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ONTOLOGY REPORT - ANNOTATIONS


Term:lamellipodium
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Accession:GO:0030027 term browser browse the term
Definition:A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
Synonyms:xref: Wikipedia:Lamellipodia
 never_in_taxon: NCBITaxon:4751 ! Fungi



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lamellipodium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI1 abl interactor 1 located_in
is_active_in
IEA
IBA
UniProt
GO_Central
Ensembl
GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr10:48,939,407...49,069,269
Ensembl chr10:48,939,446...49,069,441
JBrowse link
G ABI2 abl interactor 2 located_in
is_active_in
IEA
IBA
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000044 NCBI chr15:106,776,627...106,903,889
Ensembl chr15:106,776,631...106,900,333
JBrowse link
G ABI3BP ABI family member 3 binding protein located_in ISO PMID:18480067 ARUK-UCL PMID:18480067 RGD:42721999 NCBI chr13:158,013,704...158,291,093
Ensembl chr13:158,013,726...158,291,103
JBrowse link
G ABITRAM actin binding transcription modulator located_in
is_active_in
IEA
IBA
UniProt
GO_Central
GO_REF:0000033 GO_REF:0000044 NCBI chr 1:249,898,994...249,905,397 JBrowse link
G ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase located_in ISO (PMID:19414610) MGI PMID:19414610 NCBI chr 9:120,888,891...120,984,724
Ensembl chr 9:120,892,952...120,984,695
JBrowse link
G ABLIM1 actin binding LIM protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:124,759,811...125,108,722
Ensembl chr14:124,760,404...125,010,892
JBrowse link
G ABLIM3 actin binding LIM protein family member 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:150,260,185...150,423,214
Ensembl chr 2:150,260,196...150,423,212
JBrowse link
G ACTA1 actin alpha 1, skeletal muscle located_in ISS AgBase GO_REF:0000024 NCBI chr14:60,412,651...60,415,687
Ensembl chr14:60,412,812...60,415,674
JBrowse link
G ACTA2 actin alpha 2, smooth muscle located_in ISS AgBase GO_REF:0000024 NCBI chr14:100,868,145...100,886,732
Ensembl chr14:100,867,733...100,886,713
JBrowse link
G ACTB actin beta located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:4,084,275...4,090,383
Ensembl chr 3:4,082,216...4,090,356
JBrowse link
G ACTC1 actin alpha cardiac muscle 1 located_in ISS AgBase GO_REF:0000024 NCBI chr 1:136,281,119...136,286,551
Ensembl chr 1:136,281,167...136,286,547
JBrowse link
G ACTR2 actin related protein 2 ISO RGD PMID:17442843 RGD:11567221 NCBI chr 3:76,691,275...76,729,269
Ensembl chr 3:76,691,280...76,729,252
JBrowse link
G ACTR3 actin related protein 3 located_in ISO
IEA
RGD
Ensembl
PMID:15252126 GO_REF:0000107 RGD:2306210 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,812...20,167,421
JBrowse link
G AIF1 allograft inflammatory factor 1 located_in ISO
ISS
RGD
UniProt
PMID:16877440 GO_REF:0000024 RGD:2313019 NCBI chr 7:23,711,752...23,731,191
Ensembl chr 7:23,726,787...23,731,671
JBrowse link
G AJUBA ajuba LIM protein located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:76,063,009...76,072,884
Ensembl chr 7:76,063,058...76,076,585
JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:105,328,717...105,401,152
Ensembl chr15:105,328,719...105,401,093
JBrowse link
G AMOT angiomotin located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr  X:92,581,995...92,647,872
Ensembl chr  X:92,582,047...92,647,857
JBrowse link
G AMOTL1 angiomotin like 1 located_in ISO (PMID:19590046) MGI PMID:19590046 NCBI chr 9:26,811,872...26,978,107
Ensembl chr 9:26,864,312...26,973,552
JBrowse link
G APBB1 amyloid beta precursor protein binding family B member 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,303,032...3,323,828
Ensembl chr 9:3,303,112...3,324,037
JBrowse link
G APC APC regulator of WNT signaling pathway located_in ISO
IEA
RGD
Ensembl
PMID:15670646 GO_REF:0000107 RGD:6484522 NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,887
JBrowse link
G ARHGAP31 Rho GTPase activating protein 31 located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr13:140,837,078...140,948,504
Ensembl chr13:140,839,268...140,948,303
JBrowse link
G ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor 6 located_in
is_active_in
IEA
IBA
UniProt
GO_Central
Ensembl
GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr  X:111,796,485...111,917,195
