peptide hormone secretion - Ontology Report

GO_REF:0000107
MGI:1856395 (PMID:16219686)

PMID:16219686

GO_REF:0000107

NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233

Edn1

endothelin 1

involved_in

(PMID:10770212)

PMID:10770212

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

Edn3

endothelin 3

involved_in

(PMID:10770212)

PMID:10770212

NCBI chr 3:163,562,307...163,586,636
Ensembl chr 3:163,562,520...163,585,093

Exoc3l1

exocyst complex component 3-like 1

involved_in

(MGI:3852302|PMID:18480549)

PMID:18480549

MGI:3852302

NCBI chr19:33,166,836...33,174,371
Ensembl chr19:33,166,837...33,172,486

Htt

huntingtin

acts_upstream_of_or_within

MGI:2388032 (PMID:10078572), (PMID:12223581)

PMID:10078572 PMID:12223581

NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070

Ildr1

immunoglobulin-like domain containing receptor 1

acts_upstream_of

(PMID:23863714)

PMID:23863714

NCBI chr11:64,085,774...64,118,760
Ensembl chr11:64,008,566...64,118,760

Smpd3

sphingomyelin phosphodiesterase 3

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3575405 (PMID:15764706)

PMID:15764706

GO_REF:0000107

NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749

corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aqp1

aquaporin 1

acts_upstream_of_or_within

MGI:1857807 (PMID:18511498)

PMID:18511498

NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690

Crhr1

corticotropin releasing hormone receptor 1

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:1267130|PMID:9655498)

PMID:9655498

GO_REF:0000024 GO_REF:0000107 MGI:1267130

NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481

ghrelin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ffar4

free fatty acid receptor 4

involved_in

GO_REF:0000024
(MGI:6383312|PMID:24222669)

PMID:24222669

GO_REF:0000024 MGI:6383312

NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597

growth hormone secretagogue receptor

RGD

PMID:21778696

RGD:12905045

NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865

glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il6

interleukin 6

involved_in

(MGI:3807360|PMID:18719127)

PMID:18719127

MGI:3807360

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cacna1c

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

(PMID:1385406)

PMID:1385406

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

Cdk16

cyclin-dependent kinase 16

involved_in

GO_REF:0000107
(MGI:5447616|PMID:16461345)
GO_REF:0000024

PMID:16461345

GO_REF:0000024 GO_REF:0000107 MGI:5447616

NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148

Ghrh

growth hormone releasing hormone

acts_upstream_of_or_within
involved_in

(PMID:2857452)
MGI:3051561 (PMID:15070777), (PMID:15985453), (PMID:9348175)
GO_REF:0000033

PMID:2857452 PMID:9348175 PMID:15070777 PMID:15985453

GO_REF:0000033

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

Ghrhr

growth hormone releasing hormone receptor

involved_in
acts_upstream_of

GO_REF:0000107
MGI:1856425 (PMID:3008329)

PMID:3008329

GO_REF:0000107

NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776

growth hormone secretagogue receptor

acts_upstream_of_or_within

MGI:1930008 (PMID:15070777)

PMID:15070777

NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865

Rab1a

RAB1A, member RAS oncogene family

involved_in

GO_REF:0000024
(PMID:22939626)

PMID:22939626

GO_REF:0000024

NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248

insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Acvr1c

activin A receptor type 1C

involved_in
acts_upstream_of

GO_REF:0000107
MGI:3512292 (PMID:18480258)

PMID:18480258

GO_REF:0000107

NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327

Acvr2b

activin A receptor type 2B

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:108051 (PMID:17849440)

PMID:17849440

GO_REF:0000107

NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458

Adcyap1

adenylate cyclase activating polypeptide 1

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5525944|PMID:23913443)

PMID:23913443

GO_REF:0000024 GO_REF:0000107 MGI:5525944

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

annexin A1

RGD

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

Anxa7

annexin A7

acts_upstream_of

MGI:95766 (PMID:20440069)

PMID:20440069

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

Cacna1c

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

MGI:2176227|MGI:2674119 (PMID:12881419)

PMID:12881419

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

Cckar

cholecystokinin A receptor

RGD

PMID:9773935

RGD:2313338

NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747

Cplx1

complexin 1

involved_in

(MGI:3688343|PMID:15126625)

PMID:15126625

MGI:3688343

NCBI chr14:1,184,677...1,216,392

Cplx3

complexin 3

involved_in

(MGI:3582382|PMID:15911881)

PMID:15911881

MGI:3582382

NCBI chr 8:58,003,535...58,010,297
Ensembl chr 8:58,003,535...58,010,297

Cyb5r4

cytochrome b5 reductase 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3050973 (PMID:15247412)

PMID:15247412

GO_REF:0000107

NCBI chr 8:87,975,596...88,048,356
Ensembl chr 8:87,981,116...88,045,832

Dgat1

diacylglycerol O-acyltransferase 1

RGD

PMID:12193544

RGD:628375

NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299

Fam3b

FAM3 metabolism regulating signaling molecule B

involved_in

(PMID:12160727)
GO_REF:0000033
(MGI:2384458|PMID:12160727)

PMID:12160727

GO_REF:0000033 MGI:2384458

NCBI chr11:36,831,532...36,863,902
Ensembl chr11:36,831,532...36,869,713

Ffar1

free fatty acid receptor 1

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3713759 (PMID:17395749)

PMID:17395749

GO_REF:0000107

NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272

Fkbp1b

FKBP prolyl isomerase 1B

acts_upstream_of_or_within

MGI:3720261|MGI:3796253 (PMID:18466757)

PMID:18466757

NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653

Glp1r

glucagon-like peptide 1 receptor

involved_in

PMID:10362617

UniProt

PMID:10362617

RGD:8553736

NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241

Gpr119

G protein-coupled receptor 119

acts_upstream_of_or_within

(PMID:15607732)

PMID:15607732

NCBI chr X:127,852,145...127,858,198
Ensembl chr X:127,852,145...127,858,198

G protein-coupled receptor 39

acts_upstream_of

MGI:3723512 (PMID:19213841)

PMID:19213841

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

Gpr68

G protein-coupled receptor 68

acts_upstream_of

MGI:5445001 (PMID:22733973)

PMID:22733973

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

Hmga1

high mobility group AT-hook 1

acts_upstream_of_or_within

MGI:3583805 (PMID:15924147)

PMID:15924147

NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752

Hnf1a

HNF1 homeobox A

involved_in
acts_upstream_of_or_within

(PMID:10333057)
MGI:2154359|MGI:2384429 (PMID:15142986), (PMID:9566924), (PMID:9593777), (PMID:9733737)

PMID:9566924 PMID:9593777 PMID:9733737 PMID:10333057 PMID:15142986

NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104

Hnf1b

HNF1 homeobox B

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2176227|MGI:2670936 (PMID:15142986)

PMID:15142986

GO_REF:0000107

NCBI chr10:68,735,894...68,789,888
Ensembl chr10:68,735,894...68,789,888

Htt

huntingtin

acts_upstream_of_or_within

(PMID:10078572)

PMID:10078572

NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070

Il1rn

interleukin 1 receptor antagonist

acts_upstream_of_or_within

MGI:2157397 (PMID:12975454)

PMID:12975454

NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445

Ildr2

immunoglobulin-like domain containing receptor 2

acts_upstream_of_or_within

MGI:3820395 (PMID:18654634)

PMID:18654634

NCBI chr13:78,518,770...78,580,627
Ensembl chr13:78,518,802...78,576,924

insulin receptor substrate 1

NOT|acts_upstream_of_or_within

MGI:2136643 (PMID:9062343)

PMID:9062343

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

Lep

leptin

acts_upstream_of_or_within

MGI:1343180 (PMID:16141392)

PMID:16141392

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

Mafa

MAF bZIP transcription factor A

involved_in
acts_upstream_of

IBA
ISO

GO_REF:0000033
(PMID:17941991)

PMID:17941991

GO_REF:0000033

NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690

Mc4r

melanocortin 4 receptor

acts_upstream_of_or_within

MGI:1343180 (PMID:16141392)

PMID:16141392

NCBI chr18:60,419,832...60,421,719
Ensembl chr18:60,419,832...60,421,719

Myo5a

myosin VA

acts_upstream_of_or_within

(PMID:15788565)

PMID:15788565

NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918

Neurod1

neuronal differentiation 1

acts_upstream_of

(PMID:17941991)

PMID:17941991

NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649

Nnat

neuronatin

acts_upstream_of

(PMID:15793245)

PMID:15793245

NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834

Park7

Parkinsonism associated deglycase

involved_in

GO_REF:0000024
(MGI:5908331|PMID:22611253)

PMID:22611253

GO_REF:0000024 MGI:5908331

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

Pclo

piccolo (presynaptic cytomatrix protein)

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(PMID:12401793)

PMID:12401793

GO_REF:0000107

NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885

Pdx1

pancreatic and duodenal homeobox 1

acts_upstream_of

(PMID:17941991)

PMID:17941991

NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064

Prkce

protein kinase C, epsilon

involved_in
acts_upstream_of

GO_REF:0000107
(PMID:12837755)

PMID:12837755

GO_REF:0000107

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Ptprn

protein tyrosine phosphatase, receptor type, N

involved_in

UniProtKB:Q6P4T1 (PMID:24843546)
GO_REF:0000107

PMID:24843546

GO_REF:0000107

NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190

Rab3a

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107
PR:Q9EQZ7 (PMID:11056535)

PMID:11056535

GO_REF:0000107

NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336

Rapgef4

Rap guanine nucleotide exchange factor 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(PMID:11598134), (PMID:12401793)

