signal release - Ontology Report - Rat Genome Database

GO_REF:0000107

NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188

acetylcholine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC44A4

solute carrier family 44 member 4

involved_in

GO_REF:0000107

NCBI chr 6:31,526,660...31,542,165
Ensembl chr 6:32,413,441...32,428,550

aldosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

WNK4

WNK lysine deficient protein kinase 4

involved_in

GO_REF:0000107

NCBI chr17:14,520,448...14,537,799
Ensembl chr17:14,746,365...14,762,423

calcium ion-regulated exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CACNA1A

calcium voltage-gated channel subunit alpha1 A

acts_upstream_of_or_within

(MGI:1353373|PMID:10670432)

PMID:10670432

MGI:1353373

NCBI chr19:12,769,586...13,189,022
Ensembl chr19:13,507,102...13,804,729

DOC2B

double C2 domain beta

involved_in

PMID:20150444
(MGI:4439222|PMID:20150444)

PMID:20150444

MGI:4439222 RGD:8554647

NCBI chr17:19,854...58,336

RIMS1

regulating synaptic membrane exocytosis 1

acts_upstream_of_or_within

(MGI:3703478|PMID:17124501)

PMID:17124501

MGI:3703478

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

RIMS2

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within

(MGI:3703478|PMID:17124501)

PMID:17124501

MGI:3703478

NCBI chr 8:100,156,403...100,894,128

synaptosome associated protein 25

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

STX1B

syntaxin 1B

involved_in

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

synaptotagmin 1

acts_upstream_of_or_within
involved_in

(MGI:5141208|PMID:21521611)

PMID:21521611

GO_REF:0000107 MGI:5141208

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

SYT7

synaptotagmin 7

involved_in

(MGI:5707519|PMID:26738595)

PMID:26738595

MGI:5707519

NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375

calcium-dependent activation of synaptic vesicle fusion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DOC2A

double C2 domain alpha

involved_in

GO_REF:0000107

Ensembl chr16:30,378,922...30,384,142

DOC2B

double C2 domain beta

involved_in

PMID:20150444 PMID:22036572

(MGI:4439222|PMID:20150444)
PMID:22036572

SynGO

MGI:4439222 RGD:155230732

NCBI chr17:19,854...58,336

synaptotagmin 1

involved_in

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

SYT2

synaptotagmin 2

involved_in

(MGI:3695515|PMID:17192432)

SynGO

PMID:17192432

MGI:3695515

NCBI chr 1:178,187,872...178,308,522
Ensembl chr 1:182,490,401...182,538,123

SYT7

synaptotagmin 7

involved_in

(MGI:5554634|PMID:24267651)

SynGO

PMID:24267651

MGI:5554634

NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375

SYT9

synaptotagmin 9

involved_in

GO_REF:0000107

NCBI chr11:7,350,612...7,565,272
Ensembl chr11:7,032,803...7,247,187

corticosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KCNQ1

potassium voltage-gated channel subfamily Q member 1

involved_in

GO_REF:0000107

NCBI chr11:2,469,750...2,874,467

SELENOM

selenoprotein M

acts_upstream_of_or_within
involved_in

(MGI:5527224|PMID:23880772)

PMID:23880772

GO_REF:0000107 MGI:5527224

NCBI chr22:12,128,513...12,131,653
Ensembl chr22:29,966,602...29,969,137

corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AQP1

aquaporin 1 (Colton blood group)

acts_upstream_of_or_within

(MGI:3805139|PMID:18511498)

PMID:18511498

MGI:3805139

NCBI chr 7:31,524,933...31,538,602
Ensembl chr 7:31,644,331...31,658,141

CRHR1

corticotropin releasing hormone receptor 1

involved_in

(MGI:1267130|PMID:9655498)

PMID:9655498

MGI:1267130

NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208

dopamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHRNB2

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of

(MGI:1194464|PMID:9428762)

PMID:9428762

MGI:1194464

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

KPNA4

karyopherin subunit alpha 4

involved_in
acts_upstream_of_positive_effect

(PMID:32273471)

Ensembl
UniProt

PMID:32273471

GO_REF:0000107

NCBI chr 3:157,521,009...157,586,790
Ensembl chr 3:165,572,140...165,635,135

PINK1

PTEN induced kinase 1

acts_upstream_of
involved_in

(MGI:3715376|PMID:17563363)

PMID:17563363

GO_REF:0000107 MGI:3715376

NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560

TGM2

transglutaminase 2

involved_in
acts_upstream_of_positive_effect

(PMID:32273471)

Ensembl
UniProt

PMID:32273471

GO_REF:0000107

NCBI chr20:34,450,845...34,488,106
Ensembl chr20:35,561,819...35,599,042

evoked neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB3A

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

fast, calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 1

involved_in

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

follicle-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CGA

glycoprotein hormones, alpha polypeptide

acts_upstream_of_or_within

(MGI:1316794|PMID:12114718)

PMID:12114718

MGI:1316794

NCBI chr 6:84,962,974...84,972,638
Ensembl chr 6:88,236,206...88,247,300

TBX3

T-box transcription factor 3

involved_in

GO_REF:0000107

NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316

gamma-aminobutyric acid secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

neurofibromin 1

acts_upstream_of_or_within
involved_in

(MGI:5620820|PMID:25242307)

GO_REF:0000107 MGI:5620820

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

PAK1

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

(MGI:5620820|PMID:25242307)

MGI:5620820

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

ghrelin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

free fatty acid receptor 4

involved_in

GO_REF:0000107

NCBI chr10:90,312,647...90,336,115
Ensembl chr10:93,823,004...93,860,262

growth hormone secretagogue receptor

NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202

glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL6

interleukin 6

involved_in

(MGI:3807360|PMID:18719127)

PMID:18719127

MGI:3807360

NCBI chr 7:23,415,922...23,420,767

glutamate secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

neurofibromin 1

acts_upstream_of_or_within
involved_in

(MGI:5620820|PMID:25242307)

GO_REF:0000107 MGI:5620820

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

PAK1

p21 (RAC1) activated kinase 1

acts_upstream_of_or_within

(MGI:5620820|PMID:25242307)

MGI:5620820

NCBI chr11:72,372,577...72,524,817
Ensembl chr11:76,015,998...76,104,197

glycine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

SLC6A9

solute carrier family 6 member 9

acts_upstream_of_or_within

(MGI:5523768|PMID:22988142)

PMID:22988142

MGI:5523768

NCBI chr 1:43,298,326...43,333,345
Ensembl chr 1:44,664,839...44,704,882

gonadotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NIBAN2

niban apoptosis regulator 2

involved_in

GO_REF:0000107

NCBI chr 9:98,625,411...98,689,077
Ensembl chr 9:127,299,475...127,371,459

growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CDK16

cyclin dependent kinase 16

involved_in

GO_REF:0000107

NCBI chr X:39,655,119...39,666,878
Ensembl chr X:47,512,647...47,524,742

growth hormone releasing hormone

involved_in

GO_REF:0000107

NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240

growth hormone releasing hormone receptor

involved_in

GO_REF:0000107

NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200

growth hormone secretagogue receptor

involved_in

GO_REF:0000107

NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202

RAB1A

RAB1A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr2A:65,149,922...65,193,305
Ensembl chr2A:66,274,809...66,318,290

histamine secretion by mast cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BTK

Bruton tyrosine kinase

NCBI chr X:90,551,874...90,588,786
Ensembl chr X:100,684,017...100,725,187

LYN

LYN proto-oncogene, Src family tyrosine kinase

NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287

RAB44

RAB44, member RAS oncogene family

acts_upstream_of_or_within
involved_in

(MGI:6693988|PMID:32238914)

PMID:32238914

GO_REF:0000107 MGI:6693988

NCBI chr 6:36,260,088...36,295,723
Ensembl chr 6:37,462,355...37,490,330

SLC18A2

solute carrier family 18 member A2

involved_in

GO_REF:0000107

NCBI chr10:113,823,005...113,862,451
Ensembl chr10:117,250,639...117,290,064

SNAP23

synaptosome associated protein 23

involved_in

GO_REF:0000107

NCBI chr15:21,456,247...21,494,340
Ensembl chr15:39,612,445...39,650,759

YWHAZ

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

NCBI chr 8:97,560,251...97,595,117
Ensembl chr 8:99,730,393...99,762,990

histamine secretion mediated by IgE immunoglobulin

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

RAB44

RAB44, member RAS oncogene family

acts_upstream_of_or_within
involved_in

(MGI:6693988|PMID:32238914)

PMID:32238914

GO_REF:0000107 MGI:6693988

NCBI chr 6:36,260,088...36,295,723
Ensembl chr 6:37,462,355...37,490,330

hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CREB1

cAMP responsive element binding protein 1

involved_in

GO_REF:0000107

NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130

free fatty acid receptor 4

involved_in

GO_REF:0000107

NCBI chr10:90,312,647...90,336,115
Ensembl chr10:93,823,004...93,860,262

growth hormone releasing hormone

involved_in

GO_REF:0000107

NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240

growth hormone releasing hormone receptor

involved_in

GO_REF:0000107

NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200

LTBP4

latent transforming growth factor beta binding protein 4

involved_in

GO_REF:0000107

NCBI chr19:37,637,509...37,674,791
Ensembl chr19:46,144,485...46,181,636

RAPGEF4

Rap guanine nucleotide exchange factor 4

involved_in

GO_REF:0000107

NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644

syntaxin 1A

involved_in

GO_REF:0000107

Ensembl chr 7:80,852,495...80,862,255

insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR1C

activin A receptor type 1C

acts_upstream_of
involved_in

(MGI:3796011|PMID:18480258)

PMID:18480258

GO_REF:0000107 MGI:3796011

NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151

ACVR2B

activin A receptor type 2B

acts_upstream_of_or_within

(MGI:3758991|PMID:17849440)

PMID:17849440

MGI:3758991

NCBI chr 3:38,350,838...38,389,839
Ensembl chr 3:38,633,093...38,662,063

ADCYAP1

adenylate cyclase activating polypeptide 1

involved_in

(MGI:5525944|PMID:23913443)

PMID:23913443

MGI:5525944

NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749

annexin A1

NCBI chr 9:51,647,404...51,665,990
Ensembl chr 9:71,929,728...71,948,779

ANXA7

annexin A7

acts_upstream_of

(MGI:4459350|PMID:20440069)

PMID:20440069

MGI:4459350

NCBI chr10:69,923,353...69,962,980
Ensembl chr10:72,381,447...72,420,749

CACNA1C

calcium voltage-gated channel subunit alpha1 C

acts_upstream_of_or_within

(MGI:2670808|PMID:12881419)

PMID:12881419

MGI:2670808

NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826

CCKAR

cholecystokinin A receptor

NCBI chr 4:20,881,340...20,890,986
Ensembl chr 4:26,157,702...26,166,773

CPLX1

complexin 1

involved_in

GO_REF:0000107

NCBI chr 4:889,037...930,046
Ensembl chr 4:819,833...858,953

CPLX3

complexin 3

involved_in

GO_REF:0000107

NCBI chr15:53,769,138...53,774,330
Ensembl chr15:73,386,826...73,391,991

DGAT1

diacylglycerol O-acyltransferase 1

NCBI chr 8:141,079,948...141,090,619
Ensembl chr 8:144,064,587...144,080,155

FAM3B

FAM3 metabolism regulating signaling molecule B

involved_in

GO_REF:0000107

NCBI chr21:27,650,185...27,692,249
Ensembl chr21:40,979,149...41,020,089

FFAR1

free fatty acid receptor 1

acts_upstream_of_or_within
involved_in

(MGI:3713161|PMID:17395749)

PMID:17395749

GO_REF:0000107 MGI:3713161

NCBI chr19:32,298,259...32,300,601
Ensembl chr19:41,034,905...41,035,807

FKBP1B

FKBP prolyl isomerase 1B

involved_in
acts_upstream_of_or_within

(MGI:3795616|PMID:18466757)

PMID:18466757

GO_REF:0000107 MGI:3795616

NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082

GLP1R

glucagon like peptide 1 receptor

involved_in

PMID:10362617

NCBI chr 6:38,637,838...38,680,423
Ensembl chr 6:39,823,373...39,855,784

GPR119

G protein-coupled receptor 119

acts_upstream_of_or_within
involved_in

(MGI:3522385|PMID:15607732)

PMID:15607732

GO_REF:0000107 MGI:3522385

NCBI chr X:119,511,372...119,512,611
Ensembl chr X:129,803,383...129,804,390

G protein-coupled receptor 39

acts_upstream_of

(MGI:4355293|PMID:19213841)

PMID:19213841

MGI:4355293

NCBI chr2B:27,429,851...27,431,292

GPR68

G protein-coupled receptor 68

acts_upstream_of
involved_in

(MGI:5444590|PMID:22733973)

PMID:22733973

GO_REF:0000107 MGI:5444590

NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806

HNF1A

HNF1 homeobox A

acts_upstream_of_or_within
involved_in

PMID:9566924 PMID:9593777 PMID:9733737 PMID:15142986

(MGI:1202489|PMID:9566924), (MGI:1298140|PMID:9733737)
(MGI:1266996|PMID:9593777), (MGI:3047439|PMID:15142986)

MGI
InterPro
Ensembl

GO_REF:0000002 GO_REF:0000107 MGI:1202489 MGI:1266996 MGI:1298140 MGI:3047439

NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911

HNF1B

HNF1 homeobox B

acts_upstream_of_or_within
involved_in

(MGI:3047439|PMID:15142986)

