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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar Purkinje cell layer formation
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Accession:GO:0021694 term browser browse the term
Definition:The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


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cerebellar Purkinje cell layer formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GBA1 glucosylceramidase beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17954912) Ensembl
MGI		 PMID:17954912 GO_REF:0000107 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G WHRN whirlin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:114,402,080...114,505,473
Ensembl chr 9:114,402,080...114,505,473 		JBrowse link
cerebellar Purkinje cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTPBP1 ATP/GTP binding carboxypeptidase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
ISS		 (PMID:10630211)
(PMID:30420556)		 Ensembl
MGI
UniProt		 PMID:10630211 PMID:30420556 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:85,546,539...85,805,483
Ensembl chr 9:85,546,539...85,742,029 		JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO (PMID:9668038) MGI PMID:9668038 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007 		JBrowse link
G ATP7A ATPase copper transporting alpha involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:2473662) UniProt
MGI		 PMID:2473662 GO_REF:0000024 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G ATXN2 ataxin 2 acts_upstream_of_or_within ISO (PMID:10973246) MGI PMID:10973246 NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO (PMID:7834360)
(PMID:1306163)
(PMID:10630211)		 MGI PMID:1306163 PMID:7834360 PMID:10630211 NCBI chr19:13,206,442...13,506,479
Ensembl chr19:13,206,442...13,633,025 		JBrowse link
G CEND1 cell cycle exit and neuronal differentiation 1 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:20153830) Ensembl
MGI
TreeGrafter
GO_Central		 PMID:20153830 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr11:787,115...790,090
Ensembl chr11:787,115...790,113 		JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:49,866,896...49,903,900
Ensembl chr12:49,866,896...49,904,217 		JBrowse link
G FOXP2 forkhead box P2 involved_in ISO (PMID:22133810) MGI PMID:22133810 NCBI chr 7:114,086,327...114,693,765
Ensembl chr 7:114,086,327...114,693,772 		JBrowse link
G HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20041218) Ensembl
MGI		 PMID:20041218 GO_REF:0000107 NCBI chr15:63,608,618...63,833,948
Ensembl chr15:63,608,618...63,833,948 		JBrowse link
G LDB1 LIM domain binding 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17664423) Ensembl
MGI		 PMID:17664423 GO_REF:0000107 NCBI chr10:102,102,088...102,121,442
Ensembl chr10:102,106,489...102,120,368 		JBrowse link
G LHX1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:17664423) UniProt
MGI
Ensembl		 PMID:17664423 GO_REF:0000024 GO_REF:0000107 NCBI chr17:36,936,785...36,944,612
Ensembl chr17:36,936,785...36,944,612 		JBrowse link
G LHX5 LIM homeobox 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17664423) Ensembl
MGI		 PMID:17664423 GO_REF:0000107 NCBI chr12:113,462,033...113,471,871
Ensembl chr12:113,462,033...113,472,280 		JBrowse link
G PSAP prosaposin acts_upstream_of_or_within ISO (PMID:15345707) MGI PMID:15345707 NCBI chr10:71,816,298...71,851,251
Ensembl chr10:71,816,298...71,851,251 		JBrowse link
G RORA RAR related orphan receptor A involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8996814) Ensembl
MGI		 PMID:8996814 GO_REF:0000107 NCBI chr15:60,488,284...61,229,302
Ensembl chr15:60,488,284...61,229,302 		JBrowse link
G SKOR2 SKI family transcriptional corepressor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24491816)
(PMID:21937600)		 Ensembl
MGI		 PMID:21937600 PMID:24491816 GO_REF:0000107 NCBI chr18:47,206,169...47,251,660
Ensembl chr18:47,206,169...47,251,660 		JBrowse link
G SLC25A46 solute carrier family 25 member 46 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28934388) Ensembl
MGI		 PMID:28934388 GO_REF:0000107 NCBI chr 5:110,738,145...110,765,157
Ensembl chr 5:110,738,136...110,765,161 		JBrowse link
G TOP2A DNA topoisomerase II alpha ISO RGD PMID:11170002 RGD:8693630 NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896 		JBrowse link
G TTC21B tetratricopeptide repeat domain 21B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:29615573) Ensembl
MGI		 PMID:29615573 GO_REF:0000107 NCBI chr 2:165,873,362...165,953,776
Ensembl chr 2:165,857,475...165,953,851 		JBrowse link
G TTLL1 TTL family tubulin polyglutamylase complex subunit L1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:30420556) Ensembl
MGI		 PMID:30420556 GO_REF:0000107 NCBI chr22:43,039,516...43,089,391
Ensembl chr22:43,039,516...43,089,419 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19669
    developmental process 7610
      anatomical structure formation involved in morphogenesis 1478
        cerebellar Purkinje cell layer formation 21
          candelabrum cell differentiation 0
          cerebellar Purkinje cell differentiation 19
Path 2
Term Annotations click to browse term
  biological_process 19669
    developmental process 7610
      anatomical structure development 7020
        multicellular organism development 5632
          system development 4908
            nervous system development 3048
              central nervous system development 1301
                brain development 950
                  hindbrain development 234
                    metencephalon development 179
                      cerebellum development 165
                        cerebellar cortex development 74
                          cerebellar Purkinje cell layer development 40
                            cerebellar Purkinje cell layer morphogenesis 26
                              cerebellar Purkinje cell layer formation 21
                                candelabrum cell differentiation 0
                                cerebellar Purkinje cell differentiation 19
paths to the root