PMID:11598134 PMID:12401793

GO_REF:0000107

NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316

Rims2

regulating synaptic membrane exocytosis 2

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(PMID:11598134)

ParkinsonsUK-UCL
RGD

PMID:11598134

GO_REF:0000024

NCBI chr 7:70,248,104...70,759,134
Ensembl chr 7:70,243,872...70,757,491

Serp1

stress-associated endoplasmic reticulum protein 1

acts_upstream_of

MGI:3652355 (PMID:16415102)

PMID:16415102

NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116

Slc18a2

solute carrier family 18 member A2

RGD

PMID:18577569

RGD:2317338

NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325

Slc30a8

solute carrier family 30 member 8

involved_in

IMP
IBA
ISO

GO_REF:0000033
(MGI:4359332|PMID:19450229)
(PMID:16984975)

PMID:16984975 PMID:19450229 PMID:19479076

GO_REF:0000033 MGI:4359332, RGD:2315022

NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305

Smad2

SMAD family member 2

acts_upstream_of_or_within

MGI:87912 (PMID:17849440)

PMID:17849440

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

Snord33

small nucleolar RNA, C/D box 33

acts_upstream_of_or_within

MGI:1351319|MGI:1351324|MGI:1351325 (PMID:27820699)

PMID:27820699

NCBI chr 1:95,610,699...95,610,783
Ensembl chr 1:95,610,699...95,610,783

Snord34

small nucleolar RNA, C/D box 34

acts_upstream_of_or_within

MGI:1351319|MGI:1351323|MGI:1351324 (PMID:27820699)

PMID:27820699

NCBI chr 8:115,045,817...115,045,883
Ensembl chr 8:115,045,817...115,045,883

Snord35a

small nucleolar RNA, C/D box 35A

acts_upstream_of_or_within

MGI:1351323|MGI:1351324|MGI:1351325 (PMID:27820699)

PMID:27820699

NCBI chr 1:95,610,185...95,610,264
Ensembl chr 1:95,610,185...95,610,264

Snx19

sorting nexin 19

involved_in
acts_upstream_of_or_within

UniProtKB:Q6P4T1 (PMID:24843546)

PMID:24843546

NCBI chr 8:28,829,881...28,867,600
Ensembl chr 8:28,829,886...28,867,061

Srebf1

sterol regulatory element binding transcription factor 1

acts_upstream_of

MGI:2177773 (PMID:16890542)

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

Stx1a

syntaxin 1A

involved_in

(MGI:3789566|PMID:17502420)
GO_REF:0000107

PMID:17502420

GO_REF:0000107 MGI:3789566

NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930

Stxbp3

syntaxin binding protein 3

acts_upstream_of_or_within

MGI:3573931 (PMID:19188424)

PMID:19188424

NCBI chr 2:196,442,738...196,485,733
Ensembl chr 2:196,442,634...196,485,671

Sytl4

synaptotagmin-like 4

involved_in
acts_upstream_of

GO_REF:0000107
(PMID:16890542)

GO_REF:0000107

NCBI chr X:97,135,496...97,185,867
Ensembl chr X:97,135,500...97,185,854

Vgf

VGF nerve growth factor inducible

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:104663 (PMID:16141392)

PMID:16141392

GO_REF:0000107

NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341

insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Atg7

autophagy related 7

acts_upstream_of

MGI:3587769 (PMID:24105478)

PMID:24105478

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

Ccdc186

coiled-coil domain containing 186

acts_upstream_of_or_within

(PMID:27293546)

PMID:27293546

NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935

Cltrn

collectrin, amino acid transport regulator

acts_upstream_of_positive_effect
involved_in

(PMID:16330323)
GO_REF:0000107

PMID:16330323

GO_REF:0000107

NCBI chr X:30,361,967...30,395,264
Ensembl chr X:30,361,967...30,395,349

carboxypeptidase E

RGD

NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233

Fkbp1b

FKBP prolyl isomerase 1B

acts_upstream_of

MGI:2182644 (PMID:19805579)

PMID:19805579

NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653

G protein-coupled receptor 39

acts_upstream_of

MGI:3701833 (PMID:19213833)

PMID:19213833

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

Hif1a

hypoxia inducible factor 1 subunit alpha

involved_in
acts_upstream_of

GO_REF:0000107
MGI:2677892 (PMID:20440072)

PMID:12031972 PMID:21732083

PMID:20440072

GO_REF:0000107

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

Ptprn

protein tyrosine phosphatase, receptor type, N

involved_in

ISS
IBA
ISO

GO_REF:0000024
GO_REF:0000033
(MGI:3624867|PMID:12031972), (MGI:5141326|PMID:21732083)

UniProt
GO_Central
RGD

GO_REF:0000024 GO_REF:0000033 MGI:3624867 MGI:5141326

NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190

Ptprn2

protein tyrosine phosphatase, receptor type N2

involved_in

ISS
IBA
IEA
ISO

GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:5141326|PMID:21732083)

UniProt
GO_Central
Ensembl
RGD

PMID:21732083

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5141326

NCBI chr 6:137,439,572...138,191,575
Ensembl chr 6:137,439,540...138,191,575

Rab11b

RAB11B, member RAS oncogene family

involved_in

GO_REF:0000024
(MGI:4352608|PMID:19335615)

PMID:19335615

GO_REF:0000024 MGI:4352608

NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:14,521,368...14,534,593

Rab11fip2

RAB11 family interacting protein 2

involved_in

(MGI:4352608|PMID:19335615)

PMID:19335615

MGI:4352608

NCBI chr 1:258,950,535...259,094,555
Ensembl chr 1:258,923,873...259,093,752

Rab11fip5

RAB11 family interacting protein 5

involved_in

(MGI:4352608|PMID:19335615)

PMID:19335615

MGI:4352608

NCBI chr 4:117,871,301...117,908,819
Ensembl chr 4:117,871,308...117,908,741

Raf1

Raf-1 proto-oncogene, serine/threonine kinase

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3497907 (PMID:21817126)

PMID:21817126

GO_REF:0000107

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

Rbm4

RNA binding motif protein 4

acts_upstream_of_or_within

MGI:5467987|MGI:5467988 (PMID:23129807)

PMID:23129807

NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380

Selenot

selenoprotein T

involved_in
acts_upstream_of_or_within

GO_REF:0000024
MGI:5544732 (PMID:23913443)
GO_REF:0000107

PMID:1846945 PMID:1846945

PMID:23913443

GO_REF:0000024 GO_REF:0000107

NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427

negative regulation of corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Crhbp

corticotropin releasing hormone binding protein

involved_in

IEA
IBA
IDA
ISO

GO_REF:0000107
GO_REF:0000033
PMID:1846945
(PMID:1846945)

Ensembl
GO_Central
RGD

GO_REF:0000033 GO_REF:0000107, RGD:69816

NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710

negative regulation of glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CART prepropeptide

RGD

NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713

Crh

corticotropin releasing hormone

involved_in

IDA
IBA

GO_REF:0000033

PMID:12606499

GO_REF:0000033, RGD:704397

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

Lep

leptin

involved_in

(MGI:4889014|PMID:21234744)

PMID:21234744

MGI:4889014

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

nucleobindin 2

RGD

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

negative regulation of growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Kalrn

kalirin, RhoGEF kinase

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:5551305 (PMID:23116210)

PMID:23116210

GO_REF:0000107

NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610

Madd

MAP-kinase activating death domain

RGD

PMID:16473592

RGD:9588640

NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701

Ptpn11

protein tyrosine phosphatase, non-receptor type 11

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3522021 (PMID:15520383)

PMID:15520383

GO_REF:0000107

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

sirtuin 1

RGD

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

Sstr1

somatostatin receptor 1

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802

Sstr2

somatostatin receptor 2

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351

Sstr3

somatostatin receptor 3

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769

negative regulation of insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abcc8

ATP binding cassette subfamily C member 8

involved_in

MGI:2388392 (PMID:16924481), (PMID:25771886)

PMID:16924481 PMID:25771886 PMID:15163199

RGD:1598646

NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510

Acvr1c

activin A receptor type 1C

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3512292 (PMID:18480258)

PMID:18480258

GO_REF:0000107

NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327

Adra2a

adrenoceptor alpha 2A

involved_in

(PMID:10952463)
(PMID:17992256), (PMID:1898674)

PMID:1898674 PMID:10952463 PMID:17992256

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Bmp8a

bone morphogenetic protein 8a

involved_in

(PMID:22579288)

PMID:22579288

NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785

Ccn3

cellular communication network factor 3

involved_in

GO_REF:0000024
(MGI:5517610|PMID:23705021)

PMID:23705021

GO_REF:0000024 MGI:5517610

NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019

Chga

chromogranin A

involved_in

IBA

GO_REF:0000033

GO_Central

GO_REF:0000033

NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398

dopamine receptor D2

RGD

NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875

F2rl1

F2R like trypsin receptor 1

involved_in

MGI:2179844 (PMID:17992256)

PMID:17992256

NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226

Fam3d

FAM3 metabolism regulating signaling molecule D

involved_in

GO_REF:0000024
(PMID:12160727)

PMID:12160727

GO_REF:0000024

NCBI chr15:16,538,881...16,574,468
Ensembl chr15:16,539,489...16,573,034

Fbn1

fibrillin 1

involved_in

(MGI:6442875|PMID:30997682)

PMID:30997682

MGI:6442875

NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889

Ffar2

free fatty acid receptor 2

involved_in

MGI:2685324 (PMID:25581519), (PMID:26075576)

