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ONTOLOGY REPORT - ANNOTATIONS


Term:cerebellar granular layer maturation
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Accession:GO:0021686 term browser browse the term
Definition:A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.


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cerebellar granular layer maturation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEND1 cell cycle exit and neuronal differentiation 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:4830814|PMID:20153830)
GO_Central
MGI
PMID:20153830 PMID:21873635 MGI:4830814 NCBI chr 2:487,817...490,704
Ensembl chr 2:487,821...490,699
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16579
    developmental process 6310
      anatomical structure development 5829
        anatomical structure maturation 288
          cerebellar granular layer maturation 1
Path 2
Term Annotations click to browse term
  biological_process 16579
    developmental process 6310
      anatomical structure development 5829
        multicellular organism development 5301
          system development 4991
            nervous system development 2605
              central nervous system development 1221
                brain development 948
                  hindbrain development 220
                    metencephalon development 167
                      cerebellum development 153
                        cerebellar cortex development 68
                          cerebellar granular layer development 18
                            cerebellar granular layer maturation 1
paths to the root