Ensembl chr  X:111,796,485...111,917,174
JBrowse link
G ARHGEF7 Rho guanine nucleotide exchange factor 7 located_in
is_active_in
IEA
IBA
UniProt
GO_Central
Ensembl
GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr11:77,427,352...77,531,001
Ensembl chr11:77,427,368...77,530,993
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 located_in ISO
IEA
RGD
Ensembl
PMID:15684033 GO_REF:0000107 RGD:11575050 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,025...120,328,542
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,814,382...31,823,452
Ensembl chr14:31,814,151...31,826,855
JBrowse link
G ARPC5 actin related protein 2/3 complex subunit 5 located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:124,839,062...124,847,906
Ensembl chr 9:124,837,765...124,848,105
JBrowse link
G ARPIN actin related protein 2/3 complex inhibitor located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:55,469,015...55,483,632
Ensembl chr 7:55,468,568...55,483,536
JBrowse link
G AVIL advillin located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:23,087,946...23,110,602
Ensembl chr 5:23,087,956...23,110,602
JBrowse link
G BAIAP2 BAR/IMD domain containing adaptor protein 2 located_in ISO PMID:18480067 ARUK-UCL PMID:18480067 RGD:42721999 NCBI chr12:1,609,420...1,666,965
Ensembl chr12:1,603,540...1,670,075
JBrowse link
G BCAR1 BCAR1 scaffold protein, Cas family member located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,369,332...12,404,822
Ensembl chr 6:12,367,758...12,404,818
JBrowse link
G BRK1 BRICK1 subunit of SCAR/WAVE actin nucleating complex located_in IEA Ensembl GO_REF:0000107 NCBI chr13:66,315,438...66,324,641
Ensembl chr13:66,315,315...66,324,641
JBrowse link
G CAPZB capping actin protein of muscle Z-line subunit beta located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:77,780,682...77,912,653
Ensembl chr 6:77,780,682...77,912,617
JBrowse link
G CARMIL1 capping protein regulator and myosin 1 linker 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:20,036,430...20,353,431
Ensembl chr 7:20,036,944...20,353,420
JBrowse link
G CARMIL2 capping protein regulator and myosin 1 linker 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:28,265,130...28,277,649
Ensembl chr 6:28,265,135...28,277,641
JBrowse link
G CARMIL3 capping protein regulator and myosin 1 linker 3 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 7:75,222,528...75,241,243
Ensembl chr 7:75,222,528...75,241,242
JBrowse link
G CASP8 caspase 8 located_in IEA Ensembl GO_REF:0000107 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468
JBrowse link
G CCDC88A coiled-coil domain containing 88A located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:85,811,043...85,971,162
Ensembl chr 3:85,811,127...85,941,864
JBrowse link
G CDC42BPA CDC42 binding protein kinase alpha located_in IEA UniProt GO_REF:0000044 NCBI chr10:14,649,278...14,940,988
Ensembl chr10:14,652,855...14,940,825
JBrowse link
G CDC42BPB CDC42 binding protein kinase beta located_in IEA UniProt GO_REF:0000044
G CDH1 cadherin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:18,075,487...18,155,986
Ensembl chr 6:18,075,480...18,155,986
JBrowse link
G CDH2 cadherin 2 located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 6:112,396,713...112,629,073
Ensembl chr 6:112,396,721...112,628,432
JBrowse link
G CDK5 cyclin dependent kinase 5 located_in ISO (PMID:12496365) MGI PMID:12496365 NCBI chr18:6,166,914...6,171,157 JBrowse link
G CFL1 cofilin 1 is_active_in
located_in
ISO
IBA
IEA
ISS
RGD
GO_Central
UniProt
PMID:15252126 GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 RGD:2306210 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G CIB1 calcium and integrin binding 1 located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 7:55,794,834...55,798,666
Ensembl chr 7:55,794,836...55,798,590
JBrowse link
G CLRN1 clarin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:91,104,850...91,152,397
Ensembl chr13:91,106,207...91,148,031
JBrowse link
G CORO1A coronin 1A located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,898...18,342,396
JBrowse link
G CORO1B coronin 1B located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:5,081,294...5,086,698
Ensembl chr 2:5,080,660...5,086,690
JBrowse link
G CORO1C coronin 1C located_in IEA Ensembl GO_REF:0000107 NCBI chr14:42,062,468...42,145,130
