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Term:cerebellar Purkinje cell layer maturation
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Accession:GO:0021691 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.

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cerebellar Purkinje cell layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arcn1 archain 1 acts_upstream_of_or_within ISO MGI:2671790 (MGI:4454933|PMID:20502676) RGD PMID:20502676 MGI:4454933 NCBI chr 8:45,057,617...45,082,224
Ensembl chr 8:45,057,619...45,082,247
JBrowse link
G Rere arginine-glutamic acid dipeptide repeats acts_upstream_of_or_within ISO MGI:3577419 (MGI:5582020|PMID:24466353) RGD PMID:24466353 MGI:5582020 NCBI chr 5:160,765,855...161,097,678
Ensembl chr 5:160,765,934...161,097,677
JBrowse link

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  biological_process 19876
    developmental process 7031
      developmental maturation 388
        anatomical structure maturation 314
          cerebellar Purkinje cell layer maturation 2
Path 2
Term Annotations click to browse term
  biological_process 19876
    developmental process 7031
      anatomical structure development 6466
        multicellular organism development 5236
          system development 4498
            nervous system development 2807
              central nervous system development 1322
                brain development 1021
                  hindbrain development 226
                    metencephalon development 172
                      cerebellum development 158
                        cerebellar cortex development 71
                          cerebellar cortex maturation 3
                            cerebellar Purkinje cell layer maturation 2
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