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ONTOLOGY REPORT - ANNOTATIONS

Term:muscle filament sliding
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Accession:GO:0030049 term browser browse the term
Definition:The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.


show annotations for term's descendants           Sort by:
muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102551071 myosin light polypeptide 6-like involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813 NCBI chr13:9,903,286...9,903,991 JBrowse link
G Myh6 myosin heavy chain 6 involved_in IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:16088376)		 Ensembl
GO_Central
RGD		 PMID:16088376 GO_REF:0000033 GO_REF:0000107 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myh7 myosin heavy chain 7 involved_in ISO
IBA
IEA		 (PMID:16088376), (PMID:8514894)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:8514894 PMID:16088376 GO_REF:0000033 GO_REF:0000107 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Myh8 myosin heavy chain 8 involved_in ISO
IEA		 (PMID:17041932)
GO_REF:0000107		 RGD
Ensembl		 PMID:17041932 GO_REF:0000107 NCBI chr10:51,963,510...51,993,103
Ensembl chr10:51,963,510...51,993,232 		JBrowse link
G Myl6 myosin light chain 6 involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813 NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791 		JBrowse link
G Myl6l2 myosin light chain 6 like 2 involved_in TAS PMID:2304459 HGNC-UCL PMID:2304459 RGD:8554813 NCBI chr12:29,488,091...29,488,746
Ensembl chr12:29,488,256...29,488,711 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in ISO
IEA
ISS		 (PMID:12186860), (PMID:15923195)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:12186860 PMID:15923195 GO_REF:0000024 GO_REF:0000107 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tpm1 tropomyosin 1 involved_in IDA PMID:11136687 BHF-UCL PMID:11136687 RGD:1556479 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
negative regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dbn1 drebrin 1 IDA RGD PMID:17543276 RGD:10398727 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
regulation of muscle filament sliding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mylk2 myosin light chain kinase 2 involved_in ISO
IEA		 (PMID:16448786)
GO_REF:0000107		 RGD
Ensembl		 PMID:16448786 GO_REF:0000107 NCBI chr 3:141,376,450...141,388,357
Ensembl chr 3:141,376,691...141,387,728 		JBrowse link
regulation of muscle filament sliding speed term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnnc1 troponin C1, slow skeletal and cardiac type involved_in ISO (PMID:10747195) RGD PMID:10747195 NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634 		JBrowse link
G Tnnt2 troponin T2, cardiac type involved_in IMP PMID:10747195 BHF-UCL PMID:10747195 RGD:8554013 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20076
    multicellular organismal process 8906
      system process 3539
        muscle system process 486
          muscle contraction 345
            muscle filament sliding 11
              negative regulation of muscle filament sliding 1
              positive regulation of muscle filament sliding 0
              regulation of muscle filament sliding + 4
Path 2
Term Annotations click to browse term
  biological_process 20076
    cellular process 19155
      actin filament-based process 856
        actin filament-based movement 129
          actin-mediated cell contraction 105
            actin-myosin filament sliding 12
              muscle filament sliding 11
                negative regulation of muscle filament sliding 1
                positive regulation of muscle filament sliding 0
                regulation of muscle filament sliding + 4
paths to the root