PMID:25581519 PMID:26075576

NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033

Ffar3

free fatty acid receptor 3

involved_in

MGI:2441731|MGI:3829251 (PMID:25581519), (PMID:26091414), (PMID:32073900)

PMID:25581519 PMID:26091414 PMID:32073900

NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849

Foxo1

forkhead box O1

involved_in

GO_REF:0000024
(MGI:2388494|PMID:12219087), (MGI:6101624|PMID:27457971)

PMID:12219087 PMID:27457971

GO_REF:0000024 MGI:2388494 MGI:6101624

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

ghrelin and obestatin prepropeptide

acts_upstream_of_or_within

PMID:17130496
MGI:3709886 (PMID:17130496)

PMID:17130496 PMID:17130496

RGD:8553721

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

growth hormone secretagogue receptor

acts_upstream_of_or_within

PMID:17130496

MGI

PMID:17130496

RGD:8553721

NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865

Gnao1

G protein subunit alpha o1

involved_in

GO_REF:0000107
MGI:4941848 (PMID:20622165)

PMID:20622165

GO_REF:0000107

NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493

Gnaz

G protein subunit alpha z

involved_in

MGI:3575007 (PMID:18096703)

PMID:18096703

NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907

Hadh

hydroxyacyl-CoA dehydrogenase

RGD

PMID:17491019

RGD:2302227

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

Hdac1

histone deacetylase 1

RGD

PMID:22772764

RGD:9590127

NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111

Inhbb

inhibin subunit beta B

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:1857203 (PMID:18480258)
GO_REF:0000024

PMID:18480258

GO_REF:0000024 GO_REF:0000107

NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832

insulin receptor substrate 1

involved_in

IMP
IEA
ISO

PMID:12435589
GO_REF:0000107
(PMID:15572028)

PMID:15572028 PMID:12435589

GO_REF:0000107, RGD:729325

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

Kcnb1

potassium voltage-gated channel subfamily B member 1

involved_in

GO_REF:0000107
(MGI:3770494|PMID:17767909)
GO_REF:0000024

PMID:17767909

GO_REF:0000024 GO_REF:0000107 MGI:3770494

NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194

Kcnj11

potassium inwardly-rectifying channel, subfamily J, member 11

involved_in

(PMID:8923010)
MGI:2178821 (PMID:16924481), (PMID:33196462)

PMID:8923010 PMID:16924481 PMID:33196462

NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082

Kcnq1

potassium voltage-gated channel subfamily Q member 1

RGD

PMID:16133261

RGD:1581603

NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669

Midn

midnolin

acts_upstream_of_or_within

PMID:24187134

MGI

PMID:24187134

RGD:8655525

NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752

Mtnr1a

melatonin receptor 1A

RGD

PMID:22288848

RGD:9686057

NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919

Mtnr1b

melatonin receptor 1B

RGD

PMID:18363673

RGD:9588673

NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737

Nos1

nitric oxide synthase 1

RGD

PMID:17130471

RGD:1642149

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

Npff

neuropeptide FF-amide peptide precursor

RGD

PMID:1704109

RGD:2316580

NCBI chr 7:133,654,530...133,655,319

phosphodiesterase 8B

RGD

NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209

Pfkl

phosphofructokinase, liver type

acts_upstream_of_or_within

(PMID:9287040)

PMID:9287040

NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315

Ppp3ca

protein phosphatase 3 catalytic subunit alpha

involved_in

PMID:19965390

BHF-UCL

PMID:19965390

RGD:2316628

NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974

Prkn

parkin RBR E3 ubiquitin protein ligase

involved_in
acts_upstream_of_or_within

ParkinsonsUK-UCL
Ensembl
RGD

GO_REF:0000024
GO_REF:0000107
(PMID:24187134)

PMID:24187134

GO_REF:0000024 GO_REF:0000107

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

Psmd9

proteasome 26S subunit, non-ATPase 9

involved_in

PMID:16099819

BHF-UCL

PMID:16099819

RGD:8554418

NCBI chr12:33,337,182...33,357,468

Ptger3

prostaglandin E receptor 3

RGD

PMID:10531320

RGD:10043332

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

Ptpn11

protein tyrosine phosphatase, non-receptor type 11

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3522021 (PMID:15520383)

PMID:15520383

GO_REF:0000107

NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925

Rest

RE1-silencing transcription factor

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:20942606)

PMID:20942606

GO_REF:0000024 GO_REF:0000107

NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354

Rptor

regulatory associated protein of MTOR, complex 1

involved_in

(MGI:5619445|PMID:23092880)

PMID:23092880

MGI:5619445

NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983

Sfrp1

secreted frizzled-related protein 1

involved_in

GO_REF:0000107
(PMID:17994217)

PMID:17994217

GO_REF:0000107

NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286

Sirt4

sirtuin 4

involved_in
acts_upstream_of_or_within

(PMID:17715127)
MGI:3769237|MGI:95753 (PMID:16959573)

PMID:16959573 PMID:17715127

NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439

Srebf1

sterol regulatory element binding transcription factor 1

acts_upstream_of_or_within

MGI:2177773 (PMID:16890542)

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

Stxbp5l

syntaxin binding protein 5L

acts_upstream_of_or_within

(PMID:21998599)

PMID:21998599

NCBI chr11:63,334,667...63,654,270
Ensembl chr11:63,334,667...63,657,014

Sytl4

synaptotagmin-like 4

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(PMID:16890542)

GO_REF:0000107

NCBI chr X:97,135,496...97,185,867
Ensembl chr X:97,135,500...97,185,854

urotensin 2

RGD

NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237

Vsnl1

visinin-like 1

acts_upstream_of_or_within

(PMID:16731532)

PMID:16731532

NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479

negative regulation of insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adra2a

adrenoceptor alpha 2A

involved_in

ISO
IMP

(PMID:19965390)

PMID:19965390 PMID:19965390

RGD:2316628

NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365

Crhr2

corticotropin releasing hormone receptor 2

RGD

PMID:17360501

RGD:2306172

NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904

Eny2

ENY2, transcription and export complex 2 subunit

RGD

PMID:22649445

RGD:9590329

NCBI chr 7:75,581,215...75,605,903
Ensembl chr 7:75,581,240...75,605,897

Fkbp1b

FKBP prolyl isomerase 1B

acts_upstream_of_or_within

MGI:2182644 (PMID:19805579)

PMID:19805579

NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653

Hmgcr

3-hydroxy-3-methylglutaryl-CoA reductase

RGD

PMID:20610886

RGD:5508687

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

jagunal homolog 1

RGD

NCBI chr 4:146,591,577...146,596,287
Ensembl chr 4:146,591,510...146,596,288

Klf7

KLF transcription factor 7

involved_in

(PMID:16339272)

PMID:16339272

NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261

Map4k4

mitogen-activated protein kinase kinase kinase kinase 4

RGD

PMID:19690174

RGD:7495848

NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698

Mup4l1

major urinary protein 4 like 1

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr 5:75,221,340...75,224,797
Ensembl chr 5:75,142,157...75,564,845

Ndufaf2

NADH:ubiquinone oxidoreductase complex assembly factor 2

acts_upstream_of_or_within

(PMID:22587331)

PMID:22587331

NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316

phosphodiesterase 1C

RGD

NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219

phosphodiesterase 3B

RGD

NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334

phosphodiesterase 4C

RGD

NCBI chr16:18,690,727...18,711,555
Ensembl chr16:18,691,700...18,710,640

phosphodiesterase 8B

RGD

NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209

Pim3

Pim-3 proto-oncogene, serine/threonine kinase

involved_in

GO_REF:0000024
GO_REF:0000107
(MGI:5294526|PMID:21099329)

PMID:21099329

GO_REF:0000024 GO_REF:0000107 MGI:5294526

NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587

Ptpmt1

protein tyrosine phosphatase, mitochondrial 1

RGD

PMID:20167843

RGD:12904047

NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427

Tbc1d1

TBC1 domain family member 1

RGD

PMID:28177704

RGD:150521607

NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499

uncoupling protein 2

RGD

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

negative regulation of peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pparg

peroxisome proliferator-activated receptor gamma

involved_in

(MGI:5486574|PMID:11387233)

PMID:11387233

MGI:5486574

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

negative regulation of prolactin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A5

RGD

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

negative regulation of somatostatin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ffar4

free fatty acid receptor 4

involved_in

GO_REF:0000024
(MGI:5575837|PMID:24663807)

PMID:24663807

GO_REF:0000024 MGI:5575837

NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597

Gal

galanin and GMAP prepropeptide

involved_in

(PMID:8837218)

NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959

insulin receptor substrate 1

involved_in

PMID:12435589

BHF-UCL

PMID:12435589

RGD:729325

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

Npy

neuropeptide Y

involved_in

(PMID:8837218)

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

positive regulation of calcitonin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptger3

prostaglandin E receptor 3

RGD

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

Ptger4

prostaglandin E receptor 4

RGD

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

positive regulation of corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apelin

RGD

NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391

Crh

corticotropin releasing hormone

involved_in

IDA
ISO
IMP

(PMID:11329063)

PMID:11329063 PMID:7477349 PMID:20663987

RGD:70047, RGD:5508201

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

Ecrg4

ECRG4 augurin precursor

involved_in

UniProtKB:D4A540-PRO_0000415564 (PMID:20233222)

PMID:20233222

NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595

ghrelin and obestatin prepropeptide

involved_in

(PMID:12566947)

PMID:12566947

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

Lif

LIF, interleukin 6 family cytokine

RGD

PMID:20160138

RGD:2326054

NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482

Pex5l

peroxisomal biogenesis factor 5-like

RGD

PMID:11278749

RGD:737646

NCBI chr 2:115,694,868...115,908,365
Ensembl chr 2:115,700,972...115,913,628

Rab8b

RAB8B, member RAS oncogene family

RGD

PMID:11278749

RGD:737646

NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384

Ucn

urocortin

involved_in

(PMID:11329063)

