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ONTOLOGY REPORT - ANNOTATIONS


Term:actin filament polymerization
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Accession:GO:0030041 term browser browse the term
Definition:Assembly of actin filaments by the addition of actin monomers to a filament.
Synonyms:exact_synonym: actin polymerization
 related_synonym: actin polymerizing activity


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actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase ISO RGD PMID:17615370 RGD:8693596 NCBI chr 1:270,761,641...270,906,708
Ensembl chr 1:270,761,668...270,906,711
JBrowse link
G AIF1 allograft inflammatory factor 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 7:23,711,752...23,731,191
Ensembl chr 7:23,711,722...23,731,671
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 involved_in IEA InterPro
UniProt
GO_REF:0000002 GO_REF:0000104 NCBI chr13:66,075,926...66,093,986
Ensembl chr13:66,055,364...66,100,310
JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:95,738,789...95,750,835
Ensembl chr 1:95,625,800...95,750,875
JBrowse link
G CATIP ciliogenesis associated TTC17 interacting protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:120,419,473...120,425,441
Ensembl chr15:120,419,473...120,425,439
JBrowse link
G COBL cordon-bleu WH2 repeat protein involved_in ISO (MGI:3765263|PMID:17956734) BHF-UCL PMID:17956734 MGI:3765263 NCBI chr 9:136,850,521...137,055,249 JBrowse link
G CTTN cortactin involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,102...3,060,855
JBrowse link
G DIAPH1 diaphanous related formin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3034135|PMID:14992721) InterPro
MGI
PMID:14992721 GO_REF:0000002 MGI:3034135 NCBI chr 2:143,158,691...143,271,110
Ensembl chr 2:143,158,584...143,271,147
JBrowse link
G DIAPH2 diaphanous related formin 2 acts_upstream_of_or_within ISO (MGI:3034135|PMID:14992721) MGI PMID:14992721 MGI:3034135 NCBI chr  X:78,602,385...79,520,441
Ensembl chr  X:78,602,390...79,520,428
JBrowse link
G DIAPH3 diaphanous related formin 3 involved_in ISO (MGI:6201827|PMID:23558171) UniProt PMID:23558171 MGI:6201827 NCBI chr11:32,492,735...32,994,854
Ensembl chr11:32,492,740...32,994,837
JBrowse link
G FAM107A family with sequence similarity 107 member A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:40,276,896...40,369,708 JBrowse link
G GAS7 growth arrest specific 7 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:2159085|PMID:11795944)
GO_Central
MGI
PMID:11795944 PMID:21873635 MGI:2159085 NCBI chr12:54,752,436...54,974,535
Ensembl chr12:54,752,507...54,973,515
JBrowse link
G GSN gelsolin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287
JBrowse link
G GSN gelsolin involved_in ISS UniProt GO_REF:0000024
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,142...138,906,351
JBrowse link
G LMOD2 leiomodin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,661...23,812,481
JBrowse link
G MICALL2 MICAL like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:951,330...971,129
Ensembl chr 3:951,323...971,111
JBrowse link
G MSRB1 methionine sulfoxide reductase B1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr 3:40,017,161...40,021,736
Ensembl chr 3:40,017,194...40,028,047
JBrowse link
G MSRB2 methionine sulfoxide reductase B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:51,888,828...51,910,725
Ensembl chr10:51,888,817...51,910,392
JBrowse link
G MTSS1 MTSS I-BAR domain containing 1 acts_upstream_of_or_within ISO (MGI:2651741|PMID:12482861) MGI PMID:12482861 MGI:2651741 NCBI chr 4:14,933,290...15,103,256
Ensembl chr 4:14,933,324...15,105,406
JBrowse link
G MYH9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chr 5:11,365,603...11,456,475 JBrowse link
G PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:57,100,212...57,145,278
Ensembl chr 7:57,102,756...57,146,754
JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (MGI:5468414|PMID:22750946) MGI PMID:22750946 MGI:5468414 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687
JBrowse link
G SPIRE1 spire type actin nucleation factor 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:96,934,023...97,114,591
Ensembl chr 6:96,934,265...97,114,588
JBrowse link
G SPIRE2 spire type actin nucleation factor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:211,480...246,109
Ensembl chr 6:211,487...243,636
JBrowse link
G TTC17 tetratricopeptide repeat domain 17 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:18,807,521...18,954,667
Ensembl chr 2:18,807,523...18,954,650
JBrowse link
G VIL1 villin 1 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:2387810|PMID:12147689) Ensembl
MGI
PMID:12147689 GO_REF:0000107 MGI:2387810 NCBI chr  X:42,774,597...42,793,055
Ensembl chr  X:42,774,588...42,793,055
JBrowse link
G WASHC3 WASH complex subunit 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:82,155,253...82,259,552
Ensembl chr 5:82,155,256...82,316,190
JBrowse link
G WASHC5 WASH complex subunit 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:14,598,133...14,667,535
Ensembl chr 4:14,598,148...14,668,327
JBrowse link
G WASL WASP like actin nucleation promoting factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506
JBrowse link