MGI
Ensembl
InterPro

PMID:15142986

GO_REF:0000002 GO_REF:0000107 MGI:3047439

NCBI chr17:19,333,485...19,392,147
Ensembl chr17:19,633,424...19,691,863

HTT

huntingtin

acts_upstream_of_or_within

(MGI:1333401|PMID:10078572)

PMID:10078572

MGI:1333401

NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730

ILDR2

immunoglobulin like domain containing receptor 2

acts_upstream_of_or_within
involved_in

(MGI:3804573|PMID:18654634)

PMID:18654634

GO_REF:0000107 MGI:3804573

NCBI chr 1:142,315,984...142,395,729
Ensembl chr 1:146,125,919...146,181,822

IRS1

insulin receptor substrate 1

NOT|acts_upstream_of_or_within

(MGI:86285|PMID:9062343)

PMID:9062343

MGI:86285

NCBI chr2B:113,973,191...114,041,127
Ensembl chr2B:232,849,239...232,852,967

LEP

leptin

acts_upstream_of_or_within
involved_in

(MGI:3770192|PMID:16141392)

PMID:16141392

GO_REF:0000107 MGI:3770192

NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519

LOC100977566

cytochrome b5 reductase 4

acts_upstream_of_or_within
involved_in

(MGI:3047191|PMID:15247412)

PMID:15247412

GO_REF:0000107 MGI:3047191

NCBI chr 6:81,756,292...81,864,365
Ensembl chr 6:85,030,058...85,130,948

LOC100991079

interleukin-1 receptor antagonist protein

acts_upstream_of_or_within
involved_in

(MGI:2675567|PMID:12975454)

PMID:12975454

GO_REF:0000107 MGI:2675567

NCBI chr2A:88,991,646...89,008,013
Ensembl chr2A:114,061,182...114,078,839

MAFA

MAF bZIP transcription factor A

involved_in

(PMID:17941991)

PMID:17941991

NCBI chr 8:140,178,322...140,181,152

MC4R

melanocortin 4 receptor

acts_upstream_of_or_within
involved_in

(MGI:3770192|PMID:16141392)

PMID:16141392

GO_REF:0000107 MGI:3770192

NCBI chr18:53,744,172...53,747,282
Ensembl chr18:57,069,259...57,070,257

MYO5A

myosin VA

acts_upstream_of_or_within

(MGI:3589494|PMID:15788565)

PMID:15788565

MGI:3589494

NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319

NEUROD1

neuronal differentiation 1

involved_in

(PMID:17941991)

PMID:17941991

NCBI chr2B:68,939,341...68,943,516

NNAT

neuronatin

acts_upstream_of

(MGI:3614320|PMID:15793245)

PMID:15793245

MGI:3614320

NCBI chr20:33,842,071...33,845,575
Ensembl chr20:34,955,234...34,959,493

PARK7

Parkinsonism associated deglycase

involved_in

(MGI:5908331|PMID:22611253)

PMID:22611253

MGI:5908331

NCBI chr 1:6,722,260...6,745,915
Ensembl chr 1:7,969,280...7,993,271

PCLO

piccolo presynaptic cytomatrix protein

acts_upstream_of_or_within

(MGI:2447935|PMID:12401793)

PMID:12401793

MGI:2447935

NCBI chr 7:74,714,364...75,126,518

PDX1

pancreatic and duodenal homeobox 1

involved_in

(PMID:17941991)

PMID:17941991

NCBI chr13:9,199,572...9,206,202

PRKCE

protein kinase C epsilon

acts_upstream_of
involved_in

(MGI:2675178|PMID:12837755)

PMID:12837755

GO_REF:0000107 MGI:2675178

NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313

PTPRN

protein tyrosine phosphatase receptor type N

involved_in

GO_REF:0000107

NCBI chr2B:106,547,156...106,567,056
Ensembl chr2B:225,138,887...225,206,700

RAB3A

RAB3A, member RAS oncogene family

involved_in

GO_REF:0000107

NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768

RAPGEF4

Rap guanine nucleotide exchange factor 4

acts_upstream_of_or_within
involved_in

(MGI:2154654|PMID:11598134), (MGI:2447935|PMID:12401793)

PMID:11598134 PMID:12401793

GO_REF:0000107 MGI:2154654 MGI:2447935

NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644

RIMS2

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within
involved_in

(MGI:4821020|PMID:20674857)
(MGI:2154654|PMID:11598134)

PMID:11598134 PMID:20674857

MGI:2154654 MGI:4821020

NCBI chr 8:100,156,403...100,894,128

SERP1

stress associated endoplasmic reticulum protein 1

acts_upstream_of
involved_in

(MGI:3619104|PMID:16415102)

PMID:16415102

GO_REF:0000107 MGI:3619104

NCBI chr 3:147,559,607...147,564,668
Ensembl chr 3:155,133,115...155,137,241

SLC18A2

solute carrier family 18 member A2

NCBI chr10:113,823,005...113,862,451
Ensembl chr10:117,250,639...117,290,064

SLC30A8

solute carrier family 30 member 8

involved_in

PMID:19479076

GO_REF:0000107 RGD:2315022

NCBI chr 8:113,624,785...113,851,633
Ensembl chr 8:116,223,595...116,394,095

SMAD2

SMAD family member 2

acts_upstream_of_or_within
involved_in

(MGI:3758991|PMID:17849440)

PMID:17849440

GO_REF:0000107 MGI:3758991

NCBI chr18:41,213,001...41,309,902
Ensembl chr18:44,580,905...44,668,530

SNX19

sorting nexin 19

acts_upstream_of_or_within
involved_in

(MGI:5605377|PMID:24843546)

PMID:24843546

GO_REF:0000107 MGI:5605377

NCBI chr11:125,691,537...125,732,206
Ensembl chr11:129,581,876...129,622,517

SREBF1

sterol regulatory element binding transcription factor 1

acts_upstream_of
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045

syntaxin 1A

involved_in

GO_REF:0000107

Ensembl chr 7:80,852,495...80,862,255

STXBP3

syntaxin binding protein 3

acts_upstream_of_or_within
involved_in

(MGI:4352814|PMID:19188424)

PMID:19188424

GO_REF:0000107 MGI:4352814

NCBI chr 1:111,120,487...111,185,669
Ensembl chr 1:110,287,374...110,351,616

SYTL4

synaptotagmin like 4

acts_upstream_of
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr X:89,885,478...89,941,381
Ensembl chr X:100,024,434...100,051,663

VGF

VGF nerve growth factor inducible

acts_upstream_of_or_within

(MGI:3770192|PMID:16141392)

PMID:16141392

MGI:3770192

NCBI chr 7:93,302,956...93,307,892

insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ATG7

autophagy related 7

acts_upstream_of

(MGI:5544155|PMID:24105478)

PMID:24105478

MGI:5544155

NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398

CCDC186

coiled-coil domain containing 186

acts_upstream_of_or_within
involved_in

(MGI:6102228|PMID:27293546)

PMID:27293546

GO_REF:0000107 MGI:6102228

NCBI chr10:110,720,243...110,774,362
Ensembl chr10:114,156,401...114,194,141

CLTRN

collectrin, amino acid transport regulator

acts_upstream_of_positive_effect
involved_in

(PMID:16330323)

GO_Central
Ensembl

PMID:16330323

GO_REF:0000107

NCBI chr X:8,255,666...8,293,354
Ensembl chr X:15,535,069...15,575,268

FKBP1B

FKBP prolyl isomerase 1B

acts_upstream_of
involved_in

(MGI:4421103|PMID:19805579)

PMID:19805579

GO_REF:0000107 MGI:4421103

NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082

G protein-coupled receptor 39

acts_upstream_of

(MGI:4437975|PMID:19213833)

PMID:19213833

MGI:4437975

NCBI chr2B:27,429,851...27,431,292

HIF1A

hypoxia inducible factor 1 subunit alpha

acts_upstream_of
involved_in

(MGI:4459348|PMID:20440072)

PMID:20440072

GO_REF:0000107 MGI:4459348

NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885

PTPRN

protein tyrosine phosphatase receptor type N

involved_in

(MGI:3624867|PMID:12031972), (MGI:5141326|PMID:21732083)

PMID:12031972 PMID:21732083

MGI:3624867 MGI:5141326

NCBI chr2B:106,547,156...106,567,056
Ensembl chr2B:225,138,887...225,206,700

PTPRN2

protein tyrosine phosphatase receptor type N2

involved_in

GO_REF:0000107

NCBI chr 7:149,158,513...150,390,077
Ensembl chr 7:160,851,703...161,756,325

RAB11B

RAB11B, member RAS oncogene family

involved_in

(MGI:4352608|PMID:19335615)

PMID:19335615

MGI:4352608

NCBI chr19:7,676,095...7,690,177

RAB11FIP2

RAB11 family interacting protein 2

involved_in

GO_REF:0000107

NCBI chr10:114,577,851...114,619,808
Ensembl chr10:117,970,693...118,044,607

RAB11FIP5

RAB11 family interacting protein 5

involved_in

(MGI:4352608|PMID:19335615)

PMID:19335615

MGI:4352608

NCBI chr2A:73,126,262...73,165,892
Ensembl chr2A:74,620,821...74,657,419

RAF1

Raf-1 proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within
involved_in

(MGI:5306883|PMID:21817126)

PMID:21817126

GO_REF:0000107 MGI:5306883

NCBI chr 3:12,510,084...12,590,598
Ensembl chr 3:12,853,415...12,932,871

RBM4

RNA binding motif protein 4

acts_upstream_of_or_within

(MGI:5466631|PMID:23129807)

PMID:23129807

MGI:5466631

NCBI chr11:61,996,221...62,026,007
Ensembl chr11:65,298,404...65,349,183

SELENOT

selenoprotein T

acts_upstream_of_or_within
involved_in

(MGI:5525944|PMID:23913443)

PMID:23913443

GO_REF:0000107 MGI:5525944

NCBI chr 3:147,620,862...147,648,039
Ensembl chr 3:155,194,428...155,221,578

luteinizing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CGA

glycoprotein hormones, alpha polypeptide

acts_upstream_of_or_within

(MGI:1316794|PMID:12114718)

PMID:12114718

MGI:1316794

NCBI chr 6:84,962,974...84,972,638
Ensembl chr 6:88,236,206...88,247,300

FOXD1

forkhead box D1

involved_in

(MGI:5484943|PMID:23284914)

PMID:23284914

MGI:5484943

NCBI chr 5:41,867,118...41,870,497

TBX3

T-box transcription factor 3

involved_in

GO_REF:0000107

NCBI chr12:112,240,050...112,254,299
Ensembl chr12:115,620,002...115,631,316

TMF1

TATA element modulatory factor 1

acts_upstream_of_or_within
involved_in

(MGI:5469555|PMID:23000399)

PMID:23000399

GO_REF:0000107 MGI:5469555

NCBI chr 3:68,955,866...68,988,353
Ensembl chr 3:70,322,814...70,355,460

negative regulation of acetylcholine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

HTR6

5-hydroxytryptamine receptor 6

NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680

negative regulation of adiponectin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IL1B

interleukin 1 beta

involved_in

(MGI:3828398|PMID:16865359)

PMID:16865359

MGI:3828398

NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424

RAB11FIP1

RAB11 family interacting protein 1

involved_in

GO_REF:0000107

NCBI chr 8:37,159,466...37,200,147
Ensembl chr 8:34,336,553...34,356,333

RAB11FIP3

RAB11 family interacting protein 3

involved_in

(PMID:24040321)

RAB11 family interacting protein 5

involved_in

(PMID:24040321)

PMID:24040321

NCBI chr2A:73,126,262...73,165,892
Ensembl chr2A:74,620,821...74,657,419

negative regulation of corticosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

neuregulin 1

NCBI chr 8:30,954,852...32,084,411
Ensembl chr 8:29,050,222...29,263,977

translocator protein

NCBI chr22:24,034,918...24,046,370
Ensembl chr22:42,233,619...42,244,930

negative regulation of corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CRHBP

corticotropin releasing hormone binding protein

involved_in

GO_REF:0000107

NCBI chr 5:38,327,305...38,343,901
Ensembl chr 5:38,845,925...38,869,549

negative regulation of cortisol secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within

(MGI:3513751|PMID:15520383)

NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762

negative regulation of dopamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420

complement C5

NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856

CNR1

cannabinoid receptor 1

NCBI chr 6:86,017,141...86,044,889

dopamine receptor D2

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

ENTPD1

ectonucleoside triphosphate diphosphohydrolase 1

NCBI chr10:92,365,267...92,511,852
Ensembl chr10:95,828,094...95,983,257

GABBR1

gamma-aminobutyric acid type B receptor subunit 1

NCBI chr 6:29,405,026...29,437,108
Ensembl chr 6:30,065,119...30,095,304

myosin VA

NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319

SYT11

synaptotagmin 11

involved_in

GO_REF:0000107

NCBI chr 1:131,193,999...131,218,752
Ensembl chr 1:135,026,032...135,046,943

negative regulation of follicle-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone receptor 2

NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220

INHA

inhibin subunit alpha

immature male rats
female rats during diestrus-1

PMID:2500324 PMID:8015360

RGD:2290442 RGD:2290444

NCBI chr2B:106,828,948...106,832,993
Ensembl chr2B:225,419,176...225,423,386

INHBB

inhibin subunit beta B

involved_in

(PMID:3122219)

