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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain-hindbrain boundary maturation during brain development
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Accession:GO:0022004 term browser browse the term
Definition:A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.


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midbrain-hindbrain boundary maturation during brain development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 ISO MGI:1856382 (MGI:76584|PMID:8555108) RGD PMID:8555108 MGI:76584 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
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  biological_process 20020
    multicellular organismal process 9047
      midbrain-hindbrain boundary maturation during brain development 1
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  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          embryo development 1307
            embryo development ending in birth or egg hatching 861
              chordate embryonic development 845
                neural tube development 196
                  neural tube patterning 49
                    rostrocaudal neural tube patterning 14
                      midbrain-hindbrain boundary development 9
                        midbrain-hindbrain boundary maturation 1
                          midbrain-hindbrain boundary maturation during brain development 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.