PMID:11329063 PMID:7477349

RGD:70047

NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950

positive regulation of corticotropin-releasing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apelin

RGD

NCBI chr X:127,180,801...127,213,567
Ensembl chr X:127,203,823...127,213,391

Ecrg4

ECRG4 augurin precursor

involved_in

UniProtKB:D4A540-PRO_0000415564 (PMID:20233222)

PMID:20233222

NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595

Tnfsf11

TNF superfamily member 11

involved_in

(MGI:4413614|PMID:19940926)
GO_REF:0000107

PMID:19940926

GO_REF:0000107 MGI:4413614

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

positive regulation of glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aimp1

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

involved_in

(MGI:3689764|PMID:17001013)

PMID:17001013

MGI:3689764

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

Ffar4

free fatty acid receptor 4

involved_in

GO_REF:0000024
(MGI:5588067|PMID:24742677)

PMID:24742677

GO_REF:0000024 MGI:5588067

NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597

insulin receptor substrate 1

involved_in

PMID:12435589

BHF-UCL

PMID:12435589

RGD:729325

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

positive regulation of growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcyap1

adenylate cyclase activating polypeptide 1

RGD

PMID:18198219

RGD:2325273

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

Arhgef7

Rho guanine nucleotide exchange factor 7

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(PMID:21828338)

PMID:21828338

GO_REF:0000107

NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697

Drd2

dopamine receptor D2

acts_upstream_of_or_within

MGI:1857875 (PMID:11897683)

PMID:11897683

NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875

Gabbr1

gamma-aminobutyric acid type B receptor subunit 1

RGD

PMID:12218349

RGD:2315498

NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994

Ghrh

growth hormone releasing hormone

acts_upstream_of_or_within
involved_in

(PMID:3008329)
(PMID:15538933), (PMID:18329818), (PMID:8421089)

PMID:3008329 PMID:8421089 PMID:15538933 PMID:18329818 PMID:10579333 More...

RGD:1624957, RGD:5687318

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

Ghrhr

growth hormone releasing hormone receptor

acts_upstream_of_or_within
involved_in

IMP
ISO
IEA

MGI:1856425 (PMID:3008329), (PMID:6303755), (PMID:978118)
GO_REF:0000107

PMID:978118 PMID:3008329 PMID:6303755 PMID:23825127

GO_REF:0000107, RGD:10401239

NCBI chr 4:84,498,159...84,532,851
Ensembl chr 4:84,500,212...84,532,776

ghrelin and obestatin prepropeptide

involved_in

ISO
IBA
IDA

(PMID:12566947), (PMID:18329818)
GO_REF:0000033
PMID:10604470

PMID:12566947 PMID:18329818 PMID:10604470

GO_REF:0000033, RGD:625505

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

intersectin 1

RGD

NCBI chr11:30,978,590...31,160,645
Ensembl chr11:30,978,590...31,160,645

Kiss1

KiSS-1 metastasis-suppressor

RGD

PMID:17532794

RGD:2292159

NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612

O-GlcNAcase

RGD

NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359

Selenot

selenoprotein T

involved_in

PMID:18198219

UniProt

PMID:18198219

RGD:2325273

NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427

Serp1

stress-associated endoplasmic reticulum protein 1

acts_upstream_of_or_within

MGI:3652355 (PMID:16415102)

PMID:16415102

NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116

positive regulation of insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Aacs

acetoacetyl-CoA synthetase

involved_in

IMP
IBA

GO_REF:0000033

PMID:17724028

GO_REF:0000033, RGD:2301019

NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954

Abat

4-aminobutyrate aminotransferase

RGD

PMID:20695849

RGD:9588550

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

Acsl4

acyl-CoA synthetase long-chain family member 4

involved_in

PMID:23766516

UniProt

PMID:23766516

RGD:14695075

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

Adcy8

adenylate cyclase 8

involved_in

MGI:2176596 (PMID:25403481), (PMID:9075801)

PMID:9075801 PMID:25403481

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

Anxa7

annexin A7

acts_upstream_of_or_within_positive_effect

MGI:2159005 (PMID:10570150)

PMID:10570150

NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385

Bad

BCL2-associated agonist of cell death

involved_in

GO_REF:0000024
(MGI:3778846|PMID:18223655)

PMID:18223655

GO_REF:0000024 MGI:3778846

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

Blk

BLK proto-oncogene, Src family tyrosine kinase

involved_in

(PMID:19667185)

PMID:19667185

NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031

Cacna1c

calcium voltage-gated channel subunit alpha1 C

RGD

PMID:18562674

RGD:152177517

NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648

Capn10

calpain 10

involved_in

GO_REF:0000107
(PMID:15471947)

PMID:15471947

GO_REF:0000107

NCBI chr 9:93,498,132...93,510,494
Ensembl chr 9:93,498,478...93,510,494

Cask

calcium/calmodulin dependent serine protein kinase

RGD

PMID:24140090

RGD:11576293

NCBI chr X:8,899,500...9,243,014
Ensembl chr X:8,899,833...9,238,694

Casr

calcium-sensing receptor

RGD

PMID:22566534

RGD:7205453

NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811

CD38 molecule

RGD

NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986

Chrm3

cholinergic receptor, muscarinic 3

involved_in

MGI:3770175 (PMID:16753580), (PMID:20440069)

PMID:16753580 PMID:20440069

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

Doc2b

double C2 domain beta

involved_in

GO_REF:0000024
(MGI:4457249|PMID:17548353)
GO_REF:0000107

PMID:17548353

GO_REF:0000024 GO_REF:0000107 MGI:4457249

NCBI chr10:60,628,029...60,653,267
Ensembl chr10:60,628,029...60,653,267

coagulation factor II, thrombin

involved_in

GO_REF:0000107
(PMID:26742564)

PMID:26742564

GO_REF:0000107

NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486

F2rl2

coagulation factor II (thrombin) receptor-like 2

involved_in

GO_REF:0000107
MGI:88380 (PMID:26742564)

RGD
GO_Central
Ensembl
UniProt

PMID:26742564

GO_REF:0000107

NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098

Ffar1

free fatty acid receptor 1

involved_in

IMP
ISO
IBA
IEA
ISS

(MGI:5607397|PMID:24130766), (PMID:31664108)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024

PMID:24130766 PMID:31664108 PMID:16081037

GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5607397, RGD:2315053

NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272

Ffar2

free fatty acid receptor 2

involved_in

(PMID:26075576)

PMID:26075576

NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033

Gck

glucokinase

acts_upstream_of_or_within
involved_in

IDA
ISO
IEA
ISS

(PMID:7556622)
GO_REF:0000107
(MGI:3819280|PMID:18477811)
(PMID:8132752), (PMID:8878425)
GO_REF:0000024
in response to glucose stimulation

RGD
Ensembl
UniProt

PMID:7556622 PMID:8132752 PMID:8878425 PMID:18477811 PMID:17028192 More...

GO_REF:0000024 GO_REF:0000107 MGI:3819280, RGD:1581879, RGD:2301916

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

ghrelin and obestatin prepropeptide

involved_in

IDA
IEA

PMID:11756331
GO_REF:0000104

UniProt

PMID:11756331

GO_REF:0000104, RGD:8554453

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

Gip

gastric inhibitory polypeptide

involved_in

IMP
ISO

MGI:95674 (PMID:20138041), (PMID:33196462), (PMID:9075801)

PMID:9075801 PMID:20138041 PMID:33196462 PMID:8958204

RGD:2312537

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

Gipr

gastric inhibitory polypeptide receptor

involved_in

IMP
ISO

MGI:2149964|MGI:95674 (PMID:15111503), (PMID:23099862)

PMID:15111503 PMID:23099862 PMID:11014226

RGD:2312607

NCBI chr 1:78,804,287...78,814,462
Ensembl chr 1:78,805,593...78,814,462

Gja1

gap junction protein, alpha 1

RGD

PMID:24301293

RGD:8662441

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

Glp1r

glucagon-like peptide 1 receptor

RGD

PMID:12093887

RGD:625448

NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241

glutaredoxin

RGD

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

Glud1

glutamate dehydrogenase 1

involved_in
acts_upstream_of_or_within

(PMID:11502802)
MGI:1922637 (PMID:16959573)

PMID:11502802 PMID:16959573

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

Glul

glutamate-ammonia ligase

ornithine alpha-ketoglutarate-induced secretion

RGD

PMID:12575909

RGD:2301557

NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108

Gna11

G protein subunit alpha 11

involved_in

GO_REF:0000107
MGI:95766|MGI:95776 (PMID:20440069), (PMID:26075576)

PMID:20440069 PMID:26075576

GO_REF:0000107

NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812

Gnaq

G protein subunit alpha q

involved_in

GO_REF:0000107
MGI:95766|MGI:95776 (PMID:20440069), (PMID:26075576)

PMID:20440069 PMID:26075576

GO_REF:0000107

NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672

Gnas

GNAS complex locus

involved_in

GO_REF:0000107
MGI:3609165|MGI:95674 (PMID:17971513), (PMID:33196462), (PMID:34091063)

PMID:17971513 PMID:33196462 PMID:34091063

GO_REF:0000107

NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262

Gper1

G protein-coupled estrogen receptor 1

involved_in

GO_REF:0000107
(MGI:5141337|PMID:21673097)
GO_REF:0000024

PMID:21673097

GO_REF:0000024 GO_REF:0000107 MGI:5141337

NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889

G protein-coupled receptor 39

acts_upstream_of_or_within

MGI:3723512 (PMID:19213841)

