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ONTOLOGY REPORT - ANNOTATIONS

Term:CCR4-NOT complex
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Accession:GO:0030014 term browser browse the term
Definition:The Ccr4-Not complex is an eukaryotically conserved deadenylase that can initiate cytoplasmic mRNA decay, and reduce translation by releasing poly(A)-binding protein (Pab1/PABPC1). Ccr4-Not contains seven core subunits, including two poly(A)-specific exonucleases, Ccr4/CNOT6/CNOT6L and Caf1/Pop2/CNOT7/CNOT8.


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CCR4-NOT complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot1 CCR4-NOT transcription complex, subunit 1 part_of ISO (PMID:19558367) RGD PMID:19558367 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574 		JBrowse link
G Cnot10 CCR4-NOT transcription complex, subunit 10 part_of ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000104
(PMID:19558367), (PMID:23232451)		 UniProt
GO_Central
RGD		 PMID:19558367 PMID:23232451 GO_REF:0000024 GO_REF:0000033 GO_REF:0000104 NCBI chr 8:114,280,486...114,330,110
Ensembl chr 8:114,280,490...114,330,107 		JBrowse link
G Cnot11 CCR4-NOT transcription complex, subunit 11 part_of ISO
IBA
ISS		 (PMID:19558367), (PMID:23232451), (PMID:23303381)
GO_REF:0000033
GO_REF:0000024		 RGD
GO_Central
UniProt		 PMID:19558367 PMID:23232451 PMID:23303381 GO_REF:0000024 GO_REF:0000033 NCBI chr 9:41,814,923...41,824,626
Ensembl chr 9:41,814,907...41,824,620 		JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 part_of ISO (PMID:19558367) RGD PMID:19558367 NCBI chr 7:52,130,445...52,222,338
Ensembl chr 7:52,130,441...52,223,575 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 part_of ISO (PMID:19558367) RGD PMID:19558367 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167 		JBrowse link
G Cnot4 CCR4-NOT transcription complex, subunit 4 located_in
part_of		 ISO
IBA		 (PMID:19558367)
GO_REF:0000033		 RGD
GO_Central		 PMID:19558367 GO_REF:0000033 NCBI chr 4:63,712,770...63,814,355
Ensembl chr 4:63,712,770...63,814,360 		JBrowse link
G Cnot6 CCR4-NOT transcription complex, subunit 6 part_of ISO
IBA
IEA
ISS		 (PMID:19558367)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
TreeGrafter
Ensembl
UniProt		 PMID:19558367 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:33,978,785...34,031,025
Ensembl chr10:33,980,831...34,031,025 		JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like part_of ISO
IBA		 (PMID:19558367)
GO_REF:0000033		 RGD
GO_Central		 PMID:19558367 GO_REF:0000033 NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 part_of ISO (PMID:19558367), (PMID:21336257)
UniProtKB:P31384 (PMID:7791755)		 RGD PMID:7791755 PMID:19558367 PMID:21336257 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Cnot8 CCR4-NOT transcription complex, subunit 8 part_of ISO (PMID:19558367) RGD PMID:19558367 NCBI chr10:42,281,614...42,294,740
Ensembl chr10:42,281,722...42,294,730 		JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 part_of ISO
IEA
ISS		 (PMID:19558367)
GO_REF:0000002
GO_REF:0000024		 RGD
InterPro
UniProt		 PMID:19558367 GO_REF:0000002 GO_REF:0000024 NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100 		JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 part_of ISO (PMID:21336257) RGD PMID:21336257 NCBI chr 1:234,749,138...234,931,219
Ensembl chr 1:234,751,733...234,931,560 		JBrowse link
G ENSRNOG00000068058 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr16:17,898,135...17,898,773 JBrowse link
G Patl1 PAT1 homolog 1, processing body mRNA decay factor located_in ISS
ISO		 GO_REF:0000024
(PMID:20584987)		 UniProt
RGD		 PMID:20584987 GO_REF:0000024 NCBI chr 1:208,831,115...208,862,904
Ensembl chr 1:208,831,115...208,862,857 		JBrowse link
G Tnks1bp1 tankyrase 1 binding protein 1 part_of ISO (PMID:19558367) RGD PMID:19558367 NCBI chr 3:70,135,335...70,160,071
Ensembl chr 3:70,137,837...70,160,038 		JBrowse link
G Tob1 transducer of ErbB-2.1 part_of ISO
ISS
IEA		 (PMID:21336257)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:21336257 GO_REF:0000024 GO_REF:0000107 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215 		JBrowse link
G Zfp36 zinc finger protein 36 part_of
located_in		 IEA
ISO
ISS		 GO_REF:0000107
(MGI:5795819|PMID:20595389)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:20595389 GO_REF:0000024 GO_REF:0000107 MGI:5795819 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
CCR4-NOT core complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot1 CCR4-NOT transcription complex, subunit 1 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574 		JBrowse link
G Cnot2 CCR4-NOT transcription complex, subunit 2 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:52,130,445...52,222,338
Ensembl chr 7:52,130,441...52,223,575 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Cnot8 CCR4-NOT transcription complex, subunit 8 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:42,281,614...42,294,740
Ensembl chr10:42,281,722...42,294,730 		JBrowse link
G Cnot9 CCR4-NOT transcription complex subunit 9 part_of IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 9:76,084,269...76,109,111
Ensembl chr 9:76,084,334...76,109,100 		JBrowse link
G ENSRNOG00000068058 part_of IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr16:17,898,135...17,898,773 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21392
    protein-containing complex 6987
      intracellular protein-containing complex 987
        CCR4-NOT complex 17
          CCR4-NOT core complex 7
paths to the root