'de novo' actin filament nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G JMY junction mediating and regulatory protein, p53 cofactor involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:88,021,572...88,098,522
Ensembl chr 2:88,022,709...88,089,426
JBrowse link
actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in ISO (PMID:19666531)
(MGI:5619440|PMID:23325791)
UniProt PMID:19666531 PMID:23325791 MGI:5619440 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287
JBrowse link
G MYH9 myosin heavy chain 9 NOT|involved_in ISO (MGI:5619440|PMID:23325791) UniProt PMID:23325791 MGI:5619440 NCBI chr 5:11,365,603...11,456,475 JBrowse link
G RDX radixin involved_in IEA UniProt GO_REF:0000043 NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,441...38,376,439
JBrowse link
G SCIN scinderin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745
JBrowse link
G SPTA1 spectrin alpha, erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 4:91,573,470...91,640,057
Ensembl chr 4:91,485,067...91,640,063
JBrowse link
G SPTAN1 spectrin alpha, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000043 NCBI chr 1:268,936,120...269,002,261
Ensembl chr 1:268,936,025...269,002,261
JBrowse link
G SPTB spectrin beta, erythrocytic involved_in IEA UniProt GO_REF:0000104 NCBI chr 7:88,812,717...88,954,471
Ensembl chr 7:88,812,715...88,954,306
JBrowse link
G SPTBN1 spectrin beta, non-erythrocytic 1 involved_in IEA UniProt GO_REF:0000104 NCBI chr 3:86,585,225...86,784,316
Ensembl chr 3:86,585,050...86,784,107
JBrowse link
G SPTBN2 spectrin beta, non-erythrocytic 2 involved_in IEA UniProt GO_REF:0000104 NCBI chr 2:5,683,414...5,739,418
Ensembl chr 2:5,695,858...5,739,417
JBrowse link
G SPTBN4 spectrin beta, non-erythrocytic 4 involved_in IEA UniProt GO_REF:0000043 NCBI chr 6:48,729,839...48,812,799
Ensembl chr 6:48,729,750...48,812,796
JBrowse link
G TPM1 tropomyosin 1 ISO RGD PMID:15779917 RGD:1600523 NCBI chr 1:108,986,981...109,016,090
Ensembl chr 1:108,986,981...109,019,440
JBrowse link
G VIL1 villin 1 involved_in ISS
IEA
UniProt GO_REF:0000024 GO_REF:0000043 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EVL Enah/Vasp-like involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:120,911,814...121,056,556
Ensembl chr 7:120,911,220...121,056,558
JBrowse link
G FMN1 formin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,008,721
JBrowse link
G FMN2 formin 2 involved_in IEA InterPro GO_REF:0000002
G GSN gelsolin involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287
JBrowse link
G GSN gelsolin involved_in IEA InterPro GO_REF:0000002
G LMOD1 leiomodin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:24,165,293...24,194,823
Ensembl chr10:24,164,792...24,193,820
JBrowse link
G LMOD2 leiomodin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,661...23,812,481
JBrowse link
G LMOD3 leiomodin 3 involved_in ISO (PMID:25250574) UniProt PMID:25250574 NCBI chr13:50,541,407...50,554,346 JBrowse link
G SPIRE1 spire type actin nucleation factor 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 6:96,934,023...97,114,591
Ensembl chr 6:96,934,265...97,114,588
JBrowse link
G SPIRE2 spire type actin nucleation factor 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:211,480...246,109
Ensembl chr 6:211,487...243,636
JBrowse link
G VIL1 villin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR2 actin related protein 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 3:76,691,275...76,729,269
Ensembl chr 3:76,691,275...76,729,210
JBrowse link
G ACTR3 actin related protein 3 involved_in IEA
IBA
(PMID:21873635) InterPro
GO_Central
PMID:21873635 GO_REF:0000002 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,846...20,208,186
JBrowse link
G ARPC1A actin related protein 2/3 complex subunit 1A involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr 3:6,296,257...6,324,526
Ensembl chr 3:6,197,760...6,324,524
JBrowse link
G ARPC1B actin related protein 2/3 complex subunit 1B involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 3:6,329,737...6,342,641
Ensembl chr 3:6,220,939...6,342,637
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr14:31,814,382...31,823,452
Ensembl chr14:31,814,150...31,826,855
JBrowse link
G ARPC4 actin related protein 2/3 complex subunit 4 involved_in IEA InterPro
Ensembl
UniProt
GO_REF:0000002 GO_REF:0000104 GO_REF:0000107 NCBI chr13:66,075,926...66,093,986
Ensembl chr13:66,055,364...66,100,310
JBrowse link
G ARPC5 actin related protein 2/3 complex subunit 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:124,839,062...124,847,906
Ensembl chr 9:124,837,773...124,848,108
JBrowse link
G ARPC5L actin related protein 2/3 complex subunit 5 like involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:265,645,800...265,653,513
Ensembl chr 1:265,642,375...265,654,015
JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,294,423...85,633,645
Ensembl chr 2:85,294,434...85,636,317
JBrowse link
G JMY junction mediating and regulatory protein, p53 cofactor involved_in IEA InterPro GO_REF:0000002 NCBI chr 2:88,021,572...88,098,522
Ensembl chr 2:88,022,709...88,089,426
JBrowse link
G MAGEL2 MAGE family member L2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:142,450,414...142,454,633
Ensembl chr 1:142,448,689...142,454,697
JBrowse link
G TRIM27 tripartite motif containing 27 involved_in IEA Ensembl GO_REF:0000107
