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ONTOLOGY REPORT - ANNOTATIONS

Term:respiratory electron transport chain
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Accession:GO:0022904 term browser browse the term
Definition:A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
Synonyms:exact_synonym: electron transfer
 related_synonym: 6-phosphofructokinase reduction;   dihydrobiopterin reduction;   dihydrolipoamide reduction;   dihydrolipoylprotein reduction;   dihydropteridine reduction;   other pathways of electron transport;   oxidized glutathione reduction;   protein-disulfide reduction
 xref: Wikipedia:Electron_transfer

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respiratory electron transport chain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coq7 coenzyme Q7, hydroxylase acts_upstream_of_or_within ISO (MGI:2154595|PMID:11585841), (MGI:4359329|PMID:19478076) MGI PMID:11585841 PMID:19478076 MGI:2154595 MGI:4359329 NCBI chrNW_004955442:3,026,458...3,033,582
Ensembl chrNW_004955442:3,025,484...3,033,582 		JBrowse link
G Etfa electron transfer flavoprotein subunit alpha involved_in ISO (PMID:25416781) ComplexPortal PMID:25416781 NCBI chrNW_004955450:1,392,526...1,451,591
Ensembl chrNW_004955450:1,392,479...1,451,591 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta involved_in ISO (PMID:25416781) ComplexPortal PMID:25416781 NCBI chrNW_004955558:1,032,743...1,046,300
Ensembl chrNW_004955558:1,032,743...1,046,300 		JBrowse link
G Etfrf1 electron transfer flavoprotein regulatory factor 1 involved_in ISO (PMID:27499296) UniProt PMID:27499296 NCBI chrNW_004955413:20,287,287...20,294,430
Ensembl chrNW_004955413:20,293,398...20,293,738 		JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (MGI:5501380|PMID:23707074) MGI PMID:23707074 MGI:5501380 NCBI chrNW_004955545:1,682,097...1,689,373
Ensembl chrNW_004955545:1,682,097...1,689,376 		JBrowse link
G Immp2l inner mitochondrial membrane peptidase subunit 2 acts_upstream_of_or_within ISO (MGI:5299279|PMID:21824519) MGI PMID:21824519 MGI:5299279 NCBI chrNW_004955410:14,567,787...15,420,025
Ensembl chrNW_004955410:14,567,951...15,354,190 		JBrowse link
G LOC102014998 cytochrome b-c1 complex subunit Rieske, mitochondrial involved_in ISO (PMID:31883641) UniProt PMID:31883641 NCBI chrNW_004955468:8,331,153...8,338,628
Ensembl chrNW_004955468:8,331,153...8,338,628 		JBrowse link
G LOC106146232 protein SCO2 homolog, mitochondrial acts_upstream_of_or_within ISO (MGI:4412318|PMID:19837698) MGI PMID:19837698 MGI:4412318 NCBI chrNW_004955413:33,503,882...33,505,417 JBrowse link
G Mybbp1a MYB binding protein 1a acts_upstream_of_or_within ISO (MGI:3032469|PMID:14744933) MGI PMID:14744933 MGI:3032469 NCBI chrNW_004955467:12,390,371...12,405,055
Ensembl chrNW_004955467:12,390,037...12,404,971 		JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 acts_upstream_of_or_within ISO (MGI:5548237|PMID:24154540) MGI PMID:24154540 MGI:5548237 NCBI chrNW_004955479:5,065,948...5,080,215
Ensembl chrNW_004955479:5,064,652...5,080,215 		JBrowse link
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 acts_upstream_of_or_within ISO (MGI:6277626|PMID:30391276) MGI PMID:30391276 MGI:6277626 NCBI chrNW_004955446:13,764,907...13,864,824
Ensembl chrNW_004955446:13,764,907...13,864,824 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 acts_upstream_of_or_within ISO (MGI:5319010|PMID:22474353) MGI PMID:22474353 MGI:5319010 NCBI chrNW_004955504:893,112...903,282
Ensembl chrNW_004955504:893,112...903,282 		JBrowse link
G Pink1 PTEN induced kinase 1 involved_in ISO (MGI:3813389|PMID:18687901) ParkinsonsUK-UCL PMID:18687901 MGI:3813389 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
G Plec plectin involved_in ISO (MGI:5660667|PMID:26019234) MGI PMID:26019234 MGI:5660667 NCBI chrNW_004955454:2,583,138...2,644,308
Ensembl chrNW_004955454:2,583,138...2,643,211 		JBrowse link
G Polg2 DNA polymerase gamma 2, accessory subunit acts_upstream_of_or_within ISO (MGI:5465384|PMID:23197651) MGI PMID:23197651 MGI:5465384 NCBI chrNW_004955478:7,376,240...7,396,647