PMID:3122219

NCBI chr2B:7,278,944...7,284,632

urocortin 2

NCBI chr 3:48,484,628...48,485,179

negative regulation of glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CART prepropeptide

NCBI chr 5:43,591,683...43,593,586
Ensembl chr 5:44,236,114...44,238,229

corticotropin releasing hormone

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

LEP

leptin

involved_in

GO_REF:0000107

NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519

nucleobindin 2

NCBI chr11:17,331,742...17,404,682
Ensembl chr11:17,036,038...17,072,447

negative regulation of glucocorticoid secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CRY1

cryptochrome circadian regulator 1

involved_in

GO_REF:0000107

NCBI chr12:104,558,874...104,658,833
Ensembl chr12:107,954,262...108,052,484

CRY2

cryptochrome circadian regulator 2

involved_in

GO_REF:0000107

NCBI chr11:45,801,504...45,837,357
Ensembl chr11:46,293,717...46,329,759

negative regulation of gonadotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NPVF

neuropeptide VF precursor

involved_in

GO_REF:0000107

NCBI chr 7:25,883,679...25,887,596
Ensembl chr 7:25,489,577...25,493,126

negative regulation of growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KALRN

kalirin RhoGEF kinase

acts_upstream_of_or_within
involved_in

(MGI:5551307|PMID:23116210)

PMID:23116210

GO_REF:0000107 MGI:5551307

NCBI chr 3:121,138,136...121,828,723
Ensembl chr 3:128,225,413...128,720,441

MADD

MAP kinase activating death domain

NCBI chr11:47,216,006...47,276,422
Ensembl chr11:47,773,733...47,828,360

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within

(MGI:3513751|PMID:15520383)

NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762

sirtuin 1

NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069

SSTR1

somatostatin receptor 1

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr14:18,968,969...18,973,560
Ensembl chr14:37,329,309...37,330,484

SSTR2

somatostatin receptor 2

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr17:67,093,013...67,099,086
Ensembl chr17:72,553,506...72,554,615

SSTR3

somatostatin receptor 3

involved_in

(PMID:16543371)

PMID:16543371

NCBI chr22:18,116,993...18,125,170
Ensembl chr22:35,954,232...35,955,488

negative regulation of hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADIPOQ

adiponectin, C1Q and collagen domain containing

NCBI chr 3:183,876,051...183,889,723
Ensembl chr 3:192,341,320...192,354,885

ADORA1

adenosine A1 receptor

gastrin

NCBI chr 1:178,728,751...178,769,066
Ensembl chr 1:183,023,466...183,063,760

endothelin 1

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

endothelin 2

NCBI chr 1:40,777,582...40,783,410
Ensembl chr 1:42,092,811...42,098,721

endothelin 3

NCBI chr20:55,652,770...55,678,486
Ensembl chr20:57,012,926...57,038,570

FGF23

fibroblast growth factor 23

involved_in

PMID:17992255

NCBI chr12:4,479,116...4,488,797
Ensembl chr12:4,400,802...4,412,000

IL11

interleukin 11

acts_upstream_of_or_within
involved_in

(PMID:7867561)

GO_REF:0000107

NCBI chr19:52,407,730...52,426,445
Ensembl chr19:61,096,275...61,101,837

IL6

interleukin 6

acts_upstream_of_or_within

(MGI:71439|PMID:7867561)

MGI:71439

NCBI chr 7:23,415,922...23,420,767

LIF

LIF interleukin 6 family cytokine

acts_upstream_of_or_within
involved_in

(PMID:7867561)

GO_REF:0000107

NCBI chr22:11,276,576...11,282,972
Ensembl chr22:29,078,862...29,095,608

NMB

neuromedin B

thyrotropin (TSH); anterior pituitary gland of euthyroid and hyperthyroid rats

PMID:1557409

RGD:1642347

NCBI chr15:63,322,869...63,326,989

NPY1R

neuropeptide Y receptor Y1

NCBI chr 4:155,583,870...155,604,336
Ensembl chr 4:167,372,310...167,381,597

OSM

oncostatin M

acts_upstream_of_or_within
involved_in

(PMID:7867561)

GO_REF:0000107

NCBI chr22:11,298,965...11,303,009
Ensembl chr22:29,101,085...29,105,081

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within

(MGI:3513751|PMID:15520383)

NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762

urocortin

ghrelin

NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669

negative regulation of insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCC8

ATP binding cassette subfamily C member 8

involved_in

PMID:15163199 PMID:16924481 PMID:25771886

(MGI:3831492|PMID:16924481)
(MGI:7333031|PMID:25771886)

RGD
MGI

MGI:3831492 MGI:7333031 RGD:1598646

NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870

ACVR1C

activin A receptor type 1C

acts_upstream_of_or_within
involved_in

(MGI:3796011|PMID:18480258)

PMID:18480258

GO_REF:0000107 MGI:3796011

NCBI chr2B:44,785,808...44,883,977
Ensembl chr2B:162,034,161...162,124,151

ADRA2A

adrenoceptor alpha 2A

involved_in

PMID:1898674 PMID:10952463 PMID:17992256

(PMID:10952463)
(MGI:3772319|PMID:17992256), (MGI:7343840|PMID:1898674)
(MGI:7343840|PMID:1898674)

BHF-UCL
MGI

MGI:3772319 MGI:7343840

NCBI chr10:107,669,860...107,673,685

BMP8A

bone morphogenetic protein 8a

involved_in

(PMID:22579288)

PMID:22579288

NCBI chr 1:38,776,557...38,815,210

CCN3

cellular communication network factor 3

involved_in

GO_REF:0000107

NCBI chr 8:116,105,935...116,114,241
Ensembl chr 8:118,855,445...118,865,039

dopamine receptor D2

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265

FAM3D

FAM3 metabolism regulating signaling molecule D

involved_in

GO_REF:0000107

NCBI chr 3:58,564,083...58,685,370
Ensembl chr 3:59,973,612...59,993,727

FBN1

fibrillin 1

involved_in

(MGI:6442875|PMID:30997682)

PMID:30997682

MGI:6442875

NCBI chr15:27,358,780...27,593,539
Ensembl chr15:45,682,450...45,918,111

FFAR2

free fatty acid receptor 2

involved_in

GO_REF:0000107

NCBI chr19:32,394,401...32,398,730
Ensembl chr19:41,132,599...41,133,591

FOXO1

forkhead box O1

involved_in

(MGI:2388494|PMID:12219087), (MGI:6101624|PMID:27457971)

PMID:12219087 PMID:27457971

MGI:2388494 MGI:6101624

NCBI chr13:21,763,729...21,874,279

ghrelin and obestatin prepropeptide

acts_upstream_of_or_within
involved_in

(MGI:3709118|PMID:17130496)

PMID:17130496

GO_REF:0000107 MGI:3709118 RGD:8553721

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

growth hormone secretagogue receptor

acts_upstream_of_or_within

PMID:17130496

NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202

GNAO1

G protein subunit alpha o1

involved_in

(MGI:4941424|PMID:20622165)
(MGI:4887503|PMID:21220323)

PMID:20622165 PMID:21220323

MGI:4887503 MGI:4941424

NCBI chr16:36,473,852...36,643,789
Ensembl chr16:55,606,920...55,776,619

GNAZ

G protein subunit alpha z

involved_in

(MGI:3775331|PMID:18096703)

PMID:18096703

MGI:3775331

Ensembl chr22:21,719,169...21,746,851

HADH

hydroxyacyl-CoA dehydrogenase

NCBI chr 4:100,495,205...100,540,589
Ensembl chr 4:111,067,336...111,113,868

HDAC1

histone deacetylase 1

NCBI chr 1:31,578,373...31,619,970
Ensembl chr 1:32,585,791...32,626,410

INHBB

inhibin subunit beta B

acts_upstream_of_or_within

(MGI:3796011|PMID:18480258)

PMID:18480258

MGI:3796011

NCBI chr2B:7,278,944...7,284,632

IRS1

insulin receptor substrate 1

involved_in

GO_REF:0000107

NCBI chr2B:113,973,191...114,041,127
Ensembl chr2B:232,849,239...232,852,967

KCNB1

potassium voltage-gated channel subfamily B member 1

involved_in

GO_REF:0000107

NCBI chr20:45,636,371...45,821,536
Ensembl chr20:46,776,274...46,885,521

KCNJ11

potassium inwardly rectifying channel subfamily J member 11

involved_in

GO_REF:0000107

NCBI chr11:17,440,522...17,444,075
Ensembl chr11:17,127,557...17,128,729

KCNQ1

potassium voltage-gated channel subfamily Q member 1

NCBI chr11:2,469,750...2,874,467

LOC100994502

free fatty acid receptor 3

involved_in

GO_REF:0000107

NCBI chr19:32,305,112...32,307,223

MIDN

midnolin

acts_upstream_of_or_within

PMID:24187134

melatonin receptor 1A

NCBI chr 4:178,693,869...178,720,351
Ensembl chr 4:190,897,192...190,921,677

MTNR1B

melatonin receptor 1B

NCBI chr11:87,996,805...88,009,865
Ensembl chr11:91,491,822...91,504,652

NOS1

nitric oxide synthase 1

NCBI chr12:114,784,232...114,938,385
Ensembl chr12:118,163,655...118,314,005

NPFF

neuropeptide FF-amide peptide precursor

NCBI chr12:35,245,172...35,246,710
Ensembl chr12:36,030,805...36,031,591

phosphodiesterase 8B

NCBI chr 5:37,874,089...38,121,322
Ensembl chr 5:38,402,790...38,617,743

PFKL

phosphofructokinase, liver type

acts_upstream_of_or_within
involved_in

(MGI:1096000|PMID:9287040)

PMID:9287040

GO_REF:0000107 MGI:1096000

NCBI chr21:30,557,576...30,584,231
Ensembl chr21:43,857,052...43,878,380

PPP3CA

protein phosphatase 3 catalytic subunit alpha

involved_in

PMID:19965390

NCBI chr 4:93,447,095...93,770,339
Ensembl chr 4:104,113,520...104,435,394

PRKN

parkin RBR E3 ubiquitin protein ligase

acts_upstream_of_or_within
involved_in

(PMID:24187134)

PMID:24187134

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

PSMD9

proteasome 26S subunit, non-ATPase 9

involved_in

PMID:16099819

NCBI chr12:119,490,380...119,519,318
Ensembl chr12:122,859,940...122,887,703

PTGER3

prostaglandin E receptor 3

NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within

(MGI:3513751|PMID:15520383)

NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762

REST

RE1 silencing transcription factor

involved_in

GO_REF:0000107

NCBI chr 4:66,984,466...67,012,301
Ensembl chr 4:73,526,085...73,582,242

RPTOR

regulatory associated protein of MTOR complex 1

involved_in

(MGI:5619445|PMID:23092880)

PMID:23092880

MGI:5619445

NCBI chr17:74,973,420...75,389,339
Ensembl chr17:80,705,544...81,118,708

SFRP1

secreted frizzled related protein 1

involved_in

(PMID:17994217)

PMID:17994217

NCBI chr 8:40,507,027...40,555,053

SIRT4

sirtuin 4

acts_upstream_of_or_within
involved_in

(MGI:3769241|PMID:16959573)

PMID:16959573

GO_REF:0000107 MGI:3769241

NCBI chr12:117,867,453...117,887,968
Ensembl chr12:121,241,112...121,261,777

SREBF1

sterol regulatory element binding transcription factor 1

acts_upstream_of_or_within
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr17:33,458,196...33,484,643
Ensembl chr17:38,405,794...38,432,045

STXBP5L

syntaxin binding protein 5L

acts_upstream_of_or_within
involved_in

(MGI:5296997|PMID:21998599)

PMID:21998599

GO_REF:0000107 MGI:5296997

NCBI chr 3:118,022,061...118,529,311
Ensembl chr 3:124,932,110...125,434,515

SYTL4

synaptotagmin like 4

acts_upstream_of_or_within
involved_in

(MGI:3770077|PMID:16890542)

GO_REF:0000107 MGI:3770077

NCBI chr X:89,885,478...89,941,381
Ensembl chr X:100,024,434...100,051,663

urotensin 2

NCBI chr 1:6,609,104...6,616,966
Ensembl chr 1:7,854,687...7,864,688

VSNL1

visinin like 1

acts_upstream_of_or_within
involved_in

(MGI:3694336|PMID:16731532)

PMID:16731532

GO_REF:0000107 MGI:3694336

NCBI chr2A:17,525,561...17,641,277
Ensembl chr2A:17,703,086...17,767,274

negative regulation of insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADRA2A

adrenoceptor alpha 2A

involved_in

(PMID:19965390)

NCBI chr10:107,669,860...107,673,685

corticotropin releasing hormone receptor 2

NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220

ENY2

ENY2 transcription and export complex 2 subunit

NCBI chr 8:105,985,043...105,996,686
Ensembl chr 8:108,129,883...108,141,478

FKBP1B

FKBP prolyl isomerase 1B

acts_upstream_of_or_within
involved_in

(MGI:4421103|PMID:19805579)

PMID:19805579

GO_REF:0000107 MGI:4421103

NCBI chr2A:24,047,287...24,065,765
Ensembl chr2A:24,145,893...24,159,082

HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

NCBI chr 5:39,936,630...39,961,519
Ensembl chr 5:40,548,919...40,573,785

jagunal homolog 1

NCBI chr 3:9,835,123...9,838,398
Ensembl chr 3:10,183,760...10,187,064

KLF7

KLF transcription factor 7

involved_in

GO_REF:0000107

NCBI chr2B:94,307,334...94,399,553
Ensembl chr2B:212,448,337...212,525,403

MAP4K4

mitogen-activated protein kinase kinase kinase kinase 4

Ensembl chr2A:102,750,221...102,945,263

NDUFAF2

NADH:ubiquinone oxidoreductase complex assembly factor 2

acts_upstream_of_or_within

(MGI:5467193|PMID:22587331)

