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ONTOLOGY REPORT - ANNOTATIONS

Term:digestive system process
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Accession:GO:0022600 term browser browse the term
Definition:A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.


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digestive system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23975432) Ensembl
MGI		 PMID:23975432 GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043 		JBrowse link
defecation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LIPA lipase A, lysosomal acid type acts_upstream_of_or_within ISO (PMID:25147230) MGI PMID:25147230 NCBI chr26:38,892,771...38,918,441
Ensembl chr26:38,893,337...38,918,436 		JBrowse link
G LOC491316 midkine involved_in ISO (MGI:2178952|PMID:10096022) DFLAT PMID:10096022 MGI:2178952 NCBI chr 9:55,100,491...55,101,081 JBrowse link
gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCKAR cholecystokinin A receptor ISO RGD PMID:9773935 RGD:2313338 NCBI chr 3:84,010,700...84,019,066
Ensembl chr 3:84,010,205...84,021,293 		JBrowse link
G CCKBR cholecystokinin B receptor acts_upstream_of_or_within ISO (PMID:15476751) MGI PMID:15476751 NCBI chr21:29,602,066...29,606,343
Ensembl chr21:29,604,150...29,605,725 		JBrowse link
G CHRM5 cholinergic receptor muscarinic 5 involved_in IEA InterPro GO_REF:0000002 NCBI chr30:988,764...1,074,599
Ensembl chr30:990,208...991,806 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510 		JBrowse link
G GPR39 G protein-coupled receptor 39 acts_upstream_of ISO (PMID:17030183) MGI PMID:17030183 NCBI chr19:35,385,835...35,585,953
Ensembl chr19:35,385,829...35,586,507 		JBrowse link
G HRH2 histamine receptor H2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15476751) InterPro
MGI		 PMID:15476751 GO_REF:0000002 NCBI chr 4:37,333,843...37,407,146
Ensembl chr 4:37,275,852...37,386,072 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043 		JBrowse link
G LOC611347 uncharacterized LOC611347 ISO RGD PMID:12584108 RGD:1642125 NCBI chr13:47,865,037...48,047,697
Ensembl chr13:47,865,002...47,893,921 		JBrowse link
G SLC26A7 solute carrier family 26 member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr29:36,616,054...36,729,705
Ensembl chr29:36,615,676...36,726,803 		JBrowse link
G SLC9A4 solute carrier family 9 member A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15684419) Ensembl
MGI		 PMID:15684419 GO_REF:0000107 NCBI chr10:40,492,031...40,560,423
Ensembl chr10:40,492,613...40,560,472 		JBrowse link
G SNX10 sorting nexin 10 acts_upstream_of_or_within ISO (PMID:25811986) MGI PMID:25811986 NCBI chr14:39,567,701...39,642,475
Ensembl chr14:39,567,471...39,640,872 		JBrowse link
G TFF2 trefoil factor 2 acts_upstream_of ISO (PMID:11805131) MGI PMID:11805131 NCBI chr31:36,665,647...36,668,423
Ensembl chr31:36,665,514...36,668,440 		JBrowse link
gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:17030183) MGI PMID:17030183 NCBI chr19:35,385,835...35,585,953
Ensembl chr19:35,385,829...35,586,507 		JBrowse link
G NPPC natriuretic peptide C involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:43,714,545...43,718,969
Ensembl chr25:43,717,939...43,718,996 		JBrowse link
G NPR2 natriuretic peptide receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:52,283,680...52,339,247
Ensembl chr11:52,321,590...52,339,249 		JBrowse link
gastric motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:16012930 RGD:5131268 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142 		JBrowse link
gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HRH2 histamine receptor H2 acts_upstream_of_or_within ISO (PMID:15476751)
(PMID:10862789)		 MGI PMID:10862789 PMID:15476751 NCBI chr 4:37,333,843...37,407,146
Ensembl chr 4:37,275,852...37,386,072 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043 		JBrowse link
histamine-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HRH2 histamine receptor H2 acts_upstream_of_or_within ISO (PMID:10862789)
