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ONTOLOGY REPORT - ANNOTATIONS


Term:pyramidal neuron differentiation
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Accession:GO:0021859 term browser browse the term
Definition:The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.
Synonyms:broad_synonym: projection neuron differentiation



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pyramidal neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of ISO (PMID:23160044) RGD PMID:23160044 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912) RGD PMID:17954912 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263
JBrowse link
G Tuba1a tubulin, alpha 1A involved_in ISO MGI:5308811 (PMID:22101068) RGD PMID:22101068 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Ulk4 unc-51 like kinase 4 acts_upstream_of_or_within ISO (PMID:35522199) RGD PMID:35522199 NCBI chr 8:120,670,879...120,966,026
Ensembl chr 8:120,670,866...120,966,924
JBrowse link
G Unc5d unc-5 netrin receptor D acts_upstream_of_or_within ISO (PMID:22726835) RGD PMID:22726835 NCBI chr16:62,860,119...63,406,932
Ensembl chr16:62,860,174...63,401,143
JBrowse link
hippocampal pyramidal neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 acts_upstream_of_or_within ISO (PMID:15608631) RGD PMID:15608631 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071
JBrowse link
pyramidal neuron development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atg7 autophagy related 7 acts_upstream_of_or_within ISO MGI:2386545|MGI:3587769 (PMID:16625205) RGD PMID:16625205 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (PMID:2473662) RGD PMID:2473662 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354
JBrowse link
G Dclk2 doublecortin-like kinase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1277171 (PMID:19342486)
Ensembl
RGD
PMID:19342486 GO_REF:0000107 NCBI chr 2:172,202,733...172,338,411
Ensembl chr 2:172,208,706...172,338,250
JBrowse link
G Dcx doublecortin involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1918012 (PMID:19342486)
Ensembl
RGD
PMID:19342486 GO_REF:0000107 NCBI chr  X:107,430,767...107,573,612
Ensembl chr  X:107,430,767...107,507,476
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 involved_in ISO (PMID:20410112) RGD PMID:20410112 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626
JBrowse link
G Ogdh oxoglutarate dehydrogenase involved_in IEA
ISO
GO_REF:0000107
(PMID:16901643)
Ensembl
RGD
PMID:16901643 GO_REF:0000107 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Plxna3 plexin A3 acts_upstream_of_or_within ISO MGI:2386961 (PMID:11683995) RGD PMID:11683995 NCBI chr  X:152,115,699...152,131,608
Ensembl chr  X:152,115,819...152,131,603
JBrowse link
G Scyl2 SCY1 like pseudokinase 2 involved_in ISO (PMID:26203146) RGD PMID:26203146 NCBI chr 7:24,064,404...24,117,338
Ensembl chr 7:24,064,404...24,117,305
JBrowse link
G Slc4a10 solute carrier family 4 member 10 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3774019 (PMID:18165320)
Ensembl
RGD
PMID:18165320 GO_REF:0000107 NCBI chr 3:46,665,076...46,959,088
Ensembl chr 3:46,665,265...46,957,268
JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII involved_in ISO (PMID:16901643) RGD PMID:16901643 NCBI chr10:37,585,864...37,589,328
Ensembl chr10:37,586,888...37,589,169
JBrowse link
pyramidal neuron migration to cerebral cortex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Disc1 DISC1 scaffold protein IMP RGD PMID:16299498 RGD:5509783 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Foxg1 forkhead box G1 acts_upstream_of_or_within ISO (PMID:22726835) RGD PMID:22726835 NCBI chr 6:66,674,797...66,677,611
Ensembl chr 6:66,666,587...66,678,607
JBrowse link
G Zmiz1 zinc finger, MIZ-type containing 1 involved_in ISO (PMID:30639322) RGD PMID:30639322 NCBI chr16:1,027,083...1,232,616
Ensembl chr16:1,027,325...1,232,597
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    cellular process 19154
      cellular developmental process 4781
        cell differentiation 4780
          neuron differentiation 1722
            pyramidal neuron differentiation 19
              Meynert cell differentiation 0
              hippocampal pyramidal neuron differentiation 1
              pyramidal neuron development + 13
Path 2
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      anatomical structure development 6572
        multicellular organism development 5298
          system development 4583
            nervous system development 2847
              neurogenesis 2110
                generation of neurons 1807
                  neuron differentiation 1722
                    pyramidal neuron differentiation 19
                      Meynert cell differentiation 0
                      hippocampal pyramidal neuron differentiation 1
                      pyramidal neuron development + 13
paths to the root