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ONTOLOGY REPORT - ANNOTATIONS

Term:extracellular matrix disassembly
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Accession:GO:0022617 term browser browse the term
Definition:A process that results in the breakdown of the extracellular matrix.
Synonyms:xref: Reactome:R-HSA-1474228 "Degradation of the extracellular matrix"


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extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 involved_in ISO (PMID:23233679) UniProt PMID:23233679 NCBI chr 5:4,457,879...4,480,210
Ensembl chr 5:4,457,959...4,479,875 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr31:22,242,901...22,289,453
Ensembl chr31:22,248,092...22,289,802 		JBrowse link
G CAPG capping actin protein, gelsolin like NOT|involved_in ISO (PMID:24236012) UniProt PMID:24236012 NCBI chr17:39,619,429...39,640,944
Ensembl chr17:39,619,248...39,640,942 		JBrowse link
G CMA1 chymase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,438,244...4,441,189
Ensembl chr 8:4,438,244...4,441,189 		JBrowse link
G ENG endoglin involved_in ISO (PMID:18223685) BHF-UCL PMID:18223685 NCBI chr 9:55,558,246...55,590,081
Ensembl chr 9:55,558,305...55,589,064 		JBrowse link
G EXOC8 exocyst complex component 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:8,133,526...8,138,185
Ensembl chr 4:8,133,670...8,135,853 		JBrowse link
G EXOC8 exocyst complex component 8 involved_in IEA Ensembl GO_REF:0000107
G FLOT1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:517,941...528,677
Ensembl chr12:516,032...528,637 		JBrowse link
G GSN gelsolin NOT|involved_in ISO (PMID:24236012) UniProt PMID:24236012 NCBI chr11:74,248,227...74,268,129
Ensembl chr11:74,233,457...74,268,129 		JBrowse link
G KIF9 kinesin family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:41,587,202...41,637,768
Ensembl chr20:41,588,443...41,637,781 		JBrowse link
G KLK4 kallikrein related peptidase 4 acts_upstream_of_or_within ISO (PMID:22243248) MGI PMID:22243248 NCBI chr 1:105,950,948...105,955,464
Ensembl chr 1:105,951,691...106,007,581 		JBrowse link
G KLK4 kallikrein related peptidase 4 involved_in
acts_upstream_of_or_within 		IBA
IEA 		GO_Central
Ensembl		 GO_REF:0000033 GO_REF:0000107
G LAMC1 laminin subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:16,406,421...16,528,372
Ensembl chr 7:16,404,495...16,526,000 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:4,955,453...5,059,654
Ensembl chr22:4,992,347...5,059,636 		JBrowse link
G LOC100049001 tryptase involved_in ISO (PMID:27068509) BHF-UCL PMID:27068509 NCBI chr 6:39,505,485...39,506,909 JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:28,793,568...28,864,832
Ensembl chr 5:28,850,522...28,864,121 		JBrowse link
G MMP20 matrix metallopeptidase 20 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 5:29,106,717...29,154,628
Ensembl chr 5:29,106,717...29,155,071 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:38,951,926...38,956,134
Ensembl chr 6:38,953,741...38,956,115 		JBrowse link
G PBXIP1 PBX homeobox interacting protein 1 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr 7:42,514,306...42,524,056
Ensembl chr 7:42,514,423...42,523,585 		JBrowse link
G PLG plasminogen involved_in ISO (PMID:14699093) BHF-UCL PMID:14699093 NCBI chr 1:49,497,229...49,535,260
Ensembl chr 1:49,497,229...49,535,260 		JBrowse link
G SH3PXD2B SH3 and PX domains 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:39,854,213...39,950,704
Ensembl chr 4:39,854,211...39,949,958 		JBrowse link
G WASHC1 WASH complex subunit 1 involved_in ISO (PMID:24344185) UniProt PMID:24344185 NCBI chr27:42,102,694...42,118,850
Ensembl chr27:42,099,886...42,116,339 		JBrowse link
G WDR72 WD repeat domain 72 acts_upstream_of_or_within ISO (PMID:26247047) MGI PMID:26247047 NCBI chr30:19,120,021...19,340,781
Ensembl chr30:19,122,674...19,326,874 		JBrowse link
basement membrane disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMA1 chymase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,438,244...4,441,189
Ensembl chr 8:4,438,244...4,441,189 		JBrowse link
G CTSS cathepsin S involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:59,893,840...59,910,878
Ensembl chr17:59,893,840...59,910,849 		JBrowse link
G HPN hepsin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,486,308...117,503,127
Ensembl chr 1:117,486,340...117,502,583 		JBrowse link