Ensembl chrNW_004955478:7,376,712...7,396,647 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha acts_upstream_of_or_within ISO (MGI:3032469|PMID:14744933) MGI PMID:14744933 MGI:3032469 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Pum2 pumilio RNA binding family member 2 involved_in ISO (MGI:6304097|PMID:30735131) MGI PMID:30735131 MGI:6304097 NCBI chrNW_004955469:2,810,825...2,886,911
Ensembl chrNW_004955469:2,810,573...2,886,611 		JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A involved_in ISO (PMID:7550341) RGD
UniProt		 PMID:7550341 PMID:16520240 RGD:2306906 NCBI chrNW_004955504:36,939...66,507
Ensembl chrNW_004955504:36,911...70,494 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B ISO RGD PMID:16520240 RGD:2306906 NCBI chrNW_004955527:1,769,280...1,792,496
Ensembl chrNW_004955527:1,768,940...1,792,361 		JBrowse link
G Sod2 superoxide dismutase 2 acts_upstream_of_or_within ISO (MGI:1931647|PMID:11226230), (MGI:4359329|PMID:19478076) MGI PMID:11226230 PMID:19478076 MGI:1931647 MGI:4359329 NCBI chrNW_004955439:21,209,101...21,223,538
Ensembl chrNW_004955439:21,209,101...21,224,163 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in ISO (MGI:5431290|PMID:22486171) MGI PMID:22486171 MGI:5431290 NCBI chrNW_004955424:20,329,009...20,443,652
Ensembl chrNW_004955424:20,327,754...20,445,980 		JBrowse link
aerobic electron transport chain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a51 solute carrier family 25 member 51 acts_upstream_of
involved_in		 ISO (PMID:33262325)
(PMID:33087354)		 UniProt PMID:33087354 PMID:33262325 NCBI chrNW_004955419:28,580,055...28,594,049 JBrowse link
glycerophosphate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpd1 glycerol-3-phosphate dehydrogenase 1 acts_upstream_of_or_within ISO (MGI:1927687|PMID:11147825) MGI PMID:11147825 MGI:1927687 NCBI chrNW_004955547:676,661...683,906
Ensembl chrNW_004955547:676,342...690,777 		JBrowse link
malate-aspartate shuttle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc1a3 solute carrier family 1 member 3 ISO RGD PMID:15242733 RGD:1642939 NCBI chrNW_004955426:21,371,985...21,450,749
Ensembl chrNW_004955426:21,371,985...21,451,069 		JBrowse link
G Slc25a12 solute carrier family 25 member 12 acts_upstream_of_or_within
involved_in		 ISO (MGI:3708219|PMID:17213189)
(PMID:11566871)		 RGD
MGI
UniProt		 PMID:11566871 PMID:17213189 PMID:19764902 MGI:3708219 RGD:13628741 NCBI chrNW_004955449:3,093,603...3,182,513
Ensembl chrNW_004955449:3,093,603...3,186,737 		JBrowse link
G Slc25a13 solute carrier family 25 member 13 involved_in
acts_upstream_of_or_within		 ISO (PMID:11566871)
(MGI:3708219|PMID:17213189)		 UniProt
MGI		 PMID:11566871 PMID:17213189 MGI:3708219 NCBI chrNW_004955432:12,685,253...12,788,307
Ensembl chrNW_004955432:12,684,596...12,826,667 		JBrowse link
mitochondrial ATP synthesis coupled electron transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bid BH3 interacting domain death agonist acts_upstream_of_or_within ISO (MGI:5662300|PMID:26219591) MGI PMID:26219591 MGI:5662300 NCBI chrNW_004955454:5,776,656...5,785,500
Ensembl chrNW_004955454:5,777,667...5,783,118 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase acts_upstream_of_or_within ISO (MGI:3820177|PMID:18635541) MGI PMID:18635541 MGI:3820177 NCBI chrNW_004955442:3,026,458...3,033,582
Ensembl chrNW_004955442:3,025,484...3,033,582 		JBrowse link
G Dguok deoxyguanosine kinase ISO RGD PMID:30404003 RGD:15039296 NCBI chrNW_004955424:11,739,904...11,773,884
Ensembl chrNW_004955424:11,738,859...11,773,902 		JBrowse link
G LOC102028200 cytochrome c oxidase assembly factor 6 homolog involved_in ISO (PMID:24549041), (PMID:25959673) UniProt PMID:24549041 PMID:25959673 NCBI chrNW_004955492:5,316,594...5,324,913 JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO (MGI:5662300|PMID:26219591) MGI PMID:26219591 MGI:5662300 NCBI chrNW_004955422:672,301...690,989
Ensembl chrNW_004955422:672,301...690,989 		JBrowse link
G Ndufa12 NADH:ubiquinone oxidoreductase subunit A12 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955405:31,607,182...31,621,538
Ensembl chrNW_004955405:31,606,924...31,621,590 		JBrowse link
G Ndufb6 NADH:ubiquinone oxidoreductase subunit B6 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955472:3,054,026...3,064,530
