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ONTOLOGY REPORT - ANNOTATIONS


Term:negative adaptation of signaling pathway
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Accession:GO:0022401 term browser browse the term
Definition:The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
Synonyms:exact_synonym: negative adaptation of signal transduction pathway;   negative adaptation of signalling pathway


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desensitization of G protein-coupled receptor signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gipr gastric inhibitory polypeptide receptor JBrowse link 1 80,063,047 80,073,223 RGD:2312614
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:632163
RGD:13792694
RGD:1624291
RGD:1600115
RGD:8553863
RGD:7242040
G Grk3 G protein-coupled receptor kinase 3 JBrowse link 12 49,626,871 49,750,389 RGD:632163
RGD:5685621
RGD:5685022
G Grk4 G protein-coupled receptor kinase 4 JBrowse link 14 81,261,708 81,339,516 RGD:1598508
G Grk5 G protein-coupled receptor kinase 5 JBrowse link 1 282,265,371 282,467,842 RGD:61618
RGD:13792694
G Grk6 G protein-coupled receptor kinase 6 JBrowse link 17 9,705,917 9,721,921 RGD:1299124
RGD:7242040
G Grm5 glutamate metabotropic receptor 5 JBrowse link 1 151,207,846 151,785,038 RGD:728711
G Ly6g6e lymphocyte antigen 6 family member G6E JBrowse link 20 5,063,148 5,069,032 RGD:1624291
RGD:13792537
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:9850278
desensitization of G protein-coupled receptor signaling pathway by arrestin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb2 adrenoceptor beta 2 JBrowse link 18 57,513,792 57,515,834 RGD:1624291
RGD:1600115
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:1624291
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:5509896
RGD:1624291
G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Arr3 arrestin 3 JBrowse link X 70,438,590 70,452,140 RGD:13792537
G Arrb1 arrestin, beta 1 JBrowse link 1 164,502,099 164,573,947 RGD:1624291
RGD:13792537
G Arrb2 arrestin, beta 2 JBrowse link 10 57,040,252 57,048,045 RGD:1624291
RGD:13792537
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:1624291
G Dnm1 dynamin 1 JBrowse link 3 11,338,081 11,382,043 RGD:9685157
G Dnm2 dynamin 2 JBrowse link 8 22,458,869 22,540,649 RGD:9685157
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:1581465
G Drd3 dopamine receptor D3 JBrowse link 11 61,819,102 61,883,223 RGD:1581465
RGD:1624291
G Grk4 G protein-coupled receptor kinase 4 JBrowse link 14 81,261,708 81,339,516 RGD:1304268
G Htr1b 5-hydroxytryptamine receptor 1B JBrowse link 8 89,113,984 89,130,830 RGD:1624291
G Htr2b 5-hydroxytryptamine receptor 2B JBrowse link 9 93,112,781 93,130,135 RGD:1600115
RGD:1624291
G Pld2 phospholipase D2 JBrowse link 10 57,161,921 57,181,148 RGD:1624291
G Sag S-antigen visual arrestin JBrowse link 9 94,926,901 94,972,162 RGD:13792537
inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2b calcium/calmodulin-dependent protein kinase II beta JBrowse link 14 86,208,876 86,297,727 RGD:1624291
negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Necab2 N-terminal EF-hand calcium binding protein 2 JBrowse link 19 52,086,325 52,112,633 RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
positive regulation of G protein-coupled receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apln apelin JBrowse link X 134,856,719 134,866,210 RGD:12907555
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
positive regulation of inhibitory G protein-coupled receptor phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aplnr apelin receptor JBrowse link 3 72,540,538 72,544,183 RGD:1624291
RGD:1600115
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043344
prostaglandin receptor internalization term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:10043344

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.