PMID:19213841

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

Gpr68

G protein-coupled receptor 68

acts_upstream_of_or_within

MGI:5445001 (PMID:22733973)

PMID:22733973

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

HNF1 homeobox A

RGD

NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104

Irs2

insulin receptor substrate 2

involved_in

(MGI:4456946|PMID:15572028)

PMID:15572028

MGI:4456946

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

Isl1

ISL LIM homeobox 1

involved_in

IMP
IEA
ISO

GO_REF:0000107
(PMID:19619559)

PMID:19619559 PMID:11978636 PMID:29678908

GO_REF:0000107, RGD:729103, RGD:243065231

NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584

Itpr1

inositol 1,4,5-trisphosphate receptor, type 1

involved_in

GO_REF:0000107
MGI:88031 (PMID:10570150), (PMID:26075576), (PMID:31664108)

PMID:10570150 PMID:26075576 PMID:31664108

GO_REF:0000107

NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491

Jak2

Janus kinase 2

in response to human growth hormone

RGD

PMID:16597920

RGD:1641815

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

Lrrc8a

leucine rich repeat containing 8 VRAC subunit A

involved_in

ISS

GO_REF:0000024

UniProt

GO_REF:0000024

NCBI chr 3:13,509,577...13,537,174
Ensembl chr 3:13,510,513...13,536,202

Mcu

mitochondrial calcium uniporter

involved_in

(PMID:22829870)

PMID:22829870

NCBI chr20:27,417,529...27,580,110
Ensembl chr20:27,417,526...27,580,110

Myrip

myosin VIIA and Rab interacting protein

involved_in

PMID:17827149

UniProt

PMID:17827149

RGD:8554303

NCBI chr 8:120,017,749...120,184,821
Ensembl chr 8:120,017,524...120,183,833

NK6 homeobox 1

RGD

NCBI chr14:7,969,756...7,976,689
Ensembl chr14:7,969,756...7,976,681

Nlgn2

neuroligin 2

involved_in

IDA
ISO
IEA
IMP

(PMID:22528485)
GO_REF:0000107

PMID:22528485 PMID:22528485 PMID:18755801

GO_REF:0000107, RGD:9743981, RGD:2314456

NCBI chr10:54,544,461...54,557,854
Ensembl chr10:54,544,588...54,558,434

Nnat

neuronatin

involved_in
acts_upstream_of_or_within

IBA
ISO

GO_REF:0000033
(PMID:15793245)

PMID:15793245

GO_REF:0000033

NCBI chr 3:146,225,941...146,228,868
Ensembl chr 3:146,226,407...146,228,834

Nr0b2

nuclear receptor subfamily 0, group B, member 2

RGD

PMID:17259388

RGD:2311606

NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609

O-GlcNAcase

RGD

NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359

Orai1

ORAI calcium release-activated calcium modulator 1

involved_in

(PMID:31664108)

PMID:31664108

NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405

Pck2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

RGD

PMID:19635791

RGD:7242950

NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283

Pdx1

pancreatic and duodenal homeobox 1

involved_in

IMP
ISO
ISS

(MGI:2388494|PMID:12219087)
GO_REF:0000024

PMID:12219087 PMID:18439098

GO_REF:0000024 MGI:2388494, RGD:2306975

NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064

Pfkfb2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

RGD

PMID:16980436

RGD:2304071

NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699

Pfkm

phosphofructokinase, muscle

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3759504 (PMID:17595219)

PMID:17595219

GO_REF:0000107

NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192

Plcb1

phospholipase C beta 1

involved_in

GO_REF:0000107
MGI:6460327|MGI:88031 (PMID:10570150), (PMID:26075576), (PMID:31268747)

PMID:10570150 PMID:26075576 PMID:31268747

GO_REF:0000107

NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869

Prkaca

protein kinase cAMP-activated catalytic subunit alpha

involved_in

GO_REF:0000107
(PMID:23349500), (PMID:25475437), (PMID:9075801)

PMID:9075801 PMID:23349500 PMID:25475437

GO_REF:0000107

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

Prkar1a

protein kinase cAMP-dependent type I regulatory subunit alpha

involved_in

(PMID:9075801)

PMID:9075801

NCBI chr10:94,621,042...94,639,534
Ensembl chr10:94,620,039...94,639,041

Prkcb

protein kinase C, beta

involved_in

GO_REF:0000107
(PMID:27226533)

PMID:27226533

GO_REF:0000107

NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536

Prkce

protein kinase C, epsilon

involved_in
acts_upstream_of_or_within

GO_REF:0000107
(PMID:12837755)

PMID:12837755

GO_REF:0000107

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Psmd9

proteasome 26S subunit, non-ATPase 9

involved_in

PMID:10567574

BHF-UCL

PMID:10567574

RGD:633869

NCBI chr12:33,337,182...33,357,468

Ptbp1

polypyrimidine tract binding protein 1

RGD

PMID:15039777

RGD:10045958

NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397

Rapgef4

Rap guanine nucleotide exchange factor 4

involved_in

GO_REF:0000107
(PMID:11598134)

PMID:11598134

GO_REF:0000107

NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316

Rbp4

retinol binding protein 4

involved_in

(PMID:16034410)
GO_REF:0000107

PMID:16034410

GO_REF:0000107

NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399

Rph3al

rabphilin 3A-like (without C2 domains)

involved_in

(MGI:3044444|PMID:15159548)

PMID:15159548

MGI:3044444

NCBI chr10:60,689,943...60,833,354
Ensembl chr10:60,690,031...60,801,883

Serp1

stress-associated endoplasmic reticulum protein 1

acts_upstream_of_or_within

MGI:3652355 (PMID:16415102)

PMID:16415102

NCBI chr 2:142,757,254...142,761,243
Ensembl chr 2:142,757,270...142,761,116

sirtuin 3

RGD

NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808

Sirt6

sirtuin 6

involved_in

(MGI:6101624|PMID:27457971)

PMID:27457971

MGI:6101624

NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914

Slc30a8

solute carrier family 30 member 8

involved_in

PMID:19479076

BHF-UCL

PMID:19479076

RGD:2315022

NCBI chr 7:83,591,993...83,627,786
Ensembl chr 7:83,591,993...83,626,305

Snap25

synaptosome associated protein 25

IEP

RGD

PMID:15042624

RGD:1581081

NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760

Sox4

SRY-box transcription factor 4

involved_in

(MGI:3819280|PMID:18477811)

PMID:18477811

MGI:3819280

NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665

Stim1

stromal interaction molecule 1

involved_in

MGI:5008476 (PMID:18452988), (PMID:30131394), (PMID:31664108)

PMID:18452988 PMID:30131394 PMID:31664108

NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363

Tardbp

TAR DNA binding protein

RGD

PMID:21127054

RGD:7243008

NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055

Tcf7l2

transcription factor 7 like 2

involved_in

(PMID:19386626)
(MGI:4412432|PMID:19168596)

PMID:19168596 PMID:19386626

MGI:4412432

NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967

Tm7sf3

transmembrane 7 superfamily member 3

involved_in

(PMID:21853325)
GO_REF:0000024

PMID:21853325

GO_REF:0000024

NCBI chr 4:179,518,127...179,550,154
Ensembl chr 4:179,518,130...179,550,154

Trh

thyrotropin releasing hormone

involved_in

IDA
IBA

GO_REF:0000033

PMID:16118471

GO_REF:0000033, RGD:1600419

NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637

Trpm2

transient receptor potential cation channel, subfamily M, member 2

RGD

PMID:16601673

RGD:9999436

NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181

urocortin 3

RGD

NCBI chr17:66,309,748...66,315,996
Ensembl chr17:66,309,371...66,315,990

positive regulation of insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abcc8

ATP binding cassette subfamily C member 8

involved_in

MGI:2388392 (PMID:16924481)

PMID:16924481

NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510

Abcg1

ATP binding cassette subfamily G member 1

RGD

PMID:29540530

RGD:41404656

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

Adcy8

adenylate cyclase 8

involved_in

ISS
IMP
IEA
ISO

GO_REF:0000024
PMID:21046358
GO_REF:0000107
(MGI:5636119|PMID:25403481)

PMID:25403481 PMID:21046358

GO_REF:0000024 GO_REF:0000107 MGI:5636119, RGD:8553299

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

Ano1

anoctamin 1

involved_in

UniProtKB:P13569 (PMID:24885604)
(MGI:5640937|PMID:24885604)

PMID:24885604

MGI:5640937

NCBI chr 1:199,751,439...199,900,099
Ensembl chr 1:199,751,439...199,900,069

Arrb1

arrestin, beta 1

involved_in

(MGI:4453294|PMID:19915011)

PMID:19915011

MGI:4453294

NCBI chr 1:153,837,964...153,912,111
Ensembl chr 1:153,838,078...153,904,061

Atg7

autophagy related 7

acts_upstream_of_or_within

MGI:3587769 (PMID:24105478)

PMID:24105478

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

Bad

BCL2-associated agonist of cell death

involved_in

(MGI:3778846|PMID:18223655)
GO_REF:0000107

PMID:18223655

GO_REF:0000107 MGI:3778846

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

Baiap3

BAI1-associated protein 3

involved_in

(PMID:28626000)

PMID:28626000

NCBI chr10:14,260,269...14,273,019
Ensembl chr10:14,260,269...14,273,019

C1qtnf12

C1q and TNF related 12

acts_upstream_of_or_within

(PMID:22275362)