Ensembl chrNW_004955472:3,054,154...3,064,433 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955468:12,961,873...12,971,278
Ensembl chrNW_004955468:12,961,915...12,971,095 		JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955422:17,876,496...17,881,773
Ensembl chrNW_004955422:17,873,872...17,881,773 		JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955407:39,029,943...39,039,425
Ensembl chrNW_004955407:39,026,057...39,039,347 		JBrowse link
G Snca synuclein alpha acts_upstream_of_or_within ISO (MGI:3607411|PMID:16260631) MGI PMID:16260631 MGI:3607411 NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403 		JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase involved_in ISO (PMID:15304507) BHF-UCL PMID:15304507 NCBI chrNW_004955580:915,668...921,703
Ensembl chrNW_004955580:915,188...922,791 		JBrowse link
mitochondrial electron transport, cytochrome c to oxygen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afg1l AFG1 like ATPase involved_in ISO (PMID:27323408) UniProt PMID:27323408 NCBI chrNW_004955411:33,386,568...33,617,721
Ensembl chrNW_004955411:33,386,098...33,617,721 		JBrowse link
G LOC102018506 cytochrome c oxidase subunit 4 isoform 2, mitochondrial involved_in ISO (PMID:11311561) UniProt PMID:11311561 NCBI chrNW_004955422:29,320,720...29,329,082
Ensembl chrNW_004955422:29,320,720...29,329,127 		JBrowse link
G LOC102023786 cytochrome c, somatic ISO RGD PMID:10980192 RGD:2300408 NCBI chrNW_004955410:27,086,405...27,089,255
Ensembl chrNW_004955410:27,086,405...27,089,255 		JBrowse link
mitochondrial electron transport, NADH to ubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor ISO RGD PMID:15341590 RGD:1358393 NCBI chrNW_004955476:6,773,244...6,822,201
Ensembl chrNW_004955476:6,772,088...6,822,588 		JBrowse link
G Coq9 coenzyme Q9 acts_upstream_of_or_within ISO (MGI:5468078|PMID:23255162) MGI PMID:23255162 MGI:5468078 NCBI chrNW_004955433:15,081,390...15,094,441
Ensembl chrNW_004955433:15,081,390...15,094,441 		JBrowse link
G Dld dihydrolipoamide dehydrogenase acts_upstream_of_or_within ISO (MGI:3622835|PMID:15009635) MGI PMID:15009635 MGI:3622835 NCBI chrNW_004955410:12,212,981...12,238,561
Ensembl chrNW_004955410:12,212,963...12,238,561 		JBrowse link
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 acts_upstream_of ISO (MGI:5529421|PMID:23530063) MGI PMID:23530063 MGI:5529421 NCBI chrNW_004955518:941,610...1,016,097
Ensembl chrNW_004955518:941,336...1,016,968 		JBrowse link
G Ndufa10 NADH:ubiquinone oxidoreductase subunit A10 acts_upstream_of_or_within ISO (MGI:5568152|PMID:24652937) MGI PMID:24652937 MGI:5568152 NCBI chrNW_004955542:1,329,802...1,370,109
Ensembl chrNW_004955542:1,329,212...1,370,695 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 involved_in ISO (PMID:31557978) UniProt PMID:31557978 NCBI chrNW_004955457:8,838,216...8,879,059
Ensembl chrNW_004955457:8,838,216...8,883,481 		JBrowse link
G Ndufs2 NADH:ubiquinone oxidoreductase core subunit S2 involved_in ISO (PMID:30922174) UniProt PMID:30922174 RGD:42722001 NCBI chrNW_004955468:12,961,873...12,971,278
Ensembl chrNW_004955468:12,961,915...12,971,095 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 involved_in ISO (PMID:14729820), (PMID:30140060)
(MGI:6391555|PMID:31916679), (MGI:6505357|PMID:33148885)		 UniProt PMID:14729820 PMID:30140060 PMID:31916679 PMID:33148885 MGI:6391555 MGI:6505357 NCBI chrNW_004955422:713,370...717,926
Ensembl chrNW_004955422:709,784...717,926 		JBrowse link
G Ndufs7 NADH:ubiquinone oxidoreductase core subunit S7 involved_in ISO (PMID:17275378) UniProt PMID:17275378 NCBI chrNW_004955495:6,540,360...6,548,072
Ensembl chrNW_004955495:6,540,450...6,547,975 		JBrowse link
G Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 involved_in ISO (PMID:22499348) UniProt PMID:22499348 NCBI chrNW_004955422:17,781,374...17,785,395
Ensembl chrNW_004955422:17,781,204...17,784,404 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 involved_in ISO (PMID:12754703) UniProt PMID:12754703 NCBI chrNW_004955402:2,802,366...2,818,049
Ensembl chrNW_004955402:2,800,447...2,818,375 		JBrowse link
