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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar Purkinje cell layer maturation
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Accession:GO:0021691 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.


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cerebellar Purkinje cell layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARCN1 archain 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:4454933|PMID:20502676) Ensembl
MGI
PMID:20502676 GO_REF:0000107 MGI:4454933 NCBI chr 9:45,863,772...45,897,525
Ensembl chr 9:45,863,559...45,897,514
JBrowse link
G RERE arginine-glutamic acid dipeptide repeats acts_upstream_of_or_within ISO (MGI:5582020|PMID:24466353) MGI PMID:24466353 MGI:5582020 NCBI chr 6:68,954,766...69,258,855 JBrowse link

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Term Annotations click to browse term
  biological_process 16574
    developmental process 6328
      anatomical structure development 5845
        anatomical structure maturation 283
          cerebellar Purkinje cell layer maturation 2
Path 2
Term Annotations click to browse term
  biological_process 16574
    developmental process 6328
      anatomical structure development 5845
        multicellular organism development 5316
          system development 5008
            nervous system development 2612
              central nervous system development 1228
                brain development 954
                  hindbrain development 221
                    metencephalon development 167
                      cerebellum development 153
                        cerebellar cortex development 68
                          cerebellar Purkinje cell layer development 38
                            cerebellar Purkinje cell layer maturation 2
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