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ONTOLOGY REPORT - ANNOTATIONS

Term:extracellular matrix disassembly
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Accession:GO:0022617 term browser browse the term
Definition:A process that results in the breakdown of the extracellular matrix.
Synonyms:xref: Reactome:R-HSA-1474228 "Degradation of the extracellular matrix"


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extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif 15 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:125,264,129...125,291,655
Ensembl chr11:129,154,895...129,182,326 		JBrowse link
G ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif 5 involved_in ISO (PMID:23233679) UniProt PMID:23233679 NCBI chr21:13,352,222...13,402,165
Ensembl chr21:26,744,807...26,788,736 		JBrowse link
G CAPG capping actin protein, gelsolin like NOT|involved_in ISO (PMID:24236012) UniProt PMID:24236012 NCBI chr2A:85,447,296...85,466,677
Ensembl chr2A:86,997,891...87,016,263 		JBrowse link
G CMA1 chymase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:5,277,269...5,280,335
Ensembl chr14:23,400,345...23,403,548 		JBrowse link
G ENG endoglin involved_in ISO (PMID:18223685) BHF-UCL PMID:18223685 NCBI chr 9:98,934,080...98,973,862
Ensembl chr 9:127,605,608...127,644,641 		JBrowse link
G EXOC8 exocyst complex component 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:206,884,334...206,889,753
Ensembl chr 1:211,911,802...211,913,979 		JBrowse link
G FLOT1 flotillin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,472,839...30,487,809
Ensembl chr 6:31,342,033...31,357,559 		JBrowse link
G GSN gelsolin NOT|involved_in ISO (PMID:24236012) UniProt PMID:24236012 NCBI chr 9:92,413,819...92,460,483
Ensembl chr 9:120,741,148...120,805,831 		JBrowse link
G KIF9 kinesin family member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:47,130,047...47,183,636
Ensembl chr 3:48,229,703...48,283,002 		JBrowse link
G KLK4 kallikrein related peptidase 4 involved_in
acts_upstream_of_or_within 		IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chr19:47,849,158...47,876,522
Ensembl chr19:56,764,073...56,768,169 		JBrowse link
G KLK5 kallikrein related peptidase 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:47,909,823...47,920,671
Ensembl chr19:56,799,814...56,809,471 		JBrowse link
G LAMC1 laminin subunit gamma 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:158,541,635...158,663,836
Ensembl chr 1:162,700,704...162,822,534 		JBrowse link
G LCP1 lymphocyte cytosolic protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:26,820,846...26,906,916 JBrowse link
G LOC100982214 plasminogen involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:158,662,192...158,713,413
Ensembl chr 6:163,673,464...163,736,777 		JBrowse link
G MMP13 matrix metallopeptidase 13 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:97,890,811...97,902,778
Ensembl chr11:101,377,001...101,387,679 		JBrowse link
G MMP20 matrix metallopeptidase 20 acts_upstream_of_or_within IEA Ensembl GO_REF:0000107 NCBI chr11:97,518,573...97,566,881
Ensembl chr11:101,011,084...101,059,322 		JBrowse link
G NOXO1 NADPH oxidase organizer 1 involved_in ISO (PMID:19755710) UniProt PMID:19755710 NCBI chr16:720,087...725,567 JBrowse link
G PBXIP1 PBX homeobox interacting protein 1 acts_upstream_of_or_within ISO (PMID:30659184) MGI PMID:30659184 NCBI chr 1:130,292,611...130,304,667 JBrowse link
G SH3PXD2B SH3 and PX domains 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:167,678,633...167,807,960
Ensembl chr 5:174,591,759...174,719,957 		JBrowse link
G WDR72 WD repeat domain 72 acts_upstream_of_or_within ISO (PMID:26247047) MGI PMID:26247047 NCBI chr15:32,449,840...32,695,815
Ensembl chr15:50,775,112...51,023,853 		JBrowse link
basement membrane disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CMA1 chymase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:5,277,269...5,280,335
Ensembl chr14:23,400,345...23,403,548 		JBrowse link
G CTSS cathepsin S involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:126,084,249...126,118,221
Ensembl chr 1:129,733,996...129,768,318 		JBrowse link
G HPN hepsin involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:31,985,761...32,012,841
Ensembl chr19:40,725,319...40,750,628 		JBrowse link