Ensembl chr14:42,062,893...42,145,123
JBrowse link
G CTNNA1 catenin alpha 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:140,682,776...140,869,828
Ensembl chr 2:140,682,371...140,871,334
JBrowse link
G CTNNA2 catenin alpha 2 located_in ISO (PMID:14657280) MGI PMID:14657280 NCBI chr 3:63,205,073...64,417,990
Ensembl chr 3:63,205,084...63,455,471
JBrowse link
G CTNNA3 catenin alpha 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:69,195,231...70,974,543
Ensembl chr14:69,195,961...70,938,204
JBrowse link
G CTNNB1 catenin beta 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311
JBrowse link
G CTNND1 catenin delta 1 located_in ISO (PMID:14657280) RGD
MGI
PMID:12727444 PMID:14657280 RGD:2316208 NCBI chr 2:13,143,604...13,209,251
Ensembl chr 2:13,154,338...13,209,250
JBrowse link
G CTTN cortactin located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 2:3,031,103...3,060,796
Ensembl chr 2:3,031,103...3,060,813
JBrowse link
G CYFIP1 cytoplasmic FMR1 interacting protein 1 located_in ISO (PMID:14765121) MGI PMID:14765121 NCBI chr15:32,064,431...32,175,095
Ensembl chr15:32,064,475...32,175,094
JBrowse link
G DAG1 dystroglycan 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:32,028,019...32,092,450
Ensembl chr13:32,029,522...32,092,450
JBrowse link
G DBN1 drebrin 1 is_active_in ISO
IBA
RGD
GO_Central
PMID:19222710 GO_REF:0000033 RGD:10395284 NCBI chr 2:80,480,603...80,495,797
Ensembl chr 2:80,479,460...80,495,796
JBrowse link
G DBNL drebrin like located_in
is_active_in
IEA
IBA
UniProt
GO_Central
Ensembl
GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr18:48,713,335...48,725,692
Ensembl chr18:48,713,340...48,725,697
JBrowse link
G DGKZ diacylglycerol kinase zeta located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:16,134,046...16,176,043
Ensembl chr 2:16,134,048...16,176,238
JBrowse link
G DMD dystrophin ISO RGD PMID:11368101 RGD:12880029 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,231...28,383,840
JBrowse link
G DNM2 dynamin 2 ISO RGD PMID:9725914 RGD:9685132 NCBI chr 2:69,474,011...69,574,427
Ensembl chr 2:69,474,031...69,574,424
JBrowse link
G DPP4 dipeptidyl peptidase 4 located_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr15:68,661,764...68,742,961
Ensembl chr15:68,660,521...68,743,663
JBrowse link
G DPYSL3 dihydropyrimidinase like 3 located_in ISO PMID:16181627 UniProt PMID:16181627 RGD:8553533 NCBI chr 2:148,663,563...148,777,055
Ensembl chr 2:148,662,051...148,776,619
JBrowse link
G DYNLT1 dynein light chain Tctex-type 1 ISO RGD PMID:15992542 RGD:8553295 NCBI chr 1:8,556,083...8,562,865
Ensembl chr 1:8,556,059...8,563,676
JBrowse link
G DYSF dysferlin located_in ISO (PMID:18325335) UniProt PMID:18325335 NCBI chr 3:71,020,143...71,237,658
Ensembl chr 3:71,020,144...71,246,967
JBrowse link
G ENAH ENAH actin regulator located_in IEA UniProt GO_REF:0000044 NCBI chr10:13,439,772...13,609,347
Ensembl chr10:13,446,426...13,609,303
JBrowse link
G EPHA2 EPH receptor A2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:75,251,465...75,279,364
Ensembl chr 6:75,251,467...75,279,314
JBrowse link
G EVL Enah/Vasp-like located_in IEA UniProt GO_REF:0000044 NCBI chr 7:120,911,814...121,056,556
Ensembl chr 7:120,911,648...121,056,555
JBrowse link
G FAM89B family with sequence similarity 89 member B located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:6,680,832...6,682,506
Ensembl chr 2:6,681,490...6,682,511
JBrowse link
G FAP fibroblast activation protein alpha located_in IEA Ensembl GO_REF:0000107 NCBI chr15:68,831,281...68,902,416
Ensembl chr15:68,830,730...68,902,379
JBrowse link
G FAT1 FAT atypical cadherin 1 located_in ISO (PMID:15148305) MGI PMID:15148305 NCBI chr17:8,466,099...8,580,715
Ensembl chr17:8,457,187...8,580,715
JBrowse link
G FER FER tyrosine kinase located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:113,774,120...114,207,307
Ensembl chr 2:113,774,412...114,206,930
JBrowse link
G FGD1 FYVE, RhoGEF and PH domain containing 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:47,191,838...47,231,656
Ensembl chr  X:47,192,427...47,231,342
JBrowse link
G FGD4 FYVE, RhoGEF and PH domain containing 4 located_in ISO (PMID:11527409) MGI PMID:11527409 NCBI chr 5:41,683,265...41,879,197
Ensembl chr 5:41,680,452...41,879,062
JBrowse link
