGI		 PMID:16513828 GO_REF:0000107 NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519 		JBrowse link
G LOC100982351 ubiquinol-cytochrome c reductase complex assembly factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:33,270,785...33,284,931
Ensembl chr 6:34,379,212...34,393,373 		JBrowse link
G LOC100992916 chymotrypsin-like elastase family member 2A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:14,595,218...14,606,322
Ensembl chr 1:15,589,878...15,604,926 		JBrowse link
G MTNR1B melatonin receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:87,996,805...88,009,865
Ensembl chr11:91,491,822...91,504,652 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:28,984,295...29,021,516
Ensembl chr17:29,471,510...29,617,093 		JBrowse link
G PDE3B phosphodiesterase 3B acts_upstream_of_or_within ISO (PMID:14736883) MGI PMID:14736883 NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616 		JBrowse link
G PER2 period circadian regulator 2 involved_in ISO (MGI:5319572|PMID:22504074) UniProt PMID:22504074 MGI:5319572 NCBI chr2B:125,477,021...125,521,577
Ensembl chr2B:244,328,122...244,371,040 		JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr22:36,796,015...36,814,469 JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in ISO PMID:11978799 UniProt PMID:11978799 RGD:8553382 NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,024,016...3,332,266
Ensembl chr 9:3,223,405...3,398,839 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:115,555,561...115,600,302
Ensembl chr 1:124,755,250...124,800,032 		JBrowse link
G SLC25A22 solute carrier family 25 member 22 involved_in ISO PMID:19584051 UniProt PMID:19584051 RGD:151665733 NCBI chr11:807,886...815,770
Ensembl chr11:851,998...858,121 		JBrowse link
G SLC8B1 solute carrier family 8 member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:110,903,215...110,936,908
Ensembl chr12:114,286,624...114,319,683 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18178930) Ensembl
MGI		 PMID:18178930 GO_REF:0000107 NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045 		JBrowse link
G SSTR5 somatostatin receptor 5 acts_upstream_of_or_within ISO (PMID:15919085) MGI PMID:15919085
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3773625|PMID:18308938) RGD
UniProt		 PMID:17709608 PMID:18308938 MGI:3773625 RGD:2311143 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375 		JBrowse link
G SYT9 synaptotagmin 9 ISO RGD PMID:16165130 RGD:2311147 NCBI chr11:7,350,612...7,565,272
Ensembl chr11:7,032,803...7,247,187 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17046993) Ensembl
MGI		 PMID:17046993 GO_REF:0000107 NCBI chr11:63,120,913...63,132,831
Ensembl chr11:66,429,435...66,441,327 		JBrowse link
G TFAP2B transcription factor AP-2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:50,376,157...50,406,740
Ensembl chr 6:51,635,899...51,664,691 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381 		JBrowse link
regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:102,194,286...102,401,175
Ensembl chr2B:220,668,957...220,873,566 		JBrowse link
G ADCY5 adenylate cyclase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:120,380,094...120,545,725
Ensembl chr 3:127,283,921...127,446,508 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19644667) Ensembl
MGI		 PMID:19644667 GO_REF:0000107 NCBI chr17:72,292,332...72,303,493
Ensembl chr17:77,842,724...77,854,159 		JBrowse link
G BRSK2 BR serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:1,424,873...1,495,630
Ensembl chr11:1,473,129...1,521,339 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E acts_upstream_of_or_within ISO (PMID:11923483), (PMID:15630454) MGI PMID:11923483 PMID:15630454 NCBI chr 1:156,796,855...157,296,987
Ensembl chr 1:160,628,089...160,949,270 		JBrowse link
G CDK16 cyclin dependent kinase 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:39,655,119...39,666,878
Ensembl chr  X:47,512,647...47,524,742 		JBrowse link
G DDRGK1 DDRGK domain containing 1 NOT|involved_in ISO PMID:21494687 ParkinsonsUK-UCL PMID:21494687 RGD:11567254 NCBI chr20:3,276,292...3,290,433
Ensembl chr20:3,038,779...3,052,789 		JBrowse link