PMID:22587331

MGI:5467193

NCBI chr 5:52,843,931...53,053,671

phosphodiesterase 1C

NCBI chr 7:32,225,293...33,037,627
Ensembl chr 7:32,343,701...33,029,405

phosphodiesterase 3B

NCBI chr11:14,746,301...14,961,316
Ensembl chr11:14,437,060...14,648,616

phosphodiesterase 4C

NCBI chr19:17,683,455...17,709,936
Ensembl chr19:18,663,378...18,686,194

phosphodiesterase 8B

NCBI chr 5:37,874,089...38,121,322
Ensembl chr 5:38,402,790...38,617,743

PIM3

Pim-3 proto-oncogene, serine/threonine kinase

involved_in

GO_REF:0000107

NCBI chr22:30,186,716...30,190,270

PTPMT1

protein tyrosine phosphatase mitochondrial 1

NCBI chr11:47,515,304...47,521,529
Ensembl chr11:48,064,931...48,073,474

TBC1D1

TBC1 domain family member 1

NCBI chr 4:32,217,463...32,466,020
Ensembl chr 4:38,084,075...38,319,842

uncoupling protein 2

NCBI chr11:69,047,397...69,056,056
Ensembl chr11:72,354,529...72,363,185

negative regulation of luteinizing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

corticotropin releasing hormone receptor 2

NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220

OPRK1

opioid receptor kappa 1

NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577

TACR2

tachykinin receptor 2

NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224

urocortin 2

NCBI chr 3:48,484,628...48,485,179

negative regulation of neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASIC1

acid sensing ion channel subunit 1

acts_upstream_of_or_within
involved_in

(MGI:3841883|PMID:18094106)

PMID:18094106

GO_REF:0000107 MGI:3841883

NCBI chr12:38,672,253...38,698,247

neurofibromin 1

acts_upstream_of_or_within
involved_in

(MGI:3612345|PMID:16298082)

PMID:16298082

GO_REF:0000107 MGI:3612345

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

PNKD

PNKD metallo-beta-lactamase domain containing

involved_in
acts_upstream_of_or_within

(MGI:5634213|PMID:25730884)

PMID:25730884

GO_REF:0000107 MGI:5634213

NCBI chr2B:105,529,775...105,606,207
Ensembl chr2B:224,127,504...224,204,046

SLC30A1

solute carrier family 30 member 1

involved_in

PMID:16741752

NCBI chr 1:187,139,544...187,147,113

SYT4

synaptotagmin 4

involved_in

PMID:10397765

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

negative regulation of norepinephrine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AGTR2

angiotensin II receptor type 2

NCBI chr X:105,252,903...105,257,171
Ensembl chr X:115,671,594...115,672,685

complement C5

NCBI chr 9:92,069,574...92,202,513
Ensembl chr 9:120,426,354...120,523,856

corticotropin releasing hormone

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

corticotropin releasing hormone receptor 2

NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220

growth hormone secretagogue receptor

NCBI chr 3:169,448,217...169,458,602
Ensembl chr 3:177,633,039...177,638,202

P2RY1

purinergic receptor P2Y1

NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813

P2RY12

purinergic receptor P2Y12

NCBI chr 3:148,364,151...148,412,231

PTGER3

prostaglandin E receptor 3

NCBI chr 1:70,076,610...70,271,475
Ensembl chr 1:72,059,441...72,254,063

PTGS1

prostaglandin-endoperoxide synthase 1

NCBI chr 9:93,495,365...93,517,557
Ensembl chr 9:121,837,095...121,859,283

negative regulation of peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PPARG

peroxisome proliferator activated receptor gamma

involved_in

(MGI:5486574|PMID:11387233)

PMID:11387233

MGI:5486574

NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060

negative regulation of progesterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TP53

tumor protein p53

involved_in

(PMID:18703674)

PMID:18703674

NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120

negative regulation of prolactin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

annexin A5

NCBI chr 4:113,868,218...113,897,243
Ensembl chr 4:125,006,038...125,034,972

negative regulation of prostaglandin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACSL4

acyl-CoA synthetase long chain family member 4

involved_in

(PMID:21242590)

PMID:21242590

NCBI chr X:98,731,109...98,841,067
Ensembl chr X:109,206,964...109,310,914

ATP5PF

ATP synthase peripheral stalk subunit F6

PMID:11581303 PMID:19474762

RGD:13800898 RGD:13800911

NCBI chr21:12,169,567...12,180,717
Ensembl chr21:25,519,441...25,537,363

negative regulation of renin secretion into blood stream

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2R

coagulation factor II thrombin receptor

involved_in

GO_REF:0000107

NCBI chr 5:38,565,957...38,585,725
Ensembl chr 5:39,110,170...39,129,688

negative regulation of serotonin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CD300A

CD300a molecule

acts_upstream_of_or_within

(MGI:3721168|PMID:12874256)

PMID:12874256

MGI:3721168

NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928

CNR1

cannabinoid receptor 1

involved_in

PMID:30217553

NCBI chr 6:86,017,141...86,044,889

HRH3

histamine receptor H3

NCBI chr20:58,581,228...58,586,585
Ensembl chr20:59,901,327...59,909,901

HTR1B

5-hydroxytryptamine receptor 1B

involved_in

Ensembl
UniProt

GO_REF:0000104 GO_REF:0000107

NCBI chr 6:75,309,078...75,313,747
Ensembl chr 6:78,596,408...78,597,580

HTR7

5-hydroxytryptamine receptor 7

NCBI chr10:87,480,970...87,598,212
Ensembl chr10:91,009,941...91,125,158

monoamine oxidase B

NCBI chr X:36,217,710...36,333,516
Ensembl chr X:44,042,000...44,157,941

negative regulation of somatostatin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

free fatty acid receptor 4

involved_in

GO_REF:0000107

NCBI chr10:90,312,647...90,336,115
Ensembl chr10:93,823,004...93,860,262

GAL

galanin and GMAP prepropeptide

involved_in

(PMID:8837218)

PMID:8837218

NCBI chr11:63,770,758...63,777,421
Ensembl chr11:67,075,547...67,081,696

IRS1

insulin receptor substrate 1

involved_in

PMID:12435589

NCBI chr2B:113,973,191...114,041,127
Ensembl chr2B:232,849,239...232,852,967

NPY

neuropeptide Y

involved_in

(PMID:8837218)

PMID:8837218

NCBI chr 7:24,963,056...24,970,803
Ensembl chr 7:24,568,041...24,574,657

negative regulation of spontaneous neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PPP1R9A

protein phosphatase 1 regulatory subunit 9A

NCBI chr 7:86,863,919...87,251,634
Ensembl chr 7:100,455,357...100,833,220

PRKN

parkin RBR E3 ubiquitin protein ligase

involved_in

GO_REF:0000107

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

negative regulation of synaptic vesicle exocytosis

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BRAF

B-Raf proto-oncogene, serine/threonine kinase

acts_upstream_of_or_within

(MGI:5490391|PMID:23616533)

PMID:23616533

MGI:5490391

NCBI chr 7:132,651,908...132,855,422
Ensembl chr 7:145,138,510...145,327,115

FMR1

Fragile X messenger ribonucleoprotein 1

involved_in

PMID:24709664

NCBI chr X:136,937,889...136,976,828
Ensembl chr X:147,365,748...147,405,321

RAP1A

RAP1A, member of RAS oncogene family

acts_upstream_of_or_within

(MGI:5490391|PMID:23616533)

PMID:23616533

MGI:5490391

NCBI chr 1:114,279,255...114,376,977
Ensembl chr 1:125,971,598...125,994,813

RAP1B

RAP1B, member of RAS oncogene family

acts_upstream_of_or_within

(MGI:5490391|PMID:23616533)

PMID:23616533

MGI:5490391

NCBI chr12:66,122,212...66,172,450
Ensembl chr12:68,942,053...68,955,649

SYT4

synaptotagmin 4

involved_in

(MGI:4457852|PMID:19448629)

SynGO-UCL

PMID:19448629

MGI:4457852

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

negative regulation of testosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

IGFBP3

insulin like growth factor binding protein 3

NCBI chr 7:46,564,234...46,573,145

negative regulation of Wnt protein secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

OPRM1

opioid receptor mu 1

involved_in

GO_REF:0000107

NCBI chr 6:151,827,323...151,937,658
Ensembl chr 6:156,517,661...157,088,251

neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ASIC1

acid sensing ion channel subunit 1

acts_upstream_of
involved_in

(MGI:3841883|PMID:18094106)

PMID:18094106

GO_REF:0000107 MGI:3841883

NCBI chr12:38,672,253...38,698,247

BRSK1

BR serine/threonine kinase 1

involved_in

PMID:16630837

NCBI chr19:52,326,538...52,355,060
Ensembl chr19:61,021,493...61,045,659

CACNA1B

calcium voltage-gated channel subunit alpha1 B

acts_upstream_of_or_within

(MGI:3040168|PMID:12827191)

MGI:3040168

NCBI chr 9:108,989,621...109,256,841

DGKI

diacylglycerol kinase iota

acts_upstream_of_or_within
involved_in

(MGI:4936793|PMID:21119615)

PMID:21119615

GO_REF:0000107 MGI:4936793

NCBI chr 7:129,339,330...129,812,443
Ensembl chr 7:141,841,852...142,142,310

DVL1

dishevelled segment polarity protein 1

acts_upstream_of_or_within
involved_in

(MGI:3653273|PMID:16818724)

PMID:16818724

GO_REF:0000107 MGI:3653273

NCBI chr 1:92,469...106,748
Ensembl chr 1:1,292,052...1,301,008

LIN7A

lin-7 homolog A, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

(MGI:3607873|PMID:16186258)

Ensembl
MGI
UniProt

PMID:16186258

GO_REF:0000104 GO_REF:0000107 MGI:3607873

NCBI chr12:78,312,501...78,456,871
Ensembl chr12:81,442,152...81,567,522

LIN7B

lin-7 homolog B, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

(MGI:3607873|PMID:16186258)

Ensembl
MGI
UniProt

PMID:16186258

GO_REF:0000104 GO_REF:0000107 MGI:3607873

NCBI chr19:46,125,272...46,129,450
Ensembl chr19:55,047,704...55,055,761

LIN7C

lin-7 homolog C, crumbs cell polarity complex component

involved_in
acts_upstream_of_or_within

(MGI:3607873|PMID:16186258)

Ensembl
MGI
UniProt

PMID:16186258

GO_REF:0000104 GO_REF:0000107 MGI:3607873

NCBI chr11:27,458,735...27,471,068
Ensembl chr11:27,361,301...27,373,440

neurofibromin 1

acts_upstream_of
involved_in

(MGI:3612345|PMID:16298082)

PMID:16298082

GO_REF:0000107 MGI:3612345

NCBI chr17:25,425,081...25,703,689
Ensembl chr17:26,160,855...26,439,295

NRXN1

neurexin 1

acts_upstream_of_or_within

(MGI:3040168|PMID:12827191)

MGI:3040168

NCBI chr2A:50,063,398...51,178,659
Ensembl chr2A:50,985,067...52,091,277

NRXN2

neurexin 2

involved_in
acts_upstream_of_or_within

(MGI:3040168|PMID:12827191)

GO_REF:0000107 MGI:3040168

NCBI chr11:59,959,917...60,078,093
Ensembl chr11:63,303,659...63,409,687

NRXN3

neurexin 3

acts_upstream_of_or_within

(MGI:3040168|PMID:12827191)

MGI:3040168

NCBI chr14:58,729,335...60,444,769
Ensembl chr14:78,002,036...79,619,696

PPFIA3

PTPRF interacting protein alpha 3

NCBI chr19:46,130,396...46,162,065
Ensembl chr19:55,056,824...55,089,124

PPT1

palmitoyl-protein thioesterase 1

acts_upstream_of_or_within
involved_in

(MGI:3608104|PMID:16242638)

PMID:16242638

GO_REF:0000107 MGI:3608104

NCBI chr 1:39,358,424...39,383,087
Ensembl chr 1:40,683,841...40,708,609

PTPRN2

protein tyrosine phosphatase receptor type N2

involved_in

GO_REF:0000107

NCBI chr 7:149,158,513...150,390,077
Ensembl chr 7:160,851,703...161,756,325

RIMS1

regulating synaptic membrane exocytosis 1

acts_upstream_of_or_within

(MGI:5634213|PMID:25730884)

PMID:25730884

MGI:5634213

NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422

RIMS2

regulating synaptic membrane exocytosis 2

acts_upstream_of_or_within

(MGI:5634213|PMID:25730884)

PMID:25730884

MGI:5634213

NCBI chr 8:100,156,403...100,894,128

synaptosome associated protein 25

acts_upstream_of_or_within
involved_in

(MGI:2156357|PMID:11753414)

PMID:11753414

GO_REF:0000107 MGI:2156357

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SNAP91

synaptosome associated protein 91

involved_in

(MGI:4418638|PMID:11102472)