(PMID:15476751)		 MGI PMID:10862789 PMID:15476751 NCBI chr 4:37,333,843...37,407,146
Ensembl chr 4:37,275,852...37,386,072 		JBrowse link
intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:24839994 RGD:11073681 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G ACO1 aconitase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18177727) Ensembl
MGI		 PMID:18177727 GO_REF:0000107 NCBI chr11:49,699,072...49,758,783
Ensembl chr11:49,699,109...49,923,257 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G CELSR3 cadherin EGF LAG seven-pass G-type receptor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:40,457,430...40,495,128
Ensembl chr20:40,457,657...40,483,881 		JBrowse link
G F11R F11 receptor involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr38:21,433,819...21,456,722
Ensembl chr38:21,451,952...21,454,959 		JBrowse link
G FABP1 fatty acid binding protein 1 ISO RGD PMID:10666570 RGD:1582399 NCBI chr17:38,242,119...38,247,969
Ensembl chr17:38,242,119...38,247,962 		JBrowse link
G FABP2 fatty acid binding protein 2 ISO RGD PMID:10666570 RGD:1582399 NCBI chr32:38,244,065...38,248,093 JBrowse link
G GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19349303) Ensembl
MGI		 PMID:19349303 GO_REF:0000107 NCBI chr30:24,481,698...24,487,855
Ensembl chr30:24,484,791...24,486,110 		JBrowse link
G IREB2 iron responsive element binding protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18177727) Ensembl
MGI		 PMID:18177727 GO_REF:0000107 NCBI chr13:38,398,445...38,441,128
Ensembl chr13:38,400,591...38,441,015 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in ISO PMID:16314573 UniProt PMID:16314573 RGD:10412292 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043 		JBrowse link
G LEP leptin involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
G MOGAT2 monoacylglycerol O-acyltransferase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:14966132) Ensembl
MGI		 PMID:14966132 GO_REF:0000107 NCBI chr21:22,899,620...22,954,776
Ensembl chr21:22,899,598...22,918,523 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 acts_upstream_of_or_within ISO (PMID:15601832) MGI PMID:15601832 NCBI chr26:24,884,853...24,956,190
Ensembl chr26:24,884,129...24,958,122 		JBrowse link
G TJP2 tight junction protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:88,126,134...88,251,018
Ensembl chr 1:88,126,136...88,230,654 		JBrowse link
G VDR vitamin D receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:11687634) Ensembl
MGI		 PMID:11687634 GO_REF:0000107 NCBI chr27:6,852,915...6,909,466
Ensembl chr27:6,852,723...6,909,470 		JBrowse link
intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:20,299,808...20,375,856
Ensembl chr18:20,339,050...20,372,639 		JBrowse link
G CEL carboxyl ester lipase involved_in ISO (PMID:12031288) UniProt PMID:12031288 NCBI chr 9:51,337,205...51,345,284
Ensembl chr 9:51,337,187...51,362,422 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355 		JBrowse link
G LIMA1 LIM domain and actin binding 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:4,473,151...4,561,916
Ensembl chr27:4,473,179...4,561,574 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:64,764,941...64,802,507
Ensembl chr 7:64,760,121...64,802,902 		JBrowse link
G NPC1L1 NPC1 like intracellular cholesterol transporter 1 involved_in IEA TreeGrafter GO_REF:0000118
G PNLIP pancreatic lipase acts_upstream_of_or_within ISO (PMID:12915407) MGI PMID:12915407 NCBI chr28:27,139,028...27,156,457
Ensembl chr28:27,139,230...27,212,178 		JBrowse link
intestinal D-glucose absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EZR ezrin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:48,160,206...48,210,036
Ensembl chr 1:48,160,206...48,210,036 		JBrowse link
G PLS1 plastin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:38,243,631...38,347,195
Ensembl chr23:38,243,024...38,347,202 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 involved_in ISO (MGI:5433249|PMID:22124465) UniProt PMID:22124465 MGI:5433249 NCBI chr26:24,884,853...24,956,190
