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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar granule cell differentiation
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Accession:GO:0021707 term browser browse the term
Definition:The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.


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cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (MGI:1275896|PMID:9668038) MGI PMID:9668038 MGI:1275896 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007 		JBrowse link
G CBLN1 cerebellin 1 precursor involved_in ISS
IEA		 BHF-UCL
BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr16:49,277,917...49,281,838
Ensembl chr16:49,277,917...49,281,838 		JBrowse link
G GRID2 glutamate ionotropic receptor delta type subunit 2 involved_in ISS
IEA		 BHF-UCL
BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:92,303,966...93,810,456
Ensembl chr 4:92,303,966...93,810,157 		JBrowse link
G KNDC1 kinase non-catalytic C-lobe domain containing 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (MGI:3769586|PMID:17984326) UniProt
MGI
Ensembl
UniProt		 PMID:17984326 GO_REF:0000024 GO_REF:0000107 MGI:3769586 NCBI chr10:133,160,219...133,226,412
Ensembl chr10:133,160,219...133,226,412 		JBrowse link
G MTPN myotrophin involved_in ISO
IEA		 RGD
Ensembl
Ensembl		 PMID:8144589 GO_REF:0000107 RGD:632797 NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359 		JBrowse link
G NFIX nuclear factor I X acts_upstream_of_or_within ISO (MGI:5436217|PMID:21800304) MGI PMID:21800304 MGI:5436217 NCBI chr19:12,995,475...13,098,796
Ensembl chr19:12,995,475...13,098,796 		JBrowse link
G NRXN1 neurexin 1 involved_in ISS BHF-UCL
BHF-UCL		 GO_REF:0000024 NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575 		JBrowse link
G OPHN1 oligophrenin 1 involved_in IMP (PMID:27160703) ARUK-UCL
ARUK-UCL		 PMID:27160703 NCBI chr  X:68,042,344...68,433,841
Ensembl chr  X:67,949,349...68,433,913 		JBrowse link
G PROX1 prospero homeobox 1 involved_in ISS
IEA		 BHF-UCL
Ensembl
BHF-UCL		 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:213,983,151...214,041,510
Ensembl chr 1:213,983,181...214,041,510 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G ULK1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (MGI:1351063|PMID:10624947) MGI PMID:10624947 MGI:1351063 NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150 		JBrowse link
G WNT7A Wnt family member 7A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1195230|PMID:9405095) Ensembl
MGI
Ensembl		 PMID:9405095 GO_REF:0000107 MGI:1195230 NCBI chr 3:13,816,258...13,880,071
Ensembl chr 3:13,816,258...13,880,071 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19665
    developmental process 7549
      anatomical structure formation involved in morphogenesis 1431
        cerebellar granular layer formation 12
          cerebellar granule cell differentiation 12
Path 2
Term Annotations click to browse term
  biological_process 19665
    developmental process 7549
      anatomical structure development 6910
        multicellular organism development 5529
          system development 4803
            nervous system development 3017
              central nervous system development 1397
                brain development 1062
                  hindbrain development 230
                    metencephalon development 175
                      cerebellum development 161
                        cerebellar cortex development 72
                          cerebellar granular layer development 18
                            cerebellar granular layer morphogenesis 14
                              cerebellar granular layer formation 12
                                cerebellar granule cell differentiation 12
paths to the root