PMID:11102472

MGI:4418638

NCBI chr 6:81,441,792...81,600,505
Ensembl chr 6:84,720,850...84,874,407

SNCA

synuclein alpha

acts_upstream_of
involved_in

(MGI:3512696|PMID:15510220)

PMID:15510220

GO_REF:0000107 MGI:3512696

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

STXBP1

syntaxin binding protein 1

acts_upstream_of_or_within
involved_in

(MGI:3588009|PMID:15255974)

PMID:15255974

GO_REF:0000107 MGI:3588009

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

SYN1

synapsin I

acts_upstream_of_or_within

(MGI:74599|PMID:7777057)

PMID:7777057

MGI:74599

NCBI chr X:40,007,777...40,055,801

SYN2

synapsin II

acts_upstream_of_or_within
involved_in

(MGI:74599|PMID:7777057)

MGI
InterPro
Ensembl

PMID:7777057

GO_REF:0000002 GO_REF:0000107 MGI:74599

NCBI chr 3:11,935,680...12,118,981
Ensembl chr 3:12,282,573...12,464,413

SYN3

synapsin III

involved_in

InterPro

GO_REF:0000002

NCBI chr22:13,517,932...14,069,661
Ensembl chr22:31,373,604...31,866,798

synaptotagmin 1

acts_upstream_of_or_within
involved_in

(MGI:3047044|PMID:15197251)

PMID:15197251

GO_REF:0000107 MGI:3047044

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

SYT4

synaptotagmin 4

acts_upstream_of_or_within

(MGI:3047044|PMID:15197251)

PMID:15197251

MGI:3047044

NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721

UNC13A

unc-13 homolog A

acts_upstream_of

PMID:7559667 PMID:11792326

(MGI:2158119|PMID:11792326)

RGD
MGI

MGI:2158119 RGD:634400

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

WNT7A

Wnt family member 7A

acts_upstream_of_or_within
involved_in

(MGI:3653273|PMID:16818724)

PMID:16818724

GO_REF:0000107 MGI:3653273

NCBI chr 3:13,733,487...13,797,189
Ensembl chr 3:14,077,839...14,138,386

neurotransmitter secretion involved in regulation of skeletal muscle contraction

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NR4A1

nuclear receptor subfamily 4 group A member 1

NCBI chr12:36,703,903...36,740,211
Ensembl chr12:37,480,300...37,501,188

norepinephrine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

nischarin

NCBI chr 3:52,397,576...52,435,127
Ensembl chr 3:53,626,317...53,662,567

parathyroid hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

GATA3

GATA binding protein 3

acts_upstream_of_or_within
involved_in

(MGI:4460059|PMID:20484821)

PMID:20484821

GO_REF:0000107 MGI:4460059

NCBI chr10:8,075,951...8,105,573
Ensembl chr10:8,064,207...8,086,272

LOC100990398

transient receptor potential cation channel subfamily V member 6

acts_upstream_of_or_within
involved_in

(MGI:3777868|PMID:17129178)

PMID:17129178

GO_REF:0000107 MGI:3777868

NCBI chr 7:134,862,223...134,877,051
Ensembl chr 7:147,353,684...147,368,475

peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CPE

carboxypeptidase E

acts_upstream_of_or_within

(MGI:3607040|PMID:16219686)

PMID:16219686

MGI:3607040

NCBI chr 4:157,575,157...157,705,173
Ensembl chr 4:169,659,007...169,780,739

EDN1

endothelin 1

involved_in

GO_REF:0000107

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

EDN3

endothelin 3

involved_in

GO_REF:0000107

NCBI chr20:55,652,770...55,678,486
Ensembl chr20:57,012,926...57,038,570

EXOC3L1

exocyst complex component 3 like 1

involved_in

GO_REF:0000107

NCBI chr16:47,528,974...47,536,826
Ensembl chr16:66,918,261...66,924,223

HTT

huntingtin

acts_upstream_of_or_within

(MGI:1333401|PMID:10078572)
(MGI:2387270|PMID:12223581)

PMID:10078572 PMID:12223581

MGI:1333401 MGI:2387270

NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730

ILDR1

immunoglobulin like domain containing receptor 1

acts_upstream_of
involved_in

(MGI:5514075|PMID:23863714)

PMID:23863714

GO_REF:0000107 MGI:5514075

NCBI chr 3:119,088,855...119,124,831
Ensembl chr 3:125,996,018...126,032,041

SMPD3

sphingomyelin phosphodiesterase 3

acts_upstream_of_or_within
involved_in

(MGI:3575080|PMID:15764706)

PMID:15764706

GO_REF:0000107 MGI:3575080

NCBI chr16:48,734,664...48,825,241
Ensembl chr16:68,131,905...68,142,871

positive regulation of acetylcholine secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2A

adenosine A2a receptor

phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin

PMID:12679375

RGD:1625693

NCBI chr22:5,233,876...5,248,622
Ensembl chr22:22,104,253...22,114,189

HTR2C

5-hydroxytryptamine receptor 2C

NCBI chr X:103,673,172...103,999,133
Ensembl chr X:114,199,485...114,503,201

SLC18A3

solute carrier family 18 member A3

involved_in

(MGI:4366600|PMID:19635813)

PMID:19635813

MGI:4366600

NCBI chr10:44,630,006...44,632,419

TACR2

tachykinin receptor 2

NCBI chr10:65,872,795...65,885,154
Ensembl chr10:68,403,979...68,415,224

positive regulation of adiponectin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

C1QTNF3

C1q and TNF related 3

involved_in

(PMID:18421280)
(MGI:5442507|PMID:17299102)

PMID:17299102 PMID:18421280

MGI:5442507

NCBI chr 5:76,292,679...76,325,064
Ensembl chr 5:81,687,891...81,742,003

HCAR2

hydroxycarboxylic acid receptor 2

involved_in

PMID:19141678

NCBI chr12:120,305,297...120,308,463

PPARG

peroxisome proliferator activated receptor gamma

acts_upstream_of_or_within

PMID:29695452

NCBI chr 3:12,215,322...12,361,669
Ensembl chr 3:12,622,397...12,705,060

positive regulation of aldosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BMP6

bone morphogenetic protein 6

NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649

C1QTNF1

C1q and TNF related 1

involved_in

GO_REF:0000107

NCBI chr17:73,099,560...73,126,304
Ensembl chr17:78,644,531...78,669,386

DAB2

DAB adaptor protein 2

NCBI chr 5:70,951,198...71,004,836
Ensembl chr 5:76,022,143...76,041,443

positive regulation of androgen secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NKX3-1

NK3 homeobox 1

involved_in

GO_REF:0000107

NCBI chr 8:22,926,145...22,930,396
Ensembl chr 8:19,863,275...19,864,942

positive regulation of calcitonin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

PTGER4

prostaglandin E receptor 4

NCBI chr 5:69,686,906...69,700,739
Ensembl chr 5:74,731,470...74,745,148

positive regulation of calcium ion-dependent exocytosis of neurotransmitter

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

synaptotagmin 1

involved_in

GO_REF:0000107

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

positive regulation of corticosterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone

PMID:12606499 PMID:20663987

RGD:5508201 RGD:704397

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

ECRG4

ECRG4 augurin precursor

involved_in

(PMID:20233222)

PMID:20233222

NCBI chr2A:95,762,149...95,774,834
Ensembl chr2A:107,140,895...107,152,967

TAC1

tachykinin precursor 1

NCBI chr 7:89,675,834...89,684,391
Ensembl chr 7:103,257,501...103,266,389

positive regulation of corticotropin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apelin

NCBI chr X:118,775,509...118,785,224

corticotropin releasing hormone

involved_in

PMID:7477349 PMID:20663987

GO_REF:0000107 RGD:5508201 RGD:70047

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

ECRG4

ECRG4 augurin precursor

involved_in

(PMID:20233222)

PMID:20233222

NCBI chr2A:95,762,149...95,774,834
Ensembl chr2A:107,140,895...107,152,967

ghrelin and obestatin prepropeptide

involved_in

GO_REF:0000107

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

LIF

LIF interleukin 6 family cytokine

NCBI chr22:11,276,576...11,282,972
Ensembl chr22:29,078,862...29,095,608

PEX5L

peroxisomal biogenesis factor 5 like

NCBI chr 3:176,823,918...177,065,528
Ensembl chr 3:184,999,947...185,237,645

RAB8B

RAB8B, member RAS oncogene family

NCBI chr15:42,136,776...42,214,792
Ensembl chr15:60,432,749...60,510,547

UCN

urocortin

involved_in

PMID:7477349

GO_REF:0000107 RGD:70047

NCBI chr2A:27,309,458...27,311,268
Ensembl chr2A:27,397,295...27,397,669

positive regulation of corticotropin-releasing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

apelin

NCBI chr X:118,775,509...118,785,224

ECRG4

ECRG4 augurin precursor

involved_in

(PMID:20233222)

PMID:20233222

NCBI chr2A:95,762,149...95,774,834
Ensembl chr2A:107,140,895...107,152,967

TNFSF11

TNF superfamily member 11

involved_in

GO_REF:0000107

NCBI chr13:23,750,835...23,784,740

positive regulation of cortisol secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone

involved_in

GO_REF:0000107

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

GAL

galanin and GMAP prepropeptide

involved_in

GO_REF:0000107

NCBI chr11:63,770,758...63,777,421
Ensembl chr11:67,075,547...67,081,696

GALR1

galanin receptor 1

involved_in

GO_REF:0000107

NCBI chr18:70,643,718...70,664,068
Ensembl chr18:73,899,995...73,917,752

ghrelin and obestatin prepropeptide

involved_in

GO_REF:0000107

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

positive regulation of dopamine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CHRNB2

cholinergic receptor nicotinic beta 2 subunit

acts_upstream_of_or_within

(MGI:1194464|PMID:9428762)

PMID:9428762

MGI:1194464

NCBI chr 1:129,922,740...129,931,582
Ensembl chr 1:133,535,023...133,547,361

CXCL12

C-X-C motif chemokine ligand 12

NCBI chr10:41,296,975...41,384,864
Ensembl chr10:44,552,480...44,564,231

HTR6

5-hydroxytryptamine receptor 6

NCBI chr 1:18,619,683...18,635,822
Ensembl chr 1:19,662,978...19,678,680

NPY2R

neuropeptide Y receptor Y2

NCBI chr 4:147,542,551...147,586,397
Ensembl chr 4:159,401,080...159,402,231

OPRK1

opioid receptor kappa 1

NCBI chr 8:49,650,844...49,677,494
Ensembl chr 8:47,029,313...47,056,577

PCP4

Purkinje cell protein 4

NCBI chr21:26,069,039...26,284,247
Ensembl chr21:39,587,400...39,618,734

PINK1

PTEN induced kinase 1

acts_upstream_of_or_within
involved_in

(MGI:3715376|PMID:17563363)

PMID:17563363

GO_REF:0000107 MGI:3715376

NCBI chr 1:19,583,330...19,601,248
Ensembl chr 1:20,627,693...20,645,560

reticulon 4

NCBI chr2A:55,129,272...55,207,031

SLC18A1

solute carrier family 18 member A1

NCBI chr 8:19,369,843...19,408,412
Ensembl chr 8:16,318,744...16,353,708

synaptotagmin 1

involved_in

PMID:28370453

NCBI chr12:76,392,955...76,981,800
Ensembl chr12:79,595,704...79,829,923

positive regulation of estradiol secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP19A1

cytochrome P450 family 19 subfamily A member 1

involved_in

GO_REF:0000107

NCBI chr15:30,152,924...30,282,854
Ensembl chr15:48,486,688...48,521,554

IL6

interleukin 6

involved_in

(PMID:24139936)

PMID:24139936

NCBI chr 7:23,415,922...23,420,767

mitofusin 2

NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077

SPP1

secreted phosphoprotein 1

involved_in

GO_REF:0000107

NCBI chr 4:80,263,711...80,271,466
Ensembl chr 4:90,988,200...90,995,935

TNF

tumor necrosis factor

involved_in

(PMID:24139936)

PMID:24139936

NCBI chr 6:31,236,650...31,239,423
Ensembl chr 6:32,126,618...32,129,381

positive regulation of fever generation by positive regulation of prostaglandin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

TNFRSF11A

TNF receptor superfamily member 11a

involved_in

GO_REF:0000107

NCBI chr18:55,695,394...55,761,307
Ensembl chr18:59,034,770...59,075,044

TNFSF11

TNF superfamily member 11

involved_in

GO_REF:0000107

NCBI chr13:23,750,835...23,784,740

positive regulation of follicle-stimulating hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ACVR2A

activin A receptor type 2A

NCBI chr2B:11,933,683...12,020,287
Ensembl chr2B:152,253,826...152,288,385

FOXL2

forkhead box L2

acts_upstream_of_or_within

(MGI:5604269|PMID:24739304)

MGI:5604269

NCBI chr 3:135,968,040...135,980,063

INHBB

inhibin subunit beta B

involved_in

(PMID:3122219)

PMID:3122219

NCBI chr2B:7,278,944...7,284,632

leptin

NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519

SMAD4

SMAD family member 4

acts_upstream_of_or_within
involved_in

(MGI:5604269|PMID:24739304)

GO_REF:0000107 MGI:5604269

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

positive regulation of glucagon secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

free fatty acid receptor 4

involved_in

GO_REF:0000107

NCBI chr10:90,312,647...90,336,115
Ensembl chr10:93,823,004...93,860,262

positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

DTNBP1

dystrobrevin binding protein 1

NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256

RAB3GAP1

RAB3 GTPase activating protein catalytic subunit 1

involved_in

(MGI:3652690|PMID:16782817)