G WASHC1 WASH complex subunit 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5603599|PMID:23452853) InterPro
MGI
PMID:23452853 GO_REF:0000002 MGI:5603599 NCBI chr 5:67,395,737...67,412,408
Ensembl chr 5:67,391,277...67,412,434
JBrowse link
G WHAMM WASP homolog associated with actin, golgi membranes and microtubules involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:52,108,867...52,140,333
Ensembl chr 7:52,108,868...52,140,302
JBrowse link
barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,177...1,710,661
JBrowse link
G ADD2 adducin 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:71,729,882...71,845,761
Ensembl chr 3:71,730,002...71,840,862
JBrowse link
G ADD3 adducin 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:120,451,421...120,583,725
Ensembl chr14:120,451,573...120,583,723
JBrowse link
G AVIL advillin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:23,087,946...23,110,602
Ensembl chr 5:23,087,956...23,132,465
JBrowse link
G CAPG capping actin protein, gelsolin like involved_in IEA
IBA
(PMID:21873635) UniProt
GO_Central
PMID:21873635 GO_REF:0000104 NCBI chr 3:59,335,483...59,366,855
Ensembl chr 3:59,335,465...59,366,846
JBrowse link
G CAPZA1 capping actin protein of muscle Z-line subunit alpha 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3758397|PMID:17656356) UniProt
MGI
PMID:17656356 GO_REF:0000104 MGI:3758397 NCBI chr 4:107,769,570...107,821,806
Ensembl chr 4:107,768,080...107,821,819
JBrowse link
G CAPZA2 capping actin protein of muscle Z-line subunit alpha 2 involved_in IBA
IEA
(PMID:21873635) GO_Central
UniProt
PMID:21873635 GO_REF:0000104 NCBI chr18:29,316,384...29,365,062
Ensembl chr18:29,310,756...29,365,144
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(MGI:3758397|PMID:17656356)
GO_Central
MGI
UniProt
PMID:17656356 PMID:21873635 GO_REF:0000104 MGI:3758397 NCBI chr 6:77,780,682...77,912,653
Ensembl chr 6:77,780,681...77,912,617
JBrowse link
G DBNL drebrin like NOT|acts_upstream_of_or_within ISO (MGI:1353214|PMID:10637315) MGI PMID:10637315 MGI:1353214 NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697
JBrowse link
G EPS8 epidermal growth factor receptor pathway substrate 8 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 5:56,817,445...57,005,117
Ensembl chr 5:56,817,606...57,005,114
JBrowse link
G FLII FLII actin remodeling protein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:60,475,722...60,487,376
Ensembl chr12:60,475,733...60,487,415
JBrowse link
G GSN gelsolin involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287
JBrowse link
G GSN gelsolin involved_in IBA (PMID:21873635) GO_Central PMID:21873635
G RDX radixin ISO RGD PMID:2500445 RGD:8693627 NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,441...38,376,439
JBrowse link
G SCIN scinderin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745
JBrowse link
G SVIL supervillin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:41,176,358...41,462,750
Ensembl chr10:41,177,977...41,462,766
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,292...34,371,842
JBrowse link
G VIL1 villin 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
G VILL villin like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:22,831,867...22,851,282
Ensembl chr13:22,831,915...22,851,275
JBrowse link
negative regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADD1 adducin 1 ISO RGD PMID:8675693 RGD:7174724 NCBI chr 8:1,627,146...1,710,653
Ensembl chr 8:1,627,177...1,710,661
JBrowse link
G ARFGEF1 ADP ribosylation factor guanine nucleotide exchange factor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:67,465,517...67,613,611
Ensembl chr 4:67,466,014...67,639,442
JBrowse link
G BBS4 Bardet-Biedl syndrome 4 acts_upstream_of_or_within ISO (MGI:5510934|PMID:23716571) MGI PMID:23716571 MGI:5510934 NCBI chr 7:60,631,913...60,693,359 JBrowse link
G CAPN1 calpain 1 ISO RGD PMID:25653381 RGD:13792590 NCBI chr 2:6,997,513...7,024,410
Ensembl chr 2:6,997,516...7,081,432
JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in ISO (PMID:30250061) UniProt PMID:30250061 NCBI chr 4:10,476,137...10,643,395 JBrowse link
G FHOD3 formin homology 2 domain containing 3 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4422153|PMID:19706596) Ensembl
MGI
PMID:19706596 GO_REF:0000107 MGI:4422153 NCBI chr 6:120,036,824...120,585,987
Ensembl chr 6:120,036,838...120,586,849
JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216
JBrowse link
G KANK1 KN motif and ankyrin repeat domains 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
(PMID:21873635)
(PMID:17996375)
GO_Central
MGI
Ensembl
PMID:17996375 PMID:21873635 GO_REF:0000107 NCBI chr 1:221,015,042...221,218,875
Ensembl chr 1:221,015,046...221,218,575
JBrowse link
G KANK3 KN motif and ankyrin repeat domains 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:70,938,732...70,953,543
Ensembl chr 2:70,938,787...70,953,543
JBrowse link
G KANK4 KN motif and ankyrin repeat domains 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:150,106,628...150,185,667
Ensembl chr 6:150,106,876...150,185,660
JBrowse link
G MKKS MKKS centrosomal shuttling protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5510934|PMID:23716571) Ensembl
MGI
PMID:23716571 GO_REF:0000107 MGI:5510934 NCBI chr17:19,341,024...19,363,007
Ensembl chr17:19,340,977...19,362,871
