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ONTOLOGY REPORT - ANNOTATIONS


Term:midbrain-hindbrain boundary maturation
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Accession:GO:0021732 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
Synonyms:related_synonym: MHB maturation;   isthmus maturation


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midbrain-hindbrain boundary maturation during brain development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO (MGI:76584|PMID:8555108) MGI PMID:8555108 MGI:76584 NCBI chrNW_004955500:7,797,063...7,811,142
Ensembl chrNW_004955500:7,797,060...7,811,167
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Term Annotations click to browse term
  biological_process 12290
    developmental process 5825
      developmental maturation 352
        anatomical structure maturation 280
          midbrain-hindbrain boundary maturation 1
            midbrain-hindbrain boundary maturation during brain development 1
            midbrain-hindbrain boundary maturation during neural plate development 0
Path 2
Term Annotations click to browse term
  biological_process 12290
    developmental process 5825
      anatomical structure development 5464
        multicellular organism development 4525
          embryo development 1226
            embryo development ending in birth or egg hatching 817
              chordate embryonic development 801
                neural tube development 195
                  neural tube patterning 51
                    rostrocaudal neural tube patterning 14
                      midbrain-hindbrain boundary development 9
                        midbrain-hindbrain boundary maturation 1
                          midbrain-hindbrain boundary maturation during brain development 1
                          midbrain-hindbrain boundary maturation during neural plate development 0
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