ParkinsonsUK-UCL

PMID:16782817

MGI:3652690

NCBI chr2B:24,692,363...24,810,685
Ensembl chr2B:139,125,375...139,242,721

positive regulation of glutamate secretion, neurotransmission

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

KMO

kynurenine 3-monooxygenase

NCBI chr 1:217,094,037...217,157,827
Ensembl chr 1:222,075,268...222,138,866

STXBP1

syntaxin binding protein 1

NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152

positive regulation of growth hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCYAP1

adenylate cyclase activating polypeptide 1

NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749

ARHGEF7

Rho guanine nucleotide exchange factor 7

acts_upstream_of_or_within
involved_in

(MGI:5314863|PMID:21828338)

PMID:21828338

GO_REF:0000107 MGI:5314863

NCBI chr13:92,246,107...92,436,173
Ensembl chr13:111,427,905...111,545,413

DRD2

dopamine receptor D2

acts_upstream_of_or_within
involved_in

(MGI:3619650|PMID:11897683)

PMID:11897683

GO_REF:0000107 MGI:3619650

NCBI chr11:108,289,838...108,357,174
Ensembl chr11:112,132,703...112,198,935

GABBR1

gamma-aminobutyric acid type B receptor subunit 1

NCBI chr 6:29,405,026...29,437,108
Ensembl chr 6:30,065,119...30,095,304

growth hormone releasing hormone

involved_in
acts_upstream_of_or_within

PMID:3008329 PMID:6130528 PMID:10579333

(PMID:3008329)

RGD
Ensembl
MGI

GO_REF:0000107 RGD:1624957 RGD:5687318

NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240

growth hormone releasing hormone receptor

involved_in
acts_upstream_of_or_within

PMID:978118 PMID:3008329 PMID:6303755 PMID:23825127

(MGI:54187|PMID:978118), (MGI:55531|PMID:6303755), (MGI:56721|PMID:3008329)

RGD
Ensembl
MGI

GO_REF:0000107 MGI:54187 MGI:55531 MGI:56721 RGD:10401239

NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200

ghrelin and obestatin prepropeptide

involved_in

GO_REF:0000107

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

intersectin 1

NCBI chr21:20,009,385...20,266,835
Ensembl chr21:33,457,081...33,625,248

KISS1

KiSS-1 metastasis suppressor

NCBI chr 1:179,792,116...179,800,377
Ensembl chr 1:184,080,570...184,104,815

O-GlcNAcase

NCBI chr10:98,387,144...98,421,105
Ensembl chr10:101,858,879...101,892,479

SELENOT

selenoprotein T

involved_in

PMID:18198219

NCBI chr 3:147,620,862...147,648,039
Ensembl chr 3:155,194,428...155,221,578

SERP1

stress associated endoplasmic reticulum protein 1

acts_upstream_of_or_within
involved_in

(MGI:3619104|PMID:16415102)

PMID:16415102

GO_REF:0000107 MGI:3619104

NCBI chr 3:147,559,607...147,564,668
Ensembl chr 3:155,133,115...155,137,241

positive regulation of histamine secretion by mast cell

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

NPPA

natriuretic peptide A

involved_in

PMID:9663691

NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373

PLA2G3

phospholipase A2 group III

involved_in

GO_REF:0000107

NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160

SNX4

sorting nexin 4

involved_in

GO_REF:0000107

NCBI chr 3:122,578,527...122,652,007
Ensembl chr 3:129,443,369...129,515,917

VAMP7

vesicle associated membrane protein 7

involved_in

(PMID:18253931)

PMID:18253931

NCBI chr X:145,362,432...145,425,097
Ensembl chr X:155,257,185...155,320,215

VAMP8

vesicle associated membrane protein 8

involved_in

GO_REF:0000107

NCBI chr2A:85,627,678...85,632,205
Ensembl chr2A:87,180,681...87,185,195

positive regulation of hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CNTF

ciliary neurotrophic factor

Fgf2 release from spinal cord astrocytes

PMID:11771938

RGD:1626172

NCBI chr11:53,876,081...53,882,870
Ensembl chr11:57,336,792...57,341,121

CREB1

cAMP responsive element binding protein 1

involved_in
acts_upstream_of_or_within

(MGI:3611103|PMID:16141355)

PMID:16141355

GO_REF:0000107 MGI:3611103

NCBI chr2B:94,762,796...94,836,304
Ensembl chr2B:212,891,261...212,958,130

EDN1

endothelin 1

involved_in

GO_REF:0000107

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

endothelin 2

NCBI chr 1:40,777,582...40,783,410
Ensembl chr 1:42,092,811...42,098,721

EDN3

endothelin 3

involved_in

GO_REF:0000107

NCBI chr20:55,652,770...55,678,486
Ensembl chr20:57,012,926...57,038,570

growth hormone releasing hormone

acts_upstream_of_or_within
involved_in

(MGI:3607618|PMID:15985453), (MGI:3695097|PMID:16246898)
(MGI:1098976|PMID:9348175)

PMID:9348175 PMID:15985453 PMID:16246898

GO_REF:0000107 MGI:1098976 MGI:3607618 MGI:3695097

NCBI chr20:33,573,001...33,583,699
Ensembl chr20:34,687,587...34,693,240

growth hormone releasing hormone receptor

acts_upstream_of_or_within
involved_in

(MGI:52244|PMID:7679139)

PMID:7679139

GO_REF:0000107 MGI:52244

NCBI chr 7:31,582,134...31,592,914
Ensembl chr 7:31,696,914...31,712,200

KISS1 receptor

NCBI chr19:211,563...215,332

NELL2

neural EGFL like 2

involved_in

PMID:18547942

NCBI chr12:43,820,215...44,226,249
Ensembl chr12:44,688,209...45,094,070

NMB

neuromedin B

thyrotropin (TSH); pituitary gland of hyperthyroid rats with or without addition of thyroxin (T4)

PMID:8136736

RGD:1642348

NCBI chr15:63,322,869...63,326,989

neuromedin U

NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965

P2RY1

purinergic receptor P2Y1

NCBI chr 3:149,859,748...149,865,873
Ensembl chr 3:157,426,692...157,427,813

protein tyrosine phosphatase non-receptor type 11

acts_upstream_of_or_within

(MGI:3513751|PMID:15520383)

NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762

synaptosome associated protein 25

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SOX11

SRY-box transcription factor 11

involved_in

(MGI:5285123|PMID:21527504)

PMID:21527504

MGI:5285123

NCBI chr2A:5,699,738...5,711,210

TACR1

tachykinin receptor 1

NCBI chr2A:75,111,339...75,267,320
Ensembl chr2A:76,614,478...76,771,018

positive regulation of insulin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

AACS

acetoacetyl-CoA synthetase

NCBI chr12:122,660,621...122,737,421
Ensembl chr12:126,942,340...127,019,372

ABAT

4-aminobutyrate aminotransferase

NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420

ACSL4

acyl-CoA synthetase long chain family member 4

involved_in

PMID:23766516

NCBI chr X:98,731,109...98,841,067
Ensembl chr X:109,206,964...109,310,914

ADCY8

adenylate cyclase 8

involved_in

GO_REF:0000107

NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073

ANXA7

annexin A7

acts_upstream_of_or_within_positive_effect

(MGI:1349234|PMID:10570150)

PMID:10570150

MGI:1349234

NCBI chr10:69,923,353...69,962,980
Ensembl chr10:72,381,447...72,420,749

BAD

BCL2 associated agonist of cell death

involved_in

GO_REF:0000107

NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257

BLK

BLK proto-oncogene, Src family tyrosine kinase

involved_in

GO_REF:0000107

NCBI chr 8:7,637,680...7,708,914

CACNA1C

calcium voltage-gated channel subunit alpha1 C

NCBI chr12:2,166,672...2,817,827
Ensembl chr12:2,114,140...2,744,826

CAPN10

calpain 10

involved_in

GO_REF:0000107

NCBI chr2B:127,838,477...127,851,334
Ensembl chr2B:246,645,630...246,679,169

CASK

calcium/calmodulin dependent serine protein kinase

NCBI chr X:33,967,329...34,374,385
Ensembl chr X:41,659,295...42,066,570

CASR

calcium sensing receptor

NCBI chr 3:119,278,071...119,383,901
Ensembl chr 3:126,252,765...126,285,268

CD38 molecule

NCBI chr 4:10,228,803...10,295,129
Ensembl chr 4:15,525,835...15,587,677

CHRM3

cholinergic receptor muscarinic 3

involved_in

(MGI:3769934|PMID:16753580)
(MGI:4459350|PMID:20440069)

PMID:16753580 PMID:20440069

MGI:3769934 MGI:4459350

NCBI chr 1:214,931,514...215,452,739

DOC2B

double C2 domain beta

involved_in

(MGI:4457249|PMID:17548353)

PMID:17548353

MGI:4457249

NCBI chr17:19,854...58,336

coagulation factor II, thrombin

involved_in

GO_REF:0000107

NCBI chr11:46,669,925...46,690,391
Ensembl chr11:47,227,891...47,249,157

F2RL2

coagulation factor II thrombin receptor like 2

involved_in

GO_REF:0000107

NCBI chr 5:38,680,372...38,688,509
Ensembl chr 5:39,297,424...39,305,370

FFAR1

free fatty acid receptor 1

involved_in

PMID:16081037

GO_REF:0000107 RGD:2315053

NCBI chr19:32,298,259...32,300,601
Ensembl chr19:41,034,905...41,035,807

FFAR2

free fatty acid receptor 2

involved_in

GO_REF:0000107

NCBI chr19:32,394,401...32,398,730
Ensembl chr19:41,132,599...41,133,591

GCK

glucokinase

involved_in
acts_upstream_of_or_within

PMID:7556622 PMID:17028192 PMID:17360975

in response to glucose stimulation
(MGI:76949|PMID:7556622)

RGD
Ensembl
MGI

GO_REF:0000107 MGI:76949 RGD:1581879 RGD:2301916

NCBI chr 7:44,857,604...44,903,683
Ensembl chr 7:44,926,848...44,937,751

ghrelin and obestatin prepropeptide

involved_in

GO_REF:0000104

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

GIP

gastric inhibitory polypeptide

involved_in

PMID:8958204 PMID:9075801 PMID:20138041 PMID:33196462

(MGI:7336811|PMID:9075801), (MGI:7343841|PMID:20138041)
(MGI:6780326|PMID:33196462)

RGD
MGI

MGI:6780326 MGI:7336811 MGI:7343841 RGD:2312537

NCBI chr17:8,573,104...8,580,424

GIPR

gastric inhibitory polypeptide receptor

involved_in

PMID:11014226

GO_REF:0000107 RGD:2312607

NCBI chr19:42,673,553...42,688,059
Ensembl chr19:51,213,090...51,225,293

GJA1

gap junction protein alpha 1

NCBI chr 6:119,213,513...119,227,617

GLP1R

glucagon like peptide 1 receptor

NCBI chr 6:38,637,838...38,680,423
Ensembl chr 6:39,823,373...39,855,784

glutaredoxin

NCBI chr 5:19,526,210...19,535,237
Ensembl chr 5:19,671,965...19,680,685

GLUD1

glutamate dehydrogenase 1

involved_in
acts_upstream_of_or_within

PMID:11502802 PMID:16959573

(PMID:11502802)
(MGI:3769241|PMID:16959573)

BHF-UCL
MGI

MGI:3769241

NCBI chr10:83,498,338...83,540,730

GLUL

glutamate-ammonia ligase

ornithine alpha-ketoglutarate-induced secretion

PMID:12575909

RGD:2301557

NCBI chr 1:157,882,258...157,891,562
Ensembl chr 1:161,534,106...161,543,411

GNA11

G protein subunit alpha 11

involved_in

(MGI:4459350|PMID:20440069)
(MGI:5780510|PMID:26075576)

PMID:20440069 PMID:26075576

MGI:4459350 MGI:5780510

NCBI chr19:2,120,398...2,149,161
Ensembl chr19:3,074,483...3,102,124

GNAQ

G protein subunit alpha q

involved_in

(MGI:4459350|PMID:20440069)
(MGI:5780510|PMID:26075576)

PMID:20440069 PMID:26075576

MGI:4459350 MGI:5780510

NCBI chr 9:46,816,409...47,129,116
Ensembl chr 9:76,575,815...76,773,849

G protein-coupled receptor 39

acts_upstream_of_or_within

(MGI:4355293|PMID:19213841)

PMID:19213841

MGI:4355293

NCBI chr2B:27,429,851...27,431,292

GPR68

G protein-coupled receptor 68

acts_upstream_of_or_within
involved_in

(MGI:5444590|PMID:22733973)

PMID:22733973

GO_REF:0000107 MGI:5444590

NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806

HNF1 homeobox A

NCBI chr12:118,562,308...118,584,596
Ensembl chr12:121,932,671...121,955,911

IRS2

insulin receptor substrate 2

involved_in

(MGI:4456946|PMID:15572028)

PMID:15572028

MGI:4456946

NCBI chr13:90,886,095...90,917,724

ISL1

ISL LIM homeobox 1

involved_in

PMID:11978636

GO_REF:0000107 RGD:729103

NCBI chr 5:62,635,095...62,650,141
Ensembl chr 5:64,252,715...64,264,674

ITPR1

inositol 1,4,5-trisphosphate receptor type 1

involved_in

GO_REF:0000107

NCBI chr 3:4,448,574...4,802,545
Ensembl chr 3:4,572,921...4,904,811

JAK2

Janus kinase 2

in response to human growth hormone

PMID:16597920

RGD:1641815

NCBI chr 9:4,820,303...4,971,867
Ensembl chr 9:5,006,271...5,156,626

LOC100967334

G-protein coupled estrogen receptor 1

involved_in

(MGI:5141337|PMID:21673097)

