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ONTOLOGY REPORT - ANNOTATIONS
Term:digestive system process
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Accession:GO:0022600 term browser browse the term
Definition:A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.

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gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atp4a ATPase H+/K+ transporting subunit alpha JBrowse link 1 89,162,700 89,175,504 RGD:631722
G Cartpt CART prepropeptide JBrowse link 2 30,125,249 30,127,408 RGD:1302914
G Cckar cholecystokinin A receptor JBrowse link 14 59,610,939 59,619,786 RGD:2313338
G Cckbr cholecystokinin B receptor JBrowse link 1 170,262,218 170,272,298 RGD:1624291
RGD:1600115
G Chrm5 cholinergic receptor, muscarinic 5 JBrowse link 3 103,966,451 104,018,815 RGD:1600115
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:8553549
RGD:13792537
G Hrh2 histamine receptor H 2 JBrowse link 17 10,912,959 10,931,389 RGD:1624291
G Nmu neuromedin U JBrowse link 14 34,353,683 34,381,968 RGD:1642125
G Slc26a7 solute carrier family 26 member 7 JBrowse link 5 27,986,656 28,131,294 RGD:1624291
G Slc9a4 solute carrier family 9 member A4 JBrowse link 9 47,281,821 47,334,755 RGD:1624291
RGD:1600115
G Snx10 sorting nexin 10 JBrowse link 4 81,311,490 81,375,248 RGD:1624291
gastric emptying term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:6907451
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12907565
G Gpr39 G protein-coupled receptor 39 JBrowse link 13 42,008,642 42,220,737 RGD:1624291
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:5490560
gastric motility term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crhr2 corticotropin releasing hormone receptor 2 JBrowse link 4 85,286,371 85,329,374 RGD:5131268
gastrin-induced gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrh2 histamine receptor H 2 JBrowse link 17 10,912,959 10,931,389 RGD:1624291
RGD:1600115
histamine-induced gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hrh2 histamine receptor H 2 JBrowse link 17 10,912,959 10,931,389 RGD:1624291
RGD:1600115
intestinal absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:11073681
G Aco1 aconitase 1 JBrowse link 5 56,425,076 56,481,218 RGD:1624291
RGD:1600115
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
RGD:1600115
G F11r F11 receptor JBrowse link 13 89,826,272 89,850,151 RGD:1624291
RGD:13792537
G Fabp1 fatty acid binding protein 1 JBrowse link 4 99,063,181 99,066,957 RGD:1582399
G Fabp2 fatty acid binding protein 2 JBrowse link 2 227,080,912 227,083,654 RGD:1582399
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link 8 76,449,078 76,459,431 RGD:1624291
G Ireb2 iron responsive element binding protein 2 JBrowse link 8 59,450,974 59,503,634 RGD:1624291
RGD:1600115
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:10412292
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
RGD:1600115
G Mogat2 monoacylglycerol O-acyltransferase 2 JBrowse link 1 164,181,762 164,205,222 RGD:1624291
G Scarb1 scavenger receptor class B, member 1 JBrowse link 12 36,694,952 36,761,445 RGD:1624291
G Slc26a6 solute carrier family 26 member 6 JBrowse link 8 117,648,792 117,659,376 RGD:1624291
G Slc5a1 solute carrier family 5 member 1 JBrowse link 14 82,910,448 82,975,303 RGD:1624259
RGD:1624291
G Slco1a5 solute carrier organic anion transporter family, member 1A5 JBrowse link 4 176,445,856 176,528,117 RGD:2303071
G Tjp2 tight junction protein 2 JBrowse link 1 241,945,816 242,084,044 RGD:1624291
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:1624291
RGD:1600115
intestinal cholesterol absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:1624291
RGD:1600115
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:1624291
RGD:1600115
G Lima1 LIM domain and actin binding 1 JBrowse link 7 141,428,113 141,528,447 RGD:1624291
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 JBrowse link 14 86,345,946 86,560,694 RGD:1624291