JBrowse link
G MYADM myeloid associated differentiation marker involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:56,236,306...56,278,577
Ensembl chr 6:56,236,306...56,278,582
JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr12:14,667,643...14,723,296
Ensembl chr12:14,582,481...14,723,336
JBrowse link
G PFN1 profilin 1 involved_in ISO (PMID:7758455) UniProt PMID:7758455 NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660
JBrowse link
G PFN2 profilin 2 involved_in
acts_upstream_of_or_within
ISO (PMID:7758455)
(MGI:4844066|PMID:18001770)
UniProt
MGI
PMID:7758455 PMID:18001770 MGI:4844066 NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742
JBrowse link
G PRKCD protein kinase C delta involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:35,290,835...35,323,245
Ensembl chr13:35,290,264...35,323,356
JBrowse link
G SLIT2 slit guidance ligand 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:14,758,426...15,149,515
Ensembl chr 8:14,756,619...15,149,510
JBrowse link
G SSH1 slingshot protein phosphatase 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr14:41,963,946...42,030,842
Ensembl chr14:41,968,466...42,025,726
JBrowse link
G SSH2 slingshot protein phosphatase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:45,818,103...46,085,720 JBrowse link
G SSH3 slingshot protein phosphatase 3 involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 2:5,185,480...5,193,875
Ensembl chr 2:5,185,489...5,192,846
JBrowse link
G TLR2 toll like receptor 2 involved_in ISO (MGI:5307186|PMID:22198949) ARUK-UCL PMID:22198949 MGI:5307186 NCBI chr 8:75,416,257...75,428,370
Ensembl chr 8:75,411,991...75,446,850
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,292...34,371,842
JBrowse link
negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPIN actin related protein 2/3 complex inhibitor involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 7:55,469,015...55,483,632 JBrowse link
G CORO1A coronin 1A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380
JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORO1B coronin 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,081,294...5,086,698
Ensembl chr 2:5,080,660...5,086,698
JBrowse link
G CTNNA2 catenin alpha 2 involved_in ISO (PMID:30013181) UniProt PMID:30013181 NCBI chr 3:63,205,073...64,417,990 JBrowse link
G DNAI3 dynein axonemal intermediate chain 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:130,765,580...130,826,828
Ensembl chr 4:130,765,354...130,826,630
JBrowse link
G GMFB glia maturation factor beta involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 1:183,846,672...183,863,396
Ensembl chr 1:183,846,672...183,863,392
JBrowse link
G GMFG glia maturation factor gamma involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
(MGI:5505367|PMID:23727094)
(PMID:21873635)
InterPro
MGI
GO_Central
Ensembl
PMID:21873635 PMID:23727094 GO_REF:0000002 GO_REF:0000107 MGI:5505367 NCBI chr 6:47,990,241...47,997,332
Ensembl chr 6:47,990,237...48,000,590
JBrowse link
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:29,996,388...30,024,343
Ensembl chr14:29,993,655...30,024,216
JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in ISO PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,450...9,889,930
JBrowse link
negative regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in IEA InterPro
Ensembl
GO_REF:0000002 GO_REF:0000107 NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,265,130...28,277,649
Ensembl chr 6:28,264,320...28,279,703
JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:55,336,363...55,600,931
Ensembl chr 8:55,463,441...55,600,939
JBrowse link
G LOC100522401 WASH complex subunit 2A involved_in ISO (PMID:20498093) UniProt PMID:20498093 NCBI chr14:90,582,399...90,640,494 JBrowse link
pointed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LMOD1 leiomodin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr10:24,165,293...24,194,823
Ensembl chr10:24,164,792...24,193,820
JBrowse link
G LMOD2 leiomodin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,661...23,812,481
JBrowse link
G NCBP1 nuclear cap binding protein subunit 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:239,492,573...239,543,925
Ensembl chr 1:239,374,934...239,543,585
JBrowse link
G TMOD1 tropomodulin 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:239,375,150...239,468,387
Ensembl chr 1:239,374,934...239,543,585
JBrowse link
G TMOD2 tropomodulin 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:119,956,583...120,009,372
Ensembl chr 1:119,956,588...120,009,364
JBrowse link
G TMOD3 tropomodulin 3 involved_in IEA InterPro GO_REF:0000002 NCBI chr 1:119,864,878...119,948,795
Ensembl chr 1:119,862,244...119,948,883
JBrowse link
G TMOD4 tropomodulin 4 involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:98,074,380...98,079,346
Ensembl chr 4:98,074,496...98,079,343
JBrowse link
positive regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:18256280 RGD:2306202 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,846...20,208,186
JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,401,861...52,414,913
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G ALOX15 arachidonate 15-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:52,287,174...52,295,873
Ensembl chr12:52,286,019...52,414,907