Ensembl chr26:24,884,129...24,958,122 		JBrowse link
G VIL1 villin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr37:25,065,887...25,090,238
Ensembl chr37:25,065,180...25,090,705 		JBrowse link
intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10RA interleukin 10 receptor subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:15,675,775...15,688,935
Ensembl chr 5:15,677,547...15,682,163 		JBrowse link
G IL17A interleukin 17A involved_in ISO (MGI:5788042|PMID:26431948) UniProt PMID:26431948 MGI:5788042 NCBI chr12:19,854,129...19,862,521
Ensembl chr12:19,854,129...19,862,513 		JBrowse link
G INAVA innate immunity activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:2,264,120...2,284,196 JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:17681175) UniProt
MGI
Ensembl		 PMID:17681175 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G TLR4 toll like receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:71,356,390...71,367,166
Ensembl chr11:71,356,390...71,367,165 		JBrowse link
G ZNF830 zinc finger protein 830 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23213458) Ensembl
MGI		 PMID:23213458 GO_REF:0000107 NCBI chr 9:38,382,508...38,384,060
Ensembl chr 9:38,382,900...38,384,015 		JBrowse link
intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FABP2 fatty acid binding protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:38,244,065...38,248,093 JBrowse link
G SCARB1 scavenger receptor class B member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:25701869) Ensembl
MGI		 PMID:25701869 GO_REF:0000107 NCBI chr26:5,035,797...5,122,383
Ensembl chr26:5,049,407...5,121,468 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:66,439,346...66,472,897
Ensembl chr11:66,439,346...66,472,897 		JBrowse link
large intestinal transit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HTR4 5-hydroxytryptamine receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:60,224,534...60,359,244
Ensembl chr 4:60,185,056...60,353,439 		JBrowse link
maintenance of gastrointestinal epithelium term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRACD capping protein inhibiting regulator of actin dynamics involved_in IEA TreeGrafter GO_REF:0000118
G HTR4 5-hydroxytryptamine receptor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:60,224,534...60,359,244
Ensembl chr 4:60,185,056...60,353,439 		JBrowse link
G MUC13 mucin 13, cell surface associated involved_in ISO (PMID:17058067) UniProt PMID:17058067 NCBI chr33:27,926,395...27,951,690
Ensembl chr33:27,926,442...27,958,778 		JBrowse link
G MUC2 mucin 2, oligomeric mucus/gel-forming involved_in ISO (PMID:17058067)
(MGI:6471838|PMID:33093110), (PMID:35337837)		 UniProt PMID:17058067 PMID:33093110 PMID:35337837 MGI:6471838 NCBI chr18:45,416,347...45,438,226 JBrowse link
G MUC4 mucin 4, cell surface associated involved_in ISO (PMID:17058067) UniProt PMID:17058067 NCBI chr33:29,061,372...29,084,938
Ensembl chr33:29,063,096...29,111,802 		JBrowse link
G NOD2 nucleotide binding oligomerization domain containing 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:64,636,850...64,667,232
Ensembl chr 2:64,635,519...64,667,232 		JBrowse link
G PAICS phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr13:48,296,232...48,682,650 JBrowse link
G PBLD phenazine biosynthesis like protein domain containing involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:19,514,256...19,558,515
Ensembl chr 4:19,515,050...19,558,335 		JBrowse link
G RBP4 retinol binding protein 4 involved_in ISO (PMID:10944490) BHF-UCL PMID:10944490 NCBI chr28:7,822,936...7,830,735
Ensembl chr28:7,822,944...7,830,750 		JBrowse link
G STRAP serine/threonine kinase receptor associated protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:30,800,853...30,817,578
Ensembl chr27:30,675,247...30,817,388 		JBrowse link
G TFF1 trefoil factor 1 involved_in ISO
IBA
IEA		 RGD
GO_Central
TreeGrafter		 PMID:8836141 GO_REF:0000033 GO_REF:0000118 RGD:625375 NCBI chr31:36,681,478...36,684,571