G FLOT1 flotillin 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,253,157...23,265,165
Ensembl chr 7:23,253,162...23,265,106
JBrowse link
G FLOT2 flotillin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:45,102,205...45,120,503
Ensembl chr12:45,101,531...45,120,455
JBrowse link
G FSCN1 fascin actin-bundling protein 1 located_in ISO
IEA
RGD
Ensembl
PMID:18855019 GO_REF:0000107 RGD:2317768 NCBI chr 3:4,134,173...4,143,275
Ensembl chr 3:4,134,177...4,143,286
JBrowse link
G FSCN3 fascin actin-bundling protein 3 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr18:20,684,621...20,693,552
Ensembl chr18:20,686,746...20,693,552
JBrowse link
G GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:56,449,430...56,460,399
Ensembl chr  X:56,449,425...56,460,392
JBrowse link
G GSN gelsolin located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:261,295,711...261,372,848
Ensembl chr 1:261,307,008...261,372,848
JBrowse link
G HAX1 HCLS1 associated protein X-1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:95,467,629...95,470,972
Ensembl chr 4:95,467,632...95,470,290
JBrowse link
G IGF2BP1 insulin like growth factor 2 mRNA binding protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr12:25,196,955...25,244,660
Ensembl chr12:25,197,058...25,243,272
JBrowse link
G ILK integrin linked kinase located_in IEA Ensembl GO_REF:0000107 NCBI chr 9:3,145,647...3,152,097
Ensembl chr 9:3,145,608...3,159,858
JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 located_in ISO
IEA
RGD
UniProt
PMID:17535963 GO_REF:0000044 RGD:2312439 NCBI chr 9:6,793,971...6,807,286
Ensembl chr 9:6,793,069...6,808,028
JBrowse link
G IQGAP2 IQ motif containing GTPase activating protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,294,423...85,633,645
Ensembl chr 2:85,294,530...85,633,642
JBrowse link
G ITGB1 integrin subunit beta 1 located_in IEA UniProt GO_REF:0000044 NCBI chr10:56,078,393...56,130,608
Ensembl chr10:56,078,396...56,173,326
JBrowse link
G ITGB1BP1 integrin subunit beta 1 binding protein 1 located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 3:126,905,779...126,921,961
Ensembl chr 3:126,905,810...126,922,045
JBrowse link
G ITSN1 intersectin 1 located_in ISO (PMID:11744688) MGI PMID:11744688 NCBI chr13:197,301,515...197,492,537
Ensembl chr13:197,249,061...197,481,245
JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 located_in ISO PMID:12151401 UniProt PMID:12151401 RGD:10047206 NCBI chr 4:109,534,923...109,570,172
Ensembl chr 4:109,557,973...109,560,998
JBrowse link
G KITLG KIT ligand located_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000044 GO_REF:0000107 NCBI chr 5:94,016,992...94,110,219
Ensembl chr 5:94,017,387...94,110,214
JBrowse link
G KPTN kaptin, actin binding protein located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 6:53,238,650...53,246,458
Ensembl chr 6:53,238,666...53,249,163
JBrowse link
G LIMK1 LIM domain kinase 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:11,252,820...11,279,286
Ensembl chr 3:11,252,648...11,279,284
JBrowse link
G LOC100621521 ABI gene family member 3 is_active_in
located_in
IBA
ISO
(PMID:18480067)
(PMID:17101133)
GO_Central
ARUK-UCL
MGI
PMID:17101133 PMID:18480067 GO_REF:0000033 NCBI chr12:25,426,116...25,441,309 JBrowse link
G LOC110255205 ABI gene family member 3-like is_active_in IBA GO_Central GO_REF:0000033 NCBI chr12:25,322,040...25,336,099 JBrowse link
G LOC110256054 wiskott-Aldrich syndrome protein family member 1-like is_active_in IBA GO_Central GO_REF:0000033 NCBI chr12:41,049,943...41,076,524 JBrowse link
G MCF2L MCF.2 cell line derived transforming sequence like located_in ISO (PMID:12637522) MGI PMID:12637522 NCBI chr11:78,407,525...78,505,495
Ensembl chr11:78,408,056...78,505,493
JBrowse link
G MED18 mediator complex subunit 18 located_in IEA UniProt GO_REF:0000044 GO_REF:0000104 NCBI chr 6:85,384,085...85,392,296
Ensembl chr 6:85,384,080...85,392,291
JBrowse link
G MTSS2 MTSS I-BAR domain containing 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:13,660,388...13,682,311
Ensembl chr 6:13,660,392...13,682,316
JBrowse link
G MYH10 myosin heavy chain 10 ISO RGD PMID:25131674 RGD:12798516 NCBI chr12:53,647,579...53,781,552 JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:25131674 RGD:12798516 NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472
JBrowse link