PMID:22275362

NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003

C2cd2l

C2CD2-like

involved_in
acts_upstream_of_or_within

(PMID:28209843)
(PMID:24012759)
GO_REF:0000033

PMID:24012759 PMID:28209843

GO_REF:0000033

NCBI chr 8:44,648,074...44,658,856
Ensembl chr 8:44,648,079...44,658,340

Cacna1d

calcium voltage-gated channel subunit alpha1 D

RGD

PMID:23229155

RGD:13506727

NCBI chr16:5,227,157...5,521,163
Ensembl chr16:5,228,306...5,668,215

Camk2n1

calcium/calmodulin-dependent protein kinase II inhibitor 1

RGD

PMID:31327268

RGD:18899561

NCBI chr 5:150,674,819...150,676,600
Ensembl chr 5:150,673,507...150,676,600

Camk2n1^em1Tja

calcium/calmodulin-dependent protein kinase II inhibitor 1; ZFN induced mutant 1, Tja

RGD

CF transmembrane conductance regulator

involved_in

UniProtKB:Q5XXA6 (PMID:24885604)
(MGI:5640937|PMID:24885604)
GO_REF:0000107

PMID:24885604

GO_REF:0000107 MGI:5640937

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

Crh

corticotropin releasing hormone

RGD

PMID:20080775

RGD:5508172

NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919

Dynll1

dynein light chain LC8-type 1

RGD

PMID:17130471

RGD:1642149

NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741

Fto

FTO, alpha-ketoglutarate dependent dioxygenase

RGD

PMID:29890211

RGD:329951007

NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083

Gcg

glucagon

involved_in

IEA
IBA
ISO

GO_REF:0000107
GO_REF:0000033
(MGI:4453294|PMID:19915011)

Ensembl
GO_Central
RGD

PMID:19915011

GO_REF:0000033 GO_REF:0000107 MGI:4453294

NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929

ghrelin and obestatin prepropeptide

RGD

PMID:16647196

RGD:12905046

NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621

Gpld1

glycosylphosphatidylinositol specific phospholipase D1

involved_in

GO_REF:0000024
(MGI:5448527|PMID:20153004)

PMID:20153004

GO_REF:0000024 MGI:5448527

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

Gpr27

G protein-coupled receptor 27

acts_upstream_of_or_within

(PMID:22253604)

PMID:22253604

NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497

G protein-coupled receptor 39

acts_upstream_of_or_within

MGI:3701833 (PMID:19213833)

PMID:19213833

NCBI chr13:37,115,258...37,327,312
Ensembl chr13:37,115,102...37,328,267

Gpr68

G protein-coupled receptor 68

acts_upstream_of_or_within

MGI:5445001 (PMID:22733973)

PMID:22733973

NCBI chr 6:120,135,620...120,166,089
Ensembl chr 6:120,135,436...120,166,089

Hcfc1

host cell factor C1

involved_in

PMID:24250814

UniProt

PMID:24250814

RGD:151356618

NCBI chr X:151,687,779...151,712,688
Ensembl chr X:151,687,779...151,712,638

Hif1a

hypoxia inducible factor 1 subunit alpha

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2677892 (PMID:20440072)

PMID:20440072

GO_REF:0000107

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

Kif5b

kinesin family member 5B

RGD

PMID:25462067

RGD:11059539

NCBI chr17:51,489,904...51,527,508
Ensembl chr17:51,489,944...51,527,508

leptin receptor

RGD

NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908

Lrp1

LDL receptor related protein 1

RGD

PMID:24865476

RGD:13800516

NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910

Mpc2

mitochondrial pyruvate carrier 2

acts_upstream_of_or_within

MGI:5635078 (PMID:24910426)

PMID:24910426

NCBI chr13:77,728,176...77,747,664
Ensembl chr13:77,728,250...77,747,664

Myh9

myosin, heavy chain 9

RGD

PMID:23354122

RGD:12798521

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

NAD kinase

RGD

NCBI chr 5:166,145,708...166,176,328
Ensembl chr 5:166,145,481...166,176,322

Ncoa6

nuclear receptor coactivator 6

RGD

PMID:16738321

RGD:9590126

NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268

Nr1h4

nuclear receptor subfamily 1, group H, member 4

involved_in

(MGI:4457989|PMID:20447400)
GO_REF:0000107

PMID:20447400

GO_REF:0000107 MGI:4457989

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

Osbp

oxysterol binding protein

RGD

PMID:29540530

RGD:41404656

NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506

Oxct1

3-oxoacid CoA transferase 1

RGD

PMID:20460097

RGD:2326185

NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714

Pdx1

pancreatic and duodenal homeobox 1

acts_upstream_of_or_within

(PMID:22253604)

PMID:22253604

NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064

Pla2g6

phospholipase A2 group VI

involved_in

IDA
IEA
ISO

GO_REF:0000107
(MGI:3778607|PMID:17895289)

PMID:17895289 PMID:11278673

GO_REF:0000107 MGI:3778607, RGD:6482760

NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114

Ppard

peroxisome proliferator-activated receptor delta

RGD

PMID:19965574

RGD:2324877

NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968

Ppp3cb

protein phosphatase 3 catalytic subunit beta

involved_in

IMP
IEA
ISO

PMID:11978799
GO_REF:0000107
(MGI:5306323|PMID:11978799)

PMID:11978799 PMID:11978799

GO_REF:0000107 MGI:5306323, RGD:8553382

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

Prkn

parkin RBR E3 ubiquitin protein ligase

RGD

PMID:24096089

RGD:10413842

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

Rac1

Rac family small GTPase 1

involved_in

IMP
ISO

(MGI:5489045|PMID:23412604)

PMID:23412604 PMID:23412604

MGI:5489045, RGD:14392803

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

Rfx6

regulatory factor X, 6

involved_in

(PMID:25497100)

PMID:25497100

NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147

RT1-Db1

RT1 class II, locus Db1

involved_in

(PMID:21484216)

PMID:21484216

NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258

sirtuin 1

RGD

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

Slc2a2

solute carrier family 2 member 2

involved_in

GO_REF:0000107
MGI:2181752 (PMID:10823833), (PMID:10969832)

PMID:10823833 PMID:10969832

GO_REF:0000107

NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933

Sri

sorcin

involved_in

(MGI:5487506|PMID:22338092)

PMID:22338092

MGI:5487506

NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077

Stx4

syntaxin 4

involved_in

(PMID:12855681), (PMID:24552216)

PMID:12855681 PMID:24552216

NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979

syntabulin

RGD

NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828

Trpa1

transient receptor potential cation channel, subfamily A, member 1

RGD

PMID:22701540

RGD:10043784

NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570

Trpm4

transient receptor potential cation channel, subfamily M, member 4

RGD

PMID:16806463

RGD:10003029

NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532

Trpm5

transient receptor potential cation channel, subfamily M, member 5

involved_in

IEA

GO_REF:0000107

Ensembl

GO_REF:0000107

NCBI chr 1:198,254,956...198,277,824
Ensembl chr 1:198,255,723...198,277,654

Tunar

TCL1 upstream neural differentiation-associated RNA

involved_in

(PMID:34513312)

PMID:34513312

NCBI chr 6:124,245,949...124,293,440

Vsnl1

visinin-like 1

acts_upstream_of_or_within

(PMID:16731532)

PMID:16731532

NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479

positive regulation of peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Fga

fibrinogen alpha chain

involved_in

(PMID:19193866)

PMID:19193866

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

Fgb

fibrinogen beta chain

involved_in

(PMID:19193866)

PMID:19193866

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

Fgg

fibrinogen gamma chain

involved_in

(PMID:19193866)

PMID:19193866

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

Grp

gastrin releasing peptide

involved_in

GO_REF:0000024
(PMID:496973)

PMID:496973

GO_REF:0000024

NCBI chr18:59,388,679...59,402,061
Ensembl chr18:59,388,274...59,402,061

Hfe

homeostatic iron regulator

involved_in

(PMID:21173098)

PMID:21173098

NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502

Ildr1

immunoglobulin-like domain containing receptor 1

acts_upstream_of_or_within

(PMID:23863714)

PMID:23863714

NCBI chr11:64,085,774...64,118,760
Ensembl chr11:64,008,566...64,118,760

Prkd1

protein kinase D1

Atrial natriuretic factor

RGD

PMID:16648482

RGD:243065275

NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042

Rasl10b

RAS-like, family 10, member B

involved_in

(MGI:5437436|PMID:17984325)

PMID:17984325

MGI:5437436

NCBI chr10:68,209,761...68,222,118
Ensembl chr10:68,210,275...68,220,376

Spink1

serine peptidase inhibitor, Kazal type 1

RGD

PMID:2755938

RGD:10044250

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

Tfr2

transferrin receptor 2

involved_in

(PMID:21173098)

PMID:21173098

NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591

positive regulation of prolactin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abat

4-aminobutyrate aminotransferase

RGD

PMID:4043235

RGD:10046063

NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835

Egfr

epidermal growth factor receptor

RGD

PMID:6195656

RGD:10395255

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

microRNA 222

RGD

NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006

microRNA 9

RGD

NCBI chr 9:1,080,274...1,080,383
Ensembl chr 9:1,080,274...1,080,383

Nmu

neuromedin U

involved_in

PMID:28874765

UniProt

PMID:28874765

RGD:13461758

NCBI chr14:31,844,564...31,872,196
Ensembl chr14:31,844,728...31,872,192

positive regulation of somatostatin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Adcyap1

adenylate cyclase activating polypeptide 1

RGD

PMID:17660849

RGD:2325283

NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773

Cckar

cholecystokinin A receptor

RGD

PMID:19959964

RGD:4110825

NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747

Cckbr

cholecystokinin B receptor

RGD

PMID:19959964

RGD:4110825

NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881

Gal

galanin and GMAP prepropeptide

involved_in

(PMID:8837218)

NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959

Npy

neuropeptide Y

involved_in

(PMID:8837218)

NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495

Sct

secretin

involved_in

IDA
IBA

GO_REF:0000033

PMID:11123201

GO_REF:0000033, RGD:9590235

NCBI chr 1:196,382,857...196,383,668
Ensembl chr 1:196,382,856...196,383,658

positive regulation of substance P secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptger3

prostaglandin E receptor 3

RGD

NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434

Ptger4

prostaglandin E receptor 4

RGD

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

positive regulation of substance P secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ptger4

prostaglandin E receptor 4

RGD

PMID:15292051

RGD:10003094

NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670

positive regulation of thyroid-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

sirtuin 1

RGD

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

prolactin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A1

RGD

NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343

Tacr2

tachykinin receptor 2

RGD

PMID:9376629

RGD:5147487

NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446

Ube2q1

ubiquitin conjugating enzyme E2 Q1

acts_upstream_of_or_within

MGI:5486217 (PMID:23108111)

PMID:23108111

NCBI chr 2:175,198,793...175,209,152
Ensembl chr 2:175,198,873...175,207,942

Vip

vasoactive intestinal peptide

involved_in

ISS

GO_REF:0000024

AgBase

GO_REF:0000024

NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216

regulation of corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Avpr1a

arginine vasopressin receptor 1A

involved_in

NAS

PMID:1560825

UniProt

PMID:1560825

RGD:1298691

NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215

Crhbp

corticotropin releasing hormone binding protein

involved_in

(PMID:13150566)
GO_REF:0000024

PMID:13150566

GO_REF:0000024

NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710

regulation of corticotropin-releasing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Htr2c

5-hydroxytryptamine receptor 2C

involved_in

GO_REF:0000024
(MGI:3716046|PMID:17596444), (MGI:3798744|PMID:17451451)

PMID:17451451 PMID:17596444

GO_REF:0000024 MGI:3716046 MGI:3798744

NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287

regulation of glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Il6

interleukin 6

involved_in

GO_REF:0000024
(MGI:5304221|PMID:22037645)
(PMID:22037645)

PMID:22037645

GO_REF:0000024 MGI:5304221

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Pask

PAS domain containing serine/threonine kinase

involved_in

(MGI:4867563|PMID:21181396)

PMID:21181396

MGI:4867563

NCBI chr 9:93,844,275...93,886,036
Ensembl chr 9:93,844,278...93,885,111

Syt7

synaptotagmin 7

involved_in

GO_REF:0000024
(MGI:4848029|PMID:19171650)

PMID:19171650

GO_REF:0000024 MGI:4848029

NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026

regulation of growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Chd7

chromodomain helicase DNA binding protein 7

involved_in

(PMID:9556299)

PMID:9556299

NCBI chr 5:21,812,007...21,995,358
Ensembl chr 5:21,812,070...21,995,358

growth hormone secretagogue receptor

RGD

PMID:12045256

RGD:625699

NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865

Hmga2

high mobility group AT-hook 2

acts_upstream_of_or_within

MGI:1856426 (PMID:504232)

PMID:504232

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

regulation of insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Alox5

arachidonate 5-lipoxygenase

involved_in

GO_REF:0000024
(MGI:3803402|PMID:18421434)
GO_REF:0000107

PMID:18421434

GO_REF:0000024 GO_REF:0000107 MGI:3803402

NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743

Bmal1

basic helix-loop-helix ARNT like 1

involved_in

GO_REF:0000024
(MGI:4819446|PMID:20562852)

PMID:20562852

GO_REF:0000024 MGI:4819446

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

CART prepropeptide

RGD

NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713

Ccl5

C-C motif chemokine ligand 5

involved_in

(PMID:23979485)
GO_REF:0000024

PMID:23979485

GO_REF:0000024

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

Cela2a

chymotrypsin like elastase 2A

involved_in

(PMID:31358993)
GO_REF:0000024

PMID:31358993

GO_REF:0000024

NCBI chr 5:154,126,879...154,136,630
Ensembl chr 5:154,126,878...154,136,632

Clock

clock circadian regulator

involved_in

GO_REF:0000024
(MGI:4819446|PMID:20562852)
GO_REF:0000107

PMID:20562852

GO_REF:0000024 GO_REF:0000107 MGI:4819446

NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400

Cnr1

cannabinoid receptor 1

RGD

PMID:19644453

RGD:2314628

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

Cpt1a

carnitine palmitoyltransferase 1A

RGD

PMID:11988095

RGD:1298597

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

Eipr1

EARP complex and GARP complex interacting protein 1

involved_in

PMID:3172165

UniProt

PMID:3172165

RGD:25671404

NCBI chr 6:45,388,451...45,502,089
Ensembl chr 6:45,388,376...45,502,083

Ensa

endosulfine alpha

acts_upstream_of_or_within
involved_in

(PMID:9653196)
GO_REF:0000107

PMID:9653196

GO_REF:0000107

NCBI chr 2:183,185,552...183,192,888
Ensembl chr 2:183,185,552...183,194,847

G6pc2

glucose-6-phosphatase catalytic subunit 2

involved_in

(PMID:20668700)

PMID:20668700

NCBI chr 3:53,999,821...54,005,539

Gcg

glucagon

involved_in
acts_upstream_of_or_within

GO_REF:0000024
(PMID:14736883)
(MGI:5304221|PMID:22037645)

PMID:14736883 PMID:22037645

GO_REF:0000024 MGI:5304221

NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929

Gck

glucokinase

involved_in
acts_upstream_of_or_within

(PMID:20668700)
MGI:2177703 (PMID:8530440), (PMID:8954920)
GO_REF:0000033

PMID:8530440 PMID:8954920 PMID:20668700

GO_REF:0000033

NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995

Gip

gastric inhibitory polypeptide

TAS

RGD

PMID:8446620

RGD:632885

NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503

Hadh

hydroxyacyl-CoA dehydrogenase

involved_in

GO_REF:0000024
(MGI:4849622|PMID:20670938)

PMID:20670938

GO_REF:0000024 MGI:4849622

NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353

Hnf4a

hepatocyte nuclear factor 4, alpha

involved_in

(MGI:3575336|PMID:15761495)
GO_REF:0000107

PMID:15761495

GO_REF:0000107 MGI:3575336

NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320

Ifng

interferon gamma

involved_in

(PMID:8383325)

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

Il1b

interleukin 1 beta

involved_in

(PMID:8383325)

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

Il6

interleukin 6

involved_in

GO_REF:0000024
(MGI:5304221|PMID:22037645)
(PMID:22037645)

PMID:22037645

GO_REF:0000024 MGI:5304221

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

Kcnj11

potassium inwardly-rectifying channel, subfamily J, member 11

involved_in

(PMID:15115830)

PMID:15115830

NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082

Lep

leptin

acts_upstream_of_or_within

MGI:1856424 (PMID:16513828)

PMID:16513828

NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262

Mtnr1b

melatonin receptor 1B

involved_in

(PMID:20668700)

PMID:20668700

NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737

Nos2

nitric oxide synthase 2

involved_in

(PMID:8383325)
GO_REF:0000107

GO_REF:0000107

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

Pde3b

phosphodiesterase 3B

acts_upstream_of_or_within

(PMID:14736883)

PMID:14736883

NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334

Per2

period circadian regulator 2

involved_in

GO_REF:0000024
(MGI:5319572|PMID:22504074)

PMID:22504074

GO_REF:0000024 MGI:5319572

NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459

Pick1

protein interacting with PRKCA 1

involved_in

(PMID:29768204)

PMID:29768204

NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848

Ppp3cb

protein phosphatase 3 catalytic subunit beta

involved_in

PMID:11978799

UniProt

PMID:11978799

RGD:8553382

NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981

Rfx3

regulatory factor X3

involved_in

(MGI:3713191|PMID:17229940), (MGI:4941444|PMID:20413507)

PMID:17229940 PMID:20413507

MGI:3713191 MGI:4941444

NCBI chr 1:225,449,872...225,709,622
Ensembl chr 1:225,456,187...225,709,402

Rfx6

regulatory factor X, 6

involved_in

(PMID:20148032)
(MGI:4422104|PMID:20148032)

PMID:20148032

MGI:4422104

NCBI chr20:31,019,784...31,073,266
Ensembl chr20:31,019,829...31,073,147

Slc16a1

solute carrier family 16 member 1

involved_in

(MGI:5465432|PMID:22522610)

PMID:22522610

MGI:5465432

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

Slc25a22

solute carrier family 25 member 22

involved_in

PMID:19584051

UniProt

PMID:19584051

RGD:151665733

NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331

Slc8b1

solute carrier family 8 member B1

involved_in

(PMID:23056385)
GO_REF:0000024

PMID:23056385

GO_REF:0000024

NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031

Srebf1

sterol regulatory element binding transcription factor 1

acts_upstream_of_or_within

MGI:2177958 (PMID:18178930)

PMID:18178930

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

Sstr5

somatostatin receptor 5

involved_in
acts_upstream_of_or_within

IBA
ISO

GO_REF:0000033
MGI:3584184 (PMID:15919085)

