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ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar Purkinje cell layer formation
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Accession:GO:0021694 term browser browse the term
Definition:The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.

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cerebellar Purkinje cell layer formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba glucosylceramidase beta acts_upstream_of_or_within ISO (MGI:3762988|PMID:17954912) RGD PMID:17954912 MGI:3762988 NCBI chr 2:188,511,781...188,522,602
Ensembl chr 2:188,516,582...188,522,601 		JBrowse link
G Whrn whirlin involved_in IEA
ISO		 GO_REF:0000107
(MGI:5516521|PMID:24011083)		 Ensembl
RGD		 PMID:24011083 GO_REF:0000107 MGI:5516521 NCBI chr 5:79,235,541...79,317,206
Ensembl chr 5:79,234,950...79,317,206 		JBrowse link
cerebellar Purkinje cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr17:5,510,009...5,614,416
Ensembl chr17:5,511,385...5,614,435 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857876 (MGI:1275896|PMID:9668038) RGD PMID:9668038 MGI:1275896 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (MGI:71790|PMID:2473662) RGD PMID:2473662 MGI:71790 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644 		JBrowse link
G Atxn2 ataxin 2 acts_upstream_of_or_within ISO MGI:3505741 (MGI:3510013|PMID:10973246) RGD PMID:10973246 MGI:3510013 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209|MGI:1856210 (MGI:1347769|PMID:10630211), (MGI:62667|PMID:1306163), (MGI:68980|PMID:7834360) RGD PMID:1306163 PMID:7834360 PMID:10630211 MGI:1347769 MGI:62667 MGI:68980 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550 		JBrowse link
G Cend1 cell cycle exit and neuronal differentiation 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:4831137 (MGI:4830814|PMID:20153830)		 RGD PMID:20153830, PMID:21873635 MGI:4830814, RGD:13792537 NCBI chr 1:214,407,072...214,410,069
Ensembl chr 1:214,408,100...214,408,549
Ensembl chr 1:214,408,100...214,408,549 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5295128|PMID:21957071)		 UniProt
RGD		 PMID:21957071 GO_REF:0000024 MGI:5295128 NCBI chr 7:141,158,769...141,185,781
Ensembl chr 7:141,157,963...141,185,710 		JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 acts_upstream_of_or_within ISO MGI:3613033 (MGI:4461108|PMID:20041218) RGD PMID:20041218 MGI:4461108 NCBI chr 8:72,029,550...72,198,363
Ensembl chr 8:72,029,489...72,198,358 		JBrowse link
G Ldb1 LIM domain binding 1 acts_upstream_of_or_within ISO MGI:3719683 (MGI:3718715|PMID:17664423) RGD PMID:17664423 MGI:3718715 NCBI chr 1:265,772,729...265,798,442
Ensembl chr 1:265,785,409...265,798,167 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:107792 (MGI:3718715|PMID:17664423)		 UniProt
RGD		 PMID:17664423 GO_REF:0000024 MGI:3718715 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293 		JBrowse link
G Lhx5 LIM homeobox 5 acts_upstream_of_or_within ISO MGI:99783 (MGI:3718715|PMID:17664423) RGD PMID:17664423 MGI:3718715 NCBI chr12:41,663,000...41,671,437
Ensembl chr12:41,663,000...41,671,437 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:3521746 (MGI:3512714|PMID:15345707) RGD PMID:15345707 MGI:3512714 NCBI chr20:29,831,302...29,856,876
Ensembl chr20:29,831,314...29,856,875 		JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO MGI:1857035 (MGI:86446|PMID:8996814) RGD PMID:8996814 MGI:86446 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212 		JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (MGI:5300220|PMID:21937600), (MGI:5565016|PMID:24491816) RGD PMID:21937600 PMID:24491816 MGI:5300220 MGI:5565016 NCBI chr18:73,145,596...73,199,395
Ensembl chr18:73,157,973...73,193,377 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 acts_upstream_of_or_within ISO MGI:6358090 (MGI:5921109|PMID:28934388) RGD PMID:28934388 MGI:5921109 NCBI chr18:24,369,104...24,397,412
Ensembl chr18:24,369,125...24,397,551 		JBrowse link
G Top2a DNA topoisomerase II alpha IEP RGD PMID:11170002 RGD:8693630 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2137515|MGI:2152544|MGI:2179048|MGI:5587034 (MGI:6152587|PMID:29615573) RGD PMID:29615573 MGI:6152587 NCBI chr 3:52,286,794...52,361,060
Ensembl chr 3:52,286,794...52,361,060 		JBrowse link
G Ttll1 tubulin tyrosine ligase like 1 acts_upstream_of_or_within ISO MGI:1918244 (MGI:6269036|PMID:30420556) RGD PMID:30420556 MGI:6269036 NCBI chr 7:124,338,396...124,367,719
Ensembl chr 7:124,338,395...124,367,630 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      anatomical structure formation involved in morphogenesis 1215
        cerebellar Purkinje cell layer formation 20
          candelabrum cell differentiation 0
          cerebellar Purkinje cell differentiation 18
Path 2
Term Annotations click to browse term
  biological_process 19634
    developmental process 6783
      anatomical structure development 6259
        multicellular organism development 5741
          system development 5284
            nervous system development 2718
              central nervous system development 1268
                brain development 972
                  hindbrain development 218
                    metencephalon development 166
                      cerebellum development 153
                        cerebellar cortex development 68
                          cerebellar Purkinje cell layer development 38
                            cerebellar Purkinje cell layer morphogenesis 24
                              cerebellar Purkinje cell layer formation 20
                                candelabrum cell differentiation 0
                                cerebellar Purkinje cell differentiation 18
paths to the root