Ensembl chr31:36,681,357...36,695,665 		JBrowse link
G TFF2 trefoil factor 2 involved_in IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr31:36,665,647...36,668,423
Ensembl chr31:36,665,514...36,668,440 		JBrowse link
G TFF3 trefoil factor 3 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr31:36,638,762...36,641,696 JBrowse link
G TLR9 toll like receptor 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:37,529,322...37,547,117
Ensembl chr20:37,542,340...37,547,114
Ensembl chr20:37,542,340...37,547,114 		JBrowse link
G VSIG1 V-set and immunoglobulin domain containing 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21991385) InterPro
MGI
TreeGrafter		 PMID:21991385 GO_REF:0000002 GO_REF:0000118 NCBI chr  X:81,574,202...81,618,242
Ensembl chr  X:81,574,025...81,616,879 		JBrowse link
mastication term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COMT catechol-O-methyltransferase acts_upstream_of_or_within ISO (PMID:17707921) MGI PMID:17707921 NCBI chr26:29,359,930...29,381,854
Ensembl chr26:29,360,356...29,366,008 		JBrowse link
G NEUROG1 neurogenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,563,128...23,564,819
Ensembl chr11:23,563,803...23,564,543 		JBrowse link
G TIFAB TIFA inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,492,317...23,495,825
Ensembl chr11:23,492,867...23,493,352 		JBrowse link
negative regulation of defecation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:21277852 RGD:5491003 NCBI chr14:43,366,849...43,414,398
Ensembl chr14:43,368,340...43,415,142 		JBrowse link
G NPSR1 neuropeptide S receptor 1 ISO RGD PMID:21708257 RGD:9831204 NCBI chr14:46,465,169...46,610,256
Ensembl chr14:46,466,544...46,609,477 		JBrowse link
negative regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:17030183) MGI PMID:17030183 NCBI chr19:35,385,835...35,585,953
Ensembl chr19:35,385,829...35,586,507 		JBrowse link
G LOC611347 uncharacterized LOC611347 involved_in ISO PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr13:47,865,037...48,047,697
Ensembl chr13:47,865,002...47,893,921 		JBrowse link
G PTGER3 prostaglandin E receptor 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G TFF2 trefoil factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:11805131) TreeGrafter
MGI
GO_Central		 PMID:11805131 GO_REF:0000033 GO_REF:0000118 NCBI chr31:36,665,647...36,668,423
Ensembl chr31:36,665,514...36,668,440 		JBrowse link
negative regulation of gastric emptying term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC611347 uncharacterized LOC611347 involved_in ISO PMID:12584108 UniProt PMID:12584108 RGD:1642125 NCBI chr13:47,865,037...48,047,697
Ensembl chr13:47,865,002...47,893,921 		JBrowse link
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:15961884 RGD:10043339 NCBI chr 6:74,932,789...74,986,573 JBrowse link
G SCT secretin involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:11123201 GO_REF:0000118 RGD:9590235
negative regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG2 ATP binding cassette subfamily G member 2 ISO RGD PMID:23333829 RGD:11099975 NCBI chr32:11,443,778...11,517,674
Ensembl chr32:11,443,780...11,517,674 		JBrowse link
G HAMP hepcidin antimicrobial peptide involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:117,305,531...117,306,587
Ensembl chr 1:117,305,411...117,306,619 		JBrowse link
G ISX intestine specific homeobox acts_upstream_of_or_within ISO (PMID:25701869) MGI PMID:25701869 NCBI chr10:28,993,515...29,011,736
Ensembl chr10:28,993,795...29,011,640 		JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:46,261,747...46,300,084
Ensembl chr10:46,271,772...46,299,773 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:46,300,142...46,319,592
Ensembl chr10:46,300,165...46,319,229 		JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:46,261,747...46,300,084
Ensembl chr10:46,271,772...46,299,773 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:46,300,142...46,319,592