G MYLK myosin light chain kinase located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr13:136,509,878...136,809,674
Ensembl chr13:136,509,755...136,809,668
JBrowse link
G MYO1G myosin IG located_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,466,450...50,483,520
Ensembl chr18:50,466,449...50,483,518
JBrowse link
G MYO9B myosin IXB located_in
is_active_in
ISO
IBA
(PMID:17314409) RGD
MGI
GO_Central
PMID:9348541 PMID:17314409 GO_REF:0000033 RGD:1581711 NCBI chr 2:60,455,605...60,567,479
Ensembl chr 2:60,455,607...60,567,467
JBrowse link
G NCKAP1 NCK associated protein 1 located_in ISO (PMID:14765121), (PMID:27927633) BHF-UCL PMID:14765121 PMID:27927633 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,142...88,528,326
JBrowse link
G NF2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor located_in IEA Ensembl GO_REF:0000107 NCBI chr14:46,653,869...46,726,421
Ensembl chr14:46,653,900...46,731,999
JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 located_in ISS
IEA
UniProt GO_REF:0000024 GO_REF:0000044 NCBI chr12:27,439,529...27,445,025
Ensembl chr12:27,439,260...27,445,027
JBrowse link
G P4HB prolyl 4-hydroxylase subunit beta located_in IEA Ensembl GO_REF:0000107 NCBI chr12:1,121,816...1,131,291
Ensembl chr12:1,121,824...1,131,289
JBrowse link
G PAK1 p21 (RAC1) activated kinase 1 ISO RGD PMID:19574218 RGD:11533928 NCBI chr 9:11,830,095...11,973,074
Ensembl chr 9:11,830,095...12,020,415
JBrowse link
G PALLD palladin, cytoskeletal associated protein located_in IEA Ensembl GO_REF:0000107 NCBI chr14:20,678,456...21,020,125
Ensembl chr14:20,678,452...21,020,125
JBrowse link
G PARVA parvin alpha located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:46,839,081...47,028,102
Ensembl chr 2:46,839,485...47,028,963
JBrowse link
G PARVB parvin beta located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 5:4,906,667...5,015,494
Ensembl chr 5:4,906,685...5,015,441
JBrowse link
G PDLIM4 PDZ and LIM domain 4 located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 2:134,555,367...134,570,356
Ensembl chr 2:134,555,666...134,570,348
JBrowse link
G PDPN podoplanin is_active_in
located_in
IBA
ISO
(PMID:10574709) GO_Central
UniProt
PMID:10574709 GO_REF:0000033 NCBI chr 6:73,019,063...73,050,000
Ensembl chr 6:73,019,057...73,049,996
JBrowse link
G PDXP pyridoxal phosphatase located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:10,162,642...10,169,726
Ensembl chr 5:10,162,643...10,169,512
JBrowse link
G PEAR1 platelet endothelial aggregation receptor 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:93,178,854...93,205,186
Ensembl chr 4:93,177,158...93,205,155
JBrowse link
G PHACTR4 phosphatase and actin regulator 4 located_in IEA UniProt
Ensembl
GO_REF:0000044 GO_REF:0000104 GO_REF:0000107 NCBI chr 6:85,411,993...85,529,441
Ensembl chr 6:85,412,134...85,528,715
JBrowse link
G PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha located_in IEA Ensembl GO_REF:0000107 NCBI chr13:117,193,935...117,282,151
Ensembl chr13:117,180,544...117,274,587
JBrowse link
G PIP5K1A phosphatidylinositol-4-phosphate 5-kinase type 1 alpha located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:98,012,941...98,062,166
Ensembl chr 4:98,012,945...98,056,815
JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:131,002,973...131,058,932
Ensembl chr 8:131,005,407...131,058,932
JBrowse link
G PKN2 protein kinase N2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:127,579,097...127,709,982
Ensembl chr 4:127,573,703...127,709,942
JBrowse link
G PLCE1 phospholipase C epsilon 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:105,422,628...105,764,736
Ensembl chr14:105,458,916...105,764,737
JBrowse link
G PLCG1 phospholipase C gamma 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:43,810,003...43,844,553
Ensembl chr17:43,810,048...43,844,554
JBrowse link
G PLD1 phospholipase D1 ISO RGD PMID:18344600 RGD:2299899 NCBI chr13:110,152,268...110,376,319
Ensembl chr13:110,154,874...110,376,294
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:18344600 RGD:2299899 NCBI chr12:52,073,913...52,087,804
Ensembl chr12:52,073,914...52,087,809
JBrowse link
G PLEKHG5 pleckstrin homology and RhoGEF domain containing G5 located_in ISO (PMID:21543326) UniProt PMID:21543326 NCBI chr 6:67,316,818...67,373,787
Ensembl chr 6:67,321,534...67,362,838
JBrowse link