G Pnlip pancreatic lipase JBrowse link 1 279,798,187 279,811,372 RGD:1624291
RGD:1600115
intestinal D-glucose absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ezr ezrin JBrowse link 1 47,287,872 47,331,412 RGD:1624291
G Pls1 plastin 1 JBrowse link 8 103,557,361 103,659,625 RGD:1624291
G Slc5a1 solute carrier family 5 member 1 JBrowse link 14 82,910,448 82,975,303 RGD:1624261
G Vil1 villin 1 JBrowse link 9 81,689,802 81,717,623 RGD:1624291
intestinal epithelial structure maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:1624291
G Inava innate immunity activator JBrowse link 13 53,088,438 53,108,713 RGD:1624291
G Sox9 SRY-box transcription factor 9 JBrowse link 10 101,288,528 101,294,030 RGD:1624291
RGD:1600115
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:1624291
RGD:1600115
G Zfp830 zinc finger protein 830 JBrowse link 10 70,118,250 70,119,714 RGD:1624291
intestinal lipid absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fabp2 fatty acid binding protein 2 JBrowse link 2 227,080,912 227,083,654 RGD:1600115
RGD:1624291
G Ugcg UDP-glucose ceramide glucosyltransferase JBrowse link 5 76,376,722 76,419,564 RGD:1624291
RGD:1600115
maintenance of gastrointestinal epithelium term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cracd capping protein inhibiting regulator of actin dynamics JBrowse link 14 33,649,989 33,783,794 RGD:1624291
G Muc13 mucin 13, cell surface associated JBrowse link 11 70,185,757 70,223,012 RGD:1624291
G Muc2 mucin 2, oligomeric mucus/gel-forming JBrowse link 1 214,663,929 214,693,197 RGD:1624291
G Muc4 mucin 4, cell surface associated JBrowse link 11 71,242,973 71,285,217 RGD:1624291
G Muc6 mucin 6, oligomeric mucus/gel-forming JBrowse link 1 214,608,453 214,630,524 RGD:1600115
G Nod2 nucleotide-binding oligomerization domain containing 2 JBrowse link 19 19,342,061 19,389,366 RGD:1624291
G Pbld1 phenazine biosynthesis-like protein domain containing 1 JBrowse link 20 27,103,300 27,118,650 RGD:1624291
G Rbp4 retinol binding protein 4 JBrowse link 1 256,806,476 256,813,678 RGD:1624291
G Strap serine/threonine kinase receptor associated protein JBrowse link 4 171,730,629 171,744,877 RGD:1624291
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:625375
RGD:13792537
G Tff2 trefoil factor 2 JBrowse link 20 9,872,669 9,876,008 RGD:13792537
G Tff3 trefoil factor 3 JBrowse link 20 9,850,800 9,855,481 RGD:13792537
G Tlr9 toll-like receptor 9 JBrowse link 8 114,916,122 114,920,171 RGD:1624291
G Vsig1 V-set and immunoglobulin domain containing 1 JBrowse link X 112,268,786 112,303,849 RGD:1624291
RGD:13792537
RGD:1600115
mastication term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neurog1 neurogenin 1 JBrowse link 17 9,154,656 9,156,175 RGD:1624291
G Tifab TIFA inhibitor JBrowse link 17 9,234,948 9,239,266 RGD:1624291
negative regulation of gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gpr39 G protein-coupled receptor 39 JBrowse link 13 42,008,642 42,220,737 RGD:1624291
G Nmu neuromedin U JBrowse link 14 34,353,683 34,381,968 RGD:1642125
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:2304192
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:2304192
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043339
RGD:13792537
G Tff2 trefoil factor 2 JBrowse link 20 9,872,669 9,876,008 RGD:1624291
RGD:13792537
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:5490560
negative regulation of gastric emptying term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nmu neuromedin U JBrowse link 14 34,353,683 34,381,968 RGD:1642125
G Ptger1 prostaglandin E receptor 1 JBrowse link 19 24,799,422 24,803,373 RGD:10043357
negative regulation of gastrin-induced gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043339
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:9590235
RGD:13792537
negative regulation of intestinal absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:11099975
G Hamp hepcidin antimicrobial peptide JBrowse link 1 89,368,021 89,369,960 RGD:1624291