Ensembl chr10:46,300,165...46,319,229 		JBrowse link
negative regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MADD MAP kinase activating death domain ISO RGD PMID:23702376 RGD:9588639 NCBI chr18:42,290,226...42,332,237
Ensembl chr18:42,290,754...42,328,586 		JBrowse link
negative regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H3 nuclear receptor subfamily 1 group H member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236 		JBrowse link
G STK39 serine/threonine kinase 39 involved_in IEA Ensembl GO_REF:0000107 NCBI chr36:12,866,867...13,118,736
Ensembl chr36:12,867,188...13,183,160 		JBrowse link
G VPS25 vacuolar protein sorting 25 homolog acts_upstream_of_or_within ISO (PMID:21317537) MGI PMID:21317537 NCBI chr 9:20,242,230...20,247,396 JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21317537) Ensembl
MGI		 PMID:21317537 GO_REF:0000107 NCBI chr27:42,764,184...42,914,591
Ensembl chr27:42,765,181...42,912,806 		JBrowse link
G WNK3 WNK lysine deficient protein kinase 3 involved_in ISO (MGI:5002793|PMID:21317537) UniProt PMID:21317537 MGI:5002793 NCBI chr  X:45,951,049...46,111,643
Ensembl chr  X:45,571,840...46,081,994 		JBrowse link
G WNK4 WNK lysine deficient protein kinase 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,224,726...20,241,214
Ensembl chr 9:20,157,410...20,241,376 		JBrowse link
negative regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROG1 neurogenin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,563,128...23,564,819
Ensembl chr11:23,563,803...23,564,543 		JBrowse link
G TIFAB TIFA inhibitor involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:23,492,317...23,495,825
Ensembl chr11:23,492,867...23,493,352 		JBrowse link
pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 involved_in ISO (PMID:12801959) UniProt PMID:12801959 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720 		JBrowse link
G AQP5 aquaporin 5 involved_in ISO (PMID:12801959) UniProt PMID:12801959 NCBI chr27:4,735,313...4,742,975
Ensembl chr27:4,735,538...4,737,650 		JBrowse link
G CEL carboxyl ester lipase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:51,337,205...51,345,284
Ensembl chr 9:51,337,187...51,362,422 		JBrowse link
G COPA COPI coat complex subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:1429581) Ensembl
MGI		 PMID:1429581 GO_REF:0000107 NCBI chr38:21,892,995...21,936,076
Ensembl chr38:21,892,993...21,936,458 		JBrowse link
positive regulation of digestive system process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRH corticotropin releasing hormone ISO gut paracellular permeability RGD PMID:17234701 RGD:5491013 NCBI chr29:15,831,944...15,840,560
Ensembl chr29:15,831,944...15,834,384 		JBrowse link
positive regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G OXT oxytocin/neurophysin I prepropeptide ISO RGD PMID:19258489 RGD:2304084 NCBI chr24:18,193,381...18,194,232
Ensembl chr24:18,193,339...18,194,170 		JBrowse link
G PAWR pro-apoptotic WT1 regulator ISO RGD PMID:14724155 RGD:9835340 NCBI chr15:22,114,014...22,159,287 JBrowse link
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAT2 acetyl-CoA acetyltransferase 2 involved_in ISO (MGI:5302163|PMID:22045928) CACAO PMID:22045928 MGI:5302163 NCBI chr 1:49,011,665...49,029,368
Ensembl chr 1:49,011,706...49,029,327 		JBrowse link
G CYP8B1 cytochrome P450 family 8 subfamily B member 1 involved_in ISO (MGI:3588413|PMID:12393855) UniProt PMID:12393855 MGI:3588413 NCBI chr23:11,965,685...11,968,994
Ensembl chr23:11,967,341...11,968,846 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:5574251|PMID:24650549) UniProt PMID:24650549 MGI:5574251 NCBI chr 9:1,887,093...1,894,728
Ensembl chr 9:1,887,201...1,897,473 		JBrowse link
G LPCAT3 lysophosphatidylcholine acyltransferase 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr27:38,028,438...38,068,854
Ensembl chr27:38,028,120...38,068,502 		JBrowse link
positive regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC22A5 solute carrier family 22 member 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:20,659,023...20,686,359
