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ONTOLOGY REPORT - ANNOTATIONS

Term:acetylcholine-gated monoatomic cation-selective channel activity
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Accession:GO:0022848 term browser browse the term
Definition:Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
Synonyms:exact_synonym: acetylcholine-activated cation-selective channel activity;   acetylcholine-gated cation channel activity;   ionotropic acetylcholine receptor activity;   nAChR;   nicotinergic acetylcholine receptor activity;   nicotinic acetylcholine-activated cation-selective channel activity
 broad_synonym: acetylcholine-gated cation-selective channel activity
 alt_id: GO:0004889;   GO:0016904


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acetylcholine-gated monoatomic cation-selective channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CHRNA1 cholinergic receptor nicotinic alpha 1 subunit enables
contributes_to		 ISO
IEA		 (PMID:2383398) RGD
InterPro
Ensembl
MGI		 PMID:1702709 PMID:2383398 PMID:22461452 GO_REF:0000002 GO_REF:0000107 RGD:68734 RGD:8549758 NCBI chr36:18,726,243...18,742,505
Ensembl chr36:18,726,243...18,742,505 		JBrowse link
G CHRNA10 cholinergic receptor nicotinic alpha 10 subunit enables IEA InterPro
Ensembl
TreeGrafter		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr21:26,216,862...26,233,226 JBrowse link
G CHRNA2 cholinergic receptor nicotinic alpha 2 subunit enables ISO
IEA		 RGD
InterPro
Ensembl
TreeGrafter		 PMID:2832952 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:728252 NCBI chr25:30,117,384...30,137,223
Ensembl chr25:30,117,239...30,135,599 		JBrowse link
G CHRNA3 cholinergic receptor nicotinic alpha 3 subunit enables ISO
IEA		 RGD
InterPro
Ensembl		 PMID:11297818 GO_REF:0000002 GO_REF:0000107 RGD:1643016 NCBI chr13:38,330,287...38,343,142
Ensembl chr13:38,328,814...38,346,246 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit enables ISO
IEA		 RGD
InterPro
Ensembl
TreeGrafter		 PMID:11259617 PMID:12202488 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:727641 RGD:8549520 NCBI chr24:47,024,948...47,036,507
Ensembl chr24:47,025,187...47,042,266 		JBrowse link
G CHRNA5 cholinergic receptor nicotinic alpha 5 subunit enables ISO
IEA		 RGD
InterPro
TreeGrafter		 PMID:11297818 PMID:12814364 GO_REF:0000002 GO_REF:0000118 RGD:1298760 RGD:1643016 NCBI chr13:38,343,966...38,355,534
Ensembl chr13:38,346,104...38,355,468 		JBrowse link
G CHRNA6 cholinergic receptor nicotinic alpha 6 subunit enables IEA InterPro GO_REF:0000002 NCBI chr16:22,990,377...23,009,257
Ensembl chr16:22,990,167...23,009,106 		JBrowse link
G CHRNA7 cholinergic receptor nicotinic alpha 7 subunit enables ISO
IEA		 RGD
InterPro
Ensembl
TreeGrafter		 PMID:11259617 PMID:11297818 PMID:12069582 PMID:16186249 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:1600971 RGD:1643016 RGD:727702 RGD:8549520 NCBI chr 3:36,852,082...37,164,930
Ensembl chr 3:36,852,543...36,978,399 		JBrowse link
G CHRNA9 cholinergic receptor nicotinic alpha 9 subunit enables ISO
IEA		 RGD
InterPro
Ensembl
TreeGrafter		 PMID:7954834 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:728400 NCBI chr 3:72,190,431...72,204,092
Ensembl chr 3:72,190,555...72,203,404 		JBrowse link
G CHRNB1 cholinergic receptor nicotinic beta 1 subunit enables
contributes_to		 ISO
IEA		 (PMID:2383398) RGD
InterPro
Ensembl
TreeGrafter
MGI		 PMID:1702709 PMID:2383398 PMID:22461452 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:68734 RGD:8549758 NCBI chr 5:32,375,152...32,383,517
Ensembl chr 5:32,375,215...32,382,929 		JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit enables ISO
IEA		 RGD
InterPro
Ensembl
TreeGrafter		 PMID:11259617 PMID:11956333 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:727635 RGD:8549520 NCBI chr 7:42,786,505...42,797,976