G Isx intestine-specific homeobox JBrowse link 19 14,198,899 14,219,269 RGD:1624291
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 6 7,935,771 7,961,207 RGD:1624291
G Abcg8 ATP binding cassette subfamily G member 8 JBrowse link 6 7,961,413 7,980,708 RGD:1624291
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg5 ATP binding cassette subfamily G member 5 JBrowse link 6 7,935,771 7,961,207 RGD:1624291
G Abcg8 ATP binding cassette subfamily G member 8 JBrowse link 6 7,961,413 7,980,708 RGD:1624291
negative regulation of pancreatic amylase secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Madd MAP-kinase activating death domain JBrowse link 3 79,960,301 80,003,023 RGD:9588639
negative regulation of pancreatic juice secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:1624291
RGD:1600115
G Stk39 serine threonine kinase 39 JBrowse link 3 54,359,449 54,625,702 RGD:1624291
G Wnk1 WNK lysine deficient protein kinase 1 JBrowse link 4 152,452,211 152,578,469 RGD:1624291
G Wnk3 WNK lysine deficient protein kinase 3 JBrowse link X 20,316,081 20,459,245 RGD:1624291
G Wnk4 WNK lysine deficient protein kinase 4 JBrowse link 10 89,181,139 89,198,213 RGD:1624291
negative regulation of saliva secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neurog1 neurogenin 1 JBrowse link 17 9,154,656 9,156,175 RGD:1624291
G Tifab TIFA inhibitor JBrowse link 17 9,234,948 9,239,266 RGD:1624291
pancreatic juice secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1624291
G Aqp5 aquaporin 5 JBrowse link 7 141,249,044 141,252,576 RGD:1624291
G Cckar cholecystokinin A receptor JBrowse link 14 59,610,939 59,619,786 RGD:2313374
G Cel carboxyl ester lipase JBrowse link 3 7,134,021 7,141,522 RGD:1624291
G Copa COPI coat complex subunit alpha JBrowse link 13 90,467,285 90,508,894 RGD:1624291
G Dbi diazepam binding inhibitor, acyl-CoA binding protein JBrowse link 13 36,147,667 36,156,076 RGD:2316282
G Npr3 natriuretic peptide receptor 3 JBrowse link 2 61,883,946 61,950,291 RGD:1581460
G Ucn urocortin JBrowse link 6 26,602,144 26,602,974 RGD:1642798
positive regulation of digestive system process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crh corticotropin releasing hormone JBrowse link 2 104,459,999 104,461,863 RGD:5491013
positive regulation of gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1581605
G Oprl1 opioid related nociceptin receptor 1 JBrowse link 3 177,223,779 177,231,663 RGD:9835018
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:2317117
positive regulation of hindgut contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:2304084
G Pawr pro-apoptotic WT1 regulator JBrowse link 7 51,273,764 51,353,700 RGD:9835340
positive regulation of intestinal cholesterol absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acat2 acetyl-CoA acetyltransferase 2 JBrowse link 1 47,972,399 47,992,654 RGD:1624291
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
RGD:1624291
G Lpcat3 lysophosphatidylcholine acyltransferase 3 JBrowse link 4 157,181,722 157,222,997 RGD:1600115
RGD:1624291
positive regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:1624291
positive regulation of pancreatic amylase secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Vamp8 vesicle-associated membrane protein 8 JBrowse link 4 100,250,301 100,252,756 RGD:1624291
positive regulation of pancreatic juice secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nr1h2 nuclear receptor subfamily 1, group H, member 2 JBrowse link 1 100,554,577 100,559,896 RGD:1624291
G Sct secretin JBrowse link 1 214,264,865 214,277,437 RGD:9590235
RGD:13792537
G Spink1 serine peptidase inhibitor, Kazal type 1 JBrowse link 18 38,221,919 38,242,092 RGD:10044250
positive regulation of pancreatic trypsinogen secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:724699
positive regulation of saliva secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:5129135
G Aqp1 aquaporin 1 JBrowse link 4 85,551,503 85,563,683 RGD:1600115
RGD:1624291
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:5147474