Ensembl chr11:20,598,888...20,683,087 		JBrowse link
positive regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRAP1 proline rich acidic protein 1 involved_in ISO (MGI:6706092|PMID:33168624) UniProt PMID:33168624 MGI:6706092 NCBI chr28:40,927,744...40,931,355 JBrowse link
positive regulation of pancreatic amylase secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G VAMP8 vesicle associated membrane protein 8 acts_upstream_of_or_within ISO (PMID:18535671) MGI PMID:18535671 NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739 		JBrowse link
positive regulation of pancreatic juice secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPR3 natriuretic peptide receptor 3 ISO RGD PMID:12829435 RGD:1581460 NCBI chr 4:74,794,553...74,863,344
Ensembl chr 4:74,799,857...74,862,969 		JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:106,332,691...106,339,168
Ensembl chr 1:106,332,798...106,339,135 		JBrowse link
G SCT secretin involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:11123201 GO_REF:0000118 RGD:9590235
G SPINK1 serine peptidase inhibitor Kazal type 1 ISO RGD PMID:2755938 RGD:10044250 NCBI chr 2:42,112,015...42,120,738
Ensembl chr 2:42,112,016...42,120,706 		JBrowse link
positive regulation of pancreatic trypsinogen secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MMP13 matrix metallopeptidase 13 ISO RGD PMID:12771515 RGD:724699 NCBI chr 5:28,793,568...28,864,832
Ensembl chr 5:28,850,522...28,864,121 		JBrowse link
positive regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 involved_in ISS UniProt GO_REF:0000024 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720 		JBrowse link
G NEGR1 neuronal growth regulator 1 acts_upstream_of_or_within ISO (PMID:37216094) MGI PMID:37216094 NCBI chr 6:73,823,686...74,637,906
Ensembl chr 6:73,823,826...74,634,764 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:22,688,141...22,996,693
Ensembl chr32:22,688,143...22,996,688 		JBrowse link
G TAC4 tachykinin precursor 4 acts_upstream_of_or_within ISO (PMID:11062498) MGI PMID:11062498 NCBI chr 9:25,886,197...25,890,083
Ensembl chr 9:25,882,360...25,889,956 		JBrowse link
positive regulation of small intestinal transit term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:21874246 RGD:12910732 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:15890336 PMID:21874246 RGD:12907565 RGD:12910732 NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312 		JBrowse link
regulation of gastric acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HIP1R huntingtin interacting protein 1 related involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:6,623,583...6,639,107
Ensembl chr26:6,624,791...6,637,659 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:46,554,390...46,830,533
Ensembl chr18:46,518,908...46,830,043 		JBrowse link
regulation of gastric motility term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:23525979 RGD:12907567 NCBI chr20:8,092,921...8,097,512
Ensembl chr20:8,092,957...8,097,510 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO RGD PMID:23525979 RGD:12907567 NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312 		JBrowse link
regulation of hindgut contraction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GHSR growth hormone secretagogue receptor ISO RGD PMID:16873401 RGD:1625276 NCBI chr34:36,691,132...36,694,304
Ensembl chr34:36,690,224...36,694,312 		JBrowse link
regulation of intestinal absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO RGD PMID:22049154 RGD:8657330 NCBI chr14:13,644,891...13,852,829
Ensembl chr14:13,542,647...13,742,727 		JBrowse link
G EPB41 erythrocyte membrane protein band 4.1 involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:71,474,916...71,673,052
Ensembl chr 2:71,474,954...71,584,266 		JBrowse link
regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA1 apolipoprotein A1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10073953) Ensembl
MGI
