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ONTOLOGY REPORT - ANNOTATIONS


Term:microspike assembly
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Accession:GO:0030035 term browser browse the term
Definition:Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.
Comment:Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. For the assembly of filopodia, use 'filopodium assembly ; GO:0046847'.
Synonyms:exact_synonym: microspike biosynthesis;   microspike formation
 related_synonym: microspike biogenesis



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microspike assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase acts_upstream_of_or_within ISO (MGI:2175933|PMID:11864995) RGD PMID:11864995 MGI:2175933 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Actn2 actinin alpha 2 involved_in ISO (PMID:12356918) RGD PMID:12356918 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:2179874|PMID:11527409)
Ensembl
RGD
PMID:11527409 GO_REF:0000107 MGI:2179874 NCBI chr11:84,399,885...84,551,013
Ensembl chr11:84,399,816...84,546,972
JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:20137952), (PMID:9571235)
UniProt
RGD
PMID:9571235 PMID:20137952 GO_REF:0000024 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          cellular component assembly 3029
            cell projection assembly 623
              plasma membrane bounded cell projection assembly 611
                microspike assembly 4
paths to the root