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ONTOLOGY REPORT - ANNOTATIONS


Term:forebrain neuron development
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Accession:GO:0021884 term browser browse the term
Definition:The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.



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forebrain neuron development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf8 fibroblast growth factor 8 IMP induction of dopaminergic neurons in the rostral forebrain RGD PMID:9630220 RGD:2289424 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359
JBrowse link
G Gbx2 gastrulation brain homeobox 2 acts_upstream_of_or_within ISO MGI:1857634 (PMID:21048141) RGD PMID:21048141 NCBI chr 9:90,509,633...90,512,212
Ensembl chr 9:90,509,633...90,512,212
JBrowse link
G Gnaq G protein subunit alpha q involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2151661 (PMID:15340067)
Ensembl
RGD
PMID:15340067 GO_REF:0000107 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Lhx6 LIM homeobox 6 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1096343 (PMID:15217369)
GO_Central
RGD
PMID:15217369 GO_REF:0000033 NCBI chr 3:19,432,439...19,456,268
Ensembl chr 3:19,433,494...19,456,061
JBrowse link
G Lhx8 LIM homeobox 8 involved_in
acts_upstream_of_or_within
IBA
ISO
GO_REF:0000033
MGI:1306803 (PMID:15217369)
GO_Central
RGD
PMID:15217369 GO_REF:0000033 NCBI chr 2:243,244,958...243,269,624
Ensembl chr 2:243,244,961...243,269,416
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:19453629)
UniProt
RGD
PMID:19453629 GO_REF:0000024 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247
JBrowse link
G Secisbp2 SECIS binding protein 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2181426|MGI:5583885 (PMID:24844465)
Ensembl
RGD
PMID:24844465 GO_REF:0000107 NCBI chr17:13,538,513...13,569,573
Ensembl chr17:13,538,513...13,569,523
JBrowse link
G Sox1 SRY-box transcription factor 1 acts_upstream_of_or_within ISO MGI:2137412 (PMID:15882093) RGD PMID:15882093 NCBI chr16:77,135,577...77,139,592
Ensembl chr16:77,137,584...77,138,762
JBrowse link
G Tfap2a transcription factor AP-2 alpha acts_upstream_of_or_within ISO MGI:1888387 (PMID:10803593) RGD PMID:10803593 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
JBrowse link
gonadotrophin-releasing hormone neuronal migration to the hypothalamus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndnf neuron-derived neurotrophic factor involved_in ISO (PMID:31883645) RGD PMID:31883645 NCBI chr 4:94,944,392...94,981,871
Ensembl chr 4:94,944,360...94,981,873
JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (PMID:21059704) RGD PMID:21059704 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nrp2 neuropilin 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:21059704)
Ensembl
RGD
PMID:21059704 GO_REF:0000107 NCBI chr 9:64,122,815...64,238,007
Ensembl chr 9:64,123,132...64,237,958
JBrowse link
G Plxna1 plexin A1 involved_in ISO UniProtKB:P70208 (PMID:31690636) RGD PMID:31690636 NCBI chr 4:121,737,934...121,782,901
Ensembl chr 4:121,737,945...122,024,196
JBrowse link
G Plxna3 plexin A3 involved_in ISO UniProtKB:P70206 (PMID:31690636) RGD PMID:31690636 NCBI chr  X:152,115,699...152,131,608
Ensembl chr  X:152,115,819...152,131,603
JBrowse link
G Sema3a semaphorin 3A involved_in ISO (PMID:21059704) RGD PMID:21059704 NCBI chr 4:21,282,398...21,754,834
Ensembl chr 4:21,287,982...21,494,432
JBrowse link
G Sema3e semaphorin 3E involved_in ISO (PMID:25985275) RGD PMID:25985275 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229
JBrowse link
hypothalamus gonadotrophin-releasing hormone neuron development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nhlh2 nescient helix loop helix 2 acts_upstream_of_or_within_positive_effect ISO (PMID:23785158) RGD PMID:23785158 NCBI chr 2:189,444,287...189,449,625
Ensembl chr 2:189,442,711...189,449,625
JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO MGI:3774112 (PMID:18299572) RGD PMID:18299572 NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
pyramidal neuron development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2386545|MGI:3587769 (PMID:16625205) RGD PMID:16625205 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (PMID:2473662) RGD PMID:2473662 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Dclk2 doublecortin-like kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1277171 (PMID:19342486)
Ensembl
RGD
PMID:19342486 GO_REF:0000107 NCBI chr 2:172,202,733...172,338,411
Ensembl chr 2:172,208,706...172,338,250
JBrowse link
G Dcx doublecortin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1918012 (PMID:19342486)
Ensembl
RGD
PMID:19342486 GO_REF:0000107 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 involved_in ISO (PMID:20410112) RGD PMID:20410112 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Ogdh oxoglutarate dehydrogenase involved_in IEA
ISO
GO_REF:0000107
(PMID:16901643)
Ensembl
RGD
PMID:16901643 GO_REF:0000107 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Plxna3 plexin A3 acts_upstream_of_or_within ISO MGI:2386961 (PMID:11683995) RGD PMID:11683995 NCBI chr  X:152,115,699...152,131,608
Ensembl chr  X:152,115,819...152,131,603
JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:26203146) RGD PMID:26203146 NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305
JBrowse link
G Slc4a10 solute carrier family 4 member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3774019 (PMID:18165320)
Ensembl
RGD
PMID:18165320 GO_REF:0000107 NCBI chr 3:46,665,076...46,959,088
Ensembl chr 3:46,665,265...46,957,268
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII involved_in ISO (PMID:16901643) RGD PMID:16901643 NCBI chr10:37,585,864...37,589,328
Ensembl chr10:37,586,888...37,589,169
JBrowse link
pyramidal neuron migration to cerebral cortex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Disc1 DISC1 scaffold protein IMP RGD PMID:16299498 RGD:5509783 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Foxg1 forkhead box G1 acts_upstream_of_or_within ISO (PMID:22726835) RGD PMID:22726835 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:30639322) RGD PMID:30639322 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20536
    developmental process 7105
      anatomical structure development 6607
        cell development 3337
          neuron development 1418
            central nervous system neuron development 114
              forebrain neuron development 30
                hypothalamus gonadotrophin-releasing hormone neuron development + 9
                pyramidal neuron development + 13
Path 2
Term Annotations click to browse term
  biological_process 20536
    developmental process 7105
      anatomical structure development 6607
        multicellular organism development 5324
          system development 4606
            nervous system development 2859
              neurogenesis 2114
                generation of neurons 1807
                  neuron differentiation 1728
                    central nervous system neuron differentiation 254
                      forebrain neuron differentiation 55
                        forebrain neuron development 30
                          hypothalamus gonadotrophin-releasing hormone neuron development + 9
                          pyramidal neuron development + 13
paths to the root