TreeGrafter		 PMID:10073953 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:16,740,071...16,742,081
Ensembl chr 5:16,740,130...16,741,943 		JBrowse link
G APOA2 apolipoprotein A2 acts_upstream_of_or_within ISO (PMID:8962133) MGI PMID:8962133 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887 		JBrowse link
G APOA4 apolipoprotein A4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9323588) Ensembl
MGI
TreeGrafter		 PMID:9323588 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:16,751,588...16,754,215
Ensembl chr 5:16,751,799...16,754,837 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12114517) Ensembl
MGI		 PMID:12114517 GO_REF:0000107 NCBI chr14:8,115,396...8,130,946
Ensembl chr14:8,116,122...8,131,395 		JBrowse link
regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEUROD1 neuronal differentiation 1 involved_in ISO (MGI:5009210|PMID:9512516) UniProt PMID:9512516 MGI:5009210 NCBI chr36:24,853,591...24,857,886 JBrowse link
regulation of intestinal lipid absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DGAT1 diacylglycerol O-acyltransferase 1 ISO RGD PMID:18768481 RGD:10400848 NCBI chr13:37,745,395...37,761,337
Ensembl chr13:37,741,706...37,756,916 		JBrowse link
G ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 involved_in ISO (MGI:4947032|PMID:21177474) UniProt PMID:21177474 MGI:4947032 NCBI chr 9:1,887,093...1,894,728
Ensembl chr 9:1,887,201...1,897,473 		JBrowse link
regulation of saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FGF10 fibroblast growth factor 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:65,851,130...65,930,944
Ensembl chr 4:65,851,069...65,928,192 		JBrowse link
G OPRK1 opioid receptor kappa 1 involved_in ISO (MGI:1197118|PMID:9463367) UniProt PMID:9463367 MGI:1197118 NCBI chr29:5,022,270...5,054,223
Ensembl chr29:5,025,786...5,051,919 		JBrowse link
saliva secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP5 aquaporin 5 acts_upstream_of_or_within ISO (PMID:10400615), (PMID:10795927), (PMID:15647389) MGI PMID:10400615 PMID:10795927 PMID:15647389 NCBI chr27:4,735,313...4,742,975
Ensembl chr27:4,735,538...4,737,650 		JBrowse link
G CHRM1 cholinergic receptor muscarinic 1 involved_in IEA InterPro GO_REF:0000002 NCBI chr18:53,783,938...53,797,750
Ensembl chr18:53,795,326...53,796,708 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:10944224) InterPro
MGI		 PMID:10944224 GO_REF:0000002 NCBI chr 4:504,663...999,550
Ensembl chr 4:506,990...520,613 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 involved_in
acts_upstream_of_or_within		 ISA
ISO		 (PMID:8973172)
(PMID:16873365)		 AgBase
MGI		 PMID:8973172 PMID:16873365 NCBI chr 4:26,844,250...27,338,271
Ensembl chr 4:26,844,250...27,555,776 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16873365) Ensembl
MGI		 PMID:16873365 GO_REF:0000107 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701 		JBrowse link
G SLC4A9 solute carrier family 4 member 9 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:35,575,316...35,589,878
Ensembl chr 2:35,576,550...35,587,980 		JBrowse link
G TRPC1 transient receptor potential cation channel subfamily C member 1 acts_upstream_of_or_within ISO (PMID:17956991) MGI PMID:17956991 NCBI chr23:38,350,066...38,416,086
Ensembl chr23:38,350,278...38,414,464 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17917
    multicellular organismal process 8083
      digestion 131
        digestive system process 116
          defecation + 4
          gastric acid secretion + 15
          gastric motility + 7
          hindgut contraction + 3
          intestinal absorption + 41
          intestinal motility + 3
          maintenance of gastrointestinal epithelium + 23
          mastication 3
          negative regulation of digestive system process + 20
          pancreatic juice secretion + 17
          positive regulation of digestive system process + 19
          regulation of digestive system process + 50
          rumination 0
          saliva secretion + 15
paths to the root