biofilm matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSG cathepsin G involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,483,327...4,485,933
Ensembl chr 8:4,470,577...4,512,628 		JBrowse link
negative regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DPP4 dipeptidyl peptidase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:7,398,713...7,472,554
Ensembl chr36:7,399,643...7,454,204 		JBrowse link
G FAP fibroblast activation protein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:7,574,364...7,647,448
Ensembl chr36:7,575,161...7,647,226 		JBrowse link
G LOC607874 cystatin-C-like involved_in ISO (PMID:10545518) BHF-UCL PMID:10545518 NCBI chr23:49,562...53,618 JBrowse link
G MIR29C-2 microRNA mir-29c-2 acts_upstream_of ISO (PMID:23936390) BHF-UCL PMID:23936390 NCBI chr 7:6,651,339...6,651,396 JBrowse link
G MIR92A-1 microRNA mir-92a-1 acts_upstream_of ISO (PMID:23820254) BHF-UCL PMID:23820254 NCBI chr22:42,478,714...42,478,772 JBrowse link
G MIR92A-2 microRNA mir-92a-2 acts_upstream_of ISO (PMID:23820254) BHF-UCL PMID:23820254 NCBI chr  X:104,895,826...104,895,886
Ensembl chr  X:104,895,826...104,895,886 		JBrowse link
G MIR98 microRNA mir-98 involved_in ISO (PMID:26587789) ARUK-UCL PMID:26587789 NCBI chr  X:45,253,693...45,253,772
Ensembl chr  X:45,253,696...45,253,775 		JBrowse link
positive regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:81,792,683...81,804,274
Ensembl chr 5:81,792,155...81,804,152 		JBrowse link
G CLASP1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:24859005) UniProt PMID:24859005 NCBI chr19:28,563,189...28,830,503
Ensembl chr19:28,595,040...28,827,645 		JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) UniProt PMID:24859005 NCBI chr23:3,261,778...3,423,698
Ensembl chr23:3,246,522...3,421,716 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:20,002,984...20,152,930
Ensembl chr38:20,008,057...20,152,275 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:12,360,849...12,370,906
Ensembl chr 6:12,354,599...12,370,808 		JBrowse link
G IL6 interleukin 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:36,474,268...36,478,519
Ensembl chr14:36,473,394...36,478,519 		JBrowse link
G MELTF melanotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:29,985,007...30,006,437
Ensembl chr33:29,985,206...30,003,742 		JBrowse link
G PDPN podoplanin involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:83,552,735...83,581,375
Ensembl chr 2:83,552,830...83,581,375 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 acts_upstream_of ISO (PMID:23820254) BHF-UCL PMID:23820254 NCBI chr 9:20,539,660...20,614,631
Ensembl chr 9:20,539,697...20,612,672 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:13,430,832...13,511,655
Ensembl chr38:13,429,148...13,510,242 		JBrowse link
regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDR1 discoidin domain receptor tyrosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:653,800...671,190
Ensembl chr12:653,807...670,543 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO RGD PMID:16738537 RGD:2313717 NCBI chr 5:6,059,023...6,189,516
Ensembl chr 5:6,058,935...6,186,232 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:36,243,689...36,254,636
Ensembl chr 4:36,244,220...36,252,035 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 22130
    cellular process 21661
      cellular component organization or biogenesis 10073
        cellular component organization 9841
          cellular component disassembly 470
            extracellular matrix disassembly 46
              basement membrane disassembly + 3
              biofilm matrix disassembly 1
              negative regulation of extracellular matrix disassembly 7
              positive regulation of extracellular matrix disassembly 10
              regulation of extracellular matrix disassembly + 20
Path 2
Term Annotations click to browse term
  biological_process 22130
    cellular process 21661
      cellular component organization or biogenesis 10073
        cellular component organization 9841
          extracellular structure organization 340
            extracellular matrix organization 337
              extracellular matrix disassembly 46
                basement membrane disassembly + 3
                biofilm matrix disassembly 1
                negative regulation of extracellular matrix disassembly 7
                positive regulation of extracellular matrix disassembly 10
                regulation of extracellular matrix disassembly + 20
paths to the root