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ONTOLOGY REPORT - ANNOTATIONS


Term:extracellular matrix disassembly
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Accession:GO:0022617 term browser browse the term
Definition:A process that results in the breakdown of the extracellular matrix.



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extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 involved_in ISO (MGI:6508502|PMID:23233679) RGD PMID:23233679 MGI:6508502 NCBI chr 8:29,307,864...29,331,249
Ensembl chr 8:29,307,865...29,331,249
JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 involved_in ISO (MGI:6508502|PMID:23233679) RGD PMID:23233679 MGI:6508502 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
JBrowse link
G Capg capping actin protein, gelsolin like NOT|involved_in ISO (PMID:24236012) RGD PMID:24236012 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Cma1 chymase 1 involved_in ISO (PMID:27068509) RGD PMID:27068509 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Eng endoglin involved_in ISO (PMID:18223685) RGD PMID:18223685 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
JBrowse link
G Exoc8 exocyst complex component 8 involved_in ISO (PMID:24344185) RGD PMID:24344185 NCBI chr19:52,855,010...52,857,499
Ensembl chr19:52,852,578...52,857,491
JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:21119006) RGD PMID:21119006 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Gsn gelsolin NOT|involved_in ISO (PMID:24236012) RGD PMID:24236012 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Kif9 kinesin family member 9 involved_in ISO (PMID:21119006) RGD PMID:21119006 NCBI chr 8:110,459,467...110,504,492
Ensembl chr 8:110,459,383...110,505,252
JBrowse link
G Klk4 kallikrein-related peptidase 4 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:4355346 (MGI:5502300|PMID:22243248)
RGD PMID:22243248 PMID:21873635 MGI:5502300, RGD:13792537 NCBI chr 1:94,344,608...94,348,979
Ensembl chr 1:94,344,195...94,349,424
JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666
JBrowse link
G Lamc1 laminin subunit gamma 1 involved_in ISO (PMID:15159456) RGD PMID:15159456 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 involved_in ISO (PMID:24236012) RGD PMID:24236012 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
JBrowse link
G Mmp13 matrix metallopeptidase 13 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:3771509|PMID:17987127)
(PMID:8576151), (PMID:9065415)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:8576151 PMID:9065415 PMID:17987127 GO_REF:0000024 GO_REF:0000107 MGI:3771509 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
JBrowse link
G Mmp20 matrix metallopeptidase 20 acts_upstream_of_or_within ISO MGI:2447874 (MGI:5502300|PMID:22243248) RGD PMID:22243248 MGI:5502300 NCBI chr 8:4,789,415...4,830,035
Ensembl chr 8:4,789,415...4,830,035
JBrowse link
G Noxo1 NADPH oxidase organizer 1 involved_in ISO (PMID:19755710) RGD PMID:19755710 NCBI chr10:13,721,473...13,726,061
Ensembl chr10:13,721,473...13,726,061
JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 acts_upstream_of_or_within ISO MGI:3665440|MGI:6363079 (MGI:6277636|PMID:30659184) RGD PMID:30659184 MGI:6277636 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919
JBrowse link
G Plg plasminogen involved_in ISO (PMID:14699093) RGD PMID:14699093 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Sh3pxd2b SH3 and PX domains 2B involved_in ISO (PMID:19755710) RGD PMID:19755710 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170
JBrowse link
G Tpsab1 tryptase alpha/beta 1 involved_in ISO (PMID:27068509) RGD PMID:27068509 NCBI chr10:14,360,396...14,362,811
Ensembl chr10:14,360,396...14,362,811
JBrowse link
G Washc1 WASH complex subunit 1 involved_in ISO (PMID:24344185) RGD PMID:24344185 NCBI chr 9:105,722,779...105,830,836
Ensembl chr 9:105,722,899...105,733,009
JBrowse link
G Wdr72 WD repeat domain 72 acts_upstream_of_or_within ISO MGI:5913851 (MGI:5906533|PMID:26247047) RGD PMID:26247047 MGI:5906533 NCBI chr 8:74,838,338...75,020,938
Ensembl chr 8:74,838,318...75,018,229
JBrowse link
basement membrane disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cma1 chymase 1 involved_in ISO (PMID:27068509) RGD PMID:27068509 NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233
JBrowse link