JBrowse link
G ARF6 ADP ribosylation factor 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:179,697,582...179,717,299
Ensembl chr 1:179,697,615...179,717,844
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 acts_upstream_of_or_within ISO (MGI:3818245|PMID:18836449) MGI PMID:18836449 MGI:3818245 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G BAG4 BAG cochaperone 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:48,299,456...48,348,810
Ensembl chr15:48,299,662...48,348,527
JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:1,609,420...1,666,965
Ensembl chr12:1,603,538...1,670,076
JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:5,472,305...5,567,926
Ensembl chr 3:5,472,315...5,567,876
JBrowse link
G BAIAP2L2 BAR/IMD domain containing adaptor protein 2 like 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:9,778,643...9,799,705
Ensembl chr 5:9,778,727...9,799,703
JBrowse link
G BIN1 bridging integrator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:25,328,679...25,379,675
Ensembl chr15:25,328,674...25,383,652
JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 involved_in ISO (MGI:3588909|PMID:16054028) UniProt PMID:16054028 MGI:3588909 NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,739...20,353,431
JBrowse link
G CCL11 chemokine (C-C motif) ligand 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:40,779,906...40,782,862
Ensembl chr12:40,779,173...40,782,893
JBrowse link
G CCL21 C-C motif chemokine ligand 21 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:32,093,783...32,094,482
Ensembl chr10:31,933,733...32,094,583
JBrowse link
G CCL24 C-C motif chemokine ligand 24 involved_in ISO (PMID:19525930) BHF-UCL PMID:19525930 NCBI chr 3:10,347,397...10,361,500 JBrowse link
G CCL26 C-C motif chemokine ligand 26 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:10,381,306...10,385,677
Ensembl chr 3:10,381,296...10,385,796
JBrowse link
G CDC42EP1 CDC42 effector protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:10,244,625...10,253,430
Ensembl chr 5:10,240,697...10,252,988
JBrowse link
G CDC42EP2 CDC42 effector protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:6,897,497...6,904,040
Ensembl chr 2:6,895,817...6,904,040
JBrowse link
G CDC42EP3 CDC42 effector protein 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:102,537,662...102,567,669
Ensembl chr 3:102,538,586...102,567,814
JBrowse link
G CDC42EP4 CDC42 effector protein 4 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:7,637,797...7,660,189
Ensembl chr12:7,638,085...7,660,188
JBrowse link
G CDC42EP5 CDC42 effector protein 5 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:58,852,426...58,857,622
Ensembl chr 6:58,857,090...58,857,551
JBrowse link
G CRACD capping protein inhibiting regulator of actin dynamics involved_in ISO (PMID:30361697) UniProt PMID:30361697 NCBI chr 8:55,336,363...55,600,931
Ensembl chr 8:55,463,441...55,600,939
JBrowse link
G CSF3 colony stimulating factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,445...22,342,163
JBrowse link
G CTTN cortactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,102...3,060,855
JBrowse link
G DLG1 discs large MAGUK scaffold protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3528803|PMID:15699074) Ensembl
MGI
PMID:15699074 GO_REF:0000107 MGI:3528803 NCBI chr13:132,819,931...133,084,880
Ensembl chr13:132,820,870...133,086,843
JBrowse link
G EVL Enah/Vasp-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:120,911,814...121,056,556
Ensembl chr 7:120,911,220...121,056,558
JBrowse link
G FCHSD1 FCH and double SH3 domains 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:143,289,854...143,301,921
Ensembl chr 2:143,289,859...143,304,416
JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in ISO (MGI:6233193|PMID:23437151) UniProt PMID:23437151 MGI:6233193 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926
JBrowse link
G FER FER tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:113,774,120...114,207,307
Ensembl chr 2:113,774,412...114,206,930
JBrowse link
G FMN1 formin 1 acts_upstream_of_or_within ISO (MGI:3027450|PMID:14647292) MGI PMID:14647292 MGI:3027450 NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,008,721
JBrowse link
G GCHFR GTP cyclohydrolase I feedback regulator involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:130,559,223...130,563,598
Ensembl chr 1:130,554,976...130,563,562
JBrowse link
G GRB2 growth factor receptor bound protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3768467|PMID:17923684) Ensembl
MGI
PMID:17923684 GO_REF:0000107 MGI:3768467 NCBI chr12:5,940,723...6,009,095
Ensembl chr12:5,940,647...6,010,835
JBrowse link
G ICAM1 intercellular adhesion molecule 1 ISO RGD PMID:17662049 RGD:7240703 NCBI chr 2:69,097,136...69,107,722
Ensembl chr 2:69,097,122...69,108,205
JBrowse link
G KIRREL1 kirre like nephrin family adhesion molecule 1 acts_upstream_of_or_within ISO (MGI:3768467|PMID:17923684) MGI PMID:17923684 MGI:3768467 NCBI chr 4:92,173,897...92,290,887
Ensembl chr 4:92,176,745...92,290,610
JBrowse link
G LMOD1 leiomodin 1 involved_in ISO (PMID:26370058) UniProt PMID:26370058 NCBI chr10:24,165,293...24,194,823
Ensembl chr10:24,164,792...24,193,820
JBrowse link
G LMOD2 leiomodin 2 involved_in ISO (PMID:26370058) UniProt PMID:26370058 NCBI chr18:23,803,927...23,815,772