Ensembl chr 7:42,789,600...42,795,722 		JBrowse link
G CHRNB3 cholinergic receptor nicotinic beta 3 subunit enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr16:23,021,652...23,040,907
Ensembl chr16:23,021,645...23,048,347 		JBrowse link
G CHRNB4 cholinergic receptor nicotinic beta 4 subunit enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr13:38,312,537...38,327,242
Ensembl chr13:38,312,173...38,328,341 		JBrowse link
G CHRND cholinergic receptor nicotinic delta subunit enables
contributes_to		 ISO
IEA		 (PMID:2383398) RGD
InterPro
Ensembl
TreeGrafter
MGI		 PMID:1702709 PMID:2383398 PMID:22461452 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 RGD:68734 RGD:8549758 NCBI chr25:44,166,089...44,175,047
Ensembl chr25:44,165,819...44,174,216 		JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit enables
contributes_to		 ISO
IEA		 (PMID:2383398) RGD
InterPro
TreeGrafter
MGI		 PMID:2383398 PMID:22461452 GO_REF:0000002 GO_REF:0000118 RGD:8549758 NCBI chr 5:31,696,710...31,707,639
Ensembl chr 5:31,696,993...31,708,671 		JBrowse link
G CHRNG cholinergic receptor nicotinic gamma subunit enables ISO
IEA		 RGD
InterPro
TreeGrafter		 PMID:1702709 PMID:22461452 GO_REF:0000002 GO_REF:0000118 RGD:68734 RGD:8549758 NCBI chr25:44,178,149...44,183,623
Ensembl chr25:44,178,181...44,183,626 		JBrowse link
G HTR3A 5-hydroxytryptamine receptor 3A enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:19,324,087...19,338,250
Ensembl chr 5:19,324,444...19,338,294 		JBrowse link
G HTR3B 5-hydroxytryptamine receptor 3B enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:19,361,011...19,393,206
Ensembl chr 5:19,362,382...19,414,912 		JBrowse link
G HTR3C 5-hydroxytryptamine receptor 3C enables IEA TreeGrafter GO_REF:0000118 NCBI chr34:16,969,213...16,976,401 JBrowse link
G LOC100856260 5-hydroxytryptamine receptor 3E enables IEA TreeGrafter GO_REF:0000118 NCBI chr34:17,011,403...17,019,214
Ensembl chr34:17,011,555...17,018,941 		JBrowse link
G LOC478649 5-hydroxytryptamine receptor 3C-like enables IEA TreeGrafter GO_REF:0000118 NCBI chr34:16,958,296...16,961,863
Ensembl chr34:16,958,083...16,961,857 		JBrowse link
G LOC488101 5-hydroxytryptamine receptor 3C-like enables IEA TreeGrafter GO_REF:0000118 NCBI chr34:16,983,633...16,988,539 JBrowse link
G NUP98 nucleoporin 98 and 96 precursor enables IEA TreeGrafter GO_REF:0000118 NCBI chr21:26,231,585...26,348,019
Ensembl chr21:26,220,963...26,336,020 		JBrowse link
G ZACN zinc activated ion channel enables IEA TreeGrafter GO_REF:0000118 NCBI chr 9:4,555,299...4,558,599
Ensembl chr 9:4,555,299...4,558,602 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18797
    transporter activity 1258
      transmembrane transporter activity 1168
        monoatomic ion transmembrane transporter activity 750
          monoatomic ion channel activity 467
            ligand-gated monoatomic ion channel activity 186
              ligand-gated monoatomic cation channel activity 133
                acetylcholine-gated monoatomic cation-selective channel activity 24
Path 2
Term Annotations click to browse term
  molecular_function 18797
    transporter activity 1258
      transmembrane transporter activity 1168
        passive transmembrane transporter activity 532
          channel activity 532
            gated channel activity 332
              ligand-gated channel activity 190
                ligand-gated monoatomic ion channel activity 186
                  extracellular ligand-gated monoatomic ion channel activity 75
                    transmitter-gated monoatomic ion channel activity 64
                      transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 60
                        acetylcholine-gated monoatomic cation-selective channel activity 24
paths to the root