G PLEKHH2 pleckstrin homology, MyTH4 and FERM domain containing H2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:96,707,397...96,833,431
Ensembl chr 3:96,709,059...96,833,410
JBrowse link
G PLXND1 plexin D1 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:68,946,658...68,996,625
Ensembl chr13:68,946,665...68,996,618
JBrowse link
G PODXL podocalyxin like located_in IEA UniProt GO_REF:0000044 NCBI chr18:17,444,339...17,494,507 JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:9362513 RGD:625592 NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,403...74,940,362
JBrowse link
G PPP1R9B protein phosphatase 1 regulatory subunit 9B located_in IEA Ensembl GO_REF:0000107 NCBI chr12:26,319,123...26,337,089
Ensembl chr12:26,319,124...26,336,562
JBrowse link
G PTK2 protein tyrosine kinase 2 located_in ISO (PMID:15728191) MGI PMID:15728191 NCBI chr 4:2,656,606...2,896,060
Ensembl chr 4:2,656,614...2,896,054
JBrowse link
G PTK2B protein tyrosine kinase 2 beta located_in IEA Ensembl GO_REF:0000107 NCBI chr14:11,063,662...11,194,196
Ensembl chr14:11,064,492...11,194,192
JBrowse link
G PTPN13 protein tyrosine phosphatase non-receptor type 13 located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:132,035,170...132,200,425
Ensembl chr 8:132,035,151...132,249,411
JBrowse link
G PTPRM protein tyrosine phosphatase receptor type M located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:99,350,301...100,092,966
Ensembl chr 6:99,350,303...100,092,883
JBrowse link
G PTPRZ1 protein tyrosine phosphatase receptor type Z1 ISO RGD PMID:9660874 RGD:9589123 NCBI chr18:25,046,027...25,228,276
Ensembl chr18:25,045,742...25,168,053
JBrowse link
G PXN paxillin located_in ISO (PMID:12686598)
(PMID:14636584)
BHF-UCL
MGI
PMID:12686598 PMID:14636584 NCBI chr14:40,227,894...40,278,785
Ensembl chr14:40,227,895...40,278,734
JBrowse link
G RAB13 RAB13, member RAS oncogene family located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 4:95,705,093...95,709,942
Ensembl chr 4:95,705,220...95,711,729
JBrowse link
G RAC1 Rac family small GTPase 1 located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,780...4,803,543
JBrowse link
G RAC2 Rac family small GTPase 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:10,553,986...10,571,082
Ensembl chr 5:10,553,433...10,573,014
JBrowse link
G RAPGEF3 Rap guanine nucleotide exchange factor 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:78,101,286...78,134,150
Ensembl chr 5:78,101,299...78,134,105
JBrowse link
G RDX radixin located_in ISO PMID:21047789
(PMID:21047789), (PMID:9563848)
UniProt
MGI
PMID:9563848 PMID:21047789 RGD:10054076 NCBI chr 9:38,243,608...38,299,561
Ensembl chr 9:38,220,447...38,322,097
JBrowse link
G RHOA ras homolog family member A located_in IEA
ISS
Ensembl
AgBase
GO_REF:0000024 GO_REF:0000107 NCBI chr13:31,918,484...31,991,207
Ensembl chr13:31,918,834...31,986,607
JBrowse link
G RNH1 ribonuclease/angiogenin inhibitor 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 2:281,919...290,522
Ensembl chr 2:281,928...290,079
JBrowse link
G ROCK1 Rho associated coiled-coil containing protein kinase 1 located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 6:106,163,899...106,314,998
Ensembl chr 6:106,163,989...106,314,944
JBrowse link
G RSL1D1 ribosomal L1 domain containing 1 is_active_in IBA GO_Central GO_REF:0000033 NCBI chr 3:31,278,394...31,291,205
Ensembl chr 3:31,278,852...31,293,246
JBrowse link
G RUFY3 RUN and FYVE domain containing 3 located_in ISO PMID:17439943 UniProt PMID:17439943 RGD:8554472 NCBI chr 8:67,494,552...67,582,144
Ensembl chr 8:67,495,033...67,582,142
JBrowse link
G SCYL3 SCY1 like pseudokinase 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 4:81,134,035...81,175,537
Ensembl chr 4:81,134,352...81,175,536
JBrowse link
G SH3BP1 SH3 domain binding protein 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 5:10,172,303...10,187,883
Ensembl chr 5:10,172,667...10,187,906
JBrowse link
G SH3RF1 SH3 domain containing ring finger 1 located_in IEA UniProt GO_REF:0000044 NCBI chr14:20,420,618...20,559,273
Ensembl chr14:20,420,618...20,559,271
JBrowse link
G SHTN1 shootin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr14:127,065,507...127,175,222
Ensembl chr14:127,064,397...127,175,227
JBrowse link
G SNAP25 synaptosome associated protein 25 ISO RGD PMID:10625663 RGD:1299445 NCBI chr17:19,096,115...19,227,580