PMID:21673097

MGI:5141337

NCBI chr 7:1,245,873...1,251,915

LOC100978090

protein ALEX

involved_in

GO_REF:0000107

NCBI chr20:55,204,188...55,206,608
Ensembl chr20:56,474,459...56,621,747

LOC100990650

guanine nucleotide-binding protein G(s) subunit alpha

involved_in

(MGI:3773405|PMID:17971513)
(MGI:6759698|PMID:34091063)
(MGI:6780326|PMID:33196462)

PMID:17971513 PMID:33196462 PMID:34091063

MGI:3773405 MGI:6759698 MGI:6780326

NCBI chr20:55,190,607...55,262,245

LRRC8A

leucine rich repeat containing 8 VRAC subunit A

involved_in

GO_REF:0000107

NCBI chr 9:100,003,969...100,039,859
Ensembl chr 9:128,670,292...128,705,466

MCU

mitochondrial calcium uniporter

involved_in

GO_REF:0000107

NCBI chr10:69,243,282...69,435,193
Ensembl chr10:71,845,335...71,898,545

MYRIP

myosin VIIA and Rab interacting protein

involved_in

PMID:17827149

NCBI chr 3:39,715,890...40,163,826
Ensembl chr 3:40,079,777...40,433,613

NK6 homeobox 1

NCBI chr 4:39,683,420...39,689,651

NLGN2

neuroligin 2

involved_in

PMID:18755801 PMID:22528485

(PMID:22528485)

RGD
CACAO

RGD:2314456 RGD:9743981

NCBI chr17:7,438,853...7,454,014

NNAT

neuronatin

acts_upstream_of_or_within

(MGI:3614320|PMID:15793245)

PMID:15793245

MGI:3614320

NCBI chr20:33,842,071...33,845,575
Ensembl chr20:34,955,234...34,959,493

NR0B2

nuclear receptor subfamily 0 group B member 2

NCBI chr 1:26,174,055...26,176,689
Ensembl chr 1:27,230,362...27,232,942

O-GlcNAcase

NCBI chr10:98,387,144...98,421,105
Ensembl chr10:101,858,879...101,892,479

ORAI1

ORAI calcium release-activated calcium modulator 1

involved_in

(MGI:6389409|PMID:31664108)

PMID:31664108

MGI:6389409

NCBI chr12:119,229,069...119,243,435

PCK2

phosphoenolpyruvate carboxykinase 2, mitochondrial

NCBI chr14:4,872,276...4,882,118
Ensembl chr14:22,996,813...23,006,775

PDX1

pancreatic and duodenal homeobox 1

involved_in

ISO
ISS

RGD
UniProt

PMID:18439098

GO_REF:0000024 RGD:2306975

NCBI chr13:9,199,572...9,206,202

PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

NCBI chr 1:182,655,487...182,683,881
Ensembl chr 1:186,934,446...186,961,995

PFKM

phosphofructokinase, muscle

acts_upstream_of_or_within
involved_in

(MGI:3759009|PMID:17595219)

PMID:17595219

GO_REF:0000107 MGI:3759009

NCBI chr12:40,584,321...40,625,245
Ensembl chr12:41,459,346...41,499,476

PLCB1

phospholipase C beta 1

involved_in

GO_REF:0000107

NCBI chr20:8,106,665...8,858,572
Ensembl chr20:7,887,960...8,636,019

PRKACA

protein kinase cAMP-activated catalytic subunit alpha

involved_in

GO_REF:0000107

NCBI chr19:13,657,344...13,683,864
Ensembl chr19:14,385,191...14,406,205

PRKAR1A

protein kinase cAMP-dependent type I regulatory subunit alpha

involved_in

GO_REF:0000107

NCBI chr17:62,448,718...62,488,493
Ensembl chr17:67,838,484...67,877,943

PRKCB

protein kinase C beta

involved_in

GO_REF:0000107

NCBI chr16:13,888,936...14,268,759
Ensembl chr16:24,091,289...24,466,203

PRKCE

protein kinase C epsilon

acts_upstream_of_or_within
involved_in

(MGI:2675178|PMID:12837755)

PMID:12837755

GO_REF:0000107 MGI:2675178

NCBI chr2A:45,757,629...46,294,064
Ensembl chr2A:46,688,436...47,220,313

PSMD9

proteasome 26S subunit, non-ATPase 9

involved_in

PMID:10567574

NCBI chr12:119,490,380...119,519,318
Ensembl chr12:122,859,940...122,887,703

PTBP1

polypyrimidine tract binding protein 1

NCBI chr19:319,953...334,945

RAPGEF4

Rap guanine nucleotide exchange factor 4

involved_in

GO_REF:0000107

NCBI chr2B:60,022,738...60,339,981
Ensembl chr2B:177,655,733...177,793,644

RBP4

retinol binding protein 4

involved_in

GO_REF:0000107

NCBI chr10:90,337,879...90,347,530
Ensembl chr10:93,848,166...93,857,887

RPH3AL

rabphilin 3A like (without C2 domains)

involved_in

GO_REF:0000107

NCBI chr17:90,816...293,651
Ensembl chr17:146,155...283,278

SERP1

stress associated endoplasmic reticulum protein 1

acts_upstream_of_or_within
involved_in

(MGI:3619104|PMID:16415102)

PMID:16415102

GO_REF:0000107 MGI:3619104

NCBI chr 3:147,559,607...147,564,668
Ensembl chr 3:155,133,115...155,137,241

sirtuin 3

NCBI chr11:210,052...233,969
Ensembl chr11:255,191...278,732

SIRT6

sirtuin 6

involved_in

(MGI:6101624|PMID:27457971)

PMID:27457971

MGI:6101624

NCBI chr19:3,196,092...3,204,602
Ensembl chr19:4,146,057...4,154,126

SLC30A8

solute carrier family 30 member 8

involved_in

PMID:19479076

NCBI chr 8:113,624,785...113,851,633
Ensembl chr 8:116,223,595...116,394,095

synaptosome associated protein 25

NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841

SOX4

SRY-box transcription factor 4

involved_in

(MGI:3819280|PMID:18477811)

PMID:18477811

MGI:3819280

NCBI chr 6:21,422,846...21,427,779

STIM1

stromal interaction molecule 1

involved_in

(MGI:6389409|PMID:31664108)
(MGI:7335147|PMID:18452988)
(MGI:6206853|PMID:30131394), (MGI:6389409|PMID:31664108)

PMID:18452988 PMID:30131394 PMID:31664108

MGI:6206853 MGI:6389409 MGI:7335147

NCBI chr11:3,726,501...3,954,951
Ensembl chr11:3,840,513...4,065,224

TARDBP

TAR DNA binding protein

NCBI chr 1:9,775,084...9,786,710
Ensembl chr 1:10,996,006...11,008,732

TCF7L2

transcription factor 7 like 2

involved_in

GO_REF:0000107

NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281

TM7SF3

transmembrane 7 superfamily member 3

involved_in

GO_REF:0000107

NCBI chr12:59,298,725...59,340,896
Ensembl chr12:61,913,370...61,955,540

TRH

thyrotropin releasing hormone

NCBI chr 3:127,037,069...127,041,299
Ensembl chr 3:134,383,016...134,387,736

TRPM2

transient receptor potential cation channel subfamily M member 2

NCBI chr21:30,606,825...30,737,313
Ensembl chr21:43,903,811...44,035,298

urocortin 3

NCBI chr10:5,410,501...5,419,650
Ensembl chr10:5,405,683...5,406,168

positive regulation of insulin secretion involved in cellular response to glucose stimulus

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABCC8

ATP binding cassette subfamily C member 8

involved_in

(MGI:3831492|PMID:16924481)

PMID:16924481

MGI:3831492

NCBI chr11:17,447,564...17,531,513
Ensembl chr11:17,133,063...17,216,870

ABCG1

ATP binding cassette subfamily G member 1

NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050

ADCY8

adenylate cyclase 8

involved_in

GO_REF:0000107

NCBI chr 8:127,418,407...127,681,217
Ensembl chr 8:130,398,288...130,661,073

ANO1

anoctamin 1

involved_in

GO_REF:0000107

NCBI chr11:65,064,415...65,287,160
Ensembl chr11:68,473,555...68,576,451

ARRB1

arrestin beta 1

involved_in

(MGI:4453294|PMID:19915011)

PMID:19915011

MGI:4453294

NCBI chr11:70,319,935...70,411,276
Ensembl chr11:73,630,276...73,654,155

ATG7

autophagy related 7

acts_upstream_of_or_within

(MGI:5544155|PMID:24105478)

PMID:24105478

MGI:5544155

NCBI chr 3:11,208,600...11,488,757
Ensembl chr 3:11,554,100...11,833,398

BAD

BCL2 associated agonist of cell death

involved_in

GO_REF:0000107

NCBI chr11:59,626,981...59,641,824
Ensembl chr11:62,971,808...62,986,257

BAIAP3

BAI1 associated protein 3

involved_in

GO_REF:0000107

Ensembl chr16:1,390,160...1,403,978

C2CD2L

C2CD2 like

acts_upstream_of_or_within
involved_in

(MGI:5522601|PMID:24012759)

PMID:24012759

GO_REF:0000107 MGI:5522601

NCBI chr11:113,944,939...113,955,296
Ensembl chr11:117,875,077...117,883,581

CACNA1D

calcium voltage-gated channel subunit alpha1 D

NCBI chr 3:53,432,189...53,751,347
Ensembl chr 3:54,495,952...54,970,444

CAMK2N1

calcium/calmodulin dependent protein kinase II inhibitor 1

NCBI chr 1:19,437,761...19,441,573
Ensembl chr 1:20,479,562...20,482,600

CFTR

CF transmembrane conductance regulator

involved_in

GO_REF:0000107

NCBI chr 7:109,449,847...109,633,023
Ensembl chr 7:122,129,798...122,327,864

corticotropin releasing hormone

NCBI chr 8:62,714,721...62,716,979
Ensembl chr 8:64,383,419...64,384,009

DYNLL1

dynein light chain LC8-type 1

NCBI chr12:118,078,401...118,080,822
Ensembl chr12:121,452,118...121,454,550

GCG

glucagon

involved_in

GO_REF:0000107

NCBI chr2B:49,436,379...49,446,559
Ensembl chr2B:166,806,016...166,811,155

ghrelin and obestatin prepropeptide

NCBI chr 3:10,221,829...10,229,229
Ensembl chr 3:10,573,537...10,580,723

GPLD1

glycosylphosphatidylinositol specific phospholipase D1

involved_in

(MGI:5448527|PMID:20153004)

PMID:20153004

MGI:5448527

NCBI chr 6:24,257,923...24,332,171
Ensembl chr 6:24,588,672...24,665,229

GPR27

G protein-coupled receptor 27

acts_upstream_of_or_within

(MGI:5311513|PMID:22253604)

PMID:22253604

MGI:5311513

NCBI chr 3:71,693,611...71,696,247

G protein-coupled receptor 39

acts_upstream_of_or_within

(MGI:4437975|PMID:19213833)

PMID:19213833

MGI:4437975

NCBI chr2B:27,429,851...27,431,292

GPR68

G protein-coupled receptor 68

acts_upstream_of_or_within
involved_in

(MGI:5444590|PMID:22733973)

PMID:22733973

GO_REF:0000107 MGI:5444590

NCBI chr14:71,859,025...71,891,126
Ensembl chr14:91,207,679...91,208,806

HCFC1

host cell factor C1

involved_in

PMID:24250814

NCBI chr X:143,502,159...143,526,418
Ensembl chr X:153,389,859...153,412,999

HIF1A

hypoxia inducible factor 1 subunit alpha

acts_upstream_of_or_within
involved_in

(MGI:4459348|PMID:20440072)

PMID:20440072

GO_REF:0000107 MGI:4459348

NCBI chr14:42,295,691...42,348,478
Ensembl chr14:60,552,374...60,604,885

KIF5B

kinesin family member 5B

NCBI chr10:32,138,964...32,186,448
Ensembl chr10:32,731,150...32,778,242

leptin receptor

NCBI chr 1:64,772,612...64,881,886
Ensembl chr 1:66,693,926...66,764,768

LRP1

LDL receptor related protein 1

NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979

MPC2

mitochondrial pyruvate carrier 2

acts_upstream_of_or_within
involved_in

(MGI:5576400|PMID:24910426)

PMID:24910426

GO_REF:0000107 MGI:5576400

NCBI chr 1:143,406,611...143,424,508
Ensembl chr 1:147,132,213...147,151,648

myosin heavy chain 9

NCBI chr22:17,200,623...17,305,826
Ensembl chr22:35,039,101...35,121,618

NAD kinase

NCBI chr 1:462,860...485,203
Ensembl chr 1:1,619,270...1,642,269

NCOA6

nuclear receptor coactivator 6

NCBI chr20:31,044,339...31,154,798
Ensembl chr20:32,170,583...32,247,167

NR1H4

nuclear receptor subfamily 1 group H member 4

involved_in

GO_REF:0000107

NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058

OSBP

oxysterol binding protein

NCBI chr11:54,800,756...54,841,191
Ensembl chr11:58,252,925...58,291,154

OXCT1

3-oxoacid CoA-transferase 1

NCBI chr 5:68,528,765...68,668,305
Ensembl chr 5:73,563,758...73,710,316

PDX1

pancreatic and duodenal homeobox 1

acts_upstream_of_or_within

(MGI:5311513|PMID:22253604)