G EFNA5 ephrin A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:102,732,268...103,026,746
Ensembl chr 5:108,548,927...108,598,942 		JBrowse link
G EPHA5 EPH receptor A5 involved_in ISO (MGI:5294297|PMID:17448994) UniProt PMID:17448994 MGI:5294297 NCBI chr 4:58,392,771...58,743,604 JBrowse link
G FOXA2 forkhead box A2 involved_in ISO (MGI:5142372|PMID:11875061) BHF-UCL PMID:11875061 MGI:5142372 NCBI chr20:22,519,942...22,524,262 JBrowse link
G HMGN3 high mobility group nucleosomal binding domain 3 acts_upstream_of_or_within ISO (PMID:19651901) MGI PMID:19651901 NCBI chr 6:77,052,498...77,085,956 JBrowse link
G LOC100983183 low-density lipoprotein receptor-related protein 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:6,293,669...6,358,052
Ensembl chr22:23,957,773...23,994,087 		JBrowse link
G LRP5 LDL receptor related protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12509515) TreeGrafter
MGI
Ensembl		 PMID:12509515 GO_REF:0000107 GO_REF:0000118 NCBI chr11:63,396,511...63,534,471
Ensembl chr11:66,735,246...66,839,817 		JBrowse link
G MYT1 myelin transcription factor 1 acts_upstream_of_or_within ISO (PMID:17928203) MGI PMID:17928203 Ensembl chr20:62,108,924...62,151,936 JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,188,390...17,196,315
Ensembl chr17:17,409,669...17,417,600 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 involved_in ISO PMID:28711973 UniProt PMID:28711973 RGD:13800537 NCBI chr11:89,572,252...89,628,251
Ensembl chr11:93,097,709...93,150,981 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19401415) Ensembl
MGI		 PMID:19401415 GO_REF:0000107 NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313 		JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23776622) Ensembl
MGI		 PMID:23776622 GO_REF:0000107 NCBI chr11:112,012,734...112,031,403
Ensembl chr11:115,946,725...115,963,408 		JBrowse link
G SLC9B2 solute carrier family 9 member B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:95,474,854...95,532,311
Ensembl chr 4:106,100,229...106,155,749 		JBrowse link
G STXBP4 syntaxin binding protein 4 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr17:49,058,071...49,253,448
Ensembl chr17:53,923,387...54,118,415 		JBrowse link
G SYBU syntabulin acts_upstream_of_or_within ISO PMID:22975310 MGI PMID:22975310 RGD:8554225 NCBI chr 8:106,223,046...106,340,418
Ensembl chr 8:108,368,117...108,483,927 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19168596) MGI PMID:19168596 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:18930714 RGD:10043296 NCBI chr21:17,483,273...17,925,301
Ensembl chr21:30,868,308...31,016,883 		JBrowse link
G UFM1 ubiquitin fold modifier 1 NOT|involved_in ISO PMID:21494687 ParkinsonsUK-UCL PMID:21494687 RGD:11567254 NCBI chr13:19,571,114...19,584,259
Ensembl chr13:38,162,598...38,175,814 		JBrowse link
G ZBED6 zinc finger BED-type containing 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:179,400,520...179,405,501
Ensembl chr 1:183,691,160...183,694,099 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16440
    cellular process 15499
      export from cell 1022
        secretion by cell 953
          protein secretion 431
            insulin secretion 264
              insulin secretion involved in cellular response to glucose stimulus + 101
              negative regulation of insulin secretion + 60
              positive regulation of insulin secretion + 119
              regulation of insulin secretion + 225
Path 2
Term Annotations click to browse term
  biological_process 16440
    localization 5279
      establishment of localization 4578
        transport 4266
          nitrogen compound transport 1812
            amide transport 402
              peptide transport 344
                peptide secretion 336
                  peptide hormone secretion 328
                    insulin secretion 264
                      insulin secretion involved in cellular response to glucose stimulus + 101
                      negative regulation of insulin secretion + 60
                      positive regulation of insulin secretion + 119
                      regulation of insulin secretion + 225
paths to the root