PMID:15919085

GO_REF:0000033

NCBI chr10:14,506,868...14,512,946
Ensembl chr10:14,506,868...14,512,946

Syt7

synaptotagmin 7

involved_in

IMP
ISO
ISS

(MGI:3773625|PMID:18308938)
GO_REF:0000024

PMID:18308938 PMID:17709608

GO_REF:0000024 MGI:3773625, RGD:2311143

NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026

Syt7_v1

synaptotagmin 7, variant 1

RGD

synaptotagmin 9

RGD

NCBI chr 1:161,275,882...161,456,384
Ensembl chr 1:161,275,734...161,455,007

Tcirg1

T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3

acts_upstream_of_or_within

MGI:1856973 (PMID:17046993)

PMID:17046993

NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742

Tfap2b

transcription factor AP-2 beta

involved_in

(PMID:15940393), (PMID:19325541)
GO_REF:0000024

PMID:15940393 PMID:19325541

GO_REF:0000024

NCBI chr 9:21,786,251...21,816,054
Ensembl chr 9:21,786,258...21,814,520

Tnf

tumor necrosis factor

involved_in

(PMID:8383325)

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

involved_in

GO_REF:0000024
(MGI:5520038|PMID:22363741)

PMID:22363741

GO_REF:0000024 MGI:5520038

NCBI chr20:5,202,837...5,214,541
Ensembl chr20:5,202,837...5,214,164

regulation of insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Abca12

ATP binding cassette subfamily A member 12

involved_in

(MGI:6394227|PMID:32072744)

PMID:32072744

MGI:6394227

NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049

Adcy5

adenylate cyclase 5

involved_in

GO_REF:0000024
GO_REF:0000107
(PMID:24740569)

PMID:24740569

GO_REF:0000024 GO_REF:0000107

NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974

Birc5

baculoviral IAP repeat-containing 5

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:3046203 (PMID:19644667)

PMID:19644667

GO_REF:0000107

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

Brsk2

BR serine/threonine kinase 2

involved_in

GO_REF:0000107
(MGI:5448801|PMID:22798068)
(PMID:22669945)

PMID:22669945 PMID:22798068

GO_REF:0000107 MGI:5448801

NCBI chr 1:197,035,505...197,088,624
Ensembl chr 1:197,035,633...197,088,092

Cacna1e

calcium voltage-gated channel subunit alpha1 E

acts_upstream_of_or_within

MGI:3526823 (PMID:11923483), (PMID:15630454)

PMID:11923483 PMID:15630454

NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450

Cdk16

cyclin-dependent kinase 16

involved_in

IEA
ISS
ISO

GO_REF:0000107
GO_REF:0000024
(MGI:5448801|PMID:22798068)
(PMID:22798068)

Ensembl
UniProt
RGD

PMID:22798068

GO_REF:0000024 GO_REF:0000107 MGI:5448801

NCBI chr X:1,492,814...1,504,309
Ensembl chr X:1,492,814...1,504,148

Ddrgk1

DDRGK domain containing 1

NOT|involved_in

PMID:21494687

ParkinsonsUK-UCL

PMID:21494687

RGD:11567254

NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680

Efna5

ephrin A5

involved_in

GO_REF:0000024
(MGI:5294297|PMID:17448994)

PMID:17448994

GO_REF:0000024 MGI:5294297

NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413

Epha5

EPH receptor A5

involved_in

GO_REF:0000024
(MGI:5294297|PMID:17448994)

PMID:17448994

GO_REF:0000024 MGI:5294297

NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317

Foxa2

forkhead box A2

involved_in

(MGI:5142372|PMID:11875061)

PMID:11875061

MGI:5142372

NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326

Hmgn3

high mobility group nucleosomal binding domain 3

acts_upstream_of_or_within

MGI:4366465 (PMID:19651901)

PMID:19651901

NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976

Lrp5

LDL receptor related protein 5

acts_upstream_of_or_within

MGI:2448955 (PMID:12509515)

PMID:12509515

NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581

Mir130a

microRNA 130a

acts_upstream_of_or_within

(PMID:20417623)

PMID:20417623

NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629

Mir200a

microRNA 200a

acts_upstream_of_or_within

(PMID:20417623)

PMID:20417623

NCBI chr 5:166,648,494...166,648,582

Mir410

microRNA 410

acts_upstream_of_or_within

(PMID:20417623)

PMID:20417623

NCBI chr 6:128,758,358...128,758,433
Ensembl chr 6:128,758,354...128,758,434

Myt1

myelin transcription factor 1

acts_upstream_of_or_within

(PMID:17928203)

PMID:17928203

NCBI chr 3:168,890,466...168,950,341
Ensembl chr 3:168,886,089...168,950,341

Nr1d1

nuclear receptor subfamily 1, group D, member 1

involved_in

GO_REF:0000107
(MGI:5313784|PMID:22166979)
GO_REF:0000024

PMID:22166979

GO_REF:0000024 GO_REF:0000107 MGI:5313784

NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705

Nr1h4

nuclear receptor subfamily 1, group H, member 4

involved_in

(PMID:20447400)

PMID:20447400

NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047

Piwil4

piwi-like RNA-mediated gene silencing 4

involved_in

PMID:28711973

UniProt

PMID:28711973

RGD:13800537

NCBI chr 8:11,536,520...11,579,883
Ensembl chr 8:11,536,520...11,579,761

Prkce

protein kinase C, epsilon

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:2680163 (PMID:19401415)

PMID:19401415

GO_REF:0000107

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

Sidt2

SID1 transmembrane family, member 2

involved_in
acts_upstream_of_or_within

GO_REF:0000107
MGI:5532825 (PMID:23776622)

PMID:23776622

GO_REF:0000107

NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700

Slc9b2

solute carrier family 9 member B2

involved_in

(MGI:5492253|PMID:23720317)

PMID:23720317

MGI:5492253

NCBI chr 2:223,726,982...223,761,234
Ensembl chr 2:223,736,354...223,761,225

Stxbp4

syntaxin binding protein 4

involved_in

(PMID:12855681)
GO_REF:0000033

PMID:12855681

GO_REF:0000033

NCBI chr10:75,301,868...75,458,741
Ensembl chr10:75,305,463...75,458,663

Sybu

syntabulin

acts_upstream_of_or_within

PMID:22975310

MGI

PMID:22975310

RGD:8554225

NCBI chr 7:75,847,000...75,948,919
Ensembl chr 7:75,847,003...75,948,828

Tcf7l2

transcription factor 7 like 2

acts_upstream_of_or_within

(PMID:19168596)

PMID:19168596

NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967

Tiam1

TIAM Rac1 associated GEF 1

RGD

PMID:18930714

RGD:10043296

NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901

Ufm1

ubiquitin-fold modifier 1

NOT|involved_in

PMID:21494687

ParkinsonsUK-UCL

PMID:21494687

RGD:11567254

NCBI chr 2:137,969,476...137,977,620
Ensembl chr 2:137,966,678...137,978,089
Ensembl chr 2:137,966,678...137,978,089

Zbed6

zinc finger, BED-type containing 6

involved_in

(MGI:6120647|PMID:29440408)

PMID:29440408

MGI:6120647

NCBI chr13:45,107,253...45,113,524
Ensembl chr13:45,071,718...45,114,009

regulation of peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Ffar2

free fatty acid receptor 2

involved_in

GO_REF:0000024
(MGI:5461989|PMID:22190648), (MGI:5574283|PMID:23589301)

PMID:22190648 PMID:23589301

GO_REF:0000024 MGI:5461989 MGI:5574283

NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033

Ffar3

free fatty acid receptor 3

involved_in

GO_REF:0000024
(MGI:5461989|PMID:22190648)

PMID:22190648

GO_REF:0000024 MGI:5461989

NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849

Hmga2

high mobility group AT-hook 2

acts_upstream_of_or_within

MGI:1856426 (PMID:504232)

PMID:504232

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

Tp53

tumor protein p53

involved_in

(PMID:18703674)

PMID:18703674

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

regulation of somatostatin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Cacna1e

calcium voltage-gated channel subunit alpha1 E

acts_upstream_of_or_within

MGI:3526823 (PMID:17369816)

PMID:17369816

NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450

regulation of thyroid-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Pax8

paired box 8

involved_in

GO_REF:0000024
(PMID:15356023)

PMID:15356023

GO_REF:0000024

NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363

somatostatin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CART prepropeptide

RGD

NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713

Npff

neuropeptide FF-amide peptide precursor

RGD

PMID:1704109

RGD:2316580

NCBI chr 7:133,654,530...133,655,319

thyroid-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Slc16a10

solute carrier family 16 member 10

acts_upstream_of_or_within_negative_effect

MGI:1203732 (PMID:24248460)

PMID:24248460

NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839

Slc16a2

solute carrier family 16 member 2

acts_upstream_of_or_within_negative_effect

MGI:1919722|MGI:3710233 (PMID:24248460)

PMID:24248460

NCBI chr X:68,725,365...68,848,572
Ensembl chr X:68,723,261...68,848,771

vasopressin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

Agt

angiotensinogen

acts_upstream_of_or_within

MGI:2136636 (PMID:9557921)

PMID:9557921

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

Ecrg4

ECRG4 augurin precursor

involved_in

UniProtKB:D4A540-PRO_0000415564 (PMID:20233222)

PMID:20233222

NCBI chr 9:45,992,954...46,012,605
Ensembl chr 9:45,992,954...46,012,595

Npff

neuropeptide FF-amide peptide precursor

RGD

PMID:8612481

RGD:2316572

NCBI chr 7:133,654,530...133,655,319

Tor2a

torsin family 2, member A

involved_in

(PMID:12910263)

PMID:12910263

NCBI chr 3:16,048,591...16,053,198
Ensembl chr 3:16,048,549...16,052,634

Trpv4

transient receptor potential cation channel, subfamily V, member 4

acts_upstream_of_or_within

MGI:2667379 (PMID:12777254)