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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar Purkinje cell layer maturation
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Accession:GO:0021691 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


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cerebellar Purkinje cell layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arcn1 archain 1 acts_upstream_of_or_within ISO (MGI:4454933|PMID:20502676) MGI PMID:20502676 MGI:4454933 NCBI chrNW_004936542:3,605,553...3,634,889 JBrowse link
G Rere arginine-glutamic acid dipeptide repeats acts_upstream_of_or_within ISO (MGI:5582020|PMID:24466353) MGI PMID:24466353 MGI:5582020 NCBI chrNW_004936623:2,678,627...2,942,387 JBrowse link

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  biological_process 12164
    developmental process 5729
      anatomical structure development 5357
        anatomical structure maturation 262
          cerebellar Purkinje cell layer maturation 2
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  biological_process 12164
    developmental process 5729
      anatomical structure development 5357
        multicellular organism development 4905
          system development 4621
            nervous system development 2392
              central nervous system development 1148
                brain development 910
                  hindbrain development 210
                    metencephalon development 157
                      cerebellum development 143
                        cerebellar cortex development 66
                          cerebellar Purkinje cell layer development 37
                            cerebellar Purkinje cell layer maturation 2
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