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ONTOLOGY REPORT - ANNOTATIONS

Term:microspike assembly
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Accession:GO:0030035 term browser browse the term
Definition:Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.
Comment:Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. For the assembly of filopodia, use 'filopodium assembly ; GO:0046847'.
Synonyms:exact_synonym: microspike biosynthesis;   microspike formation
 related_synonym: microspike biogenesis
 never_in_taxon: NCBITaxon:4751 ! Fungi


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microspike assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO
IEA		 (PMID:11864995)
GO_REF:0000107		 RGD
Ensembl		 PMID:11864995 GO_REF:0000107 NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Actn2 actinin alpha 2 involved_in ISO
IEA		 (PMID:12356918)
GO_REF:0000107		 RGD
Ensembl		 PMID:12356918 GO_REF:0000107 NCBI chr17:62,835,055...62,902,331
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 acts_upstream_of_or_within ISO
IEA		 (PMID:11527409)
GO_REF:0000107		 RGD
Ensembl		 PMID:11527409 GO_REF:0000107 NCBI chr11:97,904,182...98,055,190
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:20137952), (PMID:9571235)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9571235 PMID:20137952 GO_REF:0000024 GO_REF:0000107 NCBI chr12:16,710,601...16,723,734
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular component organization or biogenesis 7115
        cellular component organization 6828
          cellular component assembly 3218
            cell projection assembly 675
              plasma membrane bounded cell projection assembly 661
                microspike assembly 4
paths to the root