biofilm matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSG cathepsin G involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:5,342,517...5,345,218
Ensembl chr14:23,466,265...23,468,960 		JBrowse link
negative regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST3 cystatin C involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:23,583,043...23,587,399
Ensembl chr20:23,935,942...23,940,425 		JBrowse link
G DPP4 dipeptidyl peptidase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:49,285,685...49,368,056
Ensembl chr2B:166,654,659...166,736,588 		JBrowse link
G FAP fibroblast activation protein alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr2B:49,464,199...49,537,284
Ensembl chr2B:166,832,963...166,904,950 		JBrowse link
positive regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CARMIL2 capping protein regulator and myosin 1 linker 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:47,989,040...48,001,455
Ensembl chr16:67,378,353...67,390,709 		JBrowse link
G CLASP1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:24859005) UniProt PMID:24859005 NCBI chr2B:8,265,626...8,574,282
Ensembl chr2B:121,840,484...122,102,793 		JBrowse link
G CLASP2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) UniProt PMID:24859005 NCBI chr 3:33,418,300...33,640,185
Ensembl chr 3:33,721,153...33,938,560 		JBrowse link
G DDR2 discoidin domain receptor tyrosine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:138,048,730...138,200,426
Ensembl chr 1:141,932,158...141,990,766 		JBrowse link
G FSCN1 fascin actin-bundling protein 1 involved_in ISO (PMID:20137952) UniProt PMID:20137952 NCBI chr 7:5,848,902...5,862,756 JBrowse link
G IL6 interleukin 6 involved_in ISO (PMID:26587789) ARUK-UCL PMID:26587789 NCBI chr 7:23,415,922...23,420,767 JBrowse link
G MELTF melanotransferrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:194,345,474...194,373,690
Ensembl chr 3:204,262,182...204,310,710 		JBrowse link
G PDPN podoplanin involved_in ISO (PMID:25486435) UniProt PMID:25486435 NCBI chr 1:12,728,569...12,759,781
Ensembl chr 1:13,728,233...13,759,584 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 acts_upstream_of ISO (PMID:23820254) BHF-UCL PMID:23820254 NCBI chr17:14,928,689...15,003,644
Ensembl chr17:15,152,358...15,227,067 		JBrowse link
G TGFB2 transforming growth factor beta 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:193,907,398...194,005,800
Ensembl chr 1:198,758,751...198,859,041 		JBrowse link
regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDR1 discoidin domain receptor tyrosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:30,625,871...30,645,066
Ensembl chr 6:31,496,047...31,513,455 		JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor ISO RGD PMID:16738537 RGD:2313717 NCBI chr11:123,272,111...123,400,413
Ensembl chr11:127,174,721...127,288,673 		JBrowse link
G FGFR4 fibroblast growth factor receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:172,386,443...172,400,271
Ensembl chr 5:179,454,995...179,467,605 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19315
    cellular process 18867
      cellular component organization or biogenesis 8578
        cellular component organization 8372
          cellular component disassembly 437
            extracellular matrix disassembly 39
              basement membrane disassembly + 3
              biofilm matrix disassembly 1
              negative regulation of extracellular matrix disassembly 3
              positive regulation of extracellular matrix disassembly 10
              regulation of extracellular matrix disassembly + 16
Path 2
Term Annotations click to browse term
  biological_process 19315
    cellular process 18867
      cellular component organization or biogenesis 8578
        cellular component organization 8372
          extracellular structure organization 319
            extracellular matrix organization 318
              extracellular matrix disassembly 39
                basement membrane disassembly + 3
                biofilm matrix disassembly 1
                negative regulation of extracellular matrix disassembly 3
                positive regulation of extracellular matrix disassembly 10
                regulation of extracellular matrix disassembly + 16
paths to the root