Ensembl chr17:19,141,464...19,227,576
JBrowse link
G SNX1 sorting nexin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 1:107,903,954...107,949,920
Ensembl chr 1:107,903,741...107,949,923
JBrowse link
G SNX2 sorting nexin 2 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:126,271,213...126,329,831
Ensembl chr 2:126,271,267...126,334,119
JBrowse link
G SORBS2 sorbin and SH3 domain containing 2 located_in IEA UniProt GO_REF:0000044 NCBI chr15:46,585,599...46,910,679
Ensembl chr15:46,585,602...46,795,038
JBrowse link
G SPATA13 spermatogenesis associated 13 located_in ISO (PMID:17599059), (PMID:19151759) UniProt PMID:17599059 PMID:19151759 NCBI chr11:2,806,674...3,161,372 JBrowse link
G SPEF1 sperm flagellar 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr17:31,934,856...31,938,463
Ensembl chr17:31,934,856...31,938,463
JBrowse link
G SRCIN1 SRC kinase signaling inhibitor 1 ISO RGD PMID:10625663 RGD:1299445 NCBI chr12:23,494,487...23,571,560
Ensembl chr12:23,495,669...23,570,762
JBrowse link
G SRGAP2 SLIT-ROBO Rho GTPase activating protein 2 located_in ISO (PMID:20810653) UniProt PMID:20810653 NCBI chr 9:66,838,062...67,117,315
Ensembl chr 9:66,838,123...67,117,315
JBrowse link
G STMN2 stathmin 2 located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 4:56,952,968...57,006,744
Ensembl chr 4:56,952,978...57,006,462
JBrowse link
G STX2 syntaxin 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr14:24,341,473...24,380,536
Ensembl chr14:24,341,549...24,380,626
JBrowse link
G STX3 syntaxin 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:11,694,788...11,739,858
Ensembl chr 2:11,696,913...11,740,744
JBrowse link
G STX4 syntaxin 4 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,422,266...17,431,377
Ensembl chr 3:17,416,842...17,431,053
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chr 2:71,504,575...71,513,446
Ensembl chr 2:71,504,569...71,513,422
JBrowse link
G TESC tescalcin located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr14:35,381,899...35,452,215
Ensembl chr14:35,381,923...35,439,253
JBrowse link
G TRPV2 transient receptor potential cation channel subfamily V member 2 ISO RGD PMID:25869297 RGD:9999444 NCBI chr12:59,132,529...59,152,633
Ensembl chr12:59,135,329...59,152,228
JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 located_in ISO PMID:20657843 BHF-UCL PMID:20657843 RGD:8553293 NCBI chr14:41,125,819...41,169,582
Ensembl chr14:41,125,869...41,169,578
JBrowse link
G TSC1 TSC complex subunit 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:272,636,530...272,685,948
Ensembl chr 1:272,636,532...272,685,951
JBrowse link
G TUBB3 tubulin beta 3 class III located_in IEA Ensembl GO_REF:0000107 Ensembl chr 6:169,069...178,410 JBrowse link
G TWF2 twinfilin actin binding protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr13:34,361,294...34,370,997
Ensembl chr13:34,361,297...34,371,277
JBrowse link
G UNC5C unc-5 netrin receptor C located_in IEA Ensembl GO_REF:0000107 NCBI chr 8:124,149,364...124,533,755
Ensembl chr 8:124,142,030...124,530,603
JBrowse link
G VAMP7 vesicle associated membrane protein 7 located_in IEA Ensembl GO_REF:0000107 NCBI chr  X:125,863,266...125,917,232
Ensembl chr  X:125,863,292...125,917,225
JBrowse link
G VASP vasodilator stimulated phosphoprotein located_in IEA Ensembl
UniProt
GO_REF:0000044 GO_REF:0000107 NCBI chr 6:51,872,810...51,886,729
Ensembl chr 6:51,872,812...51,886,724
JBrowse link
G VIL1 villin 1 located_in
is_active_in
ISS
IBA
IEA
UniProt
GO_Central
Ensembl
GO_REF:0000024 GO_REF:0000033 GO_REF:0000044 GO_REF:0000107 NCBI chr15:120,463,470...120,494,772
Ensembl chr15:120,463,566...120,492,580
JBrowse link
G WASF1 WASP family member 1 located_in ISO (PMID:15148305) MGI PMID:15148305 NCBI chr 1:76,107,595...76,180,335 JBrowse link
G WASF2 WASP family member 2 located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr 6:84,621,742...84,697,428
Ensembl chr 6:84,622,800...84,697,429
JBrowse link
G WASF3 WASP family member 3 located_in
is_active_in
IEA
IBA
Ensembl
GO_Central
GO_REF:0000033 GO_REF:0000107 NCBI chr11:4,261,121...4,366,258
Ensembl chr11:4,261,177...4,366,253
JBrowse link
G WASHC1 WASH complex subunit 1 located_in ISO (PMID:18159949) UniProt PMID:18159949 NCBI chr 5:67,395,737...67,412,408
Ensembl chr 5:67,394,875...67,412,431
JBrowse link