Ensembl chr18:23,803,661...23,812,481
JBrowse link
G LOC100522011 apoptosis-associated speck-like protein containing a CARD involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,305,921...17,307,521
Ensembl chr 3:17,306,179...17,307,512
JBrowse link
G MAP3K1 mitogen-activated protein kinase kinase kinase 1 acts_upstream_of_or_within ISO (MGI:2674169|PMID:12941696), (MGI:5608927|PMID:25224220) MGI PMID:12941696 PMID:25224220 MGI:2674169 MGI:5608927 NCBI chr16:35,872,301...35,947,097
Ensembl chr16:35,871,799...35,946,987
JBrowse link
G MLST8 MTOR associated protein, LST8 homolog involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3510095|PMID:15467718) Ensembl
MGI
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr 3:39,778,746...39,786,206
Ensembl chr 3:39,778,754...39,788,309
JBrowse link
G MTOR mechanistic target of rapamycin kinase involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3510095|PMID:15467718) Ensembl
MGI
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888
JBrowse link
G MYO1C myosin IC ISO RGD PMID:22918957 RGD:11073622 NCBI chr12:47,691,252...47,715,670
Ensembl chr12:47,691,252...47,738,439
JBrowse link
G NCK1 NCK adaptor protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3768467|PMID:17923684) UniProt
MGI
PMID:17923684 GO_REF:0000104 MGI:3768467 NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,986,156
JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA UniProt GO_REF:0000104 NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,988...49,198,664
JBrowse link
G NCKAP1 NCK associated protein 1 involved_in ISO (MGI:5897521|PMID:27927633) BHF-UCL PMID:27927633 MGI:5897521 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,141...88,528,231
JBrowse link
G NCKAP1L NCK associated protein 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:19,677,613...19,720,550
Ensembl chr 5:19,677,875...19,723,132
JBrowse link
G NPHS1 NPHS1 adhesion molecule, nephrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:45,248,325...45,271,892
Ensembl chr 6:45,248,317...45,271,550
JBrowse link
G PFN1 profilin 1 involved_in ISO (PMID:23153535) UniProt PMID:23153535 NCBI chr12:51,962,642...51,965,570
Ensembl chr12:51,961,696...51,973,660
JBrowse link
G PFN2 profilin 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3714870|PMID:17541406) MGI
Ensembl
PMID:17541406 GO_REF:0000107 MGI:3714870 NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742
JBrowse link
G PRKCE protein kinase C epsilon involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,909,020
JBrowse link
G PTK2B protein tyrosine kinase 2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,194
JBrowse link
G RAC1 Rac family small GTPase 1 acts_upstream_of_or_within ISO (MGI:2668778|PMID:12853475) MGI PMID:12853475 MGI:2668778 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,771...4,803,687
JBrowse link
G RHOA ras homolog family member A involved_in ISS
ISO
AgBase
RGD
PMID:17369454 GO_REF:0000024 RGD:1642965 NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,836...32,003,722
JBrowse link
G RICTOR RPTOR independent companion of MTOR complex 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3510095|PMID:15467718) Ensembl
MGI
PMID:15467718 GO_REF:0000107 MGI:3510095 NCBI chr16:24,109,934...24,250,019
Ensembl chr16:24,109,934...24,311,231
JBrowse link
G SNX9 sorting nexin 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:9,130,360...9,239,023
Ensembl chr 1:9,130,334...9,239,343
JBrowse link
G TENM1 teneurin transmembrane protein 1 involved_in ISO (MGI:5465054|PMID:22698694) UniProt PMID:22698694 MGI:5465054 NCBI chr  X:101,853,340...102,641,299
Ensembl chr  X:101,856,938...102,411,207
JBrowse link
G VASP vasodilator stimulated phosphoprotein involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:51,872,810...51,886,729
Ensembl chr 6:51,872,812...51,886,830
JBrowse link
positive regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FMN1 formin 1 acts_upstream_of_or_within ISO (MGI:3027450|PMID:14647292) MGI PMID:14647292 MGI:3027450 NCBI chr 1:136,696,353...137,163,532
Ensembl chr 1:136,704,090...137,008,721
JBrowse link
G GSN gelsolin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287
JBrowse link
G MAGEL2 MAGE family member L2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5603599|PMID:23452853) Ensembl
MGI
PMID:23452853 GO_REF:0000107 MGI:5603599 NCBI chr 1:142,450,414...142,454,633
Ensembl chr 1:142,448,689...142,454,697
JBrowse link
G SCIN scinderin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745
JBrowse link
G TRIM27 tripartite motif containing 27 acts_upstream_of_or_within ISO (MGI:5603599|PMID:23452853) MGI PMID:23452853 MGI:5603599
G WHAMM WASP homolog associated with actin, golgi membranes and microtubules involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:52,108,867...52,140,333
Ensembl chr 7:52,108,868...52,140,302
JBrowse link
positive regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr15:106,776,627...106,903,889
Ensembl chr15:106,776,625...106,900,334
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:66,315,438...66,324,641
Ensembl chr13:66,315,433...66,324,174
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 involved_in ISO (PMID:21107423) UniProt PMID:21107423 NCBI chr15:32,064,431...32,175,095 JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926