G Ctss cathepsin S involved_in ISO (PMID:22952693)
(MGI:5553237|PMID:22952693)
RGD PMID:22952693 MGI:5553237 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Hpn hepsin involved_in ISO
ISS
(PMID:16908524)
GO_REF:0000024
RGD
UniProt
PMID:16908524 GO_REF:0000024 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
biofilm matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctsg cathepsin G involved_in ISO
ISS
(PMID:32995850)
GO_REF:0000024
RGD
UniProt
PMID:32995850 GO_REF:0000024 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
JBrowse link
negative regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cst3 cystatin C involved_in ISO (PMID:10545518) RGD PMID:10545518 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Dpp4 dipeptidylpeptidase 4 involved_in ISS
ISO
GO_REF:0000024
(PMID:16651416)
UniProt
RGD
PMID:16651416 GO_REF:0000024 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Fap fibroblast activation protein, alpha involved_in ISO (PMID:16651416) RGD PMID:16651416 NCBI chr 3:47,138,823...47,207,671
Ensembl chr 3:47,138,813...47,225,545
JBrowse link
G Mir98 microRNA 98 involved_in ISO (PMID:26587789) RGD PMID:26587789 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
positive regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Carmil2 capping protein regulator and myosin 1 linker 2 involved_in ISO (PMID:26466680), (PMID:26578515) RGD PMID:26466680 PMID:26578515 NCBI chr19:33,571,255...33,586,783
Ensembl chr19:33,574,257...33,586,965
JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr13:29,493,554...29,715,151
Ensembl chr13:29,493,596...29,715,146
JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 involved_in ISO (MGI:2158097|PMID:11723120) RGD PMID:11723120 MGI:2158097 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363
JBrowse link
G Fscn1 fascin actin-bundling protein 1 involved_in ISO
ISS
(PMID:20137952)
GO_REF:0000024
RGD
UniProt
PMID:20137952 GO_REF:0000024 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
JBrowse link
G Il6 interleukin 6 involved_in ISO (PMID:26587789) RGD PMID:26587789 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Meltf melanotransferrin involved_in ISO (PMID:16713448) RGD PMID:16713448 NCBI chr11:68,884,446...68,906,300
Ensembl chr11:68,884,446...68,906,300
JBrowse link
G Pdpn podoplanin involved_in ISS
IBA
ISO
GO_REF:0000024
PMID:21873635
(PMID:25486435)
UniProt
RGD
PMID:25486435 PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:5688835|PMID:21984612) RGD PMID:21984612 MGI:5688835 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
regulation of extracellular matrix disassembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddr1 discoidin domain receptor tyrosine kinase 1 involved_in ISO
IEA
ISS
(PMID:12065315)
GO_REF:0000107
(MGI:3629583|PMID:12065315)
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:12065315 GO_REF:0000024 GO_REF:0000107 MGI:3629583 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IMP RGD PMID:16738537 RGD:2313717 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 involved_in ISO
ISS
(PMID:20876804)
GO_REF:0000024
RGD
UniProt
PMID:20876804 GO_REF:0000024 NCBI chr17:9,461,541...9,476,268
Ensembl chr17:9,461,547...9,476,242
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          cellular component disassembly 472
            extracellular matrix disassembly 41
              basement membrane disassembly + 3
              biofilm matrix disassembly 1
              negative regulation of extracellular matrix disassembly 4
              positive regulation of extracellular matrix disassembly 9
              regulation of extracellular matrix disassembly + 16
Path 2
Term Annotations click to browse term
  biological_process 18737
    cellular process 17432
      cellular component organization or biogenesis 6534
        cellular component organization 6309
          extracellular structure organization 321
            extracellular matrix organization 320
              extracellular matrix disassembly 41
                basement membrane disassembly + 3
                biofilm matrix disassembly 1
                negative regulation of extracellular matrix disassembly 4
                positive regulation of extracellular matrix disassembly 9
                regulation of extracellular matrix disassembly + 16
paths to the root