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ONTOLOGY REPORT - ANNOTATIONS

Term:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
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Accession:GO:0021776 term browser browse the term
Definition:The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
Synonyms:exact_synonym: hedgehog signaling pathway involved in spinal cord motor neuron cell fate specification;   hh signaling pathway involved in spinal cord motor neuron cell fate specification;   smoothened signalling pathway involved in spinal cord motor neuron cell fate specification


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smoothened signaling pathway involved in spinal cord motor neuron cell fate specification term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15215207) Ensembl
MGI		 PMID:15215207 GO_REF:0000107 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G SUFU SUFU negative regulator of hedgehog signaling involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19684112) Ensembl
MGI		 PMID:19684112 GO_REF:0000107 NCBI chr28:14,992,989...15,115,499
Ensembl chr28:14,992,618...15,112,389 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17878
    developmental process 6855
      anatomical structure development 6433
        ventral spinal cord development 56
          spinal cord motor neuron differentiation 40
            spinal cord motor neuron cell fate specification 11
              smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
Path 2
Term Annotations click to browse term
  biological_process 17878
    developmental process 6855
      anatomical structure development 6433
        multicellular organism development 5182
          system development 4509
            nervous system development 2787
              neurogenesis 2079
                generation of neurons 1795
                  neuron differentiation 1714
                    central nervous system neuron differentiation 222
                      spinal cord motor neuron differentiation 40
                        spinal cord motor neuron cell fate specification 11
                          smoothened signaling pathway involved in spinal cord motor neuron cell fate specification 3
paths to the root