JBrowse link
G LOC110256054 wiskott-Aldrich syndrome protein family member 1-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:41,049,943...41,076,524 JBrowse link
G NCKAP1 NCK associated protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,141...88,528,231
JBrowse link
G WAS WASP actin nucleation promoting factor involved_in IEA InterPro GO_REF:0000002 NCBI chr  X:42,774,597...42,793,055
Ensembl chr  X:42,774,588...42,793,055
JBrowse link
G WASF1 WASP family member 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:76,107,595...76,180,335 JBrowse link
G WASF2 WASP family member 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:84,621,742...84,697,428
Ensembl chr 6:84,622,775...84,697,429
JBrowse link
G WASF3 WASP family member 3 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:4,261,121...4,366,258
Ensembl chr11:4,261,177...4,366,254
JBrowse link
G WASL WASP like actin nucleation promoting factor involved_in IEA InterPro GO_REF:0000002 NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506
JBrowse link
positive regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:15252126 RGD:2306210 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G CFL1 cofilin 1 ISO RGD PMID:23704350 RGD:11570555 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
regulation of actin filament polymerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABITRAM actin binding transcription modulator involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:249,898,994...249,905,397 JBrowse link
G ARHGAP18 Rho GTPase activating protein 18 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:33,527,734...33,717,980
Ensembl chr 1:33,527,734...33,717,977
JBrowse link
G ARHGAP28 Rho GTPase activating protein 28 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:100,494,385...100,681,008
Ensembl chr 6:100,493,261...100,655,708
JBrowse link
G BAIAP2L1 BAR/IMD domain containing adaptor protein 2 like 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:5,472,305...5,567,926
Ensembl chr 3:5,472,315...5,567,876
JBrowse link
G CORO1A coronin 1A acts_upstream_of_or_within ISO (MGI:3818245|PMID:18836449) MGI PMID:18836449 MGI:3818245 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380
JBrowse link
G CTTN cortactin involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,102...3,060,855
JBrowse link
G CYFIP2 cytoplasmic FMR1 interacting protein 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr16:65,852,584...66,001,576
Ensembl chr16:65,852,588...66,001,559
JBrowse link
G CYRIA CYFIP related Rac1 interactor A involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:120,968,016...121,069,372
Ensembl chr 3:120,968,060...121,069,242
JBrowse link
G CYRIB CYFIP related Rac1 interactor B involved_in IEA InterPro GO_REF:0000002 NCBI chr 4:10,476,137...10,643,395 JBrowse link
G DBN1 drebrin 1 involved_in ISO
IBA
(PMID:21873635) RGD
GO_Central
PMID:19222710 PMID:21873635 RGD:10395284 NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,496,873
JBrowse link
G DBNL drebrin like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697
JBrowse link
G ELN elastin involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3027647|PMID:14614988) Ensembl
MGI
PMID:14614988 GO_REF:0000107 MGI:3027647 NCBI chr 3:11,214,194...11,245,891
Ensembl chr 3:11,214,073...11,244,897
JBrowse link
G ESAM endothelial cell adhesion molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:51,983,019...51,992,415
Ensembl chr 9:51,983,019...51,992,393
JBrowse link
G FCHSD1 FCH and double SH3 domains 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:143,289,854...143,301,921
Ensembl chr 2:143,289,859...143,304,416
JBrowse link
G FCHSD2 FCH and double SH3 domains 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:7,366,516...7,619,960
Ensembl chr 9:7,366,521...7,619,926
JBrowse link
G GBA2 glucosylceramidase beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:236,456,238...236,467,887
Ensembl chr 1:236,455,240...236,468,210
JBrowse link
G HAX1 HCLS1 associated protein X-1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:95,467,629...95,470,972
Ensembl chr 4:95,467,629...95,470,288
JBrowse link
G HCLS1 hematopoietic cell-specific Lyn substrate 1 involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr13:138,852,387...138,883,088
Ensembl chr13:138,855,142...138,906,351
JBrowse link
G LATS1 large tumor suppressor kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:16,274,955...16,320,980
Ensembl chr 1:16,274,970...16,320,619
JBrowse link
G PAK3 p21 (RAC1) activated kinase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:90,941,976...91,244,331
Ensembl chr  X:90,942,232...91,239,440
JBrowse link
G PFN2 profilin 2 involved_in IBA
ISO
IEA
(PMID:21873635) GO_Central
RGD
InterPro
PMID:11027290 PMID:21873635 GO_REF:0000002 RGD:727303 NCBI chr13:90,177,534...90,185,978
Ensembl chr13:90,177,540...90,183,742
JBrowse link
G PIK3R2 phosphoinositide-3-kinase regulatory subunit 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5613738|PMID:25217619) Ensembl
MGI
PMID:25217619 GO_REF:0000107 MGI:5613738 NCBI chr 2:59,637,363...59,652,075 JBrowse link
G PLEKHG2 pleckstrin homology and RhoGEF domain containing G2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:48,069,532...48,080,001