G WASL WASP like actin nucleation promoting factor located_in IEA Ensembl GO_REF:0000107 NCBI chr18:23,722,188...23,789,516
Ensembl chr18:23,722,188...23,789,506
JBrowse link
growth cone lamellipodium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APBB1 amyloid beta precursor protein binding family B member 1 ISO RGD PMID:12843239 RGD:10053998 NCBI chr 9:3,303,032...3,323,828
Ensembl chr 9:3,303,112...3,324,037
JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:12843239 RGD:10053998 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056
JBrowse link
G PPP1R9A protein phosphatase 1 regulatory subunit 9A ISO RGD PMID:9362513 RGD:625592 NCBI chr 9:74,635,285...74,944,050
Ensembl chr 9:74,635,403...74,940,362
JBrowse link
lamellipodium membrane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANTXR1 ANTXR cell adhesion molecule 1 located_in IEA Ensembl GO_REF:0000107 NCBI chr 3:73,157,744...73,398,379
Ensembl chr 3:73,157,747...73,398,379
JBrowse link
G APC2 APC regulator of WNT signaling pathway 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:77,005,706...77,034,583
Ensembl chr 2:77,005,706...77,034,561
JBrowse link
G CD44 CD44 molecule located_in IEA Ensembl GO_REF:0000107 NCBI chr 2:25,788,699...25,884,209
Ensembl chr 2:25,788,703...25,884,153
JBrowse link
G CDC42 cell division cycle 42 located_in IEA UniProt GO_REF:0000044 NCBI chr 6:80,035,034...80,089,243
Ensembl chr 6:80,035,123...80,089,233
JBrowse link
G CFL1 cofilin 1 located_in IEA UniProt GO_REF:0000044 NCBI chr 2:6,471,558...6,475,019
Ensembl chr 2:6,469,254...6,475,035
JBrowse link
G DPP4 dipeptidyl peptidase 4 located_in IEA UniProt GO_REF:0000044 NCBI chr15:68,661,764...68,742,961
Ensembl chr15:68,660,521...68,743,663
JBrowse link
G FAP fibroblast activation protein alpha located_in IEA UniProt GO_REF:0000044 NCBI chr15:68,831,281...68,902,416
Ensembl chr15:68,830,730...68,902,379
JBrowse link
G ITGAV integrin subunit alpha V located_in IEA Ensembl GO_REF:0000107 NCBI chr15:91,604,666...91,711,843
Ensembl chr15:91,604,676...91,711,851
JBrowse link
G ITGB3 integrin subunit beta 3 located_in IEA Ensembl GO_REF:0000107 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,514...16,752,292
JBrowse link
G KCNA2 potassium voltage-gated channel subfamily A member 2 located_in IEA UniProt GO_REF:0000044 NCBI chr 4:109,534,923...109,570,172
Ensembl chr 4:109,557,973...109,560,998
JBrowse link
G NCKAP1 NCK associated protein 1 located_in IEA UniProt GO_REF:0000044 NCBI chr15:88,425,861...88,528,417
Ensembl chr15:88,425,142...88,528,326
JBrowse link
G PDPN podoplanin located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:73,019,063...73,050,000
Ensembl chr 6:73,019,057...73,049,996
JBrowse link
G SLC39A6 solute carrier family 39 member 6 located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:119,861,853...119,885,836
Ensembl chr 6:119,861,846...119,885,378
JBrowse link
G SYNE2 spectrin repeat containing nuclear envelope protein 2 located_in IEA Ensembl GO_REF:0000107 NCBI chr 1:193,909,563...194,352,550
Ensembl chr 1:193,911,965...194,264,354
JBrowse link
leading edge of lamellipodium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTR3 actin related protein 3 ISO RGD PMID:17855387 RGD:2306203 NCBI chr15:20,104,808...20,171,721
Ensembl chr15:20,104,812...20,167,421
JBrowse link
G DUSP22 dual specificity phosphatase 22 located_in IEA Ensembl GO_REF:0000107 NCBI chr 7:43,437...96,270
Ensembl chr 7:43,487...96,267
JBrowse link
G PDPN podoplanin located_in IEA Ensembl GO_REF:0000107 NCBI chr 6:73,019,063...73,050,000
Ensembl chr 6:73,019,057...73,049,996
JBrowse link
G PHPT1 phosphohistidine phosphatase 1 located_in ISO (PMID:27924678) ARUK-UCL PMID:27924678

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 18473
    cellular anatomical structure 18252
      cell leading edge 431
        lamellipodium 189
          growth cone lamellipodium 3
          lamellipodium membrane 14
          leading edge of lamellipodium 4
Path 2
Term Annotations click to browse term
  cellular_component 18473
    cellular anatomical structure 18252
      cell projection 2469
        plasma membrane bounded cell projection 2402
          lamellipodium 189
            growth cone lamellipodium 3
            lamellipodium membrane 14
            leading edge of lamellipodium 4
paths to the root