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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar cortex formation
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Accession:GO:0021697 term browser browse the term
Definition:The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.


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cerebellar cortex formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin-dependent kinase 5 acts_upstream_of_or_within ISO MGI:1861809 (MGI:1340775|PMID:10407039) RGD PMID:10407039 MGI:1340775 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:99511 (MGI:5545830|PMID:24431450)		 Ensembl
RGD		 PMID:24431450 GO_REF:0000107 MGI:5545830 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 acts_upstream_of_or_within ISO MGI:1346866|MGI:4868451 (MGI:5545830|PMID:24431450) RGD PMID:24431450 MGI:5545830 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
cerebellar granule cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857876 (MGI:1275896|PMID:9668038) RGD PMID:9668038 MGI:1275896 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Cbln1 cerebellin 1 precursor involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q61625 (MGI:4839424|PMID:20537373)		 BHF-UCL
RGD		 PMID:20537373 GO_REF:0000024 MGI:4839424 NCBI chr19:19,608,763...19,612,572
Ensembl chr19:19,608,716...19,612,572 		JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q9R171 (MGI:4839424|PMID:20537373)		 BHF-UCL
RGD		 PMID:20537373 GO_REF:0000024 MGI:4839424 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355 		JBrowse link
G Kndc1 kinase non-catalytic C-lobe domain containing 1 acts_upstream_of_or_within ISO (MGI:3769586|PMID:17984326) RGD PMID:17984326 MGI:3769586 NCBI chr 1:194,689,962...194,738,353
Ensembl chr 1:194,690,135...194,738,362 		JBrowse link
G Mtpn myotrophin IEP RGD PMID:8144589 RGD:632797 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Nfix nuclear factor I X acts_upstream_of_or_within
involved_in		 ISO MGI:3802571 (MGI:5436217|PMID:21800304)
MGI:3802571 (MGI:5612951|PMID:23042739)		 RGD PMID:21800304 PMID:23042739 MGI:5436217 MGI:5612951 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nrxn1 neurexin 1 involved_in ISS
ISO		 GO_REF:0000024
UniProtKB:Q61625|UniProtKB:Q9R171 (MGI:4839424|PMID:20537373)		 BHF-UCL
RGD		 PMID:20537373 GO_REF:0000024 MGI:4839424 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ophn1 oligophrenin 1 involved_in ISO (PMID:27160703) RGD PMID:27160703 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633 		JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (MGI:4849596|PMID:20808958) RGD PMID:20808958 MGI:4849596 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183 		JBrowse link
G Top2a DNA topoisomerase II alpha IEP RGD PMID:11170002 RGD:8693630 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 acts_upstream_of_or_within ISO (MGI:1351063|PMID:10624947) RGD PMID:10624947 MGI:1351063 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Wnt7a Wnt family member 7A acts_upstream_of_or_within ISO (MGI:1195230|PMID:9405095) RGD PMID:9405095 MGI:1195230 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
cerebellar molecular layer formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5504540|PMID:23688253)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23688253 GO_REF:0000024 GO_REF:0000107 MGI:5504540 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
cerebellar Purkinje cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within
involved_in		 ISO MGI:1856535|MGI:1857523|MGI:2443047|MGI:6270378 (MGI:1347769|PMID:10630211), (MGI:6269036|PMID:30420556)
(MGI:2159417|PMID:11884758), (MGI:3614720|PMID:16465590), (MGI:4849873|PMID:21074048)		 RGD PMID:10630211 PMID:11884758 PMID:16465590 PMID:21074048 PMID:30420556 MGI:1347769 MGI:2159417 MGI:3614720 MGI:4849873 MGI:6269036 NCBI chr17:5,120,540...5,238,874
Ensembl chr17:5,120,609...5,238,869 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857876 (MGI:1275896|PMID:9668038) RGD PMID:9668038 MGI:1275896 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (MGI:71790|PMID:2473662) RGD PMID:2473662 MGI:71790 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atxn2 ataxin 2 acts_upstream_of_or_within ISO MGI:3505741 (MGI:3510013|PMID:10973246) RGD PMID:10973246 MGI:3510013 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209|MGI:1856210 (MGI:1347769|PMID:10630211), (MGI:62667|PMID:1306163), (MGI:68980|PMID:7834360) RGD PMID:1306163 PMID:7834360 PMID:10630211 MGI:1347769 MGI:62667 MGI:68980 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cend1 cell cycle exit and neuronal differentiation 1 acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:4831137 (MGI:4830814|PMID:20153830)