G Tac4 tachykinin precursor 4 JBrowse link 10 83,081,168 83,089,487 RGD:1624291
G Tacr1 tachykinin receptor 1 JBrowse link 4 113,247,236 113,416,139 RGD:5147474
positive regulation of small intestinal transit term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12910732
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:12910732
RGD:12907565
regulation of digestive system process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Oxt oxytocin/neurophysin I prepropeptide JBrowse link 3 123,106,694 123,107,534 RGD:2304324
G Oxtr oxytocin receptor JBrowse link 4 144,399,326 144,417,598 RGD:2304324
regulation of gastric acid secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hip1r huntingtin interacting protein 1 related JBrowse link 12 38,024,517 38,053,184 RGD:1624291
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 JBrowse link 1 216,293,087 216,630,339 RGD:1600115
RGD:1624291
regulation of gastric motility term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12907567
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:12907567
G Tymp thymidine phosphorylase JBrowse link 7 130,342,481 130,347,845 RGD:1624291
regulation of hindgut contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:1625276
regulation of intestinal absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:8657330
G Epb41 erythrocyte membrane protein band 4.1 JBrowse link 5 150,081,727 150,243,186 RGD:1624291
regulation of intestinal cholesterol absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:1624291
RGD:13792537
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:1624291
G Apoa4 apolipoprotein A4 JBrowse link 8 50,536,983 50,539,371 RGD:1624291
RGD:13792537
G Apoa5 apolipoprotein A5 JBrowse link 8 50,559,079 50,561,720 RGD:13792537
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:1624291
regulation of intestinal epithelial structure maintenance term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Neurod1 neuronal differentiation 1 JBrowse link 3 66,414,314 66,417,617 RGD:1624291
RGD:1600115
regulation of intestinal lipid absorption term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgat1 diacylglycerol O-acyltransferase 1 JBrowse link 7 117,566,363 117,576,735 RGD:10400848
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 JBrowse link 10 108,095,131 108,099,483 RGD:1600115
RGD:1624291
regulation of saliva secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Fgf10 fibroblast growth factor 10 JBrowse link 2 51,673,480 51,747,533 RGD:1624291
G Oprk1 opioid receptor, kappa 1 JBrowse link 5 13,742,655 13,760,460 RGD:1624291
RGD:1600115
saliva secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp5 aquaporin 5 JBrowse link 7 141,249,044 141,252,576 RGD:1624291
G Chrm1 cholinergic receptor, muscarinic 1 JBrowse link 1 224,869,087 224,885,101 RGD:1600115
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:1624291
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 JBrowse link 15 344,204 1,048,849 RGD:1624291
G Kcnn4 potassium calcium-activated channel subfamily N member 4 JBrowse link 1 81,227,855 81,245,986 RGD:1624291
RGD:1600115
G Trpc1 transient receptor potential cation channel, subfamily C, member 1 JBrowse link 8 103,503,982 103,554,905 RGD:1624291
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    multicellular organismal process 8951
      digestion 136
        digestive system process 116
          gastric acid secretion + 22
          gastric motility + 9
          hindgut contraction + 3
          intestinal absorption + 39
          intestinal motility + 2
          maintenance of gastrointestinal epithelium + 21
          mastication 2
          negative regulation of digestive system process + 22
          pancreatic juice secretion + 19
          positive regulation of digestive system process + 22
          regulation of digestive system process + 55
          rumination 0
          saliva secretion + 15
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.