PMID:22253604

MGI:5311513

NCBI chr13:9,199,572...9,206,202

PLA2G6

phospholipase A2 group VI

involved_in

PMID:11278673

GO_REF:0000107 RGD:6482760

NCBI chr22:18,998,060...19,094,507
Ensembl chr22:36,849,794...36,919,509
Ensembl chr22:36,849,794...36,919,509

PPARD

peroxisome proliferator activated receptor delta

NCBI chr 6:34,903,798...34,987,208
Ensembl chr 6:36,003,988...36,081,132

PPP3CB

protein phosphatase 3 catalytic subunit beta

involved_in

GO_REF:0000107

NCBI chr10:69,984,241...70,043,352
Ensembl chr10:72,443,051...72,501,752

PRKN

parkin RBR E3 ubiquitin protein ligase

NCBI chr 6:159,293,016...160,679,106
Ensembl chr 6:164,314,990...165,678,770

RAC1

Rac family small GTPase 1

involved_in

(MGI:5489045|PMID:23412604)

RGD
CACAO

PMID:23412604

MGI:5489045 RGD:14392803

NCBI chr 7:7,039,379...7,068,866

RFX6

regulatory factor X6

involved_in

GO_REF:0000107

NCBI chr 6:114,686,132...114,741,072
Ensembl chr 6:118,828,973...118,883,884

sirtuin 1

NCBI chr10:64,368,878...64,401,684
Ensembl chr10:66,681,598...66,715,069

SLC2A2

solute carrier family 2 member 2

involved_in

GO_REF:0000107

NCBI chr 3:168,002,609...168,033,237
Ensembl chr 3:176,188,184...176,218,722

SRI

sorcin

involved_in

GO_REF:0000107

NCBI chr 7:80,199,719...80,214,733
Ensembl chr 7:93,850,496...93,864,029

STX4

syntaxin 4

involved_in

GO_REF:0000107

NCBI chr16:23,917,576...23,933,884
Ensembl chr16:31,400,915...31,411,364

syntabulin

NCBI chr 8:106,223,046...106,340,418
Ensembl chr 8:108,368,117...108,483,927

TRPA1

transient receptor potential cation channel subfamily A member 1

NCBI chr 8:68,551,685...68,605,336
Ensembl chr 8:70,210,352...70,262,627

TRPM4

transient receptor potential cation channel subfamily M member 4

NCBI chr19:46,168,301...46,224,726
Ensembl chr19:55,095,029...55,150,464

VSNL1

visinin like 1

acts_upstream_of_or_within
involved_in

(MGI:3694336|PMID:16731532)

PMID:16731532

GO_REF:0000107 MGI:3694336

NCBI chr2A:17,525,561...17,641,277
Ensembl chr2A:17,703,086...17,767,274

positive regulation of luteinizing hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FOXL2

forkhead box L2

acts_upstream_of_or_within

(MGI:5604269|PMID:24739304)

MGI:5604269

NCBI chr 3:135,968,040...135,980,063

KISS1

KiSS-1 metastasis suppressor

PMID:17213691 PMID:17532794

RGD:2292143 RGD:2292159

NCBI chr 1:179,792,116...179,800,377
Ensembl chr 1:184,080,570...184,104,815

leptin

NCBI chr 7:120,230,896...120,248,602
Ensembl chr 7:132,885,011...132,901,519

SMAD4

SMAD family member 4

acts_upstream_of_or_within
involved_in

(MGI:5604269|PMID:24739304)

GO_REF:0000107 MGI:5604269

NCBI chr18:44,402,112...44,456,779
Ensembl chr18:47,764,568...47,797,359

positive regulation of neurotransmitter secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

BAIAP3

BAI1 associated protein 3

involved_in

GO_REF:0000107

Ensembl chr16:1,390,160...1,403,978

CACNA1B

calcium voltage-gated channel subunit alpha1 B

NCBI chr 9:108,989,621...109,256,841

DTNBP1

dystrobrevin binding protein 1

involved_in

GO_REF:0000107

NCBI chr 6:15,377,263...15,523,317
Ensembl chr 6:15,741,698...15,887,256

SNCA

synuclein alpha

acts_upstream_of_or_within
involved_in

(MGI:3512696|PMID:15510220)

PMID:15510220

GO_REF:0000107 MGI:3512696

NCBI chr 4:82,018,585...82,132,938
Ensembl chr 4:92,737,608...92,850,600

sphingosine kinase 1

NCBI chr17:70,331,370...70,336,043
Ensembl chr17:75,883,329...75,886,481

syntaxin 1A

involved_in

PMID:12183029

GO_REF:0000107 RGD:1581173

Ensembl chr 7:80,852,495...80,862,255

STX1B

syntaxin 1B

involved_in

GO_REF:0000107

NCBI chr16:23,956,426...23,979,646
Ensembl chr16:31,356,907...31,378,870

UNC13A

unc-13 homolog A

acts_upstream_of_or_within

(MGI:2158119|PMID:11792326)

PMID:11792326

MGI:2158119

NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642

positive regulation of norepinephrine secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADORA2B

adenosine A2b receptor

NCBI chr17:34,849,466...34,880,088

KCNB1

potassium voltage-gated channel subfamily B member 1

involved_in

PMID:18167541

NCBI chr20:45,636,371...45,821,536
Ensembl chr20:46,776,274...46,885,521

OXT

oxytocin/neurophysin I prepropeptide

NCBI chr20:3,157,246...3,159,013

oxytocin receptor

NCBI chr 3:8,701,344...8,721,706

PLCD1

phospholipase C delta 1

NCBI chr 3:37,906,359...37,928,564
Ensembl chr 3:38,189,496...38,206,886

syntaxin 1A

involved_in

PMID:18167541

Ensembl chr 7:80,852,495...80,862,255

positive regulation of parathyroid hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

CYP27B1

cytochrome P450 family 27 subfamily B member 1

NCBI chr12:31,158,814...31,164,462
Ensembl chr12:31,419,773...31,424,822

FGFR1

fibroblast growth factor receptor 1

acts_upstream_of_or_within

(MGI:5548021|PMID:24259513)

PMID:24259513

MGI:5548021

NCBI chr 8:37,713,133...37,773,098
Ensembl chr 8:34,890,147...34,948,904

FGFR4

fibroblast growth factor receptor 4

acts_upstream_of_or_within

(MGI:5548021|PMID:24259513)

PMID:24259513

MGI:5548021

NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605

vitamin D receptor

NCBI chr12:40,828,413...40,891,700
Ensembl chr12:41,702,742...41,766,192

positive regulation of peptide hormone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

FGA

fibrinogen alpha chain

involved_in

(PMID:19193866)

PMID:19193866

NCBI chr 4:146,949,680...146,957,291

FGB

fibrinogen beta chain

involved_in

GO_REF:0000107

NCBI chr 4:146,929,561...146,937,665
Ensembl chr 4:158,747,659...158,755,766

FGG

fibrinogen gamma chain

involved_in

GO_REF:0000107

NCBI chr 4:146,970,671...146,979,348
Ensembl chr 4:158,788,966...158,797,237

GRP

gastrin releasing peptide

involved_in

(PMID:496973)

PMID:496973

NCBI chr18:52,614,169...52,626,427
Ensembl chr18:55,942,263...55,953,188

HFE

homeostatic iron regulator

involved_in

GO_REF:0000107

NCBI chr 6:25,921,663...25,930,852
Ensembl chr 6:26,580,358...26,588,591

ILDR1

immunoglobulin like domain containing receptor 1

acts_upstream_of_or_within
involved_in

(MGI:5514075|PMID:23863714)

PMID:23863714

GO_REF:0000107 MGI:5514075

NCBI chr 3:119,088,855...119,124,831
Ensembl chr 3:125,996,018...126,032,041

RASL10B

RAS like family 10 member B

involved_in

GO_REF:0000107

NCBI chr17:21,052,147...21,064,037
Ensembl chr17:21,346,472...21,355,788

SPINK1

serine peptidase inhibitor Kazal type 1

NCBI chr 5:143,273,137...143,287,745

TFR2

transferrin receptor 2

involved_in

GO_REF:0000107

NCBI chr 7:92,647,431...92,669,889
Ensembl chr 7:106,048,935...106,069,238

positive regulation of progesterone secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

mitofusin 2

NCBI chr 1:10,729,933...10,764,865
Ensembl chr 1:11,945,880...11,981,077

resistin

NCBI chr19:6,958,536...6,960,032
Ensembl chr19:7,812,942...7,814,909

positive regulation of prolactin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ABAT

4-aminobutyrate aminotransferase

NCBI chr16:7,609,282...7,718,049
Ensembl chr16:8,888,178...8,958,420

EGFR

epidermal growth factor receptor

NCBI chr 7:55,614,042...55,807,285
Ensembl chr 7:56,046,296...56,111,615

NMU

neuromedin U

involved_in

PMID:28874765

NCBI chr 4:68,299,538...68,340,680
Ensembl chr 4:74,867,364...74,904,965

positive regulation of prostaglandin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

endothelin 1

NCBI chr 6:12,076,312...12,142,861
Ensembl chr 6:12,462,718...12,503,545

interleukin 1 alpha

NCBI chr2A:89,273,482...89,284,421
Ensembl chr2A:113,784,854...113,795,801

IL1B

interleukin 1 beta

involved_in

(MGI:4413614|PMID:19940926)

PMID:19940926

MGI:4413614

NCBI chr2A:89,216,313...89,223,358
Ensembl chr2A:113,846,306...113,853,424

MAP2K6

mitogen-activated protein kinase kinase 6

NCBI chr17:63,342,720...63,483,926
Ensembl chr17:68,730,011...68,870,454

MAPK9

mitogen-activated protein kinase 9

NCBI chr 5:175,437,167...175,495,469
Ensembl chr 5:182,748,381...182,795,135

OXT

oxytocin/neurophysin I prepropeptide

NCBI chr20:3,157,246...3,159,013

P2RX7

purinergic receptor P2X 7

acts_upstream_of_or_within

(MGI:3616954|PMID:16269410)

PMID:16269410

MGI:3616954

NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068

P2RY2

purinergic receptor P2Y2

NCBI chr11:68,294,366...68,319,118
Ensembl chr11:71,532,958...71,534,091

PLA2G10

phospholipase A2 group X

involved_in

(PMID:18511424)

PMID:18511424

NCBI chr16:13,600,152...13,622,629

PLA2G3

phospholipase A2 group III

acts_upstream_of_or_within
involved_in

(MGI:6108995|PMID:28947740)

PMID:28947740

GO_REF:0000107 MGI:6108995

NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160

PLA2G4A

phospholipase A2 group IVA

acts_upstream_of_or_within
involved_in

(MGI:5779244|PMID:26828067)

PMID:26828067

GO_REF:0000107 MGI:5779244

NCBI chr 1:162,362,600...162,521,974
Ensembl chr 1:166,512,870...166,672,101

PTGES

prostaglandin E synthase

acts_upstream_of_or_within
involved_in

(MGI:5779244|PMID:26828067)

PMID:26828067

GO_REF:0000107 MGI:5779244

NCBI chr 9:100,865,702...100,880,408
Ensembl chr 9:129,522,547...129,537,020

TRPV4

transient receptor potential cation channel subfamily V member 4

involved_in

(PMID:19790068)

PMID:19790068

NCBI chr12:107,359,005...107,409,359
Ensembl chr12:110,754,238...110,786,182

positive regulation of prostaglandin secretion involved in immune response

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

MIF

macrophage migration inhibitory factor

involved_in

(MGI:2156302|PMID:11756671)

PMID:11756671

MGI:2156302

NCBI chr22:4,646,986...4,647,831
Ensembl chr22:22,730,807...22,732,009

positive regulation of renin secretion into blood stream

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

F2RL1

F2R like trypsin receptor 1

involved_in

GO_REF:0000107

NCBI chr 5:38,462,521...38,478,882
Ensembl chr 5:39,006,331...39,024,265

LOC100976603

olfactory receptor 51E2

involved_in

GO_REF:0000107

NCBI chr11:4,853,325...4,871,457
Ensembl chr11:4,520,050...4,521,012

positive regulation of serotonin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

corticotropin releasing hormone receptor 2

NCBI chr 7:31,265,619...31,313,902
Ensembl chr 7:31,386,026...31,434,220

galectin 3

NCBI chr14:35,715,850...35,732,263
Ensembl chr14:53,990,023...54,006,412

SLC6A4

solute carrier family 6 member 4

NCBI chr17:26,546,177...26,572,301
Ensembl chr17:27,050,900...27,092,882

positive regulation of somatostatin secretion

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

ADCYAP1

adenylate cyclase activating polypeptide 1

NCBI chr18:13,414,618...13,421,668
Ensembl chr18:15,713,479...15,717,749

CCKAR

cholecystokinin A receptor

NCBI chr 4:20,881,340...20,890,986
Ensembl chr 4:26,157,702...26,166,773

CCKBR

cholecystokinin B receptor

NCBI chr11:6,393,435...6,405,821
Ensembl chr11:6,075,816...6,088,145

GAL

galanin and GMAP prepropeptide

involved_in

(PMID:8837218)