PMID:21873635		 RGD PMID:20153830 PMID:21873635 MGI:4830814, RGD:13792537 NCBI chr 1:196,525,153...196,528,152
Ensembl chr 1:196,523,920...196,528,302 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5295128|PMID:21957071)		 UniProt
Ensembl
RGD		 PMID:21957071 GO_REF:0000024 GO_REF:0000107 MGI:5295128 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Foxp2 forkhead box P2 involved_in ISO MGI:3778383 (MGI:5306536|PMID:22133810) RGD PMID:22133810 MGI:5306536 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 acts_upstream_of_or_within ISO MGI:3613033 (MGI:4461108|PMID:20041218) RGD PMID:20041218 MGI:4461108 NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312 		JBrowse link
G Ldb1 LIM domain binding 1 acts_upstream_of_or_within ISO MGI:3719683 (MGI:3718715|PMID:17664423) RGD PMID:17664423 MGI:3718715 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:107792 (MGI:3718715|PMID:17664423)		 UniProt
RGD		 PMID:17664423 GO_REF:0000024 MGI:3718715 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Lhx5 LIM homeobox 5 acts_upstream_of_or_within ISO MGI:99783 (MGI:3718715|PMID:17664423) RGD PMID:17664423 MGI:3718715 NCBI chr12:36,126,186...36,134,625
Ensembl chr12:36,126,186...36,134,625 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:3521746 (MGI:3512714|PMID:15345707) RGD PMID:15345707 MGI:3512714 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO MGI:1857035 (MGI:86446|PMID:8996814) RGD PMID:8996814 MGI:86446 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (MGI:5300220|PMID:21937600), (MGI:5565016|PMID:24491816) RGD PMID:21937600 PMID:24491816 MGI:5300220 MGI:5565016 NCBI chr18:70,404,431...70,446,330
Ensembl chr18:70,404,489...70,440,342 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 acts_upstream_of_or_within ISO MGI:6358090 (MGI:5921109|PMID:28934388) RGD PMID:28934388 MGI:5921109 NCBI chr18:23,215,954...23,244,917
Ensembl chr18:23,215,962...23,244,314 		JBrowse link
G Top2a DNA topoisomerase II alpha IEP RGD PMID:11170002 RGD:8693630 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2137515|MGI:2152544|MGI:2179048|MGI:5587034 (MGI:6152587|PMID:29615573) RGD PMID:29615573 MGI:6152587 NCBI chr 3:50,861,367...50,935,782
Ensembl chr 3:50,861,367...50,935,903 		JBrowse link
G Ttll1 TTL family tubulin polyglutamylase complex subunit L1 acts_upstream_of_or_within ISO MGI:1918244 (MGI:6269036|PMID:30420556) RGD PMID:30420556 MGI:6269036 NCBI chr 7:114,619,509...114,648,850
Ensembl chr 7:114,619,508...114,648,761 		JBrowse link
cerebellar Purkinje cell layer formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta acts_upstream_of_or_within ISO (MGI:3762988|PMID:17954912) RGD PMID:17954912 MGI:3762988 NCBI chr 2:174,609,437...174,615,457
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Whrn whirlin involved_in IEA
ISO		 GO_REF:0000107
(MGI:5516521|PMID:24011083)		 Ensembl
RGD		 PMID:24011083 GO_REF:0000107 MGI:5516521 NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19738
    developmental process 6867
      anatomical structure formation involved in morphogenesis 1342
        cerebellar cortex formation 35
          Lugaro cell differentiation 0
          cerebellar Purkinje cell layer formation + 21
          cerebellar granular layer formation + 12
          cerebellar molecular layer formation + 1
          eurydendroid cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 19738
    developmental process 6867
      anatomical structure development 6387
        multicellular organism development 5151
          system development 4434
            nervous system development 2716
              central nervous system development 1193
                brain development 892
                  hindbrain development 227
                    metencephalon development 173
                      cerebellum development 159
                        cerebellum morphogenesis 60
                          cerebellar cortex morphogenesis 49
                            cerebellar cortex formation 35
                              Lugaro cell differentiation 0
                              cerebellar Purkinje cell layer formation + 21
                              cerebellar granular layer formation + 12
                              cerebellar molecular layer formation + 1
                              eurydendroid cell differentiation 0
paths to the root