Ensembl chr 6:48,069,564...48,079,672
JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:15473970 RGD:10043779 NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,280...74,940,362
JBrowse link
G PREX1 phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 ISO RGD PMID:18697831 RGD:2314615 NCBI chr17:50,352,273...50,550,402
Ensembl chr17:50,353,145...50,550,404
JBrowse link
G RASA1 RAS p21 protein activator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:94,879,615...94,992,725
Ensembl chr 2:94,878,911...94,993,479
JBrowse link
G WASHC1 WASH complex subunit 1 acts_upstream_of_or_within ISO (MGI:5806548|PMID:26965651) MGI PMID:26965651 MGI:5806548 NCBI chr 5:67,395,737...67,412,408
Ensembl chr 5:67,391,277...67,412,434
JBrowse link
regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VIL1 villin 1 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
G WASHC5 WASH complex subunit 5 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:5883184|PMID:27390154)
GO_Central
MGI
PMID:21873635 PMID:27390154 MGI:5883184 NCBI chr 4:14,598,133...14,667,535
Ensembl chr 4:14,598,148...14,668,327
JBrowse link
regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1AR adaptor related protein complex 1 associated regulatory protein involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:5429457|PMID:22689987) InterPro
MGI
Ensembl
PMID:22689987 GO_REF:0000002 GO_REF:0000107 MGI:5429457 NCBI chr 8:110,386,145...110,420,548
Ensembl chr 8:110,386,776...110,505,320
JBrowse link
G ARF1 ADP ribosylation factor 1 involved_in ISO PMID:23889934 UniProt PMID:23889934 RGD:8553918 NCBI chr 2:51,219,597...51,237,640
Ensembl chr 2:51,219,667...51,237,639
JBrowse link
G ARFIP1 ADP ribosylation factor interacting protein 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:76,168,731...76,270,554
Ensembl chr 8:76,168,388...76,270,787
JBrowse link
G ARFIP2 ADP ribosylation factor interacting protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:3,250,011...3,254,916
Ensembl chr 9:3,249,938...3,285,977
JBrowse link
G FAM241A family with sequence similarity 241 member A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:110,468,450...110,504,828
Ensembl chr 8:110,386,776...110,505,320
JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,450...9,889,930
JBrowse link
regulation of barbed-end actin filament capping term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IQANK1 IQ motif and ankyrin repeat containing 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:852,218...896,425
Ensembl chr 4:852,572...894,779
JBrowse link
G MTPN myotrophin involved_in IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr18:13,330,049...13,395,297
Ensembl chr18:13,330,091...13,400,046
JBrowse link
sequestering of actin monomers term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSN gelsolin involved_in ISO (PMID:19666531) UniProt PMID:19666531 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,295,713...261,385,287
JBrowse link
G LOC110257905 thymosin beta-4-like involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  Y:10,163,547...10,165,732 JBrowse link
G SCIN scinderin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,363,745
JBrowse link
G TMSB15B thymosin beta 15B involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:84,815,565...84,871,809 JBrowse link
G TMSB4X thymosin beta 4 X-linked involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr  X:9,649,516...9,651,662
Ensembl chr  X:9,650,179...9,651,661
JBrowse link
G TWF1 twinfilin actin binding protein 1 involved_in IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 5:74,868,586...74,881,220
Ensembl chr 5:74,868,585...74,893,713
JBrowse link
G TWF2 twinfilin actin binding protein 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,292...34,371,842
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16567
    cellular process 15845
      actin filament-based process 800
        actin cytoskeleton organization 712
          actin filament organization 446
            actin polymerization or depolymerization 218
              actin filament polymerization 189
                actin filament polymerization involved in mitotic actomyosin contractile ring assembly 0
                negative regulation of actin filament polymerization + 66
                positive regulation of actin filament polymerization + 102
                regulation of actin filament polymerization + 172
Path 2
Term Annotations click to browse term
  biological_process 16567
    cellular process 15845
      cellular component organization or biogenesis 6084
        cellular component organization 5916
          organelle organization 3738
            cytoskeleton organization 1378
              actin cytoskeleton organization 712
                actin filament organization 446
                  actin polymerization or depolymerization 218
                    actin filament polymerization 189
                      actin filament polymerization involved in mitotic actomyosin contractile ring assembly 0
                      negative regulation of actin filament polymerization + 66
                      positive regulation of actin filament polymerization + 102
                      regulation of actin filament polymerization + 172
paths to the root