mitochondrial electron transport, succinate to ubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sdhaf2 succinate dehydrogenase complex assembly factor 2 involved_in ISO (PMID:19628817) UniProt PMID:19628817 NCBI chrNW_004955511:6,125,966...6,139,098
Ensembl chrNW_004955511:6,125,966...6,139,098 		JBrowse link
mitochondrial electron transport, ubiquinol to cytochrome c term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102005965 cytochrome b-c1 complex subunit 1, mitochondrial acts_upstream_of_or_within ISO (MGI:3640022|PMID:16782889) MGI PMID:16782889 MGI:3640022 NCBI chrNW_004955532:685,315...691,286
Ensembl chrNW_004955532:685,395...696,554 		JBrowse link
G LOC102013363 ubiquinol-cytochrome-c reductase complex assembly factor 3 involved_in ISO (PMID:25008109) UniProt PMID:25008109 NCBI chrNW_004955599:540,598...541,643
Ensembl chrNW_004955599:526,609...541,643 		JBrowse link
negative regulation of mitochondrial electron transport, NADH to ubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc15 DnaJ heat shock protein family (Hsp40) member C15 acts_upstream_of_or_within ISO (MGI:5529421|PMID:23530063) MGI PMID:23530063 MGI:5529421 NCBI chrNW_004955518:941,610...1,016,097
Ensembl chrNW_004955518:941,336...1,016,968 		JBrowse link
plasma membrane ATP synthesis coupled electron transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC102028200 cytochrome c oxidase assembly factor 6 homolog involved_in ISO (PMID:26160915) UniProt PMID:26160915 NCBI chrNW_004955492:5,316,594...5,324,913 JBrowse link
positive regulation of mitochondrial ATP synthesis coupled electron transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnb1 cyclin B1 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955446:140,661...149,500
Ensembl chrNW_004955446:140,093...149,500 		JBrowse link
G Cdk1 cyclin dependent kinase 1 involved_in ISO (PMID:24746669) CAFA PMID:24746669 NCBI chrNW_004955425:14,210,681...14,226,474
Ensembl chrNW_004955425:14,210,680...14,226,474 		JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 involved_in ISO (PMID:28589937) FlyBase PMID:28589937 NCBI chrNW_004955456:8,260,533...8,265,488
Ensembl chrNW_004955456:8,255,898...8,265,488 		JBrowse link
positive regulation of mitochondrial electron transport, NADH to ubiquinone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iscu iron-sulfur cluster assembly enzyme involved_in ISO (PMID:20436681) ARUK-UCL PMID:20436681 NCBI chrNW_004955455:9,833,924...9,840,547
Ensembl chrNW_004955455:9,833,924...9,841,619 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO (PMID:19822128)
(MGI:5582165|PMID:19822128)		 ParkinsonsUK-UCL PMID:19822128 MGI:5582165 NCBI chrNW_004955486:4,974,130...4,985,927
Ensembl chrNW_004955486:4,969,497...4,985,885 		JBrowse link
G Pink1 PTEN induced kinase 1 acts_upstream_of_or_within ISO (MGI:5568152|PMID:24652937) MGI PMID:24652937 MGI:5568152 NCBI chrNW_004955452:1,171,115...1,186,338
Ensembl chrNW_004955452:1,171,205...1,185,125 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12345
    metabolic process 7852
      cellular metabolic process 4954
        generation of precursor metabolites and energy 351
          electron transport chain 63
            respiratory electron transport chain 58
              ATP synthesis coupled electron transport + 34
              aerobic electron transport chain + 21
              anaerobic electron transport chain 0
              chlororespiration 0
              glycerophosphate shuttle 1
              malate-aspartate shuttle 3
              plasma membrane electron transport, NADH to quinone 0
Path 2
Term Annotations click to browse term
  biological_process 12345
    metabolic process 7852
      cellular metabolic process 4954
        generation of precursor metabolites and energy 351
          energy derivation by oxidation of organic compounds 244
            cellular respiration 162
              respiratory electron transport chain 58
                ATP synthesis coupled electron transport + 34
                aerobic electron transport chain + 21
                anaerobic electron transport chain 0
                chlororespiration 0
                glycerophosphate shuttle 1
                malate-aspartate shuttle 3
                plasma membrane electron transport, NADH to quinone 0
paths to the root