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ONTOLOGY REPORT - ANNOTATIONS

Term:GABA-gated chloride ion channel activity
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Accession:GO:0022851 term browser browse the term
Definition:Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.


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GABA-gated chloride ion channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GABRA1 gamma-aminobutyric acid type A receptor subunit alpha1 contributes_to
enables		 ISO
IEA
IBA		 (PMID:23909897)
(PMID:27129275)		 UniProt
Ensembl
GO_Central		 PMID:23909897 PMID:27129275 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:49,006,981...49,065,205
Ensembl chr 4:49,009,495...49,062,581 		JBrowse link
G GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr13:42,367,988...42,488,069
Ensembl chr13:42,368,949...42,488,075 		JBrowse link
G GABRA3 gamma-aminobutyric acid type A receptor subunit alpha3 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:120,152,650...120,460,604
Ensembl chr  X:120,153,261...120,460,119 		JBrowse link
G GABRA4 gamma-aminobutyric acid type A receptor subunit alpha4 enables IBA GO_Central GO_REF:0000033 NCBI chr13:42,889,100...42,958,604
Ensembl chr13:42,897,655...42,959,206 		JBrowse link
G GABRA5 gamma-aminobutyric acid type A receptor subunit alpha5 enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr 3:33,663,414...33,746,120
Ensembl chr 3:33,664,169...33,744,328 		JBrowse link
G GABRA6 gamma-aminobutyric acid type A receptor subunit alpha6 contributes_to
enables		 ISO
IBA		 RGD
GO_Central		 PMID:17395622 GO_REF:0000033 RGD:1626515 NCBI chr 4:49,208,691...49,225,754
Ensembl chr 4:49,208,605...49,226,212 		JBrowse link
G GABRB1 gamma-aminobutyric acid type A receptor subunit beta1 enables ISO (PMID:26950270)
(PMID:16412217), (PMID:2538761), (PMID:9039914)		 UniProt PMID:2538761 PMID:9039914 PMID:16412217 PMID:26950270 NCBI chr13:43,011,491...43,349,876
Ensembl chr13:42,992,569...43,349,923 		JBrowse link
G GABRB2 gamma-aminobutyric acid type A receptor subunit beta2 contributes_to IEA Ensembl GO_REF:0000107 NCBI chr 4:49,342,527...49,579,697
Ensembl chr 4:49,342,508...49,578,092 		JBrowse link
G GABRB3 gamma-aminobutyric acid type A receptor subunit beta3 enables
contributes_to		 IEA Ensembl GO_REF:0000107 NCBI chr 3:33,878,948...34,101,987
Ensembl chr 3:33,878,904...34,097,764 		JBrowse link
G GABRE gamma-aminobutyric acid type A receptor subunit epsilon enables IEA
IBA		 Ensembl
GO_Central		 GO_REF:0000033 GO_REF:0000107 NCBI chr  X:119,913,867...119,937,867
Ensembl chr  X:119,913,867...119,937,909 		JBrowse link
G GABRG1 gamma-aminobutyric acid type A receptor subunit gamma1 enables IBA GO_Central GO_REF:0000033 NCBI chr13:42,194,929...42,276,379
Ensembl chr13:42,200,202...42,276,711 		JBrowse link
G GABRG2 gamma-aminobutyric acid type A receptor subunit gamma2 enables
contributes_to		 IBA
IEA		 GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107 NCBI chr 4:48,794,770...48,901,859
Ensembl chr 4:48,796,852...48,901,548 		JBrowse link
G GABRG3 gamma-aminobutyric acid type A receptor subunit gamma3 enables IBA GO_Central GO_REF:0000033 NCBI chr 3:32,956,061...33,641,971
Ensembl chr 3:32,964,122...33,642,686 		JBrowse link
G GABRP gamma-aminobutyric acid type A receptor subunit pi enables IEA Ensembl GO_REF:0000107 NCBI chr 4:41,164,725...41,186,716
Ensembl chr 4:41,166,453...41,184,589 		JBrowse link
G GABRQ gamma-aminobutyric acid type A receptor subunit theta enables IEA Ensembl GO_REF:0000107 NCBI chr  X:120,607,815...120,630,251
Ensembl chr  X:120,607,686...120,628,343 		JBrowse link
G GABRR1 gamma-aminobutyric acid type A receptor subunit rho1 enables ISO PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr12:48,431,273...48,465,426
Ensembl chr12:48,431,379...48,538,037 		JBrowse link
G GABRR2 gamma-aminobutyric acid type A receptor subunit rho2 enables ISO PMID:8524843 UniProt PMID:8524843 RGD:728796 NCBI chr12:48,492,607...48,537,961
Ensembl chr12:48,431,379...48,538,037 		JBrowse link
G GABRR3 gamma-aminobutyric acid type A receptor rho3 subunit enables ISO PMID:11861315 UniProt PMID:11861315 RGD:405650323 NCBI chr33:5,013,983...5,036,304 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21958
    molecular transducer activity 1885
      signaling receptor activity 1885
        neurotransmitter receptor activity 103
          transmitter-gated channel activity 64
            transmitter-gated monoatomic ion channel activity 64
              GABA-gated chloride ion channel activity 18
Path 2
Term Annotations click to browse term
  molecular_function 21958
    transporter activity 1275
      transmembrane transporter activity 1168
        passive transmembrane transporter activity 532
          channel activity 532
            gated channel activity 336
              ligand-gated channel activity 194
                ligand-gated monoatomic ion channel activity 189
                  extracellular ligand-gated monoatomic ion channel activity 76
                    transmitter-gated monoatomic ion channel activity 64
                      GABA-gated chloride ion channel activity 18
paths to the root