Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:cerebellar Purkinje cell layer morphogenesis
go back to main search page
Accession:GO:0021692 term browser browse the term
Definition:The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


show annotations for term's descendants           Sort by:
cerebellar Purkinje cell layer morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857876 (PMID:17409239) RGD PMID:17409239 NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO (PMID:32675284) RGD PMID:32675284 NCBI chr 4:74,109,455...76,366,434
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Coq8b coenzyme Q8B involved_in ISS
ISO		 GO_REF:0000024
(PMID:27499294)		 UniProt
RGD		 PMID:27499294 GO_REF:0000024 NCBI chr 1:82,525,578...82,549,182
Ensembl chr 1:82,526,568...82,549,180 		JBrowse link
G Sptbn2 spectrin, beta, non-erythrocytic 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4127354 (PMID:20231455)		 Ensembl
RGD		 PMID:20231455 GO_REF:0000107 NCBI chr 1:202,002,970...202,045,343
Ensembl chr 1:202,002,970...202,044,283 		JBrowse link
cerebellar Purkinje cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtpbp1 ATP/GTP binding carboxypeptidase 1 acts_upstream_of_or_within
involved_in		 ISO MGI:1856535|MGI:1857523|MGI:2443047|MGI:6270378 (PMID:10630211), (PMID:30420556)
(PMID:11884758), (PMID:16465590), (PMID:21074048)		 RGD PMID:10630211 PMID:11884758 PMID:16465590 PMID:21074048 PMID:30420556 NCBI chr17:5,092,108...5,244,414
Ensembl chr17:5,120,609...5,238,869 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 acts_upstream_of_or_within ISO MGI:1857876 (PMID:9668038) RGD PMID:9668038 NCBI chr 4:148,450,207...148,763,653
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Atp7a ATPase copper transporting alpha acts_upstream_of_or_within ISO MGI:1856466 (PMID:2473662) RGD PMID:2473662 NCBI chr  X:75,159,635...75,267,094
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atxn2 ataxin 2 acts_upstream_of_or_within ISO MGI:3505741 (PMID:10973246) RGD PMID:10973246 NCBI chr12:34,754,132...34,851,175
Ensembl chr12:34,754,137...34,851,479 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209|MGI:1856210 (PMID:10630211), (PMID:1306163), (PMID:7834360) RGD PMID:1306163 PMID:7834360 PMID:10630211 NCBI chr19:40,425,560...40,724,810
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Cend1 cell cycle exit and neuronal differentiation 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:4831137 (PMID:20153830)		 GO_Central
RGD		 PMID:20153830 GO_REF:0000033 NCBI chr 1:196,525,153...196,528,152
Ensembl chr 1:196,523,920...196,528,302 		JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:21957071)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:21957071 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168 		JBrowse link
G Foxp2 forkhead box P2 involved_in ISO MGI:3778383 (PMID:22133810) RGD PMID:22133810 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 acts_upstream_of_or_within ISO MGI:3613033 (PMID:20041218) RGD PMID:20041218 NCBI chr 8:66,857,169...67,070,318
Ensembl chr 8:66,856,935...67,070,312 		JBrowse link
G Ldb1 LIM domain binding 1 acts_upstream_of_or_within ISO MGI:3719683 (PMID:17664423) RGD PMID:17664423 NCBI chr 1:244,864,168...244,890,007
Ensembl chr 1:244,877,173...244,890,013 		JBrowse link
G Lhx1 LIM homeobox 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:107792 (PMID:17664423)		 UniProt
RGD		 PMID:17664423 GO_REF:0000024 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Lhx5 LIM homeobox 5 acts_upstream_of_or_within ISO MGI:99783 (PMID:17664423) RGD PMID:17664423 NCBI chr12:36,126,186...36,134,625
Ensembl chr12:36,126,186...36,134,625 		JBrowse link
G Psap prosaposin acts_upstream_of_or_within ISO MGI:3521746 (PMID:15345707) RGD PMID:15345707 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Rora RAR-related orphan receptor A acts_upstream_of_or_within ISO MGI:1857035 (PMID:8996814) RGD PMID:8996814 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Skor2 SKI family transcriptional corepressor 2 acts_upstream_of_or_within ISO MGI:5300464 (PMID:21937600), (PMID:24491816) RGD PMID:21937600 PMID:24491816 NCBI chr18:72,679,449...72,721,117
Ensembl chr18:70,404,489...70,440,342 		JBrowse link
G Slc25a46 solute carrier family 25, member 46 acts_upstream_of_or_within ISO MGI:6358090 (PMID:28934388) RGD PMID:28934388 NCBI chr18:23,215,954...23,244,917
Ensembl chr18:23,215,962...23,244,314 		JBrowse link
G Top2a DNA topoisomerase II alpha IEP RGD PMID:11170002 RGD:8693630 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B acts_upstream_of_or_within ISO MGI:2137515|MGI:2152544|MGI:2179048|MGI:5587034 (PMID:29615573) RGD PMID:29615573 NCBI chr 3:50,861,367...50,935,880
Ensembl chr 3:50,861,367...50,935,903 		JBrowse link
G Ttll1 TTL family tubulin polyglutamylase complex subunit L1 acts_upstream_of_or_within ISO MGI:1918244 (PMID:30420556) RGD PMID:30420556 NCBI chr 7:114,619,509...114,648,850
Ensembl chr 7:114,619,508...114,648,761 		JBrowse link
cerebellar Purkinje cell layer formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gba1 glucosylceramidase beta 1 acts_upstream_of_or_within ISO (PMID:17954912) RGD PMID:17954912 NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263 		JBrowse link
G Whrn whirlin involved_in IEA
ISO		 GO_REF:0000107
(PMID:24011083)		 Ensembl
RGD		 PMID:24011083 GO_REF:0000107 NCBI chr 5:76,828,308...76,911,945
Ensembl chr 5:76,828,301...76,912,223 		JBrowse link
cerebellar Purkinje cell layer structural organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dll1 delta like canonical Notch ligand 1 involved_in IEA
ISO
ISS		 GO_REF:0000107
(PMID:23688253)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:23688253 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:64,985,161...64,993,274
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Kif14 kinesin family member 14 involved_in ISO (PMID:23308235) RGD PMID:23308235 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20546
    developmental process 7139
      anatomical structure morphogenesis 3013
        cerebellar Purkinje cell layer morphogenesis 26
          cerebellar Purkinje cell layer formation + 21
          cerebellar Purkinje cell layer structural organization 2
Path 2
Term Annotations click to browse term
  biological_process 20546
    developmental process 7139
      anatomical structure development 6638
        multicellular organism development 5350
          system development 4630
            nervous system development 2868
              central nervous system development 1227
                brain development 905
                  hindbrain development 228
                    metencephalon development 174
                      cerebellum development 160
                        cerebellar cortex development 71
                          cerebellar Purkinje cell layer development 40
                            cerebellar Purkinje cell layer morphogenesis 26
                              cerebellar Purkinje cell layer formation + 21
                              cerebellar Purkinje cell layer structural organization 2
paths to the root